Dispensing kit (6) cooperating with a dispensing device (5) for a radiopharmaceutical batch production system (1), the dispensing kit (6) having: a cassette (7) mountable on the dispensing device (5) and provided with a control hydraulic circuit (32); a tank (8) for the radiopharmaceutical, communicating with control hydraulic circuit (32); a needle assembly (9) having a needle (33) communicating with the control hydraulic circuit (32) and insertable into a container (4) to introduce a dose of radiopharmaceutical into it; a needle holder element (34) and a cap (35) couplable with each other to separate the needle (33) from the external environment when the needle (33) is not used for dispensing the radiopharmaceutical; and a conduit (39) communicating with the bottom of the cap (35) and acting as a drain when the cap (35) is coupled to the needle holder element (34) for a flushing of the dispensing kit (6). The dispensing device (5) has a movable clamp (65) and a handling device (67) for removing the cap (35) from the needle holder element ( 34 ).
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
B05B 15/55 - Arrangements for cleaningArrangements for preventing deposits, drying-out or blockageArrangements for detecting improper discharge caused by the presence of foreign matter using cleaning fluids
G21G 4/08 - Radioactive sources other than neutron sources characterised by constructional features specially adapted for medical applications
B65B 59/04 - Machines constructed with readily-detachable units or assemblies, e.g. to facilitate maintenance
2.
MODULAR CONTAINER FOR TRANSPORTING RADIOPHARMACEUTICALS OR THERMOLABILE DRUGS
A modular container (1) for carrying at least one article (34) including a radiopharmaceutical, comprising two container bodies (2) which can be coupled together and a rigid casing (3) formed by two covers (4) connected to each other by means of two connector elements (5) to hold the two container bodies (2) coupled together. Each container body (2) has a base portion (6), which has an inner face (7) that can be coupled to the inner face (7) of the other container body (2) and a respective inner compartment (36) accessible from the first inner face (7) and suitable to be arranged upside down on the inner compartment (36) of the other container body (2) to close the box (35) between the two inner compartments (36) when the two first inner faces (7) are coupled together. The box (35) consists of two half-boxes (37; 52), each of which has at least one closed cavity for containing a eutectic solution and at least one cup seat (38; 53) for the article (34). The half-boxes (37; 52) can be positioned on top of each other so that the cup seat (38; 53) of one half-box (37; 52) is arranged upside down on the cup seat (38; 53) of the other half-box (37; 52) to close the article (34) between the two cup seats (38; 53).
B65D 77/04 - Articles or materials enclosed in two or more containers disposed one within another
B65D 21/02 - Containers specially shaped, or provided with fittings or attachments, to facilitate nesting, stacking, or joining together
G21F 5/015 - Transportable or portable shielded containers for storing radioactive sources, e.g. source carriers for irradiation unitsRadioisotope containers
3.
UNIT FOR HANDLING A CONTAINER FOR THE PRODUCTION OF RADIOISOTOPES
A unit for handling a container for a solid target material having a support body and a lid screwed onto the support body and for dissolving the solid target material in the container, the unit comprising a shielded isolator and within it: a work surface having a transfer port for the container; an unscrewing and screwing station having a rotating support mounted on the work surface for supporting the container and rotating the support body and a gripping device for holding the lid while the rotating support rotates for unscrewing or screwing the lid; a dissolution station for feeding a dissolving solution in the container with the purpose of dissolving the solid target material; and a handling device for moving the container between the transfer port and the unscrewing and screwing station and between the latter and the dissolution station.
G21G 1/10 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes outside of nuclear reactors or particle accelerators by bombardment with electrically-charged particles
G21G 1/00 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes
G21G 4/08 - Radioactive sources other than neutron sources characterised by constructional features specially adapted for medical applications
4.
IRRADIATION STATION FOR A RADIOISOTOPE PRODUCTION SYSTEM
An irradiation station for producing a radioisotope, having a cyclotron for emitting a proton beam against a solid target material placed in a container and a cooling system for cooling the container. The container has a wall for supporting the solid target material and a cavity, which borders the wall and has an opening transverse to the axis of the container. The cooling system has a connection head which is couplable to the opening for circulating a cooling fluid in the cavity and comprises a flow diverter, a tip protruding from a hole of the flow diverter and movable along the hole against the action of a spring in contact with the tip, and an electrical connector in contact with the spring. When the connection head is coupled to the opening the flow diverter enters the cavity coaxially with the container and the tip presses against the wall.
G21G 1/10 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes outside of nuclear reactors or particle accelerators by bombardment with electrically-charged particles
5.
METHOD FOR FILLING A SINGLE-DOSE CARTRIDGE FOR ADMINISTERING A LIQUID RADIOPHARMACEUTICAL
A method for filling a cartridge for the administration of a radiopharmaceutical, the cartridge (1) comprising : a cylindrical container (2) that has, at its two longitudinal ends, a first and a second opening (3, 4); a stopper (5), which is initially positioned near the first opening (3) and is hermetically movable inside the container (2); and a cap (6) to close the second opening (4). A filling position for the stopper (5) along the container (2) is calculated based on the desired dose of radiopharmaceutical and an additional safety displacement (ΔS). The stopper (5) is moved towards the second opening (4) to the filling position, the desired dose of radiopharmaceutical is introduced into the container (2) using a needle (13) facing the second opening (4), the stopper (5) is moved towards the second opening (4) by an amount equal to the additional displacement (ΔS), and the second opening (4) is closed with the cap (6).
B65B 7/28 - Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers
G01B 11/22 - Measuring arrangements characterised by the use of optical techniques for measuring depth
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
B65B 3/06 - Methods of, or means for, filling the material into the containers or receptacles by gravity flow
B65B 3/30 - Methods or devices for controlling the quantity of the material fed or filled by volumetric measurement
B65B 57/04 - Automatic control, checking, warning or safety devices responsive to absence, presence, abnormal feed, or misplacement of binding or wrapping material, containers, or packages and operating to control, or to stop, the feed of such material, containers, or packages
Apparatus for crushing an ampoule made of glassy material and containing a radioisotope, the apparatus (1) having a deformable tube (7) suitable for receiving the ampoule (2), a clamping device (13) for creating a bottleneck in the tube (7) so as to stop the ampoule (2) in the tube (7) in a crushing position, and a crushing device (20) for crushing the ampoule (2) at the crushing position. The crushing device (20) has a sonotrode (21), an actuator (22) for moving the sonotrode (21) to and from a contact position, wherein the sonotrode (21) is in contact with a portion of the outer surface of the tube (7) such that a corresponding portion of the inner surface of the tube (7) contacts the ampoule (2) at the cushing position, and an ultrasonic generator (23) to apply vibrations at ultrasonic frequencies to the sonotrode (21) when the latter is in the contact position so as to crush the ampoule (2) inside the tube (7).
B02C 1/00 - Crushing or disintegrating by reciprocating members
B02C 19/00 - Other disintegrating devices or methods
B06B 3/00 - Processes or apparatus specially adapted for transmitting mechanical vibrations of infrasonic, sonic or ultrasonic frequency
B23K 20/10 - Non-electric welding by applying impact or other pressure, with or without the application of heat, e.g. cladding or plating making use of vibrations, e.g. ultrasonic welding
B67B 7/92 - Hand- or power-operated devices for opening closed containers by breaking, e.g. for ampoules
B02C 19/18 - Use of auxiliary physical effects, e.g. ultrasonics, irradiation, for disintegrating
8.
STORAGE FOR CONTAINERS FOR A SOLID TARGET MATERIAL FOR A RADIOISOTOPE PRODUCTION SYSTEM
A storage for containers for a solid target material for a radioisotope production system, the storage comprising: a container body, the bottom of which has a first opening for the passage of a container; a shelf, which is movable to and from a position in which the shelf obstructs the first opening; a lid, which closes the container body and comprises a second opening coaxial to the first opening for the passage of a container; and a drum, which is coaxially housed in the container body, comprises a plurality of seats to hold respective standing containers and is adapted to rotate to position each seat between a transfer position, in which the seat is aligned with the second opening to receive a container when the shelf obstructs the first opening or to allow direct passage of a container between the first and the second opening, and a plurality of storage positions, in each of which the seat is not facing the second opening.
G21G 1/10 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes outside of nuclear reactors or particle accelerators by bombardment with electrically-charged particles
9.
CONTAINER FOR A SOLID TARGET MATERIAL AND CORRESPONDING IRRADIATION STATION FOR THE PRODUCTION OF A RADIOISOTOPE
A container for a solid target material and a radioisotope produced by proton beam irradiation of the solid target material, the container having: a well, which is suited to support on its own bottom wall a portion of solid target material; a support body, which extends along a longitudinal axis and has a seat for housing the well in such a way that the bottom wall is arranged transversely to the longitudinal axis; and a lid, which comprises a central portion having a degrader foil for degrading the proton beam and can be fitted on the support body so that the central portion is arranged in the well to retain the portion of solid target material on the bottom wall and that the degrader foil is arranged above the portion of solid target material.
G21F 5/015 - Transportable or portable shielded containers for storing radioactive sources, e.g. source carriers for irradiation unitsRadioisotope containers
G21F 5/12 - Closures for containersSealing arrangements
G21K 5/04 - Irradiation devices with beam-forming means
G21K 5/08 - Holders for targets or for objects to be irradiated
H05H 6/00 - Targets for producing nuclear reactions
10.
CONTAINER FOR AN ELECTRODEPOSITED SOLID TARGET MATERIAL FOR THE PRODUCTION OF A RADIOISOTOPE
A container for a solid target material and a radioisotope produced by proton beam irradiation of the solid target material, the container having a support body, which extends according to a longitudinal axis of the container and has a cylindrical portion having a first longitudinal end defined by a planar face, transverse to the longitudinal axis and suitable to receive, by electrodeposition, a portion of solid target material, and a cup cap, which is fitted coaxially onto the support body to cover it and has a bottom traversable by the proton beam and transverse to the longitudinal axis to define, together with the face, an interspace to contain the portion of solid target material and the radioisotope subsequently produced.
G21G 1/10 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes outside of nuclear reactors or particle accelerators by bombardment with electrically-charged particles
G21K 5/08 - Holders for targets or for objects to be irradiated
11.
SINGLE-USE SHIELDED CONTAINER FOR A VIAL CONTAINING A DOSE OF RADIOPHARMACEUTICAL
A single-use shielded container for a vial containing a dose of radiopharmaceutical, the single-use shielded container (1) having a lower part (2), which is cup-shaped to accommodate the vial (3) and includes a first shielding body (5) in the shape of a cup; an upper part (4), which acts as a lid to close the lower part (2) and comprises a second shielding body (7); a first RFID tag (25) arranged in the lower part (2); and a second RFID tag (26) arranged in the upper part (4). The two RFID tags (25, 26) incorporate two respective identification codes.
G21F 5/015 - Transportable or portable shielded containers for storing radioactive sources, e.g. source carriers for irradiation unitsRadioisotope containers
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
12.
SYSTEM AND METHOD FOR RAPID AND STERILE TRANSFER OF A VIAL INTO AN ISOLATOR
A system for the rapid and sterile transfer of a vial into a pharmaceutical isolator having a working chamber, the system having: a first chamber having a first opening for insertion of the vial; a second chamber communicating with the first chamber through a second opening and having a third opening for the exit of the vial; a support structure enclosing the first and second chambers and mountable in a wall of the working chamber so that the first opening faces an outer environment and the third opening faces the working chamber; a first transfer component movable in the first chamber between two positions aligned to the first opening and, respectively, to the second opening; a second component movable in the second chamber between two positions aligned to the second opening and, respectively, to the third opening; a ventilation apparatus for generating an air flow in the first chamber; and a sterilisation apparatus for circulating vaporised hydrogen peroxide in the second chamber.
An isolator (1) for sterile applications, having a work chamber (2), a laminar air flow generation system (5) communicating with a ceiling (9) of the work chamber (2), an interspace (11) for the air return, which is external to the work chamber and communicates with a lower portion (12) of the work chamber (2) through a return opening (13) and with an upper portion (15) of the work chamber (2) through a delivery opening (16), a movable hatch (17) applied to the delivery opening (16), and a decontaminating substance supply system (21) for feeding nebulized hydrogen peroxide. The decontaminating substance supply system (21) has a nebulizer nozzle (22) arranged in the interspace (11) so that the nebulized hydrogen peroxide circulates in the work chamber (2) when the hatch (17) is open and the laminar air flow generation system (5) is switched off.
A modular container (1) for carrying at least one article (34), including a radiopharmaceutical, comprising two container bodies (2) couplable to each other and a rigid casing (3) formed by two covers (4) connected to each other by means of two connector elements (5) to hold the two container bodies (2) coupled together. Each container body (2) has a base portion (6), which has an inner face (7) couplable to the inner face (7) of the other container body (2), a bottom face (8) parallel to the inner face (7), two lateral outer faces (9, 10) parallel to each other and orthogonal to the inner face (7) and at least one seat (11) accessible from the inner face (7) and capable of being placed upside down on the seat (11) of the other container body (2) to close the article (34) between the two seats (11) when the two inner faces (7) are coupled together. Each cover (4) has a first portion (19) suitable for being placed on the bottom face (8) of one container body (2) and a second portion (20) orthogonal to the first portion (19) and suitable for being placed on the same lateral outer face (9, 10) of both container bodies (2).
G21F 5/015 - Transportable or portable shielded containers for storing radioactive sources, e.g. source carriers for irradiation unitsRadioisotope containers
A system for the production of a radioisotope comprising a container (1), which has a planar face (4) on which a portion of solid target material (M) is present having an elliptical shape, an irradiation station (35) for emitting a proton beam (B) against the portion of solid target material (M) in the container (1) and a transfer system (37) for transferring the container (1) to the irradiation station (35). The irradiation station (35) has an annular seat (39), which is suitable for coaxially receiving the container (1) from the side of the planar face (4) and is oriented obliquely with respect to the proton beam (B) in such a way that a section (S) of the proton beam (B) along a plane of the annular seat (39) is elliptical. The transfer system (37) comprises a housing (42) for the container (1), a rotation assembly (43) for rotating the container (1) within the housing (42) in order to orient the elliptical shape of the solid target material portion (M) as the elliptical shape of the proton beam section (B), and a handling assembly (45) for grasping the container (1) from the side opposite the planar face (4) and transferring it from the housing (42) to the annular seat (39).
G21G 1/10 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes outside of nuclear reactors or particle accelerators by bombardment with electrically-charged particles
G21F 5/015 - Transportable or portable shielded containers for storing radioactive sources, e.g. source carriers for irradiation unitsRadioisotope containers
16.
GRIPPING HEAD FOR GRIPPING A CONTAINER FOR A SOLID TARGET MATERIAL FOR A UNIT SUITABLE FOR HANDLING THE CONTAINER AND DISSOLVING THE SOLID TARGET MATERIAL IN THE CONTAINER
Gripping head (52) for gripping a container (1) for a solid target material in a unit ((3333)) for handling the container (1) and dissolving the solid target material in the container (1), which has a support body (5) for the solid target material, The gripping head (52) has a housing cavity (67), which has an access opening (68) for inserting the container (1) into the housing cavity (67), at least oonnee inflatable element (69), which is arranged in the housing cavity (67) in such a way as to define, when inflated, an obstruction capable of retaining, by interference, the support body (5) in the housing cavity (67), and a first conduit (71), which is connectable with a compressed air generator (70) for inflating the inflatable element (69).
G21F 5/14 - Devices for handling containers or shipping-casks, e.g. transporting devices
G21G 1/00 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes
17.
SYSTEM FOR THE TRANSFER AND STORING OF RADIOACTIVE WASTE FOR A SHIELDED CELL
A system for transferring and storing radioactive waste for a shielded cell comprising a duct (3) for discharging radioactive waste, the system (1) having: a first frame (4) which is attachable below the duct (3); a cylindrical shielded container (8) for radioactive waste, provided with a collar (20); a rapid transfer port having an alpha port (18) fixable on the duct (3) and a beta port (19) closing the container (8); a second frame (10) to support the container (8) through the collar (20), and movable relative to the first frame (4) towards an alignment position, wherein the container (8) is coaxial to the discharge duct (3); a shielded cover (21) movably mounted on the collar (20) to cover and uncover the beta port (19); a lifter (49) to lift the container (8) to a raised position, wherein the beta port (19) rests on the alpha port (18); and a rotating key (52) mounted on the first frame (4) to rotate coaxially to the duct (3), engageable by an outer portion (32) of the container (8) in the raised position to allow coupling between the beta port (19) and the alpha port (18).
A unit (33) for handling a container (1) for a solid target material having a support body (5) and a lid (8) screwed onto the support body (5) and for dissolving the solid target material in the container (1), the unit (33) comprising a shielded isolator (36) and within it: a work surface (37) having a transfer port (38) for the container (1); an unscrewing and screwing station (39) having a rotating support (42) mounted on the work surface (37) for supporting the container (1) and rotating the support body (5) and a gripping device (43) for holding the lid (8) while the rotating support (42) rotates for unscrewing or screwing the lid (8); a dissolution station (40) for feeding a dissolving solution in the container (1) with the purpose of dissolving the solid target material; and a handling device (41) for moving the container (1) between the transfer port (38) and the unscrewing and screwing station (39) and between the latter and the dissolution station (40).
G21F 5/015 - Transportable or portable shielded containers for storing radioactive sources, e.g. source carriers for irradiation unitsRadioisotope containers
G21F 5/14 - Devices for handling containers or shipping-casks, e.g. transporting devices
G21G 1/10 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes outside of nuclear reactors or particle accelerators by bombardment with electrically-charged particles
19.
IRRADIATION STATION FOR A RADIOISOTOPE PRODUCTION SYSTEM
An irradiation station for producing a radioisotope, having a cyclotron (32) for emitting a proton beam (B) against a solid target material (M) placed in a container (1) and a cooling system (33) for cooling the container (1). The container (1) has a wall (4) for supporting the solid target material (M) and a cavity (12), which borders the wall (4) and has an opening (14) transverse to the axis of the container (1). The cooling system (33) has a connection head (34) which is couplable to the opening (14) for circulating a cooling fluid in the cavity (12) and comprises a flow diverter (37), a tip (47) protruding from a hole (46) of the flow diverter (37) and movable along the hole (46) against the action of a spring (48) in contact with the tip (47), and an electrical connector (52) in contact with the spring (48). When the connection head (34) is coupled to the opening (14) the flow diverter (37) enters the cavity (12) coaxially with the container (1) and the tip (47) presses against the wall (4).
G21G 1/10 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes outside of nuclear reactors or particle accelerators by bombardment with electrically-charged particles
H05H 6/00 - Targets for producing nuclear reactions
20.
STORAGE FOR CONTAINERS FOR A SOLID TARGET MATERIAL FOR A RADIOISOTOPE PRODUCTION SYSTEM
A storage for containers for a solid target material for a radioisotope production system, the storage (23) comprising: a container body (36), the bottom of which has a first opening (47) for the passage of a container (2); a shelf (52), which is movable to and from a position in which the shelf (52) obstructs the first opening (47); a lid (39), which closes the container body (36) and comprises a second opening (49) coaxial to the first opening (47) for the passage of a container (2); and a drum (40), which is coaxially housed in the container body (36), comprises a plurality of seats (41) to hold respective standing containers and is adapted to rotate to position each seat (41) between a transfer position, in which the seat (41) is aligned with the second opening (49) to receive a container (2) when the shelf (52) obstructs the first opening (47) or to allow direct passage of a container (2) between the first and the second opening (47, 49), and a plurality of storage positions, in each of which the seat (41) is not facing the second opening (49).
A container for a solid target material and a radioisotope produced by proton beam irradiation of the solid target material, the container (1) having : a well (3), which is suited to support on its own bottom wall (4) a portion of solid target material (M1; M2); a support body (5), which extends along a longitudinal axis (2) and has a seat (7) for housing the well (3) in such a way that the bottom wall (4) is arranged transversely to the longitudinal axis (2); and a lid (8), which comprises a central portion (9) having a degrader foil (10) for degrading the proton beam and can be fitted on the support body (5) so that the central portion (9) is arranged in the well (3) to retain the portion of solid target material (M1; M2) on the bottom wall (4) and that the degrader foil (10) is arranged above the portion of solid target material (M1; M2).
G21F 5/015 - Transportable or portable shielded containers for storing radioactive sources, e.g. source carriers for irradiation unitsRadioisotope containers
G21G 1/10 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes outside of nuclear reactors or particle accelerators by bombardment with electrically-charged particles
H05H 6/00 - Targets for producing nuclear reactions
22.
CONTAINER FOR AN ELECTRODEPOSITED SOLID TARGET MATERIAL FOR THE PRODUCTION OF A RADIOISOTOPE
A container for a solid target material and a radioisotope produced by proton beam irradiation of the solid target material, the container (1) having a support body (3), which extends according to a longitudinal axis (2) of the container (1) and has a cylindrical portion (11) having a first longitudinal end defined by a planar face (4), transverse to the longitudinal axis (2) and suitable to receive, by electrodeposition, a portion of solid target material (M), and a cup cap (6), which is fitted coaxially onto the support body (3) to cover it and has a bottom (15) traversable by the proton beam and transverse to the longitudinal axis ((22)) to define, together with the face (4), an interspace (25) to contain the portion of solid target material (M) and the radioisotope subsequently produced.
G21G 1/10 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes outside of nuclear reactors or particle accelerators by bombardment with electrically-charged particles
H05H 6/00 - Targets for producing nuclear reactions
23.
SYSTEM AND METHOD FOR RAPID AND STERILE TRANSFER OF A VIAL INTO AN ISOLATOR
A system for the rapid and sterile transfer of a vial into a pharmaceutical isolator having a working chamber (3), the system (1) having: a first chamber (6) having a first opening (7) for insertion of the vial (2); a second chamber (9) communicating with the first chamber (6) through a second opening (10) and having a third opening (11) for the exit of the vial (2); a support structure (13) enclosing the first and second chambers (6, 9) and mountable in a wall (4) of the working chamber (3) so that the first opening (7) faces an outer environment (5) and the third opening (11) faces the working chamber (3); a first transfer component (15) movable in the first chamber (6) between two positions aligned to the first opening (7) and, respectively, to the second opening (10); a second component (16) movable in the second chamber (9) between two positions aligned to the second opening (7) and, respectively, to the third opening (11); a ventilation apparatus (17) for generating an air flow in the first chamber (6); and a sterilisation apparatus (18) for circulating vaporised hydrogen peroxide in the second chamber (9).
An apparatus for removing a flip-off cap from a bottle for pharmaceutical substances, which enables automating the removal process in a pharmaceutical substance handling line and, at the same time, may be easy and inexpensive to manufacture. In an example the apparatus comprises a removal station in which a cap is removed from the bottle.
B65B 69/00 - Unpacking of articles or materials, not otherwise provided for
B67B 7/14 - Hand- or power-operated devices for opening closed containers for removing tightly-fitting lids or covers, e.g. of shoe-polish tins, by gripping and rotating
25.
Plant and method to continuously decontaminate rigid containers
A plant to continuously decontaminate containers, comprising: a decontamination chamber having a tray having through openings and a feeding grid to feed at least one row of containers, which are aligned according to a first direction, along the tray, in a second direction, which is transverse to the first direction; a vaporized hydrogen peroxide generator to generate a gaseous mixture comprising air and vaporized hydrogen peroxide; a forced ventilation system to generate, in the chamber, a first flow of gaseous mixture that hits the row of containers from above; and a dispenser system arranged under the tray to generate a second flow of gaseous mixture, which hits the row of containers from below, through the through openings. The feeding grid comprises pushing members uniformly equidistant to each other along the second direction so that any pair of pushing members adjacent to each other can accommodate a row of containers.
A modular incubator comprising a housing structure divided into cells and having several incubator modules, each of which can be housed, in a removable manner, in a relative cell and is provided with an incubation chamber to incubate microbiological or cellular cultures. Each cell has a first group of connectors and each incubator module has a second group of connectors, each of which can be coupled to a corresponding connector of the first group of connectors of the relative cell when the incubator module is housed in said cell. The first group of connectors has at least one pneumatic connector communicating with at least one source of aeriform substance, and the second group of connectors has a corresponding pneumatic connector communicating with the relative incubation chamber to allow the aeriform substance to be introduced into the incubation chamber.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
11 - Environmental control apparatus
42 - Scientific, technological and industrial services, research and design
Goods & Services
Pharmacy processing industrial machines; dust removing
installations for cleaning purposes; dust separators;
machinery to produce tablets; machine for dosing products;
filling machines. Isolator and glove boxes; weighing apparatus and
instruments; load cells; radiation protection systems;
sensors, software and electronic control units for the
control and management of the pharmacy processing industrial
machines, machinery to produce tablets, machines for dosing
products, filling machines, apparatus for dosing humans by
injection and sterilizers. Electromedical instruments, namely apparatus for dosing
humans by injection. Sterilizers. Quality control; product quality evaluation; certificate of
quality system; quality control testing of pharmaceutical
products for certification purposes.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
11 - Environmental control apparatus
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Pharmaceutical processing machines, namely, machines for dosing and manufacturing tablets, capsules and liquid medicaments; dust collecting machines for chemical and pharmaceutical processing.
(2) Biological, chemical and radiopharmaceutical safety cabinets for laboratory use; weighing scales for medical use; electronic load modules; radiation shields for radiopharmaceutical products; electric motor control units comprising electronic sensors and related software for pharmaceutical processing machines, namely, machines for dosing and manufacturing tablets and liquid medicaments and injection instruments without needles, namely, injection dosage dispensers
(3) Injection instruments without needles, namely, injection dosage dispensers.
(4) Sterilizers for medical use. (1) Quality control testing of pharmaceutical products for certification purposes
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
11 - Environmental control apparatus
42 - Scientific, technological and industrial services, research and design
Goods & Services
Pharmacy processing industrial machines; machine for dispensing vial and syringes; filling machines for filling IV bags Laboratory equipment, namely, isolation glove boxes for handling air sensitive compounds and toxic substances; weighing apparatus and instruments; force measurement products, namely, load cells; radiation protection systems comprised of isolation shielded glove boxes, and control systems comprised of computer hardware and computer peripherals and downloadable industrial process control software; electric sensors, downloadable software and electronic control units for the control and management of the pharmacy processing industrial machines, machinery to produce tablets, machines for dosing products, filling machines, apparatus for dosing humans by injection and sterilizers Electromedical instruments, namely, automatic medical apparatus for dosing humans by injection Sterilizers Quality control for others; product quality evaluation; certificate of quality system, namely, performing quality control for others; product quality control testing of pharmaceutical products for certification purposes
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
11 - Environmental control apparatus
42 - Scientific, technological and industrial services, research and design
Goods & Services
Machines and machine tools for use in the pharmaceutical field, machines for fractionating toxic powders, tablet presses, Product dosing machines, Product filling machines. Safety isolators; Weight control devices; Load cells; Radioprotection systems for medical, research and industrial applications; Electronic sensors, components, electrical parts and controllers and switchboards for the aforesaid machines and for those included in class 10 and 11. Electro-medical apparatus and instruments; Galvanic therapeutic appliances; Protection devices against rays, for medical purposes; Automatic medical apparatus for dosing by injection. Sterilisers; Steamers for chemical processing; Decontamination chambers; Sterilization, disinfection and decontamination equipment. Security certification activities of machines and installations designed for pharmaceutical applications.
A modular incubator comprising a housing structure divided into cells and having several incubator modules, each of which can be housed, in a removable manner, in a relative cell and is provided with an incubation chamber to incubate microbiological or cellular cultures. Each cell has a first group of connectors and each incubator module has a second group of connectors, each of which can be coupled to a corresponding connector of the first group of connectors of the relative cell when the incubator module is housed in the cell. The first group of connectors has at least one pneumatic connector communicating with at least one source of aeriform substance, and the second group of connectors has a corresponding pneumatic connector communicating with the relative incubation chamber to allow the aeriform substance to be introduced into the incubation chamber.
A container (100) for holding, on the inside, at least one receptacle (50; 80) containing, in turn, dangerous waste. The container (100) comprises a lower shell (20), which is closed by an upper lid (30), which is fixed to it through fixing devices (40). The container (100) is characterized in that it is shaped, in its plan view, as a lobed polygon having a plurality of curvilinear sides (L1), (L2), (L3), (L4), (L5), (L6). Each curvilinear side (L1), (L2), (L3), (L4), (L5), (L6) comprises at least three respective curved portions (60A, 60B, 60C), wherein the central curved portion (60A) has a bend radius (R1), whose centre (C1) of curvature is opposite to the centre (C2) of curvature (with radius (R2)) of the first lateral curved portion (60B) and, respectively, is opposite to the centre (C3) of curvature (with radius (R3)) of the second lateral curved portion (60C).
CARTRIDGE FOR A RADIOPHARMACEUTICAL, SHIELDED CONTAINER FOR SAID CARTRIDGE AND CORRESPONDING APPARATUS FOR INFUSION OF A RADIOPHARMACEUTICAL DOSE TO A PATIENT
An apparatus for administration by infusion of radiopharmaceuticals to a patient, having a cartridge (1) for a radiopharmaceutical that has two perforable diaphragms (7, 8), a shielded container (22) containing the cartridge and having two openings (35, 36) in positions corresponding to the two diaphragms (7, 8), a frame (51) for supporting two bags of saline solution (54, 55) and the shielded container (22), a first tube (62) connected to one bag (55) and having a needle (63) to be inserted, through one of the two openings (35), into a first diaphragm (7) so as to supply saline solution (54) to the cartridge (1), a second tube (64) with a needle (65) to be inserted, through the other opening (36), into the other diaphragm (8) for supplying a flow of radiopharmaceutical (FR), a dual-inlet connector (66) connected to the second tube (64) and, via a third tube (61), to the other bag (54) for supplying a mixture (MX) of saline solution and radiopharmaceutical, and a drip chamber (59) connected to the outlet of the dual-inlet connector (66).
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
37.
Method and plant for filling a bottle with a radioactive fluid-based mixture
B65B 3/14 - Methods of, or means for, filling the material into the containers or receptacles by application of pressure to material pneumatically
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
A61K 51/00 - Preparations containing radioactive substances for use in therapy or testing in vivo
G21F 5/015 - Transportable or portable shielded containers for storing radioactive sources, e.g. source carriers for irradiation unitsRadioisotope containers
G21G 1/00 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes
38.
KIT FOR DOSING AND DELIVERING OF RADIOACTIVE DRUGS
A kit (1) for dosing and delivering radioactive drugs comprising a bulk (2) in which the radioactive drug to be dosed is totally transferred, an ionising chamber (3) in which the bulk (2) is housed and which is adapted to count the radioactivity contained in the bulk (2), weighing means (4) adapted to determine the weight of the bulk (2), a first syringe (5) adapted to perform the dosing operations, a second syringe (6) adapted to control the delivery of the radioactive drug to the patient, a bottle of physiological solution (7), a plurality of three-way valves (8) connected in series to one another and adapted to control the movements of the physiological solution and of the radioactive drug and a plurality of transport lines (9).
G21G 1/00 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes
A61K 51/12 - Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes
3 with concentration from 0.5 to 2.5 M, a pH buffering operation, and a recirculation operation, in which the solution obtained above is circulated at a rate from 0.5 to 3 within an electrolytic cell during the current output within the cell itself; the electrodeposition of the target to be irradiated occurs within the electrolytic cell during the recirculation operation.
A system for automatic production of radioisotopes includes an irradiation unit connectable to a cyclotron and having an electrolytic cell; a purification unit for purifying the radioisotope formed in the irradiation unit; two conduits for transferring an irradiated and electrodissolved target from the irradiation unit to the purification unit; and a central control unit for controlling both the operating units and the transfer means. The method for producing radioisotopes is such that the target carrier is not dissolved together with the irradiated target.
G21G 1/00 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes
G21G 1/10 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes outside of nuclear reactors or particle accelerators by bombardment with electrically-charged particles
