Acubens

France

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G01N 33/483 - Physical analysis of biological material 1
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METHOD FOR EVALUATING, VIA BIODOSIMETRY, THE IRRADIATION DOSE RECEIVED BY A PERSON SUBJECTED TO IONIZING RADIATION

      
Application Number FR2014051136
Publication Number 2014/184498
Status In Force
Filing Date 2014-05-15
Publication Date 2014-11-20
Owner ACUBENS (France)
Inventor
  • Jukic Ivana
  • Schellenberg Amélie
  • Delic Jozo
  • Tupinier Arnaud
  • Paget Vincent
  • Fedor Yohann
  • Morat Luc
  • Ugolin Nicolas
  • Flack Caroline
  • Chevillard Sylvie
  • Lefevre Emilie

Abstract

The invention relates to a method for evaluating, via biodosimetry, the irradiation dose received by a person subjected to ionizing radiation. Said method comprises: a) sampling, in at least one area of the body of the person, the follicles or bulbs of head and/or body hair of the person; b) extracting proteins from cells of said sampled hair bulbs or follicles, wherein said proteins, including proteins from the ATM system, are subjected to phosphorylation and/or acetylation induced by ionizing radiation; and c) analyzing at least two types of extracted proteins and interpreting the analysis results in order to determine the irradiation dose in the or each sampling area.

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