Abstract

Fagopyrum dibotyo nutraceuticals and methods of their use are provided. The disclosed F. dibotyo nutraceuticals are useful to improve or increase liver function and to treat liver diseases, especially those caused by viral hepatitis. In some embodiments, the F. dibotyo nutraceuticals also contain supplementary botanical extracts to confer additional health benefits.

IPC Classes  ?

• A61K 36/70 - Polygonaceae (Buckwheat family), e.g. spineflower or dock
• A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
• A61K 31/353 - 3,4-Dihydrobenzopyrans, e.g. chroman, catechin
• A61K 36/076 - Poria
• A61K 36/28 - Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
• A61K 36/282 - Artemisia, e.g. wormwood or sagebrush
• A61K 36/288 - Taraxacum (dandelion)
• A61K 36/31 - Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
• A61K 36/36 - Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
• A61K 36/48 - Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
• A61K 36/536 - Prunella or Brunella (selfheal)
• A61K 36/68 - Plantaginaceae (Plantain Family)
• A61K 36/82 - Theaceae (Tea family), e.g. camellia
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61P 31/14 - Antivirals for RNA viruses

Abstract

Nutraceutical compositions and methods of their use in treating Caliciviridae family viruses are provided. The viruses can be norovirus or sapovirus. An exemplary nutraceutical composition includes Fagopyrum dibotyo extract. Another nutraceutical composition for treating viral gastroenteritis includes 5, 7, 3′, 4′-tetrahydroxyflavan-3-ol C4-C8 dimers, quercetin, rutin, or a combination thereof. The nutraceutical compositions inhibit or reduce entry of Caliciviridae family viruses into intestinal epithelial cells of the subject.

IPC Classes  ?

• A61K 36/70 - Polygonaceae (Buckwheat family), e.g. spineflower or dock
• A61K 36/28 - Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
• A61K 36/482 - Cassia, e.g. golden shower tree
• A61K 36/536 - Prunella or Brunella (selfheal)
• A61K 36/634 - Forsythia
• A61K 36/31 - Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
• A61K 36/282 - Artemisia, e.g. wormwood or sagebrush
• A61K 36/36 - Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
• A61K 36/076 - Poria
• A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
• A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
• A61K 31/58 - Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
• A61P 31/14 - Antivirals for RNA viruses

Abstract

CaliciviridaeFagopyrum dibotyo 48CaliciviridaeCaliciviridae family viruses into intestinal epithelial cells of the subject.

IPC Classes  ?

• A61K 31/353 - 3,4-Dihydrobenzopyrans, e.g. chroman, catechin
• A61K 36/70 - Polygonaceae (Buckwheat family), e.g. spineflower or dock
• A61P 31/12 - Antivirals
• A61P 31/14 - Antivirals for RNA viruses

Abstract

Fagopyrum dibotyoF. dibotyoF. dibotyo F. dibotyo nutraceuticals also contain supplementary botanical extracts to confer additional health benefits.

IPC Classes  ?

• A61K 36/70 - Polygonaceae (Buckwheat family), e.g. spineflower or dock
• A61K 8/49 - Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
• A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
• A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics