A medicament dispenser (1) comprising: a body (10) comprising an inlet (11) configured to interface with a syringe (70) and an outlet (15) configured to interface with a needle (60); a dosing chamber (20) within said body comprising a dosing chamber inlet (21) fluidly connected to the inlet (11) of the body (10) and a dosing chamber outlet (22) fluidly connected to the outlet (15) of the body (10), the dosing chamber (20) being configured to contain a fixed volume of medicament (75) when full; and a piston (40) configured to be movable within the dosing chamber (20) to deliver the fixed volume of medicament (75) out of the outlet (15) of the body (10).
A61M 5/36 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests with means for eliminating or preventing injection or infusion of air into body
A61M 5/315 - Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod; Appliances on the rod for facilitating dosing
05 - Pharmaceutical, veterinary and sanitary products
40 - Treatment of materials; recycling, air and water treatment,
10 - Medical apparatus and instruments
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Pharmaceutical preparations and substances for the treatment of infectious, viral, bacterial, metabolic, endocrine, exocrine, muscular, skeletal, cardiovascular, respiratory, reproductive, digestive, excretory, renal, oncological, hepatological, ophthalmic, respiratory, neurological, gastrointestinal, lymphatic, integumentary, nervous, hormonal, dermatological, psychiatric and immunological related diseases and disorders; Pharmaceutical products, namely, respiratory drugs for treating respiratory diseases and asthma; respiratory vaccines Custom manufacture of medical devices for others; custom manufacture of medical devices to the order and specification of others, namely, inhalers and drug delivery devices sold empty, and pharmaceuticals; custom manufacture of components, parts and fittings for all the aforesaid products; management of product lifecycles for others, in the nature of custom manufacturing of medical devices to the order and specification of others, namely, inhalers and drug delivery devices sold empty, and pharmaceuticals; custom manufacturing of injection molded parts for others; custom manufacture of active pharmaceutical ingredients for others; custom manufacture of pharmaceuticals for others Drug delivery devices sold empty, namely, nasal inhalers for medical purposes, sold empty; pressurised metered dose inhalers (pMDI) for medical purposes, sold empty; nasal sprays for medical purposes; soft mist inhalers for medical purposes, sold empty; parts and fittings for all the aforesaid goods Provision of training, teaching and educational services in the nature of workshops, lectures, classes and tutorials, all in the field of manufacturing, engineering, chemistry and pharmaceuticals; training services in the field of injection molding manufacturing; advisory, consultancy and information services relating to all the aforesaid Research and development of medical apparatus and instruments for others; research and development of inhalers and design of prototyping services; metrology services; Research laboratory testing and analysis services in the field of prototyping, metrology, manufacturing, engineering, chemistry, medical and pharmaceuticals; product quality testing services; quality control advisory services namely regulatory quality control advisory and management of product lifecycles for others, namely, continuing scientific research in the nature of conducting and managing clinical trials and trials of medical apparatus and instruments, inhalers and drug delivery products, pharma and medical related products and apparatus; consulting services in the field of pharmaceutical research and development; consulting services in the field of drug delivery devices; advisory, consultancy and information services relating to all the foresaid
05 - Pharmaceutical, veterinary and sanitary products
40 - Treatment of materials; recycling, air and water treatment,
10 - Medical apparatus and instruments
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Pharmaceutical preparations and substances for the treatment of infectious, viral, bacterial, metabolic, endocrine, exocrine, muscular, skeletal, cardiovascular, respiratory, reproductive, digestive, excretory, renal, oncological, hepatological, ophthalmic, respiratory, neurological, gastrointestinal, lymphatic, integumentary, nervous, hormonal, dermatological, psychiatric and immunological related diseases and disorders; Pharmaceutical products, namely, respiratory drugs for treating respiratory diseases and asthma; respiratory vaccines Custom manufacture of medical devices for others; custom manufacture of medical devices to the order and specification of others, namely, inhalers and drug delivery devices sold empty, and pharmaceuticals; custom manufacture of components, parts and fittings for all the aforesaid products; management of product lifecycles for others, in the nature of custom manufacturing of medical devices to the order and specification of others, namely, inhalers and drug delivery devices sold empty, and pharmaceuticals; custom manufacturing of injection molded parts for others; custom manufacture of active pharmaceutical ingredients for others; custom manufacture of pharmaceuticals for others Drug delivery devices sold empty, namely, nasal inhalers for medical purposes, sold empty; pressurised metered dose inhalers (pMDI) for medical purposes, sold empty; nasal sprays for medical purposes; soft mist inhalers for medical purposes, sold empty; parts and fittings for all the aforesaid goods Provision of training, teaching and educational services in the nature of workshops, lectures, classes and tutorials, all in the field of manufacturing, engineering, chemistry and pharmaceuticals; training services in the field of injection molding manufacturing; advisory, consultancy and information services relating to all the aforesaid Research and development of medical apparatus and instruments for others; research and development of inhalers and design of prototyping services; metrology services; Research laboratory testing and analysis services in the field of prototyping, metrology, manufacturing, engineering, chemistry, medical and pharmaceuticals; product quality testing services; quality control advisory services namely regulatory quality control advisory and management of product lifecycles for others, namely, continuing scientific research in the nature of conducting and managing clinical trials and trials of medical apparatus and instruments, inhalers and drug delivery products, pharma and medical related products and apparatus; consulting services in the field of pharmaceutical research and development; consulting services in the field of drug delivery devices; advisory, consultancy and information services relating to all the foresaid
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
11 - Environmental control apparatus
40 - Treatment of materials; recycling, air and water treatment,
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Pharmaceuticals and pharmaceutical preparations and substances; respiratory drugs; respiratory vaccines
(2) Drug delivery devices; inhalers; pressurised metered dose inhalers (pMDI); nasal sprays; soft mist inhalers; parts and fittings for all the aforesaid goods (1) Custom manufacture of medical devices for others; custom manufacture of medical apparatus and instruments, inhalers and drug delivery products, pharma and medical related products and apparatus; custom manufacture of components, parts and fittings for all the aforesaid products; management of product lifecycles for others, in the nature of custom manufacturing of medical apparatus and instruments, inhalers and drug delivery products, pharma and medical related products and apparatus; provision of injection moulding services; custom manufacture of active pharmaceutical ingredients for others; custom manufacture of pharmaceuticals for others; advisory, consultancy and information services relating to all the aforesaid
(2) Provision of training, teaching and educational services; training services relating to manufacturing and injection moulding; advisory, consultancy and information services relating to all the aforesaid
(3) Research and development of medical apparatus and instruments for others; research and development of inhalers and drug delivery devices for others; research and development of pharmaceuticals, pharma and medical related products and apparatus for others; prototyping services; metrology services; laboratory services relating to analytic testing; quality testing services; quality control advisory services namely regulatory quality control advisory services relating to pharmaceuticals, active pharmaceutical ingredients, medical apparatus and instruments, inhalers and drug delivery products, pharma and medical related products and apparatus; management of product lifecycles for others, in the nature of conducting and managing clinical trials and trials of medical apparatus and instruments, inhalers and drug delivery products, pharma and medical related products and apparatus; consulting services in the field of pharmaceutical research and development; consulting services in the field of drug delivery devices; advisory, consultancy and information services relating to all the aforesaid
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
11 - Environmental control apparatus
40 - Treatment of materials; recycling, air and water treatment,
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Pharmaceuticals and pharmaceutical preparations and substances; respiratory drugs; respiratory vaccines
(2) Drug delivery devices; inhalers; pressurised metered dose inhalers (pMDI); nasal sprays; soft mist inhalers; parts and fittings for all the aforesaid goods (1) Custom manufacture of medical devices for others; custom manufacture of medical apparatus and instruments, inhalers and drug delivery products, pharma and medical related products and apparatus; custom manufacture of components, parts and fittings for all the aforesaid products; management of product lifecycles for others, in the nature of custom manufacturing of medical apparatus and instruments, inhalers and drug delivery products, pharma and medical related products and apparatus; provision of injection moulding services; custom manufacture of active pharmaceutical ingredients for others; custom manufacture of pharmaceuticals for others; advisory, consultancy and information services relating to all the aforesaid
(2) Provision of training, teaching and educational services; training services relating to manufacturing and injection moulding; advisory, consultancy and information services relating to all the aforesaid
(3) Research and development of medical apparatus and instruments for others; research and development of inhalers and drug delivery devices for others; research and development of pharmaceuticals, pharma and medical related products and apparatus for others; prototyping services; metrology services; laboratory services relating to analytic testing; quality testing services; quality control advisory services namely regulatory quality control advisory services relating to pharmaceuticals, active pharmaceutical ingredients, medical apparatus and instruments, inhalers and drug delivery products, pharma and medical related products and apparatus; management of product lifecycles for others, in the nature of conducting and managing clinical trials and trials of medical apparatus and instruments, inhalers and drug delivery products, pharma and medical related products and apparatus; consulting services in the field of pharmaceutical research and development; consulting services in the field of drug delivery devices; advisory, consultancy and information services relating to all the aforesaid
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
40 - Treatment of materials; recycling, air and water treatment,
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Pharmaceuticals and pharmaceutical preparations and substances; respiratory drugs; respiratory vaccines. Drug delivery devices; inhalers; pressurised metered dose inhalers (pMDI); nasal inhalers; soft mist inhalers; parts and fittings for all the aforesaid goods. Custom manufacture of medical devices for others; custom manufacture of medical apparatus and instruments, inhalers and drug delivery products, pharma and medical related products and apparatus; custom manufacture of components, parts and fittings for all the aforesaid products; management of product lifecycles for others, in the nature of custom manufacturing of medical apparatus and instruments, inhalers and drug delivery products, pharma and medical related products and apparatus; provision of injection moulding services; custom manufacture of active pharmaceutical ingredients for others; custom manufacture of pharmaceuticals for others; advisory, consultancy and information services relating to all the aforesaid. Provision of training, teaching and educational services; training services relating to manufacturing and injection moulding; advisory, consultancy and information services relating to all the aforesaid. Research and development of medical apparatus and instruments for others; research and development of inhalers and drug delivery devices for others; research and development of pharmaceuticals, pharma and medical related products and apparatus for others; prototyping services; metrology services; laboratory services relating to analytic testing; quality testing services; quality control advisory services namely regulatory quality control advisory services relating to pharmaceuticals, active pharmaceutical ingredients, medical apparatus and instruments, inhalers and drug delivery products, pharma and medical related products and apparatus; management of product lifecycles for others, in the nature of conducting and managing clinical trials and trials of medical apparatus and instruments, inhalers and drug delivery products, pharma and medical related products and apparatus; consulting services in the field of pharmaceutical research and development; consulting services in the field of drug delivery devices; advisory, consultancy and information services relating to all the aforesaid.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
40 - Treatment of materials; recycling, air and water treatment,
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Pharmaceuticals and pharmaceutical preparations and substances; respiratory drugs; respiratory vaccines. Drug delivery devices; inhalers; pressurised metered dose inhalers (pMDI); nasal inhalers; soft mist inhalers; parts and fittings for all the aforesaid goods. Custom manufacture of medical devices for others; custom manufacture of medical apparatus and instruments, inhalers and drug delivery products, pharma and medical related products and apparatus; custom manufacture of components, parts and fittings for all the aforesaid products; management of product lifecycles for others, in the nature of custom manufacturing of medical apparatus and instruments, inhalers and drug delivery products, pharma and medical related products and apparatus; provision of injection moulding services; custom manufacture of active pharmaceutical ingredients for others; custom manufacture of pharmaceuticals for others; advisory, consultancy and information services relating to all the aforesaid. Provision of training, teaching and educational services; training services relating to manufacturing and injection moulding; advisory, consultancy and information services relating to all the aforesaid. Research and development of medical apparatus and instruments for others; research and development of inhalers and drug delivery devices for others; research and development of pharmaceuticals, pharma and medical related products and apparatus for others; prototyping services; metrology services; laboratory services relating to analytic testing; quality testing services; quality control advisory services namely regulatory quality control advisory services relating to pharmaceuticals, active pharmaceutical ingredients, medical apparatus and instruments, inhalers and drug delivery products, pharma and medical related products and apparatus; management of product lifecycles for others, in the nature of conducting and managing clinical trials and trials of medical apparatus and instruments, inhalers and drug delivery products, pharma and medical related products and apparatus; consulting services in the field of pharmaceutical research and development; consulting services in the field of drug delivery devices; advisory, consultancy and information services relating to all the aforesaid.
A pressurised dispensing container (10) comprising a container (11) for product to be dispensed, and a valve fixed to the container, wherein the container contains a propellant comprising 1,1-difluoroethane or a derivative thereof and optionally ethanol. The valve comprises a valve stem (15), a valve body (16, 18) and one or more seals (20, 21), the valve stem being slidable within the valve body, the one or more seals co-operating with the valve stem for regulating discharge of a fluid. The valve further comprises a sealing gasket (14) for sealing the valve to the dispensing container. The one or more seals (20, 21) is/are formed from (i) an elastomeric composition, preferably an elastomeric composition comprising an ethylene-propylene-diene terpolymer. The sealing gasket (14) is formed from (ii) an elastomeric composition comprising an isobutylene polymer or co-polymer thereof.
B65D 83/14 - Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
C09K 3/10 - Materials not provided for elsewhere for sealing or packing joints or covers
A medicament dispenser (1) comprising: a body (10) comprising an inlet (11) configured to interface with a syringe (70) and an outlet (15) configured to interface with a needle (60); a dosing chamber (20) within said body comprising a dosing chamber inlet (21) fluidly connected to the inlet (11) of the body (10) and a dosing chamber outlet (22) fluidly connected to the outlet (15) of the body (10), the dosing chamber (20) being configured to contain a fixed volume of medicament (75) when full; and a piston (40) configured to be movable within the dosing chamber (20) to deliver the fixed volume of medicament (75) out of the outlet (15) of the body (10).
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
A61M 5/315 - Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod; Appliances on the rod for facilitating dosing
A61M 5/36 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests with means for eliminating or preventing injection or infusion of air into body
A syringe assembly comprising a barrel for containing one or more medicaments, the barrel having a front outlet for allowing the expulsion of said one or more medicaments from the said barrel through said outlet, and a first stopper disposed in the barrel and axially moveable therein and defining a first volume in the barrel axially forwards of the first stopper and a second volume in the barrel axially rearwards of the first stopper. The first stopper has a two way valve that is moveable between a sealing configuration and an open configuration to selectively put the first volume in fluid communication with the second volume. The two way valve is moveable from the sealing configuration to the open configuration by an increase in fluid pressure in either of the first and second volumes. The syringe assembly additionally comprises a second stopper disposed in the barrel axially rearward of the first stopper and axially moveable therein, the second stopper providing a fluid tight seal at a rear end of the second volume. The syringe assembly further comprises a first plunger rod connected to the first stopper and extending axially rearwardly through the second stopper, the second stopper sealingly engaging with the first plunger rod but permitting axial sliding of the first plunger rod therethrough. The first plunger rod is axially moveable so as to axially move the first stopper and pressurise either of the first volume and second volume causing the two way valve to move into the open configuration and fluidly connect the first volume and second volume.
A pressurised dispensing container (10) comprising a container (11) for product to be dispensed, and a valve fixed to the container, wherein the container contains a propellant comprising 1,1-difluoroethane or a derivative thereof and optionally ethanol. The valve comprises a valve stem (15), a valve body (16, 18) and one or more seals (20, 21), the valve stem being slidable within the valve body, the one or more seals co-operating with the valve stem for regulating discharge of a fluid. The valve further comprises a sealing gasket (14) for sealing the valve to the dispensing container. The one or more seals (20, 21) is/are formed from (i) an elastomeric composition, preferably an elastomeric composition comprising an ethylene-propylene-diene terpolymer. The sealing gasket (14) is formed from (ii) an elastomeric composition comprising an isobutylene polymer or co-polymer thereof.
B65D 83/14 - Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
C09K 3/10 - Materials not provided for elsewhere for sealing or packing joints or covers
A pressurised dispensing container (10) comprising a container (11) for product to be dispensed, and a valve fixed to the container, wherein the container contains a propellant comprising 1,1-difluoroethane or a derivative thereof and optionally ethanol. The valve comprises a valve stem (15), a valve body (16, 18) and one or more seals (20, 21), the valve stem being slidable within the valve body, the one or more seals co-operating with the valve stem for regulating discharge of a fluid. The valve further comprises a sealing gasket (14) for sealing the valve to the dispensing container. The one or more seals (20, 21) is/are formed from (i) an elastomeric composition, preferably an elastomeric composition comprising an ethylene-propylene-diene terpolymer. The sealing gasket (14) is formed from (ii) an elastomeric composition comprising an isobutylene polymer or co-polymer thereof.
B65D 83/14 - Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
An assembly for an autoinjector device, the assembly including a syringe support for supporting a syringe by limiting forward axial movement of the syringe relative to the syringe support, and a guard element attachable to the syringe support by an attachment so that the guard element is axially restrained both axially forwardly and axially rearwardly relative to the syringe support by the attachment. Forwardly directed axial loads received by the guard element are transmitted to the syringe support via the attachment.
A medicament delivery device comprises a housing and a syringe axially movable in the housing and the syringe having a barrel. The device further comprises a stopper axially movable in the barrel and which separates a first chamber and second chamber from one another. The stopper is axially movable in the barrel in response to a vapour pressure being received in the second chamber. The device also includes a biasing mechanism to axially move the syringe in the housing between a first syringe position and a second syringe position in response to a first reduction in the vapour pressure in the second chamber. In the first syringe position venting of the propellant from the second chamber through a first fluid pathway is permitted to enable the first reduction in the vapour pressure in the second chamber while venting of the propellant from the second chamber through a second fluid pathway is substantially prevented. In the second syringe position venting of the propellant from the second chamber through the second fluid pathway is permitted to enable a second reduction in the vapour pressure in the second chamber.
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
17 - Rubber and plastic; packing and insulating materials
40 - Treatment of materials; recycling, air and water treatment,
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Pharmaceuticals and pharmaceutical preparations; active
pharmaceutical ingredients. Medical apparatus and instruments; drug delivery devices;
inhalers; metered dose inhalers; dry powder inhalers;
inhaled drug delivery apparatus and instruments;
hydrofluoralkanes (HFA) powered devices, systems, apparatus
and instruments for use in or in relation to drug and
pharmaceutical delivery devices; hydrofluoralkanes (HFA)
powered syringes, auto-injectors and apparatus and devices
for administrating pharmaceutical and drugs;
hydrofluoralkanes (HFA) powered devices, systems, apparatus
and instruments for use in or in relation to drug and
pharmaceutical delivery devices incorporating audio, visual
and/or tactile feedback mechanisms relating to drug and
pharmaceutical delivery; hydrofluoralkanes (HFA) powered
syringes, auto-injectors and apparatus and devices for
administrating pharmaceutical and drugs incorporating audio,
visual and/or tactile feedback mechanisms relating to drug
and pharmaceutical delivery; syringes; syringe stoppers;
vials; auto-injectors; medical injectors; disposable
syringes and injectors; hypodermic syringes and injectors;
apparatus and devices for administering pharmaceuticals and
drugs; sterile apparatus for the administration of
pharmaceuticals and drugs; cartridges for syringes; nozzles
for syringes; drug delivery apparatus; oral and nasal
medication dispensers; aerosol dispensers for medical
purposes; parts and fittings for all the aforesaid; valves,
pumps and actuators for dispensing aerosols and powders;
valves, pumps and actuators for use in inhalers and/or drug
dispensing and delivery devices; parts and fittings for all
the aforesaid goods; elastomer parts for valves, pumps and
actuators, for medical apparatus and instruments and for
drug delivery devices. Goods made of rubber or imitation rubber; gaskets. Custom manufacture of medical apparatus and instruments,
inhalers and drug delivery products, pharma and medical
related products and apparatus; custom manufacture of
components, parts and fittings for all the aforesaid
products; management of product lifecycles for others, in
the nature of custom manufacturing of medical apparatus and
instruments, inhalers and drug delivery products, pharma and
medical related products and apparatus; provision of
injection moulding services; custom manufacture of active
pharmaceutical ingredients for others; custom manufacture of
pharmaceuticals for others; advisory, consultancy and
information services relating to all the aforesaid. Provision of training, teaching and educational services;
advisory, consultancy and information services relating to
all the aforesaid. Design and development of medical apparatus and instruments
for others; design and development of inhalers and drug
delivery products for others; design and development of
pharmaceuticals, pharma and medical related products and
apparatus for others; prototyping services; metrology
services; laboratory services relating to analytic testing;
quality testing services; quality control advisory services
namely regulatory quality control advisory services relating
to pharmaceuticals, active pharmaceutical ingredients,
medical apparatus and instruments, inhalers and drug
delivery products, pharma and medical related products and
apparatus; management of product lifecycles for others, in
the nature of conducting and managing clinical trials and
trials of medical apparatus and instruments, inhalers and
drug delivery products, pharma and medical related products
and apparatus; advisory, consultancy and information
services relating to all the aforesaid.
17.
A MEDICAMENT DELIVERY DEVICE WITH A REMOVABLE CAP AND LOCKING MEMBER FOR PREVENTING ACCIDENTAL ACTIVIATION
There is provided a medicament delivery device comprising a housing for receiving a syringe, the housing having first and second casing parts separably attachable to one another. The device further comprising a sleeve receivable within the housing and including a tubular wall having an inner surface delimiting a bore and an opposing outer surface. A locking member is receivable within the second casing part such that the locking member is axially movable between first and second axial positions relative to the second casing part. In the first axial position the locking member is engageable with the outer surface to inhibit an axial movement of the sleeve relative to the first casing part. In the second axial position the locking member is disengageable from the outer surface. The device may have application as an autoinjector.
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
A61M 5/315 - Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod; Appliances on the rod for facilitating dosing
A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
17 - Rubber and plastic; packing and insulating materials
40 - Treatment of materials; recycling, air and water treatment,
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Pharmaceuticals and pharmaceutical preparations for the treatment of dermatological, cardiovascular, haematological, bone, respiratory, central nervous system, endocrinological, circulatory, gastroenterological, stomach, digestive, hormonal, diabetic, muscular, rheumatic, immune system, ocular and metabolic diseases and disorders, drug addiction and opioid addiction; active pharmaceutical ingredients in the form of tablets, liquids, powders and skin patches and coatings for tablets and powders that facilitate the delivery of pharmaceuticals Medical apparatus and instruments for the delivery of drugs and medicines; drug delivery devices; inhalers for medical use; metered dose inhalers for medical use; dry powder inhalers for medical use; inhaled drug delivery apparatus and instruments in the nature of a drug delivery system; hydrofluoralkanes (HFA) powered infusion and injection devices, systems, apparatus and instruments for use in drug and pharmaceutical delivery; hydrofluoralkanes (HFA) powered syringes, auto-injectors and injection devices for administrating pharmaceuticals and drugs; hydrofluoralkanes (HFA) powered infusion and injection devices, systems, apparatus and instruments for use in drug and pharmaceutical delivery incorporating audio, visual and/or tactile feedback mechanisms relating to drug and pharmaceutical delivery; hydrofluoralkanes (HFA) powered syringes, auto-injectors and injection devices for administrating pharmaceuticals and drugs incorporating audio, visual and tactile feedback mechanisms relating to drug and pharmaceutical delivery; syringes; syringe stoppers specially adapted for medical syringes; auto-injectors for pharmaceuticals; medical injectors for pharmaceuticals; disposable medical syringes and injectors; hypodermic syringes and injectors for pharmaceuticals; infusion and injection devices for administering pharmaceuticals and drugs; sterile apparatus for the administration of pharmaceuticals and drugs; cartridges specially adapted for medical syringes; nozzles specially adapted for medical syringes; drug delivery systems; oral and nasal medication aerosol dispensers; aerosol dispensers for medical purposes; parts and fittings for all the aforesaid; valves, pumps and actuators specially adapted for medical dispensers aerosols and powders; valves, pumps and actuators specially adapted for use in medical dispensers inhalers and drug dispensing and delivery systems; parts and fittings for all the aforesaid goods; elastomer parts for valves, pumps and actuators, specially adapted for medical apparatus and instruments for the delivery of drugs and medicines and for drug delivery systems Gaskets made of rubber or imitation rubber for use in systems for the delivery of drugs and medicines; non-metal gaskets for medical use Custom manufacture of medical apparatus and instruments, inhalers and drug delivery products, pharma and medical products and apparatus; custom manufacture of components, parts and fittings for all the aforesaid products; management of product lifecycles for others, in the nature of custom manufacturing of medical apparatus and instruments, inhalers and drug delivery products, pharma and medical products and apparatus; provision of injection moulding services of plastic for others; custom manufacture of active pharmaceutical ingredients for others; custom manufacture of pharmaceuticals for others; advisory, consultancy and information services relating to all the aforesaid Provision of training, teaching and educational services in the nature of classes and tutorials all in the field of the delivery of drugs, pharmaceuticals and medicines; advisory, consultancy and information services relating to all the aforesaid Product design and development of medical apparatus and instruments for others; product design and development of inhalers and drug delivery products for others; product design and development of pharmaceuticals, pharma and medical products and apparatus for others; prototyping services namely the development and manufacture of prototype products for use in the medical industry; metrology services; scientific laboratory services in the field of analytic testing; product quality testing services; quality control advisory services namely regulatory quality control advisory services in the field of pharmaceuticals, active pharmaceutical ingredients, medical apparatus and instruments, inhalers and drug delivery products, pharma and medical products and apparatus; management of product lifecycles for others, in the nature of conducting and managing clinical trials and trials of medical apparatus and instruments, inhalers and drug delivery products, pharma and medical products and apparatus; advisory, consultancy and information services relating to all the aforesaid
A medicament delivery device comprises a housing and a syringe axially movable in the housing and the syringe having a barrel. The device further comprises a stopper axially movable in the barrel and which separates a first chamber and second chamber from one another. The stopper is axially movable in the barrel in response to a vapour pressure being received in the second chamber. The device also includes a biasing mechanism to axially move the syringe in the housing between a first syringe position and a second syringe position in response to a first reduction in the vapour pressure in the second chamber. In the first syringe position venting of the propellant from the second chamber through a first fluid pathway is permitted to enable the first reduction in the vapour pressure in the second chamber while venting of the propellant from the second chamber through a second fluid pathway is substantially prevented. In the second syringe position venting of the propellant from the second chamber through the second fluid pathway is permitted to enable a second reduction in the vapour pressure in the second chamber.
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
A61M 5/315 - Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod; Appliances on the rod for facilitating dosing
A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
A medicament delivery device comprises a housing and a syringe axially movable in the housing and the syringe having a barrel. The device further comprises a stopper axially movable in the barrel and which separates a first chamber and second chamber from one another. The stopper is axially movable in the barrel in response to a vapour pressure being received in the second chamber. The device also includes a biasing mechanism to axially move the syringe in the housing between a first syringe position and a second syringe position in response to a first reduction in the vapour pressure in the second chamber. In the first syringe position venting of the propellant from the second chamber through a first fluid pathway is permitted to enable the first reduction in the vapour pressure in the second chamber while venting of the propellant from the second chamber through a second fluid pathway is substantially prevented. In the second syringe position venting of the propellant from the second chamber through the second fluid pathway is permitted to enable a second reduction in the vapour pressure in the second chamber.
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
A61M 5/315 - Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod; Appliances on the rod for facilitating dosing
A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
A medicament delivery device (10) comprising a syringe (12) having a barrel with an open end, and an axially moveable stopper (18) received in the barrel separating a first chamber axially forwards of the stopper from a second chamber axially rearwards of the stopper. The medicament delivery device further including an expandable drive housing (24) arranged to receive a propellant from a propellant source (36) for providing a vapour pressure, the expandable drive housing having a narrow channel in fluid communication with the second chamber. The expandable drive housing is expandable upon receiving propellant from the propellant source and, upon expansion, causes forward axial movement of the syringe. Propellant introduced into the expandable housing may pass through the narrow channel into the second chamber and cause forward axial movement of the stopper in the barrel to expel medicament contained in the first chamber through the open end, where axial movement of the stopper in the barrel commences after axial movement of the syringe.
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
A valved container assembly has a container for containing a fluid, extending in an axial direction, and having an open front end and a valve disposed in the container. A plunger element is disposed axially rearward of the valve and is axially moveable in the container. The plunger element is configured to increase the pressure of a fluid in a first volume of the container upon axial movement of the plunger element relative to the valve. The valve includes a channel bypassing a seal, the channel having a first opening in fluid communication with the atmosphere outside of the valved container assembly and a second opening selectively sealed from the first volume by a resilient seal. The resilient seal is moveable from a sealing configuration to an open configuration upon the pressure of the fluid in the first volume exceeding a first pressure threshold.
B05B 7/24 - Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas with means, e.g. a container, for supplying liquid or other fluent material to a discharge device
Provided is a housing part for an auto-injector comprising a shell form body defining inner and outer shell surfaces and comprising a relatively hard or generally incompressible material; an over-coating formed of a relatively softer or more compressible material, the over-coating covering at least part of the outer shell surface of the shell form body; and at least one window defined in the shell form body, wherein the over-coating extends into the at least one window. Also provided is a housing comprising the housing part, and an auto-injector comprising the housing.
A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
A61M 5/315 - Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod; Appliances on the rod for facilitating dosing
An injection device having an outer housing configured to receive a syringe. The syringe has a barrel for containing medicament and a needle in fluid communication with the barrel. The device further has a needle shield axially moveable relative to the outer housing between a needle covering position and a needle exposing position and a biasing means to bias the needle shield axially forwardly toward the needle covering position. A locking sleeve, axially movable relative to the outer housing between a non- locking position and a locking position, selectively limits axial movement of the needle shield. In a first configuration, the needle shield is axially slideable within the locking sleeve to permit rearward axial movement of the needle shield from the needle covering position to the needle exposing position. In a subsequent configuration, the needle shield is prevented from moving axially rearwardly by interference with the locking sleeve, thereby maintaining the needle shield in the needle protecting position. The device may reduce the risk of needle stick injuries when compared to known injection devices and also may prevent unintentional reuse of the device.
A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
A61M 5/50 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
A seal for a valve for use in a pharmaceutical dispensing device, which seal comprises: (a) a first elastomer based on an ethylene-propylene-diene terpolymer, which terpolymer comprises from 45 to 55 wt.% ethylene, from 40 to 50 wt.% propylene, and ENB (ethylidenenorbornene) in an amount of 0.5 to 6 wt.%, wherein the terpolymer has a Mooney Viscosity (ML 1 + 4, 125º C) of from 10 to 30; and (b) a second elastomer based on an ethylene-propylene-diene terpolymer, which terpolymer comprises from 45 to 55 wt.% ethylene, from 40 to 50 wt.% propylene, and ENB (ethylidenenorbornene) in an amount of 0.5 to 6 wt.%, wherein the terpolymer has a Mooney Viscosity (ML 1 + 4, 125º C) of from 60 to 80.
The present invention provides dose counter for displaying a count indication of the number or quantity of doses dispensed from or remaining in a container associated, in use, with the dose counter, comprising an indicator member comprising dose indicia and a priming indicator for prompting a user to carry out one or more priming actuations of the container. The priming indicator is initially arranged to at least partially overly the indicator member to thereby at least partially obscure viewing of the dose indicia of the indicator member until the one or more priming actuations of the container have been completed. The priming indicator is movable after the one or more priming actuations have been completed into a disposition where it no longer obscures viewing of the dose indicia of the indicator member. The invention also provides a dispensing apparatus comprising the dose counter.
G06M 1/22 - Design features of general application for visual indication of the result of count on counting mechanisms, e.g. by window with magnifying lens
G06M 1/04 - Design features of general application for driving the stage of lowest order
B65D 83/14 - Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
A dispensing apparatus (1) is provided comprising a fluid reservoir (4) and a valve (2). The fluid reservoir comprising a body which defines an internal volume which contains a fluid and the body comprising an open mouth. The valve (2) is sealingly coupled to the body of the fluid reservoir (4) to close the open mouth and the valve comprises a gasket seal (18) which engages the body of the fluid reservoir. The gasket seal (18) comprises an elastomer based on an ethylene-propylene- diene terpolymer, which terpolymer comprises from 45 to 55 wt.% ethylene, from 40 to 50 wt.% propylene, and ENB (ethylidenenorbornene) in an amount of 0.5 to 6 wt.%; and wherein the fluid comprises comprises a halogenated ether.
C08F 210/18 - Copolymers of ethene with alpha-alkenes, e.g. EP rubbers with non-conjugated dienes, e.g. EPT rubbers
C09J 123/16 - Ethene-propene or ethene-propene-diene copolymers
A61M 16/18 - Vaporising devices for anaesthetic preparations
A61M 16/10 - Preparation of respiratory gases or vapours
A61M 16/01 - Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes specially adapted for anaesthetising
A medicament delivery device (10) comprising a syringe (12) having a barrel with an open end, and an axially moveable stopper (18) received in the barrel separating a first chamber axially forwards of the stopper from a second chamber axially rearwards of the stopper. The medicament delivery device further including an expandable drive housing (24) arranged to receive a propellant from a propellant source (36) for providing a vapour pressure, the expandable drive housing having a narrow channel in fluid communication with the second chamber. The expandable drive housing is expandable upon receiving propellant from the propellant source and, upon expansion, causes forward axial movement of the syringe. Propellant introduced into the expandable housing may pass through the narrow channel into the second chamber and cause forward axial movement of the stopper in the barrel to expel medicament contained in the first chamber through the open end, where axial movement of the stopper in the barrel commences after axial movement of the syringe.
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
A medicament delivery device has a syringe, a housing, a needle shield, a biasing member and one or more blocking members. The needle shield is biased axially forwardly by the biasing member so as to selectively cover a needle of the syringe. However, the biasing member is prevented from biasing the needle shield axially forwardly until a radial movement of the blocking members has occurred, which is precipitated by a forward axial movement of the syringe. Consequently, the forward movement of the syringe releases the needle shield to automatically make safe the device.
A medicament delivery device (10) comprising a syringe (12) having a barrel with an open end, and an axially moveable stopper (18) received in the barrel separating a first chamber axially forwards of the stopper from a second chamber axially rearwards of the stopper. The medicament delivery device further including an expandable drive housing (24) arranged to receive a propellant from a propellant source (36) for providing a vapour pressure, the expandable drive housing having a narrow channel in fluid communication with the second chamber. The expandable drive housing is expandable upon receiving propellant from the propellant source and, upon expansion, causes forward axial movement of the syringe. Propellant introduced into the expandable housing may pass through the narrow channel into the second chamber and cause forward axial movement of the stopper in the barrel to expel medicament contained in the first chamber through the open end, where axial movement of the stopper in the barrel commences after axial movement of the syringe.
A sub-assembly of a medicament delivery device, the sub-assembly including a housing for containing a propellant source, and a locking ring for attachment to the housing. The housing is configured to receive a flange of a syringe, the locking ring is configured to retain a syringe flange received in the housing between the locking ring and the housing when the locking ring is attached to the housing.
A sub-assembly of a medicament delivery device, the sub-assembly including a propellant source having a reservoir housing defining a reservoir and a stem having a bore therethrough, at least one inlet in fluid communication with the bore, and an open outlet end in fluid communication with the bore, the stein being moveable relative to the reservoir housing between a first position in which the at least one inlet is not in fluid communication with the reservoir and a second position in which the at least one inlet is in fluid communication with the reservoir, the propellant source further including a biasing member for biasing the stem towards the first position. The sub-assembly further including a collet member having a first plurality of radially flexible fingers and a second plurality of radially flexible fingers.
A medicament delivery device including a first container having a delivery outlet at a front end thereof and a first stopper axially moveable in the first container, the first stopper defining and separating a first chamber and a second chamber in the first container, where the first chamber is axially forwards of the first stopper and the second chamber is axially rearwards of the first stopper. The medicament delivery device further includes a second container having a second stopper axially moveable in the second container, the second stopper defining and separating a third chamber and a fourth chamber in the second container, where the third chamber is axially forwards of the second stopper and the fourth chamber is axially rearwards of the second stopper, and where the third chamber has a vent outlet in fluid communication with a venting chamber.
A syringe assembly comprising a barrel for containing one or more medicaments, the barrel having a front outlet for allowing the expulsion of said one or more medicaments from the said barrel through said outlet, and a first stopper disposed in the barrel and axially moveable therein and defining a first volume in the barrel axially forwards of the first stopper and a second volume in the barrel axially rearwards of the first stopper. The first stopper has a two way valve that is moveable between a sealing configuration and an open configuration to selectively put the first volume in fluid communication with the second volume. The two way valve is moveable from the sealing configuration to the open configuration by an increase in fluid pressure in either of the first and second volumes. The syringe assembly additionally comprises a second stopper disposed in the barrel axially rearward of the first stopper and axially moveable therein, the second stopper providing a fluid tight seal at a rear end of the second volume. The syringe assembly further comprises a first plunger rod connected to the first stopper and extending axially rearwardly through the second stopper, the second stopper sealingly engaging with the first plunger rod but permitting axial sliding of the first plunger rod therethrough. The first plunger rod is axially moveable so as to axially move the first stopper and pressurise either of the first volume and second volume causing the two way valve to move into the open configuration and fluidly connect the first volume and second volume.
A sub-assembly for a medicament delivery device including a housing, a propellant source contained in and axially moveable relative to said housing, and a button axially moveable relative to said housing. At least part of said button is disposed axially rearwardly of part of said propellant source. The button includes one or more radially flexible blocking members, and the button is moveable between a first axial position in which the one or more radially flexible blocking members are radially restrained by the housing in a radially inward position that limits rearward axial movement of the propellant source, and a second axial position in which the one or more radially flexible blocking members are able to flex to a radially outward position and permit rearward axial movement of the propellant source relative to the button and the housing.
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
A61M 5/46 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests having means for controlling depth of insertion
Fluid delivery device for discharging a fluid, having: a housing; piston pump; biasing mechanism; and trigger mechanism. The housing has a basal end and a discharge end with outlet for discharging the fluid. The piston pump has a casing defining a pump chamber for storage of fluid, a piston slidably movable relative to the pump chamber, a piston plunger, and a delivery channel. The trigger mechanism is movable from a cocked configuration wherein the trigger mechanism prevents transfer of a biasing force of the biasing mechanism to the casing to a triggered configuration with the trigger mechanism enabling transfer of the biasing force to the casing to cause movement of the casing towards the housing outlet to discharge fluid from the pump chamber, along the delivery channel and out of the outlet of the housing. The biasing mechanism has one or more flexible catch members and a manually operable trigger.
A61M 15/08 - Inhaling devices inserted into the nose
B05B 11/00 - Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
A61F 9/00 - Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
Provided is a housing part for an auto-injector comprising a shell form body defining inner and outer shell surfaces and comprising a relatively hard or generally incompressible material; an over-coating formed of a relatively softer or more compressible material, the over-coating covering at least part of the outer shell surface of the shell form body; and at least one window defined in the shell form body, wherein the over-coating extends into the at least one window. Also provided is a housing comprising the housing part, and an auto- injector comprising the housing.
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
Provided is a housing part for an auto-injector comprising a shell form body defining inner and outer shell surfaces and comprising a relatively hard or generally incompressible material; an over-coating formed of a relatively softer or more compressible material, the over-coating covering at least part of the outer shell surface of the shell form body; and at least one window defined in the shell form body, wherein the over-coating extends into the at least one window. Also provided is a housing comprising the housing part, and an auto- injector comprising the housing.
A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
the deflector configured such that, on rotation of the inner wheel, the drive arm is intermittently deflected and brought into contact with the secondary indexing teeth to rotate the outer wheel about the axis of rotation.
G06M 1/04 - Design features of general application for driving the stage of lowest order
G06M 1/16 - Design features of general application for transferring a condition from one stage to a higher stage self-operating, e.g. by Geneva mechanism
The present invention provides dose counter for displaying a count indication of the number or quantity of doses dispensed from or remaining in a container associated, in use, with the dose counter, comprising an indicator member comprising dose indicia and a priming indicator for prompting a user to carry out one or more priming actuations of the container. The priming indicator is initially arranged to at least partially overly the indicator member to thereby at least partially obscure viewing of the dose indicia of the indicator member until the one or more priming actuations of the container have been completed. The priming indicator is movable after the one or more priming actuations have been completed into a disposition where it no longer obscures viewing of the dose indicia of the indicator member. The invention also provides a dispensing apparatus comprising the dose counter.
G06M 1/04 - Design features of general application for driving the stage of lowest order
G06M 1/22 - Design features of general application for visual indication of the result of count on counting mechanisms, e.g. by window with magnifying lens
A syringe for use in an autoinjector, the syringe comprising a barrel having a front outlet, an open rear end, and a tubular body extending between the front outlet and open rear end. The tubular body has an internal diameter and defines a volume for containing medicament, and the open rear end has a diameter substantially equal to or greater than the internal diameter of the tubular body. The syringe further comprises a polymeric elongate plunger rod having a stopper at a forward end and a resilient outer layer along the length of the elongate plunger rod, where the elongate plunger rod is disposable within the barrel such that the stopper seals against the inside of the tubular body of the barrel and is slidable therein by axial translation of the plunger rod in the barrel.
wherein the valve further comprises a locking member which is configured to prevent return of the valve stem into the non-dispensing position once the valve stem slides beyond a locking position.
B65D 83/00 - Containers or packages with special means for dispensing contents
B65D 83/24 - Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant characterised by the actuating means with means to hold valve open
B65B 51/26 - Devices specially adapted for producing transverse or longitudinal seams in webs or tubes
B65B 51/30 - Devices, e.g. jaws, for applying pressure and heat successively, e.g. for subdividing filled tubes
B65B 31/04 - Evacuating, pressurising or gasifying filled containers or wrappers by means of nozzles through which air or other gas, e.g. an inert gas, is withdrawn or supplied
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
A61M 5/155 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons pressurised by gas
A61M 5/168 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters
A61M 5/44 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests having means for cooling or heating the devices or media
B65D 83/48 - Lift valves, e.g. operated by push action
A syringe propellable by a propellant that boils at a predetermined temperature, the syringe comprising a barrel having an outlet at a front end, a stopper axially moveable in the barrel, and a third chamber for containing propellant. The stopper defines and separates a first chamber and a second chamber, the first chamber being axially forwards of the stopper and being configured for containing a medicament, and the second chamber being axially rearwards of the stopper and being configured to receive propellant for acting on the stopper to move the stopper axially forwardly in the barrel to expel medicament through the outlet upon actuation of the syringe. The syringe is configured such that, in use, upon actuation of the syringe, liquid propellant is released from the third chamber and boils outside of the third chamber at or above the predetermined temperature to provide an increasing vapor pressure in the second chamber that causes the stopper to move axially forwardly and begin to expel medicament from the first chamber through the outlet. During forward axial movement of the stopper in the barrel, propellant vents away from the second chamber through a vent hole.
B65D 83/24 - Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant characterised by the actuating means with means to hold valve open
B65D 83/48 - Lift valves, e.g. operated by push action
B65B 51/26 - Devices specially adapted for producing transverse or longitudinal seams in webs or tubes
B65B 51/30 - Devices, e.g. jaws, for applying pressure and heat successively, e.g. for subdividing filled tubes
B65B 31/04 - Evacuating, pressurising or gasifying filled containers or wrappers by means of nozzles through which air or other gas, e.g. an inert gas, is withdrawn or supplied
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
A61M 5/155 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons pressurised by gas
A61M 5/168 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters
A61M 5/44 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests having means for cooling or heating the devices or media
A61M 5/145 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons
b). The resilient seal (18) is moveable from the sealing configuration to the open configuration upon fluid pressure in the first volume (22) exceeding a predetermined pressure threshold.
B05B 11/00 - Single-unit hand-held apparatus in which flow of contents is produced by the muscular force of the operator at the moment of use
B05B 11/02 - Membranes or pistons acting on the contents inside the container, e.g. follower pistons
B65D 83/00 - Containers or packages with special means for dispensing contents
A61M 15/08 - Inhaling devices inserted into the nose
A61M 11/06 - Sprayers or atomisers specially adapted for therapeutic purposes of the injector type
B05C 17/005 - Hand tools or apparatus using hand-held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material through an outlet orifice by pressure
A61M 5/24 - Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or cartridges, e.g. automatic
A sub-assembly of a medicament delivery device, the sub-assembly comprising a propellant source comprising a reservoir housing defining a reservoir and a stem having a bore therethrough, at least one inlet in fluid communication with the bore, and an open outlet end in fluid communication with the bore, the stem being moveable relative to the reservoir housing between a first position in which the at least one inlet is not in fluid communication with the reservoir and a second position in which the at least one inlet is in fluid communication with the reservoir, the propellant source further comprising a biasing member for biasing the stem towards the first position. The sub-assembly further comprising a collet member having a first plurality of radially flexible fingers and a second plurality of radially flexible fingers wherein the first plurality of radially flexible fingers extend radially inwards of the second plurality of radially flexible fingers when each of said first and second plurality of radially flexible fingers are unbiased. The first plurality of radially flexible fingers are configured to engage the stem so as to inhibit axial movement of the stem relative to the collet member when the stem is urged in an axial direction with a force less than a force threshold but permit axial movement of the stem relative to the collet member when the stem is urged in an axial direction with a force greater than or equal to the force threshold. The second plurality of radially flexible fingers do not prevent axial movement of the stem relative to the collet member when in a radially outward position but engage the stem when in a biased radially inward position so as to inhibit axial movement of the stem relative to the collet member including when the stem is urged in an axial direction with a force that is substantially equal to or greater than the force threshold and that is substantially equal to or greater than the force required to compress the biasing member and permit the stem to move to the second position relative to the reservoir housing. The force threshold is substantially equal to or less than the force required to compress the biasing member.
A sub-assembly of a medicament delivery device, the sub-assembly comprising a housing for containing a propellant source, and a locking ring for attachment to the housing. The housing is configured to receive a flange of a syringe, the locking ring is configured to retain a syringe flange received in the housing between the locking ring and the housing when the locking ring is attached to the housing.
A sub-assembly for a medicament delivery device, the sub-assembly comprising a housing, a propellant source contained in and axially moveable relative to said housing, and a button axially moveable relative to said housing. At least part of said button is disposed axially rearwardly of part of said propellant source. The button includes one or more radially flexible blocking members, and the button is moveable between a first axial position in which the one or more radially flexible blocking members are radially restrained by the housing in a radially inward position that limits rearward axial movement of the propellant source, and a second axial position in which the one or more radially flexible blocking members are able to flex to a radially outward position and permit rearward axial movement of the propellant source relative to the button and the housing.
A61M 5/315 - Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod; Appliances on the rod for facilitating dosing
A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
A61M 5/46 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests having means for controlling depth of insertion
The present application is directed to a medicament delivery device comprising a first container having a delivery outlet and a first stopper axially moveable in the first container, the first stopper defining and separating a first chamber and a second chamber in the first container; and a second container having a second stopper axially moveable in the second container, the second stopper defining and separating a third chamber and a fourth chamber in the second container, wherein the first stopper is connected to the second stopper by a tensile member such that movement of the first stopper causes the second stopper to move, venting viscous fluid to retard the axial movement of the second stopper and the first stopper.
A medicament delivery device comprising a first container having a delivery outlet at a front end thereof and a first stopper axially moveable in the first container, the first stopper defining and separating a first chamber and a second chamber in the first container, where the first chamber is axially forwards of the first stopper and the second chamber is axially rearwards of the first stopper. The medicament delivery device further comprising a second container having a second stopper axially moveable in the second container, the second stopper defining and separating a third chamber and a fourth chamber in the second container, where the third chamber is axially forwards of the second stopper and the fourth chamber is axially rearwards of the second stopper, and where the third chamber has a vent outlet in fluid communication with a venting chamber. The first stopper is connected to the second stopper by a tensile member such that axially forwardly movement of the first stopper causes axially forwardly movement of the second stopper due to tensioning of the tensile member. The first stopper is driveable in an axially forwardly direction, the first chamber is configured to contain medicament for delivery through the delivery outlet as the first stopper moves axially forwards, the third chamber contains a viscous fluid that enters the venting chamber via the vent outlet as the second stopper moves axially forwards, and the fourth chamber has a pressure that is substantially equal to or greater than the pressure of the venting chamber. As the first stopper is driven axially forwardly, the tensile member is tensioned and causes the second stopper to move axially forwardly and the venting of viscous fluid into the venting chamber via the vent outlet retards the axially forward movement of the second stopper and the first stopper.
A sub-assembly of a medicament delivery device comprising a propellant source having a reservoir for containing a propellant and a stem for dispensing propellant from the reservoir, the stem extending axially along a longitudinal axis and having an open outlet end and a bore therethrough that is in fluid communication with said open outlet end and is selectively in fluid communication with said reservoir. The sub-assembly also comprising a spray head member attachable to the stem. The spray head member is arranged to radially deflect propellant passing through the bore of the stem relative to the longitudinal axis.
A valved container assembly which has a container for containing a fluid, the container extending in an axial direction and having an open front end and a valve disposed in the container. The valved container assembly is configured so that forward axial movement of the valve relative to the container is inhibited. A plunger element is disposed axially rearward of the valve and is axially moveable in the container. The plunger element is configured to increase the pressure of a fluid in a first volume of the container upon forward axial movement relative to the valve. The valve includes a channel bypassing the permanent seal, the channel having a first opening in fluid communication with the atmosphere outside of the valved container assembly and a second opening selectively sealed from the first volume by a resilient seal.
B05B 7/24 - Spraying apparatus for discharge of liquids or other fluent materials from two or more sources, e.g. of liquid and air, of powder and gas with means, e.g. a container, for supplying liquid or other fluent material to a discharge device
An assembly for an auto injector device, the assembly including a syringe support for supporting a syringe by limiting forward axial movement of the syringe relative to the syringe support, and a guard element attachable to the syringe support by an attachment so that the guard element is axially restrained both axially forwardly and axially rearwardly relative to the syringe support by the attachment. Forwardly directed axial loads received by the guard element are transmitted to the syringe support via the attachment.
An assembly for an auto injector device, the assembly including a syringe support for supporting a syringe by limiting forward axial movement of the syringe relative to the syringe support, and a guard element attachable to the syringe support by an attachment so that the guard element is axially restrained both axially forwardly and axially rearwardly relative to the syringe support by the attachment. Forwardly directed axial loads received by the guard element are transmitted to the syringe support via the attachment.
A fluid delivery device for discharging a fluid comprising: a housing; piston pump; biasing mechanism; and trigger mechanism. The housing comprises a basal end and a discharge end having an outlet for discharging the fluid. The piston pump comprises a casing defining a pump chamber for storage of the fluid, piston slidably movable relative to the pump chamber, piston plunger, and delivery channel. The trigger mechanism movable from a cocked configuration wherein the trigger mechanism prevents transfer of a biasing force of the biasing mechanism to the casing to thereby prevent movement of the casing towards the outlet of the housing to a triggered configuration wherein the trigger mechanism enables transfer of the biasing force to the casing to thereby cause movement of the casing towards the outlet of the housing so as to discharge fluid from the pump chamber, along the delivery channel and out of the outlet.
A fluid delivery device for discharging a fluid comprising: a housing; piston pump; biasing mechanism; and trigger mechanism. The housing comprises a basal end and a discharge end having an outlet for discharging the fluid. The piston pump comprises a casing defining a pump chamber for storage of the fluid, piston slidably movable relative to the pump chamber, piston plunger, and delivery channel. The trigger mechanism movable from a cocked configuration wherein the trigger mechanism prevents transfer of a biasing force of the biasing mechanism to the casing to thereby prevent movement of the casing towards the outlet of the housing to a triggered configuration wherein the trigger mechanism enables transfer of the biasing force to the casing to thereby cause movement of the casing towards the outlet of the housing so as to discharge fluid from the pump chamber, along the delivery channel and out of the outlet of the housing. The biasing mechanism comprises one or more flexible catch members and a manually operable trigger.
A syringe assembly having a barrel for containing one or more medicaments and a stopper disposed in the barrel defining and separating a first volume and a second volume within the syringe assembly. The stopper includes a permanent seal fluidly sealing the stopper to the barrel about the entire perimeter of the stopper intermediate the first volume and second volume, and a channel bypassing the permanent seal, the channel having a first opening in fluid communication with the second volume and a second opening selectively sealed from the first volume by a resilient seal. The resilient seal is moveable between a sealing configuration and an open configuration to selectively seal the channel from the first volume and is moveable from the sealing configuration to the open configuration upon fluid pressure in the first volume or second volume exceeding a first pressure threshold.
A61M 5/28 - Syringe ampoules or cartridges, i.e. ampoules or cartridges provided with a needle
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
A61M 5/315 - Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod; Appliances on the rod for facilitating dosing
A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
A syringe assembly comprising a barrel for containing one or more medicaments, the barrel having a front outlet for allowing the expulsion of said one or more medicaments from the said barrel through said outlet, and a first stopper disposed in the barrel and axially moveable therein and defining a first volume in the barrel axially forwards of the first stopper and a second volume in the barrel axially rearwards of the first stopper. The first stopper has a two way valve that is moveable between a sealing configuration and an open configuration to selectively put the first volume in fluid communication with the second volume. The two way valve is moveable from the sealing configuration to the open configuration by an increase in fluid pressure in either of the first and second volumes. The syringe assembly additionally comprises a second stopper disposed in the barrel axially rearward of the first stopper and axially moveable therein, the second stopper providing a fluid tight seal at a rear end of the second volume. The syringe assembly further comprises a first plunger rod connected to the first stopper and extending axially rearwardly through the second stopper, the second stopper sealingly engaging with the first plunger rod but permitting axial sliding of the first plunger rod therethrough. The first plunger rod is axially moveable so as to axially move the first stopper and pressurise either of the first volume and second volume causing the two way valve to move into the open configuration and fluidly connect the first volume and second volume.
A syringe assembly comprising a barrel for containing one or more medicaments, the barrel having a front outlet for allowing the expulsion of said one or more medicaments from the said barrel through said outlet, and a first stopper disposed in the barrel and axially moveable therein and defining a first volume in the barrel axially forwards of the first stopper and a second volume in the barrel axially rearwards of the first stopper. The first stopper has a two way valve that is moveable between a sealing configuration and an open configuration to selectively put the first volume in fluid communication with the second volume. The two way valve is moveable from the sealing configuration to the open configuration by an increase in fluid pressure in either of the first and second volumes. The syringe assembly additionally comprises a second stopper disposed in the barrel axially rearward of the first stopper and axially moveable therein, the second stopper providing a fluid tight seal at a rear end of the second volume. The syringe assembly further comprises a first plunger rod connected to the first stopper and extending axially rearwardly through the second stopper, the second stopper sealingly engaging with the first plunger rod but permitting axial sliding of the first plunger rod therethrough. The first plunger rod is axially moveable so as to axially move the first stopper and pressurise either of the first volume and second volume causing the two way valve to move into the open configuration and fluidly connect the first volume and second volume.
A fluid delivery device (1) for discharging a fluid comprises a housing (2, 3), piston pump (4), biasing mechanism (5, 101), and trigger mechanism (6); the housing (2, 3) comprising a basal end (3) and discharge end (2) having an outlet (10) for discharging the fluid; the piston pump (4) comprising a casing (20) defining a pump chamber (35) for fluid storage, piston (21) slidably movable relative to the pump chamber (35), piston plunger (22), and delivery channel (59) for delivering fluid discharged from pump chamber (35) to outlet (10); the trigger mechanism (6) being movable from cocked configuration, preventing transfer of biasing mechanism (5, 101) force to the casing (20) to prevent casing (20) movement towards the outlet (10), to triggered configuration, enabling transfer of biasing mechanism (5, 101) force to the casing (20) to cause casing (20) movement towards the outlet (10) to discharge fluid from the pump chamber (35). The biasing mechanism (5, 101) comprises one or more flexible catch members (104) which in cocked configuration are catched and in triggered configuration are decoupled from the housing (2, 3). The trigger mechanism (6) comprises a manually movable button (100) at the housing basal end (3) comprising an obstructer (114) that in cocked configuration engages the catch members (104) to prevent decoupling.
A61F 9/00 - Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
A dispensing apparatus (for delivering metered doses from a pressurized dispensing container) having a housing receiving the container and a dose counter with dose indication element. The dose counter has an indexing mechanism advancing the indication element on container actuation. The dispensing apparatus has an indexing member moving within the housing in sync with the container wherein on actuation of the container in a normal mode of operation the indexing member interfaces with the indexing mechanism to apply a force to the indexing mechanism to incrementally advance the indication element. The indexing member and mechanism are configured to cooperate with one another, upon the input of a force in a second mode, such that the indexing mechanism transmits a force to the indexing member sufficient to generate a relative displacing movement between the indexing member and mechanism without incurring incremental advancement of the indication element.
A valved container assembly (10) comprising a container (12) for containing a fluid, the container (12) extending in an axial direction and having at least one venting opening (12a) at a front end and at least one dispensing opening (12b). The valved container assembly (10) further comprising a valve (14) disposed in the container (12) and a plunger element (20) disposed axially rearward of the valve (14), the plunger element (20) being axially moveable in the container (12) and defining a first volume (22) in the container (12) between the plunger element (20) and the valve (14), where the plunger element (20) is configured to increase the pressure of a fluid in the first volume (22) upon axial movement relative to the valve (14). The valve (14) comprises a permanent seal (16) forming a fluidic seal between the at least one venting opening (12a) and the first volume (22), and a resilient seal (18) that is axially rearward of said permanent seal (16) and is moveable between a sealing configuration and an open configuration. In the sealing configuration the resilient seal (18) forms a fluidic seal with the container (12) between the at least one dispensing opening (12b) and the first volume (22). In at least one axial position of the valve (14) in the container (12) when the resilient seal (18) is in the open configuration the first volume (22) is fluidly connected to the at least one dispensing opening (12b). The resilient seal (18) is moveable from the sealing configuration to the open configuration upon fluid pressure in the first volume (22) exceeding a predetermined pressure threshold.
A valved container assembly (10) comprising a container (12) for containing a fluid, the container (12) extending in an axial direction and having at least one venting opening (12a) at a front end and at least one dispensing opening (12b). The valved container assembly (10) further comprising a valve (14) disposed in the container (12) and a plunger element (20) disposed axially rearward of the valve (14), the plunger element (20) being axially moveable in the container (12) and defining a first volume (22) in the container (12) between the plunger element (20) and the valve (14), where the plunger element (20) is configured to increase the pressure of a fluid in the first volume (22) upon axial movement relative to the valve (14). The valve (14) comprises a permanent seal (16) forming a fluidic seal between the at least one venting opening (12a) and the first volume (22), and a resilient seal (18) that is axially rearward of said permanent seal (16) and is moveable between a sealing configuration and an open configuration. In the sealing configuration the resilient seal (18) forms a fluidic seal with the container (12) between the at least one dispensing opening (12b) and the first volume (22). In at least one axial position of the valve (14) in the container (12) when the resilient seal (18) is in the open configuration the first volume (22) is fluidly connected to the at least one dispensing opening (12b). The resilient seal (18) is moveable from the sealing configuration to the open configuration upon fluid pressure in the first volume (22) exceeding a predetermined pressure threshold.
B05C 17/01 - Hand tools or apparatus using hand-held tools, for applying liquids or other fluent materials to, for spreading applied liquids or other fluent materials on, or for partially removing applied liquids or other fluent materials from, surfaces for discharging material through an outlet orifice by pressure with mechanically or electrically actuated piston or the like
B65D 83/00 - Containers or packages with special means for dispensing contents
A syringe propellable by propellant that boils at a predetermined temperature, the syringe comprising a barrel having an outlet at a front end, and a stopper axially moveable in the barrel. The stopper defines and separates a first chamber and a second chamber, the first chamber being axially forwards of the stopper and being configured for containing a medicament, and the second chamber being axially rearwards of the stopper and being configured to receive propellant for acting on the stopper to move the stopper axially forwardly in the barrel to expel medicament through the outlet upon actuation of the syringe. The syringe further comprises a rupturing portion and a third chamber for containing propellant where the third chamber is rupturable. The rupturing portion is configured to rupture the third chamber upon actuation of the syringe to fluidly connect the third chamber to the second chamber and release liquid propellant from the third chamber so that the pressure in the second chamber increases at or above the predetermined temperature causing the stopper to move axially forwardly and begin to expel medicament from the first chamber through the outlet. When propellant is released into the second chamber the pressure in the second chamber increases over a first time period to a first pressure causing the stopper to move axially forwardly to begin expulsion of medicament from the first chamber through the outlet. The syringe is configured such that while the medicament is expelled from the first chamber the pressure in the second chamber changes over a second time period from the first pressure to a second pressure. When substantially all the medicament has been expelled from the first chamber the pressure in the second chamber increases over a third time period towards a third pressure. The magnitude of the second pressure and the rate of increase of the pressure in the second chamber during the third time period are controlled by the thermal conductivity of the components of the syringe defining the second chamber, the rate of delivery of propellant to the second chamber, and the phase of the propellant during delivery into the second chamber. The third pressure is substantially equal to the vapour pressure of the propellant at ambient temperature at the instantaneous volume of the vaporised propellant, and at the third pressure the syringe contains liquid propellant.
B65B 31/04 - Evacuating, pressurising or gasifying filled containers or wrappers by means of nozzles through which air or other gas, e.g. an inert gas, is withdrawn or supplied
A61M 5/155 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons pressurised by gas
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
B65B 51/26 - Devices specially adapted for producing transverse or longitudinal seams in webs or tubes
B65B 51/30 - Devices, e.g. jaws, for applying pressure and heat successively, e.g. for subdividing filled tubes
A syringe propellable by propellant that boils at a predetermined temperature, the syringe comprising a barrel having an outlet at a front end, and a stopper axially moveable in the barrel. The stopper defines and separates a first chamber and a second chamber, the first chamber being axially forwards of the stopper and being configured for containing a medicament, and the second chamber being axially rearwards of the stopper and being configured to receive propellant for acting on the stopper to move the stopper axially forwardly in the barrel to expel medicament through the outlet upon actuation of the syringe. The syringe further comprises a third chamber for containing propellant. The syringe is configured such that, in use, upon actuation of the syringe, liquid propellant is released from the third chamber and boils outside of the third chamber at or above the predetermined temperature to provide an increasing vapour pressure in the second chamber that causes the stopper to move axially forwardly and begin to expel medicament from the first chamber through the outlet. The syringe further comprises at least one trigger for triggering an action upon activation of said trigger, wherein the trigger is activated in response to the pressure in the second chamber satisfying a predetermined condition.
B65B 31/04 - Evacuating, pressurising or gasifying filled containers or wrappers by means of nozzles through which air or other gas, e.g. an inert gas, is withdrawn or supplied
A61M 5/155 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons pressurised by gas
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
B65B 51/26 - Devices specially adapted for producing transverse or longitudinal seams in webs or tubes
B65B 51/30 - Devices, e.g. jaws, for applying pressure and heat successively, e.g. for subdividing filled tubes
A dose indicator device for a pressurised metered dose inhaler comprises an inner wheel (11), annular outer wheel (12), actuator (13) and housing (70); the inner wheel comprising primary indexing teeth and a flexible drive arm; the outer wheel comprising secondary indexing teeth on an outwards face of the outer wheel; the inner wheel and outer wheel located at least partially within the housing such that the inner wheel and outer wheel are rotatable about a common longitudinal axis of rotation; the actuator movable in a plane perpendicular to the axis of rotation to engage the primary indexing teeth to rotate the inner wheel; the housing being fixed relative to the axis of rotation and comprising a deflector; the deflector configured such that, on rotation of the inner wheel, the drive arm is intermittently deflected and brought into contact with the secondary indexing teeth to rotate the outer wheel about the axis of rotation.
G06M 1/04 - Design features of general application for driving the stage of lowest order
G06M 1/16 - Design features of general application for transferring a condition from one stage to a higher stage self-operating, e.g. by Geneva mechanism
A valve for discharging a fluid, comprising: a valve body at least partially defining a fluid chamber; and a valve stem extending into the fluid chamber, the valve stem comprising an outlet port for transfer, in use, of fluid from the fluid chamber into the valve stem; the valve stem being slidably movable relative to the valve body from: i) a non-dispensing position in which the outlet port is out of communication with the fluid chamber; to ii) a dispensing position in which the outlet port is in fluid communication with the fluid chamber so as to permit transfer of the fluid from the fluid chamber into the valve stem; wherein the valve further comprises a locking member which is configured to prevent return of the valve stem into the non-dispensing position once the valve stem slides beyond a locking position.
F16K 51/00 - Other details not peculiar to particular types of valves or cut-off apparatus
B65B 31/04 - Evacuating, pressurising or gasifying filled containers or wrappers by means of nozzles through which air or other gas, e.g. an inert gas, is withdrawn or supplied
B65B 51/26 - Devices specially adapted for producing transverse or longitudinal seams in webs or tubes
B65B 51/30 - Devices, e.g. jaws, for applying pressure and heat successively, e.g. for subdividing filled tubes
F16K 1/30 - Lift valves, i.e. cut-off apparatus with closure members having at least a component of their opening and closing motion perpendicular to the closing faces specially adapted for pressure containers
F16K 3/30 - Gate valves or sliding valves, i.e. cut-off apparatus with closing members having a sliding movement along the seat for opening and closing - Details
A valve for discharging a fluid, comprising: a valve body at least partially defining a fluid chamber; and a valve stem extending into the fluid chamber, the valve stem comprising an outlet port for transfer, in use, of fluid from the fluid chamber into the valve stem; the valve stem being slidably movable relative to the valve body from: i) a non-dispensing position in which the outlet port is out of communication with the fluid chamber; to ii) a dispensing position in which the outlet port is in fluid communication with the fluid chamber so as to permit transfer of the fluid from the fluid chamber into the valve stem; wherein the valve further comprises a locking member which is configured to prevent return of the valve stem into the non-dispensing position once the valve stem slides beyond a locking position.
B65B 31/04 - Evacuating, pressurising or gasifying filled containers or wrappers by means of nozzles through which air or other gas, e.g. an inert gas, is withdrawn or supplied
B65B 51/26 - Devices specially adapted for producing transverse or longitudinal seams in webs or tubes
B65B 51/30 - Devices, e.g. jaws, for applying pressure and heat successively, e.g. for subdividing filled tubes
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
A61M 5/155 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons pressurised by gas
A syringe propellable by propellant that boils at a predetermined temperature, the syringe comprising a barrel having an outlet at a front end, and a stopper axially moveable in the barrel. The stopper defines and separates a first chamber and a second chamber, the first chamber being axially forwards of the stopper and being configured for containing a medicament, and the second chamber being axially rearwards of the stopper and being configured to receive propellant for acting on the stopper to move the stopper axially forwardly in the barrel to expel medicament through the outlet upon actuation of the syringe. The syringe further comprises a rupturing portion and a third chamber for containing propellant where the third chamber is rupturable. The rupturing portion is configured to rupture the third chamber upon actuation of the syringe to fluidly connect the third chamber to the second chamber and release liquid propellant from the third chamber so that the pressure in the second chamber increases at or above the predetermined temperature causing the stopper to move axially forwardly and begin to expel medicament from the first chamber through the outlet. When propellant is released into the second chamber the pressure in the second chamber increases over a first time period to a first pressure causing the stopper to move axially forwardly to begin expulsion of medicament from the first chamber through the outlet. The syringe is configured such that while the medicament is expelled from the first chamber the pressure in the second chamber changes over a second time period from the first pressure to a second pressure. When substantially all the medicament has been expelled from the first chamber the pressure in the second chamber increases over a third time period towards a third pressure. The magnitude of the second pressure and the rate of increase of the pressure in the second chamber during the third time period are controlled by the thermal conductivity of the components of the syringe defining the second chamber, the rate of delivery of propellant to the second chamber, and the phase of the propellant during delivery into the second chamber. The third pressure is substantially equal to the vapour pressure of the propellant at ambient temperature at the instantaneous volume of the vaporised propellant, and at the third pressure the syringe contains liquid propellant.
B65B 31/04 - Evacuating, pressurising or gasifying filled containers or wrappers by means of nozzles through which air or other gas, e.g. an inert gas, is withdrawn or supplied
B65B 51/26 - Devices specially adapted for producing transverse or longitudinal seams in webs or tubes
B65B 51/30 - Devices, e.g. jaws, for applying pressure and heat successively, e.g. for subdividing filled tubes
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
A61M 5/155 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons pressurised by gas
A syringe propellable by propellant that boils at a predetermined temperature, the syringe comprising a barrel having an outlet at a front end, and a stopper axially moveable in the barrel. The stopper defines and separates a first chamber and a second chamber, the first chamber being axially forwards of the stopper and being configured for containing a medicament, and the second chamber being axially rearwards of the stopper and being configured to receive propellant for acting on the stopper to move the stopper axially forwardly in the barrel to expel medicament through the outlet upon actuation of the syringe. The syringe further comprises a third chamber for containing propellant. The syringe is configured such that, in use, upon actuation of the syringe, liquid propellant is released from the third chamber and boils outside of the third chamber at or above the predetermined temperature to provide an increasing vapour pressure in the second chamber that causes the stopper to move axially forwardly and begin to expel medicament from the first chamber through the outlet. The syringe further comprises at least one trigger for triggering an action upon activation of said trigger, wherein the trigger is activated in response to the pressure in the second chamber satisfying a predetermined condition.
B65B 31/04 - Evacuating, pressurising or gasifying filled containers or wrappers by means of nozzles through which air or other gas, e.g. an inert gas, is withdrawn or supplied
B65B 51/26 - Devices specially adapted for producing transverse or longitudinal seams in webs or tubes
B65B 51/30 - Devices, e.g. jaws, for applying pressure and heat successively, e.g. for subdividing filled tubes
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
A61M 5/155 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons pressurised by gas
A syringe propellable by a propellant that boils at a predetermined temperature, the syringe comprising a barrel having an outlet at a front end, a stopper axially moveable in the barrel, and a third chamber for containing propellant. The stopper defines and separates a first chamber and a second chamber, the first chamber being axially forwards of the stopper and being configured for containing a medicament, and the second chamber being axially rearwards of the stopper and being configured to receive propellant for acting on the stopper to move the stopper axially forwardly in the barrel to expel medicament through the outlet upon actuation of the syringe. The syringe is configured such that, in use, upon actuation of the syringe, liquid propellant is released from the third chamber and boils outside of the third chamber at or above the predetermined temperature to provide an increasing vapour pressure in the second chamber that causes the stopper to move axially forwardly and begin to expel medicament from the first chamber through the outlet. During forward axial movement of the stopper in the barrel, propellant vents away from the second chamber through a vent hole.
B65B 51/26 - Devices specially adapted for producing transverse or longitudinal seams in webs or tubes
B65B 51/30 - Devices, e.g. jaws, for applying pressure and heat successively, e.g. for subdividing filled tubes
A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
A61M 5/155 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons pressurised by gas
B65B 31/04 - Evacuating, pressurising or gasifying filled containers or wrappers by means of nozzles through which air or other gas, e.g. an inert gas, is withdrawn or supplied
A syringe propellable by a propellant that boils at a predetermined temperature, the syringe comprising a barrel having an outlet at a front end, a stopper axially moveable in the barrel, and a third chamber for containing propellant. The stopper defines and separates a first chamber and a second chamber, the first chamber being axially forwards of the stopper and being configured for containing a medicament, and the second chamber being axially rearwards of the stopper and being configured to receive propellant for acting on the stopper to move the stopper axially forwardly in the barrel to expel medicament through the outlet upon actuation of the syringe. The syringe is configured such that, in use, upon actuation of the syringe, liquid propellant is released from the third chamber and boils outside of the third chamber at or above the predetermined temperature to provide an increasing vapour pressure in the second chamber that causes the stopper to move axially forwardly and begin to expel medicament from the first chamber through the outlet. During forward axial movement of the stopper in the barrel, propellant vents away from the second chamber through a vent hole.
A dose indicator device for a pressurised metered dose inhaler comprises an inner wheel (11), annular outer wheel (12), actuator (13) and housing (70); • the inner wheel comprising primary indexing teeth and a flexible drive arm; • the outer wheel comprising secondary indexing teeth on an outwards face of the outer wheel; • the inner wheel and outer wheel located at least partially within the housing such that the inner wheel and outer wheel are rotatable about a common longitudinal axis of rotation; • the actuator movable in a plane perpendicular to the axis of rotation to engage the primary indexing teeth to rotate the inner wheel; • the housing being fixed relative to the axis of rotation and comprising a deflector; • the deflector configured such that, on rotation of the inner wheel, the drive arm is intermittently deflected and brought into contact with the secondary indexing teeth to rotate the outer wheel about the axis of rotation.
G06M 1/04 - Design features of general application for driving the stage of lowest order
G06M 1/16 - Design features of general application for transferring a condition from one stage to a higher stage self-operating, e.g. by Geneva mechanism
A method of manufacturing a container containing propellant comprising the steps of: i) sealing a first sheet of rupturable material to a second sheet of rupturable material to form a lower seal and two side seals; ii) placing a propellant dispensing apparatus in fluid communication with a central volume defined by said lower seal, said two side seals and a seal between the propellant dispensing apparatus and the first and second sheets; iii) depositing propellant in the central volume using said propellant dispensing apparatus; and iv) sealing the first sheet to the second sheet to form an upper seal to form a container where the propellant is contained between said upper seal, said lower seal, and said two side seals.
B65B 31/04 - Evacuating, pressurising or gasifying filled containers or wrappers by means of nozzles through which air or other gas, e.g. an inert gas, is withdrawn or supplied
B65B 51/26 - Devices specially adapted for producing transverse or longitudinal seams in webs or tubes
B65B 51/30 - Devices, e.g. jaws, for applying pressure and heat successively, e.g. for subdividing filled tubes
A syringe assembly comprising a barrel for containing one or more medicaments, a narrowed outlet for allowing the expulsion of said one or more medicaments from said barrel through said outlet; and a stopper disposed in the barrel defining and separating a first volume and a second volume within the syringe assembly. The stopper comprises a permanent seal fluidly sealing the stopper to the barrel about the entire perimeter of the stopper intermediate the first volume and second volume, and a channel bypassing the permanent seal, the channel having a first opening in fluid communication with the second volume and a second opening selectively sealed from the first volume by a resilient seal. The resilient seal is moveable between a sealing configuration and an open configuration to selectively seal the channel from the first volume, where in the sealing configuration the resilient seal fluidly seals the stopper to the barrel so as to fluidly isolate said second opening of the channel from the first volume, and in the open configuration the second opening of the channel is in fluid communication with the first volume. The resilient seal is moveable from the sealing configuration to the open configuration upon fluid pressure in the first volume or second volume exceeding a first pressure threshold.
A container assembly comprising a container, a valve disposed in the container and an axially movable plunger element disposed axially rearward of the valve. The plunger element defines a first volume in the container between the plunger element and the valve. The valve comprises a permanent seal sealing the valve to the container about the entire perimeter of the valve, and a channel bypassing the permanent seal and being in fluid communication with the atmosphere outside of the container assembly and being selectively sealed from the first volume by a resilient seal. The resilient seal is moveable from a sealing configuration to an open configuration upon fluid pressure in the first volume exceeding a first pressure threshold.
A syringe assembly comprising a barrel for containing one or more medicaments, a narrowed outlet for allowing the expulsion of said one or more medicaments from said barrel through said outlet; and a stopper disposed in the barrel defining and separating a first volume and a second volume within the syringe assembly. The stopper comprises a permanent seal fluidly sealing the stopper to the barrel about the entire perimeter of the stopper intermediate the first volume and second volume, and a channel bypassing the permanent seal, the channel having a first opening in fluid communication with the second volume and a second opening selectively sealed from the first volume by a resilient seal. The resilient seal is moveable between a sealing configuration and an open configuration to selectively seal the channel from the first volume, where in the sealing configuration the resilient seal fluidly seals the stopper to the barrel so as to fluidly isolate said second opening of the channel from the first volume, and in the open configuration the second opening of the channel is in fluid communication with the first volume. The resilient seal is moveable from the sealing configuration to the open configuration upon fluid pressure in the first volume or second volume exceeding a first pressure threshold.
A container assembly comprising a container, a valve disposed in the container and an axially movable plunger element disposed axially rearward of the valve. The plunger element defines a first volume in the container between the plunger element and the valve. The valve comprises a permanent seal sealing the valve to the container about the entire perimeter of the valve, and a channel bypassing the permanent seal and being in fluid communication with the atmosphere outside of the container assembly and being selectively sealed from the first volume by a resilient seal. The resilient seal is moveable from a sealing configuration to an open configuration upon fluid pressure in the first volume exceeding a first pressure threshold.
A fluid delivery device (1) for discharging a fluid comprises a housing (2, 3), piston pump (4), biasing mechanism (5, 101), and trigger mechanism (6); the housing (2, 3) comprising a basal end (3) and discharge end (2) having an outlet (10) for discharging the fluid; the piston pump (4) comprising a casing (20) defining a pump chamber (35) for fluid storage, piston (21) slidably movable relative to the pump chamber (35), piston plunger (22), and delivery channel (59) for delivering fluid discharged from pump chamber (35) to outlet (10); the trigger mechanism (6) being movable from cocked configuration, preventing transfer of biasing mechanism (5, 101) force to the casing (20) to prevent casing (20) movement towards the outlet (10), to triggered configuration, enabling transfer of biasing mechanism (5, 101) force to the casing (20) to cause casing (20) movement towards the outlet (10) to discharge fluid from the pump chamber (35). The biasing mechanism (5, 101) comprises one or more flexible catch members (104) which in cocked configuration are catched and in triggered configuration are decoupled from the housing (2, 3). The trigger mechanism (6) comprises a manually movable button (100) at the housing basal end (3)comprising an obstructer (114) that in cocked configuration engages the catch members (104) to prevent decoupling.
A fluid delivery device (1) for discharging a fluid comprises a housing (2, 3), piston pump (4), biasing mechanism (5, 101), and trigger mechanism (6); the housing (2, 3) comprising a basal end (3) and discharge end (2) having an outlet (10) for discharging the fluid; the piston pump (4) comprising a casing (20) defining a pump chamber (35) for fluid storage, piston (21) slidably movable relative to the pump chamber (35), piston plunger (22), and delivery channel (59) for delivering fluid discharged from pump chamber (35) to outlet (10); the trigger mechanism (6) being movable from cocked configuration, preventing transfer of biasing mechanism (5, 101) force to the casing (20) to prevent casing (20) movement towards the outlet (10), to triggered configuration, enabling transfer of biasing mechanism (5, 101) force to the casing (20) to cause casing (20) movement towards the outlet (10) to discharge fluid from the pump chamber (35). The biasing mechanism (5, 101) comprises one or more flexible catch members (104) which in cocked configuration are catched and in triggered configuration are decoupled from the housing (2, 3). The trigger mechanism (6) comprises a manually movable button (100) at the housing basal end (3)comprising an obstructer (114) that in cocked configuration engages the catch members (104) to prevent decoupling.
A fluid delivery device for discharging a fluid having a housing, a piston pump, a biasing mechanism, and a trigger mechanism. The housing has a fluid discharge outlet. The pump has a pump chamber casing for fluid storage, a piston sliding in the pump chamber, a piston plunger, and a delivery channel leading to the housing outlet. The biasing mechanism biases the piston pump casing towards the housing outlet. The trigger mechanism has a catch member and a restraining member movable by a manually actuatable trigger from a cocked to a triggered configuration. The cocked restraining member engages the catch member to prevent movement and fluid discharge. A triggered restraining member disengages from the catch member for movement of the casing towards the housing outlet to discharge fluid from housing outlet.
The present invention relates to a seal for a valve for use in a pharmaceutical dispensing device, which seal is formed from an elastomeric composition comprising: (a) one or more elastomers; and (b) a cross-linking agent comprising an aliphatic dialkyl peroxide and / or an aliphatic perketal peroxide.
B65D 83/14 - Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
C09K 3/10 - Materials not provided for elsewhere for sealing or packing joints or covers
A dispensing container (1000) comprising a canister (100) and a valve assembly (10); the canister (100) comprising: a body; a neck (102); and an open mouth for receiving the valve assembly (10); the valve assembly (10) comprising: a valve body (14); a valve stem (11); one or more dynamic seals (17,18) extending between the valve body (14) and the valve stem (11); a static gasket (16) seal for sealing between the valve body (14) and the canister (100); a spring (15) extending between the valve stem (11) and the valve body (14); and a ferrule (15); wherein the valve body (14) comprises: an outer part (14a); and an inner part; the outer part (14a) defining a seat for the static gasket seal (16); the inner part defining a seat for an inner end of the spring (25) and wherein the inner part extends through the neck (102) of the canister (100) into the body (101) of the canister (100); wherein, on assembly, the ferrule (15) holds the valve assembly (10) in place to seal the open mouth of the canister (100); characterised in that: the outer part (14a) has an outer diameter at its widest point of from 13.00 mm to 16.30 mm.
B65D 83/14 - Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
A seal for a valve for use in a pharmaceutical dispensing device, which seal is formed from a blend comprising: a thermoplastic elastomer including a propylene component with isotactic crystallinity; and a polymer selected from one or more of polypropylene, polyethylene and copolymers thereof.
C08L 9/00 - Compositions of homopolymers or copolymers of conjugated diene hydrocarbons
C08L 23/00 - Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
C08L 25/02 - Homopolymers or copolymers of hydrocarbons
C08L 27/10 - Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogen; Compositions of derivatives of such polymers not modified by chemical after-treatment containing bromine or iodine atoms
C08L 33/00 - Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical, or of salts, anhydrides, esters,; Compositions of derivatives of such polymers
C08L 35/00 - Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical, and containing at least one other c; Compositions of derivatives of such polymers
C08L 45/00 - Compositions of homopolymers or copolymers of compounds having no unsaturated aliphatic radicals in a side chain, and having one or more carbon-to-carbon double bonds in a carbocyclic or in a heterocyclic ring system; Compositions of derivatives of such polymers
A hand-held dispenser for dispensing a pharmaceutical product is disclosed. The dispenser has a housing providing a duct. A frangible membrane is provided in the duct. A probe with a piercing tip is mounted in the duct and arranged such that, in use the piercing tip pierces the frangible membrane. An air compression device is provided to compress air for expelling a pharmaceutical product through the probe and a channel is provided to substantially equalise the pressure in the air compression device and the pressure above the frangible membrane. The ability to substantially equalise the pressure in the bellows and the pressure above the frangible membrane on the sheath provides for a mote consistent release of pharmaceutical product when the frangible membrane is pierced. This is because the compressed air from the bellows which expels the pharmaceutical product through the probe does not encounter a sudden change in pressure as it passes the pierced frangible membrane with the entrained pharmaceutical product. In use, when compressed air is used to expel a pharmaceutical product through the probe, the air path through the probe has a lower resistance than the channel to substantially equalise the pressure in the air compression device and the pressure above the frangible membrane. This ensures that the majority of the compressed air is used to expel the pharmaceutical product. The piercing tip preferably comprises a generally annular cutting edge on an end portion of the probe with an interruption in the generally annular cutting edge.
A metered dose inhaler apparatus, for dispensing a metered dose of a medicinal formulation. The apparatus (200) comprises a housing (201, 202), for receiving a dispensing container (2') of medicinal formulation; a valve actuation means (206), for supplying an electrical actuation signal; and a valve actuator (204), operably-connectable to said dispensing container, for receiving the electrical actuation signal and providing actuation of said dispensing container. Wherein, the metered dose inhaler apparatus comprises dose counter means (207) operable in response to the electrical actuation signal to index the dose counter.
B65D 83/14 - Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
G01F 11/00 - Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it
An inhalation apparatus for dispensing substances for inhalation. The inhalation apparatus comprises a housing, the housing comprising an air inlet and an outlet, the housing defining a socket for receiving therein a dispensing container, the dispensing container having a portion of reduced cross sectional area. The inhalation apparatus further comprises a section of reduced diameter intermediate the air inlet and the outlet. In use, the dispensing container is movable within the socket between positions one, two and three. In the first position (the rest position) the section of reduced diameter interfaces with the dispensing container to prevent or substantially prevent flow of air between the air inlet and the outlet. In the second position (the flow position) the section of reduced diameter is at least partially aligned with the portion of reduced cross sectional area of the dispensing container to thereby form a gap sufficient to enable a flow of air between the air inlet and the outlet. The third position is associated with dispensation of a product from the dispensing container into the flow of air.
A seal for a valve for use in a pharmaceutical dispensing device, which seal is formed from a thermoplastic elastomer including a propylene component with isotactic crystallinity.
A metering valve (1) for a pressurised dispensing container comprising a metering chamber (5); an inlet (9) to the metering chamber and a separate outlet (10) to the metering chamber; one or more sealing members (7, 8) for sealing the inlet (9) to the metering chamber (5) and the outlet (10) to the metering chamber (5). The one or more sealing members (7, 8) are static and the metering chamber (5) is rotatable between a first position, in which the inlet (9) to the metering chamber is open and the outlet (10) to the metering chamber is closed, and a second position, in which the inlet (9) to the metering chamber is closed and the outlet (10) to the metering chamber is open.
F16K 11/074 - Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves; Arrangement of valves and flow lines specially adapted for mixing fluid with all movable sealing faces moving as one unit comprising only sliding valves with pivoted closure members with flat sealing faces
A metering valve for a pressurised dispensing container comprising a metering chamber (5); an inlet (9) to the metering chamber; an outlet (10) to the metering chamber; one or more inlet sealing members (7) for sealing the inlet (9) to the metering chamber (5), and one or more outlet sealing members (8) for sealing the outlet (10) to themetering chamber (5). The metering chamber (5) is static and the one or more inlet sealing members (7) are rotatable between a first position, in which the inlet (9) to the metering chamber is open, and a second position, in which the inlet (9) to the metering chamber is closed, and the one or more outlet sealing members (8) are rotatable between a first position, in which the outlet (10) to the metering chamber is closed, and a second position, in which the outlet (10) to the metering chamber is open.
F16K 11/074 - Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves; Arrangement of valves and flow lines specially adapted for mixing fluid with all movable sealing faces moving as one unit comprising only sliding valves with pivoted closure members with flat sealing faces
96.
IMPROVEMENTS IN OR RELATING TO DISPENSING APPARATUS
Dispensing apparatus comprising: a casing for housing a metering container; a counter member comprising a series of teeth and a series of indicator markings; an actuator member reciprocally moveable relative to the counter member for actuating said metering container; the actuator member comprising a driver for engaging on each reciprocal movement of the actuator member a driven tooth of the series of teeth of the counter member so as to advance the counter member in a first sense; wherein the dispensing apparatus further comprises a ramp for deflecting the driver during the reciprocal movement of the actuator member to selectively engage the driver with the series of teeth of the counter member for only a portion of the reciprocal movement.
A metering valve (10) for dispensing metered doses of a pressurised product derived from a bulk supply of a pressurised product, the metering valve comprising a valve body (14), a valve stem (11), and sealing means (17,18), the valve stem (11) comprising an outlet for the pressurised product, the valve body (14) defining an internal volume (33), the metering valve further comprising a metering chamber (12), the valve stem being movable between a non-dispensing position in which the metering chamber is, in use, in fluid communication with the bulk supply of pressurised product and a dispensing position in which the metering chamber is in fluid communication with the outlet, characterised in that, in use, the bulk supply of pressurised product is wholly contained within the internal volume (33) of the valve body (14).
B65D 83/14 - Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
A dispensing apparatus (1) comprising a housing containing a dosage counter comprising at least two annular members (11, 13) and a cog (12), each being mounted rotationally. The housing is suitable for receiving, in use, a container (1) containing a product for dispensation. Each actuation of the apparatus causes the first annular member to incrementally rotate which, after a predetermined number of actuations of the apparatus, causes the cog to rotate, the rotation of the cog causing the second annular member to incrementally rotate.
A metering valve used with a pressurized dispensing container, the metering valve has a valve stem assembly that slides co-axially within an annular metering chamber that surrounds the valve stem assembly and forms a substantially cylindrical chamber body. The metering valve also has an outer seal at the top of the cylindrical chamber body and an inner seal at the bottom of the cylindrical chamber body. The valve stem assembly has an outlet and an associated passage that is above the line of the outer seal when the metering valve is at rest, and is below the line of the outer seal when the metering valve is actuated, thereby creating a dispensing passage for the metering chamber's contents. The valve stem assembly has an inlet and an associated passage that is above the line of the inner seal when the metering valve is at rest, and is below the line of the inner seal when the metering valve is actuated. This arrangement controls the amount of material and fluid dispensed in each metered dose, as both passages are never open to the metering chamber at the same time. The valve stem assembly forms a straight, central passage extending from an open inner end of the valve stem assembly to a mid-point of the valve stem assembly located longitudinally within the metering chamber. The valve stem assembly has at least two elongated openings in a wall of the valve stem assembly to allow radially-directed flow between an exterior of the valve stem assembly and the central passage, the elongated openings being located to extend either side of the inner seal when the valve stem assembly is in the non-dispensing position. These elongated inlet passages serve to assure that the device is more reliable during use.
A seal for a valve for use in a pharmaceutical dispensing device, which seal is formed from a blend comprising: a thermoplastic elastomer including a propylene component with isotactic crystallinity; and a polymer selected from one or more of polypropylene, polyethylene and copolymers thereof.
C09K 3/10 - Materials not provided for elsewhere for sealing or packing joints or covers
B65D 83/14 - Containers or packages with special means for dispensing contents for delivery of liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
