Abstract

1222in-situ222 22 gases.

IPC Classes  ?

• B01J 37/02 - Impregnation, coating or precipitation
• B01J 35/00 - Catalysts, in general, characterised by their form or physical properties
• B01J 23/38 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of noble metals
• B01J 23/70 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper
• B01J 29/04 - Catalysts comprising molecular sieves having base-exchange properties, e.g. crystalline zeolites, pillared clays

Abstract

The present invention relates to a continuous process for the synthesis of Low Silica X (LSX) zeolite using cation exchange method. Further, the present invention relates to an apparatus (100) for production of LSX zeolites by cation exchange method. Specifically, the present invention relates to an improved continuous process for production of Li- LSX zeolites based on cation exchange method by using a continuous process reactor system. Further, the present invention provides a process with shorter time period, easily recoverable and reusable salt-solution and good adsorption capacity of the synthesized Li- LSX zeolites.

IPC Classes  ?

• C01B 39/02 - Crystalline aluminosilicate zeolitesIsomorphous compounds thereofDirect preparation thereofPreparation thereof starting from a reaction mixture containing a crystalline zeolite of another type, or from preformed reactantsAfter-treatment thereof
• C01B 39/06 - Preparation of isomorphous zeolites characterised by measures to replace the aluminium or silicon atoms in the lattice framework by atoms of other elements
• C01B 39/46 - Other types characterised by their X-ray diffraction pattern and their defined composition
• B01J 20/18 - Synthetic zeolitic molecular sieves

Abstract

The present invention provides a non-hazardous, improved continuous oxidation process for the preparation of substituted benzoic acid of formula (I) by using continuous process reactor system with improved process controls. (I) wherein: R1 is H, F, Cl, Br, I, NO2, amine, or C1-C5 alkyl; R2 is H, F, Cl, Br, I, NO2, amine, or C1-C5 alkyl; and R3 is H, F, Cl, Br, I, NO2, amine, C1-C5 alkyl; The present invention provides a non-hazardous, improved continuous oxidation process for the preparation of substituted benzoic acid of formula (I) by using continuous process reactor system with improved process controls. (I) wherein: R1 is H, F, Cl, Br, I, NO2, amine, or C1-C5 alkyl; R2 is H, F, Cl, Br, I, NO2, amine, or C1-C5 alkyl; and R3 is H, F, Cl, Br, I, NO2, amine, C1-C5 alkyl;

IPC Classes  ?

• C07C 51/275 - Preparation of carboxylic acids or their salts, halides, or anhydrides by oxidation with oxides of nitrogen or nitrogen-containing mineral acids of hydrocarbyl groups
• B01J 19/18 - Stationary reactors having moving elements inside

Abstract

The present invention discloses the design Solid State Luminogens based on pyridinum scaffolds. Particularly, the present invention discloses the design and development of novel N-doped ionic solid state emitters of general Formula (I) and to the process for preparation thereof. Variation in substituents as well counter ions of pyridinium scaffolds modulates physical properties of general Formula (I). The present invention discloses the design Solid State Luminogens based on pyridinum scaffolds. Particularly, the present invention discloses the design and development of novel N-doped ionic solid state emitters of general Formula (I) and to the process for preparation thereof. Variation in substituents as well counter ions of pyridinium scaffolds modulates physical properties of general Formula (I).

IPC Classes  ?

• C07D 471/04 - Ortho-condensed systems
• C07D 213/16 - Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
• C09K 11/06 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials

Abstract

The present invention relates to an assembly with a negatively charged dendrite inhibiting ionomer membrane made by cross-linking of sulfonated polyvinyl alcohol (PVS) and polyvinyl alcohol (PVA) for aqueous rechargeable zinc metal batteries (AZMBs).

IPC Classes  ?

• H01M 50/414 - Synthetic resins, e.g. .thermoplastics or thermosetting resins
• H01M 4/50 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese
• H01M 10/26 - Selection of materials as electrolytes
• H01M 10/42 - Methods or arrangements for servicing or maintenance of secondary cells or secondary half-cells

Abstract

Design and applications of a class of water-soluble small molecules represented by formula 1. The molecules, in their dilute aqueous solutions, exhibit lower critical solution temperature (LCST) phase transitions near room temperature, inducing a temperature triggered switching of opacity. Further, disclosed is a scalable smart window, akin to a radiative energy management system, that can be incorporated into the built environment for imparting energy efficiency. The window fabrication is facile wherein the aqueous solution is sandwiched between two transparent glass panes to enable modulation of light and heat transmission. The dynamic window of present invention represents with multifarious applications in developing scalable, smart energy management systems for indoor building environments is envisioned to be a major contribution towards cost effective smart glass technologies. Design and applications of a class of water-soluble small molecules represented by formula 1. The molecules, in their dilute aqueous solutions, exhibit lower critical solution temperature (LCST) phase transitions near room temperature, inducing a temperature triggered switching of opacity. Further, disclosed is a scalable smart window, akin to a radiative energy management system, that can be incorporated into the built environment for imparting energy efficiency. The window fabrication is facile wherein the aqueous solution is sandwiched between two transparent glass panes to enable modulation of light and heat transmission. The dynamic window of present invention represents with multifarious applications in developing scalable, smart energy management systems for indoor building environments is envisioned to be a major contribution towards cost effective smart glass technologies.

IPC Classes  ?

• C09K 19/06 - Non-steroidal liquid crystal compounds
• C09K 11/06 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials

Abstract

The specification discloses a fluorescent material having a europium precursor and a structure directing ligand comprising functionalized graphitic carbon nitride (g-C3N4). The specification also discloses a process for making the fluorescent material. Further, the specification discloses a process for using the fluorescent material to sense volatile organic compounds (VOC) in a sample. The process includes preparing the fluorescent material and sensing the VOC in the sample using the fluorescent material. The VOC is 1,4-dioxane.

IPC Classes  ?

• C09K 11/06 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials
• G01N 21/33 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using ultraviolet light
• G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups

Abstract

The present invention conveys a fractionation method to isolate different bioactive Phytocannabinoids by solid phase extraction using HP-20 resins and one step method to synthesize C— and O-β-D-glycoside derivatives of Cannabinoid by using a β-D-glucose donor (O-Glycosyl trichloroacetimidate donor) to obtain glycosidic derivatives. The novel C-glycosides of Cannabinoids displayed significant anti-proliferative properties against wide range of human cancer cell lines as compared to their respective parent molecules. Furthermore, the C— and O glycosides of Cannabinoids also showed anti-invasive and anti-migratory activities against metastatic cancer cells of breast and pancreatic origin. When applied in combination with DNA damaging agent (5-Fluorouracil) to colorectal cancer cells, the C— and O-glycosides of Cannabinoids potentiate DNA damaging property and thus augment apoptosis resulting in an increment in the efficacy of DNA damaging drugs.

IPC Classes  ?

• A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
• A61K 31/513 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
• C07H 1/08 - SeparationPurification from natural products
• C07H 7/06 - Heterocyclic radicals
• C07H 15/26 - Acyclic or carbocyclic radicals, substituted by hetero rings

Abstract

The present invention relates to the preparation of substituted triazole-5-yl(pyridine-2-yl)benzamides compounds, having structure I, in free form or an acceptable salt form for the targeted degradation of Apoptosis Signal-regulating Kinase 1 (ASK 1) as a potential therapeutic target for improves Nonalcoholic Fatty Liver Disease (NAFLD)/ Nonalcoholic Steatohepatitis (NASH). More particularly, the invention relates to small molecules where R1, R2, and R3 are as defined in the description, capable of targeted degradation of ASK1, which may ultimately be used to achieve improved human health in patients with hepatic fibrosis. The present disclosure represents the benchmark of this PROTAC technology for a potential therapeutic target protein ASK1 and will bring a breakthrough in NAFLD/NASH research.

IPC Classes  ?

• C07D 401/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
• C07D 487/02 - Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups in which the condensed system contains two hetero rings
• C07D 487/04 - Ortho-condensed systems

Abstract

The present disclosure relates to a perovskite-based mixed metal oxides represented by the formula ABX3 and a method of preparation thereof. The perovskite-based mixed metal oxide is represented by formula ABX3 wherein A is rare-earth metal(s), alkaline metal(s), ions with a large radius or mixture thereof, B represents transition metal(s), and X is oxygen and the metal oxides have a shape selected from cube, oval, rod or mixture thereof. The invention also relates to obtaining multiple shapes of a single perovskite-based mixed metal oxide with varying exposed facets affording broad tunability of the oxides.

IPC Classes  ?

• B01J 35/61 - Surface area
• B01J 23/83 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups with rare earths or actinides
• B01J 23/76 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups
• B01J 23/74 - Iron group metals

Abstract

Microfluidic impedance based lab on chip is a sensor module to measure the impedance of a single biological cell flowing in channel of micrometer size. In the present invention, the enhancement in the channel cross-section 30 micron [h]×45 micron [w] leads to reduce the pressure drop significantly i.e., around 40 kPa at 100 microliter/min, which demands by cartridge based micro-pump for portable devices at Point of Care (PoC) location. Lab on chip of present invention is capable of withstanding 20 Vpp for several hours without degradation of electrodes and also capable to measure the particle with dimension down to 2 microns. Lab on chip of present invention was also used to count the platelet of the diluted blood samples without any pretreatment and comparable to the clinical lab report.

IPC Classes  ?

• G01N 15/12 - Investigating individual particles by measuring electrical or magnetic effects by observing changes in resistance or impedance across apertures when traversed by individual particles, e.g. by using the Coulter principle
• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• G01N 15/10 - Investigating individual particles

Abstract

The present invention relates to the design of a face mask that incorporates a waste derived warp knit polyethylene terephthalate (PET) permeate spacer layer for daily usage in current pandemic conditions. The central layer in the face masks is a selective hydrophobic layer that is recycled from waste RO membrane modules and is intended for usage as a non-medicated multi-layered face mask for common man. The mechanical strength and shape holding capability enables the preparation of the face mask in a unique 3D shape that extends from the nose bridge to the chin, leaving an air gap between the mouth and the inner layer of the face mask. Design advantage obtained by the incorporation of the PET layer enables smooth facial movements and hindrance free speaking. The 3D folding feature of the mask is seamless and fits snug on the user's face that which prevents spectacle fogging and chances of infections.

IPC Classes  ?

• A41D 13/11 - Protective face masks, e.g. for surgical use, or for use in foul atmospheres
• B01D 61/14 - UltrafiltrationMicrofiltration
• B01D 63/10 - Spiral-wound membrane modules

Abstract

The present disclosure relates to a hydrophilic composite, comprising 2nd bimetallic component M3M4 (e.g. CoMoO4) deposited on 1st bimetallic component M1M2 (e.g. NiMoO4), supported on a support (e.g. Ni foam) (also termed as M3M4Oy@M1M2Ox/support); wherein the composite has dual structural property without the need of binder/additive and to a process of preparing the hydrophilic composite (M3M4Oy@M1M2Ox/support) and uses thereof. The present disclosure also relates to the environmentally benign production of green hydrogen through HER (hydrogen evolution reaction), and OER (oxygen evolution reaction) reactions using M3M4Oy@M1M2Ox/support as cathode or anode or both.

IPC Classes  ?

• B01J 23/75 - Cobalt
• B01J 23/755 - Nickel
• B01J 23/745 - Iron
• B01J 23/84 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups with arsenic, antimony, bismuth, vanadium, niobium, tantalum, polonium, chromium, molybdenum, tungsten, manganese, technetium or rhenium
• C25B 1/04 - Hydrogen or oxygen by electrolysis of water

Abstract

Utilization of CO2 for the alkylation of aromatic hydrocarbons is one of the green and sustainable routes for the production of valuable alkylated aromatics like xylenes. Aspects of the present invention deal with the development of single-step catalytic process for the production of alkylated aromatics using CO2 as a carbon source and alkylation reagent and methylcyclohexane as a hydrogen atom donor as well as source of toluene. In presence of the metal functionalized zeolite catalyst, methylcyclohexane undergoes dehydrogenation to produce toluene and hydrogen; hydrogen reacts with CO2 to form active alkylating species which triggers the alkylation of toluene. Additionally, a novel process is disclosed for the production of xylene-rich alkylated aromatics from methylcyclohexane and CO2 using single multi-functional catalyst possessing dehydrogenation, hydrogenation and acid functionalities.

IPC Classes  ?

• C07C 2/72 - Addition to a non-aromatic carbon atom of hydrocarbons containing a six-membered aromatic ring
• B01J 23/652 - Chromium, molybdenum or tungsten
• B01J 37/04 - Mixing
• B01J 37/08 - Heat treatment
• C07C 15/04 - Benzene
• C07C 15/06 - Toluene
• C07C 15/08 - Xylenes

Abstract

The technology described herein discloses a non-isolated multiport dc-dc converter with three input dc ports to integrate three different energy sources namely fuel cell, battery and ultracapacitor, and two dedicated output ports for traction load and auxiliary loads, respectively. The invented system is capable of providing high flexibility in power flow management among the three energy sources, corresponding to diverse dynamic load power events encountered in an EV. Besides, the system exhibits prominent features like simultaneous and bidirectional power transferring capability between the multiple dc ports and single stage power processing in every possible power flow scenarios. Furthermore, the technology embodies distinct operating modes depending upon the dynamic load power variations and state of voltage levels of the energy sources. Nevertheless, the technology aims at improving the utilization efficiency of the energy storage system by maneuvering power flows between multiple dc ports, thereby augmenting the overall performance of EV powertrain.

IPC Classes  ?

• H02M 3/158 - Conversion of DC power input into DC power output without intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode using devices of a triode or transistor type requiring continuous application of a control signal using semiconductor devices only with automatic control of output voltage or current, e.g. switching regulators including plural semiconductor devices as final control devices for a single load
• B60L 1/00 - Supplying electric power to auxiliary equipment of electrically-propelled vehicles
• B60L 15/00 - Methods, circuits or devices for controlling the propulsion of electrically-propelled vehicles, e.g. their traction-motor speed, to achieve a desired performanceAdaptation of control equipment on electrically-propelled vehicles for remote actuation from a stationary place, from alternative parts of the vehicle or from alternative vehicles of the same vehicle train
• B60L 50/40 - Electric propulsion with power supplied within the vehicle using propulsion power supplied by capacitors
• B60L 50/75 - Electric propulsion with power supplied within the vehicle using propulsion power supplied by batteries or fuel cells using propulsion power supplied by both fuel cells and batteries
• H02J 7/34 - Parallel operation in networks using both storage and other DC sources, e.g. providing buffering
• H02M 1/14 - Arrangements for reducing ripples from DC input or output

Abstract

222S gases.

IPC Classes  ?

• B01J 35/00 - Catalysts, in general, characterised by their form or physical properties
• B01J 23/30 - Tungsten
• C01G 41/02 - OxidesHydroxides

Abstract

The present invention discloses a 3D rigid mesoporous honeycomb boron carbon nitride (HBCN) nanomaterial as a host for plating/depositing metal. Said nanomaterial plated/deposited with metal is used as metal anode in alkali metal ion battery.

IPC Classes  ?

• H01M 4/66 - Selection of materials
• B82Y 40/00 - Manufacture or treatment of nanostructures
• H01M 4/02 - Electrodes composed of, or comprising, active material
• H01M 4/04 - Processes of manufacture in general
• H01M 4/38 - Selection of substances as active materials, active masses, active liquids of elements or alloys
• H01M 4/58 - Selection of substances as active materials, active masses, active liquids of inorganic compounds other than oxides or hydroxides, e.g. sulfides, selenides, tellurides, halogenides or LiCoFySelection of substances as active materials, active masses, active liquids of polyanionic structures, e.g. phosphates, silicates or borates
• H01M 4/78 - Shapes other than plane or cylindrical, e.g. helical
• H01M 4/80 - Porous plates, e.g. sintered carriers
• H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries
• H01M 10/0567 - Liquid materials characterised by the additives
• H01M 10/0568 - Liquid materials characterised by the solutes
• H01M 10/0569 - Liquid materials characterised by the solvents

Abstract

The present invention provides a reactor for the anaerobic digestion of lignocellulosic biomass for biogas and biomanure (digestate) generation. The innovation is designed primarily for the treatment of lignocellulosic biomass such as rice straw/rice husk with a total solids consistency in the slurry between 20 - 40 %. One of the major obstacles in the AD of lignocellulosic biomass is the formation of scum layer on the top surface of the slurry with the fibrous material leading to choking of pipelines. Scum layer formation occurs due to the phase separation of the material into solid and liquid, poor contact between the organic matter and the microorganisms, low heat and mass transfer. Phase separation of solid and liquid occurs particularly in low density materials such as lignocellulosic biomass. Therefore, the reactor is designed in a way that the maximum solids including the fibrous material is retained inside the reactor for efficient digestion. The reactor comprises of a feed hydrolysis duct situated inside the reactor. The hydraulic residence time of the feed hydrolysis duct is delinked with that of the main reactor. Further the reactor is provided with open and closed, perforated cones to ensure efficient movement of the slurry from the top to bottom. Pressurized biogas purging in the bottom elongated cone area of the reactor ensures no settling of solids in the cone, while the slurry recirculation and the pressurized biogas purging inside the digester helps promote efficient mixing of the reactor contents in the digester preventing the formation of phase separation, scum layer formation, choking etc. The feed slurry is initially allowed to flow through the central duct towards the bottom of the reactor which then expands creating an upward flow regime from the bottom due to the presence of a truncated cone. The perforated truncated cones ensure retainment of maximum solids in the reactor arresting any biomass washout. The reactor is also facilitated with a feed preparation system, digestate collection tank, biogas balloon, feed inlet and digestate outlet valve mechanism for controlled feed in and digestate out.

IPC Classes  ?

• C02F 3/28 - Anaerobic digestion processes
• C02F 11/04 - Anaerobic treatmentProduction of methane by such processes

Abstract

The present disclosure relates to a a method of modulating the activity of EHMT1 N/Cand its role as a pro-viral factor at the interface of host-virus interactions. The present disclosure also relates to a method of inhibiting/reducing viral replication, use of molecules targeting EHMT1 N/C for inhibiting viral replication for treating viral infection, a method of treating viral infection and a method/platform for screening anti-viral agents/molecules.

IPC Classes  ?

• A61K 31/517 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
• A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
• A61P 31/12 - Antivirals
• A61P 31/14 - Antivirals for RNA viruses
• C12N 9/10 - Transferases (2.)

Abstract

The present invention relates to functionalized Maleimides and Isomaleimides of general Formula (I) and a process for the preparation thereof, involving [3+2] annulation of α,β-unsaturated aldehydes with carbamoyl alkylates via an enolate pathway to afford highly functionalized compounds of Formula (I); The present invention relates to functionalized Maleimides and Isomaleimides of general Formula (I) and a process for the preparation thereof, involving [3+2] annulation of α,β-unsaturated aldehydes with carbamoyl alkylates via an enolate pathway to afford highly functionalized compounds of Formula (I);

IPC Classes  ?

• C07D 207/444 - Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5
• A61K 31/341 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
• A61K 31/4015 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
• C07D 207/44 - Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members
• C07D 307/66 - Nitrogen atoms

Abstract

The present invention discloses a novel flash sintering process for synthesis of MAX phases, namely, but not limited to Ti2SnC and Ti3SiC2 in an extremely short time. The process is a combustion synthesis where a relatively low voltage in a range of 20-60 V/cm is applied using a DC/AC power source across the compact precursor material prior to ignition. The flash event is observed with a quick rise in current flow in a range of 100-300 mA/mm2 followed by measured temperature range of 1200-1400° C. in a green compact body of different MAX phase compositions. The process of the present invention enables the synthesis of MAX phases in air by suppressing oxidation of the material because of the very short residence time of the flashing event. In addition, the present invention focuses on synthesis of MAX phase in bulk to serve as the starting material for the development of two-dimensional MXenes.

IPC Classes  ?

• C04B 35/56 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on carbides
• C04B 35/626 - Preparing or treating the powders individually or as batches
• C04B 35/65 - Reaction sintering of free metal- or free silicon-containing compositions

Abstract

A three degrees of freedom (3DoFs) Wedge Air Bearing Translational Stage System (WABSS) for positioning of miniature components using a parallel kinematic mechanism. The system has three kinematic sub-chains situated at 120° apart from each other, where each sub-chain has one prismatic joint and one planar joint guided by air bearings. One central stage assembly (CSA) having three wedges with wedge planes oriented 45° to the horizontal plane is capable of translations along the X-, Y- and Z-axes for precision positioning of the targeted workpiece material held on the CSA. Following the parallel kinematic principle, the coordinated translations of the three slide bars produce 3DoFs translations to position CSA in each sub-chain. The linear geometric error along the Z-axis is independent from the angular tolerances due to its unique vertical structure.

IPC Classes  ?

• F16M 11/20 - Undercarriages with or without wheels
• F16C 32/06 - Bearings not otherwise provided for with moving member supported by a fluid cushion formed, at least to a large extent, otherwise than by movement of the shaft, e.g. hydrostatic air-cushion bearings

Abstract

This invention provides a process for the preparation of orthogonally protected ribose derivative. Which are further used as donor for the synthesis of N4-hydroxy cytidine and its derivatives by using commercially available materials under very mild reaction condition and short period of time. Thereafter N-hydroxylation of cytidine can be achieved in a short period of time. The intermediates or the final compounds thus obtained can be used for the treatment of viral infections.

IPC Classes  ?

• C07H 19/067 - Pyrimidine radicals with ribosyl as the saccharide radical

Abstract

A DVET unit is disclosed that comprises a first syringe and a second syringe having a first plunger and a second plunger, adapted to execute a backward stroke and a forward stroke in the respective syringe. The DVET unit also includes a first valve and a second valve. Further, the first valve is closed and the second valve is opened to draw blood from the source and the specimen into the first syringe and the second syringe. Moreover, the first valve is opened and the second valve is closed to pump the blood, drawn during the backward stroke, from the first syringe and the second syringe into the specimen and the waste bin.

IPC Classes  ?

• A61M 5/142 - Pressure infusion, e.g. using pumps
• A61M 5/14 - Infusion devices, e.g. infusing by gravityBlood infusionAccessories therefor
• A61M 5/145 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons
• A61M 5/168 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters

Abstract

The present invention relates to 5,6-diaryl-5,6-diazaspiro [2.4] heptane-4,7-dione compound of formula (I) and the process of preparation thereof. The present invention also relates to the compound of formula (I) and its use in the preparation of sulfinpyrazone uricosuric drug or its derivatives/analogues. The compound of formula (I) is useful as anti-malarial, anti-microbial, anti-bacterial, anti-inflammatory, COX-2 inhibition, and anti-analgesics agents. Formula (I)

IPC Classes  ?

• C07D 231/54 - Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
• C07D 247/00 - Heterocyclic compounds containing rings having two nitrogen atoms as the only ring hetero atoms, according to more than one of groups
• C07C 13/04 - Monocyclic hydrocarbons or acyclic hydrocarbon derivatives thereof with a three-membered ring
• C07D 471/10 - Spiro-condensed systems
• A61P 19/06 - Antigout agents, e.g. antihyperuricemic or uricosuric agents
• A61P 7/10 - Antioedematous agentsDiuretics

Abstract

A Bidirectional, Linear and Binary, Segmented Antagonistic Servomechanism-based Shape Memory Alloy (SMA) Actuator comprising a main stroke transmitting lever (11 or 18) and a plurality of part-modules (15A or 15B) disposed in a closely spaced arrangement and adapted to undergo a reciprocal translation in a first direction. wherein, the part-modules comprising a plurality of segments having SMA elements (12). The invention provides two configurations arranged in ‘straight’ and ‘cross’ configurations of the SMA elements in the part-modules. Further above configuration are arranged in a tight close space however, the “cross” configuration provides additional 40% compactness. The configurations comprise a “S-type long tail” or “flipped F-type long tail” main stroke transmitting lever and plurality of “straight” or “cross” configurations part modules, respectively. The novel embodiment can be utilized for micro-positioning of 3D printer filament extruder head, linear and angular displacement applications such as robotic, prosthesis, bi-stable position control, latching-unlatching systems, and other wide engineering applications.

IPC Classes  ?

• F03G 7/06 - Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for using expansion or contraction of bodies due to heating, cooling, moistening, drying, or the like
• B33Y 30/00 - Apparatus for additive manufacturingDetails thereof or accessories therefor

Abstract

The present invention discloses a process for the hydrogenation of imines of Formula I by palladium-based catalyst to provide product of Formula II with more than 95% conversion of substrate and more than 95% of desired hydrogenated product. The present invention discloses a process for the hydrogenation of imines of Formula I by palladium-based catalyst to provide product of Formula II with more than 95% conversion of substrate and more than 95% of desired hydrogenated product.

IPC Classes  ?

• C07D 213/42 - Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
• B01J 23/44 - Palladium
• B01J 27/138 - HalogensCompounds thereof with alkaline earth metals, magnesium, beryllium, zinc, cadmium or mercury
• B01J 27/185 - PhosphorusCompounds thereof with iron group metals or platinum group metals
• B01J 37/03 - PrecipitationCo-precipitation
• B01J 37/08 - Heat treatment

Abstract

The present invention relates to a carrier system for agrochemicals. Specifically, the present invention relates to a carrier system based on nanocomposites comprising double encapsulated nanocomposite composition for staged delivery of a growth stimulant for a weed and a herbicide for controlling the same. The encapsulation of active ingredients is designed in such a way that growth stimulant is released initially to induce the germination of the weed and then, the herbicides to kill them during the emergence. The present invention also relates to a method of producing the double encapsulated nanocomposite granules and uses thereof.

IPC Classes  ?

• A01N 25/12 - Powders or granules
• A01N 25/10 - Macromolecular compounds
• A01N 33/00 - Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
• A01N 35/00 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
• A01N 37/00 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids

Abstract

The present disclosure relates to a recombinant vector. Particularly, the present disclosure relates to a recombinant vector to overexpress 4-coumarate Co-enzyme A ligase 11 gene (4CL11) in plant cells. Further, the present disclosure relates to a binary expression vector comprising a pRI101AN vector with the 4CL11 ORF sequence from Ocimum kilimandscharicum and regulatory elements for overexpressing host 4CL11 gene in plant cells, which results in the accumulation of flavonoids (kaempferol and quercetin as well as their glycoside derivatives), altered lignin content, increased natural product biosynthesis that eventually leads to reduced auxin levels and decreased expression of auxin transport and signaling genes, causing reduced root growth.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• C12N 15/84 - Ti-plasmids
• C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants

Abstract

The present disclosure is directed to a catalyst for carbon dioxide to methanol conversion comprising: 1-10 wt % of Nickel; 5-15 wt % of Zinc; and 80-95 wt % of metal oxide, wherein the wt % is based on the total weight of the catalyst. The present disclosure also provides a method for preparation of a catalyst for carbon dioxide to methanol conversion comprising: i) dissolving 1-10 wt % nickel precursor and 5-15 wt % zinc precursor in a solvent to obtain a first mixture; ii) adding 80-95 wt % metal oxide in the first mixture as obtained in step (a) to obtain a second mixture; iii) evaporating the solvent from the second mixture as obtained in step (b), drying and calcining in air at a temperature in the range of 350° C. to 500° C. for a period in the range of 2 hr to 4 hrs to obtain calcined mixture; and iv) reducing the calcined mixture as obtained in step (c) under hydrogen atmosphere at a temperature in the range of 500° C. to 700° ° C. for a period in the range of 1 hr to 3 hrs to obtain the catalyst. The disclosure also provides a low pressure process for conversion of carbon dioxide to methanol.

IPC Classes  ?

• B01J 23/80 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups with zinc, cadmium or mercury
• B01J 21/04 - Alumina
• B01J 21/06 - Silicon, titanium, zirconium or hafniumOxides or hydroxides thereof
• B01J 35/30 - Catalysts, in general, characterised by their form or physical properties characterised by their physical properties
• B01J 37/02 - Impregnation, coating or precipitation
• B01J 37/04 - Mixing
• B01J 37/08 - Heat treatment
• B01J 37/18 - Reducing with gases containing free hydrogen
• C07C 29/156 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of oxides of carbon exclusively with hydrogen or hydrogen-containing gases characterised by the catalyst used containing iron group metals, platinum group metals, or compounds thereof

Abstract

The present invention provides a process for the fabrication of a flexible strain and pressure sensor using a synergistic composition of ZnO nanoparticle and graphene nanoplatelets. The substrate used is PDMS, a polymer that imparts the desired properties of flexibility and durability to the sensor. The invention also discloses a simple and facile process of sensor fabrication, wherein the sensing element is embedded in the substrate material, and thereby prevents any deformation or peeling even after repeated stretch/release cycles. The reported flexible sensors can replace the conventional stiff sensors due to their ability to be contoured on curved surfaces, such as body parts. These sensors can find applications in wearable electronics and can have myriad of uses in healthcare monitoring, human-machine interface, electronic skin on prosthetics, and so on.

IPC Classes  ?

• H10N 30/077 - Forming of piezoelectric or electrostrictive parts or bodies on an electrical element or another base by depositing piezoelectric or electrostrictive layers, e.g. aerosol or screen printing by liquid phase deposition
• H10N 30/02 - Forming enclosures or casings
• H10N 30/06 - Forming electrodes or interconnections, e.g. leads or terminals
• H10N 30/081 - Shaping or machining of piezoelectric or electrostrictive bodies by coating or depositing using masks, e.g. lift-off
• H10N 30/092 - Forming composite materials
• H10N 30/30 - Piezoelectric or electrostrictive devices with mechanical input and electrical output, e.g. functioning as generators or sensors

Abstract

The present disclosure relates to a dibenzhydryl substituted napthoxy imine ligated metal catalyst compound of formula (I) and their use in alkene (co)polymerization and oligomerization. The present invention also relates to a process for preparing the dibenzhydryl substituted napthoxy imine ligated metal catalyst compound of formula (I) and to a process of polymerization of alkene using the catalyst compound of formula (I). The present invention is able to provide a novel metal catalyst compounds that reduces chain transfer and increase the activity in alkene polymerization and oligomerization reactions.

IPC Classes  ?

• C08F 4/70 - Iron group metals, platinum group metals, or compounds thereof
• B01J 31/18 - Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes containing nitrogen, phosphorus, arsenic or antimony

Abstract

The present invention discloses a thermostable system 100 for storage and transportation of hot goods, especially of food items. The said system combines an insulation container 102 made of biodegradable polyurethane with a novel phase change material to provide improved holding time and temperature ranges. With the thermostable system set-forth by the present invention, 10-14 hours of holding time in the range of 45-70°C was achieved.

IPC Classes  ?

• B65D 81/38 - Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents with thermal insulation

Abstract

The compound IIIM-152 and its derivatives have been reported as potent stem cell modulators by down-regulating beta-catenin signalling. TNBCs are highly aggressive cancers and chemotherapy remains one of the primary treatment options. However, CSCs remains non-responsive to the Paclitaxel treatment leads to disease recurrence and metastasis and is one of the major clinical challenges. The Combinatorial treatment of IIIM eliminates the Paclitaxel Resistant Cancer Stem Cells, whereas Paclitaxel only treatment is unable to target CSCs subpopulation. Similarly, a combination of Paclitaxel-IIIM152, showed significant reduction in tumor burden and decrease in number of CSCs in excised tumours. The combination of IIIM-152 and Paclitaxel proves to be clinically efficacious in treating the Paclitaxel non-responsive highly aggressive residual cancer stem cells to achieve long lasting treatment. The invention also provides a method for preparing the composition comprising Paclitaxel and IIIM-152.

IPC Classes  ?

• A61K 31/4174 - Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
• A61K 31/337 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
• A61K 47/20 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
• A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters

Abstract

The present invention discloses a process for extracting biomolecules from biomass using an extraction apparatus. Further, the present invention provides an ultrasonic process that extracts lutein pigments from marigolds using an extraction apparatus that requires at least two repeating units of reactor setup. Here the present invention shows an extraction efficiency in the range of 95-100% and purity of biomolecules with a range of 90-95% under mild reaction conditions.

IPC Classes  ?

• B01D 11/02 - Solvent extraction of solids

Abstract

The present invention relates to a supported multimetallic catalyst system comprising metallic mixture of nickel and gold; or nickel, gold and indium fortuning and enhancing selectivity in hydrogenation of carbon dioxide, and a method of synthesizing the same. The present invention further relates to a method of hydrogenation of carbon dioxide into CO and methane via RWGS (tri-metallic catalyst) and methanation (bimetallic catalyst) reactions respectively at lower temperatures and ambient pressure and lighter alcohols (methanol) at high pressure and temperature (tri-metallic catalyst), respectively, using said supported multimetallic catalyst system.

IPC Classes  ?

• B01J 23/755 - Nickel
• B01J 23/52 - Gold
• B01J 23/08 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of gallium, indium or thallium

Abstract

The present invention discloses a thermostable system (100) for storage and transportation of perishable goods in cold-chains, especially of food items. The said system combines an insulation container (102) made of biodegradable polyurethane with a cooling solution. Given polyurethane's hydrophilic nature and softer texture, a commercially-sourced damp-proof, lightweight, and food-grade coating is applied to the insulation container (102), offering enhanced water-resistance, easier handling, and extended holding-time. The system (100) further comprises a double-walled trough (112) to hold the goods to be stored/transported and the cooling solution can be filled into the hollow spaces between the inner and outer walls of the said trough. The cooling solution consists of 30% w/v Polyethylene Glycol (PEG)-4000 in water and when used in conjunction with the insulation container (102), enable the thermostable system (100) to sustain a 2-15°C temperature range for 60 to 100 hours.

IPC Classes  ?

• F25D 3/08 - Movable containers portable, i.e. adapted to be carried personally
• F25D 23/06 - Walls

Abstract

The present invention describes the development of a novel, tumor epithelial cell and tumor-associated macrophage (TAM)-targeting, blood brain barrier (BBB) crossing glucose-based nanospheres (CSP). More specifically, the present invention discloses a nanoformulation and/or a composition having anticancer activity comprising of carbon nanosphere (CSP) and a sigma receptor targeting ligand (H8) in the ratio of 1:0.08 to 1:0.2, a complex prepared thereof, a process for preparation thereof and a kit for delivery of the drug molecule or the formulation or the composition to tumor site.

IPC Classes  ?

• A61K 31/4515 - Non-condensed piperidines, e.g. piperocaine having a butyrophenone group in position 1, e.g. haloperidol
• A61K 47/68 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
• A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
• A61P 35/00 - Antineoplastic agents

Abstract

The present invention relates to AB2O4 type mixed metal oxide catalyst system having spinel/inverse spinel structure with support. The present invention also relates to the process for preparation of mixed metal oxide catalyst system. More particularly, the present invention relates to a process for the partial oxidation of alkanes to value added products and corresponding oxygenates by using said AB2O4 type mixed metal oxide catalyst with support(s).

IPC Classes  ?

• B01J 23/26 - Chromium
• B01J 23/34 - Manganese
• B01J 23/72 - Copper
• B01J 23/74 - Iron group metals
• B01J 23/745 - Iron
• B01J 23/75 - Cobalt
• B01J 35/60 - Catalysts, in general, characterised by their form or physical properties characterised by their surface properties or porosity
• B01J 35/61 - Surface area
• B01J 35/64 - Pore diameter
• B01J 37/00 - Processes, in general, for preparing catalystsProcesses, in general, for activation of catalysts

Abstract

The present invention is directed towards a process of RT-PCR based diagnosis of SARS-CoV2 and other related respiratory viruses without storing and transporting the naso-pharyngeal and oro-pharyngeal swabs in Viral Testing Media directly after extracting the viral particles from the swabs in a suitable buffer, and using these extracts directly, without involving any steps of RNA isolation/extraction, for RT-PCR based diagnosis of SARS-CoV2. The present invention is also directed towards kits for time and cost-efficient diagnosis of SARS-CoV2 and other related respiratory viruses at efficacies matching or better than the efficacies of the gold-standard RT-PCR method starting from VTM transported swabs for diagnosing the same. The present invention also directs to variant process wherein the viral particles eluted in suitable buffers are further subjected to the conventional steps of RNA extraction before qRT-PCR.

IPC Classes  ?

• C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage

Abstract

The present invention discloses a continuous process for the synthesis of dimethyl carbonate from methanol and carbon dioxide over a ceria-based mixed metal oxide-silica catalyst formulation in the presence of a dehydrating or water trapping compound (2-Cyanopyridine).

IPC Classes  ?

• C07C 68/04 - Preparation of esters of carbonic or haloformic acids from carbon dioxide or inorganic carbonates
• B01J 23/10 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of rare earths
• B01J 35/02 - Solids
• B01J 35/10 - Solids characterised by their surface properties or porosity
• B01J 37/04 - Mixing
• B01J 37/06 - Washing
• B01J 37/08 - Heat treatment

Abstract

Antimony doped tin oxide-polypyrrole nano-composites for in situ and ex situ ppm level ammonia gas sensing at very low temperatures (room temperature to sub-zero ° C.). During synthesis, hydrogen peroxide (H2O2) has been used as a novel template for simultaneous oxidative polymerization of pyrrole as well as the polymer loading on doped metal oxide base. Usability of the above composition was tested for ppm level in-situ and ex-situ ammonia gas sensing in a very low temperature range (room temperature to −30° C.). Stable and highly selective responses to ammonia gas were recorded in situ and ex situ at the very low temperature range (room temperature to −30° C.). The revelation of very low temperature ammonia sensing property by the antimony doped tin oxide-polypyrrole nano-composite could be used for detecting meat and meat product spoilage under in situ and ex situ refrigerated conditions for cold storages and commercial preservations.

IPC Classes  ?

• G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups

Abstract

Triple G-C-T base coded nucleobase amino acids according to Formula (I): Triple G-C-T base coded nucleobase amino acids according to Formula (I): wherein R is —H or -Boc, are provided as building blocks for peptide sequences. The compound of formula (I) includes three recognition sites, DDA (G mimic), DAA (C mimic) and ADA (T mimic) that can simultaneously interact with two sets of nucleobases (C-A or G-A), at any given time. A one-step synthetic process for the triple G-C-T base coded nucleobase amino acids is provided.

IPC Classes  ?

• C07K 1/02 - General processes for the preparation of peptides in solution
• C07K 1/06 - General processes for the preparation of peptides using protecting groups or activating agents

Abstract

The present disclosure provides a switched reconfigurable multi-converter multi-source energy storage system configuration for electrified vehicles comprising of multiple dc/dc power converters, multiple energy sources, a mode selector switching module further comprising a plurality of controllable switches and a controller. A method of switching to reconfigure the multi-converter multi-source energy storage system during the dynamic events of variable power demand or regeneration in an electrified vehicle is disclosed. Furthermore, a power flow control scheme for executing the dynamic switching methods of reconfiguration to maneuver the flow of power within the system during different scenarios of forward power delivery or reverse power accumulation is disclosed. The controllable switches are methodically activated or deactivated to couple or decouple the energy sources to or from the input side of the dc/dc power converters by means of necessary activation or deactivation signals from the controller. Nevertheless, a fault tolerant control scheme is disclosed to ensure fail-safe operation of the switched reconfigurable system during the occurrence of fault in any of the dc/dc power converters.

IPC Classes  ?

• H02J 3/32 - Arrangements for balancing the load in a network by storage of energy using batteries with converting means
• B60L 50/60 - Electric propulsion with power supplied within the vehicle using propulsion power supplied by batteries or fuel cells using power supplied by batteries
• B60L 55/00 - Arrangements for supplying energy stored within a vehicle to a power network, i.e. vehicle-to-grid [V2G] arrangements
• H02J 3/00 - Circuit arrangements for ac mains or ac distribution networks
• H02J 3/38 - Arrangements for parallelly feeding a single network by two or more generators, converters or transformers
• H02M 3/335 - Conversion of DC power input into DC power output with intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode to produce the intermediate AC using devices of a triode or a transistor type requiring continuous application of a control signal using semiconductor devices only

Abstract

A Janus G-C base as building block for a triazine based self-assembly of formula (I), a process for the preparation, and its application in developing supramolecular polymers, peptide nucleic acids (PNAs) and smart polymers thereof. A triazine based self-assembly of formula (I): A Janus G-C base as building block for a triazine based self-assembly of formula (I), a process for the preparation, and its application in developing supramolecular polymers, peptide nucleic acids (PNAs) and smart polymers thereof. A triazine based self-assembly of formula (I): wherein, ‘R’ is selected from the group comprising of linear or branched unsubstituted and substituted C1-C7 alkyl, unsubstituted and substituted aryl, unsubstituted and substituted natural amino acids which may be protected, linear or branched unsubstituted and substituted C1-C7 alcohols, or linear or branched unsubstituted and substituted C1-C7 amines.

IPC Classes  ?

• C07D 251/46 - One nitrogen atom with oxygen or sulfur atoms attached to the two other ring carbon atoms
• C08F 116/14 - Monomers containing only one unsaturated aliphatic radical
• C08F 120/34 - Esters containing nitrogen
• C08F 120/60 - Amides containing nitrogen in addition to the carbonamido nitrogen

Abstract

The present invention realtes to a process for the detoxification and concentration of xylose rich biomass derived liquid hydrolysate and its application as a substrate for the synthesis of crystalline and pure xylitol.

IPC Classes  ?

• C12P 7/18 - Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric

Abstract

2222.

IPC Classes  ?

• C01B 39/22 - Type X
• B01D 53/02 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by adsorption, e.g. preparative gas chromatography

Abstract

The present invention discloses a cationic lipid-based formulation for in vivo delivery of nucleic acid. The present invention describes the development of a lipid system that can induce efficient non-viral delivery of nucleic acid, especially RNA, for the purpose of efficient nucleic acid transfection toward eliciting vaccination in vivo. Present invention provides a lipid/RNA complex (lipoplex) formulation having sufficiently long shelf life that performs without any compromise in its transfection output. The present invention further provides cationic lipid- based formulations for RNA delivery with maximum nucleic acid complexation ability and with comparatively lesser amount of cationic lipid having higher stability.

IPC Classes  ?

• A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
• A61P 31/12 - Antivirals
• A61K 39/12 - Viral antigens
• A61K 31/7105 - Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides

Abstract

The present invention relates to a method for fabrication of blue-fluorescent and non-toxic nanodiamonds from atmospheric particulate matters including total solid suspended particulate matter (TSPM) and particulate matter with size less than 10μ (PM10). Mostly, the present invention provides an efficient mitigation process for particulate pollutant by conversion of these pollutants (PM and TSPM) into non-toxic high-value product such as nanodiamond by using the ultrasonic-assisted chemical oxidation method. This method is environmental friendly, simple, and biocompatible for the production of nanodiamonds from such atmospheric particulate matter.

IPC Classes  ?

• C01B 32/26 - Preparation
• C01B 32/28 - After-treatment, e.g. purification, irradiation, separation or recovery
• C09K 11/01 - Recovery of luminescent materials
• C09K 11/65 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing inorganic luminescent materials containing carbon
• B09B 3/00 - Destroying solid waste or transforming solid waste into something useful or harmless

Abstract

The present invention relates selective for Kappa opioid receptor (KOR) agonist compounds, their tautomeric forms, their pharmaceutically accepted salts, or prodrugs thereof, which are useful for the treatment or prevention of various diseases in which the KOR are implicated, such as treatment of prevention of neuropathic pain, visceral pain, drug addiction, hyperalgesia, arthritic inflammation or autoimmune inflammation. The invention also relates to a process for the manufacture of said compounds and pharmaceutical compositions containing them and their use.

IPC Classes  ?

• C07D 471/04 - Ortho-condensed systems
• A61P 251/04 -

Abstract

The present invention relates to sophorolipid based calcium phosphate nano-particles composition and a process for preparing the same. The invention thus provides a composition of calcium phosphate nano-particles having enhanced biocompatible, bioresorbable, osteoconductive and osteoinductive properties.

IPC Classes  ?

• A61K 9/51 - Nanocapsules
• C01B 25/32 - Phosphates of magnesium, calcium, strontium, or barium
• C12P 7/64 - FatsFatty oilsEster-type waxesHigher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl groupOxidised oils or fats
• C12P 7/6409 - Fatty acids

Abstract

Functionalized benzocycloheptenes are one of the most important classes of bicyclic framework that have been investi-gated in different areas of biological activities. The claimed invention provides preparations of benzocycloheptene analogues, inhibitors of PI3K and MK2, pharmaceutical compositions containing them and their use in therapy. The compounds of Formula I, II, III, IV, V and VI may be used as anti type 2 diabetes, antipyretic, anti-inflammatory, antiepileptic, anticancer, antiulcer, CNS-stimulant, and CNS-depressant. These benzocycloheptene derivatives are useful in treatment of PI3K and MK2 related disorders.

IPC Classes  ?

• C07D 209/94 - [b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
• C07C 311/16 - Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
• C07D 307/93 - Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
• C07D 221/18 - Ring systems of four or more rings
• C07C 317/14 - SulfonesSulfoxides having sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings
• C07C 317/10 - SulfonesSulfoxides having sulfone or sulfoxide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings

Abstract

The present invention provides a carbon-free electrocatalyst for oxygen reduction reaction (ORR) in polymer electrolyte membrane fuel cells (PEMFCs). Described herein is a Pt decorated carbon-free catalyst with solid-state proton conducting zirconium phosphate (ZrP) as support material for PEMFC. The invention further describes the process for obtaining said Pt decorated conducting zirconium phosphate (ZrP) as support material as proton conductor. Also, the present invention relates to an efficient proton conductor which optimizes utilization of Pt- catalyst thereby improving the performance of the PEMFC. The carbon-free system alleviates the problem of carbon-corrosion leading to detachment of Pt-nanoparticles.

IPC Classes  ?

• H01M 8/00 - Fuel cellsManufacture thereof
• H01M 4/92 - Metals of platinum group

Abstract

Compounds having Structure I are provided for treating diseases and disorders for which inhibition or modulation of the Ubiquitin Ligase COP1 enzyme produces a physiologically beneficial response, in particular for the treatment of Non-Alcoholic Fatty Liver Disease (NAFLD). These compounds having Structure I are capable of increasing the level of adipose triglyceride lipase (ATGL). Also provided is the process of preparing compounds having Structure I. Compounds having Structure I are provided for treating diseases and disorders for which inhibition or modulation of the Ubiquitin Ligase COP1 enzyme produces a physiologically beneficial response, in particular for the treatment of Non-Alcoholic Fatty Liver Disease (NAFLD). These compounds having Structure I are capable of increasing the level of adipose triglyceride lipase (ATGL). Also provided is the process of preparing compounds having Structure I.

IPC Classes  ?

• C07D 239/91 - Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
• C07D 413/12 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
• C07D 401/04 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring- member bond
• C07D 403/04 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings directly linked by a ring-member-to-ring- member bond

Abstract

The present invention relates to the beneficial effect of Chebulinic acid (CA) and its enriched standardized fraction (CAEF) isolated/prepared from the fruits of Terminalia chebula for the management of Benign Prostatic Hyperplasia respectively. Further, it relates to a novel, convenient and economically viable method for the isolation of chebulinic acid (CA) and ellagic acid (EA) from the dried and powdered fruits of T. chebula without using any expensive and tedious chromatographic techniques such as HPLC, column chromatography, resins etc.

IPC Classes  ?

• A61K 36/185 - Magnoliopsida (dicotyledons)
• A61K 31/366 - Lactones having six-membered rings, e.g. delta-lactones
• A61K 9/107 - Emulsions
• A61K 47/12 - Carboxylic acidsSalts or anhydrides thereof
• A61K 47/26 - Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharidesDerivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
• A61K 47/44 - Oils, fats or waxes according to two or more groups of Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
• A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
• A61P 13/08 - Drugs for disorders of the urinary system of the prostate

Abstract

The present invention relates to 5-methyl substituted furan compounds of general formula (I) and process for the preparation thereof: ORlR2 R3CH3(1) Particularly, the present invention relates to a metal catalyst and hydrogen gas free, atom-economy, highly selective and low-cost process for the preparation of methyl substituted furan compounds from different aldehyde substituted furan compounds.

IPC Classes  ?

• C07D 307/48 - Furfural
• C07D 307/36 - Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
• C11C 3/12 - Fats, oils or fatty acids obtained by chemical modification of fats, oils or fatty acids, e.g. by ozonolysis by hydrogenation

Abstract

An effcient one step, one pot process of synthesis of value added products such as diols, monools and/or acids, preferably 1,2-PG from sugars/polysachhrides is disclosed. The process is catalyzed by a bimetallic catalyst supportted on alumina and the catalyst is recyclable. The process of synthesis of the catalyst is a simple process and it converts a high % of the substrates to the desired polyols under mild conditions.

IPC Classes  ?

• B01J 21/04 - Alumina
• B01J 21/12 - Silica and alumina
• B01J 21/18 - Carbon
• B01J 23/28 - Molybdenum
• B01J 23/755 - Nickel
• B01J 23/88 - Molybdenum
• B01J 23/883 - Molybdenum and nickel
• C07C 27/04 - Processes involving the simultaneous production of more than one class of oxygen-containing compounds by reduction of oxygen-containing compounds
• C07C 29/132 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen-containing functional group
• C07C 31/10 - Monohydroxylic acyclic alcohols containing three carbon atoms
• C07C 31/12 - Monohydroxylic acyclic alcohols containing four carbon atoms
• C07C 31/20 - Dihydroxylic alcohols

Abstract

The present invention relates to Na-ion batteries comprising honey comb boron carbon nitride (HBCN) as an anode. More particularly, the present invention relates to half-cell and full cell 5 Na-ion batteries comprising honey comb boron carbon nitride (HBCN) nanomaterial as an anode.

IPC Classes  ?

• H01M 4/36 - Selection of substances as active materials, active masses, active liquids
• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers

Abstract

22 geo-sequestration projects.

IPC Classes  ?

• G01N 15/08 - Investigating permeability, pore volume, or surface area of porous materials
• G01N 7/04 - Analysing materials by measuring the pressure or volume of a gas or vapour by absorption, adsorption, or combustion of components and measurement of the change in pressure or volume of the remainder by absorption or adsorption alone

Abstract

Mismanagement of infectious wastes such as test samples leads to the transmission of microbes/toxins/viruses and spread of contagious and infectious diseases. Adding a flocculating agent to liquid waste reduces the risk of spills and aerosolization. Provide is a flocculating/gelating agent comprising the sol of a selected nanomaterial with a defined weight composition in water and a poly-amino acid (polyglutamic acid), that is capable of instantaneous flocculation/gelation, thereby disinfecting both liquid as well as solid samples, rendering them non-infectious, with >99.9% microbial disinfection. Segregation, transportation and incineration of such disinfected medical wastes are easier, safer and decrease medical waste disposal costs for a healthcare facility.

IPC Classes  ?

• A01N 25/04 - Dispersions or gels
• A01P 1/00 - DisinfectantsAntimicrobial compounds or mixtures thereof
• A61L 2/18 - Liquid substances
• A61L 11/00 - Disinfection or sterilising methods specially adapted for refuse
• A01N 37/46 - N-acyl derivatives
• A01N 59/16 - Heavy metalsCompounds thereof
• G01N 1/34 - PurifyingCleaning
• A01N 59/00 - Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
• A01N 59/06 - AluminiumCalciumMagnesiumCompounds thereof
• B09B 3/70 - Chemical treatment, e.g. pH adjustment or oxidation

Abstract

An air purification system with specific plants having microbes on rhizosphere/roots capable of removing pollutants from a surrounding environment. The system has a plurality of axial fans provided at an inlet and an outlet to facilitate flow of polluted air in and clean air out. The system has a perforated plate for collecting water in a water tank. The water tank with pump are for regular watering of the plants. The system has a pipe and nozzles for spraying of water with nutrients and a sensor for detecting pollutants. The system is capable of reducing a wide range of pollutants, such as particulate matter, volatile organic compounds (VOCs), sulfur oxides (SOx) and nitrogen oxides (NOx).

IPC Classes  ?

• F24F 8/175 - Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying by separation, e.g. by filtering using biological materials, plants or microorganisms
• B01D 53/85 - Biological processes with gas-solid contact
• A01G 31/02 - Special apparatus therefor

Abstract

2222 modified separator. Furthermore, the present invention provides energy device with said coated separator.

IPC Classes  ?

• C07C 319/00 - Preparation of thiols, sulfides, hydropolysulfides or polysulfides
• H01M 50/446 - Composite material consisting of a mixture of organic and inorganic materials

Abstract

The invented method is to realize a silicon chip carrier using wet bulk micromachining of silicon. In the silicon chip carrier, three (or more) supports are realized solely based on the wet etching of the silicon. The fabricated supports are triangular in shape and provide a minimum contact area between the sensing element and carrier. The invention provides a simple, cost-effective fabrication technology, which uses anisotropic wet etchant for silicon bulk-micromachining. A fabricated silicon wafer can be diced as per the requirement of single/multiple channel IR detectors. These chip carriers will cut down the IR detector cost with attractive lower thermal conductance in the field of gas sensors, spectrometry, thermal imaging, and fire detection.

IPC Classes  ?

• H01L 21/67 - Apparatus specially adapted for handling semiconductor or electric solid state devices during manufacture or treatment thereofApparatus specially adapted for handling wafers during manufacture or treatment of semiconductor or electric solid state devices or components

Abstract

The invention relates to a process for the synthesis of two-dimensionally-layered-structure represented by the general Formula I with improved properties having the advantages of photonic band gap material. The structure of Formula I show enhanced and spectrally controlled/tunable photo-luminescence. Particularly, an ink formulation is created from the annealed powder of the Formula I using a polymer as a binder and organic solvent as a dispersant. wherein, R1=R2=R3=alkyl or alkoxy hydrocarbon X=—CONH or —NH or —COO or —CO or —SO2NH n=1 or 2 or 3 The invention relates to a process for the synthesis of two-dimensionally-layered-structure represented by the general Formula I with improved properties having the advantages of photonic band gap material. The structure of Formula I show enhanced and spectrally controlled/tunable photo-luminescence. Particularly, an ink formulation is created from the annealed powder of the Formula I using a polymer as a binder and organic solvent as a dispersant. wherein, R1=R2=R3=alkyl or alkoxy hydrocarbon X=—CONH or —NH or —COO or —CO or —SO2NH n=1 or 2 or 3

IPC Classes  ?

• C09K 11/06 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials
• C09D 11/033 - Printing inks characterised by features other than the chemical nature of the binder characterised by the solvent
• C09D 11/108 - Hydrocarbon resins

Abstract

The present invention provides a transition metal-free electrocatalyst (AlOOH/NGr), comprising of monodispersed aluminium oxyhydroxide (A1OOH) sheets anchored over the electronically conducting nitrogen-doped graphene (NGr), for ORR (Oxygen reduction reaction). The AlOOH/NGr possesses good catalytic durability in alkaline medium. The invention further provides synthesis of AlOOH/NGr and its applications in an air electrode for fabricating a primary Zn-air battery.

IPC Classes  ?

• C25B 11/051 - Electrodes formed of electrocatalysts on a substrate or carrier
• H01M 4/96 - Carbon-based electrodes

Abstract

The present invention relates to a hybrid energy system and process of preparation thereof to generate hydrogen and electricity simultaneously, which is cost effective. The present invention provides an iron-doped hollow carbon nanorod (FeHCNR) by utilizing polydopamine (PDA), as a potential bifunctional catalyst for empowering both HER and 0 ORR. The present invention further provides method of preparation of FeHCNR and use thereof in hybrid battery system for simultaneous generation of electricity and hydrogen.

IPC Classes  ?

• C01B 3/00 - HydrogenGaseous mixtures containing hydrogenSeparation of hydrogen from mixtures containing itPurification of hydrogen

Abstract

The present invention discloses a continuous flow synthesis of mesoporous silica particles by using a reactor at shorter reaction times. The particle size of mesoporous silica particles are in the range of 400 nm-1.5 microns, and is monodispersed, surface area > 700 m2/g and pore size in the range of 2-4 nm.

IPC Classes  ?

• C01B 33/00 - SiliconCompounds thereof
• C01B 33/18 - Preparation of finely divided silica neither in sol nor in gel formAfter-treatment thereof

Abstract

The current invention describes Anion exchange polymer electrolyte membrane (AEPEM) by simple UV-irradiation procedure using simple acrylate/methacrylate monomers/oligomers, with at least one of them possessing quaternary ammonium group to obtain a polymer membrane, which when soaked in 6 M KOH solution yield an AEPEM having OH- group incorporated into the polymer matrix having good ionic conductivity.

IPC Classes  ?

• H01M 8/1018 - Polymeric electrolyte materials
• H01M 8/1067 - Polymeric electrolyte materials characterised by their physical properties, e.g. porosity, ionic conductivity or thickness

Abstract

A process for producing diazomethane of Formula 1 (CH2N2), with an automated apparatus is described. A stock solution of N-methyl-N-nitroso amine in an organic solvent is continuously flown and mixed with an aqueous inorganic base at a T-mixer to form a mixture. Then it is passed through a capillary micro reactor at a temperature in a range of 20 to 30° C. to form diazomethane. The mixture is separated into an aqueous layer and an organic layer using a continuous flow micro-separator. The organic layer has 0.1-0.4 M diazomethane. The organic layer is reacted with a carboxylic acid, phenol, an alkyne, an anhydride, a carboxyl metal organic framework (MOF), or MOF coated cotton to form a corresponding ester, a pyrazole, an ether, a diazo ketone, a stable carboxyl MOF or a stable MOF coated cotton fiber.

IPC Classes  ?

• C07C 245/16 - Diazomethane
• B01J 19/24 - Stationary reactors without moving elements inside
• B01J 19/00 - Chemical, physical or physico-chemical processes in generalTheir relevant apparatus

Abstract

The present invention overcomes the problem of processes yielding poor quantities of poly-gamma-glutamic-acid (γ-PGA) by providing a process and a novel medium for synthesis of γ-PGA in the presence of Bacillus paralicheniformis MCC 196. Wherein, the novel medium comprises tomato waste alone for cost effective and greener production of γ-PGA with yield of 40 g/L. In another process, non-sterile fermentation employs the use of a medium high in sugar content. Wherein, sucrose is used in concentrations up to 50% to obtain more than 280 g/L of poly gamma glutamic acid. The disclosed process is scalable and provides immense economic advantages.

IPC Classes  ?

• C12P 13/02 - Amides, e.g. chloramphenicol
• C12N 1/20 - BacteriaCulture media therefor

Abstract

The present invention is concerned with a novel convergent route for synthesis of BCX-1777 and BCX-4430. Two key starting materials that were carefully chosen for cross-coupling were a stable sugar intermediate, unlike the imine intermediates in the prior art, and dihalogenated pyrrolopyrimidine intermediate. A chemoselective cross-coupling was achieved from the two key starting materials, which upon reduction and activation resulted in stereoselective formation of an advanced intermediate in 55% yield from protected D-ribonolactone in 6 steps. The advanced intermediate then served as a starting material for synthesis of BCX-1777 and BCX-4430 in 38% (over 8 steps) and 32% (over 9 steps) yields, respectively from protected D-ribonolactone.

IPC Classes  ?

• A61P 1/00 - Drugs for disorders of the alimentary tract or the digestive system
• A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
• C07D 487/02 - Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups in which the condensed system contains two hetero rings

Abstract

A copolymer, poly(thiophene-co-benzothiophene-co-dibenzothiophene), and method of preparation thereof. The copolymer, poly(thiophene-co-benzothiophene-co-dibenzothiophene), having a formula (I): A copolymer, poly(thiophene-co-benzothiophene-co-dibenzothiophene), and method of preparation thereof. The copolymer, poly(thiophene-co-benzothiophene-co-dibenzothiophene), having a formula (I): A copolymer, poly(thiophene-co-benzothiophene-co-dibenzothiophene), and method of preparation thereof. The copolymer, poly(thiophene-co-benzothiophene-co-dibenzothiophene), having a formula (I): wherein x=H or R, y=H or R, z=H or R, and n=500-58000, wherein R is selected from alkyl or alicyclic chain substituents, and Ar is an aromatic ring.

IPC Classes  ?

• C08G 61/12 - Macromolecular compounds containing atoms other than carbon in the main chain of the macromolecule

Abstract

A fluid catalytic cracking process for p-cresol dimer to produce valuable phenolic monomers, i.e., 2-methyl phenol, 4-methyl phenol, 2,3-xylenol, and phenol, uses an equilibrium catalyst (E-cat) generated in the petroleum fluid catalytic cracking (FCC) unit. The p-cresol dimer can be processed under relatively mild conditions, while maximizing desired and minimizing undesired products. The process may include charging an equilibrium fluid catalytic cracking catalyst; heating to a predetermined cracking temperature and pressure; (c) charging a p-cresol dimer feed; (d) contacting the p-cresol dimer with the equilibrium fluid catalytic cracking catalyst; (e) condensing resulting phenolic monomer vapors to obtain phenolic monomer liquid and fluidization gas; (f) separating the phenolic monomer liquid from the fluidization gas; (g) collecting the separated phenolic monomer liquid; (h) separating the collected phenolic monomer liquid individual phenolic monomers; and (i) recycling any unconverted p-cresol dimer into the fluidized bed reactor.

IPC Classes  ?

• C07C 37/52 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions decreasing the number of carbon atoms by splitting polyaromatic compounds, e.g. polyphenolalkanes

Abstract

The present invention discloses a highly sensitive plasmonic substrate for the trace level detection of a wide variety of chemicals, biomolecules and a facile fabrication methodology thereof. The present invention plasmonic substrate produces enhanced Raman scattering of the adsorbed analyte materials of interest thereby enabling the trace level sensing through molecular fingerprinting. The developed methodology for the fabrication of SERS substrate involves nanostructuring of the selected materials through abrasive blasting and followed by coating with a nanolayer of coinage metals such as gold, silver, copper or the combinations thereof through thin film processes such as but not limited to thermal evaporation, electroless deposition.

IPC Classes  ?

• G01J 3/44 - Raman spectrometryScattering spectrometry
• G01N 21/65 - Raman scattering

Abstract

Ultrasonic pulse velocity (UPV) is an extremely important parameter for the assessment of strength of concrete structures and study of elastic properties. ASTM international standard: (ASTM: C597-09) covers the determination of the propagation velocity of longitudinal stress wave pulses through concrete. The suggested method involves transmission of longitudinal ultrasound by transmitting transducer and receiving by a suitable similar transducer. The transit time-measurement and the associated triggering pulses must provide the overall time-measurement resolution of at least 1 μs. The present invention relates to the design of ultrasonic pulse velocity measuring device capable to generate ultrasound preferably in the solid materials including concrete or material supporting the propagation of ultrasound and precisely measure the ultrasonic propagation delay time commonly known as the transit time. The present invention relates to an improved design of an ultrasonic transit time measurement device having provision for automatic pulse threshold error correction. The invention also discloses the method to realize fast counting for the generation of high resolution with relatively slower microcontrollers. The accuracy in the transit time measurement is relatively improved by subtracting the threshold corrected zero offset (without material under test) from the threshold corrected transit time (with sample).

IPC Classes  ?

• G01N 29/44 - Processing the detected response signal
• G01N 29/07 - Analysing solids by measuring propagation velocity or propagation time of acoustic waves
• G01N 29/34 - Generating the ultrasonic, sonic or infrasonic waves

Abstract

The present invention discloses a photocatalytic process and methodology for the preparation of acetic acid by a hydrocarboxylation reaction of methanol using carbon dioxide under visible light irradiation. Importantly, the reaction occurred under ambient temperature and pressure condition using a readily available household LED lamp in the presence of a transition metal based molecular photocatalyst, homogeneous as well as supported to semiconductor support and a CO2-philic solvent without adding any external electron and proton donors.

IPC Classes  ?

• C07C 51/15 - Preparation of carboxylic acids or their salts, halides, or anhydrides by reaction of organic compounds with carbon dioxide, e.g. Kolbe-Schmitt synthesis
• B01J 35/00 - Catalysts, in general, characterised by their form or physical properties
• B01J 31/16 - Catalysts comprising hydrides, coordination complexes or organic compounds containing coordination complexes

Abstract

The present invention discloses an improved process for the efficient solidification of biomedical waste that is capable of simultaneously treating and disinfecting solid and fluid samples. The process comprises of the addition of the waste samples to an alkaline aqueous solution followed by the addition of a solid material at a defined volumetric and/or weighted composition leading to instantaneous solidification with >99.9% microbial disinfection and an all-in-one disinfecting device 10 for treatment of biomedical waste.

IPC Classes  ?

• A61K 47/10 - AlcoholsPhenolsSalts thereof, e.g. glycerolPolyethylene glycols [PEG]PoloxamersPEG/POE alkyl ethers
• A61L 2/18 - Liquid substances
• B01D 21/01 - Separation of suspended solid particles from liquids by sedimentation using flocculating agents

Abstract

The present invention relates to design and applications of a class of water-soluble small molecules represented by formula 1. The said molecules, in their dilute aqueous solutions, exhibit lower critical solution temperature (LCST) phase transitions near room temperature, inducing a temperature triggered switching of opacity. Further, the present invention discloses a scalable smart window, akin to a radiative energy management system that can be incorporated into the built environment for imparting energy efficiency. The window fabrication is facile wherein the aqueous solution is sandwiched between two transparent glass panes to enable modulation of light and heat transmission. The dynamic window of present invention represents with multifarious applications in developing scalable, smart energy management systems for indoor building environments is envisioned to be a major contribution towards cost effective smart glass technologies.

IPC Classes  ?

• A61K 31/00 - Medicinal preparations containing organic active ingredients
• C09K 19/52 - Liquid crystal materials characterised by components which are not liquid crystals, e.g. additives
• C03C 17/06 - Surface treatment of glass, e.g. of devitrified glass, not in the form of fibres or filaments, by coating with metals

Abstract

paraparaparainter aliainter alia, methods for the preparation of compounds using heterogeneous recyclable catalyst. The methods of the present invention are useful for the preparation of a wide array of compounds. The compounds are synthesized rapidly, substantially free of side products and mostly does not require any purification. In particular, the methods of present invention are useful for preparing pharmaceutically active compounds or their intermediates.

IPC Classes  ?

• A61K 31/506 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
• C07D 209/16 - Tryptamines

Abstract

34233 with novel characterization features for the synthesis of CO, which is used as a reducing agent in the production of direct reduced metal from metal ore or mixture of metal oxides.

IPC Classes  ?

• C01B 3/12 - Production of hydrogen or of gaseous mixtures containing hydrogen by reaction of inorganic compounds containing electro-positively bound hydrogen, e.g. water, acids, bases, ammonia, with inorganic reducing agents by reaction of water vapour with carbon monoxide
• C01B 3/16 - Production of hydrogen or of gaseous mixtures containing hydrogen by reaction of inorganic compounds containing electro-positively bound hydrogen, e.g. water, acids, bases, ammonia, with inorganic reducing agents by reaction of water vapour with carbon monoxide using catalysts
• C10K 3/02 - Modifying the chemical composition of combustible gases containing carbon monoxide to produce an improved fuel, e.g. one of different calorific value, which may be free from carbon monoxide by catalytic treatment
• B01J 23/62 - Platinum group metals with gallium, indium, thallium, germanium, tin or lead
• B01J 23/75 - Cobalt

Abstract

An electrostatic coating system including of a novel technique of height adjustment through pressure sensing and feedback mechanism in twin-phase air-assisted and forced-liquid flow based electrostatic nozzle(s). A variable height electrostatic edible coating system provides uniform and efficient coating to ensure shelf-life extension, improved nutritional value and enhanced sensory attribute.

IPC Classes  ?

• B05B 12/00 - Arrangements for controlling deliveryArrangements for controlling the spray area
• A23B 7/16 - Coating with a protective layerCompositions or apparatus therefor
• B05B 5/10 - Arrangements for supplying power, e.g. charging power
• B05B 5/08 - Plant for applying liquids or other fluent materials to objects
• B05B 15/68 - Arrangements for adjusting the position of spray heads

Abstract

A method for desulfurizing crude oil and sulfur rich petroleum refinery fractions is disclosed. The method includes feeding the crude oil and sulfur rich petroleum refinery fractions to a reactor. An oxidation catalyst is added to the crude oil and sulfur rich petroleum refinery fractions. The crude oil and sulfur rich petroleum refinery fractions and the oxidation catalyst are stirred to form co-polymers of sulfur-containing heterocyclic compounds. The co-polymers of sulfur-containing heterocyclic compounds are separated by filtration or by centrifugation.

IPC Classes  ?

• C10G 49/04 - Treatment of hydrocarbon oils, in the presence of hydrogen or hydrogen-generating compounds, not provided for in a single one of groups , , , , or characterised by the catalyst used containing nickel, cobalt, chromium, molybdenum, or tungsten metals, or compounds thereof
• C10G 49/26 - Controlling or regulating

Abstract

Fluorescent bimetallic nanocomposites (M1@M2-NCs) of silver-gold (Ag@Au-NC) and silver-platinum (Ag@Pt-NC) are prepared by reducing silver nitrate (AgNO3) on gold nanoparticles (AuNPs) and platinum nanoparticles (PtNPs) using sodium borohydride (NaBH4) at alkaline pH=11, in the presence of a lysozyme that acts as a template, and in the presence of a capping and stabilizing agent. The biocompatible bimetallic nanocomposites (M1@M2-NCs) have promising multifunctional applications (cell imaging, bio-sensing, therapeutics) observed by both in vitro as well as in vivo experiments. The fluorescent bimetallic nanocomposites (M1@M2-NCs) of silver-gold (Ag@Au-NC) and silver-platinum (Ag@Pt-NC) may be useful as an alternative nanomedicine in cancer theranostics applications.

IPC Classes  ?

• A61K 47/64 - Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
• A61P 35/00 - Antineoplastic agents
• A61K 49/00 - Preparations for testing in vivo
• B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
• B22F 1/054 - Nanosized particles
• B22F 1/102 - Metallic powder coated with organic material
• B22F 1/17 - Metallic particles coated with metal
• B22F 9/24 - Making metallic powder or suspensions thereofApparatus or devices specially adapted therefor using chemical processes with reduction of metal compounds starting from liquid metal compounds, e.g. solutions

Abstract

The present invention relates to an assembly with a negatively charged dendrite inhibiting ionomer membrane made by cross-linking of sulfonated polyvinyl alcohol (PVS) and polyvinyl alcohol (PVA) for aqueous rechargeable zinc metal batteries (AZMBs).

IPC Classes  ?

• B01D 61/00 - Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltrationApparatus, accessories or auxiliary operations specially adapted therefor

Abstract

A highly active and exceptionally durable non-noble metal-sulphide based Hydrogen Evolution Reaction (HER) catalyst and the preparation thereof. More particularly, provided is a highly active earth abundant metal-sulphide based HER catalyst with exceptionally durable hydrogen evolution activity even after 100 hrs.

IPC Classes  ?

• C25B 11/091 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of at least one catalytic element and at least one catalytic compoundElectrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of two or more catalytic elements or catalytic compounds
• H01M 4/92 - Metals of platinum group
• C25B 1/04 - Hydrogen or oxygen by electrolysis of water

Abstract

The present invention relates to the design of a face mask that incorporates a waste derived warp knit polyethylene terephthalate (PET) permeate spacer layer for daily usage in current pandemic conditions. The central layer in the face masks is a selective hydrophobic layer that is recycled from waste RO membrane modules and is intended for usage as a non-medicated multi-layered face mask for common man. The mechanical strength and shape holding capability enables the preparation of the face mask in a unique 3D shape that extends from the nose bridge to the chin, leaving an air gap between the mouth and the inner layer of the face mask. Design advantage obtained by the incorporation of the PET layer enables smooth facial movements and hindrance free speaking. The 3D folding feature of the mask is seamless and fits snug on the user's face that which prevents spectacle fogging and chances of infections.

IPC Classes  ?

• A41D 13/11 - Protective face masks, e.g. for surgical use, or for use in foul atmospheres
• A62B 18/02 - Masks
• B01D 61/02 - Reverse osmosisHyperfiltration
• B01D 63/10 - Spiral-wound membrane modules
• A62B 23/06 - Nose filters
• A62B 7/10 - Respiratory apparatus with filter elements

Abstract

The present invention relates to design and applications of a class of water-soluble small molecules represented by Formula 1. In aqueous solutions the said molecules exhibit lower critical solution temperature (LCST) phase transition near room temperature, imparting a temperature triggered switching of transparency stages. Further, it discloses a solution comprising Formula 1 and a scalable smart radiative energy management system that takes form of a dynamic window, wherein the aqueous solution is sandwiched between two transparent glass panes to enable modulation of light and heat transmission. With simple and economical starting materials, the dynamic windows of present invention represent leaps towards creating a niche technology with multifarious applications in developing scalable, smart energy management systems for indoor building environments.

IPC Classes  ?

• C09K 9/02 - Organic tenebrescent materials

Abstract

The present invention discloses a solvent assisted cavitation process for the removal of pollutants from waste water comprising treating waste water in a batch or continuous process in a cavitation device fed with 1-10% of an immiscible solvent resulting in a reduction in concentration of ammoniacal nitrogen and/or COD in the waste water.

IPC Classes  ?

• C02F 1/34 - Treatment of water, waste water, or sewage with mechanical oscillations
• C02F 1/26 - Treatment of water, waste water, or sewage by extraction

Abstract

The present invention provides a process for the synthesis of Furandicarboxylic acid (FDCA) comprising heating a mixture of fructose, aqueous NaCl or KCl, solvent, methyl isobutyl ketone (MIBK) and a catalyst at a temperature in the range of 150 to 200° C. in a sealed vessel for a time period in the range of 2 to 5 hours to yield crude 5-(hydroxymethyl)furfural (5-HMF). The crude 5-HMF further reacts with a biocatalyst at a temperature in a range of 20 to 50° C. for a period at a range of 24 to 96 hours to yield FDCA, wherein the conversion of 5-HMF to FDCA is in the range of 90 to 100%.

IPC Classes  ?

• C07D 307/68 - Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Abstract

A continuous flow reactor without any moving parts to facilitate solid-liquid reaction without clogging is disclosed herein. It comprises plurality of identical cavities in series/sequence, each cavity being provided with: a pair of inlets at the top to allow entry of reactants into the reactor; an outlet at the bottom to allow the reactants to the next cavity for mixing; and a jacket covering around the cavities to provide heating or cooling effect as per the requirement. The outlet of the previous cavity is inclined at a suitable angle relative to the outlet of the next cavity to prevent clogging and facilitate efficient mixing of the reactants.

IPC Classes  ?

• B01J 19/24 - Stationary reactors without moving elements inside
• B01F 25/421 - Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path
• B01F 23/50 - Mixing liquids with solids
• B01F 35/92 - Heating or cooling systems for heating the outside of the receptacle, e.g. heated jackets or burners
• B01J 4/00 - Feed devicesFeed or outlet control devices

Abstract

The present invention relates to functionalized Maleimides and Isomaleimides of general Formula (I) and a process for the preparation thereof, involving [3+2] annulation of α, β-5 unsaturated aldehydes with carbamoyl alkylates via an enolate pathway to afford highly functionalized compounds of Formula (I);

IPC Classes  ?

• C07D 207/448 - Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having three double bonds between ring members or between ring members and non-ring members having two doubly-bound oxygen atoms directly attached in positions 2 and 5 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms, e.g. maleimide

Abstract

A continuous flow process for the synthesis of metal nanowires using a bubble column reactor. Also disclosed are different types of multiphase bubble column reactors for synthesizing metal nanowires in high yields and purity through a continuous process. The continuous process provides tunability for the aspect ratio of the nanowires.

IPC Classes  ?

• B22F 9/24 - Making metallic powder or suspensions thereofApparatus or devices specially adapted therefor using chemical processes with reduction of metal compounds starting from liquid metal compounds, e.g. solutions
• B01J 10/00 - Chemical processes in general for reacting liquid with gaseous media other than in the presence of solid particlesApparatus specially adapted therefor
• B01J 19/18 - Stationary reactors having moving elements inside
• B01J 4/00 - Feed devicesFeed or outlet control devices

Abstract

The present disclosure provides a continuous process for the synthesis coupled compounds of diazonium salts including azo dyes involving in-situ generation of diazonium salts. It further discloses a set up to carry out the process for the synthesis of coupled compounds of diazonium salts.

IPC Classes  ?

• C09B 67/00 - Influencing the physical, e.g. the dyeing or printing, properties of dyestuffs without chemical reaction, e.g. by treating with solventsProcess features in the making of dyestuff preparationsDyestuff preparations of a special physical nature, e.g. tablets, films
• C09B 67/54 - SeparationPurification
• C09B 41/00 - Special methods of performing the coupling reaction

Abstract

i2i322 in an extremely short time. The process is a combustion synthesis where a relatively low voltage in a range of 20-60 V/cm is applied using a DC/AC power source across the compact precursor material prior to ignition. The flash event is observed with a quick rise in current flow in a range of 100-300 mA/mm2 followed by measured temperature range of 1200-1400 °C in a green compact body of different MAX phase compositions. The process of the present invention enables the synthesis of MAX phases in air by suppressing oxidation of the material because of the very short residence time of the flashing event. In addition, the present invention focuses on synthesis of MAX phase in bulk to serve as the starting material for the development of two-dimensional MXenes.

IPC Classes  ?

• C04B 35/645 - Pressure sintering
• C04B 35/56 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on carbides

Abstract

A DVET unit (100) is disclosed that comprises a first syringe (104) and a second syringe (106) having a first plunger (154) and a second plunger (152), adapted to execute a backward stroke and a forward stroke in the respective syringe. The DVET unit (100) also includes a first valve (108) and a second valve (110). Further, the first valve (108) is closed and the second valve (110) is opened to draw blood from the source (142) and the specimen (102) into the first syringe (104) and the second syringe 106. Moreover, the first valve (108) is opened and the second valve (110) is closed to pump the blood, drawn during the backward stroke, from the first syringe (104) and the second syringe (106) into the specimen (102) and the waste bin 144.

IPC Classes  ?

• A61M 1/02 - Blood transfusion apparatus
• A61M 5/14 - Infusion devices, e.g. infusing by gravityBlood infusionAccessories therefor

Abstract

This invention provides a process for the preparation of orthogonally protected ribose derivative. Which are further used as donor for the synthesis of N4-hydroxy cytidine and its derivatives by using commercially available materials under very mild reaction condition and short period of time. Thereafter N-hydroxylation of cytidine can be achieved in a short period of time. The intermediates or the final compounds thus obtained can be used for the treatment of viral infections.

IPC Classes  ?

• C07H 19/067 - Pyrimidine radicals with ribosyl as the saccharide radical

Abstract

This invention provides a process for the preparation of orthogonally protected ribose derivative. Which are further used as donor for the synthesis of N4-hydroxy cytidine and its derivatives by using commercially available materials under very mild reaction condition and short period of time. Thereafter N-hydroxylation of cytidine can be achieved in a short period of time. The intermediates or the final compounds thus obtained can be used for the treatment of viral infections.

IPC Classes  ?

• C07H 19/067 - Pyrimidine radicals with ribosyl as the saccharide radical
• C07H 19/06 - Pyrimidine radicals

Abstract

Present invention relates to a short and cost-effective synthetic process for synthesis of a broad-spectrum antiviral drug Molnupiravir (EIDD 2801) of formula I. Particularly, the present invention relates to a process for synthesis of a broad-spectrum antiviral drug EIDD 2801 via a short synthetic route from the basic starting material D-ribose. The present invention also decreases the usage of purification processes such as column chromatography after individual steps in comparison to the prior arts which makes the present process a green alternative. Finally, the use of cheap raw materials makes the process cost effective and industrially viable.

IPC Classes  ?

• A61K 31/7004 - Monosaccharides having only carbon, hydrogen and oxygen atoms

Abstract

The present invention relates to an enzymatic process for preparation of optically pure enantiomers of homopropargylic alcohol compounds of formula I, which are useful intermediates for the synthesis of Halichondrin B and analogs. wherein, P is H or an alcohol protecting group, n is an integer ranging from 0-12. The present invention relates to an enzymatic process for preparation of optically pure enantiomers of homopropargylic alcohol compounds of formula I, which are useful intermediates for the synthesis of Halichondrin B and analogs. wherein, P is H or an alcohol protecting group, n is an integer ranging from 0-12.

IPC Classes  ?

• C12P 7/04 - Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
• C12P 7/625 - Polyesters of hydroxy carboxylic acids
• C12P 41/00 - Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
• C12N 9/20 - Triglyceride splitting, e.g. by means of lipase

Abstract

A geo-polymeric concrete and a process for preparing the geo-polymeric concrete is disclosed. The geo-polymeric concrete includes class F fly ash in a range from 10-20 wt %, of the design mix river sand in a range from 25-40 wt % of the design mix, a natural aggregate in a range from 15 to 40 wt % of the design mix, silica fume in a range from 1 to 2 wt % of class F fly ash, an alkaline activator solution and a superplasticizer in a range from 0.5 to 3 wt %. The materials used for preparing the superplasticizer are easily available in the market in abundance at a reasonable cost. The superplasticizer is economically viable and improves the workability of the geo-polymeric concrete. The presence of the superplasticizer does not affect the compressive strength of the geo-polymeric concrete.

IPC Classes  ?

• C04B 28/00 - Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements
• C04B 14/06 - QuartzSand
• C04B 18/14 - Waste materialsRefuse from metallurgical processes
• C04B 18/08 - Flue dust
• C04B 18/02 - Agglomerated materials
• C04B 24/10 - Carbohydrates or derivatives thereof
• C04B 24/02 - AlcoholsPhenolsEthers
• C04B 22/06 - OxidesHydroxides