Goods & Services

Silicon nitride based wound care products; silicon nitride based antimicrobial preparations for medical use Silicon nitride based orthopedic implants for internal bone fixation in spine, ankle and foot

Goods & Services

osteotomy wedges for internal bone fixation in the ankle and foot

Abstract

Methods for improving the antibacterial and/or bone-forming characteristics of biomedical implants and related implants manufactured according to such methods. In some implementations, a biomedical implant may comprise a composite of a silicon nitride ceramic powder dispersed within a poly-ether-ether-ketone (PEEK) or a poly-ether-ketone-ketone (PEKK) substrate material. In some implementations, the biomedical implant may be 3D printed.

IPC Classes  ?

• A61L 31/02 - Inorganic materials
• A61L 27/06 - Titanium or titanium alloys
• A61L 27/30 - Inorganic materials
• A61L 27/50 - Materials characterised by their function or physical properties
• A61L 31/08 - Materials for coatings
• A61L 31/12 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material
• A61L 31/14 - Materials characterised by their function or physical properties
• A61L 31/16 - Biologically active materials, e.g. therapeutic substances

Abstract

Described herein is an antiviral face mask and methods of use thereof to inactivate a virus in contact with the face mask. The face mask may include a fibrous material with silicon nitride powder impregnated therein and a layer surrounding the fibrous material. In some embodiments, silicon nitride is present in the fibrous material at a concentration of about 1 wt. % to about 15 wt. %.

IPC Classes  ?

• A41D 13/11 - Protective face masks, e.g. for surgical use, or for use in foul atmospheres
• D06B 13/00 - Treatment of textile materials with liquids, gases, or vapours with aid of vibration
• D06M 11/77 - Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereofSuch treatment combined with mechanical treatment, e.g. mercerising with silicon or compounds thereof

Abstract

Disclosed herein are antifungal composites, devices, and methods to reduce or prevent a fungus from growing on the antifungal composite. The antifungal composite and devices thereof may include a biocompatible polymer and a Si3N4 powder loaded in at least a portion of the biocompatible polymer. The polymer may be a thermoplastic polymer such as a poly(methyl methacrylate) (PMMA) resin and the Si3N4 powder may be present in a concentration of about 1 vol. % to about 30 vol. % in the thermoplastic polymer.

IPC Classes  ?

• A01N 59/00 - Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
• A01N 25/10 - Macromolecular compounds
• A01N 25/12 - Powders or granules
• A61K 6/76 - Fillers comprising silicon-containing compounds
• A61C 13/087 - Artificial resin teeth
• A61K 6/889 - Polycarboxylate cementsGlass ionomer cements

Abstract

Disclosed herein are compositions, devices and methods for inactivating viruses, bacteria, and fungi. The compositions, methods, and devices may include coatings or slurries such as silicon nitride powder coatings or slurries for the inactivation of viruses, bacteria, and/or fungi.

IPC Classes  ?

• C01B 21/068 - Binary compounds of nitrogen with metals, with silicon, or with boron with silicon
• A01C 1/06 - Coating or dressing seed
• A01N 25/32 - Ingredients for reducing the noxious effect of the active substances to organisms other than pests, e.g. toxicity reducing compositions, self-destructing compositions
• A01N 59/02 - SulfurSeleniumTelluriumCompounds thereof

Abstract

The present disclosure relates to the manufacture of silicon nitride implants with increased surface roughness and porosity. Disclosed herein are methods for manufacturing silicon nitride implants having enhanced osseointegrative effectiveness. The disclosed method includes providing a silicon nitride green body, increasing the surface roughness of the silicon nitride green body, increasing the porosity of the silicon nitride green body, and then sintering the silicon nitride green body to obtain a silicon nitride implant.The step of increasing the surface roughness of the silicon nitride green body may be performed by laser etching. The step of increasing the porosity of the silicon nitride green body may be performed by peck drilling and/or laser etching.

IPC Classes  ?

• A61F 2/44 - Joints for the spine, e.g. vertebrae, spinal discs
• B23K 26/34 - Laser welding for purposes other than joining
• C04B 35/597 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on borides, nitrides or silicides based on silicon oxynitrides
• A61L 27/30 - Inorganic materials
• A61L 27/54 - Biologically active materials, e.g. therapeutic substances
• B23K 26/0622 - Shaping the laser beam, e.g. by masks or multi-focusing by direct control of the laser beam by shaping pulses
• C04B 41/53 - After-treatment of mortars, concrete, artificial stone or ceramicsTreatment of natural stone involving the removal of part of the materials of the treated article

Abstract

The present disclosure relates to the manufacture of silicon nitride implants with increased surface roughness and porosity.

IPC Classes  ?

• C04B 35/584 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on borides, nitrides or silicides based on silicon nitride
• A61L 27/10 - Ceramics or glasses

Abstract

Disclosed herein are systems and methods for physical vapor deposition silicon nitride coatings. The methods thereof may include a creating a magnetically confined plasma near a surface of a silicon nitride. The plasma may cause positively charged energetic ions from the plasma to collide with negatively charged silicon nitride atoms, causing the silicon nitride atoms to be sputtered and deposited on a substrate such as titanium. The silicon nitride coating may be nitrogen-rich silicon nitride or silicon-rich silicon nitride.

IPC Classes  ?

• C23C 14/06 - Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material characterised by the coating material
• C23C 14/35 - Sputtering by application of a magnetic field, e.g. magnetron sputtering

Abstract

Disclosed herein are systems and methods for physical vapor deposition silicon nitride coatings. The methods thereof may include a creating a magnetically confined plasma near a surface of a silicon nitride. The plasma may cause positively charged energetic ions from the plasma to collide with negatively charged silicon nitride atoms, causing the silicon nitride atoms to be sputtered and deposited on a substrate such as titanium. The silicon nitride coating may be nitrogen-rich silicon nitride or silicon-rich silicon nitride.

IPC Classes  ?

• C23C 14/06 - Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material characterised by the coating material
• C23C 14/35 - Sputtering by application of a magnetic field, e.g. magnetron sputtering

Abstract

Disclosed herein are systems and methods for physical vapor deposition silicon nitride coatings. The methods thereof may include a creating a magnetically confined plasma near a surface of a silicon nitride. The plasma may cause positively charged energetic ions from the plasma to collide with negatively charged silicon nitride atoms, causing the silicon nitride atoms to be sputtered and deposited on a substrate such as titanium. The silicon nitride coating may be nitrogen-rich silicon nitride or silicon-rich silicon nitride.

IPC Classes  ?

• A01N 59/00 - Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
• H01J 37/34 - Gas-filled discharge tubes operating with cathodic sputtering
• C23C 14/35 - Sputtering by application of a magnetic field, e.g. magnetron sputtering
• C23C 14/06 - Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material characterised by the coating material

Abstract

Described herein is an antiviral face mask and methods of use thereof to inactivate a virus in contact with the face mask. The face mask may include a fibrous material with silicon nitride powder impregnated therein and a layer surrounding the fibrous material. In some embodiments, silicon nitride is present in the fibrous material at a concentration of about 30 wt. % to about 50 wt. %.

IPC Classes  ?

• A41D 13/11 - Protective face masks, e.g. for surgical use, or for use in foul atmospheres
• A61M 16/06 - Respiratory or anaesthetic masks
• B32B 5/02 - Layered products characterised by the non-homogeneity or physical structure of a layer characterised by structural features of a layer comprising fibres or filaments
• B32B 33/00 - Layered products characterised by particular properties or particular surface features, e.g. particular surface coatingsLayered products designed for particular purposes not covered by another single class
• B32B 17/10 - Layered products essentially comprising sheet glass, or fibres of glass, slag or the like comprising glass as the main or only constituent of a layer, next to another layer of a specific substance of synthetic resin

Abstract

Methods for improving the wear performance of silicon nitride and/or other ceramic materials, particularly to make them more suitable for use in manufacturing biomedical implants.

IPC Classes  ?

• A61F 2/30 - Joints
• A61F 2/34 - Acetabular cups
• A61L 27/10 - Ceramics or glasses
• A61F 2/36 - Femoral heads
• A61L 31/02 - Inorganic materials

Abstract

Disclosed herein are methods for functionalizing the surface of a biomedical implant. The biomedical implant may be a zirconia-toughened alumina implant surface functionalized with silicon nitride powder for promoting osteogenesis.

IPC Classes  ?

• C04B 41/00 - After-treatment of mortars, concrete, artificial stone or ceramicsTreatment of natural stone
• A61F 2/30 - Joints
• B23K 26/00 - Working by laser beam, e.g. welding, cutting or boring
• B23K 26/0622 - Shaping the laser beam, e.g. by masks or multi-focusing by direct control of the laser beam by shaping pulses
• B23K 26/342 - Build-up welding
• C04B 35/10 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxides based on aluminium oxide
• C04B 41/45 - Coating or impregnating
• C04B 41/50 - Coating or impregnating with inorganic materials
• C04B 41/53 - After-treatment of mortars, concrete, artificial stone or ceramicsTreatment of natural stone involving the removal of part of the materials of the treated article
• C04B 41/87 - Ceramics
• C04B 41/91 - After-treatment of mortars, concrete, artificial stone or ceramicsTreatment of natural stone of only ceramics involving the removal of part of the materials of the treated articles, e.g. etching
• B23K 103/00 - Materials to be soldered, welded or cut

Abstract

Described herein are antiviral compositions and apparatuses and methods of use thereof to inactivate a virus in contact with the composition or apparatus. The composition and/or apparatus include silicon nitride at a concentration of 1 wt.% to 15 wt.% and the silicon nitride inactivates at least 85% of the virus in contact with the composition and/or apparatus.

IPC Classes  ?

• A61K 33/00 - Medicinal preparations containing inorganic active ingredients
• A61K 33/08 - OxidesHydroxides
• A61P 31/12 - Antivirals
• A61P 31/14 - Antivirals for RNA viruses
• A61P 31/16 - Antivirals for RNA viruses for influenza or rhinoviruses

Abstract

Described herein are antiviral compositions and apparatuses and methods of use thereof to inactivate a virus in contact with the composition or apparatus. The composition and/or apparatus include silicon nitride at a concentration of 1 wt.% to 15 wt.% and the silicon nitride inactivates at least 85% of the virus in contact with the composition and/or apparatus.

IPC Classes  ?

• A61K 31/52 - Purines, e.g. adenine
• A61K 31/70 - CarbohydratesSugarsDerivatives thereof
• A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
• A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
• A61P 25/00 - Drugs for disorders of the nervous system

Abstract

Described herein are antipathogenic compositions comprising a nitride chosen from aluminum nitride, boron nitride, chromium nitride, cerium nitride, hafnium nitride, lanthanum nitride, phosphorous nitride, sulfur nitride, tantalum nitride, titanium nitride, vanadium nitride, yttrium nitride, zirconium nitride, silicon nitride, or combinations thereof, and methods of using said compositions to inactivate viruses, bacteria, and/or fungi.

IPC Classes  ?

• A01N 25/08 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
• A01N 59/00 - Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
• A61L 2/23 - Solid substances, e.g. granules, powders, blocks, tablets

Abstract

Described herein are antipathogenic compositions comprising a nitride chosen from aluminum nitride, boron nitride, chromium nitride, cerium nitride, hafnium nitride, lanthanum nitride, phosphorous nitride, sulfur nitride, tantalum nitride, titanium nitride, vanadium nitride, yttrium nitride, zirconium nitride, silicon nitride, or combinations thereof, and methods of using said compositions to inactivate viruses, bacteria, and/or fungi.

IPC Classes  ?

• A01N 25/08 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests containing solids as carriers or diluents
• A01N 59/00 - Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
• A61L 2/23 - Solid substances, e.g. granules, powders, blocks, tablets

Abstract

Methods and systems for manufacturing a component are disclosed. The method for manufacturing a component typically comprises blending a silicon nitride powder and a titanium alloy powder to form a combined powder; receiving the combined powder within a build chamber having a platform and a laser beam source configured to produce a laser beam; spreading a plurality of layers of the combined powder over the platform; fusing at least a portion of the combined powder in each of the plurality of layers using the laser beam, wherein each one of the plurality of layers is spread and the portion of the combined powder fused before another one of the plurality of layers is spread, wherein the laser beam is automatically guided by a 3D model of the component; and removing the combined powder that was not fused.

IPC Classes  ?

• B22F 10/28 - Powder bed fusion, e.g. selective laser melting [SLM] or electron beam melting [EBM]
• B22F 12/41 - Radiation means characterised by the type, e.g. laser or electron beam
• B22F 10/66 - Treatment of workpieces or articles after build-up by mechanical means
• B22F 10/62 - Treatment of workpieces or articles after build-up by chemical means
• B22F 12/58 - Means for feeding of material, e.g. heads for changing the material composition, e.g. by mixing
• B22F 1/00 - Metallic powderTreatment of metallic powder, e.g. to facilitate working or to improve properties
• B22F 10/68 - Cleaning or washing
• B33Y 10/00 - Processes of additive manufacturing
• B33Y 40/10 - Pre-treatment
• B33Y 40/20 - Post-treatment, e.g. curing, coating or polishing
• B33Y 70/00 - Materials specially adapted for additive manufacturing
• B33Y 80/00 - Products made by additive manufacturing

Abstract

Methods and systems for manufacturing a component are disclosed. The method for manufacturing a component typically comprises blending a silicon nitride powder and a titanium alloy powder to form a combined powder; receiving the combined powder within a build chamber having a platform and a laser beam source configured to produce a laser beam; spreading a plurality of layers of the combined powder over the platform; fusing at least a portion of the combined powder in each of the plurality of layers using the laser beam, wherein each one of the plurality of layers is spread and the portion of the combined powder fused before another one of the plurality of layers is spread, wherein the laser beam is automatically guided by a 3D model of the component; and removing the combined powder that was not fused.

IPC Classes  ?

• B23K 26/00 - Working by laser beam, e.g. welding, cutting or boring
• B23K 26/342 - Build-up welding
• B28B 1/00 - Producing shaped articles from the material

Abstract

Methods and systems for manufacturing a ceramic or glass material component supersaturated in nitrogen are disclosed. The method for manufacturing a component typically comprises receiving the ceramic or glass material within a containment vessel; simultaneously heating and applying isostatic pressure to the ceramic or glass material within the containment vessel to a first temperature and a first pressure using pressurizing nitrogen gas; holding the first temperature and the first pressure for a period of time; cooling the ceramic or glass material within the containment vessel to a second temperature while maintaining the first pressure; and depressurizing the containment vessel to a second pressure.

IPC Classes  ?

• C04B 35/515 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides
• C04B 35/58 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on borides, nitrides or silicides
• C04B 35/584 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on borides, nitrides or silicides based on silicon nitride
• C04B 35/593 - Fine ceramics obtained by pressure sintering

Abstract

Methods and systems for manufacturing a component are disclosed. The method for manufacturing a component typically comprises blending a silicon nitride powder and a titanium alloy powder to form a combined powder; receiving the combined powder within a build chamber having a platform and a laser beam source configured to produce a laser beam; spreading a plurality of layers of the combined powder over the platform; fusing at least a portion of the combined powder in each of the plurality of layers using the laser beam, wherein each one of the plurality of layers is spread and the portion of the combined powder fused before another one of the plurality of layers is spread, wherein the laser beam is automatically guided by a 3D model of the component; and removing the combined powder that was not fused.

IPC Classes  ?

• B23K 26/00 - Working by laser beam, e.g. welding, cutting or boring
• B23K 26/342 - Build-up welding
• B28B 1/00 - Producing shaped articles from the material

Abstract

Methods and systems for manufacturing a ceramic or glass material component supersaturated in nitrogen are disclosed. The method for manufacturing a component typically comprises receiving the ceramic or glass material within a containment vessel; simultaneously heating and applying isostatic pressure to the ceramic or glass material within the containment vessel to a first temperature and a first pressure using pressurizing nitrogen gas; holding the first temperature and the first pressure for a period of time; cooling the ceramic or glass material within the containment vessel to a second temperature while maintaining the first pressure; and depressurizing the containment vessel to a second pressure.

IPC Classes  ?

• A61L 27/10 - Ceramics or glasses
• C04B 35/593 - Fine ceramics obtained by pressure sintering
• C04B 35/645 - Pressure sintering
• A61L 27/54 - Biologically active materials, e.g. therapeutic substances

Abstract

Methods and systems for manufacturing a ceramic or glass material component supersaturated in nitrogen are disclosed. The method for manufacturing a component typically comprises receiving the ceramic or glass material within a containment vessel; simultaneously heating and applying isostatic pressure to the ceramic or glass material within the containment vessel to a first temperature and a first pressure using pressurizing nitrogen gas; holding the first temperature and the first pressure for a period of time; cooling the ceramic or glass material within the containment vessel to a second temperature while maintaining the first pressure; and depressurizing the containment vessel to a second pressure.

IPC Classes  ?

• C04B 35/584 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on borides, nitrides or silicides based on silicon nitride
• C04B 35/58 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on borides, nitrides or silicides
• C04B 35/515 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides
• C04B 35/593 - Fine ceramics obtained by pressure sintering

Abstract

Described herein are antipathogenic compositions comprising a nitride chosen from aluminum nitride, boron nitride, chromium nitride, cerium nitride, hafnium nitride, lanthanum nitride, phosphorous nitride, sulfur nitride, tantalum nitride, titanium nitride, vanadium nitride, yttrium nitride, zirconium nitride, silicon nitride, or combinations thereof, and methods of using said compositions to inactivate viruses, bacteria, and/or fungi.

IPC Classes  ?

• A01N 59/00 - Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
• A01N 59/06 - AluminiumCalciumMagnesiumCompounds thereof
• A01N 59/14 - BoronCompounds thereof
• A61K 33/06 - Aluminium, calcium or magnesiumCompounds thereof
• A61K 33/22 - Boron compounds
• A61K 33/00 - Medicinal preparations containing inorganic active ingredients

Abstract

Disclosed herein are compositions, devices and methods for inactivating viruses, bacteria, and fungi. The compositions, methods, and devices may include coatings or slurries such as silicon nitride powder coatings or slurries for the inactivation of viruses, bacteria, and/or fungi.

IPC Classes  ?

• C01B 21/068 - Binary compounds of nitrogen with metals, with silicon, or with boron with silicon
• A01C 1/06 - Coating or dressing seed
• A01N 59/02 - SulfurSeleniumTelluriumCompounds thereof
• A01N 25/32 - Ingredients for reducing the noxious effect of the active substances to organisms other than pests, e.g. toxicity reducing compositions, self-destructing compositions

Abstract

Methods for improving the antibacterial and/or bone-forming characteristics of biomedical implants and related implants manufactured according to such methods. In some implementations, a biomedical implant may comprise a composite of a silicon nitride ceramic powder dispersed within a poly-ether-ether-ketone (PEEK) or a poly-ether-ketone-ketone (PEKK) substrate material. In some implementations, the biomedical implant may be 3D printed.

IPC Classes  ?

• A61L 31/02 - Inorganic materials
• A61L 31/16 - Biologically active materials, e.g. therapeutic substances
• A61L 31/12 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material
• A61L 31/08 - Materials for coatings
• A61L 27/30 - Inorganic materials
• A61L 31/14 - Materials characterised by their function or physical properties
• A61L 27/50 - Materials characterised by their function or physical properties
• A61L 27/06 - Titanium or titanium alloys

Abstract

Various embodiments related to systems, methods, and articles for rapid inactivation of SARS-CoV-2 by silicon nitride and aluminum nitride are disclosed herein.

IPC Classes  ?

• A01N 25/00 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests
• A01N 25/34 - Shaped forms, e.g. sheets, not provided for in any other group of this main group
• A01N 59/00 - Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
• A01N 59/06 - AluminiumCalciumMagnesiumCompounds thereof
• A01P 1/00 - DisinfectantsAntimicrobial compounds or mixtures thereof
• A41D 13/00 - Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches
• A41D 31/00 - Materials specially adapted for outerwear
• A61L 2/16 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor using chemical substances

Abstract

Various embodiments related to systems, methods, and articles for rapid inactivation of SARS-CoV-2 by silicon nitride and aluminum nitride are disclosed herein.

IPC Classes  ?

• A01N 25/04 - Dispersions or gels
• A01N 25/34 - Shaped forms, e.g. sheets, not provided for in any other group of this main group
• A01N 59/06 - AluminiumCalciumMagnesiumCompounds thereof
• A41D 13/00 - Professional, industrial or sporting protective garments, e.g. surgeons' gowns or garments protecting against blows or punches

Abstract

Various embodiments for antipathogenic devices and methods thereof for antifungal applications are disclosed herein.

IPC Classes  ?

• A01C 1/06 - Coating or dressing seed
• A01N 25/32 - Ingredients for reducing the noxious effect of the active substances to organisms other than pests, e.g. toxicity reducing compositions, self-destructing compositions
• A01N 59/02 - SulfurSeleniumTelluriumCompounds thereof
• C01B 21/068 - Binary compounds of nitrogen with metals, with silicon, or with boron with silicon

Abstract

Various embodiments for antipathogenic devices and methods thereof for antifungal applications are disclosed herein.

IPC Classes  ?

• A01C 1/06 - Coating or dressing seed
• A01N 25/32 - Ingredients for reducing the noxious effect of the active substances to organisms other than pests, e.g. toxicity reducing compositions, self-destructing compositions
• A01N 59/02 - SulfurSeleniumTelluriumCompounds thereof
• C01B 21/068 - Binary compounds of nitrogen with metals, with silicon, or with boron with silicon

Abstract

Disclosed herein are methods for laser cladding a coating the surface of a biomedical implant. The biomedical implant may be an implant with a laser-cladded silicon nitride coating for promoting osteogenesis.

IPC Classes  ?

• A61L 27/28 - Materials for coating prostheses
• A61L 27/30 - Inorganic materials
• A61L 27/50 - Materials characterised by their function or physical properties

Abstract

Disclosed herein are methods for laser cladding a coating the surface of a biomedical implant. The biomedical implant may be an implant with a laser-cladded silicon nitride coating for promoting osteogenesis.

IPC Classes  ?

• C23C 24/00 - Coating starting from inorganic powder
• A61L 27/30 - Inorganic materials
• A61L 27/54 - Biologically active materials, e.g. therapeutic substances
• B23K 26/0622 - Shaping the laser beam, e.g. by masks or multi-focusing by direct control of the laser beam by shaping pulses
• B23K 26/12 - Working by laser beam, e.g. welding, cutting or boring in a special environment or atmosphere, e.g. in an enclosure
• B23K 26/324 - Bonding taking account of the properties of the material involved involving non-metallic parts
• B23K 26/60 - Preliminary treatment
• C22C 14/00 - Alloys based on titanium
• C23C 26/00 - Coating not provided for in groups

Abstract

Various embodiment related to methods for coating a metal substrate with a silicon nitride ceramic coating are disclosed herein. The metal substrate may be a biomedical implant with a laser-cladded silicon nitride coating for promoting osteogenesis.

IPC Classes  ?

• B23K 26/342 - Build-up welding
• B23K 26/12 - Working by laser beam, e.g. welding, cutting or boring in a special environment or atmosphere, e.g. in an enclosure
• C23C 24/10 - Coating starting from inorganic powder by application of heat or pressure and heat with intermediate formation of a liquid phase in the layer

Abstract

Disclosed herein are methods for laser cladding a coating the surface of a biomedical implant. The biomedical implant may be an implant with a laser-cladded silicon nitride coating for promoting osteogenesis.

IPC Classes  ?

• A61L 27/30 - Inorganic materials
• A61L 27/50 - Materials characterised by their function or physical properties
• A61L 27/00 - Materials for prostheses or for coating prostheses
• A61L 27/28 - Materials for coating prostheses
• A61F 2/28 - Bones
• A61F 2/30 - Joints

Abstract

Various embodiment related to methods for coating a metal substrate with a silicon nitride ceramic coating are disclosed herein. The metal substrate may be a biomedical implant with a laser-cladded silicon nitride coating for promoting osteogenesis.

IPC Classes  ?

• A61L 27/02 - Inorganic materials
• A61L 27/54 - Biologically active materials, e.g. therapeutic substances

Abstract

Various embodiment related to methods for coating a metal substrate with a silicon nitride ceramic coating are disclosed herein. The metal substrate may be a biomedical implant with a laser-cladded silicon nitride coating for promoting osteogenesis.

IPC Classes  ?

• A61L 27/02 - Inorganic materials
• A61L 27/54 - Biologically active materials, e.g. therapeutic substances
• C04B 35/597 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on borides, nitrides or silicides based on silicon oxynitrides

Abstract

Described herein is an antiviral face mask and methods of use thereof to inactivate a virus in contact with the face mask. The face mask may include a fibrous material with silicon nitride powder impregnated therein and a layer surrounding the fibrous material. In some embodiments, silicon nitride is present in the fibrous material at a concentration of about 1 wt.% to about 15 wt.%.

IPC Classes  ?

• A41D 13/11 - Protective face masks, e.g. for surgical use, or for use in foul atmospheres
• C01B 21/068 - Binary compounds of nitrogen with metals, with silicon, or with boron with silicon

Abstract

Various embodiments for antipathogenic devices and methods thereof for antifungal applications are disclosed herein.

IPC Classes  ?

• A01N 59/00 - Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds

Abstract

Described herein is an antiviral face mask and methods of use thereof to inactivate a virus in contact with the face mask. The face mask may include a fibrous material with silicon nitride powder impregnated therein and a layer surrounding the fibrous material. In some embodiments, silicon nitride is present in the fibrous material at a concentration of about 1 wt.% to about 15 wt.%.

IPC Classes  ?

• A41D 13/11 - Protective face masks, e.g. for surgical use, or for use in foul atmospheres
• A01N 25/12 - Powders or granules
• A01N 59/00 - Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
• A01P 1/00 - DisinfectantsAntimicrobial compounds or mixtures thereof
• C01B 21/068 - Binary compounds of nitrogen with metals, with silicon, or with boron with silicon

Abstract

Described herein is an antiviral face mask and methods of use thereof to inactivate a virus in contact with the face mask. The face mask may include a fibrous material with silicon nitride powder impregnated therein and a layer surrounding the fibrous material. In some embodiments, silicon nitride is present in the fibrous material at a concentration of about 1 wt. % to about 15 wt. %.

IPC Classes  ?

• D06B 13/00 - Treatment of textile materials with liquids, gases, or vapours with aid of vibration
• D06M 13/00 - Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials with non-macromolecular organic compoundsSuch treatment combined with mechanical treatment
• A41D 13/11 - Protective face masks, e.g. for surgical use, or for use in foul atmospheres
• D06M 11/77 - Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials, with inorganic substances or complexes thereofSuch treatment combined with mechanical treatment, e.g. mercerising with silicon or compounds thereof
• D06M 101/20 - Polyalkenes, polymers or copolymers of compounds with alkenyl groups bonded to aromatic groups

Abstract

Various embodiments related to systems, methods, and articles for rapid inactivation of SARS-CoV-2 by silicon nitride and aluminum nitride are disclosed herein.

IPC Classes  ?

• A01N 59/06 - AluminiumCalciumMagnesiumCompounds thereof
• A01N 59/00 - Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
• A61L 31/16 - Biologically active materials, e.g. therapeutic substances
• A61L 31/08 - Materials for coatings
• D06N 3/12 - Artificial leather, oilcloth, or like material obtained by covering fibrous webs with macromolecular material, e.g. resins, rubber or derivatives thereof with macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds

Abstract

Described herein are antiviral compositions and apparatuses and methods of use thereof to inactivate a virus in contact with the composition or apparatus. The composition and/or apparatus include silicon nitride at a concentration of 1 wt. % to 15 wt. % and the silicon nitride inactivates at least 85% of the virus in contact with the composition and/or apparatus.

IPC Classes  ?

• A61K 33/00 - Medicinal preparations containing inorganic active ingredients
• A61K 8/25 - SiliconCompounds thereof
• A61Q 11/00 - Preparations for care of the teeth, of the oral cavity or of dentures, e.g. dentifrices or toothpastesMouth rinses
• A61P 31/16 - Antivirals for RNA viruses for influenza or rhinoviruses
• A61L 2/23 - Solid substances, e.g. granules, powders, blocks, tablets

Abstract

4 powder may be present in a concentration of about 1 vol. % to about 30 vol. % in the thermoplastic polymer.

IPC Classes  ?

• A01N 59/00 - Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
• A61K 6/76 - Fillers comprising silicon-containing compounds
• A01N 25/10 - Macromolecular compounds
• A01N 25/12 - Powders or granules
• A61C 13/087 - Artificial resin teeth
• A61K 6/889 - Polycarboxylate cementsGlass ionomer cements

Abstract

Disclosed herein are antifungal composites, devices, and methods to reduce or prevent a fungus from growing on the antifungal composite. The antifungal composite and devices thereof may include a biocompatible polymer and a Si3N4 powder loaded in at least a portion of the biocompatible polymer. The polymer may be a thermoplastic polymer such as a poly(methyl methacrylate) (PMMA) resin and the Si3N4 powder may be present in a concentration of about 1 vol.% to about 30 vol.% in the thermoplastic polymer.

IPC Classes  ?

• A01N 59/00 - Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
• A61K 6/802 - Preparations for artificial teeth, for filling teeth or for capping teeth comprising ceramics
• A61K 6/887 - Compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
• C01B 21/068 - Binary compounds of nitrogen with metals, with silicon, or with boron with silicon

Abstract

34344 powder may be present in a concentration of about 1 vol.% to about 30 vol.% in the thermoplastic polymer.

IPC Classes  ?

• A01N 59/00 - Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
• A61K 6/802 - Preparations for artificial teeth, for filling teeth or for capping teeth comprising ceramics
• A61K 6/887 - Compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
• C01B 21/068 - Binary compounds of nitrogen with metals, with silicon, or with boron with silicon

Abstract

Disclosed herein are methods for functionalizing the surface of a biomedical implant. The biomedical implant may be a zirconia-toughened alumina implant surface functionalized with silicon nitride powder for promoting osteogenesis.

IPC Classes  ?

• A61L 27/10 - Ceramics or glasses
• A61L 27/54 - Biologically active materials, e.g. therapeutic substances
• A61F 2/28 - Bones
• C04B 35/584 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on borides, nitrides or silicides based on silicon nitride

Abstract

Disclosed herein are methods for functionalizing the surface of a biomedical implant. The biomedical implant may be a zirconia-toughened alumina implant surface functionalized with silicon nitride powder for promoting osteogenesis.

IPC Classes  ?

• A61F 2/28 - Bones
• A61L 27/10 - Ceramics or glasses
• A61L 27/54 - Biologically active materials, e.g. therapeutic substances
• C04B 35/584 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on borides, nitrides or silicides based on silicon nitride

Abstract

Methods for improving the antibacterial characteristics of biomedical implants and related implants manufactured according to such methods. In some implementations, a biomedical implant comprising a silicon nitride ceramic material may be subjected to a surface roughening treatment so as to increase a surface roughness of at least a portion of the biomedical implant to a roughness profile having an arithmetic average of at least about 500 nm Ra. In some implementations, a coating may be applied to a biomedical implant. Such a coating may comprise a silicon nitride ceramic material, and may be applied instead of, or in addition to, the surface roughening treatment process.

IPC Classes  ?

• A61L 31/02 - Inorganic materials
• A61L 31/16 - Biologically active materials, e.g. therapeutic substances
• A61L 31/12 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material
• A61L 31/08 - Materials for coatings
• A61L 27/30 - Inorganic materials
• A61L 31/14 - Materials characterised by their function or physical properties
• A61L 27/50 - Materials characterised by their function or physical properties
• A61L 27/06 - Titanium or titanium alloys

Goods & Services

Artificial ceramic material that promotes the in-growth and/or attachment of an implant to tissue by biological, mechanical, chemical and/or physical means used in the manufacture of orthopedic implants Artificial ceramic material that promotes the in-growth and/or attachment of an implant to tissue by biological, mechanical, chemical and/or physical means sold as a component of orthopedic implants

Abstract

Disclosed herein are compositions, devices and methods for inactivating viruses, bacteria, and fungi. The compositions, methods, and devices may include coatings or slurries such as silicon nitride powder coatings or slurries for the inactivation of viruses, bacteria, and/or fungi.

IPC Classes  ?

• A23L 3/26 - Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by irradiation without heating
• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor
• A61L 2/08 - Radiation

Abstract

Disclosed herein are compositions, devices and methods for inactivating viruses, bacteria, and fungi. The compositions, methods, and devices may include coatings or slurries such as silicon nitride powder coatings or slurries for the inactivation of viruses, bacteria, and/or fungi.

IPC Classes  ?

• A23L 3/26 - Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by irradiation without heating
• A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor
• A61L 2/08 - Radiation

Abstract

Disclosed herein are compositions, devices and methods for inactivating viruses, bacteria, and fungi. The compositions, methods, and devices may include coatings or slurries such as silicon nitride powder coatings or slurries for the inactivation of viruses, bacteria, and/or fungi.

IPC Classes  ?

• C01B 21/068 - Binary compounds of nitrogen with metals, with silicon, or with boron with silicon
• A01N 59/02 - SulfurSeleniumTelluriumCompounds thereof
• A01N 25/32 - Ingredients for reducing the noxious effect of the active substances to organisms other than pests, e.g. toxicity reducing compositions, self-destructing compositions
• A01C 1/06 - Coating or dressing seed

Abstract

Methods for improving the wear performance of silicon nitride and/or other ceramic materials, particularly to make them more suitable for use in manufacturing biomedical implants.

IPC Classes  ?

• C04B 35/597 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on borides, nitrides or silicides based on silicon oxynitrides
• C04B 35/58 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on borides, nitrides or silicides
• C04B 35/599 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on borides, nitrides or silicides based on silicon oxynitrides based on silicon aluminium oxynitrides [SiAlON]

Abstract

Methods for improving the antibacterial characteristics of biomedical implants and related implants manufactured according to such methods. In some implementations, a biomedical implant comprising a silicon nitride ceramic material may be subjected to a surface roughening treatment so as to increase a surface roughness of at least a portion of the biomedical implant to a roughness profile having an arithmetic average of at least about 500 nm Ra. In some implementations, a coating may be applied to a biomedical implant. Such a coating may comprise a silicon nitride ceramic material, and may be applied instead of, or in addition to, the surface roughening treatment process.

IPC Classes  ?

• A61L 27/10 - Ceramics or glasses
• A61L 27/44 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
• A61L 27/50 - Materials characterised by their function or physical properties
• A61L 27/54 - Biologically active materials, e.g. therapeutic substances
• C04B 35/58 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on borides, nitrides or silicides
• C04B 35/597 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on borides, nitrides or silicides based on silicon oxynitrides
• C04B 35/599 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on borides, nitrides or silicides based on silicon oxynitrides based on silicon aluminium oxynitrides [SiAlON]

Abstract

Methods for improving the antibacterial, osteoconductive, and/or osteoinductive characteristics of silicon nitride and/or other ceramic materials, particularly to make them more suitable for use in manufacturing biomedical implants. In some embodiments and implementations, the surface chemistry and/or morphology of a silicon nitride bioceramic may be modulated significantly through thermal, chemical, and/or mechanical treatments to achieve such advantageous results. A portion of the resulting material, such as a glaze or upper layer of the material, may be separately produced as a powder or frit, for example, and used in manufacturing biomedical implants and/or other products, such as by using such portion of the material as a coating or filler. In other embodiments the surface material may be separately manufactured as a silicon oxynitride monolith.

IPC Classes  ?

• A61L 27/02 - Inorganic materials
• C23C 16/56 - After-treatment
• C04B 35/597 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on borides, nitrides or silicides based on silicon oxynitrides
• A61L 27/54 - Biologically active materials, e.g. therapeutic substances
• A61L 27/10 - Ceramics or glasses
• A61L 27/30 - Inorganic materials
• A61L 27/50 - Materials characterised by their function or physical properties
• A61L 27/44 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material having a macromolecular matrix

Goods & Services

Spinal implants composed of artificial material; surgical instruments for use in spinal surgery.

Goods & Services

spinal implants composed of artificial material [ ; surgical instruments for use in spinal surgery ]

Abstract

Ceramic orthopedic implants may have one or more dense inner layers and one or more porous outer layers. Methods for manufacturing the implants may include one or more stages during which the dense inner layer(s) are partially compressed. At least one porous outer layer may include coating particles that are present at a surface of one or more inner layer(s) while pressure is applied to attach the coating particles to the inner layer(s) and to further compress one or more of the inner layer(s). Various layers may be formed until an implant, or other device, is formed having the desired density gradient and/or other properties, as disclosed herein.

IPC Classes  ?

• A61F 2/34 - Acetabular cups
• A61F 2/30 - Joints
• C04B 35/584 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on non-oxides based on borides, nitrides or silicides based on silicon nitride
• C04B 38/00 - Porous mortars, concrete, artificial stone or ceramic warePreparation thereof
• B28B 3/00 - Producing shaped articles from the material by using pressesPresses specially adapted therefor

Abstract

Ceramic implants, such as spinal implants, may comprise a dense shell and a porous core. In some implementations, methods for manufacturing the implants may comprise one or more stages at which the core material abuts the shell so as to form a mechanical attachment therewith while both the core and the shell are in a green state. The core and the shell may be fired together, and the resultant implant may, in some embodiments, comprise a unitary piece of ceramic material. Some embodiments may comprise silicon nitride ceramic materials.

IPC Classes  ?

• A61F 2/44 - Joints for the spine, e.g. vertebrae, spinal discs
• A61F 2/30 - Joints

Abstract

Embodiments of apparatus, systems, and methods relating to biomedical implants and other devices made up of unique and improved alumina-zirconia ceramic materials. In an example of a method according to an implementation of the invention, a slurry is prepared, compressed, and fired to obtain a fired ceramic piece comprising at least aluminum oxide, zirconium dioxide, yttrium oxide, cerium oxide, strontium oxide, magnesium oxide, titanium dioxide, and calcium oxide. Some embodiments and implementations may comprise selected concentrations of one or more such compounds to yield certain preferred results.

IPC Classes  ?

• C04B 35/119 - Composites with zirconium oxide
• C04B 35/10 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxides based on aluminium oxide
• A61L 27/00 - Materials for prostheses or for coating prostheses
• C04B 35/117 - Composites
• C04B 35/44 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxides based on aluminates
• C04B 35/626 - Preparing or treating the powders individually or as batches
• C04B 35/645 - Pressure sintering
• A61L 27/10 - Ceramics or glasses

Abstract

5. Certain embodiments and implementations may comprise particular, unique concentrations or concentration ranges of various compounds/materials in order to improve performance for use of such ceramic materials as biomedical implants.

IPC Classes  ?

• C04B 35/119 - Composites with zirconium oxide
• C04B 35/505 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on rare earth compounds based on yttrium oxide
• C04B 35/64 - Burning or sintering processes
• C04B 35/117 - Composites
• C04B 35/44 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxides based on aluminates
• C04B 35/626 - Preparing or treating the powders individually or as batches
• C04B 35/645 - Pressure sintering
• A61L 27/10 - Ceramics or glasses

Abstract

Methods for threading ceramic materials, such as ceramic materials used for spinal implants or other biomedical implants. In some implementations, an expected rate of shrinkage of the block upon undergoing a firing process may be determined. A scaling factor may then be applied using the expected rate of shrinkage to select a tap having a size larger than a desired thread size. A green block may then be tapped with the selected tap to form a threaded opening in the green block. The block may be machined in order to remove cracks caused by the tapping process and/or to form the block into a desired shape/size. The green block may then be fired, which may result in a reduction of a size of the block and a size of the threaded opening.

IPC Classes  ?

• B28B 11/08 - Apparatus or processes for treating or working the shaped articles for reshaping the surface, e.g. smoothing, roughening, corrugating, making screw-threads
• B28B 17/00 - Details of, or accessories for, apparatus for shaping the materialAuxiliary measures taken in connection with such shaping
• A61L 27/10 - Ceramics or glasses

Abstract

Methods, apparatus, and systems for improving the performance of articulating prostheses. Some embodiments may comprise a first component comprising a first articulating surface and a second component comprising a second articulating surface configured for articulating with the first articulating surface. One or both of the first and second components may comprise a silicon nitride ceramic material. One or both of the first and second articulating surfaces may comprise a coating that is configured to accomplish at least one of increasing the hardness of the first articulating interface surface, reducing the coefficient of friction between the first and second articulating surfaces, decreasing the effects of wearing between the first and second articulating surfaces, and decreasing the intensity of audible noises produced by the endoprosthesis resulting from articulation between the first and second articulating surfaces during use.

IPC Classes  ?

• A61F 2/30 - Joints
• C23C 14/06 - Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material characterised by the coating material
• A61F 2/32 - Joints for the hip
• C23C 14/48 - Ion implantation
• A61L 27/10 - Ceramics or glasses
• A61L 27/30 - Inorganic materials

Goods & Services

Artificial ceramic materials that promote the in-growth and/or attachment of an implant to tissue by biological, mechanical, chemical and/or physical means used in orthopaedic implants, being materials (or ingredients) to be used by specialists.

Goods & Services

Ceramic material used in orthopedic implants.