42 - Scientific, technological and industrial services, research and design
Goods & Services
Providing on-line non-downloadable software for identifying, collecting, organizing, managing, analyzing, visualizing, synthesizing, and reporting scientific, clinical, and real-world evidence in the life sciences and healthcare fields, namely for structured data extraction, data validation, statistical modeling, comparative effectiveness analysis, meta-analysis, network meta-analysis, sensitivity analysis, subgroup analysis, and generation of reports for regulatory, reimbursement, and health technology assessment purposes; Providing on-line non-downloadable software for identifying, collecting, organizing, managing, analyzing, visualizing, synthesizing, and reporting scientific, clinical, and real-world evidence in the life sciences and healthcare fields, namely for literature searching, systematic and targeted literature review management, study screening and selection
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Downloadable software for use in statistical analysis and
forecasting for use in planning, implementing and monitoring
clinical trials and user manuals sold together therewith. Providing temporary use of non-downloadable cloud-based
software for use in statistical analysis and forecasting for
the planning, implementing, and monitoring of clinical
trials and/or the creation and implementation of formulated
decision guidelines for use in clinical development;
providing temporary use of non-downloadable cloud-based
software for the creation and implementation of formulated
decision guidelines for use in clinical development;
software as a service (SaaS) services featuring software for
use by product development teams at pharmaceutical and
biotech companies, nonprofit, government or academic
institutions, and others to forecast patient enrollment in
clinical trials and communicate recommendations to decision
makers; platform as a service (PaaS) featuring computer
software platforms for use by product development teams at
pharmaceutical and biotech companies to plan and monitor
clinical trials and communicate recommendations to
management and governance boards.
3.
SYSTEMS AND METHODS FOR SYSTEMATIC LITERATURE REVIEW
Publication pre-screening may include the use of a trained model. A trained language model may be fine-tuned on a question-and-answer task and may be configured to receive a question that includes inclusion and exclusion criteria for a publication. The question may be formulated to include context information such as a title and abstract of the publication. An output of the model may be used to determine a selection of the publication.
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Downloadable software for use in statistical analysis and forecasting for use in planning, implementing and monitoring clinical trials and user manuals sold together therewith Providing temporary use of non-downloadable cloud-based software for use in statistical analysis and forecasting for the planning, implementing, and monitoring of clinical trials and/or the creation and implementation of formulated decision guidelines for use in clinical development; Providing temporary use of non-downloadable cloud-based software for the creation and implementation of formulated decision guidelines for use in clinical development; Software as a service (SAAS) services featuring software for use by product development teams at pharmaceutical and biotech companies, nonprofit, government or academic institutions, and others to forecast patient enrollment in clinical trials and communicate recommendations to decision makers; Platform as a service (PAAS) featuring computer software platforms for use by product development teams at pharmaceutical and biotech companies to plan and monitor clinical trials and communicate recommendations to management and governance boards
A method for determining trial designs that includes obtaining simulation data for a set of trial designs that includes combinations of design options for a set of criteria. The simulation data includes performance parameters and performance parameter values associated with each design in the set of trial designs for the set of criteria. The method further includes determining an optimality criteria for evaluating the trial designs. The optimality criteria includes at least one of Pareto optimality or convex hull optimality for clinical trial design performance values. The method further includes: determining at least one of a cooling cycle, a parameter change, or a direction; and searching, within the set of trial designs, for a set of globally optimum designs based on the optimality criteria using simulated annealing. The simulated annealing is based at least in part on at least one of the cooling cycle, the parameter change, or the direction.
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
G06F 30/12 - Geometric CAD characterised by design entry means specially adapted for CAD, e.g. graphical user interfaces [GUI] specially adapted for CAD
G06F 30/20 - Design optimisation, verification or simulation
G06F 111/02 - CAD in a network environment, e.g. collaborative CAD or distributed simulation
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
42 - Scientific, technological and industrial services, research and design
Goods & Services
Providing temporary use of non-downloadable cloud-based
software for use in statistical analysis for the planning,
implementing, and monitoring of clinical trials and/or the
creation and implementation of formulated decision
guidelines for use in clinical development; software as a
service (SAAS) services featuring software for use by
product development teams at pharmaceutical and biotech
companies, nonprofit, government or academic institutions,
and others to design clinical trials and communicate study
design recommendations to decision makers.
A method for searching clinical trial designs that includes: determining a first convex hull set from a first set of clinical trial designs for a first scenario; simulating the first convex hull set for a second scenario to determine first simulation results; removing the first convex hull set from the first set of clinical trial designs to generate a second set of clinical trial designs; determining a second convex hull set from the second set of clinical trial designs for the first scenario; simulating the second convex hull set for the second scenario to determine second simulation results; determining, based at least in part on the first simulation results and the second simulation results, a refined scenario convex hull set of clinical trial designs for the second scenario from the first convex hull set and the second convex hull set; and transmitting the refined scenario convex hull set.
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
G06F 30/12 - Geometric CAD characterised by design entry means specially adapted for CAD, e.g. graphical user interfaces [GUI] specially adapted for CAD
G06F 30/20 - Design optimisation, verification or simulation
G06F 111/02 - CAD in a network environment, e.g. collaborative CAD or distributed simulation
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
A method for determining trial designs is provided. The method includes receiving, via at least one processor, one or more trial design criteria and one or more scenarios corresponding to a set of trial designs, and generating, via the at least one processor, simulation data based at least in part on replicating each of the set of trial designs with the one or more trial design criteria and the one or more scenarios. The simulation data includes performance parameters and performance parameter values associated with each design in the set of designs for a set of criteria. The method further includes determining, via the at least one processor, an optimality criteria for evaluating the trial designs, searching, within the set of trial designs, via the at least one processor, for globally optimum designs based on the optimality criteria, and transmitting, via the at least one processor, globally optimum designs.
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
G06F 30/12 - Geometric CAD characterised by design entry means specially adapted for CAD, e.g. graphical user interfaces [GUI] specially adapted for CAD
G06F 30/20 - Design optimisation, verification or simulation
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
G06F 111/02 - CAD in a network environment, e.g. collaborative CAD or distributed simulation
42 - Scientific, technological and industrial services, research and design
Goods & Services
Providing temporary use of non-downloadable cloud-based software for use in statistical analysis for the planning, implementing, and monitoring of clinical trials and/or the creation and implementation of formulated decision guidelines for use in clinical development; Software as a service (SAAS) services featuring software for use by product development teams at pharmaceutical and biotech companies, nonprofit, government or academic institutions, and others to design clinical trials and communicate study design recommendations to decision makers
42 - Scientific, technological and industrial services, research and design
Goods & Services
Consulting services in the fields of biotechnology,
pharmaceutical research and development and genetic science;
consulting services in the fields of biotechnology,
pharmaceutical research and development, laboratory genetic
testing, medical diagnostic testing, and pharmacogenetics;
pharmaceutical research services; pharmaceutical research
and development; platform as a service (paas) featuring
computer software platforms for conducting pharmaceutical
research; providing medical and scientific research
information in the field of pharmaceuticals and clinical
trials; providing medical and scientific research
information in the fields of pharmaceuticals and genetics;
research and development in the pharmaceutical and
biotechnology fields; research on the subject of
pharmaceuticals; technical research in the field of
pharmaceutical studies; testing, inspection or research of
pharmaceuticals, cosmetics or foodstuff; testing,
inspection, research, or development of pharmaceutical
preparations for gene therapy; providing on-line
nondownloadable software for conducting pharmaceutical
research.
11.
Systems and methods for systematic literature review
Publication pre-screening may include the use of a trained model. A trained language model may be fine-tuned on a question-and-answer task and may be configured to receive a question that includes inclusion and exclusion criteria for a publication. The question may be formulated to include context information such as a title and abstract of the publication. An output of the model may be used to determine a selection of the publication.
Publication pre-screening may include the use of a trained model. A trained language model may be fine-tuned on a question-and-answer task and may be configured to receive a question that includes inclusion and exclusion criteria for a publication. The question may be formulated to include context information such as a title and abstract of the publication. An output of the model may be used to determine a selection of the publication.
42 - Scientific, technological and industrial services, research and design
Goods & Services
Consulting services in the fields of biotechnology, pharmaceutical research and development and genetic science; Consulting services in the fields of biotechnology, pharmaceutical research and development, laboratory genetic testing, medical diagnostic testing, and pharmacogenetics; Pharmaceutical research services; Pharmaceutical research and development; Platform as a service (PAAS) featuring computer software platforms for conducting pharmaceutical research; Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; Providing medical and scientific research information in the fields of pharmaceuticals and genetics; Research and development in the pharmaceutical and biotechnology fields; Research on the subject of pharmaceuticals; Technical research in the field of pharmaceutical studies; Testing, inspection or research of pharmaceuticals, cosmetics or foodstuff; Testing, inspection, research, or development of pharmaceutical preparations for gene therapy; Providing on-line nondownloadable software for conducting pharmaceutical research
14.
DESIGN STRATIFICATION FOR EVALUATION OF QUALITATIVE TRADEOFFS
An apparatus for evaluating qualitative aspects of design includes identifying a plurality of design variables and ordering values of the plurality of design variables according to a preference. The method further includes assigning a level value to each value of the plurality of design variables according to the ordering, generating a stratification geometry using the assigned level values, and comparing designs using the stratification geometry
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
A method, according to some implementations, receiving, for each trial design of a set of trial designs, a simulated performance and presenting, for at least two criteria, a plot of the simulated performance. The method may further include presenting, for at least one additional criteria, a plurality of contour lines on the plot and selecting a subset of the set of trial designs based on the plurality of contour lines.
A method for trial design analysis that includes receiving, for each trial design of a plurality of trial designs, a set of simulated performance criteria for a set of trial designs, and visualizing, on a graph, values for a first simulated performance criteria and a second simulated performance criteria from the set of simulated performance criteria for each trial design using a location of points on the graph corresponding to the set of trial designs. The method further includes identifying optimal designs based on an optimality criteria using the set of the simulated performance criteria, and determining a tradeoff metric for the first simulated performance criteria and the second simulated performance criteria. The method further includes displaying, the tradeoff metric as a set of lines on the graph, wherein a slope of the lines corresponds to a value of the tradeoff metric.
G06F 30/12 - Geometric CAD characterised by design entry means specially adapted for CAD, e.g. graphical user interfaces [GUI] specially adapted for CAD
G06F 30/20 - Design optimisation, verification or simulation
A method and system including identifying, via at least one processor, a user role; configuring, via the at least one processor, an interface for the user role, wherein configuring the interface includes determining an interface view for the user role; and displaying, via the at least one processor, the interface with the interface view.
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
G06F 30/20 - Design optimisation, verification or simulation
G06Q 10/06 - Resources, workflows, human or project managementEnterprise or organisation planningEnterprise or organisation modelling
G06F 30/12 - Geometric CAD characterised by design entry means specially adapted for CAD, e.g. graphical user interfaces [GUI] specially adapted for CAD
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
42 - Scientific, technological and industrial services, research and design
Goods & Services
Platform as a service (PAAS) featuring computer software platforms for use by product development teams at pharmaceutical and biotech companies to design clinical trials and communicate study design recommendations to management and governance boards; Providing temporary use of non-downloadable cloud-based software for the creation and implementation of formulated decision guidelines for use in clinical development
42 - Scientific, technological and industrial services, research and design
Goods & Services
Consulting services in the fields of biotechnology, pharmaceutical research and development and genetic science; Consulting services in the fields of biotechnology, pharmaceutical research and development, laboratory genetic testing, medical diagnostic testing, and pharmacogenetics; Pharmaceutical research services; Pharmaceutical research and development; Platform as a service (PAAS) featuring computer software platforms for conducting pharmaceutical research; Providing medical and scientific research information in the field of pharmaceuticals and clinical trials; Providing medical and scientific research information in the fields of pharmaceuticals and genetics; Research and development in the pharmaceutical and biotechnology fields; Research on the subject of pharmaceuticals; Technical research in the field of pharmaceutical studies; Testing, inspection or research of pharmaceuticals, cosmetics or foodstuff; Testing, inspection, research, or development of pharmaceutical preparations for gene therapy; Providing on-line non-downloadable software for conducting pharmaceutical research
20.
METHODS AND SYSTEM FOR REDUCING COMPUTATIONAL COMPLEXITY OF CLINICAL TRIAL DESIGN SIMULATIONS
A method, according to some implementations, includes generating a plurality of base datasets using a random number generator and determining scenario specifications. The method may further include identifying at least one transformation function for at least one of the plurality of base datasets based on the scenario specifications and transforming the at least one of the plurality of base datasets using the at least one transformation function. In some cases, the method may also include generating scenario parameters based on the at least one transformed datasets.
G06F 30/27 - Design optimisation, verification or simulation using machine learning, e.g. artificial intelligence, neural networks, support vector machines [SVM] or training a model
G06K 9/62 - Methods or arrangements for recognition using electronic means
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
A method for determining trial designs is provided. The method includes obtaining simulation data for a set of trial designs. The simulation data includes performance parameters and performance parameter values associated with each design in the set of designs for a set of criteria; determining an optimality criteria for evaluating the trial designs; searching, within the set of trial designs, for globally optimum designs based on the optimality criteria; and recommending globally optimum designs.
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
G06F 30/12 - Geometric CAD characterised by design entry means specially adapted for CAD, e.g. graphical user interfaces [GUI] specially adapted for CAD
G06F 30/20 - Design optimisation, verification or simulation
G06F 111/02 - CAD in a network environment, e.g. collaborative CAD or distributed simulation
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
A method for determining trial designs is provided. The method includes receiving, via at least one processor, one or more trial design criteria and one or more scenarios corresponding to a set of trial designs, and generating, via the at least one processor, simulation data based at least in part on replicating each of the set of trial designs with the one or more trial design criteria and the one or more scenarios. The simulation data includes performance parameters and performance parameter values associated with each design in the set of designs for a set of criteria. The method further includes determining, via the at least one processor, an optimality criteria for evaluating the trial designs, searching, within the set of trial designs, via the at least one processor, for globally optimum designs based on the optimality criteria, and transmitting, via the at least one processor, globally optimum designs.
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
G06F 30/12 - Geometric CAD characterised by design entry means specially adapted for CAD, e.g. graphical user interfaces [GUI] specially adapted for CAD
G06F 30/20 - Design optimisation, verification or simulation
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
G06F 111/02 - CAD in a network environment, e.g. collaborative CAD or distributed simulation
A method, according to some implementations, includes obtaining trial design simulation results for a set of trial designs and determining a set of Pareto designs in the set of trial designs based at least in part on the trial design simulation results and one or more performance parameters. The method further includes determining a set of convex hull designs in the set of trial designs, determining a set of recommended designs based at least in part on the set of Pareto designs and the set of convex hull designs, and transmitting the set of recommended designs.
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
G06F 30/12 - Geometric CAD characterised by design entry means specially adapted for CAD, e.g. graphical user interfaces [GUI] specially adapted for CAD
G06F 30/20 - Design optimisation, verification or simulation
G06F 111/02 - CAD in a network environment, e.g. collaborative CAD or distributed simulation
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
A method for trial design with pareto techniques is provided. The method includes obtaining trial design simulation results for a set of trial designs and determining a score for each trial design based on a performance criteria. The method further includes evaluating Pareto optimality for each design in the set of trial designs to determine a Pareto frontier, filtering designs that are not on the Pareto frontier, and communicating the Pareto frontier designs.
G06F 30/20 - Design optimisation, verification or simulation
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
A method, according to some implementations, includes displaying an interface structured to evaluate design data by a group of users and identifying user parameters for each user in the group. The method ma further include configuring the interface for each user in the group based at least in part on the user parameters, receiving, via the interface, user input data from one or more users in the group, and scoring designs based on the user input and user parameters.
G06F 30/20 - Design optimisation, verification or simulation
G06F 30/12 - Geometric CAD characterised by design entry means specially adapted for CAD, e.g. graphical user interfaces [GUI] specially adapted for CAD
A method for trial design with simulated annealing includes obtaining, via at least one processor of a trial design platform, initial trial design simulation results data for a set of trial designs. The method may further include identifying an initial design from the design simulation results data, predicting, performance data of designs for variations of parameters corresponding to the set of trial designs, and identifying a new design for simulation by varying parameters of the initial simulated design based on the predicting. The method may also include simulating the new design, determining performance data of the new design, and identifying a second new design for simulation by varying parameters of the new design based on the simulated performance of the new design.
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
G06F 30/27 - Design optimisation, verification or simulation using machine learning, e.g. artificial intelligence, neural networks, support vector machines [SVM] or training a model
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
A method for determining trial designs is provided. The method includes obtaining simulation data for a set of trial designs. The simulation data includes performance parameters and performance parameter values associated with each design in the set of designs for a set of criteria. The method further includes determining an optimality criteria for evaluating the trial designs, searching, within the set of trial designs, for globally optimum designs based on the optimality criteria; and recommending globally optimum designs.
A method, according to some implementations, includes obtaining a criteria for a trial design study, determining permutations for designs in response to the criteria, and determining permutations for scenarios in response to the criteria. The method may further include generating combinations of the permutations for the designs and the permutations for the scenarios, simulating designs corresponding to the generated combinations, and determining performance of the simulated designs.
G06F 30/20 - Design optimisation, verification or simulation
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
G06F 30/12 - Geometric CAD characterised by design entry means specially adapted for CAD, e.g. graphical user interfaces [GUI] specially adapted for CAD
A method, according to some implementations, includes obtaining trial design simulation results for a set of trial designs and determining a score for each trial design based on a performance criteria. The method may further include evaluating the designs in the set of trial designs to determine a convex hull for the set of trial designs, filtering designs based on the convex hull, and communicating the convex hull designs.
G06F 30/20 - Design optimisation, verification or simulation
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
A method, according to some implementations, includes determining, via at least one processor, a plurality of possible sites for recruiting patients from for a trial and determining, via the at least one processor and for each of one or more subgroupings of the plurality of possible sites, a predicted patient recruitment value. The method may include determining, via the at least one processor, a candidate subgrouping of the plurality of possible sites having a predicted patient recruitment value that globally optimizes a desired site selection criteria, and transmitting, via the at least one processor, data corresponding to the candidate subgrouping.
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
G06Q 30/02 - MarketingPrice estimation or determinationFundraising
G06Q 10/06 - Resources, workflows, human or project managementEnterprise or organisation planningEnterprise or organisation modelling
A method, according to some implementations, includes receiving, via at least one processor, output data of a plurality of trial design simulations for a plurality of scenarios and evaluating, via the at least one processor, the output data to determine changes in performance over the plurality of scenarios. The method may further include generating, via the at least one processor, visual tornado diagram data structured to generate a visual tornado diagram on an electronic display of an electronic device and transmitting, via the at least one processor, the visual tornado diagram data to the electronic device.
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
A method, according to some implementations, includes providing inputs to a plurality of trial design simulation engines, receiving first outputs of the plurality of trial design simulation engines in response to the inputs, and providing variations of the inputs to the plurality of trial design simulation engines. The method may further include receiving second outputs of the plurality of trial design simulation engines in response to the variations evaluating the first and the second outputs to determine delta values, and determining, based in part on the delta values, a plurality of normalization factors for the plurality of trial design simulation engines.
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
G06Q 10/06 - Resources, workflows, human or project managementEnterprise or organisation planningEnterprise or organisation modelling
A method for trial design includes presenting on a graphical interface, a set of cards, wherein each card in the set is representative of a different trial design from a set of trial designs. The method further includes: monitoring a first set of user interactions with the set of cards; determining a user preference for one or more values of one or more parameters of the set of trial designs from the first set of user interactions; and presenting on the graphical interface a new card that is representative of a trial design consistent with the determined user preference. The method may also include monitoring a second set of user interactions with the new card and refining the determined user preference based at least in part on the second set of user interactions with the new card.
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
G06F 30/27 - Design optimisation, verification or simulation using machine learning, e.g. artificial intelligence, neural networks, support vector machines [SVM] or training a model
G06Q 10/067 - Enterprise or organisation modelling
G06Q 10/101 - Collaborative creation, e.g. joint development of products or services
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
G06F 3/0484 - Interaction techniques based on graphical user interfaces [GUI] for the control of specific functions or operations, e.g. selecting or manipulating an object, an image or a displayed text element, setting a parameter value or selecting a range
G06F 111/06 - Multi-objective optimisation, e.g. Pareto optimisation using simulated annealing [SA], ant colony algorithms or genetic algorithms [GA]
42 - Scientific, technological and industrial services, research and design
Goods & Services
Platform as a service (PAAS) featuring computer software platforms for use by product development teams at pharmaceutical and biotech companies to design clinical trials and communicate study design recommendations to management and governance boards; Providing temporary use of non-downloadable cloud-based software for the creation and implementation of formulated decision guidelines for use in clinical development
42 - Scientific, technological and industrial services, research and design
Goods & Services
medical scientific research, namely, providing clinical trial services for others, namely, planning, design, simulation and execution of the clinical trials of others; medical and scientific research clinical trial services for others, namely, analysis of the results of medical and scientific research clinical trials for others
09 - Scientific and electric apparatus and instruments
Goods & Services
Computer programs for use in statistical analysis for use in planning, implementing and monitoring clinical trials and user manuals sold together therewith
