Abstract

The invention discloses a process for fabricating a biomaterial, comprising: a) joining a porous collagen based-material with a non-porous collagen based- material by applying a controlled amount of a bonding layer of a gel comprising collagen to a bonding surface of the non-porous collagen based-material, and contacting a surface of the porous collagen based-material with the gel applied to the bonding surface to partially hydrate a section of the porous material at the interface between the materials; b)drying the gel to dry to bond the materials together; and c)cross-linking the collagens in the bonding layer. Also disclosed are biomaterials and implants produced using the fabrication process.

IPC Classes  ?

• C09J 189/06 - Products derived from waste materials, e.g. horn, hoof or hair derived from leather or skin
• A61L 24/04 - Surgical adhesives or cementsAdhesives for colostomy devices containing macromolecular materials
• A61L 24/10 - PolypeptidesProteins
• A61L 27/38 - Animal cells

Abstract

An implant delivery device (10) comprises a barrel (20), a plunger (30) and an inner sleeve (130) which comprises material stress means (140). The plunger is adapted to fit into a central bore of the inner sleeve in a sliding relationship and the inner sleeve in turn is adapted to fit into the bore of the barrel also in a sliding relationship. An alternative embodiment of the device generally comprises a barrel (20) and plunger (30) and an implant (100) loaded within the barrel, and a column of liquid (110) located proximally behind the implant. A user depressing plunger exerts a compression force on liquid, which is transferred onto the implant and the implant moves distally. along the barrel toward the distal end (50).

IPC Classes  ?

• A61F 2/46 - Special tools for implanting artificial joints

Abstract

A substantially elastic or viscoelastic porous biomaterial, the biomaterial comprising at least one selected from the group consisting of: a synthetic or natural polymer, a ceramic, a metal, an extracellular matrix protein, a calcium phosphate material or an analogue thereof characterised in that the biomaterial is under stress and is in a fully or partially-deformed state. Also disclosed are methods of seeding the biomaterial with cells and methods of treatment and tissue engineering using the elastic biomaterial.

IPC Classes  ?

• A61L 27/46 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
• A61L 27/56 - Porous or cellular materials