A system includes a sensor applicator, a sensor control device arranged within the sensor applicator and including an electronics housing and a sensor extending from a bottom of the electronics housing, and a cap coupled to one of the sensor applicator and the sensor control device, wherein the cap is removable prior to deploying the sensor control device from the sensor applicator.
A lead for an implantable medical device (IMD) includes an electrode having a plurality of brick segments that are discrete and mechanically connected to one another in a line. The brick segments are electrically conductive and electrically connected to one another. The brick segments are configured to be powered by a pulse generator of the IMD to deliver high-voltage shocks for defibrillation therapy.
A system for disrupting calcium within a blood vessel includes a handle, a balloon catheter extending from the handle, a balloon positioned at a distal end portion of the balloon catheter, and a fluid reservoir in fluid communication with a lumen, the lumen being in fluid communication with an interior volume of the balloon. The system also includes a motor operably coupled to the fluid reservoir, and a pressure sensor fluidically in contact with the fluid reservoir and configured to sense a pressure within the balloon. The motor is configured to alternately (i) push fluid from the fluid reservoir through the lumen toward the interior volume of the balloon and (ii) withdraw fluid from the interior volume of the balloon toward the fluid reservoir, so as to cycle between balloon inflation and deflation to repeatedly press the balloon against an interior surface of the blood vessel.
Example embodiments of systems, devices, and methods are described for communication in an analyte monitoring system in accordance with an applicable communication protocol. A first device of the system may transmit a command to a second device of the system and the second device may encounter a processing delay in preparing data responsive to the command. The second device may transmit dummy data to the first device in order to maintain compliance with the communication protocol until such time that the second device is ready to transmit data responsive to the command. Numerous different embodiments for incorporating and/or accommodating the presence of dummy data in a communication hierarchy are provided.
H04B 5/79 - Near-field transmission systems, e.g. inductive or capacitive transmission systems specially adapted for specific purposes for data transfer in combination with power transfer
H04W 4/80 - Services using short range communication, e.g. near-field communication [NFC], radio-frequency identification [RFID] or low energy communication
H04W 12/03 - Protecting confidentiality, e.g. by encryption
Lenses and methods are provided for improving peripheral and/or central vision for patients who suffer from certain retinal conditions that reduce central vision or patients who have undergone cataract surgery. The lens is configured to improve vision by having an optic configured to focus light incident along a direction parallel to an optical axis at the fovea in order to produce a functional foveal image. The optic is configured to focus light incident on the patient's eye at an oblique angle with respect to the optical axis at a peripheral retinal location disposed at a distance from the fovea, the peripheral retinal location having an eccentricity between −30 degrees and 30 degrees. The image quality at the peripheral retinal location is improved by reducing at least one optical aberration at the peripheral retinal location. The method for improving vision utilizes ocular measurements to iteratively adjust the shape factor of the lens to reduce peripheral refractive errors.
A biostimulator transport system includes a sheath having a distal sheath end. The biostimulator transport system includes a deployment tube extending from the distal sheath end to a distal tube end. The biostimulator transport system includes an expandable structure having a ventricle-shaped envelope surrounding the deployment tube. The ventricle-shaped envelope includes a front boundary coupled to the distal tube end and a rear boundary coupled to the distal sheath end. The front boundary and the rear boundary are joined along one or more of a bottom edge and lateral edges.
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61N 1/375 - Constructional arrangements, e.g. casings
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
An implantable biostimulator has a housing, one or more fixation elements at a distal end of the housing, and one or more electrode probes. The housing includes an electronics compartment containing pacing circuitry. The one or more electrode probes are coupled to the pacing circuitry. The one or more electrode probes are extendable from the distal end of the housing. The one or more electrode probes have depth control to a controlled depth of extension.
A system for disrupting calcium within a blood vessel includes a handle, a balloon catheter extending from the handle, a balloon positioned at a distal end portion of the balloon catheter, and a fluid reservoir in fluid communication with a lumen, the lumen being in fluid communication with an interior volume of the balloon. The system also includes a motor operably coupled to the fluid reservoir, and a pressure sensor fluidically in contact with the fluid reservoir and configured to sense a pressure within the balloon. The motor is configured to alternately (i) push fluid from the fluid reservoir through the lumen toward the interior volume of the balloon and (ii) withdraw fluid from the interior volume of the balloon toward the fluid reservoir, so as to cycle between balloon inflation and deflation to repeatedly press the balloon against an interior surface of the blood vessel.
A61B 17/00 - Surgical instruments, devices or methods
A61B 17/22 - Implements for squeezing-off ulcers or the like on inner organs of the bodyImplements for scraping-out cavities of body organs, e.g. bonesSurgical instruments, devices or methods for invasive removal or destruction of calculus using mechanical vibrationsSurgical instruments, devices or methods for removing obstructions in blood vessels, not otherwise provided for
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
9.
SYSTEMS AND METHODS FOR ELECTROPORATION USING WAVEFORMS THAT REDUCE ELECTRICAL STIMULATION
A pulse generator for use with an electroporation system is provided. The pulse generator is configured to be coupled to a catheter including a plurality of electrodes and is configured to generate a waveform to be delivered using at least one of the plurality of electrodes. The waveform includes a pulse train having positive and negative pulses, wherein an average charge over the pulse train is zero.
A computer-implemented method includes measuring, using a first sense channel, a first electrode impedance signal associated with a first electrode. The method further includes measuring, using a second sense channel, a second electrode impedance signal associated with at least a second and third electrode, wherein the second and third electrodes are electrically connected to each other but not to the first electrode. The method further assesses tissue contact/proximity based on the first electrode impedance signal and the second electrode impedance signal.
The invention provides devices, systems and methods for tissue approximation and repair at treatment sites. The devices, systems and methods of the invention will find use in a variety of therapeutic procedures, including endovascular, minimally-invasive, and open surgical procedures, and can be used in various anatomical regions, including the abdomen, thorax, cardiovascular system, heart, intestinal tract, stomach, urinary tract, bladder, lung, and other organs, vessels, and tissues. The invention is particularly useful in those procedures requiring minimally-invasive or endovascular access to remote tissue locations, where the instruments utilized must negotiate long, narrow, and tortuous pathways to the treatment site. In addition, many of the devices and systems of the invention are adapted to be reversible and removable from the patient at any point without interference with or trauma to internal tissues.
A61B 17/00 - Surgical instruments, devices or methods
A61B 17/10 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for applying or removing wound clampsWound clamp magazines
Systems, methods and apparatus are provided for rejecting noise from sparsely sampled analyte sensor data. Embodiments of the present disclosure include receiving a raw set of sensor data from an on-body device including an in vivo analyte sensor, determining an interpolation-based estimate of an analyte level over time based on the raw set of sensor data, determining an extrapolation-based estimate of the analyte level over time based on the raw set of sensor data, determining a combined estimate of the analyte level over time based on the interpolation-based estimate and the extrapolation-based estimate, and displaying a representation of the combined estimate of the analyte level over time on an output device. Numerous additional aspects are disclosed.
Sensor control device for analyte monitoring comprising electronics housing having shell defining top surface and mount defining bottom surface of the electronics housing. Adhesive patch coupled to the bottom surface defines central opening, and includes first layer facing the mount and second layer facing skin of user. The first layer has first aperture, second layer has second aperture, and the first aperture and second aperture align with central opening along vertical axis of the sensor control device. First layer or second layer includes laser cut slots or laser cut holes configured for drainage of fluid or breathability of skin.
Systems, devices, and methods for detecting, measuring and classifying meals for an individual based on analyte measurements. These results and related information can be presented to the individual to show the individual which meals are causing the most severe analyte response. These results can be organized and categorized based on preselected criteria or previous meals and results so as to organize and present the results in a format with reference to glucose as the monitored analyte. Various embodiments disclosed herein relate to methods, systems, and software applications intended to engage an individual by providing direct and timely feedback regarding the individual's meal-related glycemic response.
A leadless biostimulator, such as a leadless cardiac pacemaker, having a header assembly that includes overmolded components, is described. The header assembly includes a helix mount overmolded on a flange of an electrical feedthrough assembly. A fixation element is mounted on the helix mount. The overmolded helix mount fills a recess in an outer surface of the flange to robustly join the header assembly components. The electrical feedthrough assembly includes an electrode contained within the flange to deliver electrical impulses to a target anatomy, and an insulator that separates the electrode from the flange. The overmolded helix mount can conform or adhere to the outer surfaces of the flange and the insulator to electrically isolate the electrode from the flange. Other embodiments are also described and claimed.
An indeflator (1200) for a balloon inflation system, the indeflator having a moving member (1210) and a barrel (1250) having a fluidcontaining portion defining an internal space to receive a fluid. The indeflator is configured to receive a desired fill volume with high accuracy and precision. The filled indeflator can be used to accurately and precisely expand a medical device crimped on an inflatable.
A mold is used to form a solder joint to join the distal end of the guidewire to a wire coil. The mold has a cavity that can have different configurations so that the solder joint can be any of bullet shaped, micro-J shaped, cone shaped, truncated cone shaped, or have a textured surface.
B21F 15/08 - Connecting wire to wire or other metallic material or objectsConnecting parts by means of wire wire with wire with additional connecting elements or material making use of soldering or welding
B22D 18/02 - Pressure casting making use of mechanical pressing devices, e.g. cast-forging
B22D 19/04 - Casting in, on, or around, objects which form part of the product for joining parts
B23K 1/08 - Soldering by means of dipping in molten solder
Described herein are implantable medical devices (IMDs), and methods for use therewith. In certain embodiments, a controller of an IMD controls when a pacing capacitor of the IMD is charged using a first voltage, when the pacing capacitor is being charged using a second voltage, and when the pacing capacitor is discharged to deliver a pacing pulse between anode and cathode electrodes of, or electrically coupled to, the IMD. By selectively charging the pacing capacitor for a portion of a charge duration using the second voltage, that is greater in magnitude than the first voltage that is used for delivering the pacing pulse, a magnitude of a polarization artifact superimposed on an evoked response within a cardiac electrical signal, sensed using a sensing circuit of the IMD, is reduced compared to if the pacing capacitor were instead charged using the first voltage for the entire charge duration.
A medical device manufacturing process can include inserting a hollow shaft having a longitudinally-extending slit into the central lumen of a tubular device body, leaving its distal end protruding beyond the device body. The shaft includes an inner layer of a first material and an outer layer of a second material; the second material melts at a lower temperature than the first material. A sensor stack (14), including alternately-disposed spacing elements (14) and sensors (28), is formed around the protruding segment of the shaft. The spacing elements include an inner layer (34a) of a third material and an outer layer (34b) of a fourth material; the third material melts at a lower temperature than the fourth material. The assembly bonded by heating it above the melting temperatures of the second and third materials but below the those of the first and fourth materials.
A method of conducting a virtual clinic (VC) session between a patient and a clinician to facilitate medical services using a VC cloud computing system is provided. The method comprises receiving video data from a patient controller (PC) device of the patient, the video data including patient gait data of the patient acquired by the PC device during the VC session, identifying, from the received video data, at least one fixed edge in an environment surrounding the patient, determining, based on the at least one identified fixed edge, an amount of camera tilt of the PC device relative to the patient, normalizing anatomical landmark data of the patient gait data by applying a transformation to the anatomical landmark data to compensate for the determined amount of camera tilt, and providing the normalized anatomical landmark data to one or more trained computation models to classify one or more patient gait characteristics.
A shaping tool is used to form a bend in the distal end of a guidewire. The guidewire distal end is inserted through a channel and into a cavity of the shaping tool. Using hand pressure, a fist member is moved axially relative to a second member of the shaping tool, thereby moving the cavity relative to the channel and imparting a bend in the distal end of the guidewire.
A system for managing a patient's glucose level includes a glucose sensor to generate and store data signals for measurements of the patient's glucose level made by the glucose sensor; an insulin pump; and sensor electronics operatively coupled to the glucose sensor, the sensor electronics comprising a memory storing one or more predetermined characteristics associated with the sensor electronics; and a computing device in electronic communication with the sensor electronics. The computing device comprises a processor configured to operate the sensor electronics to (i) receive the generated data signals, (ii) obtain the one or more predetermined sensor characteristics from the memory and (iii) execute a closed-loop algorithm to provide insulin delivery instructions to an insulin pump by at least using the data signals and predetermined characteristics.
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
24.
Valve Repair Clip with Automatic Locking Mechanism Activation
A mitral valve clip includes a stud, a lock, and two arms. The stud includes a shank, and the lock includes a frame relative to which the stud is translatable and into which the shank extends. The lock is able to prevent movement of the stud relative to the lock in at least one direction by locking engagement of the shank. The two arms are connected to the lock and the stud such that an angle between the arms depends on a location of the stud relative to the lock. The locking engagement of the shank that prevents movement of the stud relative to the lock in the at least one direction is only possible when the angle between the arms is below a predefined locking threshold.
This application is generally related to identifying or otherwise programming one or more cycling parameters for operation of an implantable pulse generator to provide a neurostimulation therapy to a patient using a non-paresthesia stimulation pattern. In some embodiments, the cycling parameter is selected by measuring physiological signals during trial stimulation. In other embodiments, multiple cycling parameters are identified for use by the patient using a patient controller device.
A glucose data analysis system includes an on-body unit and a processor. The on-body unit is configured to measure glucose levels of a user. The processor is configured to receive therapy data of the user including glucose data monitored by the on-body unit, analyze daily glucose profiles of the glucose data over an analysis period by a machine learning model, group the daily glucose profiles into two or more patterns based on the analysis performed by the machine learning model, and output a report including identification of the two or more patterns associated with each daily glucose profile. Advantageously the system may identify and visualize patterns of glucose data, identify recurring patterns, identify correlations between patterns and external events (e.g., medication, meals, exercise, sleep, stress, etc.), reduce glycemic variability, streamline analysis with unsupervised machine learning (e.g., no training), and provide recommendations for user intervention or actions based on identified patterns.
G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
27.
SYSTEMS, DEVICES, AND METHODS WITH DURATION-BASED ADJUSTMENT OF SENSOR DATA
Embodiments that compensate for changes to sensor response characteristics (e.g., sensitivity) due to time durations are disclosed. The time durations can be the amount of time the sensor is in a post-manufacture packaged state prior to use, or the amount of time the sensor is in use. Sensor response changes due to other variables can also be compensated for.
A61B 5/1495 - Calibrating or testing in vivo probes
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
28.
METHODS, DEVICES, AND SYSTEMS FOR ADJUSTING LABORATORY HBA1C VALUES
A method of providing personalized treatment for a diabetes patient including a remote device which is configured to receive a first data indicative of an analyte level of a subject during a first time period, retrieve a first glycated hemoglobin level for the subject associated with the first time period, calculate a first personal apparent glycation ratio for the first time period using the received first data and the retrieved first glycated hemoglobin level, compare the calculated first personal apparent glycation ratio to a representative apparent glycation ratio, generate a recommendation based on the comparison, and display a graphical interface comprising the calculated first personal apparent glycation ratio, the representative apparent glycation ratio, and the comparison.
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
ST JUDE MEDICAL INTERNATIONAL HOLDING S.À R.L. (Luxembourg)
Inventor
Izmirli, Alon
Hevel, Guy
Herscovici, Adrian
Vaknin, Yuval
Jacobs, David
Abstract
Aspects of the present disclosure are directed to apparatuses for generating a magnetic field for tracking of a target object. Such an apparatus may include a localized magnetic field transmitter that generates a magnetic field and exhibits minimal X-ray absorption when used in proximity to a fluoroscopic imaging system, for example.
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Providing an Internet website portal featuring information for use by healthcare personnel in the field of electrophysiology medicine, namely, case images, videos, and compiled analytics from external capital equipment, electronic medical records, and patient health records available via a cloud-based repository.
An implantable medical device includes a body and a coating. The body has a metal surface. The coating is deposited on the metal surface of the body. The coating includes a bonding layer and a polymer layer. The bonding layer includes a first layer comprising a first silane coupling agent and a second layer comprising a second silane coupling agent. The first layer is deposited on the metal surface, and the second layer is deposited on the first layer. The polymer layer is deposited on the second layer. The first silane coupling agent is capable of forming a stronger bond with the metal surface of the body than with the polymer layer. The second silane coupling agent is capable of forming a stronger bond with the polymer layer than the metal surface.
Aspects of the disclosure provide a delivery device for a prosthetic heart valve, the delivery device includes a retaining element with a recess arranged to receive a corresponding tab of the prosthetic heart valve. The recess may be shaped to progressively reduce contact with the respective tab as the prosthetic heart valve expands from its collapsed condition to its expanded condition. The recess may include a tapered base. The retaining element may include one or more secondary recesses arranged to receive one or more struts of the prosthetic heart valve. A prosthetic heart valve may also be provided, in which the tab is set at an angle directed away from a plane of struts connecting the tab and/or the tab may include a biasing element arranged to bias the tab away from the recess when the tab is in the recess.
A medical device for occluding a left atrial appendage, LAA, the medical device comprising a single occlusive member configured to occlude an ostium of the LAA in a deployed condition of the medical device, wherein the occlusive member is a disc-shaped portion, and wherein the medical device is configured to be attached only to the ostium of the LAA.
A system for securing tissue includes a fixation device and a piezoelectric sensing system. The fixation device includes a center portion and a first clamp extending from the center portion. The first clamp is comprised of a first proximal element and a first distal element. The piezoelectric sensing system includes a first piezoelectric sensor coupled to one of the first distal element, the first proximal element, and the center portion. A signal processing unit of the sensing system includes a power source and a signal processing module. The signal processing module is configured to receive signals from the first piezoelectric sensor corresponding to a parameter associated with pressure, process the received signals, and generate an output signal indicative of the parameter. An interface is configured to couple the first piezoelectric sensor to the signal processing unit for transmitting the signals from the first piezoelectric sensor to the signal processing unit.
36.
APPARATUS AND METHODS FOR TRANSSEPTAL CATHETERIZATION
A transseptal catheterization apparatus includes an electrically-conductive core, an energy delivery element at the distal end of the core, a coil or insulative filler surrounding at least a portion of the core, and an insulative jacket surrounding at least a portion of the core. The coil may be radially adjacent the core with the insulative jacket surrounding the coil. Alternatively, the insulative jacket may be radially adjacent the core and the coil may surround the insulative jacket. The energy delivery element may be a tip electrode conductively coupled to the core. An insulative bushing may be positioned between the tip electrode and the coil to electrically isolate the tip electrode from the coil. The exterior surface(s) of the energy delivery element and/or the coil may be dimpled or roughened.
A glucose data analysis system includes an on-body unit and a processor. The on-body unit is configured to measure glucose levels of a user. The processor is configured to receive therapy data of the user including glucose data monitored by the on-body unit, analyze daily glucose profiles of the glucose data over an analysis period by a machine learning model, group the daily glucose profiles into two or more patterns based on the analysis performed by the machine learning model, and output a report including identification of the two or more patterns associated with each daily glucose profile. Advantageously the system may identify and visualize patterns of glucose data, identify recurring patterns, identify correlations between patterns and external events (e.g., medication, meals, exercise, sleep, stress, etc.), reduce glycemic variability, streamline analysis with unsupervised machine learning (e.g., no training), and provide recommendations for user intervention or actions based on identified patterns.
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
G16H 15/00 - ICT specially adapted for medical reports, e.g. generation or transmission thereof
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
38.
ANALYTE SENSORS WITH A SENSING SURFACE HAVING SMALL SENSING SPOTS
Embodiments of the present disclosure relate to analyte determining methods and devices (e.g., electrochemical analyte monitoring systems) that have a sensing surface that includes two or more sensing elements disposed laterally to each other, where the sensing surface is on a working electrode of in vivo and/or in vitro analyte sensors, e.g., continuous and/or automatic in vivo monitoring using analyte sensors and/or test strips. Also provided are systems and methods of using the, for example electrochemical, analyte sensors in analyte monitoring.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions
A fixation device for fixation of heart valve leaflets includes a central assembly and an arm moveably coupled to the central assembly. The arm includes a body portion having a first end and a second end and a longitudinal axis defined therebetween. The body portion has opposing body lateral sides, each body lateral side extending between the first end and the second end. Further, the body portion has a body portion width defined between the opposing body lateral sides. The fixation device further includes a size adapter attached to the arm, the size adapter having a maximum undeformed arm lateral cross-dimension defined between outer lateral edges of the size adapter. The ratio between the body portion width and the maximum undeformed arm lateral cross-dimension is at least about 1:1.8 to about 1:2.2. The fixation device further includes at least one gripping element.
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
An implantable medical device is disclosed herein and can be in the form of an implantable medical lead or a leadless pulse generator. The implantable medical device includes a body, at least one electrode and a tube-cut helical fixation anchor. The body includes a distal end and a proximal end opposite the distal end. The at least one electrode is supported on the body. The tube-cut helical fixation anchor distally extends from the distal end. The tube-cut helical fixation anchor may be fixed or extendable/retractable relative to the distal end. The tube-cut helical fixation anchor may be a result of a manufacturing process comprising cutting the tube-cut helical fixation anchor from a thin-walled tubular body.
A system for occluding a left atrial appendage (“LAA”) includes a delivery device and an LAA occluder. The LAA occluder has an indicator electrode coupled to a connector electrode via a conducting wire. The delivery device has a connector with a connector electrode configured to be coupled to a navigation system via a conducting wire. During implantation, the delivery device is coupled to the LAA occluder so that the connector electrodes are electrically coupled, resulting in the indicator electrode being conductively coupled to the navigation system. After the LAA occluder is deployed into the LAA, the delivery device is disconnected from the LAA occluder to allow the LAA occluder to remain in the patient.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/00 - Surgical instruments, devices or methods
42.
FIXATION DEVICES AND SYSTEMS WITH TISSUE CAPTURE INDICATION FEATURES
A fixation device includes a center assembly and first and second clamps extending outwardly from the center assembly. Each clamp includes an anchor member and a gripper disposed opposite the anchor member. The gripper includes an indicator arm and a retention arm. The indicator arm and retention arm are independently moveable between a raised position and an engagement position. The retention arm has a length greater than a length of the indicator arm.
A system for occluding a left atrial appendage ("LAA") includes a delivery device and an LAA occluder. The LAA occluder has an indicator electrode coupled to a connector electrode via a conducting wire. The delivery device has a connector with a connector electrode configured to be coupled to a navigation system via a conducting wire. During implantation, the delivery device is coupled to the LAA occluder so that the connector electrodes are electrically coupled, resulting in the indicator electrode being conductively coupled to the navigation system. After the LAA occluder is deployed into the LAA, the delivery device is disconnected from the LAA occluder to allow the LAA occluder to remain in the patient.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 34/20 - Surgical navigation systemsDevices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
A61B 17/00 - Surgical instruments, devices or methods
A61B 34/10 - Computer-aided planning, simulation or modelling of surgical operations
In some embodiments, a delivery device includes a catheter extending between a proximal end and a distal end, and an inflatable balloon disposed at the distal end of the catheter, the inflatable balloon having an eccentricity of between 0.1 and 0.7 in an inflated state absent external forces.
A balloon-expandable prosthetic heart valve includes a collapsible and expandable stent comprising a plurality of commissure attachment features, and a valve assembly coupled to the collapsible and expandable stent, the valve assembly comprising a plurality of leaflets, an outer cuff configured to promote tissue ingrowth and an inner cuff having an inner surface and an outer surface, the inner surface of the inner cuff having a different ingrowth profile than the outer surface of the inner cuff.
A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
46.
PROSTHETIC VALVES DESIGNED FOR THROMBUS AND IN-VIVO THICKENING
In some embodiments, a prosthetic heart valve, includes a stent having a longitudinal axis, an inner cuff coupled to a luminal surface of the stent, an outer cuff coupled to an abluminal surface of the stent, and a plurality of leaflets coupled to the stent, each of the plurality of leaflets being configured to reduce a risk of hyper-attenuated leaflet thickening.
In some embodiments, a prosthetic heart valve, includes a stent having a longitudinal axis, at least one of an inner cuff and an outer cuff coupled to the stent, the at least one of the inner cuff and the outer cuff having an inflow end, an outflow end and a connecting zone where two side edges extending along the longitudinal axis of the stent are coupled; and a suture pattern coupling the two side edges at the connecting zone, the suture pattern having a set of stitches chosen from horizontal stitches and diagonal stitches.
In some embodiments, a prosthetic heart valve, includes a stent having a plurality of cells and a plurality of commissure attachment features, portions of each of the plurality of commissure attachment features being moveable relative to the plurality of cells, a cuff coupled to the stent, and a plurality of leaflets, the cuff and the plurality of leaflets forming a valve assembly, each of the plurality of leaflets having two leaflet attachment tabs coupled to ones of the plurality of commissure attachment features.
A medical device for occluding a left atrial appendage ("LAA") may include a proximal occluding member to cover an ostium of the LAA and a distal occluding member to be received within a cavity of the LAA. A connecting member may connect the proximal occluding member to the distal occluding member. An occluding material may be uncoupled from the proximal occluding member in a delivery condition of the proximal occluding member, and uncoupled from the distal occluding member in a delivery condition of the distal occluding member, the occluding material configured to at least partially fill and occlude the LAA. In some examples, the distal occluding member is entirely excluded, and the medical device includes other anchoring provisions, such as tethers that latch onto a back wall of the LAA.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
50.
Display screen or portion thereof with graphical user interface
A system for electrical stimulation of a dorsal root ganglion is disclosed. The system comprises a paddle body extending between a proximal end and a distal end; a lead body extending from the proximal end; an electrode array disposed on at least one surface of the paddle body, the electrode array having one or more electrode contacts arranged in a two-dimensional electrode array configuration forming an asymmetrical paddle lead with the electrical stimulation focused in a single direction within a target area of the dorsal root ganglion; and a living hinge formed by the paddle body extending from a first side to a first hinge and from a second side to a second hinge, the first and second hinges each forming a joint configured to bend the paddle body along a contour to cradle the dorsal root ganglion.
Various embodiments of systems, devices and methods for identifying meal start and meal peak response candidates are described. The methods include a set of meal start candidates and meal peak response candidates based on user-initiated analyte checks and analyte data from an analyte monitoring system.
G16H 20/10 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients
G16H 20/60 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to nutrition control, e.g. diets
54.
NUTRITIONAL COMPOSITIONS COMPRISING HUMAN MILK OLIGOSACCHARIDES AND NUCLEOTIDES AND USES THEREOF FOR TREATING AND/OR PREVENTING ENTERIC VIRAL INFECTION
Disclosed are nutritional compositions including human milk oligosaccharides and nucleotides that can be administered to preterm infants, term infants, toddlers, and children for reducing inflammation and the incidence of inflammatory diseases.
A61K 31/702 - Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
A23L 33/00 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof
A23L 33/125 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing carbohydrate syrupsModifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing sugarsModifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing sugar alcoholsModifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives containing starch hydrolysates
A61K 31/7068 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
A61K 31/7072 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
A61K 31/7076 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
A61K 31/708 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid having oxo groups directly attached to the purine ring system, e.g. guanosine, guanylic acid
Systems, devices and methods are provided for inserting at least a portion of an in vivo analyte sensor, such as a dermal sensor, for sensing an analyte level in a bodily fluid of a subject. An applicator is positioned against a skin surface and a force is applied to the applicator causing at least a portion of a sharp and an in vivo analyte sensor to be positioned in the body of the subject. In particular, disclosed herein are embodiments of applicators designed to prevent premature sharp withdrawal and/or reduce the likelihood of improper sensor insertion. Also disclosed are embodiments of applicators including sharp modules having an angled sharp which can be configured to create an insertion path for a sensor.
COMPOSITIONS AND METHODS FOR THE DETECTION AND ANALYSIS OF HERPES SIMPLEX VIRUS 1 (HSV-1), HERPES SIMPLEX VIRUS 2 (HSV-2) AND VARICELLA ZOSTER VIRUS (VZV)
Provided herein are compositions and methods useful for the detection of Herpes Simplex Virus 1 (HSV-1), Herpes Simplex Virus 2 (HSV-2) and Varicella Zoster Virus (VZV). In particular, provided herein are compositions, methods, systems, kits, reagents, and reaction mixtures involving such for nucleic acid amplification and detection procedures that detect HSV-1, HSV-2 and VZV in samples.
C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
B01L 7/00 - Heating or cooling apparatusHeat insulating devices
C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
C12Q 1/6806 - Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
An implantable medical device (IMD) is provided that can include electronic circuitry, a first sensor configured to detect a magnetic field in an environment of the IMD, and a second sensor configured to obtain environmental data. The IMD can also includes one or more processors, and a memory coupled to the one or more processors. The memory stores program instructions, wherein the program instructions are executable by the one or more processors to discriminate between a first magnet mode and a second magnet mode based on the environmental data and switch the mode of operation with the electronic circuitry based on discriminating between the first magnet mode and the second magnet mode.
A transseptal catheterization apparatus includes an electrically-conductive core, an energy delivery element at the distal end of the core, a coil or insulative filler surrounding at least a portion of the core, and an insulative jacket surrounding at least a portion of the core. The coil may be radially adjacent the core with the insulative jacket surrounding the coil. Alternatively, the insulative jacket may be radially adjacent the core and the coil may surround the insulative jacket. The energy delivery element may be a tip electrode conductively coupled to the core. An insulative bushing may be positioned between the tip electrode and the coil to electrically isolate the tip electrode from the coil. The exterior surface(s) of the energy delivery element and/or the coil may be dimpled or roughened.
A medical device is provided in which one or both ends of the device encourage the formation of tissue across substantially the entire area of the respective end that is exposed to the blood flow for reducing the risk of a thrombotic embolism. The medical device includes a tubular structure having at least one expanded volume portion and a tapered transition portion. The tubular structure may be made through the braiding of a number of strands, and a first end feature may be used to secure the proximal strand ends. The proximal strand ends may be secured via the proximal end of the first end feature, such that the tapered transition portion is formed over the circumferential surface of the first end feature, and only a proximal end surface (or a portion of the proximal end surface) of the first end feature is exposed to the path of flowing blood.
A61B 17/00 - Surgical instruments, devices or methods
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A fixation device includes a first distal element and a first proximal element. The first distal element and first proximal element each have a first end and a second end and are moveable relative to each other. First and second electrodes are coupled to either the first distal element or the first proximal element between the first and second ends thereof. The electrodes at least partially form a circuit. The circuit is an open circuit generating a first impedance response when tissue contacts the first electrode and not the second electrode. The circuit is a closed circuit generating a second impedance response when tissue contacts the first and second electrode. The first impedance response has a first impedance value greater than a second impedance value of the second impedance response.
A method of conducting operations for an IPG adapted to provide electrical pulses to tissue of a patient for medical therapy is provided. The IPG provides the medical therapy according to pulse parameter data executed according to an execution path. The method can include identifying a root node repeated within the execution path of a first set of the pulse parameter data, identifying a stimulation pulse pattern repeated in the first set between occurrences of the root node, replacing the repeated pattern with (a) a single instance and a recurrence count or (b) a pointer to a reference pattern to generate a second set of the pulse parameter data, and communicating the second set between the external controller and the IPG and/or storing the second set within a memory of the IPG.
A device and method for assessing rotational stability of an ophthalmic implant. The device includes a holder for receiving within a central portion thereof an ophthalmic implant to be tested. The holder is movable between a first position wherein a first compressive force is exerted on the ophthalmic implant when positioned within the central portion, and a second position wherein a second compressive force is exerted on the ophthalmic implant. The device further includes a drive mechanism coupled to the holder and capable of imparting a reciprocating motion to the holder between the first and second positions.
An implantable lead is described herein that includes a lead body, a fixation helix, and a ring electrode. A proximal end of the lead body is configured to be connected to an implantable medical device. The fixation helix projects beyond a distal end of the lead body to penetrate tissue of a patient. The lead body includes a housing configured to burrow into the tissue of the patient with the fixation helix. The housing is mounted to the ring electrode and extends to the distal end of the lead body. The housing includes a housing helix along an outer surface of the housing, which defines a portion of an exterior surface of the implantable lead. The housing helix has first turns that circumferentially wrap around the housing. The first turns have a common rotational direction as second turns of the fixation helix.
A delivery device including a handle, a sheath defining a lumen and extending distally from the handle, and a hemostasis valve positioned at a proximal end of the handle, the hemostasis valve being located proximal the sheath, the hemostasis valve being rotatable relative to at least one of the sheath and the handle.
The present disclosure relates to catheters comprising a catheter shaft comprising a proximal end and a distal end, and a flexible tip portion comprising an expandable flexible framework comprising a plurality of electrode-carrying arms, wherein each of the plurality of electrode-carrying arm converges with at least one other of the plurality of electrode-carrying arm at a distal apex of the flexible tip portion and wherein each of the plurality of electrode-carrying arms comprises a shape-memory material, and a plurality of electrodes mounted on the electrode-carrying arms. An inflatable balloon is positioned within the expandable flexible framework and is selectively inflatable to adjust the expandable flexible framework from a first non-expanded configuration in which the plurality of electrode-carrying arms form a flexible, substantially planar array, to a second expanded configuration securing a position of the plurality of electrode-carrying arms in an expanded array.
A mitral valvuloplasty balloon catheter includes a handle, a catheter (240+250) extending from the handle, and a balloon (200) operably coupled to a distal end portion of the catheter, the balloon having an inflated condition and a deflated condition. In the inflated condition of the balloon, the balloon includes an atrial end (220), a ventricular end (230) distal to the atrial end, and a waist portion (210) between the atrial end and the ventricular end. The ventricular end (230) has a diameter that is between about 1.4 and about 2.2 times larger than a diameter of the waist portion (210).
A pull wire assembly for a steerable medical device includes a wire lock and a wire. The lock includes a core having a frustoconical outer surface and an annular collar including a frustoconical inner surface complementary to the outer surface of the core. The core is inserted into the collar. The wire is inhibited against distal movement by a compressive force arising within the wire lock when the frustoconical surfaces of the core and collar are forced against each other. The wire may be inserted into the lock between the collar and the core, such that it is pinned therebetween. Alternatively, the wire may be inserted through an interior of the core, such that it is pinned between pieces of the core, such as a plurality of tines or two halves of the core.
A pull wire assembly (30) for a steerable medical device includes a wire lock (32) and a wire (16). The lock includes a core (34) having a frustoconical outer surface (42) and an annular collar (36) including a frustoconical inner surface (44) complementary to the outer surface of the core. The core is inserted into the collar. The wire is inhibited against distal movement by a compressive force arising within the wire lock when the frustoconical surfaces of the core and collar are forced against each other. The wire may be inserted into the lock between the collar and the core, such that it is pinned therebetween. Alternatively, the wire may be inserted through an interior of the core, such that it is pinned between pieces of the core, such as a plurality of tines or two halves of the core.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Dietetic substances, namely infant formula and food for babies adapted for medical use; dietary, nutritional and food supplements for infants for general health and well-being in liquid and powder form; infant formula; food for babies.
The present disclosure includes methods, devices and systems for establishing a connection between a medical device and a remote computing device, receiving an upgrade command at the medical device, storing a current version of persistent data and a current version of executable code in a first storage area of the medical device, transmitting at least the current version of the persistent data to the remote computing device, receiving a second format of the current version of the persistent data and an upgraded version of executable code at the medical device, storing the second format of the current version of the persistent data and the upgraded version of the executable code in a second storage area of the medical device, and executing the upgraded version of the executable code with the second format of the current version of the persistent data.
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
G06F 8/654 - Updates using techniques specially adapted for alterable solid state memories, e.g. for EEPROM or flash memories
G06F 8/71 - Version control Configuration management
G06F 11/10 - Adding special bits or symbols to the coded information, e.g. parity check, casting out nines or elevens
G06F 11/14 - Error detection or correction of the data by redundancy in operation, e.g. by using different operation sequences leading to the same result
Systems, devices, kits, and methods are provided herein in the form of example embodiments that relate to calibration of medical devices. The medical devices can be sensors adapted to sense a biochemical attribute. The embodiments can be used to determine calibration information specific to an individual medical device. The embodiments can determine the calibration information by reference to one or more parameters obtained during manufacturing of the medical device. The embodiments can also determine the calibration information by reference to in vitro testing of the medical devices. The embodiments also apply to systems incorporating those medical devices in their use in the field. Also described are embodiments of modifications to surfaces of sensor substrates, such as through applied radiation and/or the creation of a well, to aid in the placement and/or sizing of a sensor element on the substrate.
Methods and devices herein are provided for managing atrial (A) pacing in connection with premature atrial contracts (PAC). The methods and devices obtain an atrial pace-on-PAC (APAC) interval and cardiac activity (CA) signals. The methods and devices are configured to: i) during a first cardiac beat; following a ventricular paced (VP) or ventricular sensed (VS) event, activate a timer for a post ventricular-atrial refractory period (PVARP) interval; and determine whether a first atrial refractory (AR) event occurs during the PVARP interval; ii) during a second cardiac beat; in response to the detecting that the first AR event occurred, initiate an APAC interval; during the APAC interval for the second cardiac beat, determine whether a second AR event occurs; and update a count of APAC events when the second AR event occurs; and iii) repeat i) and ii) for multiple cardiac beats, to track the count of APAC events.
A61N 1/368 - Heart stimulators controlled by a physiological parameter, e.g. by heart potential comprising more than one electrode co-operating with different heart regions
Method and system for monitoring atrioventricular (AV) conduction and controlling pacing therapy includes determining atrial events for a series of heartbeats over a detection period using a leadless implantable medical device (LIMD) implanted in or on an atrial chamber of a heart. Surrogate AV intervals are determined for at least a portion of the atrial events over the detection period based on a signal indicative of ventricular activity. The surrogate AV intervals are trended over time to generate diagnostic data. The diagnostic data is evaluated against one or more criteria stored in at least one of the LIMD or an external device, and in response to the evaluation satisfying the one or more criteria, an action is initiated to modify an operational mode of at least one LIMD or to generate an alert. The action includes changing the operational mode of at least one LIMD or transmitting the alert to the external device.
A61N 1/368 - Heart stimulators controlled by a physiological parameter, e.g. by heart potential comprising more than one electrode co-operating with different heart regions
A prosthetic heart valve includes a frame and a plurality of prosthetic leaflets mounted within the frame. A first one of the plurality of prosthetic leaflets includes a fixation mechanism. The fixation mechanism may be configured to increase a maximum dimension of one of the plurality of leaflets over a period of time in situ. The fixation mechanism may alternatively or additionally restrict mobility of one or more of the prosthetic leaflets to induce regurgitation when the prosthetic heart valve is implanted. The fixation mechanism may transition over time so that the amount of intentional regurgitation reduces over time, including reducing to substantially zero regurgitation, or any other intentionally designed level of regurgitation. The intentional regurgitation may allow the heart to safely acclimate to new pressure dynamics over time after the implantation.
A system and method for conducting a virtual clinic (VC) session between a patient and a clinician using a VC cloud telehealth system to program an implantable pulse generator (IPG) of a patient to provide a neurostimulation therapy to the patient. One or more VC session models or criteria can be defined that represent clinician and patient interactions during a VC session and a first communication connection can be established between a patient electronic device (PED) and the IPG of the patient. A second communication connection can also be established between a patient electronic device (PED) and the VC cloud telehealth system and a third communication connection can be established between a clinician electronic device (CED) and the VC cloud computing system to connect the patient and clinician for the VC session. Based on input from the clinician electrical stimulation for the neurostimulation therapy can be applied to the patient.
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 80/00 - ICT specially adapted for facilitating communication between medical practitioners or patients, e.g. for collaborative diagnosis, therapy or health monitoring
78.
BATTERY CHARGING SYSTEMS AND METHODS FOR BATTERIES IN IMPLANTABLE MEDICAL DEVICES
An IMD for a patient includes circuitry for providing a medical therapy to the patient and for sensing physiological activity of the patient, a battery for powering the IMD, one or more processors for controlling device operations, and wireless circuitry for communicating with one or more external devices. The IMD predicts a state and/or a capacity of the battery using the processors to generate an output of a computational model. The computational model receives at least one of: an electric characteristic of the battery related to storage, discharge, or charging; an intrinsic characteristic of the battery; a temperature characteristic; a usage characteristic and/or a communication characteristic of communication between the IMD and an external device. The IMD is adapted to communicate a signal indicative of the prediction for one or more of replacing or recharging the battery of the IMD using the wireless communication circuitry.
A method of filtering unwanted motion related artifacts from received sensor-based location data includes receiving unfiltered location data and calculating a plurality of spatio-temporal components associated with the unfiltered location data. The method further includes comparing each spatio-temporal component to the unfiltered location data and updating a weight value based on the comparison of each spatio-temporal component to the unfiltered location data to generate a dynamically updated set of weights. Motion corrected location data is calculated based on the dynamically updated set of weights and the plurality of spatio-temporal components.
Provided are dermal sensors and dermal sensor applicator sets to insert at least a portion of a dermal sensor into a dermal layer of a subject, as well as methods of making and using the same.
A61B 5/1473 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
81.
SYSTEMS, DEVICES, AND METHODS FOR EPISODE DETECTION AND EVALUATION
Systems, devices, and methods are provided that allow detection of episodes in analyte measurement, prompting a patient to self-report possible causes for the episodes. Correlation of possible causes with detected episodes assists patient behavior modification to reduce the occurrence of episodes.
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
G06F 30/20 - Design optimisation, verification or simulation
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
An implantable lead is described that includes a header coupling, a helix shaft, and a fixation helix. The header coupling extends from a proximal end to a distal end thereof, and defines a central lumen from the proximal end to the distal end. The header coupling includes a base section and a distal tube section extending from the base section to the distal end. The helix shaft includes a proximal shank that extends into the central lumen of the header coupling through a distal opening of the distal tube section. The fixation helix is mounted to a distal segment of the helix shaft and is configured to penetrate tissue of a patient. A surface of the header coupling directly engages and is fixedly secured to a surface of the helix shaft, forming a sealed joint that seals the central lumen of the header coupling and prevents fluid from migrating into the central lumen of the lead.
In some examples, a delivery device includes a handle, a sheath defining a lumen and extending distally from the handle, and a hemostasis valve positioned at a proximal end of the handle, the hemostasis valve being located proximal the sheath, the hemostasis valve being rotatable relative to at least one of the sheath and the handle.
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
e.g., e.g., graphical, audible, and/or haptic alerts). The detected changes may relate to changes in the volume of a fluid surrounding the medical device, such as reductions in blood pool volume associated with occlusions, injection of contrast media, or passage of the device into a cardiac vessel from a cardiac chamber. Detected changes may also relate to encountering damaged tissue, such as tissue that includes an ablation lesion.
A61B 5/053 - Measuring electrical impedance or conductance of a portion of the body
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
85.
DEVICES, SYSTEMS AND METHODS OF MEASURING IMPEDANCE OF AN ELECTRODE
A medical device system includes a reference electrode, a drive circuitry configured to provide drive signal, a medical device having at least one electrode located on the medical device, and sense circuitry having a first channel and a second channel. The at least one electrode is connected to receive the drive signal from the drive circuitry. The first channel compares a first voltage measured at the at least one electrode and a reference voltage measured at the reference electrode and the second channel provides a return path for the drive circuitry.
05 - Pharmaceutical, veterinary and sanitary products
29 - Meat, dairy products, prepared or preserved foods
Goods & Services
(1) Dietetic substances, namely infant formula and food for babies adapted for medical use; dietary, nutritional and food supplements for infants for general health and well-being in liquid and powder form; infant formula; food for babies.
(2) Milk and milk products excluding ice cream, ice milk, and frozen yogurt; powdered preparations for making milk beverages; milk powder; milk-based drinks; milk substitutes.
Embodiments described herein include methods and/or systems for updating a medical device. Embodiments include medical devices which are configured for updates in response to various events including connection of a peripheral device to the medical device, a user initiated event, or based on received recommendations.
G01N 33/487 - Physical analysis of biological material of liquid biological material
G06F 11/10 - Adding special bits or symbols to the coded information, e.g. parity check, casting out nines or elevens
G06F 11/14 - Error detection or correction of the data by redundancy in operation, e.g. by using different operation sequences leading to the same result
89.
Tissue Fixation Device With Improved Tissue Securement
A fixation device includes a first proximal element and a first distal element. The first proximal element has a gridded frame disposed between a first end portion and a second end portion and a plurality of frictional elements. The gridded frame has a plurality of axial struts and a plurality of transverse struts intersecting the axial struts to define a plurality of openings. At least some of the frictional elements extend from at least some of the transverse struts. The first distal element is disposed in opposition to the first proximal element and has a cavity disposed between a first end portion and a second end portion thereof. The cavity is configured to receive at least a portion of the gridded frame.
A medical device system includes a reference electrode, a drive circuitry configured to provide drive signal, a medical device having at least one electrode located on the medical device, and sense circuitry having a first channel and a second channel. The at least one electrode is connected to receive the drive signal from the drive circuitry. The first channel compares a first voltage measured at the at least one electrode and a reference voltage measured at the reference electrode and the second channel provides a return path for the drive circuitry.
Disclosed herein are methods and systems for receiving an encoded data packet, one or more activation commands, and a communication identifier, decoding the received data packet, validating the decoded received data packet, and executing one or more routines associated with the respective one or more activation commands.
H04L 1/00 - Arrangements for detecting or preventing errors in the information received
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
G06K 7/10 - Methods or arrangements for sensing record carriers by electromagnetic radiation, e.g. optical sensingMethods or arrangements for sensing record carriers by corpuscular radiation
92.
SYSTEMS, DEVICES, AND METHODS FOR RF DETECTION OF ANALYTE SENSOR MEASUREMENTS
Embodiments that translate a sensor measurement to a frequency characteristic are disclosed. The frequency characteristic can be wirelessly detected by a reader device. The detected frequency characteristic can be used to determine the corresponding sensor measurement. Devices utilizing this approach can be characterized or calibrated to increase accuracy. Systems and methods utilizing the approaches are also described.
G01N 27/02 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance
G01R 23/02 - Arrangements for measuring frequency, e.g. pulse repetition rateArrangements for measuring period of current or voltage
H01Q 1/22 - SupportsMounting means by structural association with other equipment or articles
H01Q 7/00 - Loop antennas with a substantially uniform current distribution around the loop and having a directional radiation pattern in a plane perpendicular to the plane of the loop
93.
IMPLANTABLE MEDICAL DEVICE WITH MULTI-SIDED HEADER ELECTRODE
An implantable medical device includes a header configured to be mounted to an end of a device housing that contains an electronics module therein. The header includes an antenna, a sensing electrode, and a header body that at least partially surrounds the antenna and the sensing electrode. The sensing electrode includes a first body portion, a second body portion, and a bridge portion that mechanically and electrically connects the first and second body portions. The first body portion is at least partially exposed to an external environment along a first side of the header, and the second body portion is at least partially exposed to the external environment along a second side of the header that is different from the first side.
B29C 45/14 - Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mouldApparatus therefor incorporating preformed parts or layers, e.g. injection moulding around inserts or for coating articles
A method of assessing lesion formation associated with pulsed field ablation (PFA) therapy delivered to a selected location by a PFA catheter includes measuring pre-therapy impedance using one or more electrodes located on the catheter and delivering a first PFA application. An intra-therapy/post-therapy impedance is measured using the one or more electrodes located on the catheter and a PFA index (PI) metric is calculated based on a model that combines the measured pre-therapy impedance, the measured intra-therapy/post-therapy impedance, and attributes of the first PFA application delivered, wherein the PI metric is representative of a likelihood that the lesion has reached a selected size.
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A61B 34/10 - Computer-aided planning, simulation or modelling of surgical operations
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
95.
UNSUPERVISED MACHINE LEARNING PARADIGM TO CONTROL CARDIAC AND RESPIRATION RELATED MOTION ARTIFACTS
A method of filtering unwanted motion related artifacts from received sensor-based location data includes receiving unfiltered location data and calculating a plurality of spatio-temporal components associated with the unfiltered location data. The method further includes comparing each spatio-temporal component to the unfiltered location data and updating a weight value based on the comparison of each spatio-temporal component to the unfiltered location data to generate a dynamically updated set of weights. Motion corrected location data is calculated based on the dynamically updated set of weights and the plurality of spatio-temporal components.
A61B 1/04 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor combined with photographic or television appliances
A61B 5/06 - Devices, other than using radiation, for detecting or locating foreign bodies
Embodiments are directed to an implantable medical device comprising therapeutic stimulation circuitry for controlling delivery of a medical therapy to a patient, the therapeutic stimulation circuitry having at least one lead having electrodes for delivering the medical therapy, The implantable medical device further comprises measurement circuitry for determining characteristics of the at least one lead, a processor for controlling the IMD according to executable code, and memory for storing data and executable code, wherein the executable code comprises instructions for causing the processor to receive a plurality of voltage measurements associated with the electrodes, and calculate values for an impedance model of the electrode/tissue interface.
Systems and methods are provided for improving overall vision in patients suffering from a loss of vision in a portion of the retina (e.g., loss of central vision) by providing symmetric or asymmetric optic with aspheric surface which redirects and/or focuses light incident on the eye at oblique angles onto a peripheral retinal location. The intraocular lens can include a redirection element (e.g., a prism, a diffractive element, or an optical component with a decentered GRIN profile) configured to direct incident light along a deflected optical axis and to focus an image at a location on the peripheral retina. Optical properties of the intraocular lens can be configured to improve or reduce peripheral errors at the location on the peripheral retina. One or more surfaces of the intraocular lens can be a toric surface, a higher order aspheric surface, an aspheric Zernike surface or a Biconic Zernike surface to reduce optical errors in an image produced at a peripheral retinal location by light incident at oblique angles.
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 3/028 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient for testing visual acuitySubjective types, i.e. testing apparatus requiring the active assistance of the patient for determination of refraction, e.g. phoropters
A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions
A61B 3/103 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining refraction, e.g. refractometers, skiascopes
A61B 3/107 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining the shape or measuring the curvature of the cornea
A61B 3/14 - Arrangements specially adapted for eye photography
inter aliainter alia, the presence or absence of (i) a trauma mechanism; (ii) a neuroimaging intracranial abnormality; (iii) one or more clinical signs indicative of TBI; (iv) one or more confounding factors; and (v) a level of glial fibrillary acidic protein (GFAP) and/or a level of ubiquitin carboxy-terminal hydrolase L1 (UCH-L1) measured in a sample obtained from the subject. The present disclosure also relates to systems and kits for implementing the methods.
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
100.
INTRAOCULAR IMPLANTS AND METHODS FOR IMPLANTING INTRAOCULAR IMPLANTS
An intraocular implant (150) for implantation in an iris (110) of the eye (100) is disclosed. The intraocular implant (100) may include a tubular member at least partially formed of a shape memory material to enable the tubular member to transition between a first shape and a second shape. The tubular member (100) may have a first retaining element (152), a second retaining element (154), a shaft portion extending between the first and second retaining elements (152, 154), and at least one lumen extending therethrough. The shaft portion of the tubular member may have a length substantially equal to or less than a thickness of the iris (110). The shaft may have a smaller cross- section than the first and second retaining elements (152, 154) when the tubular member is in the second state.
