Abstract

The invention relates to an auto injector with a hydraulic actuator and a separate drug distribution system for subcutaneous injection of a therapeutic drug, wherein the drug distribution system provides a fluid pathway between a drug filled container and a hypodermic needle only when the auto injector is activated.

IPC Classes  ?

• A61M 5/142 - Pressure infusion, e.g. using pumps
• A61M 5/145 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons
• A61M 5/158 - Needles
• A61M 5/20 - Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
• A61M 5/24 - Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or cartridges, e.g. automatic
• A61M 5/31 - Syringes Details
• A61M 5/315 - PistonsPiston-rodsGuiding, blocking or restricting the movement of the rodAppliances on the rod for facilitating dosing
• A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles
• A61M 5/34 - Constructions for connecting the needle

Abstract

An osmotic actuator (110) for a wearable injection device (100) is disclosed, which osmotic actuator comprises a pressure chamber (150) having one or more outlets (152) and containing a draw solution containing dissolved inorganic salt, one or more osmotic membranes (130), and a cavity (140) containing water, and wherein the one or more osmotic membranes (130) form at least a part of one or more internal surfaces of the pressure chamber (150), wherein the water is in contact with at least a part of one or more external surfaces of the one or more osmotic membranes (130), and wherein the dissolved inorganic salt in the draw solution comprises one or more of the following: CaBr2, CaCl2, ZnBr2, ZnCl2, ZnI2 or LiBr. Furthermore, a wearable injection device (100) comprising such an osmotic actuator (110) and the use of such inorganic salts in a draw solution are disclosed.

IPC Classes  ?

• A61M 5/142 - Pressure infusion, e.g. using pumps
• A61M 5/145 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons

Abstract

222222 or LiBr. Furthermore, a wearable injection device (100) comprising such an osmotic actuator (110) and the use of such inorganic salts in a draw solution are disclosed.

IPC Classes  ?

• A61M 5/142 - Pressure infusion, e.g. using pumps
• B01J 4/04 - Feed devicesFeed or outlet control devices using osmotic pressure

Abstract

An osmotic actuator (110) for an injection device (100) is disclosed, which osmotic actuator (110) comprises a pressure chamber (180; 280; 380) having one or more outlets (182; 282; 295; 395) and containing a draw solution, one or more osmotic membranes (130), a cavity (140) containing water, and a dilution-compensating arrangement, wherein the one or more osmotic membranes (130) forms a part of an internal surface area of the pressure chamber (180; 280; 380), wherein the cavity (140) containing water abuts at least part of an external surface of the one or more osmotic membranes (130), and wherein the dilution-compensating arrangement is arranged to compensate for the dilution of the draw solution near the one or more osmotic membranes (130), which occurs when water from the cavity (140) enters the pressure chamber (180; 280; 380) through the one or more osmotic membranes (130). Furthermore, an injection device (100) comprising such an osmotic actuator (110) is disclosed.

IPC Classes  ?

• A61M 5/142 - Pressure infusion, e.g. using pumps
• A61M 5/145 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61M 5/24 - Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or cartridges, e.g. automatic

Abstract

A valve (116, 216) for an injection device (100) is disclosed, which valve is arranged to provide a fluid communication between a drug-filled container (102, 202) and a drug distribution system (101) for distributing a drug to an injection site during use of the device, wherein the valve is substantially cylindrically shaped and is arranged to be at least partly positioned within an outlet portion (123, 223) of the container so that, in an initial configuration, the valve tightly closes the outlet portion, wherein the valve is arranged to be moved through a first distance in a first direction partly into the con- tainer, whereby fluid communication is established through the outlet portion of the container, and wherein the valve is further arranged to be moved through a second distance in a second direction opposite of the first direction.Furthermore, an injection device (100) comprising such a valve (116, 126) is disclosed.

IPC Classes  ?

• A61M 39/22 - Valves or arrangement of valves
• A61J 1/20 - Arrangements for transferring fluids, e.g. from vial to syringe
• A61M 5/31 - Syringes Details
• A61M 5/28 - Syringe ampoules or cartridges, i.e. ampoules or cartridges provided with a needle

Abstract

The invention relates to a wearable injection device (1) for subcutaneous injection of a therapeutic agent, wherein the dose is injected over a specified period of time after the device is activated.

IPC Classes  ?

• A61M 5/142 - Pressure infusion, e.g. using pumps
• A61M 5/145 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons
• A61M 5/24 - Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or cartridges, e.g. automatic