The present invention generally relates to the use of pre-formed bodies of Chemically Bonded Ceramics (CBCs) biomaterial for implantation purposes wherein the bodies are prepared ex vivo allowing process parameters to be optimized for desired long term properties of the resulting CBC biomaterial. More particularly, the pre-formed CBC material bodies of the present invention are sintered. The pre-formed body of CBC material is machined to the desired geometry and then implanted using a CBC cementation paste for fixation of the body to tissue. The invention also relates to a method of preparing pre-formed bodies of CBC biomaterial for implantation purposes, methods of preparing an implant thereof having desired geometry, and a method of implantation of the implant, as well as a kit for use in the method of implantation.
C04B 28/18 - Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing mixtures of the silica-lime type
C04B 35/14 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxides based on silica
C04B 35/48 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxides based on zirconium or hafnium oxides or zirconates or hafnates
The present invention generally relates to the use of pre-formed bodies of Chemically Bonded Ceramics (CBCs) biomaterial for implantation purposes wherein the bodies are prepared ex vivoallowing process parameters to be optimized for desired long term properties of theresulting CBC biomaterial. More particularly, the pre-formed CBC material bodies of the present inven- tion are sintered. The pre-formed body of CBC material is machined to the desired geometry and then implanted using a CBC cementation pastefor fix- ation of the body to tissue. The invention also relates to a method of prepar- ing pre-formed bodies of CBC biomaterial for implantation purposes, meth- ods of preparing an implant thereof having desired geometry, and a method of implantation of the implant, as well as a kit for use in the method of im- plantation.
The present invention generally relates to the use of pre-formed bodies of Chemically Bonded Ceramics (CBCs) biomaterial for implantation purposes wherein the bodies are prepared ex vivo allowing process parameters to be optimized for desired long term properties of the resulting CBC biomaterial. The pre-formed body of CBC material is machined to the desired geometry and the hardened CBC material implant is then implanted using a CBC cementation paste. The invention also relates to a method of preparing pre-formed hardened bodies of CBC biomaterial for implantation purposes, methods of preparing an implant thereof having desired geometry, and a method of implantation of the implant, as well as a kit for use in the method of implantation.
The present invention relates to a calcium aluminate based paste forming a chemically bonded biomaterial on hydration thereof for in vivo anchoring of new implants, or stabilizing of existing implants in situ to an adjacent bone tissue, which paste provides a controlled pH value and temperature as well as initial hardening time. By virtue of the pH value and temperature the paste exhibits antibacterial and/or bacteriostatic properties. The present invention also relates to a method of preparing implants to be implanted wherein the implant is coated with the paste, a method of implanting a coated implant, as well as methods of preventing and treating implant related conditions, such as periimplantitis, and kit for preparing the paste. The invention is especially intended for re-stabilization of dental implants, and implantation into low quality bone tissue.
The present invention relates to chemically bonded ceramic biomaterials, especially a dental material or an implant material. The main binder system forms a chemically bonded ceramic upon hydration thereof, and comprises powdered calcium aluminate and/or calcium silicate, and phase(s) to secure apatite formation at a pH close to neutrality. A second binder system -a cross-linking organic binder system which provides for initial crosslinking of the freshly mixed paste is advantageously added. The invention relates to a powdered composition for preparing the inventive chemically bonded ceramic biomaterial, and a paste from which the biomaterial is formed, as well as a kit comprising the powdered composition and hydration liquid, as well as methods and use of the biomaterial in dental and implant applications with the aim of remineralisation, integration and bone repair.
C04B 28/02 - Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing hydraulic cements other than calcium sulfates
C04B 28/18 - Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing mixtures of the silica-lime type
C04B 28/28 - Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements containing organic polyacids, e.g. polycarboxylate cements
6.
CHEMICALLY BONDED CERAMIC MATERIAL BASED ON TRI CALCIUM OXIDE ALUMINIUM OXIDE (C3A), POWDER AND PASTE FOR FORMING SAME, AND USE THEREOF
The present invention relates to a chemically bonded ceramic material based on 3CaO•Al2O3 (also denoted as C3A) and its use in applications wherein the ambient temperature during hydration is above 25°C. The main binder system forms a chemically bonded ceramic upon hydration thereof and is based onpowdered calcium aluminate, and may optionally contain minor amounts of other phases ofcalcium aluminate and/or calcium silicate. An optimal second binder system is a crosslinking organic binder system which provides for initial crosslinking of the freshly mixed paste forming the biomaterial. The material also comprises inert filler particles. The invention relates to a powdered composition for preparing the inventive chemically bonded ceramic material, and a paste from which the material is formed, as well as a kit comprising the powdered composition and liquid, as well as methods of using the material as a biomaterial in small volume applications, and the use of the general material as a construction material.
The present invention generally relates to chemically bonded ceramic biomaterials, preferably a dental material or an implant material, comprising two binder systems. The main binder system forms a chemically bonded ceramic upon hydration thereof, and comprises powdered calcium aluminate and, optionally, minor amounts of calcium silicate. The second binder system is a cross-linking organic binder system which provides for initial crosslinking of the freshly mixed paste forming the biomaterial. The biomaterial also comprises inert filler particles. The inventive biomaterial is free from reactive glass and thus provides for a simplified two binder systems biomaterial with a reduced number of required reactive components The invention relates to a powdered composition for preparing the inventive chemically bonded ceramic biomaterial, and a paste from which the biomaterial is formed, as well as a kit comprising the powdered composition and hydration liquid, as well as methods and use of the biomaterial in dental and implant applications.
A61L 27/44 - Composite materials, i.e. layered or containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
C04B 24/04 - Carboxylic acidsSalts, anhydrides or esters thereof
C04B 28/00 - Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements
8.
CALCIUM ALUMINATE BASED PASTE FOR STABILIZING DENTAL IMPLANTS AND RESTORING TISSUE ATTACHMENT AFTER SURGERY AND METHODS THEREFOR
The present invention relates to a calcium aluminate based paste forming a chemically bonded biomaterial on hydration thereof for in vivo anchoring of new implants, or stabilizing of existing implants in situ to an adjacent bone tissue, which paste provides a controlled pH value and temperature as well as initial hardening time. By virtue of the pH value and temperature the paste exhibits antibacterial and/or bacteriostatic properties. The present invention also relates to a method of preparing implants to be implanted wherein the implant is coated with the paste, a method of implanting a coated implant, as well as methods of preventing and treating implant related conditions, such as periimplantitis, and a kit for preparing the paste. The invention is especially intended for re-stabilization of dental implants, and implantation into low quality bone tissue.
A dental cement system, including an aqueous hydration liquid and a powdered material that essentially consists of an inorganic cement system, which powdered material has the capacity to form a complex, chemically bonded material with inorganic as well as organic phases with properties suitable for cementation of implant to another implant and/or to tooth or bone tissue.
A dental cement system, comprising an aqueous hydration liquid and a powdered material that essentially consists of an inorganic cement system, which powdered material has the capacity to form a complex, chemically bonded material with inorganic as well as organic phases with properties suitable for cementation of implant to another implant and/or to tooth or bone tissue. The invention relates to the powdered material and the hydration liquid, respectively, as well as the formed ceramic material and a kit comprising the system.
The present invention relates to chemically bonded ceramic precursor material of aluminates and silicates exhibiting a controlled release rate and properties that make the material suitable as a carrier material used in drug delivery. According to the invention, this is accomplished by selecting a micro structure based on pre- reacted phases and/or reacting phases, which contains the drugs. The present invention also relates to a cured ceramic material and a method of manufacturing said cured material. The precursor and the cured ceramic material according to the present invention can suitably be used for different types of drug intake and delivery.
The present invention relates to ceramic precursor material exhibiting injectability and properties that make the material suitable as a carrier material used in drug delivery. According to the invention this is accomplished by selecting a microstructure based on pre-reacted phases and after injection established phases, which contain anti-infective and/or anti-inflammatory drugs. The present invention also relates to a cured ceramic material and a method of manufacturing said cured material. The precursor and the cured ceramic material according to the present invention can suitably be used for filling orthopaedic cavities and other bone voids.
A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
C04B 35/10 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxides based on aluminium oxide
The present invention relates to ceramic precursor material exhibiting injectability and properties that make the material suitable as a carrier material used in drug delivery. According to the invention this is accomplished by selecting a microstructure based on pre-reacted phases and after injection established phases, which contain anti-infective and/or anti-inflammatory drugs. The present invention also relates to a cured ceramic material and a method of manufacturing said cured material. The precursor and the cured ceramic material according to the present invention can suitably be used for filling orthopaedic cavities and other bone voids.
The present invention relates to ceramic precursor compositions and chemically bonded ceramic (CBC) materials, especially Ca-based, and composite biomaterials suitable for orthopaedic and dental applications with improved setting and curing properties resulting in stable close contact between biomaterial and bone tissue. The present invention also relates to a method of manufacturing said cured material, a bioelement and carrier material for drug delivery made by said cured material, a kit comprising the ceramic precursor powder and hydration liquid, as well as the use of said ceramic precursor powder and hydration liquid, or said cured material, for orthopaedic and dental applications.
The present invention relates to ceramic precursor powder compositions and chemically bonded ceramic (CBC) materials, Ca-aluminate and/ or calcium silicate, and a composite biomaterial with prolonged shelf time of the precursor, suitable for orthopaedic applications with improved injectability. The present invention also relates to a method of manufacturing said cured material, bioelements, implants, or drug delivery carrier materials made by said cured material, a kit comprising the ceramic precursor powder and hydration liquid, as well as the use of said ceramic precursor powder and hydration liquid, or said cured material, for orthopaedic and dental applications,
The present invention relates to a ceramic precursor composition for resorbable or partly resorbable high-strength bioelements, wherein the precursor composition comprises 40-70 wt-% of one or more silicate with Ca as the main cation, 40-20 wt- % of a Ca-sulphate, and greater than 0 wt-% to less than 10 wt-% of an acidic soluble Ca-salt, the remainder, if any, comprises additives. The invention also relates to a slurry, a cured material, a medical implant, and a carrier material for drug delivery made from said precursor composition, as well as a method of manufacturing said a cured chemically bonded ceramic material.
The present invention deals with the use of alkaline chemically bonded ceramic systems based on Ca-aluminate as a thrombogenecity reducing coating material. The invention is especially intended for coating of devices used in the human or animal blood system.
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