A colorimetric sensor for detecting an analyte of interest that includes a metal layer disposed upon a substrate, a plurality of nanostructures, and a corresponding plurality of metal deposits spaced apart from the metal layer. The metal layer defines a plurality of holes, each nanostructure includes a first portion disposed within a respective hole, and each metal deposit is disposed upon a second portion of a respective nanostructure. The sensor also includes a molecularly imprinted polymer layer that may cover the metal layer, the nanostructures, and/or the metal deposits. The molecularly imprinted polymer layer defines a cavity shaped to receive the analyte of interest, and the sensor is configured such that, when an analyte contacts the molecularly imprinted polymer layer and becomes disposed within the cavity, an optical property of at least a portion of the sensor changes thereby to cause a detectable color change in and/or from the sensor.
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
2.
CLICKABLE AND CLEAVABLE SENSING SURFACE AND METHOD OF MAKING THE SAME
A sensor, a method of manufacture, and a method of use for detecting an analyte of interest in a fluid sample. The sensor may include a structure that may include a plurality of walls that define a plurality of air gaps in the structure, wherein the plurality of walls may include a plurality of surfaces. The sensor may further include a hydrophobic clickable layer, wherein the hydrophobic clickable layer may be coated on the plurality of walls. The sensor may further include a binding material, wherein the binding material may be coated on the plurality of walls to bind to an analyte of interest. An initial surface energy of at least a portion of the plurality of surfaces of the plurality of walls may change when the analyte of interest binds with the binding material.
A sensor and a method of use may include a structure comprising a plurality of walls that define a plurality of air gaps in the structure, wherein each wall of the plurality of walls may include a plurality of surfaces. The sensor may include a functional layer, wherein the functional layer may be coated on the plurality of walls, wherein the functional layer comprises an extraction component to extract an analyte of interest, at least one amplification initiator to amplify the analyte of interest after extraction, and a material coating the plurality of walls providing an initial surface energy for at least a portion of the plurality of surfaces of the plurality of walls. The initial surface energy of at least the portion of the plurality of surfaces of the plurality of walls provided by the material coating may change when the analyte of interest is present.
A colorimetric sensor for detecting an analyte of interest in a fluid sample includes a photonic structure integrated with a receptor, wherein the photonic structure may be configured such that, when an analyte contacts the receptor within the photonic structure, a refractive property of the photonic structure changes thereby to cause a detectable color change in the photonic structure. The photonic structure may comprise an optical absorber indicator, wherein the receptor may be associated with the optical absorber indicator, such that, when the analyte contacts the receptor, the analyte causes a color change of the optical absorber indicator via a photo-induced electron transfer mechanism. The optical absorber indicator may comprise the photo-induced electron transfer mechanism.
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 31/22 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroupsApparatus specially adapted for such methods using chemical indicators
A colorimetric sensor for detecting an analyte of interest that includes multiple surfaces and a molecularly imprinted polymer defining a cavity shaped to receive an analyte of interest. Each surface defines a void (e.g., a pore or a nanohole) and at least one surface defines a fluid inlet. The sensor is configured such that, when an analyte contacts the molecularly imprinted polymer and becomes disposed within the cavity, a wettability of at least one of the surfaces changes thereby to cause a detectable color change in the sensor. Optionally, the sensor may also include a metal layer at a bottom of each void or nanohole and outside a top of each void or nanohole for use as a plasmon resonance-type sensor.
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 21/41 - RefractivityPhase-affecting properties, e.g. optical path length
A colorimetric sensor for detecting an analyte of interest in a fluid sample includes a lamellar photonic material having alternating layers of a first polymer layer and a second polymer layer. Each first polymer layer can be a molecularly imprinted polymer defining a cavity shaped to receive an analyte of interest. The photonic material is configured such that, when an analyte contacts the photonic material and becomes disposed within a cavity of the molecularly imprinted polymer, a refractive property of the photonic material changes, causing a detectable color change in the sensor.
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 31/22 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroupsApparatus specially adapted for such methods using chemical indicators
B82Y 20/00 - Nanooptics, e.g. quantum optics or photonic crystals
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
7.
Surface plasmon resonance sensor comprising metal coated nanostructures and a molecularly imprinted polymer layer
A colorimetric sensor for detecting an analyte of interest that includes a metal layer disposed upon a substrate, a plurality of nanostructures, and a corresponding plurality of metal deposits spaced apart from the metal layer. The metal layer defines a plurality of holes, each nanostructure includes a first portion disposed within a respective hole, and each metal deposit is disposed upon a second portion of a respective nanostructure. The sensor also includes a molecularly imprinted polymer layer that may cover the metal layer, the nanostructures, and/or the metal deposits. The molecularly imprinted polymer layer defines a cavity shaped to receive the analyte of interest, and the sensor is configured such that, when an analyte contacts the molecularly imprinted polymer layer and becomes disposed within the cavity, an optical property of at least a portion of the sensor changes thereby to cause a detectable color change in and/or from the sensor.
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
B82Y 40/00 - Manufacture or treatment of nanostructures
8.
DEVICES AND METHODS FOR DETECTING A TARGET ANALYTE OF INTEREST
A sensor for detecting an analyte of interest in a fluid sample includes (i) a structure having a plurality of surficial walls that define a plurality of air gaps in the structure and (ii) a binding material. The structure is configured such that both a fluid sample lacking the analyte of interest and a fluid sample containing the analyte of interest are able to penetrate the plurality of air gaps. The binding material, which is present on the plurality of surficial walls, is able to bind the analyte of interest. The sensor is configured such that, when the analyte of interest binds to the binding material, a change in surface energy results within the plurality of surficial walls.
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 33/542 - ImmunoassayBiospecific binding assayMaterials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
9.
DEVICES AND METHODS FOR DETECTING A TARGET ANALYTE OF INTEREST
A sensor for detecting an analyte of interest in a fluid sample includes a receptor and an indicator that is physically spaced from the receptor. The receptor, which may be a filter, includes a binding material that binds an analyte of interest. The receptor may be configured such that, when the analyte of interest binds to the binding material, a change in surface energy results in at least a portion of the receptor. The receptor may further be configured to allow, upon satisfaction of a binding condition, passage of a fluid sample therethrough. The indicator reports the passage of the fluid sample through the receptor.
G01N 33/542 - ImmunoassayBiospecific binding assayMaterials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
B01J 20/00 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
G01N 21/00 - Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
G02B 1/00 - Optical elements characterised by the material of which they are madeOptical coatings for optical elements
G02B 26/00 - Optical devices or arrangements for the control of light using movable or deformable optical elements
10.
DEVICES AND METHODS FOR DETECTING A TARGET ANALYTE OF INTEREST
The invention relates generally to a sensor for detecting an analyte of interest in a sample including a CRISPR system that cleaves a target nucleic acid sequence when the analyte contacts the sensor, thereby producing a detectable signal indicative of the presence of the analyte.
A colorimetric sensor for detecting an analyte of interest that includes multiple surfaces and a molecularly imprinted polymer defining a cavity shaped to receive an analyte of interest. Each surface defines a void (e.g., a pore or a nanohole) and at least one surface defines a fluid inlet. The sensor is configured such that, when an analyte contacts the molecularly imprinted polymer and becomes disposed within the cavity, a wettability of at least one of the surfaces changes thereby to cause a detectable color change in the sensor. Optionally, the sensor may also include a metal layer at a bottom of each void or nanohole and outside a top of each void or nanohole for use as a plasmon resonance-type sensor.
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
A colorimetric sensor for detecting an analyte of interest that includes a metal layer disposed upon a substrate, a plurality of nanostructures, and a corresponding plurality of metal deposits spaced apart from the metal layer. The metal layer defines a plurality of holes, each nanostructure includes a first portion disposed within a respective hole, and each metal deposit is disposed upon a second portion of a respective nanostructure. The sensor also includes a molecularly imprinted polymer layer that may cover the metal layer, the nanostructures, and/or the metal deposits. The molecularly imprinted polymer layer defines a cavity shaped to receive the analyte of interest, and the sensor is configured such that, when an analyte contacts the molecularly imprinted polymer layer and becomes disposed within the cavity, an optical property of at least a portion of the sensor changes thereby to cause a detectable color change in and/or from the sensor.
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
B82Y 40/00 - Manufacture or treatment of nanostructures
13.
Colorimetric chemical sensor with enhanced color sensitivity
A colorimetric sensor for detecting an analyte of interest in a fluid sample includes a lamellar photonic material having alternating layers of a first polymer layer and a second polymer layer. Each first polymer layer can be a molecularly imprinted polymer defining a cavity shaped to receive an analyte of interest. The photonic material is configured such that, when an analyte contacts the photonic material and becomes disposed within a cavity of the molecularly imprinted polymer, a refractive property of the photonic material changes, causing a detectable color change in the sensor.
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 31/22 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroupsApparatus specially adapted for such methods using chemical indicators
B82Y 20/00 - Nanooptics, e.g. quantum optics or photonic crystals
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
14.
COLORIMETRIC SENSORS AND METHODS OF MANUFACTURING THE SAME
A colorimetric sensor for detecting an analyte of interest that includes multiple surfaces and a molecularly imprinted polymer defining a cavity shaped to receive an analyte of interest. Each surface defines a void (e.g., a pore or a nanohole) and at least one surface defines a fluid inlet. The sensor is configured such that, when an analyte contacts the molecularly imprinted polymer and becomes disposed within the cavity, a wettability of at least one of the surfaces changes thereby to cause a detectable color change in the sensor. Optionally, the sensor may also include a metal layer at a bottom of each void or nanohole and outside a top of each void or nanohole for use as a plasmon resonance-type sensor.
G01N 21/45 - RefractivityPhase-affecting properties, e.g. optical path length using interferometric methodsRefractivityPhase-affecting properties, e.g. optical path length using Schlieren methods
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
15.
COLORIMETRIC SENSORS AND METHODS OF MANUFACTURING THE SAME
A colorimetric sensor for detecting an analyte of interest that includes multiple surfaces and a molecularly imprinted polymer defining a cavity shaped to receive an analyte of interest. Each surface defines a void (e.g., a pore or a nanohole) and at least one surface defines a fluid inlet. The sensor is configured such that, when an analyte contacts the molecularly imprinted polymer and becomes disposed within the cavity, a wettability of at least one of the surfaces changes thereby to cause a detectable color change in the sensor. Optionally, the sensor may also include a metal layer at a bottom of each void or nanohole and outside a top of each void or nanohole for use as a plasmon resonance-type sensor.
G02B 1/00 - Optical elements characterised by the material of which they are madeOptical coatings for optical elements
G01N 21/45 - RefractivityPhase-affecting properties, e.g. optical path length using interferometric methodsRefractivityPhase-affecting properties, e.g. optical path length using Schlieren methods
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
A colorimetric sensor for detecting an analyte of interest that includes a metal layer disposed upon a substrate, a plurality of nanostructures, and a corresponding plurality of metal deposits spaced apart from the metal layer. The metal layer defines a plurality of holes, each nanostructure includes a first portion disposed within a respective hole, and each metal deposit is disposed upon a second portion of a respective nanostructure. The sensor also includes a molecularly imprinted polymer layer that may cover the metal layer, the nanostructures, and/or the metal deposits. The molecularly imprinted polymer layer defines a cavity shaped to receive the analyte of interest, and the sensor is configured such that, when an analyte contacts the molecularly imprinted polymer layer and becomes disposed within the cavity, an optical property of at least a portion of the sensor changes thereby to cause a detectable color change in and/or from the sensor.
A colorimetric sensor for detecting an analyte of interest that includes a metal layer disposed upon a substrate, a plurality of nanostructures, and a corresponding plurality of metal deposits spaced apart from the metal layer. The metal layer defines a plurality of holes, each nanostructure includes a first portion disposed within a respective hole, and each metal deposit is disposed upon a second portion of a respective nanostructure. The sensor also includes a molecularly imprinted polymer layer that may cover the metal layer, the nanostructures, and/or the metal deposits. The molecularly imprinted polymer layer defines a cavity shaped to receive the analyte of interest, and the sensor is configured such that, when an analyte contacts the molecularly imprinted polymer layer and becomes disposed within the cavity, an optical property of at least a portion of the sensor changes thereby to cause a detectable color change in and/or from the sensor.
A colorimetric sensor for detecting an analyte of interest in a fluid sample includes a lamellar photonic material having alternating layers of a first polymer layer and a second 5 polymer layer. Each first polymer layer can be a molecularly imprinted polymer defining a cavity shaped to receive an analyte of interest. The photonic material is configured such that, when an analyte contacts the photonic material and becomes disposed within a cavity of the molecularly imprinted polymer, a refractive property of the photonic material changes, causing a detectable color change in the sensor.
G08B 21/00 - Alarms responsive to a single specified undesired or abnormal condition and not otherwise provided for
G01N 31/22 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroupsApparatus specially adapted for such methods using chemical indicators
An apparatus is configured to detect a beverage that is contaminated with a substance. The apparatus may include a testing material, wherein the testing material may comprise a cavity having a complementary shape to a molecule associated with the substance. The apparatus may include a taste substance filling the cavity, wherein the taste substance filling the cavity may bleed out into the beverage when the molecule associated with the substance in the beverage replaces the taste substance filling the cavity, wherein a taste of the beverage may change when the taste substance bleeds out into the beverage as an indicator that the substance is present in the beverage.
G01N 31/22 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroupsApparatus specially adapted for such methods using chemical indicators
B65D 77/24 - Inserts or accessories added or incorporated during filling of containers
A47G 19/22 - Drinking vessels or saucers used for table service
A system and method for a beverage container configured to test for a contaminated beverage in the beverage container comprises a base of the beverage container, an upper portion of the beverage container, and a sidewall with an inner surface and an outer surface that extends from the base to the upper portion, and a testing material. A portion of the beverage container is the testing material configured to visibly react when the portion of the beverage container is contacted with the contaminated beverage.
G01N 31/22 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroupsApparatus specially adapted for such methods using chemical indicators
21.
System and method for detection of a contaminated beverage
An apparatus may be configured to test a beverage, the apparatus may include but is not limited to, a food container, wherein the food container includes a material. An indicator may be combined with at least a portion of the material of the food container, wherein the indicator may be associated with a brand profile that may identify a brand of the food, wherein the indicator may visibly react when the indicator is contacted with the food to show whether the food is identified as the brand of the food, and wherein the visible reaction may be shown on at least the portion of the material of the food container via the indicator combined with at least the portion of the material of the food container.
A47G 19/22 - Drinking vessels or saucers used for table service
G01N 31/22 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroupsApparatus specially adapted for such methods using chemical indicators
G01N 33/94 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving narcotics
An apparatus may be configured to test a beverage, the apparatus may include but is not limited to, a beverage container that may be configured to hold a beverage, wherein the beverage container may include a material. An indicator may be chemically bonded to at least a portion of the material of the beverage container, wherein at least the portion of the material of the beverage container may include the indicator, wherein the indicator may be associated with at least part of a brand profile to identify a brand of the beverage, wherein the indicator may visibly react when the indicator is contacted with the beverage to show whether the beverage may be identified as the brand of the beverage, and wherein the visible reaction may be shown on at least the portion of the material of the beverage container via the indicator chemically bonded to at least the portion of the material of the beverage container.
G01N 31/22 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroupsApparatus specially adapted for such methods using chemical indicators
23.
System and method for detection of a contaminated beverage
A system and method for a beverage container configured to test for a contaminated beverage in the beverage container comprises a base of the beverage container, an upper portion of the beverage container, and a sidewall with an inner surface and an outer surface that extends from the base to the upper portion, and a testing material. A portion of the beverage container is the testing material configured to visibly react when the portion of the beverage container is contacted with the contaminated beverage.
G01N 31/22 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroupsApparatus specially adapted for such methods using chemical indicators
24.
System and method for detection of a contaminated beverage
A system and method for a beverage container configured to test for a contaminated beverage in the beverage container comprises a base of the beverage container, an upper portion of the beverage container, and a sidewall with an inner surface and an outer surface that extends from the base to the upper portion, and a testing material. A portion of the beverage container is the testing material configured to visibly react when the portion of the beverage container is contacted with the contaminated beverage.
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 21/75 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
G01N 31/22 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroupsApparatus specially adapted for such methods using chemical indicators
A system and method for a beverage container configured to test for a contaminated beverage in the beverage container comprises a base of the beverage container, an upper portion of the beverage container, and a sidewall with an inner surface and an outer surface that extends from the base to the upper portion, and a testing material. A portion of the beverage container is the testing material configured to visibly react when the portion of the beverage container is contacted with the contaminated beverage.
G01N 21/75 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
G01N 31/22 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroupsApparatus specially adapted for such methods using chemical indicators
patents
