Abstract

The present invention relates to a composition for inhibiting VEGF-induced angiogenesis, the composition comprising a CCL8-binding peptide. The composition according to the present invention can contribute to preventing cancer progression and metastasis by inhibiting cancer cell proliferation and inhibiting cancer cell migration and invasion. On the basis thereof, the present invention can be effectively used in various medicines and foods for preventing, alleviating, or treating cancer, as well as in the feed industry.

IPC Classes  ?

• A61K 38/10 - Peptides having 12 to 20 amino acids
• A61P 35/00 - Antineoplastic agents
• A23L 33/18 - PeptidesProtein hydrolysates
• A23K 20/147 - Polymeric derivatives, e.g. peptides or proteins

Abstract

The present invention relates to a composition for the prevention, alleviation, or treatment of inflammatory diseases, comprising 1-alkyl-5-arylidene-2-selenoxoimidazolidin-4-one and derivatives thereof. Specifically, the novel compounds of the present invention, 1-alkyl-5-arylidene-2-selenoxoimidazolidin-4-one and derivatives thereof, can be used as excellent pharmaceutical compositions and food compositions for the prevention, alleviation, or treatment of inflammatory diseases.

IPC Classes  ?

• A61K 31/4152 - 1,2-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. antipyrine, phenylbutazone, sulfinpyrazone
• A61K 31/4155 - 1,2-Diazoles not condensed and containing further heterocyclic rings
• A61K 31/4439 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
• A61K 31/4525 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
• A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
• A61K 31/5377 - 1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
• A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]

Abstract

The present invention relates to 1-alkyl-5-arylidene-2-selenoxoimidazolidine-4-ons and derivatives thereof, a method for producing the same, and a composition for prevention, improvement or treatment of neurodegenerative disease containing the same. Specifically, 1-alkyl-5-arylidene-2-selenoxoimidazolidine-4-ons and derivatives thereof, which are novel compounds of the present invention, can be used as an excellent composition for prevention, improvement or treatment of neurodegenerative disease.

IPC Classes  ?

• C07D 403/10 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a carbon chain containing aromatic rings
• C07D 233/96 - Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
• C07D 401/06 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

The present invention relates to a composition comprising 1-alkyl-5-arylidene-2-selenoxoimidazolidin-4-one and a derivative thereof for prevention, alleviation, or treatment of inflammatory diseases. Specifically, 1-alkyl-5-arylidene-2-selenoxoimidazolidin-4-one, which is the novel compound of the present invention, and a derivative thereof can be used in an excellent pharmaceutical composition and food composition for prevention, alleviation, or treatment of inflammatory diseases.

IPC Classes  ?

• A61K 31/4166 - 1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
• A61K 31/454 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
• A61K 31/4178 - 1,3-Diazoles not condensed and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
• A61K 31/4439 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
• A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
• A61K 31/5377 - 1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
• A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]

Abstract

The present invention relates to 1-alkyl-5-arylidene-2-selenoxoimidazolidine-4-on and a derivative thereof, a preparation method therefor, and a composition comprising same for preventing, alleviating or treating neurodegenerative diseases. Specifically, 1-alkyl-5-arylidene-2-selenoxoimidazolidine-4-on and a derivative thereof, of the present invention, can be used as an excellent composition for preventing, alleviating or treating neurodegenerative diseases.

IPC Classes  ?

• C07D 233/96 - Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
• C07D 401/06 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
• C07D 403/06 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
• C07D 401/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
• C07D 403/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing three or more hetero rings
• A61K 31/4166 - 1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

The present invention relates to an antibacterial composition which shows strong antibacterial activity toward food poisoning bacteria by containing essential oil extracted from Chrysanthemum morifolium flower as an effective component, and can be used as a food supplement, or a medicine or a supplement for treating food poisoning since an antibiotic action is maintained for a long time. An antibacterial composition of the present invention contains essential oil, which is an extract of Chrysanthemum morifolium flower, as an effective component.

IPC Classes  ?

• A01N 65/12 - Asteraceae or Compositae [Aster or Sunflower family], e.g. daisy, pyrethrum, artichoke, lettuce, sunflower, wormwood or tarragon
• A01P 1/00 - DisinfectantsAntimicrobial compounds or mixtures thereof

Abstract

The present invention relates to a method for enhancing storage stability of traditional soybean paste, and more specifically, to a method for enhancing storage stability of traditional soybean paste by treating an inner surface of a cap of a container that stores the soybean paste with an essential oil, or by directly mixing the essential oil with the soybean paste. By storing the soybean paste with essential oil treated on the inner surface of the cap of the container, or by treating the soybean paste by directly mixing in the essential oil, proliferation of common bacteria can be suppressed, and the treatment can have a positive effect in suppressing discoloration of the soybean paste. Therefore, the method of the present invention can be useful for enhancing the storage stability of traditional soybean pastes.

IPC Classes  ?

• A23L 3/3472 - Compounds of undetermined constitution obtained from animals or plants
• A23L 1/202 - Malt products; Fermented malt products (A23L 1/22 takes precedence;malt products of cereals A23L 1/185)

Abstract

The present invention relates to a composition containing citrus rind extract for preventing discoloration of fruits and vegetables. The citrus rind extract of the present invention has excellent effect on inhibiting polyphenol oxidase activity, thereby effectively preventing discoloration of fruits and vegetables.

IPC Classes  ?

• A23B 7/153 - Preserving or ripening with chemicals not covered by group or in the form of liquids or solids
• A23L 3/3454 - Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
• A23L 1/272 - Retaining or modifying natural colour by use of additives, e.g. optical brighteners (A23L 1/275 takes precedence);;

Abstract

The present invention relates to a composition containing Chrysanthemum indicum L. extract for preventing discoloration of fruits and vegetables. The Crysanthemum indicum L. extract of the present invention has excellent effect on inhibiting polyphenol oxidase activity, thereby effectively preventing discoloration of fruits and vegetables.

IPC Classes  ?

• A23B 7/153 - Preserving or ripening with chemicals not covered by group or in the form of liquids or solids
• A23L 3/3454 - Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
• A23L 1/272 - Retaining or modifying natural colour by use of additives, e.g. optical brighteners (A23L 1/275 takes precedence);;