DUKSUNG WOMEN'S UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (Republic of Korea)
Inventor
Kang, Kye Tae
Moon, Aree
Cho, Hyo Sun
Jung, Joo Hee
Song, Kyoung
Kim, Eun Sook
Abstract
The present invention relates to a composition for inhibiting VEGF-induced angiogenesis, the composition comprising a CCL8-binding peptide. The composition according to the present invention can contribute to preventing cancer progression and metastasis by inhibiting cancer cell proliferation and inhibiting cancer cell migration and invasion. On the basis thereof, the present invention can be effectively used in various medicines and foods for preventing, alleviating, or treating cancer, as well as in the feed industry.
A23K 20/147 - Polymeric derivatives, e.g. peptides or proteins
2.
PHARMACEUTICAL AND FOOD COMPOSITIONS FOR THE PREVENTION, ALLEVIATION, OR TREATMENT OF INFLAMMATORY DISEASES COMPRISING 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDIN-4-ONE AND ITS DERIVATIVES
DUKSUNG WOMEN'S UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (Republic of Korea)
INDUSTRY ACADEMIC COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY (Republic of Korea)
Inventor
Lee, Sang Hyup
Choi, Dong Young
Cho, Hyun Sung
Kim, Cho Rong
Lim, Yoo Jin
Kim, Ye Eun
Jeong, Yu Ra
Abstract
The present invention relates to a composition for the prevention, alleviation, or treatment of inflammatory diseases, comprising 1-alkyl-5-arylidene-2-selenoxoimidazolidin-4-one and derivatives thereof. Specifically, the novel compounds of the present invention, 1-alkyl-5-arylidene-2-selenoxoimidazolidin-4-one and derivatives thereof, can be used as excellent pharmaceutical compositions and food compositions for the prevention, alleviation, or treatment of inflammatory diseases.
A61K 31/4152 - 1,2-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. antipyrine, phenylbutazone, sulfinpyrazone
A61K 31/4155 - 1,2-Diazoles not condensed and containing further heterocyclic rings
A61K 31/4439 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A61K 31/4525 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
A61K 31/5377 - 1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
3.
1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDINE-4-ON AND DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, AND COMPOSITION COMPRISING SAME FOR PREVENTING, ALLEVIATING OR TREATING NEURODEGENERATIVE DISEASES
DUKSUNG WOMEN'S UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (Republic of Korea)
KNU-INDUSTRY COOPERATION FOUNDATION (Republic of Korea)
INDUSTRY ACADEMIC COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY (Republic of Korea)
EWHA UNIVERSITY - INDUSTRY COLLABORATION FOUNDATION (Republic of Korea)
Inventor
Lee, Sang Hyup
Choi, Dong Young
Lee, Jungkwan
Ahn, Sung Hoon
Choi, Sun
Cho, Hyun Sung
Kim, Cho Rong
Lim, Yoo Jin
Kim, Ye Eun
Lee, Yoonji
Abstract
The present invention relates to 1-alkyl-5-arylidene-2-selenoxoimidazolidine-4-ons and derivatives thereof, a method for producing the same, and a composition for prevention, improvement or treatment of neurodegenerative disease containing the same. Specifically, 1-alkyl-5-arylidene-2-selenoxoimidazolidine-4-ons and derivatives thereof, which are novel compounds of the present invention, can be used as an excellent composition for prevention, improvement or treatment of neurodegenerative disease.
C07D 403/10 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a carbon chain containing aromatic rings
C07D 233/96 - Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
C07D 401/06 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
4.
PHARMACEUTICAL COMPOSITION AND FOOD COMPOSITION COMPRISING 1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDIN-4-ONE AND DERIVATIVE THEREOF FOR PREVENTION, ALLEVIATION, OR TREATMENT OF INFLAMMATORY DISEASE
DUKSUNG WOMEN'S UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (Republic of Korea)
INDUSTRY ACADEMIC COOPERATION FOUNDATION OF YEUNGNAM UNIVERSITY (Republic of Korea)
Inventor
Lee, Sang Hyup
Choi, Dong Young
Cho, Hyun Sung
Kim, Cho Rong
Lim, Yoo Jin
Kim, Ye Eun
Jeong, Yu Ra
Abstract
The present invention relates to a composition comprising 1-alkyl-5-arylidene-2-selenoxoimidazolidin-4-one and a derivative thereof for prevention, alleviation, or treatment of inflammatory diseases. Specifically, 1-alkyl-5-arylidene-2-selenoxoimidazolidin-4-one, which is the novel compound of the present invention, and a derivative thereof can be used in an excellent pharmaceutical composition and food composition for prevention, alleviation, or treatment of inflammatory diseases.
A61K 31/4166 - 1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
A61K 31/454 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
A61K 31/4178 - 1,3-Diazoles not condensed and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
A61K 31/4439 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
A61K 31/5377 - 1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
5.
1-ALKYL-5-ARYLIDENE-2-SELENOXOIMIDAZOLIDINE-4-ON AND DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, AND COMPOSITION COMPRISING SAME FOR PREVENTING, ALLEVIATING OR TREATING NEURODEGENERATIVE DISEASES
DUKSUNG WOMEN'S UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (Republic of Korea)
Inventor
Lee, Sang Hyup
Choi, Dong Young
Lee, Jungkwan
Ahn, Sung Hoon
Choi, Sun
Cho, Hyun Sung
Kim, Cho Rong
Lim, Yoo Jin
Kim, Ye Eun
Lee, Yoonji
Abstract
The present invention relates to 1-alkyl-5-arylidene-2-selenoxoimidazolidine-4-on and a derivative thereof, a preparation method therefor, and a composition comprising same for preventing, alleviating or treating neurodegenerative diseases. Specifically, 1-alkyl-5-arylidene-2-selenoxoimidazolidine-4-on and a derivative thereof, of the present invention, can be used as an excellent composition for preventing, alleviating or treating neurodegenerative diseases.
C07D 233/96 - Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
C07D 401/06 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
C07D 403/06 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
C07D 401/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
C07D 403/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing three or more hetero rings
A61K 31/4166 - 1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
6.
ANTIBACTERIAL COMPOSITION EXTRACTED FROM CHRYSANTHEMUM MORIFOLIUM FLOWER
DUKSUNG WOMEN'S UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (Republic of Korea)
Inventor
Kim, Gun Hee
Lee, Je Hyuk
Jang, Mi Ran
Abstract
The present invention relates to an antibacterial composition which shows strong antibacterial activity toward food poisoning bacteria by containing essential oil extracted from Chrysanthemum morifolium flower as an effective component, and can be used as a food supplement, or a medicine or a supplement for treating food poisoning since an antibiotic action is maintained for a long time. An antibacterial composition of the present invention contains essential oil, which is an extract of Chrysanthemum morifolium flower, as an effective component.
DUKSUNG WOMEN'S UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (Republic of Korea)
Inventor
Kim, Gun Hee
Chung, Mi Sook
Abstract
The present invention relates to a method for enhancing storage stability of traditional soybean paste, and more specifically, to a method for enhancing storage stability of traditional soybean paste by treating an inner surface of a cap of a container that stores the soybean paste with an essential oil, or by directly mixing the essential oil with the soybean paste. By storing the soybean paste with essential oil treated on the inner surface of the cap of the container, or by treating the soybean paste by directly mixing in the essential oil, proliferation of common bacteria can be suppressed, and the treatment can have a positive effect in suppressing discoloration of the soybean paste. Therefore, the method of the present invention can be useful for enhancing the storage stability of traditional soybean pastes.
DUKSUNG WOMEN'S UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (Republic of Korea)
Inventor
Kim, Gun Hee
Chang, Min Sun
Abstract
The present invention relates to a composition containing citrus rind extract for preventing discoloration of fruits and vegetables. The citrus rind extract of the present invention has excellent effect on inhibiting polyphenol oxidase activity, thereby effectively preventing discoloration of fruits and vegetables.
A23B 7/153 - Preserving or ripening with chemicals not covered by group or in the form of liquids or solids
A23L 3/3454 - Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
A23L 1/272 - Retaining or modifying natural colour by use of additives, e.g. optical brighteners (A23L 1/275 takes precedence);;
9.
COMPOSITION CONTAINING CHRYSANTHEMUM INDICUM L. EXTRACT FOR PREVENTING DISCOLORATION
DUKSUNG WOMEN'S UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (Republic of Korea)
Inventor
Kim, Gun Hee
Chang, Min Sun
Abstract
The present invention relates to a composition containing Chrysanthemum indicum L. extract for preventing discoloration of fruits and vegetables. The Crysanthemum indicum L. extract of the present invention has excellent effect on inhibiting polyphenol oxidase activity, thereby effectively preventing discoloration of fruits and vegetables.
A23B 7/153 - Preserving or ripening with chemicals not covered by group or in the form of liquids or solids
A23L 3/3454 - Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
A23L 1/272 - Retaining or modifying natural colour by use of additives, e.g. optical brighteners (A23L 1/275 takes precedence);;