The invention provides compounds having the general formula (I), wherein R1, R2, X, and Y are as described herein, compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds.
C07D 205/12 - Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
C07D 207/06 - Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with radicals, containing only hydrogen and carbon atoms, attached to ring carbon atoms
C07D 207/20 - Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
National Chung Hsing University (Taiwan, Province of China)
Inventor
Zierer, Wolfgang
Sonnewald, Uwe
Lamm, Christian
Gruissem, Wilhelm
Anjanappa, Ravi Bodampalli
Chang, Shu-Heng
Abstract
The present invention provides novel DNA molecules and constructs, including their nucleotide sequences, useful for modulating gene expression in plants and plant cells. The invention also provides transgenic plants, plant cells, plant parts, seeds, and commodity products comprising the DNA molecules operably linked to heterologous transcribable polynucleotides, along with methods of their use.
NATIONAL CHUNG HSING UNIVERSITY (Taiwan, Province of China)
Inventor
Zierer, Wolfgang
Sonnewald, Uwe
Lamm, Christian
Gruissem, Wilhelm
Anjanappa, Ravi Bodampalli
Chang, Shu-Heng
Abstract
The present invention provides novel DNA molecules and constructs, including their nucleotide sequences, useful for modulating gene expression in plants and plant cells. The invention also provides transgenic plants, plant cells, plant parts, seeds, and commodity products comprising the DNA molecules operably linked to heterologous transcribable polynucleotides, along with methods of their use.
A rechargeable battery having a dilute halogenated cationic electrolyte additive that has decomposition potentials higher than those of solvent and anions. These additives utilizes electrostatic attraction between halogenated cations and a negatively charged anode, creating a halogen-rich interphase layer at the electrode surfaces. A robust, halogen-rich interfacial layer is formed at the anode, enabling stable cycling of high-capacity anode including, but not limited to, Li-metal. For Li-metal anodes a dendrite-free deposition of dense Li-metal with very high plating/stripping efficiency is achieved. A millimolar addition of halogenated cations improves the oxidation stability of ether-based electrolytes and suppresses the corrosion of the aluminum current collectors, allowing the cycling of battery cells that use high-voltage cathodes.
A system for frequency conversion of laser pump radiation includes an optical element for frequency conversion of lasers or laser beams with power scalability. The element has a nonlinear birefringent, thin plate crystal. A pump beam generates frequency-shifted radiation. Phase or quasi-phase matching conditions are in the crystal between beams. Frontside and backside of the crystal have high-reflective and partially-reflective coatings, obtaining intensity enhancement of the pump and frequency-converted radiation, and maintaining relative phase delay between beams, maximizing conversion efficiency. The crystal contacts a heat sink through the high-reflective coating, minimizing temperature inhomogeneity in the crystal. Intrinsic longitudinal heat flow provides power scalability. The element, used intra-cavity, acts as a wavelength-selective component forcing laser operation on resonance of the element, maximizing frequency conversion. The wavelength selectivity allows single-frequency operation of high-power lasers with intra-cavity frequency conversion.
A binding moiety (B) for Carbonic Anhydrase IX (CAIX), the binding moiety comprising:
A binding moiety (B) for Carbonic Anhydrase IX (CAIX), the binding moiety comprising:
A binding moiety (B) for Carbonic Anhydrase IX (CAIX), the binding moiety comprising:
The binding moiety is univalent, bivalent, or multivalent. A targeted therapeutic agent may comprise the binding moiety. The invention also includes a method for treating a disease expressing elevated levels of CAIX by administering the targeted therapeutic agent.
A61K 47/54 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
A61K 31/535 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and at least one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
C07B 59/00 - Introduction of isotopes of elements into organic compounds
C07K 5/083 - Tripeptides the side chain of the first amino acid being acyclic, e.g. Gly, Ala
A61K 47/65 - Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
A61K 47/55 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
Disclosed herein are contiguous DNA sequences encoding highly compact multi-input genetic logic gates for precise in vivo cell targeting, and methods of treating disease using a combination of in vivo delivery and such contiguous DNA sequences.
The invention relates to an extracorporeal circuit support with a main liquid pump (5), the inlet of which can be connected to the blood circuit of a patient (7) via at least one first liquid line and the outlet of which can be connected to the blood circuit via at least one second liquid line, an oxygenator (6) for enriching the blood being conducted in the at least one second liquid line with oxygen, and a pump drive which drives the main liquid pump (5). The extracorporeal circuit support according to the invention is characterized in that in addition to the main blood pump or main liquid pump (5) and the oxygenator (6), the pump drive is designed to be MR-conditional, i.e., MR-compliant under specific conditions, and is designed in the form of a gas expansion motor (3). The extracorporeal circuit support according to the invention can be used as a heart-lung machine or as an ECMO device.
A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
A61M 60/109 - Extracorporeal pumps, i.e. the blood being pumped outside the patient’s body incorporated within extracorporeal blood circuits or systems
Described herein are methods of producing glycosylated proteins in vitro and in vivo. The methods include using host cells to produce glycosylated proteins. Also described herein are glycosylated proteins produced using such methods and uses thereof.
C07K 14/285 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
A diffractometric sensor (1), comprises:- a substrate (3);- two interdigitated affinity gratings (2), a first affinity grating (20) comprising first unit cells (200) with affinity elements (201) and a second affinity grating (21) comprising second unit cells (210) with affinity elements (211),wherein the first unit cells (200) and second unit cells (210) are configured and arranged such that coherent light of a predetermined wavelength generated at a predetermined beam generation location (40) and diffracted by target molecules (204, 214)) bound to the affinity elements (201, 211) constructively interferes at a predetermined detection location (50) with an inverse phase, and wherein the first and second affinity gratings (20, 21) are balanced to generate a bias signal at the predetermined detection location (50) that corresponds to a difference (∆m) in the scattering mass of the first and second affinity gratings (20, 21) which is in the range of 0.001 pg/mm2to 30000 pg/mm2.
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
It is provided a robotic foot (1), configured to rest on a support surface and comprising: an attachment (2) to an external object; a chain (31) defining a contact area (1a) with the support surface; a first arm (41) constrained to the chain (31) at a first end of the chain (31) and hinged to the attachment (2); a second arm constrained (42) to the chain (31) at a second end of the chain (31) and hinged to the attachment (2); and elastic means (46) adapted to reciprocally spread the arms (41, 42) keeping the chain (31) taut and opposing a deformation of the chain (31) when in contact with the irregular support surface.
B62D 57/032 - Vehicles characterised by having other propulsion or other ground-engaging means than wheels or endless track, alone or in addition to wheels or endless track with ground-engaging propulsion means, e.g. walking members with alternately or sequentially lifted supporting base and legVehicles characterised by having other propulsion or other ground-engaging means than wheels or endless track, alone or in addition to wheels or endless track with ground-engaging propulsion means, e.g. walking members with alternately or sequentially lifted feet or skid
It is provided a robot (10) comprising a limb (11) comprising a robotic foot (1) defining a contact area (1a) to a resting surface and an anchoring body (111) of the robotic foot (1); a motor (12) for moving the limb (11) and a control unit (13) for the motor (12); the robotic foot (1) comprises an attachment (2) to the anchoring body (11); a contact member (3) defining the contact area (1a); a joint block (4) of the contact member (3) to the attachment (2) comprising a first hinge (43) between the contact member (3) and the attachment (2), a second hinge (44) between the contact member (3) and contact (3) and attachment (2); an additional hinge (45) between attachment (2) and joint block (4); at least one sensor (5, 6) for measuring a rotation; an additional sensor (7a, 7b) for measuring the additional rotation; and the control unit (13) is configured to drive the motor (12) according to the measurement of said rotations.
B62D 57/032 - Vehicles characterised by having other propulsion or other ground-engaging means than wheels or endless track, alone or in addition to wheels or endless track with ground-engaging propulsion means, e.g. walking members with alternately or sequentially lifted supporting base and legVehicles characterised by having other propulsion or other ground-engaging means than wheels or endless track, alone or in addition to wheels or endless track with ground-engaging propulsion means, e.g. walking members with alternately or sequentially lifted feet or skid
14.
FOAMED, DOUGH-BASED FOOD AND APPARATUS AND METHOD FOR PRODUCTION THEREOF AND USE OF THE APPARATUS
A dough-based food product, an apparatus and method for production thereof. A food product matrix to be foamed includes a proportion of a starch-containing raw material and a proportion of water. Gas that has been dissolved or is to be dissolved is introduced into the food product matrix to be foamed. The gas is dissolved under pressure in the food product matrix to be foamed. Gas bubbles are formed by expansion and increasing the volume with a resulting reduction in density of the dough as a result of bubble growth for formation of a foamed food product matrix of the food product to be produced. The foam is then stabilized. Gas is introduced into and dissolved in the aqueous component of the food product matrix to be foamed in a subcritical state below the critical point and at a pressure of 10 bar≤p
A23P 30/34 - Puffing or expanding by pressure release, e.g. explosion puffingPuffing or expanding by vacuum treatment by extrusion-expansion
A23L 7/178 - Preparation of puffed cereals from wholegrain or grain pieces without preparation of meal or dough by pressure release with or without heating
A21C 1/00 - Mixing or kneading machines for the preparation of dough
A21C 14/00 - Machines or equipment for making or processing dough, not provided for in other groups of this subclass
15.
A METHOD TO TREAT DISEASE USING A NUCLEIC ACID VECTOR ENCODING A HIGHLY COMPACT MULTI-INPUT LOGIC GATE
Disclosed herein are contiguous DNA sequences encoding highly compact multi-input genetic logic gates for precise in vivo cell targeting, and methods of treating disease using a combination of in vivo delivery and such contiguous DNA sequences.
Disclosed herein are contiguous DNA sequences encoding highly compact multi-input genetic logic gates for precise in vivo cell targeting, and methods of treating disease using a combination of in vivo delivery and such contiguous DNA sequences.
The present invention relates to novel coatings and its uses, as well as processes of making such coatings. The coatings are characterized by their chemical composition and architecture; they are antimicrobial, tissue regenerative and tissue bonding, making them useful as a coating of an implant. Manufacturing processes for such coating combines flame spray pyrolysis and direct coating of a substrate; the process uses inexpensive starting materials and is scalable.
A library is provided having a plurality of recombinant derivatives of the SH3 domain of the Fyn kinase of SEQ ID NO: 1, where one or more of the derivatives have a specific binding affinity to a protein or peptide that is not a natural SH3 binding ligand. Substantially each of the derivatives of the SH3 domain of the Fyn kinase of SEQ ID NO: 1 has an amino acid sequence with at least 80% sequence identity to the amino acid sequence of SEQ ID NO: 1, and at least 90% identity to the amino acid of SEQ ID NO: 1 outside the src and RT loops. Additionally, the amino acid sequence has at least one amino acid in or positioned up to two amino acids adjacent to the RT loop or the src loop of SEQ ID NO: 1 which is substituted, deleted or added.
G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
C12Q 1/48 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving transferase
20.
ON-BOARD VISUAL DETERMINATION OF KINEMATIC MEASUREMENT VARIABLES OF A RAIL VEHICLE
The invention relates to a method for determining a kinematic variable (v, P, a) of a rail vehicle (31). In the method, image data (BD) comprising a sequence of images of the surroundings of the rail vehicle (31) is captured using an on-board image-capturing unit (32), and additional sensor data is collected, which comprises kinematic sensor data (ZSD) and/or image data (BD) from at least one additional image-capturing unit (33). Key points (SP) are detected in the collected image data (BD). Furthermore, a first depth value (TW1) of a key point (SP) is determined on the basis of the additional sensor data and on the basis of the sequence of image data (BD) for each image of the sequence of images (BD). A key point comparison of key points (SP) of different images of the sequence of images of the image data (BD) of the single camera (32) is also carried out. In addition, the position (P-LM) of a key point (SP) identified as a landmark (LM) is estimated by triangulation on the basis of key points (SP) of successive images which have been identified as identical during the key point comparison, to initialise the landmark (LM). An improved position value (PV-LM) of the landmark (LM) is determined and a kinematic variable (v, P, a) is determined in a joint optimisation process on the basis of a weighted fusion of the estimated position (P-LM) and the first depth value (TW1). The invention also relates to a determining device (20). A rail vehicle (31) is additionally described.
Disclosed herein are contiguous DNA sequences encoding highly compact multi-input genetic logic gates for precise in vivo cell targeting, and methods of treating disease using a combination of in vivo delivery and such contiguous DNA sequences.
The invention relates to a compound of formula (I), wherein A1, A2and R1-R5 are as defined in the description and in the claims. The compound of formula (I) can be used as cannabinoid 2 preferential agonist.
C07D 405/14 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
C07D 401/04 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring- member bond
A61K 31/4439 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A61K 31/4427 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems
24.
NOVEL AZETIDINE-SUBSTITUTED PYRIDINE AND PYRAZINE COMPOUNDS AS INHIBITORS OF CANNABINOID RECEPTOR 2
The invention relates to a compound of formula (I) wherein A1and R1-R4 are as defined in the description and in the claims. The compound of formula (I) can be used as a medicament, via inhibition of the cannabinoid receptor 2 (CB2).
C07D 401/04 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring- member bond
A61K 31/4439 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
The invention relates to a movement determination device (10) for a vehicle (20), preferably a rail vehicle. The movement determination device (10) comprises an optical sensor unit (1) for sensing optical sensor data (OSD) from the surroundings of the vehicle (20). The movement determination device (10) also comprises an acceleration sensor unit (2), which is mechanically connected to the vehicle (20), but is movable relative to the vehicle (20). Part of the movement determination device (10) is also an evaluation unit (3) for determining a reference speed (vR) of the vehicle (20) on the basis of acceleration data (BD) of the acceleration sensor unit (2). In addition, the movement determination device (10) also comprises a scale determination unit (4) for determining a scale (MS) for the optical sensor data (OSD) on the basis of the determined reference speed (vR) of the vehicle (20) and the optical sensor data (OSD). Lastly, the movement determination device (10) comprises a speed determination unit (5) for determining the speed (vF) of the vehicle (20) on the basis of optical sensor data (OSD) sensed by the optical sensor unit (1) and on the basis of the determined scale (MS). The invention also relates to a vehicle (20). The invention additionally relates to a method for determining a movement of a vehicle (20). The invention relates to a movement determination device (10) for a vehicle (20), preferably a rail vehicle. The movement determination device (10) comprises an optical sensor unit (1) for sensing optical sensor data (OSD) from the surroundings of the vehicle (20). The movement determination device (10) also comprises an acceleration sensor unit (2), which is mechanically connected to the vehicle (20), but is movable relative to the vehicle (20). Part of the movement determination device (10) is also an evaluation unit (3) for determining a reference speed (vR) of the vehicle (20) on the basis of acceleration data (BD) of the acceleration sensor unit (2). In addition, the movement determination device (10) also comprises a scale determination unit (4) for determining a scale (MS) for the optical sensor data (OSD) on the basis of the determined reference speed (vR) of the vehicle (20) and the optical sensor data (OSD). Lastly, the movement determination device (10) comprises a speed determination unit (5) for determining the speed (vF) of the vehicle (20) on the basis of optical sensor data (OSD) sensed by the optical sensor unit (1) and on the basis of the determined scale (MS). The invention also relates to a vehicle (20). The invention additionally relates to a method for determining a movement of a vehicle (20).
Described herein are methods of producing glycosylated proteins in vitro and in vivo. The methods include using host cells to produce glycosylated proteins. Also described herein are glycosylated proteins produced using such methods and uses thereof.
A61K 39/00 - Medicinal preparations containing antigens or antibodies
C07K 14/285 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
A dough-based food product, an apparatus and method for production of the dough-based food product. A food product matrix to be foamed includes a proportion by weight of a starch-containing raw material and a proportion by weight of water. Gas that has been dissolved or is to be dissolved is introduced into the food product matrix to be foamed. The gas is dissolved under pressure in the food product matrix to be foamed. Gas bubbles are formed by expansion and increasing the volume with a resulting reduction in density of the dough as a result of bubble growth for formation of a foamed food product matrix of the food product to be produced. The foam is then stabilized. Gas is introduced into and dissolved in the aqueous component of the food product matrix to be foamed in a subcritical state below the critical point and at a pressure of 10 bar≤p
A23P 30/34 - Puffing or expanding by pressure release, e.g. explosion puffingPuffing or expanding by vacuum treatment by extrusion-expansion
A23L 7/178 - Preparation of puffed cereals from wholegrain or grain pieces without preparation of meal or dough by pressure release with or without heating
A21C 1/00 - Mixing or kneading machines for the preparation of dough
A21C 14/00 - Machines or equipment for making or processing dough, not provided for in other groups of this subclass
28.
SYSTEMS AND METHODS FOR RATE-COMPATIBLE POLAR CODES FOR GENERAL CHANNELS
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (Switzerland)
Inventor
Mondelli, Marco
Hassani, Hamed
Maric, Ivana
Hong, Songnam
Hui, Dennis
Abstract
According to certain embodiments, a transmit node in a wireless communications system includes a first universal rate-compatible polar encoder and a transmitter. The first universal rate-compatible polar encoder is configured for a family of two or more types of channels and encodes a plurality of information bits to provide a plurality of coded bits. The transmitter transmits the plurality of coded bits to a receive node.
H03M 13/00 - Coding, decoding or code conversion, for error detection or error correctionCoding theory basic assumptionsCoding boundsError probability evaluation methodsChannel modelsSimulation or testing of codes
29.
DEVICE AND METHOD FOR QUANTIFYING OPTICAL PROPERTIES OF TRANSPARENT MATERIALS
Disclosed are device and associated method for quantifying optical properties of at least partially transparent material samples. In an embodiment, the present invention is directed to a versatile device and method for quantifying optical properties such as, but not limited to, haze, transmittance and resolution, as well as the spatial distribution thereof, for a plurality of material samples. The method for determining the optical properties for a given sample may be based on an evaluation of the changes to the characteristics of the illumination light incurred by its interaction with said sample.
The present invention relates to a method for the production of a library comprising recombinant derivatives of the SH3 domain of the Fyn kinase of SEQ ID NO: 1 as well as a method for selecting from a library comprising recombinant derivatives of the SH3 domain of the Fyn kinase of SEQ ID NO: 1 one or more of said derivatives having a specific binding affinity to a protein or peptide.
G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
C40B 30/04 - Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
31.
METHODS AND SYSTEMS FOR DETERMINING AN OPTICAL AXIS AND/OR PHYSICAL PROPERTIES OF A LENS AND USE OF THE SAME IN VIRTUAL IMAGING AND HEAD-MOUNTED DISPLAYS
A method is proposed for determining an optical axis of a lens when the lens is provided at an unknown position and/or orientation. The method comprises: a) obtaining at least one direct image of a background comprising identifiable features; b) providing a lens between the background and a camera such that light rays pass from the background, through the lens before arriving at the camera; c) using the camera to obtain at least one indirect image comprising the background when viewed through the lens; d) identifying at least one identifiable feature in the direct image and a corresponding identifiable feature in the indirect image; and e) using the correspondences from d) to determine an optical axis of the lens without aligning the optical axis of the lens with respect to the camera.
Systems and methods for re-arranging a musical composition using augmented reality are disclosed. A user can be provided with one or more physical image markers representative of at least one of a musical entity and a musical style in which a musical track has been pre-recorded. Upon capturing a visual scene in which one or more of these physical image markers are included, an augmented reality version of the visual scene is displayed along with audio corresponding to the musical style(s) and/or entities represented by the one or more physical image markers.
Described herein are methods of producing glycosylated proteins in vitro and in vivo. The methods include using host cells to produce glycosylated proteins. Also described herein are glycosylated proteins produced using such methods and uses thereof.
In a method and apparatus for production of a foamed, dough-based food product, especially snack products or baked snacks, according to any of the above claims, comprising the method steps of: a) providing a food product matrix to be foamed, comprising a proportion by weight of a starch-containing raw material (R) and a proportion by weight of water (W), b) introducing a gas that has been dissolved or is to be dissolved into the food product matrix to be foamed, c) dissolving the gas under pressure in the food product matrix to be foamed, d) forming gas bubbles by expansion and increasing the volume with a resulting reduction in density of the dough as a result of bubble growth for formation of a foamed food product matrix of the food product to be produced, e) stabilizing the foam of the foamed food product matrix, a process or apparatus for production of a foamed, dough-based food product is to be provided, which places lower demands on equipment and maintenance in production. This is achieved in that, in method step b) and/or method step c), gas is introduced into and dissolved in the aqueous component of the food product matrix to be foamed in a subcritical state below the critical point and at a pressure of 10 bar ≤ p < critical pressure of the gas. A foamed, dough-based and gluten-free food product is also claimed, as is the use of the apparatus.
A21D 8/02 - Methods for preparing doughTreating dough prior to baking
A21D 13/00 - Finished or partly finished bakery products
A23L 7/178 - Preparation of puffed cereals from wholegrain or grain pieces without preparation of meal or dough by pressure release with or without heating
The present invention relates to a method for the production of a library comprising recombinant derivatives of the SH3 domain of the Fyn kinase of SEQ ID NO: 1 as well as a method for selecting from a library comprising recombinant derivatives of the SH3 domain of the Fyn kinase of SEQ ID NO: 1 one or more of said derivatives having a specific binding affinity to a protein or peptide.
G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
C40B 30/04 - Methods of screening libraries by measuring the ability to specifically bind a target molecule, e.g. antibody-antigen binding, receptor-ligand binding
36.
USE OF DERMATOPONTIN FOR MAINTAINING HEMATOPOIETIC STEM AND/OR PROGENITOR CELLS IN CULTURE
The present invention relates to the use of dermatopontin (DPT) or a functional fragment thereof for the maintenance of hematopoietic stem and/or progenitor cells in culture. The present invention further relates to a method for maintaining hematopoietic stem and/or progenitor cells in culture, the method comprising culturing the hematopoietic stem and/or progenitor cells in the presence of dermatopontin (DPT) or a functional fragment thereof. Furthermore, the present invention relates to a cell culture medium for the maintenance of hematopoietic stem and/or progenitor cells, wherein the cell culture medium comprises a medium and dermatopontin (DPT) or a functional fragment thereof and further optionally comprises serum/serum replacement, (a) reducing agent(s), and/or (an) antibiotic(s) as well as a kit comprising dermatopontin (DPT) or a functional fragment thereof and at least one of: (a) (a) cell culture medium; (b) one or more cytokines; (c) serum/serum replacement; (d) (a) reducing agent(s), and/or (e) (an) antibiotic(s).
Provided are compositions comprising a polymer and a solvent, which may be used for e.g. gel-processing. An example is a composition comprising a polyethylene polymer and a vegetable oil. The solvent may be a fairly poor solvent for the polymer. The solvent may be extracted from the composition using a supercritical fluid.
D01D 5/16 - Stretch-spinning methods using rollers, or like mechanical devices, e.g. snubbing pins
D01F 6/04 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from homopolymers obtained by reactions only involving carbon-to-carbon unsaturated bonds from polyolefins
D01F 13/04 - Recovery of starting material, waste material or solvents during the manufacture of man-made filaments or the like of synthetic polymers
A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
1. Method for connecting scaffold structures for tissue engineering applications, implants and transplants in surgery by means of layer-by-layer methods. 2.1 In tissue engineering applications, the ideal tissue adhesive should secure the relevant construct in the wound bed and facilitate, and if possible, promote the integration of the implant or transplant into the surrounding healthy tissue. In doing this, the tissue adhesive must not hinder the natural healing processes. 2.2 The solution according to the invention allows the targeted production of modular tissue constructs by the connection of porous membranes, woven fibres, pressed or sponge-type structures, particles or hydrogels with the aid of layer-by-layer (LbL) methods. Said method according to the invention of combining porous scaffold structures, membranes, structures consisting of woven fibres or pressed structures, particles and hydrogels, in a modular manner, to form complex tissue constructs, and of transferring these into tissue defects, is based on the coating of said shaped bodies with polyelectrolyte multilayers (PEM) which allow the adherence or bonding of neighbouring shaped bodies by chemical or biochemical processes. 3. The invention relates to the use of tissue adhesives in surgery, tissue engineering and regenerative medicine.
The present invention relates to a compound of formula (I), wherein R is defined as in the description and in the claims. The compound of formula (I) can be used as radiolabeled ligand.
Systems and methods for obtaining alternative versions of media content are provided. Digital purchasing technology can be integrated with content viewing technology to provide dynamic content discovery and the ability to easily and efficiently obtain alternative media content to enhance a user's viewing experience. Additionally, a user's viewing experience can be upgraded by easily and efficiently allowing for the viewing of previously obtained alternative media content.
H04N 21/472 - End-user interface for requesting content, additional data or servicesEnd-user interface for interacting with content, e.g. for content reservation or setting reminders, for requesting event notification or for manipulating displayed content
H04N 21/437 - Interfacing the upstream path of the transmission network, e.g. for transmitting client requests to a VOD server
H04N 21/8547 - Content authoring involving timestamps for synchronizing content
H04N 21/2343 - Processing of video elementary streams, e.g. splicing of video streams or manipulating encoded video stream scene graphs involving reformatting operations of video signals for distribution or compliance with end-user requests or end-user device requirements
H04N 21/462 - Content or additional data management e.g. creating a master electronic program guide from data received from the Internet and a Head-end or controlling the complexity of a video stream by scaling the resolution or bit-rate based on the client capabilities
H04N 21/482 - End-user interface for program selection
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Sensor units for use in robotics; software for use in robotics; sensor units for the purposes of positioning and/or navigating; software for the purposes of positioning and/or navigating. Scientific and industrial research and development services.
43.
5,6-DISUBSTITUTED PYRIDINE-2-CARBOXAMIDES AS CANNABINOID RECEPTOR AGONISTS
The invention relates to a compound of formula (I) wherein R1 to R4 are defined as in the description and in the claims. The compound of formula (I) are agonists of the Cannabinoid Receptor 2 and are therefore useful in the treatment of various diseases such as pain, atherosclerosis, inflammation etc.
C07D 401/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
C07D 405/14 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
C07D 413/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
C07D 401/04 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring- member bond
C07D 413/12 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
C07D 417/06 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
C07D 417/12 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a chain containing hetero atoms as chain links
A61K 31/4439 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
Provided are compositions comprising a polymer and a solvent, which may be used for e.g. gel-processing. An example is a composition comprising a polyethylene polymer and a vegetable oil. The solvent may be a fairly poor solvent for the polymer.
A targeted therapeutic agent comprising a compound of formula (I): B-L-D, wherein: B is a low molecular weight binding moiety for Carbonic Anhydrase IX (CAIX); D is a drug moiety; and L is a linker group that undergoes cleavage in vivo for releasing said drug moiety in an active form. The drug moiety is suitably a cytotoxic agent for targeted delivery to cancer cells expressing CAIX. The binding moiety B suitably comprises a sulfonamidothiadiazole moiety. The binding moiety B may comprise one, two or more groups capable of binding to CAIX. The linker group suitably comprises a disulfide bond and/or a triazole group and/or a cleavable peptide group.
A61K 47/54 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
A61K 47/65 - Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
C07K 5/027 - Peptides having up to four amino acids in a fully defined sequenceDerivatives thereof containing at least one abnormal peptide link in which at least a gamma-amino acid is involved, e.g. statine
A targeted therapeutic agent comprising a compound of formula (I): BLD, wherein: B is a low molecular weight binding moiety for Carbonic Anhydrase IX (CAIX); D is a drug moiety; and L is a linker group that undergoes cleavage in vivo for releasing said drug moiety in an active form. The drug moiety is suitably a cytotoxic agent for targeted delivery to cancer cells expressing CAIX. The binding moiety B suitably comprises a sulfonamidothiadiazole moiety. The binding moiety B may comprise one, two or more groups capable of binding to CAIX. The linker group suitably comprises a disulfide bond and/or a triazole group and/or a cleavable peptide group.
A61K 47/54 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
C07D 417/12 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a chain containing hetero atoms as chain links
A targeted therapeutic agent comprising a compound of formula (I): B–L–D, wherein: B is a low molecular weight binding moiety for Carbonic Anhydrase IX (CAIX); D is a drug moiety; and L is a linker group that undergoes cleavage in vivo for releasing said drug moiety in an active form. The drug moiety is suitably a cytotoxic agent for targeted delivery to cancer cells expressing CAIX. The binding moiety B suitably comprises a sulfonamidothiadiazole moiety. The binding moiety B may comprise one, two or more groups capable of binding to CAIX. The linker group suitably comprises a disulfide bond and/or a triazole group and/or a cleavable peptide group.
A61K 47/48 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
The present invention relates to a method for the production of a library comprising recombinant derivatives of the SH3 domain of the Fyn kinase of SEQ ID NO: 1 as well as a method for selecting from a library comprising recombinant derivatives of the SH3 domain of the Fyn kinase of SEQ ID NO: 1 one or more of said derivatives having a specific binding affinity to a protein or peptide.
A learning unit generates a function table indicating the relationship between the class number and position information of an object and the probability of appearance of the object for each small area image pattern of a code book, calculates a sharing matrix indicating the commonality of a feature amount between the classes, makes a tree diagram in which the classes with a similar feature amount are clustered, and calculates the weight of each node in the tree diagram for each small area image pattern. The recognition processing unit compares image data captured by a camera with the code book, selects the closest small area image pattern, extracts the class related to the node with the smallest weight among the nodes with a weight equal to or greater than a threshold value, and votes the position information of the small area image pattern for the class, thereby recognizing the object.
The present invention relates to mixed reality simulation in general, and more specifically to mixed reality simulation devices and systems for training purposes, for example in the medical field. The present invention proposes a mixed reality simulation method for rendering on a display a mixed reality scenario of a virtual environment adapted to a physical environment, the method comprising: acquiring, with a sensor, a position of a physical environment object; identifying a mismatch between a physical environment surface and a virtual environment surface, the mismatch depending on the physical environment object position and a mixed reality scenario parameter; and computing a mapping displacement for a virtual environment surface based on the identified mismatch.
A method for forming a semiconductor body, the method comprising: forming a mixture of an organic semiconducting material and a binder material; causing the semiconducting material to at least partially solidify; and causing the binder material to crystallize in such a way as to cause the semiconducting material to at least partially segregate from the binder material.
H01L 29/08 - Semiconductor bodies characterised by the shapes, relative sizes, or dispositions of the semiconductor regions with semiconductor regions connected to an electrode carrying current to be rectified, amplified, or switched and such electrode being part of a semiconductor device which comprises three or more electrodes
H01L 51/00 - Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof
H01L 51/05 - Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof specially adapted for rectifying, amplifying, oscillating or switching and having at least one potential-jump barrier or surface barrier; Capacitors or resistors with at least one potential-jump barrier or surface barrier
52.
POLYMER ARTICLES, AND METHODS AND DIES FOR MAKING THE SAME
Provided are polymer articles for use in, e.g., packaging application and/or applications requiring good barrier properties. Also disclosed are methods and tools for making the articles.
B32B 27/10 - Layered products essentially comprising synthetic resin as the main or only constituent of a layer next to another layer of a specific substance of paper or cardboard
A high temperature thermal barrier coating (13) which consists of a stabilized ZrO2 composition for the protection of thermally loaded components (10, 10') of a thermal machine, especially a gas turbine, is disclosed. Said thermal barrier coating (13) is stabilized with at least 15 mol% Y1+νTa1-νO4-ν, the ZrO2 is partially substituted by at least 10 mol% HfO2 and the composition is established according to the formula (Y1+νTa1-νO4-ν)z (Zr1-ϰHƒϰO2)1-z, with x ranging from 0.1 to 0.5, ν ranging from -0.1 to 0.2 and z ranging from 0.15 to 0.25.
C08K 9/04 - Ingredients treated with organic substances
C08F 2/44 - Polymerisation in the presence of compounding ingredients, e.g. plasticisers, dyestuffs, fillers
C08J 9/12 - Working-up of macromolecular substances to porous or cellular articles or materialsAfter-treatment thereof using blowing gases generated by a previously added blowing agent by a physical blowing agent
A learning processing unit (4) creates a function table representing the relationship between the class number and position information of an object and an occurrence probability, obtains a sharing matrix representing the commonality of a feature quantity among classes, creates a tree diagram in which classes having similar feature quantities are arranged, and calculates the weighting of each node in the tree diagram for each small region image pattern. A recognition processing unit (7) compares captured image data acquired by a camera (2) with a codebook, selects the closest small region image pattern from among a plurality of small region image patterns, extracts a class relating to the node having the smallest weighting from among nodes having weightings that are equal to or greater than a threshold with respect to the selected small region image pattern, and identifies the object by voting on the position information of the small region image pattern with respect to the extracted class.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE D'AIX-MARSEILLE (France)
Inventor
Maas, Werner
Rosay, Mélanie
Coperet, Christophe
Gajan, David
Emsley, Lyndon
Lelli, Moreno
Lesage, Anne
Rossini, Aaron
Zagdoun, Alexandre
Tordo, Paul
Ouari, Olivier
Abstract
Non aqueous solvents or mixtures for DNP NMR spectroscopy, method to prepare said solvents or mixtures and use of said solvents or mixtures The present invention concerns a method to determine the efficiency of a solvent to impregnate a sample material for use in a dynamic nuclear polarization (DNP) nuclear magnetic resonance (NMR) experiments, characterized in that the method comprising: - selecting a non-aqueous solvent, - providing a polarizing agent that is soluble in the non-aqueous solvent, - dissolving the polarizing agent in the non-aqueous solvent, - impregnating or dissolving the sample material with the non- aqueous solvent containing the polarizing agent, - performing a solid state DNP NMR experiment on the impregnated sample material, - determining a DNP enhancement factor of the DNP NMR experiment.
G01N 24/12 - Investigating or analysing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using double resonance
G01R 33/62 - Arrangements or instruments for measuring magnetic variables involving magnetic resonance using double resonance
G01R 33/28 - Details of apparatus provided for in groups
A method for operating on images is described for interest point detection and/or description working under different scales and with different rotations, e.g. for scale-invariant and rotation-invariant interest point detection and/or description.
G06K 9/46 - Extraction of features or characteristics of the image
G06K 9/66 - Methods or arrangements for recognition using electronic means using simultaneous comparisons or correlations of the image signals with a plurality of references, e.g. resistor matrix references adjustable by an adaptive method, e.g. learning
Provided are a device and a method for action prediction, capable of accurately estimating a movement action of a movable body. The action prediction device creates a likelihood map representing the adequacy of the next velocity vector of a pedestrian, on the basis of a photographed image of the pedestrian, and then, converts the likelihood map into a probability density map representing the probability density regarding a position of the pedestrian after a unit time. The action prediction device arranges a plurality of hypotheses in the field having a high probability density on the probability density map, and calculates a plurality of predicted moving courses corresponding to the hypotheses. The hypothesis in this case corresponds to a single point on the probability density map and means that the pedestrian moves at the velocity vector corresponding to the point during the next unit time. Therefore, a predicted moving course can be obtained from the velocity vector.
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
G08B 25/00 - Alarm systems in which the location of the alarm condition is signalled to a central station, e.g. fire or police telegraphic systems
G08G 1/04 - Detecting movement of traffic to be counted or controlled using optical or ultrasonic detectors
B60R 21/34 - Protecting non-occupants of a vehicle, e.g. pedestrians
60.
System and method for the remote monitoring of potted plants
The invention relates to a system and method for determining the state, state changes, and/or condition changes of a potted plant and for indicating the determined state of said object to the owner or user thereof, wherein the system and method locally determine at least one physical and/or chemical parameter on top of on the side of or in the immediate vicinity of the plant (1) to be monitored by means of preferably several sensors or sensing elements (3). Said physical and/or chemical parameter is processed into a coded digital parameter signal and transmitted wirelessly, optionally by means of intermediate stages, to a central processor, which determines a statement about the state of the plant (1) from said coded digital parameter signal and other digital as an optical and/or acoustic indication of the current or prognosticated state of the plant/object (1). The sensation of the object is preferably simulated, which aims at triggering emotions in the user himself, for example, by means of language- and culture-independent icons. The data are determined, processed, and transmitted without significant time delay, in other words, in real time in principle. In the central processing, the data can be combined with further information, for example, the requirements profile of the object, historical data, data of similar objects, climate data, or weather forecasts. The user of the system can automatically be contacted if certain events are ascertained for the monitored object, if for example, an unfavorable forecast or a harmful parameter is ascertained. The sensors or sensing elements and further components are preferably placed in a plant container, an “intelligent flowerpot” so to speak, in such a way that the sensors or sensing elements are undetectable or barely detectable. Said “intelligent flowerpot” can comprise a “mobile sensor clip” as an essential component in addition to sensors arranged therein or thereon.
Provided is a process in which a composition comprising a pi-conjugated material is shaped when the pi-conjugated material is in the solid state. Also provided are articles comprising pi-conjugated materials.
EMPA EIDG. MATERIALPRÜFUNGS- UND FORSCHUNGSANSTALT (Switzerland)
Inventor
Urban, Pawel
Zenobi, Renato
Jefimovs, Konstantins
Amantonico, Andrea
Fagerer, Stephan
Goedecke, Nils
Abstract
A sample support plate (100) for a variety of possible applications, including MALDI mass spectrometry, is disclosed. A plurality of spatially separated sample recipient sites (101) are arranged on the surface of a substrate. The recipient sites are mutually separated by areas having a different wettability than the recipient sites. They are arranged in a plurality of rows consisting of a plurality of recipient sites whose centers are regularly spaced along a first direction with a predetermined periodicity (D1), the rows being regularly spaced along a second direction perpendicular to the first direction with a predetermined centerline distance (D2). Each recipient site has a maximum lateral dimension that is preferably smaller than the diameter of a beam spot (104) of a desorption laser beam (103). In order to enable unsupervised splitting of bulk liquid samples into droplets at the sample recipient sites, the periodicity along the first direction and the centerline distance along the second direction are chosen such that each recipient sites has a next neighbor at a distance that is less than or equal to three times the minimum lateral dimension of each recipient site. In preferred embodiments, the sample recipient sites are arranged in a checkerboard-type pattern or in rows that are inclined relative to the edges of the sample support plate.
H01J 49/04 - Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locksArrangements for external adjustment of electron- or ion-optical components
H01J 49/16 - Ion sourcesIon guns using surface ionisation, e.g. field-, thermionic- or photo-emission
63.
Polymer articles, and methods and dies for making the same
Provided are dies having a first section for orienting material being pressed through the die and a second section for shaping the oriented material into a desired form. In an embodiment, the surface area for shaping the oriented material into a desired form is limited. Also provided are polymer articles and processes for making the same. In an embodiment, the processes employ the dies.
D04H 1/56 - Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties by welding together the fibres, e.g. by partially melting or dissolving in association with fibre formation, e.g. immediately following extrusion of staple fibres
B29C 47/00 - Extrusion moulding, i.e. expressing the moulding material through a die or nozzle which imparts the desired form; Apparatus therefor (extrusion blow-moulding B29C 49/04)
B29C 47/02 - incorporating preformed parts or layers, e.g. extrusion moulding around inserts or for coating articles
B29C 47/04 - of multilayered or multicoloured articles
The invention relates to a method for the determination of an MRM or SRM assay for a protein of interest, a peptide of interest, or a group of proteins/peptides of interest or a whole proteome. It essentially includes the following steps: (1) a list of proteins of interest is selected and for each member at least one or a list of candidate proteotypic peptides is derived (2) this at least one peptide is synthesized/generated essentially without subsequent purification; (3) this at least one unpurified peptide is analyzed by selected reaction monitoring (SRM) preferably coupled to liquid chromatography (LC-SRM) or analogous techniques; (4) validation and/or optimisation of the corresponding assay of the at least one peptide with determination of the SRM coordinates for a peptide/protein of interest and/or of a regulator of interest is achieved. A protein sample of interest is enzymatically digested and can then be analyzed in SRM mode or time-constrained SRM mode, using elution times to trigger acquisition of the set of selected SRM traces, thus drastically increasing the throughput. The analysis allows to detect and quantify the set of peptides/proteins of interest. The method additionally relates to a tagging strategy to achieve absolute quantification of the peptides/proteins of interest at low-budget and high-throughput.
G01N 31/00 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroupsApparatus specially adapted for such methods
A process for continuous or quasi-continuous purification of a multi-component mixture (F) by means of individual chromatographic columns through which the mixture is fed by means of at least one solvent(s). The multi-component mixture (F) at least comprises light impurities (A), an intermediate product (B) to be purified and heavy impurities (C), and the columns are grouped into at least four sections (α,β,γ,δ). After or within a switch time (t*) the last column from the first section (α) is moved to the first position of the second section (β), the last column of the second section (β) is moved to the first position of the third section (γ), the last column of the third section (γ) is moved to the first position of the fourth section (δ) and the last column of the fourth section (δ) is moved to become the first column of the first section (α).
A system for arm therapy comprises a first drive (M2) that can be fixedly connected to an element (10) determining the position of a user (19) and rotationally driving, about a first axis (A2), a part (21, 22, 23, 24, 25, M1, 26) of the arm therapy system which can be connected to an upper arm module (26, M3, M4). The driven part of the arm therapy system comprises a second drive (M1) adapted to rotationally drive said upper arm module (26, M3, M4) about a second axis (A1), wherein said second axis (A1) is oriented orthogonal to the first axis (A2). The system can provide a statically determined exoskeleton with correct anatomical axes and misaligned technical axes.
The present invention relates to Salmonella entehca comprising at least one pgl operon of Campylobacter jejuni or a functional derivative thereof and presenting at least one N- glycan of Campylobacter jejuni or N-glycan derivative thereof on its cell surface. In addition, it is directed to medical uses and pharmaceutical compositions thereof as well as methods for treating and/or preventing Campylobacter and optionally Salmonella infections and methods for producing these Salmonella strains.
The present invention relates to Salmonella entehca comprising at least one pgl operon of Campylobacter jejuni or a functional derivative thereof and presenting at least one N- glycan of Campylobacter jejuni or N-glycan derivative thereof on its cell surface. In addition, it is directed to medical uses and pharmaceutical compositions thereof as well as methods for treating and/or preventing Campylobacter and optionally Salmonella infections and methods for producing these Salmonella strains.
The invention relates to a system and method for determining the state, state changes, and/or condition changes of a potted plant and for indicating the determined state of said object to the owner or user thereof, wherein the system and method locally determine at least one physical and/or chemical parameter on top of, on the side of, or in the immediate vicinity of the plant (1) to be monitored by means of preferably several sensors or sensing elements (3). Said physical and/or chemical parameter is processed into a coded digital parameter signal and transmitted wirelessly, optionally by means of intermediate stages, to a central processor, which determines a statement about the state of the plant (1) from said coded digital parameter signal and other digital parameter signals, said statement finally being transmitted wirelessly in turn to the owner or user on an indication device (11) as an optical and/or acoustic indication of the current or prognosticated state of the plant/object (1). The sensation of the object is preferably simulated, which aims at triggering emotions in the user himself, for example, by means of language- and culture-independent icons. The data are determined, processed, and transmitted without significant time delay, in other words, in real time in principle. In the central processing, the data can be combined with further information, for example, the requirements profile of the object, historical data, data of similar objects, climate data, or weather forecasts. The user of the system can automatically be contacted if certain events are ascertained for the monitored object, if, for example, an unfavorable forecast or a harmful parameter is ascertained. The sensors or sensing elements and further components are preferably placed in a plant container, an "intelligent flowerpot" so to speak, in such a way that the sensors or sensing elements are undetectable or barely detectable. Said "intelligent flowerpot" can comprise a "mobile sensor clip" as an essential component in addition to sensors arranged therein or thereon.
The invention relates to scaffolds for artificial heart valves and vascular structures comprising a biocompatible block copolymer. A method and means for producing said scaffold are also provided.
B29C 67/00 - Shaping techniques not covered by groups , or
D04H 3/16 - Non woven fabrics formed wholly or mainly of yarns or like filamentary material of substantial length characterised by the method of strengthening or consolidating with bonds between thermoplastic yarns or filaments produced by welding with bonds between thermoplastic filaments produced in association with filament formation, e.g. immediately following extrusion
71.
POLYMER ARTICLES, METHODES AND DIES FOR MAKING THE SAME
Provided are dies (300, 600, 1000) having a first section for orienting material being pressed through the die (300, 600, 1000) and a second section for shaping the oriented material into a desired form. In an embodiment, the surface area for shaping the oriented material into a desired form is limited Also provided are polymer articles and processes for making the same. In an embodiment, the processes employ the dies (300, 600, 1000).
D04H 1/56 - Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties by welding together the fibres, e.g. by partially melting or dissolving in association with fibre formation, e.g. immediately following extrusion of staple fibres
B29C 69/02 - Combinations of shaping techniques not provided for in a single one of main groups , e.g. associations of moulding and joining techniquesApparatus therefor of moulding techniques only
The present invention relates to paromamine-based compounds according to formula I having selective antimicrobial activity directed at ribosomal 16S RNA. Furthermore, the invention is directed to the use of said compounds for preparing a medicament, pharmaceutical preparations and methods for preparing said compounds.
A method for forming a semiconductor body, the method comprising: forming a mixture of an organic semiconducting material and a binder material; causing the semiconducting material to at least partially solidify; and causing the binder material to crystallize in such a way as to cause the semiconducting material to at least partially segregate from the binder material.
H01L 33/16 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by the semiconductor bodies with a particular crystal structure or orientation, e.g. polycrystalline, amorphous or porous
74.
PHENOLIC CONFIGURATIONALLY LOCKED POLYENE BULK SINGLE CRYSTALS, CRYSTALLINE THIN FILMS AND WAVEGUIDES FOR ELECTRO-OPTICS AND THZ-WAVE APPLICATIONS
The invention concerns Phenolic Configurationally Locked Polyene Single Crystals, which are especially suited as highly efficient nonlinear optical organic material. The invention also concerns methods for growth of crystalline thin films or bulk crystals from melt and/or solution. The compounds are suited and the methods may be used for manufacturing optical elements for several bulk and integrated applications, e.g. electro-Optics and THz-Wave applications.
b) for receiving and/or emitting a radio frequency signal. The coil is attached to and extends along a face of the flexible sheet. At least part of the coil is made of a ribbon shaped braided conductor (6) that is arranged in substantially flat contact with the face.
Disclosed is a method for depositing an alloy and/or chemical compounds on a substrate immersed in an electrolyte (1), comprising the steps of: I) applying a first constant or varying potential to the substrate under voltage control for a first time interval (tA); II) applying a second constant or varying current to the substrate under current control for a second time interval (tB); repeating the sequence of steps (I-II). at least twice. Further the use of the method in particular for the deposition of Bi2+xTe3-x is disclosed as well as a specific device for carrying out the above method.
The present invention relates to a novel process for the remote plasma surface treatment of substrate particles at atmospheric pressure. The invention is motivated by the urge to overcome major drawbacks of particle treatment in low pressure plasmas and in-situ particle treatment at atmospheric pressure. The former requires complex and mostly expensive vacuum installations and vacuum locks usually prohibiting continuous processing. Independent of the system pressure, in-situ plasma treatment causes particle charging and therefore undesirable interaction with the electric field of the discharge, which is seen to contribute to the process of reactor clogging. Additionally, the filamentary discharges modes of atmospheric pressure plasmas are inflicted with inhomogeneous surface treatment. Furthermore, short radical lifetimes at elevated pressures complicate a remote plasma treatment approach as widely used in low pressure applications. The key- element of the invention is that by reducing the dimension of the atmospheric discharge arrangement to the micrometer range, transonic flow conditions can be achieved in the discharge zone while maintaining moderate flow rates. The resulting superimposition of high drift velocity in the gas flow and the inherent diffusion movement is to prolong the displacement distance of activated species, thus making a remote plasma treatment of substrate particles feasible and economically interesting. The circumferential arrangement of e.g. micro discharge channels around the treatment zone of variable length allows a remote plasma treatment independently of the discharge mode and benefits additionally from the aerodynamic focusing of a particle-gas stream to the centre, reducing reactor clogging. Furthermore, taking advantage of non-thermal discharges, there is no restriction of the concept of the outlined invention in the material properties of the particulate solids especially not with regard to the treatment of temperature sensitive materials as often encountered in polymer or pharmaceutical industries. In conclusion, atmospheric pressure plasma treatment close to ambient gas temperature as well as continuous processing is a specialty of the invention disclosed here.
The present document relates to a method for producing macro-porous materials comprising the following steps: a) synthesis of narrowly dispersed cross-linked polymeric particles starting from a monomer and a cross-linker in an emulsion polymerization; b) swelling of the particles with a liquid comprising at least an additional charge of monomer and cross-linker and subsequent destabilisation; c) initiating the reaction of the swelled particles to form a monolithic structure. The corresponding monolithic structures can be very efficiently functionalised if after the synthesis of the polymeric particles in step a) and before the initiation of the reaction of the swelled particles in step c) the polymeric particles are chemically functionalised or prepared for subsequent functionalization of the monolithic structure.
A61K 39/00 - Medicinal preparations containing antigens or antibodies
B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties
For retrieving information based on images, a first image is taken (S1 ) using a digital camera associated with a communication terminal (1). Query data related to the first image is transmitted (S3) via a communication network (2) to a remote recognition server (3). In the remote recognition server (3) a reference image is identified (S4) based on the query data. Subsequently, in the remote recognition server (3), a Homography is computed (S5) based on the reference image and the query data, the Homography mapping the reference image to the first image. Moreover, in the remote recognition server(3), a second image is selected (S6) and a projection image is computed (S7) of the second image using the Homography. By replacing a part of the first image with at least a part of the projection image, an augmented image is generated (S8, S10) and displayed (S11) at the communication terminal (1). Efficient augmentation of the first image taken with the camera is made possible by remaining in the planar space and dealing with two-dimensional images and objects only.
The present invention relates to paromamine-based compounds according to formula (I) having selective antimicrobial activity directed at ribosomal 16S RNA. Furthermore, the invention is directed to the use of said compounds for preparing a medicament, pharmaceutical preparations and methods for preparing said compounds.
C07H 15/232 - Cyclohexane rings, substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to adjacent ring-carbon atoms of the cyclohexane rings with at least three saccharide radicals in the molecule, e.g. lividomycin, neomycin, paromomycin
A61K 31/7036 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
Electrochemical biosensor arrays and systems, as well as methods of making the electrochemical biosensor arrays and systems, are described herein. The electrochemical biosensor systems can be used with CMOS detection circuits that have a plurality of chemical detection and/or actuation channels or sites. The biosensor systems generally include a first inert conducting electrode disposed on a first portion of a CMOS detection circuit and a polymeric layer adjacent the first inert conducting electrode. The biosensor systems can also include a capture biomolecule bound to the polymeric layer. The biosensor system can also include the CMOS detection and/or actuation circuit having a plurality of channels.
The present invention provides for novel sustained release silk-based delivery systems. The invention further provides methods for producing such formulations. In general, a silk fibroin solution is combined with a therapeutic agent to form a silk fibroin article. The article is then treated in such a way as to alter its conformation. The change in conformation increases its crytallinity or liquid crystallinity, thus controlling the release of a therapeutic agent from the formulation. This can be accomplished as single material carriers or in a layer-by-layer fashion to load different therapeutic agents or different concentrations of these agents in each layer.
A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
A61K 9/22 - Sustained or differential release type
83.
SPECIFIC AND HIGH AFFINITY BINDING PROTEINS COMPRISING MODIFIED SH3 DOMAINS OF FYN KINASE
The present invention relates to a recombinant binding protein comprising at least one derivative of the Src homology 3 domain (SH3) of the FYN kinase, wherein at least one amino acid in or positioned up to two amino acids adjacent to the src loop and/or at least one amino acid in or positioned up to two amino acids adjacent to the RT loop is substituted, deleted or added. Furthermore, the invention is directed to fusion proteins comprising a binding protein according to the invention fused to a pharmaceutically and/or diagnostically active component. In addition, the invention concerns nucleotides coding for these binding and/or fusion proteins as well as corresponding vectors and host cells. Last but not least, the present invention relates to the use of binding and/or fusion proteins of the present invention for preparing a medicament or a diagnostic means as well as to pharmaceutical or diagnostic compositions comprising said binding and/or fusion proteins.
C07K 14/435 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
Method for determining the specific heat capacity (cp) of a medium with a calorimeter, said calorimeter comprises a reactor (1), a stirrer (3), a first thermostat for providing an inner heat balance, a second thermostat, means for providing an outer heat balance and a central control unit (35), characterized in that the method comprises the following steps applying a modulated energy profile to the medium which is arranged inside the reactor (1) under near isothermal conditions; monitoring the resulting energy changes of at least one of the following the medium, the reactor (1), the first thermostat, the second thermostat and/or said means for providing an outer heat balance as a function of time; determining the inner heat balance and the outer heat balance independently from each other at predefined time intervals; and calculating the overall heat transfer coefficient (UA) and the specific heat capacity of the medium (cp) simultaneously and independently from each other as a function of time from the inner and outer heat balance.
G01N 25/00 - Investigating or analysing materials by the use of thermal means
G01N 25/20 - Investigating or analysing materials by the use of thermal means by investigating the development of heat, i.e. calorimetry, e.g. by measuring specific heat, by measuring thermal conductivity
G01K 17/04 - Calorimeters using compensation methods
A method for forming a semiconductor body, the method comprising: forming a mixture of an organic semiconducting material and a binder material; causing the semi conducting material to at least partially solidify; and causing the binder material to crystallize in such a way as to cause the semi conducting material to at least partially segregate from the binder material.
The invention relates to a membrane comprising a biocompatible block copolymer and has a porous structure with regularly distributed pores. A method for preparing said membranes is also provided.
The invention relates to scaffolds for artificial heart valves and vascular structures comprising a biocompatible block copolymer. A method and means for producing said scaffold are also provided.
The method for generating a 3D representation of a dynamically changing 3D scene, comprises the steps of acquiring at least two synchronised video streams (120) from at least two cameras located at different locations and observing the same 3D scene (102); determining camera parameters, which comprise the orientation and zoom setting, for said at least two cameras (103); tracking the movement of objects (310a,b, 312a,b; 330a,b, 331a,b, 332a,b; 410a,b, 411a,b; 430a,b, 431a,b; 420a,b, 421a,b) in the at least two video streams (104); determining the identity of said objects in the at least two video streams (105); determining the 3D position of the objects by combining the information from the at least two video streams (106); wherein the step of tracking (104) the movement of objects in the at least two video streams uses position information derived from the 3D position of the objects in one or more earlier instants in time. As a result, the quality, speed and robustness of the 2D tracking in the video streams is improved.
A sealing system for blocking or attenuating microwave energy (14) between two environments or regions of space (1, 2) includes an electromagnetic bandgap (EBG) seal (20) mounted within an opening (3) in the partition (4) that separates the two environments or regions of space (1, 2) from each other. The EBG seal (20) consists of an EBG structure (21) secured to one side of the opening (3), an electrically conducting surface (12) secured to the other side of the opening, and a dielectric volume (11) between the EBG structure (21) and the electrically conducting surface (12). Transmission spectral response of the EBG seal (20) features one or more distinct stop bands (bandgaps), as shown in Fig. 1 B, that the seal (20) operates in. Said EBG structure especially refers to any metallodielectric structure with substantially periodic metallization and featuring inherent frequency bands where propagation of electromagnetic energy is forbidden and allowed. Typical EBG structure may consist of substantially periodically-spaced electrically conducting patches (31) placed on, or embedded in, a dielectric layer (32) that is backed by an electrically conducting surface (33). The electrically conducting patches (31) may be connected to the electrically conducting surface by electrically conducting posts (34).
Methods and apparatus for operating on images are described, in particular methods and apparatus for interest point detection and/or description working under different scales and with different rotations, e.g. for scale- invariant and rotation-invariant interest point detection and/or description. The present invention can provide improved or alternative apparatus and methods for matching interest points either in the same image or in a different image. The present invention can provide alternative or improved software for implementing any of the methods of the invention. The present invention can provide alternative or improved data structures created by multiple filtering operations to generate a plurality of filtered images as well as data structures for storing the filtered images themselves, e.g. as stored in memory or transmitted through a network. The present invention can provide alternative or improved data structures including descriptors of interest points in images, e.g. as stored in memory or transmitted through a network as well as datastructures associating such descriptors with an original copy of the image or an image derived therefrom, e.g. a thumbnail image.
The present invention relates to a method of detecting among a population of candidate biocatalysts a biocatalyst capable of catalyzing a chemical conversion reaction from a substrate to a product, said method comprising the steps of: a) providing a host cell comprising: - at least one product-inducible expression system comprising nucleic acid encoding at least one detector gene operably linked to a regulatory element, wherein the expression of said detector gene is inducible by said product, and - at least one biocatalyst expression system comprising nucleic acid encoding at least one candidate biocatalyst, wherein said at least one candidate biocatalyst is selected from said population of candidate biocatalysts, b) contacting said host cell with said substrate under conditions wherein said nucleic acid encoding at least one candidate biocatalyst is expressed in said host cell and wherein said substrate is allowed to contact said candidate biocatalyst, and wherein said substrate is converted into said product in case said candidate biocatalyst is capable of catalyzing said reaction, and c) detecting said host cell as one comprising a biocatalyst capable of catalyzing said chemical conversion reaction on the basis of the expression of said detector gene.
The disclosure pertains to a method for determining a crystal structure comprising the steps of initialisation, local optimisation, selection, production of the next generation with the help of variation operators wherein as variation operators genetic crossover, mutation and permutation are used, wherein the simulation is terminated after it converges to a global minimum.
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
A sheet-like substrate (34) is coated with at least one thin film (36') composed of at least one porous ceramic layer (S'1, S'2, S'3,...). A solution or a suspension of an organic and/or inorganic metal composite as starting material (14) is admixed with a mixed-in, insoluble pore former (18) and the mixture (22) is sprayed on as layer (S'1, S'2, S'3,...) of a thin film (36). The pore former (18) is at least partly thermally decomposed and/or burnt out to form an at least partly open-pored structure. The process is particularly suitable for producing miniaturized devices such as fuel cells and gas sensors.
G01N 27/26 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variablesInvestigating or analysing materials by the use of electric, electrochemical, or magnetic means by using electrolysis or electrophoresis
H01M 8/12 - Fuel cells with solid electrolytes operating at high temperature, e.g. with stabilised ZrO2 electrolyte
94.
HETEROCYCLIC COMPOUNDS AND THEIR USE AS ANTIFOULING AGENTS
The present invention relates to a nostocarboline compound of the formula (I) and its use as a biocidal agent. Formula (I) In this formula R1, R3, R4 and Re are selected from the group consisting of H, F, Cl, Br, I, a C1-C20 aliphatic residue, and a C1-C20 aliphatic residue comprising a carbocyclic or heterocyclic residue; R2 is selected from the group consisting of H and Cl; R5 is selected from the group consisting of H, a C1-C20 aliphatic residue, and a C1-C20 aliphatic residue comprising a carbocyclic or heterocyclic residue; R7 is selected from the group consisting of a C1-C20 aliphatic residue, a C1-C20 aliphatic residue comprising a carbocyclic or heterocyclic residue, and a linker bound to a bioactive factor; R8 is selected from the group consisting of H, a C1-C6 aliphatic carboxylic acid, ester, or amide, and a C1-C20 carbocylic residue; and X- is a negatively charged ion.
C07D 519/00 - Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups or
A61P 31/00 - Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
A61K 31/437 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
A01N 43/90 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
95.
THIN FILM AND COMPOSITE ELEMENT PRODUCED FROM THE SAME
The invention relates to a thin film (10) consisting of at least two layers (S1, S2, S3 ) of a ceramic material, a ceramic and metallic material, or in the case of several layers (S1, S2, S3 ) a metallic material. All layers (S1, S2, S3 ) of the thin film (10) have a maximum average particle size (K) of approximately 500 nm and at least two layers consist of different material. In at least one of said layers, an essentially stable average particle size (K) remains after a relaxation time (t), even in an increased temperature range (T). The mechanical stability is preferably reinforced by a supporting, essentially flat substrate (12). In the composite element (13), the thickness (ds) of the substrate (12) is at least five times and in particular between ten and a hundred times the thickness dD of the thin film (10). The composite element (13) can be successfully used in a miniaturised electrochemical device, in particular in a solid oxide fuel cell SOFC (18), a sensor (36) or as a gas separation membrane (17).
The invention relates to a composite element (13) comprising a thin film (10) that consists of at least two layers (S1, S2, S3) of an oxide-ceramic and metallic material, or a metallic material and an essentially flat substrate (12) that supports the thin film (10). Said substrate is composed of a ceramicizable glass, a glass ceramic, a hybrid form or an intermediate product. To produce the substrate, selected regions are dissolved out of the photostructurable glass substrate (12). The composite element (13) can be successfully used in a miniaturised electrochemical device, in particular in a solid oxide fuel cell SOFC (18), a sensor (36) or as a gas separation membrane (17).
A method to control the velocity of a treadmill according to the walking velocity of the person that is using the treadmill . A reaction force is measured, which occurs when a longitudinal repulsion force is created between the treadmill (2) and the person (1). A signal representation for said reaction force is transmitted to a control unit. The control unit is used to control the velocity of the treadmill.
A61H 3/00 - Appliances for aiding patients or disabled persons to walk about
A61F 5/01 - Orthopaedic devices, e.g. long-term immobilising or pressure directing devices for treating broken or deformed bones such as splints, casts or braces
A61H 1/02 - Stretching or bending apparatus for exercising
A63B 22/02 - Exercising apparatus specially adapted for conditioning the cardio-vascular system, for training agility or co-ordination of movements with movable endless bands
98.
UNIQUE LABEL FOR IDENTIFICATION OR SECURITY SYSTEM
Unique labels for security or identification purposes, methods of making the labels and uses for the labels are described herein. The label is formed from one or more crystalline materials, optionally in combination with a non- crystalline material, or from a combination of polymers, and has a unique, detectable pattern. In one embodiment, the label is formed from a crystalline material, preferably a metallic material, which naturally contains a unique grain structure, with unique reflective properties. In a preferred embodiment, the label is formed of a metallic material that has been recrystallized to enlarge the size of the grains so that they are visible to the unaided human eye.
G09F 3/00 - Labels, tag tickets, or similar identification or indication meansSealsPostage or like stamps
B42D 15/10 - Identity, credit, cheque or like information-bearing cards (record carriers, e.g. credit or identity cards, for use with machines and with at least a part designed to carry digital markings G06K 19/00)
B42D 15/00 - Printed matter of special format or style not otherwise provided for
G07D 7/12 - Visible light, infrared or ultraviolet radiation
G06K 19/06 - Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
99.
METHOD AND SYSTEM FOR ACQUIRING AZIMUTH INFORMATION USING SIGNALS PROVIDED BY SATELLITES
A method and system for acquiring azimuth information of a device using signals transmitted from satellites comprises an antenna (4) for global positioning systems having at least a hemispherical antenna pattern covering at least part of the sky above the antenna (4) and is mounted together with the device. Modulation means cause a modulation over time of at least one receivable satellite signal for a predetermined azimuth angle area, and a control unit with calculating means to calculate the direction of the device through evaluation of the modulated satellite signals .
G01S 3/40 - Systems for determining direction or deviation from predetermined direction using adjustment of real or effective orientation of directivity characteristic of an antenna or an antenna system to give a desired condition of signal derived from that antenna or antenna system, e.g. to give a maximum or minimum signal adjusting orientation of a single directivity characteristic to produce maximum or minimum signal, e.g. rotatable loop antenna or equivalent goniometer system
G01S 5/02 - Position-fixing by co-ordinating two or more direction or position-line determinationsPosition-fixing by co-ordinating two or more distance determinations using radio waves
100.
Lactobacillus sp. with antimicrobial activities for the use as natural preservation system
Lactobacillus. Furthermore, food, feeding stuff and medicaments comprising such a mixture, a method for manufacturing and storing such goods and the use of the mixture to inhibit fungi and bacteria are provided.
