|
|
Found results for
 patents
1.
|
COMPOSITIONS PROVIDING ENHANCED ANTIBACTERIAL ACTIVITY AGAINST GRAM-POSITIVE BACTERIA AND USE THEREOF
| Application Number |
US2020018724 |
| Publication Number |
2020/172206 |
| Status |
In Force |
| Filing Date |
2020-02-19 |
| Publication Date |
2020-08-27 |
| Owner |
AGILE SCIENCES, INC. (USA)
|
| Inventor |
|
Abstract
A method of inhibiting, reducing growth of or destroying gram positive bacteria comprising contacting the gram positive bacteria with an effective amount of a 2-(substituted-amino)-imidazole compound and with an additional antibacterial compound separately, simultaneously, or sequentially, whereby the two compounds provide an antibiotic potentiation effect against the gram-positive bacteria. The additional antibacterial compound may comprise penicillin, daptomycin, vancomycin, oxacillin, linezolid, or related antibiotic(s).
IPC Classes ?
- C07D 501/48 - Methylene radicals, substituted by hetero rings
- C07D 501/50 - Methylene radicals, substituted by hetero rings with the 7-amino radical acylated by an aliphatic carboxylic acid, which is substituted by hetero atoms
- C07D 505/24 - Nitrogen atoms further acylated by radicals derived from carboxylic acids or by nitrogen or sulfur analogues thereof with the acylating radicals further substituted by hetero atoms or by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen further substituted by doubly-bound nitrogen atoms
|
2.
|
2-AMINOIMIDAZOLE-PHENYL DERIVATIVES USEFUL FOR CONTROLLING MICROBIAL GROWTH
| Application Number |
US2018021474 |
| Publication Number |
2018/169752 |
| Status |
In Force |
| Filing Date |
2018-03-08 |
| Publication Date |
2018-09-20 |
| Owner |
- NORTH CAROLINA STATE UNIVERSITY (USA)
- AGILE SCIENCES, INC. (USA)
|
| Inventor |
- Melander, Christian
- Jung, David Kendall
- Reyes, Samuel Onofre
|
Abstract
Provided are 2-aminoimidazole-phenyl derivative compounds of Formula (I): which compounds are useful in methods of controlling microbial growth, such as by enhancing the effects of an antibiotic administered in combination with the compound. Compositions including these compounds, devices including these compounds, and methods of using the same are also provided.
|
|
