Provided is a tri-agonist polypeptide compound targeting a GLP-1 receptor, a glucagon receptor and a GIP receptor, wherein the polypeptide compound can selectively act on the GLP-1 receptor, the glucagon receptor and the GIP receptor, so as to exert the activities of GLP-1, glucagon and GIP at the same time, and the polypeptide compound has a unique agonistic activity proportion for the three receptors, thus achieving better glucose reduction, weight reduction and lipid regulation effects.
A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
24222422O are inversed by means of the information acquisition and analysis system. The apparatus has a simple structure, satisfies the research requirements for simultaneous measurement of various greenhouse gases under the same path, greatly improves the utilization efficiency of the integrated cavity, and reduces measurement costs.
G01N 21/39 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using tunable lasers
G01N 21/01 - Arrangements or apparatus for facilitating the optical investigation
3.
Device for collaborative detection of carbon and nitrogen emissions and method thereof
2O can be inverted through the information acquisition and analysis system. This device meets the research demand for simultaneous detection of multiple greenhouse gases under the same path, greatly improving the utilization efficiency of the integrating cavity and saving detection costs.
G01N 21/39 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using tunable lasers
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
4.
HIGH-THERMAL-CONDUCTIVITY AND HIGH-LUMINOUS-EFFICIENCY COMPOSITE FLUORESCENT CERAMIC FOR LASER ILLUMINATION, AND PREPARATION METHOD THEREFOR
231-xx3512233 ceramic powder, and the fluorescent ceramic biscuit is subjected to dry pressing molding, vacuum sintering, air annealing and surface polishing treatment to obtain a composite fluorescent ceramic. The prepared composite ceramic achieves high-brightness white light emission under excitation of a blue light LD chip with a wavelength of 455 nm, and has a bearable excitation power density of 45-55 W/mm2, a luminous efficiency of 200-260 lm/W and a thermal conductivity of 20-26 Wm-1k-1.
C04B 35/44 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxides based on aluminates
JIANGSU XIYI ADVANCED MATERIALS RESEARCH INSTITUTE OF INDUSTRIAL TECHNOLOGY CO., LTD (China)
XUZHOU ALL TO PHOTOELECTRIC TECHNOLOGY CO., LTD (China)
XUZHOU EAGLED TECHNOLOGY CO., LTD (China)
Inventor
Zhang, Le
Liu, Xuanchu
Wang, Jinhua
Min, Chang
Li, Yanbin
Kang, Jian
Zhou, Chunming
Zhou, Tianyuan
Chen, Hao
Huang, Guocan
Wu, Xiaodong
Abstract
2424244 remarkably inhibits grain growth of LuAG, and makes the particle distribution of a Ce:LuAG ceramic small and uniform, and the prepared complex-phase fluorescent ceramic has high brightness and high luminous efficiency. The fluorescent ceramic has better luminescence characteristics, and solves the problems in the prior art of poor thermal stability, low light conversion efficiency and the like, and the preparation method for the complex-phase ceramic is simple, involves a short process and a low sintering temperature, can be applied to high-power LEDs/LDs devices, and greatly improves the application value of the devices.
C04B 35/50 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on rare earth compounds
C04B 35/44 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxides based on aluminates
C04B 35/622 - Forming processesProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products
A laser and method for generating an electromagnetic wave signal having high phase coherence. A distributed reflective optical fiber laser resonant cavity is formed by a non-polarization-maintaining gain optical fiber and a pair of fiber Bragg gratings of which both ends are written by a femtosecond laser direct-writing and line-etching method. During optical fiber grating writing, a tiny included angle is introduced between the projection of a laser line-etching direction on a horizontal plane where a central axis of an optical fiber core is located and a radial direction of the optical fiber core, and a tiny included angle is introduced between the laser line-etching direction and the horizontal plane where the central axis of the optical fiber core is located. The laser resonant cavity generates a three-wavelength laser output signal and eventually a millimeter wave or terahertz wave is generated between the output signals for outputting.
JIANGSU XIYI ADVANCED MATERIALS RESEARCH INSTITUTE OF INDUSTRIAL TECHNOLOGY CO., LTD (China)
XUZHOU ALL TO PHOTOELECTRIC TECHNOLOGY CO., LTD (China)
XUZHOU EAGLED TECHNOLOGY CO., LTD (China)
Inventor
Zhang, Le
Liu, Mingyuan
Zhu, Lv
Wei, Cong
Shao, Cen
Kang, Jian
Zhou, Chunming
Zhou, Tianyuan
Chen, Hao
Huang, Guocan
Wu, Xiaodong
Abstract
A composite fluorescent ceramic optical fiber with a high luminous efficiency and a high color rendering index, and a preparation method therefor. The composite fluorescent ceramic optical fiber is composed of a fiber core and a cladding, wherein the fiber core layer is prepared from a Ce ion-doped yellow fluorescent ceramic, and the cladding is prepared from an ion co-doped red fluorescent ceramic. The composite fluorescent ceramic optical fiber is prepared by means of a gel casting method. By using the design structure, energy transfer between Ce ions and other ions can be achieved, so as to realize spectrum red shift, thereby increasing the color rendering index, and the luminous efficiency can also be significantly improved. In addition, the diameter of the optical fiber is better matched with the size of a laser spot, such that the problem of "yellow ring effect" caused by the mismatching of the size of the laser spot and a ceramic light-emitting surface is effectively solved, and the illumination effect is good; and the heat dissipation problem during high-power LD pumping can be effectively solved, thereby facilitating long-term stable illumination.
C04B 35/44 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxides based on aluminates
8.
LASER AND METHOD FOR GENERATING ELECTROMAGNETIC WAVE SIGNAL HAVING HIGH PHASE COHERENCE
A laser and method for generating an electromagnetic wave signal having high phase coherence. A distributed reflective optical fiber laser resonant cavity is formed by a non-polarization-maintaining gain optical fiber (1) and a pair of fiber Bragg gratings (11, 12) of which both ends are written by a femtosecond laser direct-writing and line-etching method. During fiber grating writing, a tiny included angle (8) is introduced between the projection of a laser line-etching direction (6) on a horizontal plane (4) where a central axis (3) of an optical fiber core is located and a radial direction (7) of the optical fiber core, and a tiny included angle (9) is introduced between the laser line-etching direction (6) and the horizontal plane (4) where the central axis (3) of the optical fiber core is located. The laser resonant cavity generates, by means of pumping of a pumping light source (13), a three-wavelength laser output signal related to high linear polarization, single-frequency narrow line width and phase height, and finally a millimeter wave or terahertz wave is generated by means of a beat frequency between output signals for outputting. The present invention can implement the output of a multi-frequency millimeter wave or terahertz wave having stable phase height, and has a simple process, low manufacturing cost and higher mechanical stability.
A corona charge-based gallium oxide thin film deposition system and thin film deposition method. A substrate is placed in a substrate groove of a reaction region, and a carrier gas and a dilution gas are respectively introduced from an atomization tank and a dilution gas passage to a heating apparatus so that said gases fill the reaction region; a precursor solution is added into the atomization tank; the working temperature of the heating apparatus is set; the atomization frequency of an atomization apparatus in the atomization tank is set so that the precursor-containing solution is atomized into an aerosol precursor; a pulse charging unit is turned on form a spatial domain, and a discharge needle discharges, so that the aerosol precursor collides with charged particles in a space ionization zone, thus charging the aerosol precursor and moving same to a deposition region. A thin film is formed by deposition growth. By means of adding a pulse charging unit to existing Mist-CVD equipment, the deposition system and method may effectively reduce the waste of raw materials during a thin film deposition process and increase the deposition efficiency.
C23C 16/44 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating
C23C 16/448 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating characterised by the method used for generating reactive gas streams, e.g. by evaporation or sublimation of precursor materials
C30B 25/08 - Reaction chambersSelection of materials therefor
10.
PREPARATION METHOD FOR YAG-BASED TRANSPARENT CERAMIC HAVING LARGE-SCALE THIN SHEET COMPOSITE STRUCTURE
x1-x35123x1-x51212, then performing water-based tape casting with one YAG-based raw material powder to obtain a YAG-based ceramic green blank, preparing the other YAG-based raw material powder for water-based gel tape casting to obtain a slurry for tape casting on the YAG ceramic green blank, so as to obtain a YAG-based ceramic green blank having a composite structure, then drying and debinding; vacuum sintering the green body following debinding, and then annealing to obtain a transparent ceramic having a composite structure. The preparation method effectively prevents interface melting, long diffusion distance of a dual-system slurry, etc., which occur in a traditional preparation process for a ceramic thin sheet material having a composite structure, which can directly realize the preparation of a green blank larger than 1 mm, and is suitable for the industrial production of YAG-based transparent ceramics.
C04B 35/44 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxides based on aluminates
C04B 35/50 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on rare earth compounds
C04B 35/622 - Forming processesProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products
11.
GREEN LIGHT SOURCE WITH HIGH-SATURATION POWER DENSITY
A green light source with a high-saturation power density, comprising a blue light LD (1), an optical filter (2), a lens I (3), a light-emitting element (4), and a lens II (5) placed on a side face, which are sequentially arranged from bottom to top, wherein the light-emitting element (4) comprises a CE:LuAG transparent fluorescent ceramic rod (41), a reflector (42) located below the CE:LuAG transparent fluorescent ceramic rod (41), and a heat dissipation substrate (43) wrapping around the CE:LuAG transparent fluorescent ceramic rod (41), and the three are a "reflection type + inner total reflection type" encapsulation structure. The blue light LD (1) is configured to emit a laser; the optical filter (2) is obliquely placed at 45 degrees, and is configured to transmit the laser and reflect fluorescence; the lens I (3) is configured to focus the laser; the Ce:LuAG transparent fluorescent ceramic rod (41) emits green light to the periphery under the excitation of the laser, and is limited by the manner of encapsulation to emit green light in a vertical direction; the reflector (42) reflects the green light upwards; the heat dissipation substrate (43) is configured to perform ceramic heat dissipation; and the lens II (5) is configured to collect and further shape the green light reflected by the optical filter (2). According to the green light source with the high-saturation power density, the saturation power density of the green light source can be increased, the luminous efficiency is higher, and the heat dissipation performance is more excellent.
Provided are a GLP-1/glucagon (GCG) receptor dual-agonist polypeptide compound. The GLP-1/GCG receptor dual-agonist polypeptide compound has the functions of promoting weight reduction and preventing weight gain while lowering blood glucose, reversing insulin resistance, and regulating lipid metabolism. The polypeptide compound has higher agonist activity on a GLP-1 receptor and a GCG receptor than natural ligands for the receptors, and has lower agonist activity on a GIP receptor. The polypeptide compound provided in the present invention has stable chemical properties and low immunogenicity, and is suitable for being used as an active ingredient of drugs for treating metabolic diseases, such as diabetes, obesity, hyperlipidemia, NAFLD, and NASH.
A multicolor light-storing ceramic for fire-protection indication and a preparation method thereof are provided. The preparation method includes: adding a glass based raw material, a light-storing powder, a dispersant and an alumina powder into a granulator, adding water mixed with a pore-forming agent and then mechanically stirring for granulation; adding a plasticizer after the stirring of 4˜8 h, and continuing the stirring for 1˜3 h to thereby obtain a mixture; packing the mixture into a mold and performing tableting; demolding and obtaining a light-storing self-luminous quartz ceramic by drying and firing using a kiln; printing a pattern onto a surface of the ceramic and then curing to obtain a light-storing ceramic for indication sign. Using an industrial waste glass has advantages of low sintering temperature and green environmental protection; dispersed pores and alumina introduced as scattering sources improves light absorption efficiency, fluorescence output phase ratio and light transmission of the ceramic.
C04B 35/14 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxides based on silica
B28B 3/02 - Producing shaped articles from the material by using pressesPresses specially adapted therefor wherein a ram exerts pressure on the material in a moulding spaceRam heads of special form
B28B 3/08 - Producing shaped articles from the material by using pressesPresses specially adapted therefor wherein a ram exerts pressure on the material in a moulding spaceRam heads of special form with two or more rams per mould
B28B 11/24 - Apparatus or processes for treating or working the shaped articles for curing, setting or hardening
B41M 1/34 - Printing on other surfaces than ordinary paper on glass or ceramic surfaces
C04B 35/622 - Forming processesProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products
C04B 35/626 - Preparing or treating the powders individually or as batches
C04B 35/636 - Polysaccharides or derivatives thereof
A preparation method for improving light efficiency and stability of light storing ceramics is provided. Calcium ethanol solution is added into titanium precursor solution firstly and oleic acid dispersant is added, pure water and the light storing powder are subsequently added to obtain a light-storing powder-calcium titanate gel, and dried, crushed and sieved to obtain xerogel powder. Glass matrix material, sieved xerogel powder and another dispersant are placed into a granulator, and directly mechanically stirred and granulated after adding pure water. A plasticizer is added after stirring 4˜8 h, and continuously stirred for 1˜3 h to obtain a mixture, pressing, drying and firing. Calcium titanate is manually introduced to protect the light-storing powder from hydrolysis or high-temperature oxidation. It can also change the propagation path of fluorescence inside ceramics, improve light absorption and fluorescence output efficiency and is conducive to ceramic molding.
C04B 35/465 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxides based on titanium oxides or titanates based on titanates based on alkaline earth metal titanates
C04B 24/38 - Polysaccharides or derivatives thereof
The present disclosure discloses a novel assembled nuclear magnetic resonance (NMR) sample tube and an assembly method thereof. The structure includes a common NMR sample tube, a first open-top screw cap and a second open-top screw cap. The first screw cap is sleeved on the common NMR sample tube, and an open end of the first screw cap is tightly connected to an outer wall of the common NMR sample tube. The second screw cap is in threaded connection with the screw thread on the top of the short tube. A short tube is sleeved on the common NMR sample tube, and the screw thread at the bottom of the short tube is in threaded connection with the first screw cap. A silicone rubber septum is located between the open end of the second screw cap and the screw thread on the top of the short tube.
Disclosed are a light-storage-type multi-phase ceramic material having ultra-high brightness and a preparation method therefor. The method involves homogenizing a long afterglow phosphor powder, a quartz ceramic powder, and a pore-forming agent to formulate a slurry, subjecting same to casting molding and drying, and sintering same to form a multi-phase structure having "pore + light-storage ceramic". There are micropores inside the ceramic material, the pores have a high degree of sphericity and a diameter size in the range of 100-1000 nm, and satisfy conditions under which Mie scattering of fluorescence occurs inside the ceramic, so that the propagation path of the fluorescence is changed and the total reflection effect is weakened. Compared with existing multi-phase light-storage ceramic materials, the front light extraction efficiency is remarkably increased by 10-30%, and the preparation process is simple and rapid, uses a low sintering temperature, and easily achieves batch production.
C04B 35/44 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxides based on aluminates
C04B 35/622 - Forming processesProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products
17.
METHOD FOR INCREASING BOTH LIGHT EFFICIENCY AND STABILITY OF LIGHT STORAGE CERAMIC
Disclosed is a method for increasing both the light efficiency and stability of a light storage ceramic, the method involving first adding an ethanol solution of calcium to a titanium precursor solution, adding oleic acid as a dispersing agent, and subsequently adding pure water and a light storage powder to obtain a light storage powder-calcium titanate gel; drying, comminuting and sieving same to obtain a dry gel powder; placing a glass matrix raw material, the sieved dry gel powder and a dispersing agent into a pelletizer, adding pure water, and then subjecting same to direct mechanical stirring and pelleting; after 4-8 hours of stirring, adding a plasticizer, and continuing to stir same for 1-3 hours to obtain a blend; and tableting same, drying same and firing same in a furnace. By means of the artificial and controllable introduction of calcium titanate as a second phase to coat the light storage powder and form a "core-shell structure", the light storage powder is protected from hydrolysis or high-temperature oxidation. As a plating layer for the light storage powder, calcium titanate can further change the propagation path of fluorescence inside the ceramic and increase the light absorption and fluorescence output efficiency. In addition, the light storage powder with a surface of calcium titanate improves the plasticity of a ceramic paste, thereby facilitating ceramic molding.
C04B 35/465 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxides based on titanium oxides or titanates based on titanates based on alkaline earth metal titanates
18.
MULTICOLOR LIGHT-ACCUMULATING CERAMIC FOR FIRE INDICATION AND PREPARATION METHOD THEREFOR
Disclosed are a multicolor light-storing ceramic for fire indication and a preparation method therefor. The preparation method comprises: placing a glass matrix raw material, long afterglow light-accumulating powder, a dispersant and aluminium oxide powder into a granulator, adding pure water doped with a pore-forming agent, directly and mechanically stirring for pelletizing, stirring for 4 to 8 hours, then adding a plasticizer, continuing to stir for 1 to 3 hours to obtain a mixed material, packing the mixed material into a mold, and tabletting same; then releasing, and feeding same into a kiln for drying and firing to obtain a light-accumulating and self-luminous quartz ceramic; and performing pattern printing on the surface of the ceramic product, and curing to obtain a light-accumulating ceramic which can be used for an indication mark. The present invention uses industrial waste glass as a raw material, has a low sintering temperature, and is environmentally friendly. Introducing dispersive distributed pores and aluminium oxide as scattering sources at the same time further improves the light absorption efficiency and the fluorescence output phase rate of the ceramic. The aluminium oxide phase serving as a scattering source can also serve as a light-transmitting medium, thereby improving the light transmittance of the ceramic and presenting a texture like jade. The method has simple steps and low costs.
C04B 35/14 - Shaped ceramic products characterised by their compositionCeramic compositionsProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products based on oxides based on silica
C04B 35/622 - Forming processesProcessing powders of inorganic compounds preparatory to the manufacturing of ceramic products
C04B 41/85 - Coating or impregnating with inorganic materials
19.
Lifting container power generating device using flexible guidance system
A lifting container power generating device using a flexible guidance system includes a power source section, a power transmission section and an electrical section. The power source section includes a slide recess base electrically connected to a top portion of a flexible lifting container. A body is connected to the slide recess base through a linear bearing. A fixed roller and a sliding roller on the body are symmetrically disposed at two sides of a guide wire rope. Under the combined action of a preloaded spring and a tension spring, the fixed roller and the sliding roller jointly press tightly against the guide wire rope. The power transmission section includes an electromagnetic clutch axially connected to the fixed roller, and an electromagnetic clutch pulley connected to a power generator pulley via a V-belt. The power source section includes an electrical cabinet connected to the electromagnetic clutch, a power generator and a battery of the flexible lifting container. The power generating device provides the battery of the lifting container with power during an operation of the flexible lifting container, solving issues of safety risks caused by current periodical replacement and charging of a battery of the flexible lifting container.
2 leakage event and determining a sensitivity partition, designing different coverage control schemes of monitoring sensor network nodes, or intensively or sparsely arranging sensor monitoring nodes, a coverage network is described and optimally expressed on the basis of Delaunay triangulation. In the method for optimizing sensor network node location in a geological carbon dioxide storage area, the arrangement density of wireless sensor network nodes can be dynamically adjusted according to geological and geographical features of a detection area, and the arrangement optimization of a dynamic monitoring sensor network for coal seam carbon dioxide injection area leakage can be realized. The method reduces node redundancy and communication overheads as much as possible, and has strong network coverage and network connectivity.
A system for clearing a blocked pneumatic transport pipe. A material transport pipe (11) is provided with a pressure measurement system and a counter pressure increasing system sequentially arranged in a material flow direction. The pressure measurement system comprises a pressure measurement pipe (6) and a pressure sensor (6-1). The counter pressure increasing system comprises a counter pressure increasing pipe (9), an electrically-controlled directional control valve (8), a transport flow valve (7), a reverse flow valve (10), a high-pressure air transport pipe (1), and a vacuum suction pipe (3). Three pipe connectors (9-1) and three ring-shaped air cavities (9-2) are arranged at the counter pressure increasing pipe (9). The three ring-shaped air cavities (9-2) are respectively provided with a set of rotational-flow holes (9-3), a set of pressure increasing holes (9-4) and a set of counter-rotational-flow holes (9-5) running towards the inside of the counter pressure increasing pipe (9). The system can increase pressure and prevent blocking of a pipe.
B65G 53/66 - Use of indicator or control devices, e.g. for controlling gas pressure, for controlling proportions of material and gas, for indicating or preventing jamming of material
22.
SYSTEM AND METHOD FOR HIGHLY EFFICIENT REMOVAL OF DUST FROM PNEUMATIC TRANSPORT PIPE
A system for highly efficient removal of dust from a pneumatic transport pipe comprises a pneumatic material transport pipe (10). The pneumatic material transport pipe (10) is provided with a dust measurement device (7) and a misting device (8) connected to a control device and sequentially arranged in a material flow direction. The control device controls, according to a change in a dust amount in the pneumatic material transport pipe (10), the misting device (8) to generate mist in an amount corresponding to the dust amount. The system for highly efficient removal of dust from a pneumatic transport pipe can perform a dust removal operation with respect to a portion of or the entire pipe, prevent material deterioration or blocking of the pipe resulting from an excessive amount of mist, and prevent problems such as locally accumulated heat and dust explosion due to insufficient mist.
A precise pressure increasing system for pneumatic transport comprises a pneumatic material transport pipe (10). The pneumatic material transport pipe (10) is provided with a pressure measurement device (7) and a pressure increasing device (8) sequentially arranged in a material flow direction. The pressure measurement device (7) comprises a pressure measurement pipe (7-4) and a pressure sensor (7-1). The left and right ends of the pressure measurement pipe (7-4) are connected to the pneumatic material transport pipe (10). The pressure sensor (7-1) is arranged above a central portion of the pressure measurement pipe (7-4). The pressure increasing device (8) comprises a pressure increasing pipe (8-5), an electrically-controlled directional control valve (6), a flow meter (5), an electrically-controlled flow valve (4) and a high-pressure air transport pipe (3). The left and right ends of the pressure increasing pipe (8-5) are connected to the pneumatic material transport pipe (10). The pressure increasing pipe (8-5) is provided with three pressure increasing valves. The invention further comprises a data collection device and a data analysis controller which are electrically connected. The system meets a pressure requirement of a pipe while preventing an excessive pressure increment.
Disclosed by the present invention is a carbon nano-material composite structure-based three-dimensional silicon through-hole vertical interconnection method: fabricating silicon holes on a silicon substrate; depositing an insulating layer on a surface of the silicon substrate and an inner wall of the silicon holes; depositing a blocking layer on the insulating layer, and depositing a catalytic metal layer on the blocking layer; etching the catalytic metal layer to form catalytic nano-particles; using the catalytic nano-particles to grow a carbon nano-material composite layer; attaching a dry film on a surface of the carbon nano-material composite layer on the silicon substrate, exposing and developing to form a dry film layer; depositing a seed layer on a bottom surface of the silicon holes and a surface of the dry film layer; filling a conductive material into the silicon holes. The present invention uses the excellent thermal and mechanical performance of a carbon nano-material to solve the heat dissipation problem of a through silicon via (TSV) encapsulation structure that is caused by increased power density as well as the problem of thermal stress mismatch among encapsulation materials, thus improving the thermal conductivity and encapsulation reliability of a 3D-TSV structure.
Disclosed are a multi-drug combined rehabilitation electuary for type 2 diabetes and the use thereof. The electuary is prepared by compounding the following components, in percentages by weight: 45% to 90% of sorbitol, 5% to 50% of betaine or betaine hydrochloride, and 0.01% to 10% of Span 60. The sorbitol of the present invention enables the dissolved fat to form a stable emulsion or ultramicroemulsion, and has a molecular structure similar to that of a glucose molecule, can simulate the glucose molecule to play a targeted localization role, and also has a certain sweetness to improve the taste of the electuary. The betaine/betaine hydrochloride is a biosurfactant for helping to dissolve fat, and also has the function of protecting and nourishing the liver, and improves the insulin utilization efficiency. The Span 60 enables the fat on the surface of a deposition channel to dissolve gradually. The electuary of the present invention enables the fat deposited on the surface of the channel and the semipermeable membrane to form a stable "oil-in-water" emulsion or ultramicroemulsion, so that the deposited fat is excreted from the body via the excretory system after dissolution and the insulin utilization efficiency is improved.
A61K 31/34 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
A61K 31/205 - Amine addition salts of organic acidsInner quaternary ammonium salts, e.g. betaine, carnitine
A61K 31/047 - Hydroxy compounds, e.g. alcoholsSalts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
An automatic handle assembly system for a paint brush, comprising a feeding device (1), a conveying device (2), a handle pushing device (3), a pneumatic system, and a control system; the feeding device (1) is used for transporting a glue filled paint brush head to an entrance of the conveying device (2); the conveying device (2) is used for transporting, pressing, and precisely positioning the paint brush head; the conveying device (2) comprises a machine frame (21), a conveying platform (22), a brush head guiding mechanism (23), a brush head pre-pressing mechanism (24), a pressing and positioning mechanism (25), and a linkage transport mechanism (26); the handle pushing device (3) is used for precisely pushing a paint brush handle into the paint brush head, and the handle pushing device (3) comprises a bracket (31), a mounting platform (32), a handle pushing mechanism (33), a handle storage mechanism (34), a handle pressing mechanism (35), and a shell supporting mechanism (36); the feeding device (1), the conveying device (2), and the handle pushing device (3) are all connected to the pneumatic system and the control system. The system is suitable for application in many types of paint brush handles; having a high degree of automation, easy operations, and accurate assembly, the system effectively improves production efficiency and product quality of paint brushes, while reducing production costs.
A lifting container power generating device (20) using a flexible guidance system comprises a power source section, a power transmission section and an electrical section. The power source section comprises a slide recess base (11) electrically connected to a top portion of a flexible lifting container (18). A body (6) is connected to the slide recess base (11) through a linear bearing. A fixed roller (10) and a sliding roller (7) on the body (6) are symmetrically disposed at two sides of a guide wire rope (8). Under the combined action of a preloaded spring (19) and a tension spring (5), the fixed roller (10) and the sliding roller (7) jointly press tightly against the guide wire rope (8). The power transmission section comprises an electromagnetic clutch (4) axially connected to the fixed roller (10), and an electromagnetic clutch pulley (3) connected to a power generator pulley (1) via a V-belt (2). The power source section comprises an electrical cabinet (16) connected to the electromagnetic clutch (4), a power generator (13) and a battery of the flexible lifting container (18). The power generating device provides the battery of the lifting container with power during an operation of the flexible lifting container (18), solving issues of safety risks caused by current periodical replacement and charging of a battery of the flexible lifting container (18).
H02J 7/32 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from a charging set comprising a non-electric prime mover
F03G 7/00 - Mechanical-power-producing mechanisms, not otherwise provided for or using energy sources not otherwise provided for
28.
SERIES OF FLUORINE-CONTAINING CARBAZOLE COMPOUNDS, PREPARATION METHOD AND USE THEREOF
Disclosed in the present invention are a series of fluorine-containing carbazole compounds, preparation method and use thereof, which belong to the field of organic chemistry, pharmaceutical chemistry and drug intermediates. In the invention, the series of fluorine-containing carbazole compounds are obtained by catalyzing C-C bond coupling reaction, and the structural formula thereof is shown in Formula 1. It is shown in the in vitro experiments of the compounds represented by Formula 1 that some of the compounds of the present invention have the activity of inhibiting the "super bacteria" strains such as Escherichia coli and Klebsiella pneumoniae with NDM-1 drug-resistant gene and methicillin resistant Staphylococcus aureus (MRSA), etc. The present invention provides the lead compound for developing an antimicrobial agent with a new structure. The synthetic method thereof is simple and the production cost is low, thereby having high development value and application prospect.
C07D 209/88 - CarbazolesHydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
C07D 209/86 - CarbazolesHydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
A61K 31/403 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
CATALYTIC SYSTEM AND METHOD FOR PREPARING ETHYLENE CARBONATE DERIVATIVE BY REACTION OF CARBON DIOXIDE AND ETHYLENE OXIDE DERIVATIVE UNDER EXTREMELY MILD CONDITIONS
An imidazole ionic liquid-ZnX2/base catalytic system and a method for catalytic preparation of an ethylene carbonate derivative with same. The catalytic system is composed of three ingredients, an imidazole ionic liquid, ZnX2 and a base and can catalyze a cycloaddition reaction of carbon dioxide and an ethylene oxide derivative under conditions of 0.5-1 atm., 15°C-35°C and a green solvent. The amounts of ZnX2 and the base are both 0.5%-5% of the molar amount of the ethylene oxide derivative, and the amount of the imidazole ionic liquid is 1-3 times the molar amount of the ethylene oxide derivative. The synthetic method has the characteristics of strictly mild reaction conditions, high catalytic activity, a single product, a high reaction yield, a reusable catalyst, a simple product purification operation and the like.
B01J 31/26 - Catalysts comprising hydrides, coordination complexes or organic compounds containing in addition, inorganic metal compounds not provided for in groups
C07D 407/12 - Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a chain containing hetero atoms as chain links
C07D 317/46 - Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
Disclosed is a novel multifunctional combined bathroom, which comprises an upright column (1), a elevatable bathtub (2), a rotatable sink (3), a rotatable armrest (4), a rotatable bath chair (5) and a rotatable toilet (6), wherein the rotatable bath chair (5) can be used as a toilet lid, the elevatable bathtub (2) can be lifted upward and downward along the upright column, the rotatable sink (3), the rotatable armrest (4), the rotatable bath chair (5) and the rotatable toilet (6) can be adjusted upward and downward along the upright column and can also rotate in front of or behind the upright column (1) using the upright column (1) as a shaft. Both the length and width of the rotatable armrest (4) can be adjusted. Each of the bathroom products therein can be rotated and adjusted upward and downward, which not only is suitable for people who have difficulty in moving, but also improves the spacial utilization rate.
A vertical cylinder sleeve piston ring friction-wear test device comprises a motor (1) and an oil supply pipe (2), and further comprises a friction force test device (3), a raised holding jaw (5), a piston assembly (6), a positive pressure test device (7), a chuck base (8), an oil storage tank (9) and a heating device (10). A cylinder sleeve to be tested is cut into three test pieces (4) respectively mounted on the holding jaws (5) of a centered electrically powered three-jaw chuck, the raised holding jaws (5) clamping to apply a radial load. A load change between cylinder sleeve piston rings is simulated to test friction and lubricity performance thereof, so as to guide the pairing and selection of a cylinder sleeve piston ring friction pair model.
Disclosed are an auto-brake device and method for a winch for a vehicle. The device comprises a shaft guard (1), a brake shaft (2) and a spiral clutch mechanism, wherein the spiral clutch mechanism comprises a cone brake component (6), a torsion spring (5) and a lug disk (4). A single-row tapered roller bearing (8) is arranged on the brake shaft (2), a brake cone sleeve (7) wedged together with the cone brake component (6) is arranged on the single-row tapered roller bearing (8), and a spline engaged with an inner tooth ring of a winch drum is arranged at the outer edge of the brake cone sleeve (7). When an electric motor drives the shaft to rotate, the shaft guard (1) rotates clockwise, to toggle the cone brake component (6) to rotate, and extrude the torsion spring (5) to move leftwards, thereby separating the cone brake component (6) from the brake cone sleeve (7); and when the electric motor drives the shaft to stop rotating, the cone brake component (6) rotates clockwise to reset under the action of the torsion spring (5), the cone brake component (6) moves rightwards to wedge and enclasp together with the brake cone sleeve (7) rotating at low speed, and the brake shaft (2) stops rotating, thereby playing a role of braking. The device has the advantages of a simple structure, easy operation, quick assembling, high braking reliability, low operating temperature and a long service life.
patents
