A method (S100) of obtaining training data for an existing artificial intelligence, Al, model to process data for diagnostics purposes, the method comprises the steps of: providing (S20) an input dataset comprising of a first set of data including data representative of a sampling device and a second set of data including time domain data representative of a patient sample; and processing (S30) the input dataset to obtain a transformed dataset to provide as training dataset to the existing Al model.
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
G01N 33/497 - Physical analysis of biological material of gaseous biological material, e.g. breath
A61B 5/08 - Measuring devices for evaluating the respiratory organs
A mouthpiece is disclosed through which a user inhales and exhales when providing an exhaled breath sample. The mouthpiece includes a mouth-engaging element about which a user places their mouth when using the mouthpiece and also a housing having a housing wall. The housing wall defines a first aperture through the housing wall, the first aperture being linked by a conduit defining a first fluid flow path to the mouth-engaging element. Interposed therebetween is a first directional valve, allowing air into the mouthpiece from atmosphere. A second conduit is provided, defining a second fluid flow path from the mouth-engaging element, and directing exhaled air out of a second aperture of the mouthpiece. The second conduit houses a second directional valve housed within the second fluid flow path.
Aspects relate to a system for collecting condensate from exhaled breath and performing a test to analyze presence of a virus in the collected condensate. The system may include a disposable for collecting the condensate and a reusable electronic device for performing the test. In some embodiments, a user may exhale into the disposable and the electronic device provides the user with a result of the test indicating whether the user is infected with the virus. The virus detected may be severe acute respiratory syndrome coronavims 2 (SARS-CoV-2), the virus that causes COVID-19 (coronavims disease 2019). Additional aspects relate to determining a fill state of a sensor associated with collection of the exhaled breath condensate, calibration and function testing of the system used for determining a presence of a virus in the exhaled breath condensate and reading identifying information stored on the disposable used for collecting the exhaled breath condensate.
The invention as disclosed herein provides a breath-condensate analysis cartridge suitable for incorporation into an exhalation device. The cartridge comprises a condensation zone to receive exhaled breath, the condensation zone having a peripheral region. An analysis chamber is included in which a condensed breath sample is analysed. The surface of the condensation zone acts. to create a fluid flow path in the peripheral region. A fluid flow path through the peripheral region links the condensation zone to the analysis chamber. A lip at least partially covers the peripheral region, the lip co-operating with the condensation zone to form a capillary to control fluid flow.
A61B 5/08 - Measuring devices for evaluating the respiratory organs
A61B 5/097 - Devices for facilitating collection of breath or for directing breath into or through measuring devices
A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
A mouthpiece is disclosed through which a user inhales and exhales when providing an exhaled breath sample. The mouthpiece includes a mouth-engaging element about which a user places their mouth when using the mouthpiece and also a housing having a housing wall. The housing wall defines a first aperture through the housing wall, the first aperture being linked by a conduit defining a first fluid flow path to the mouth-engaging element. Interposed therebetween is a first directional valve, allowing air into the mouthpiece from atmosphere. A second conduit is provided, defining a second fluid flow path from the mouth-engaging element, and directing exhaled air out of a second aperture of the mouthpiece. The second conduit houses a second directional valve housed within the second fluid flow path.
A mouthpiece is disclosed through which a user inhales and exhales when providing an exhaled breath sample. The mouthpiece includes a mouth-engaging element about which a user places their mouth when using the mouthpiece and also a housing having a housing wall. The housing wall defines a first aperture through the housing wall, the first aperture being linked by a conduit defining a first fluid flow path to the mouth-engaging element. Interposed therebetween is a first directional valve, allowing air into the mouthpiece from atmosphere. A second conduit is provided, defining a second fluid flow path from the mouth-engaging element, and directing exhaled air out of a second aperture of the mouthpiece. The second conduit houses a second directional valve housed within the second fluid flow path.
The device as disclosed herein is to measure breath humidity, the device comprises an inlet fluidly connected at a first end of a tubular body, said tubular body defining an inner tube volume. The device further comprises a condenser plate, fluidly connected to the second end of the tubular body to receive exhaled breath. A partition wall intermediate the first and second ends divides the inner tube volume into first and second chambers, the second chamber providing fluid access to the condenser plate. The wall has a one-way valve therethrough allowing breath from the first to the second chamber. The device further comprises one or more apertures in the tubular body wall of the first chamber, the or each aperture fluidly linking a sensor to the first chamber, and a relative humidity sensor fluidly linked to the second chamber.
The invention as disclosed herein provides a breath-condensate analysis cartridge suitable for incorporation into an exhalation device. The cartridge comprises a condensation zone to receive exhaled breath, the condensation zone having a peripheral region. An analysis chamber is included in which a condensed breath sample is analysed. The surface of the condensation zone acts. to create a fluid flow path in the peripheral region. A fluid flow path through the peripheral region links the condensation zone to the analysis chamber. A lip at least partially covers the peripheral region, the lip co-operating with the condensation zone to form a capillary to control fluid flow.
The invention as disclosed herein provides a breath-condensate analysis cartridge suitable for incorporation into an exhalation device. The cartridge comprises a condensation zone to receive exhaled breath, the condensation zone having a peripheral region. An analysis chamber is included in which a condensed breath sample is analysed. The surface of the condensation zone acts. to create a fluid flow path in the peripheral region. A fluid flow path through the peripheral region links the condensation zone to the analysis chamber. A lip at least partially covers the peripheral region, the lip co-operating with the condensation zone to form a capillary to control fluid flow.
The device as disclosed herein is to measure breath humidity, the device comprises an inlet fluidly connected at a first end of a tubular body, said tubular body defining an inner tube volume. The device further comprises a condenser plate, fluidly connected to the second end of the tubular body to receive exhaled breath. A partition wall intermediate the first and second ends divides the inner tube volume into first and second chambers, the second chamber providing fluid access to the condenser plate. The wall has a one-way valve therethrough allowing breath from the first to the second chamber. The device further comprises one or more apertures in the tubular body wall of the first chamber, the or each aperture fluidly linking a sensor to the first chamber, and a relative humidity sensor fluidly linked to the second chamber.
The device as disclosed herein is to measure breath humidity, the device comprises an inlet fluidly connected at a first end of a tubular body, said tubular body defining an inner tube volume. The device further comprises a condenser plate, fluidly connected to the second end of the tubular body to receive exhaled breath. A partition wall intermediate the first and second ends divides the inner tube volume into first and second chambers, the second chamber providing fluid access to the condenser plate. The wall has a one-way valve therethrough allowing breath from the first to the second chamber. The device further comprises one or more apertures in the tubular body wall of the first chamber, the or each aperture fluidly linking a sensor to the first chamber, and a relative humidity sensor fluidly linked to the second chamber.
A cartridge device (10) for collecting and analysing a breath condensate is disclosed. The device (10) comprises a condensation zone (12) to condense exhaled breath from a subject and cooling means operably connected to the condensation zone (12). The device includes further discrete regions (13) for detection of analyte and measurement of analyte. The condensation zone (12) has a fluid exit connecting the condensation zone (12) to the discrete regions (13).
A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
G01N 25/14 - Investigating or analysing materials by the use of thermal means by using distillation, extraction, sublimation, condensation, freezing, or crystallisation
Medical apparatus; medical hand tools; medical instruments; medical devices; medical analysis apparatus; medical analysis instruments; medical analysis devices; medical diagnostic apparatus; medical diagnostic instruments; medical diagnostic devices; medical testing apparatus; medical testing instruments; medical testing devices; medical therapy apparatus; medical therapy instruments; medical therapy devices; veterinary apparatus; veterinary hand tools; veterinary instruments; veterinary devices; veterinary analysis apparatus; veterinary analysis instruments; veterinary analysis devices; veterinary diagnostic apparatus; veterinary diagnostic instruments; veterinary diagnostic devices; veterinary testing apparatus; veterinary testing instruments; veterinary testing devices; veterinary therapy apparatus; veterinary therapy instruments; veterinary therapy devices; examination equipment for medical purposes; examination equipment for veterinary purposes; monitoring equipment for medical purposes; monitoring equipment for veterinary purposes; detectors for medical applications; detectors for veterinary applications; diagnostic kits; physiotherapy equipment; probes for medical purposes; probes for veterinary purposes; rehabilitation equipment; tools for medical diagnostics; tools for veterinary diagnostics; parts and fittings for the aforesaid goods.
An analyser for collecting and analysing a breath condensate is disclosed. The analyser comprises a housing and a cartridge device (10). The device comprises a condensation zone (12) to condense exhaled breath from a subject and cooling means operably connected to the condensation zone (12). The device includes further discrete regions (13) for detection of analyte and measurement of analyte. The condensation zone (12) has a fluid exit connecting the condensation zone (12) to the discrete regions (13). The analyser includes a mouthpiece which is provided with a plurality of chambers configured to cause a change of 90° in the direction of the exhaled breath in order to trap saliva aerosols.
A cartridge device (10) for collecting and analysing a breath condensate is disclosed. The device (10) comprises a condensation zone (12) to condense exhaled breath from a subject and cooling means operably connected to the condensation zone (12). The device includes further discrete regions (13) for detection of analyte and measurement of analyte. The condensation zone (12) has a fluid exit connecting the condensation zone (12) to the discrete regions (13).
A cartridge device (10) for collecting and analysing a breath condensate is disclosed. The device (10) comprises a condensation zone (12) to condense exhaled breath from a subject and cooling means operably connected to the condensation zone (12). The device includes further discrete regions (13) for detection of analyte and measurement of analyte. The condensation zone (12) has a fluid exit connecting the condensation zone (12) to the discrete regions (13). [Figure 12b]
An analyser for collecting and analysing a breath condensate is disclosed. The analyser comprises a housing and a cartridge device (10). The device comprises a condensation zone (12) to condense exhaled breath from a subject and cooling means operably connected to the condensation zone (12). The device includes further discrete regions (13) for detection of analyte and measurement of analyte. The condensation zone (12) has a fluid exit connecting the condensation zone (12) to the discrete regions (13). The analyser includes a mouthpiece which is provided with a plurality of chambers configured to cause a change of 90° in the direction of the exhaled breath in order to trap saliva aerosols.
A breath condensate collector (10) comprising a chamber having a breath inlet port (14) and an outlet port (16); a sample collector, adapted to receive breath from the chamber outlet and having air exhaust means; cooling means (112) to promote in use condensation of vapor from breath entering the sample collector and where collector comprises a partially lidded dish (110).
Medical, and veterinary apparatus and instruments, apparatus
for the alleviation of breathing difficulties; apparatus for
use in collecting exhaled breath; apparatus for use in
analysing exhaled breath; apparatus for use in medical
analysis; apparatus for use in veterinary analysis; medical
apparatus for use in the investigation of metabolic
disorders;
body rehabilitation apparatus for medical
purposes; breath condensate or gas analysers for medical
diagnostics; breath condensate or gas analysers for
veterinary diagnostics; cases fitted for medical or
veterinary instruments; diagnostic, examination and
monitoring equipment for medical use; diagnostic apparatus
for medical purposes; diagnostic apparatus for veterinary
purposes; medical diagnostic instruments sold in the form of
kits; medical testing apparatus and instruments for the
detection of respiratory disorders sold as kits; electro
medical diagnostic apparatus and instruments;
electrophysiology diagnostic apparatus and instruments;
medical apparatus for assisting breathing; medical apparatus
for controlling pulmonary gas exchange parameters; medical
apparatus for the treatment of breathing difficulties;
pulmonary diagnostic apparatus and instrumentation;
pulmonary function testing apparatus and instrumentation;
respiratory apparatus and instrumentation; respiratory
monitors (medical and veterinary); respiratory therapy
apparatus and instrumentation; testing apparatus for medical
purposes; testing probes for diagnostic purposes; tools for
medical diagnostics; tools for veterinary diagnostics;
veterinary apparatus for assisting breathing; veterinary
apparatus for controlling pulmonary gas exchange parameters;
veterinary apparatus for the treatment of breathing
difficulties; parts and fittings for the aforesaid goods.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
(1) Medical apparatus and instruments, namely, apparatus for the alleviation of breathing difficulties, namely, handheld diagnostic apparatus capable of analysing exhalate and breath condensates with inbuilt software recommending what crisis treatment necessary to alleviate breathing difficulties being experienced by a patient; apparatus for use in collecting exhaled breath, namely, exhaled breath sample collection, analysis and reader instrumentation housed within a portable handheld unit and operating software sold therewith as a unit for use in the diagnosis of COPD crisis, COPD exacerbations, asthma events, pulmonary crisis events and the identification of condensates signalling the occurrence of a medical crisis; apparatus for use in analysing exhaled breath, namely, exhaled breath analysis and reader instrumentation housed within a portable handheld unit and operating software sold therewith as a unit for use in the diagnosis of COPD crisis, COPD exacerbations, asthma events, pulmonary crisis events and the identification of condensates signaling the occurrence of a medical crisis; apparatus for use in medical analysis, namely, computerized medical recording and analysis instrumentation for the diagnosis and treatment of respiratory conditions for medical use; apparatus for use in the investigation of metabolic disorders, namely, computerized recording and analysis instrumentation for the monitoring of metabolic functions; body rehabilitation apparatus for medical purposes, namely, medical apparatus for evaluating the need for the introduction of therapeutic agents for patients receiving medical rehabilitation, namely medical apparatus for diagnosing the need for the inhalation of pharmaceutical preparations and therapeutic agents; body rehabilitation apparatus for medical purposes, namely, medical apparatus for introducing therapeutic agents to patients receiving medical rehabilitation, namely medical apparatus for facilitating the inhalation of pharmaceutical preparations and therapeutic agents; breath condensate and gas analysers for medical diagnostics; diagnostic, examination and monitoring equipment, namely, medical instrumentation for monitoring heart rate, pulse oxymetary, breathing, gas analysis and respiratory events; medical instrumentation for monitoring heart rate, pulse oxymetary, breathing, gas analysis and respiratory events and software sold therewith as a portable handheld unit; diagnostic apparatus for medical purposes, namely, instrumentation used in implementing medical diagnostic tests in relation to breathing, gas analysis and respiratory events; medical diagnostic kits, namely, medical diagnostic instruments sold in the form of kits comprised of breath and exhalate condensate specimen collection kit and instructions, all for medical use by patients, their care givers and medical professionals in relation to breathing, gas analysis and respiratory events; diagnostic test kits for the detection of respiratory disorders; electro medical diagnostic apparatus and instruments for use in the diagnosis of pulmonary or respiratory inflammation, namely, instrumentation used in implementing medical diagnostic tests in relation to breathing, gas analysis and respiratory events; electrophysiology diagnostic apparatus and instruments for use in the diagnosis of pulmonary or respiratory inflammation; medical apparatus for controlling pulmonary gas exchange parameters, namely, computer displays, and computer monitors and controllers therefor used in direct association with medical diagnosis apparatus during the process of diagnosis of a condition in an individual; medical apparatus for the treatment of breathing difficulties, namely, computer displays, and computer monitors and controllers therefor used in direct association with medical diagnosis apparatus during the process of diagnosis of a condition in an individual; pulmonary diagnostic apparatus and instrumentation, namely, diagnostic instrumentation used for the detection of breathing anomalies, pulmonary function, pulmonary dysfunction and respiratory events; pulmonary function testing apparatus and instrumentation, namely, handheld breathing testing machines, handheld pulmonary function and pulmonary dysfunction testing machines; respiratory apparatus and instrumentation, namely, portable medical devices, namely, patient monitors and patient sensors for monitoring respiratory events; respiratory monitors for medical use; respiratory therapy apparatus and instrumentation, namely, medical instrumentation for diagnosing respiratory conditions; tools for medical diagnostics, namely, portable medical instrument for pulmonary and respiratory diagnostics.
Medical apparatus and instruments in the nature of apparatus for the alleviation of breathing difficulties, namely, handheld diagnostic apparatus capable of analyzing exhalate and breath condensates with inbuilt software recommending what crisis treatment necessary to alleviate breathing difficulties being experienced by a patient; apparatus for use in collecting exhaled breath, namely, exhaled breath sample collection, analysis and reader instrumentation housed within a portable handheld unit and operating software sold therewith as a unit for use in the diagnosis of COPD crisis, COPD exacerbations, asthma events, pulmonary crisis events and the identification of condensates signaling the occurrence of a medical crisis; apparatus for use in analysing exhaled breath; apparatus for use in medical analysis, namely, computerized recording and analysis instrumentation for the diagnosis and treatment of respiratory conditions for medical use; medical apparatus for use in the investigation of metabolic disorders, namely, computerized recording and analysis instrumentation for the monitoring of metabolic functions; body rehabilitation apparatus for medical purposes; breath condensate and gas analysers for medical diagnostics; cases fitted for medical instruments; diagnostic apparatus for medical purposes, namely, instrumentation for monitoring heart rate, pulse oxymetary, breathing, gas analysis and respiratory events; [ medical instrumentation for monitoring heart rate, pulse oxymetary, breathing, gas analysis and respiratory events and software sold therewith as a portable handheld unit for medical use; medical diagnostic instruments sold in the form of kits comprised of breath and exhalate condensate specimen collection and identification kit and instructions, all for medical use by patients, their care givers and medical professionals in relation to breathing, gas analysis and respiratory events; ] medical testing apparatus and instruments for the detection of respiratory disorders sold as kits; medical apparatus for controlling pulmonary gas exchange parameters; medical apparatus for assisting breathing, namely, patient breathing system comprising artificial respiration apparatus for medical use; pulmonary diagnostic apparatus and instrumentation, namely, diagnostic instrumentation used for the detection of breathing anomalies, pulmonary function, pulmonary dysfunction and respiratory events for medical use; pulmonary function testing apparatus and instrumentation, namely, handheld breathing testing machines, handheld pulmonary function and pulmonary dysfunction testing machines for medical use; respiratory apparatus and instrumentation, namely, hand-held patient respiratory analysis equipment, and medical devices, namely, patient monitors and patient sensors for monitoring respiratory events; respiratory monitors for medical use; respiratory therapy apparatus and instrumentation, namely, medical instrumentation for diagnosing respiratory conditions, medical instrumentation for treating respiratory conditions; Probes for medical purposes, excluding probes used for blood glucose monitoring or diabetes care; probes for diagnostic purposes, excluding probes used for blood glucose monitoring or diabetes care; tools for medical diagnostics, namely, diagnostic instrumentation and software sold therewith as a handheld portable unit for medical use, excluding diagnostic instrumentation and software used for blood glucose monitoring or diabetes care; replacement parts and fittings for the aforesaid goods
