The present disclosure relates to using 2,2,6,6-tetramethyl-4-piperidone (TMPD) as a reactant in at least one chemical reaction for making a reaction-product compound that comprises at least one cyclic N-halamine precursor group and at least one cationic center, and optionally a coating incorporation group. The present disclosure also relates to using TMPD as a reactant in at least one chemical reaction for making: (a) an intermediate compound that comprises at least one cyclic N-halamine precursor group and at least one coating incorporation group, (b) an intermediate compound that comprises at least one cyclic N-halamine precursor group and at least one cationic center, or (c) an intermediate compound that comprises at least one cyclic N-halamine precursor group, at least one coating incorporation group, and at least one cationic center. The compounds disclosed herein may have biocidal activity, and/or they may have increased biocidal activity following one or more chemical-modification reactions.
A01N 37/28 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing the group —CO—N, e.g. carboxylic acid amides or imidesThio-analogues thereof containing the group Thio-analogues thereof
A01P 1/00 - DisinfectantsAntimicrobial compounds or mixtures thereof
C07D 211/58 - Nitrogen atoms attached in position 4
C07D 401/04 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring- member bond
Some embodiments of the present disclosure relate to polymerizable compounds that comprise biocidal activity and/or the potential for increased biocidal activity and that comprise at least one hydrophobic portion and at least one hydrophilic portion. Together the hydrophobic portion and the hydrophilic portion of the compounds may provide the polymerizable compounds with one or more surfactant-like properties. The polymerizable compounds can be incorporated into polymer coating formulations. The polymer coating formulations can be used to coat one or more surfaces of a substrate. The coating formulation can provide biocidal activity and/or the potential for increased biocidal activity to the coated substrate-surface.
The present disclosure describes monomeric compounds and polymeric compounds that comprise at least one of the monomeric compounds and compositions that can be included in a coating composition for coating a substrate. The coated substrate may have biocidal activity or the potential for increased biocidal activity. The potential for increased biocidal activity may be realized by exposing the coated substrate to one or more further agents, such as one or more halogens. The monomer compound comprises (i) one or more cationic centers, (ii) an N-halamine precursor group, and (iii) at least one coating-incorporation group (CIG). The CIG bonds with another component within the coating composition or alternatively the CIG may bond with a component of the substrate. The CIG of the composition may incorporate the monomer into the coating composition, may incorporate the coating composition onto the substrate, or the CIG may perform both functions.
C07F 9/655 - Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
C09D 5/14 - Paints containing biocides, e.g. fungicides, insecticides or pesticides
4.
USE OF COMPOUNDS FOR MAKING PRODUCTS WITH AT LEAST ONE N-HALAMINE PRECURSOR GROUP AND AT LEAST ONE CATIONIC CENTER
The present disclosure relates to using a compound as a reactant in one or more chemical reactions for making intermediate compounds or reaction-product compounds that includes at least one cyclic N-halamine precursor group and at least one cationic center. The compound has the general formula (1): Wherein Z is either N or Y and when Z is N then R1 and R2 are each independently selected from a group of methyl, ethyl or n-propyl. When Z is Y then R1 and R2 are both nil and Y is selected from Cl, Br and I. The reaction-product compound may have biocidal activity and/or it may have increased biocidal activity following one or more chemical-modification reactions.
Embodiments of the present disclosure relate to compounds that have one, two or more function groups, where the functional groups may be selected from a group consisting of a piperidine, a hydantoin, a quaternary ammonium cation or combinations thereof. The compounds may have biocidal activity and the compounds may subsequently be chemically modified to enhance or provide biocidal activity. The chemical modification may be performed in situ and repeated once or multiple times to extend the time-frame over which the compounds have the desired biocidal activity. The functional groups may be physically separated from one another by other atoms within the compound and this physical separation may provide a desired compound- stability and influence the compound's biocidal activity. The compounds disclosed herein may form part or all of a liquid disinfectant.
C07D 211/58 - Nitrogen atoms attached in position 4
A01N 43/40 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
A01N 57/34 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-halogen bondsPhosphonium salts
A01P 1/00 - DisinfectantsAntimicrobial compounds or mixtures thereof
C07D 211/46 - Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
C07D 211/72 - Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
C07D 233/74 - Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
C07D 401/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
6.
MONOMERS, POLYMERS AND COATING FORMULATIONS THAT COMPRISE AT LEAST ONE N-HALAMINE PRECURSOR, A CATIONIC CENTER AND A COATING INCORPORATION GROUP
A modified surface with at least one cationic center and at least one compound. The surface can be modified by various methods. The result of these methods is that the cationic center and the compound are connected to the modified surface. The cationic center and the compound are connected to the modified surface so that both of the cationic center and the compound are available upon the modified surface to react with other chemicals or microorganisms that come into contact with or near to the modified surface. The availability of the cationic center and the compound cause the modified surface to have a functionality that it would not otherwise have. The number of molecules of the cationic center relative to the number of molecules of the at least one compound may influence the functionality of the modified surface.
A modified surface with at least one cationic center and at least one compound. The surface can be modified by various methods. The result of these methods is that the cationic center and the compound are connected to the modified surface. The cationic center and the compound are connected to the modified surface so that both of the cationic center and the compound are available upon the modified surface to react with other chemicals or microorganisms that come into contact with or near to the modified surface. The availability of the cationic center and the compound cause the modified surface to have a functionality that it would not otherwise have. The number of molecules of the cationic center relative to the number of molecules of the at least one compound may influence the functionality of the modified surface.
The present disclosure relates to a compound that has biocidal activity or is a precursor of a compound with biocidal activity. The compound comprises an N-halamine precursor, at least one quaternary ammonium and at least one coating-incorporation group (CIG). In some embodiments of the present disclosure, the compound may be incorporated into a coating formulation. The coating formulation comprises the compound and at least one further component. In some embodiments of the present disclosure, the CIG reacts with the further component of the coating formulation to incorporate the compound into the coating formulation. In some embodiments, the coating formulation comprises a polymer. In some embodiments, the CIG of the compound reacts with the further component to incorporate the compound into the polymer of the coating formulation. The coating formulation may be used to coat a substrate. The coated substrate may demonstrate biocidal activity or the potential for increased biocidal activity.
C07D 211/58 - Nitrogen atoms attached in position 4
C07C 275/50 - Y being a hydrogen or an acyclic carbon atom
C07D 211/46 - Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
C07D 233/64 - Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
