A process and sensor system with particular control of polarization of the interrogating light beams useful for determining a concentration of a targeted molecule M (such as glucose) within a given time period in a liquid sampling matrix through use of a Direct Infrared Laser Absorption Spectroscopy Technique.
G01N 21/3577 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing liquids, e.g. polluted water
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A controller and a distal sensor module are used to emit optical emissions to a liquid sample being tested in a human body and detect desired optical data which the controller uses to electronically calculate a concentration measurement of a targeted analyte (e.g., glucose). The distal sensor module is held in place by a retention mechanism while a clamping system applies clamping pressure to the liquid sample during a test period to maintain a specified sample height of the liquid sample. An optical cable is intermediate the controller and the distal sensor module and is pluggably connected to the controller. Continuous monitoring of the analyte is possible without disconnecting the controller from the optical cable or the distal sensor module from the patient while clamping pressure on the test sample is reduced outside of the test period.
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
3.
Reflective depth interrogation for analyte measurement in liquids
An absorption spectroscopy process uses a single radiation beam with two or more pulsed beams (including at least a signal beam and a reference beam) that are passed into a liquid sample to a variable effective depth and then reflected out of the liquid sample where it is detected and processed to obtain a value over a preselected time. As values are determined for multiple effective depths, a sampling dataset is obtained which is used to calculate a concentration level of a targeted particle in the liquid sample by use of calibration dataset obtained from use of known samples.
G01N 33/487 - Physical analysis of biological material of liquid biological material
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
G01N 21/35 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
G01N 21/3577 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing liquids, e.g. polluted water
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
Increased precision for liquid absorption spectroscopy, especially for in vivo samples of human analytes, is obtained by varying the signal or signal and interference central wavelengths when the temperature of the sample site varies beyond a selected threshold used for determining standardized signal or signal and interference central wavelengths. The amount of variance for a central wavelength of the signal beam which includes 1,150 nm is approximately 2 nm or less.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
G01N 15/06 - Investigating concentration of particle suspensions
G01N 33/487 - Physical analysis of biological material of liquid biological material
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
G01N 21/3577 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing liquids, e.g. polluted water
The concentration of a targeted molecule (such as glucose) in a liquid medium having at least one interfering molecule coexisting with the targeted molecule is detected by use of NDIR and a sampling technique in which an imposed location of a pulse beam from a signal source, an interference source and a reference source is varied over a plurality of sites of a sampling area.
G01N 21/3577 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing liquids, e.g. polluted water
G01N 33/49 - Physical analysis of biological material of liquid biological material blood
6.
Enhanced optical data capture using NDIR for liquids
The concentration of a targeted molecule (such as glucose) in a liquid medium having at least one interfering molecule coexisting with the targeted molecule is detected by use of NDIR and a sampling technique in which an imposed location of a pulse beam from a signal source, an interference source and a reference source is varied over a plurality of sites of a sampling area.
G01N 33/49 - Physical analysis of biological material of liquid biological material blood
G01N 21/35 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
G01N 21/3577 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing liquids, e.g. polluted water
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
7.
Enhanced optical data capture using NDIR for liquids
The concentration of a targeted molecule (such as glucose) in a liquid medium having at least one interfering molecule coexisting with the targeted molecule is detected by use of NDIR and a sampling technique in which an imposed location of a pulse beam from a signal source, an interference source and a reference source is varied over a plurality of sites of a sampling area.
G01N 33/49 - Physical analysis of biological material of liquid biological material blood
G01N 21/35 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
G01N 21/27 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection
G01N 21/3577 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing liquids, e.g. polluted water
G in the liquid sample. This value can further be used to adjust the calibration curve via a parameter linking the transmittances measured at the signal and interference wavelength channels in order to assure its validity.
G01N 33/49 - Physical analysis of biological material of liquid biological material blood
G01N 21/35 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
G01N 21/27 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection
G01N 21/3577 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing liquids, e.g. polluted water
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
A glucose sensor measures glucose molecules in vivo through use of NDIR in which scattering noise is reduced and Absorption Interference Noise (AIN) is suppressed with a reflection technique. Electronics are used to provide an output of glucose concentration glucose in a liquid sampling matrix after it has been determined that a calibration curve is valid after signal processing is used to obtain average ratio values for reflected signal/reference channels and interference/reference channel obtained after a pulsed beam from signal, interference and reference sources is directed at an inclined angle to a normal of a spot of the liquid sampling matrix. The signal, interference and reference sources are each pulsed at a preselected frequency of at least N Hz which is sufficiently fast so that a given molecule of glucose or interfering molecule will not pass in and out of the liquid sampling matrix within the preselected frequency.
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
A glucose sensor measures glucose molecules in vivo through use of NDIR in which scattering noise is reduced and Absorption Interference Noise (AIN) is suppressed with a reflection technique. Electronics are used to provide an output of glucose concentration glucose in a liquid sampling matrix after it has been determined that a calibration curve is valid after signal processing is used to obtain average ratio values for reflected signal/reference channels and interference/reference channel obtained after a pulsed beam from signal, interference and reference sources is directed at an inclined angle to a normal of a spot of the liquid sampling matrix. The signal, interference and reference sources are each pulsed at a preselected frequency of at least N Hz which is sufficiently fast so that a given molecule of glucose or interfering molecule will not pass in and out of the liquid sampling matrix within the preselected frequency.
G01N 21/35 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
G01N 33/49 - Physical analysis of biological material of liquid biological material blood
G01N 21/3504 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing gases, e.g. multi-gas analysis
G01N 21/3504 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing gases, e.g. multi-gas analysis
13.
Reduction of scattering noise when using NDIR with a liquid sample
A concentration of glucose in a blood sample is determined through use of a signal channel output/reference channel ratio obtained by use of an NDIR absorption technique in which scattering noise attributable to the liquid phase is reduced by alternately and successively pulsing infrared radiation from signal and reference sources which are multiplexed and collimated into a pulsed beam directed through the sample space containing the liquid phase and the pulse frequency is sufficiently fast so that a given molecule of glucose will not pass in and out of the sample space within the pulse frequency.
G01N 33/49 - Physical analysis of biological material of liquid biological material blood
G01N 21/3504 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing gases, e.g. multi-gas analysis
14.
Reduction of scattering noise when using NDIR with a liquid sample
A concentration of a chosen molecule in a liquid phase in a sample space is determined through use of a signal channel output/reference channel ratio obtained by use of an NDIR absorption technique in which scattering noise attributable to the liquid phase is reduced by alternately and successively pulsing infrared radiation from signal and reference sources which are multiplexed and collimated into a pulsed beam directed through the sample space containing the liquid phase and the pulse frequency is sufficiently fast so that a given molecule of the chosen molecule will not pass in and out of the sample space within the pulse frequency.
G01N 21/3504 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing gases, e.g. multi-gas analysis
Absorption-biased NDIR gas sensors can be recalibrated by adjusting a calibration curve obtained from a gamma ratio ("G") that has been normalized by the gamma ratio when no sample gas is present in the sample chamber (*Go"), G being the ratio of a signal channel output ("Vs") of the NDIR gas sensor divided by a reference channel output ("VR") of the NDIR gas sensor. An AB NDIR gas sensor uses an identical spectral narrow band pass filter for wavelength selection for both a signal channel having a signal channel pathlength and a reference channel having a reference channel pathlength and an absorption bias is applied to the signal channel by making the signal channel path length longer than the reference channel pathlength. Recalibration can be achieved by adjusting Go based upon a reversed calibration curve algorithm that uses a concentration of sample gas determined by a master NDIR gas sensor.
An NDIR gas sensor is housed within a mechanical housing made up of a can and a header housing. The header housing body contains a tunnel waveguide sample chamber. The header housing also has a top surface with a pair of windows formed in it and a signal detector, a reference detector, an infrared source and a signal processor mounted to it. The can has inner reflective surfaces and the reference detector and the signal detector are affixed to the top surface so that the inner reflective surfaces of the can and the sample chamber aeate a signal channel path length detected by the signal detector that is greater than a reference channel path length detected by the reference detector and an absorption bias between the signal and reference outputs can be used to determine a gas concentration in the sample chamber.
An NDIR gas sensor and methodology use an absorption bias between signal and reference outputs to determine sample concentration of a gas being measured The absorption bias is created by using a signal channel in a sample chamber with a signal path length that is greater than a reference path length of a reference channel in the sample chamber while both the signal and reference detectors have an identical narrow band pass filter with the same Center Wavelength ("CWL"), Full Width Half Maximum (FWHM) and transmittance efficiency at the CWL Performance is improved when the reference detector and the signal detector share a common thermal platform that can also be shared by the sample chamber and the infrared source.
NDIR gas sensing methodology is advanced which renders the output of an NDIR gas sensor, when implemented with this new methodology, to remain stable or drift-free over time. Furthermore, the output of such a sensor will also be independent of the temperature of an environ wherein the sensor is in physical contact. This method utilizes the same narrow band-pass spectral filter for the detection of the gas of interest for both the signal and the reference channels. By so doing, the two channels always receive radiation of the same spectral content from the infrared source of the sensor convoluted with that from any external elements exposed to the sensor.
G01N 21/27 - ColourSpectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection
19.
HOLDER FOR A NASAL BREATHING AIR FILTRATION DEVICE OR DILATION DEVICE
A holder for a nasal air filtration device or dilation device. A holder for a nasal device may be a thin, generally "Z" or "S" shaped device that holds a nasal device in a substantially secure and stable position. Each of a nasal device's nasal bases can be placed or secured on a placement limb of the holder while a connecting member of the nasal device can be secured on the opposite side of the holder from where the nasal bases are positioned along a vertical portion of the holder relative to the placement limbs. There may be securing notches in the holder that help secure a nasal device at generally the point where the bases of the nasal device attach to the connecting member of the nasal device. The notches may allow a nasal device to be securely attached to the holder.
A nasal air filtration device includes a pair of either planar or concave-convex filters, a support structure incorporating a pair of generally annular bases or sleeves for supporting the filters, and a bridge that couples the bases or sleeves to maintain them in a desired spaced-apart relation and to determine a desired angular relationship. The support structure is insertable into the nasal cavities to position the filters within corresponding nasal cavities. Flexible rims maintain the support structure and the filters in spaced-apart relation to the surrounding nasal wall. The filters may be placed within the bases at an angle with respect to the walls of the bases. Also, the filtration device may be flesh tone in color, thereby blending with the skin tone of the user. In some embodiments, a post structure is supplied for supplying a scent or aroma to the wearer.
patents
