Abstract

22 assisted crystallization of a chemical species, in particular from a mixture comprising said chemical species, and a crystal obtained by said method. The chemical species is typically provided in a mother liquid, typically being a solution, and crystals are typically obtained directly thereof.

IPC Classes  ?

• C07C 51/43 - SeparationPurificationStabilisationUse of additives by change of the physical state, e.g. crystallisation
• C07C 63/26 - 1,4-Benzenedicarboxylic acid

Abstract

A method for processing natural or synthetic leather by using super-critical CO2. The leather can be dried leather, low grade leathers, thin leather, crust leathers, finished leathers, wet blue leathers, and tanned leather, as well as synthetic leather. In a second aspect the invention relates to leather obtained by said method, and in a third aspect to a stand-alone apparatus for performing said method.

IPC Classes  ?

• C14C 9/02 - Impregnating leather for preserving, waterproofing, making resistant to heat or similar purposes using fatty or oily materials, e.g. fat liquoring
• D06M 23/10 - Processes in which the treating agent is dissolved or dispersed in organic solventsProcesses for the recovery of organic solvents thereof
• D06P 3/32 - Leather
• D06P 1/94 - General processes of dyeing or printing textiles or general processes of dyeing leather, furs or solid macromolecular substances in any form, classified according to the dyes, pigments or auxiliary substances employed using dyes dissolved in solvents which are in the supercritical state

Abstract

The invention provides a method for extraction of at least one extract compound from a material, comprising: a. contacting carbon dioxide with the material to dissolve an amount of the at least one extract compound from the material into the carbon dioxide; b. contacting the carbon dioxide comprising the at least dissolved extract compound with a sorbent to sorb the at least one extract compound onto the sorbent and for regenerating the carbon dioxide; c. recirculating the regenerated carbon dioxide; and d. repeating said recirculating at a constant density of said carbon dioxide of between 100 and 1000 kg/m3, and repeating said recirculating for at least 10 cycles.

IPC Classes  ?

• B01D 11/02 - Solvent extraction of solids

Abstract

The invention provides a method for extraction of at least one extract compound from a material, comprising: • a. contacting carbon dioxide with the material to dissolve an amount of the at least one extract compound from the material into the carbon dioxide; • b. contacting the carbon dioxide comprising the at least dissolved extract compound with a sorbent to sorb the at least one extract compound onto the sorbent and for regenerating the carbon dioxide; • c. recirculating the regenerated carbon dioxide; and • d. repeating said recirculating at a constant density of said carbon dioxide of between 100 and 1000 kg/m 3, and repeating said recirculating for at least 10 cycles.

IPC Classes  ?

• B01D 11/02 - Solvent extraction of solids
• A23F 5/16 - Removing unwanted substances
• A23F 5/20 - Reducing or removing alkaloid contentPreparations produced therebyExtracts or infusions thereof
• A23G 1/00 - CocoaCocoa products, e.g. chocolateSubstitutes therefor
• A23L 11/30 - Removing undesirable substances, e.g. bitter substances
• A23L 27/10 - Natural spices, flavouring agents or condimentsExtracts thereof
• A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
• A61K 36/185 - Magnoliopsida (dicotyledons)
• B27K 7/00 - Chemical or physical treatment of cork
• C11B 9/02 - Recovery or refining of essential oils from raw materials

Abstract

The invention relates to the marking of textile products that have been dyed using a supercritical dyeing process. More particularly, the invention provides a process of marking a textile substrate with a tracer, said process comprising contacting the textile substrate with a supercritical or near-critical dyeing medium containing a dye and a tracer, said tracer being selected from a metal chelate and a chemiluminescent agent. The process of the present invention uses the supercritical or near-critical dyeing medium as a vehicle for depositing a tracer onto the textile substrate that is also dyed using this medium. The presence of the deposited tracer on the dyed textile can be detected using a simple and reliable authentication method. The invention also concerns a marked textile product obtained by the aforementioned process. Also provided are a dyeing composition that can be used in the aforementioned process as well as methods for authenticating textile products that have been marked using his process.

IPC Classes  ?

• D06P 1/00 - General processes of dyeing or printing textiles or general processes of dyeing leather, furs or solid macromolecular substances in any form, classified according to the dyes, pigments or auxiliary substances employed
• D06P 1/94 - General processes of dyeing or printing textiles or general processes of dyeing leather, furs or solid macromolecular substances in any form, classified according to the dyes, pigments or auxiliary substances employed using dyes dissolved in solvents which are in the supercritical state
• D06P 1/81 - General processes of dyeing or printing textiles or general processes of dyeing leather, furs or solid macromolecular substances in any form, classified according to the dyes, pigments or auxiliary substances employed using dyes dissolved in inorganic solvents
• B41M 3/14 - Security printing
• G01N 33/36 - Textiles
• B41M 3/00 - Printing processes to produce particular kinds of printed work, e.g. patterns
• D06H 1/00 - Marking textile materialsMarking in combination with metering or inspecting

Abstract

A method of preparing an edible oil composition, suitable for use in the preparation of a food product, comprises mixing from 1 % to 15 % by weight of fat particles with a liquid oil and storing the resulting composition for up to 10 weeks, wherein the mixing and storing conditions provide the composition in a form after storage that is pourable.

IPC Classes  ?

• A23D 9/00 - Other edible oils or fats, e.g. shortenings or cooking oils
• A23D 9/02 - Other edible oils or fats, e.g. shortenings or cooking oils characterised by the production or working-up
• A23D 9/05 - Forming free-flowing pieces

Abstract

Disclosed is a novel method of making a structuring agent for edible dispersions such as margarines or spreads. Fat, or another structuring component, is subjected to a process involving mixing it with liquefied gas or supercritical gas, and expanding the mixture through an orifice. In the invention, water is added to the mixture prior to expansion, so as to provide a spray liquid in the form of a fat and water emulsion.

IPC Classes  ?

• A23D 7/00 - Edible oil or fat compositions containing an aqueous phase, e.g. margarines
• A23D 9/05 - Forming free-flowing pieces
• C11B 15/00 - Solidifying fatty oils, fats, or waxes by physical processes

Abstract

The present invention relates to a method of preparing a pharmaceutical co-crystal composition, said method comprising the steps of: a. simultaneously contacting a supercritical or liquefied gas with solid particles of a pharmaceutically active component and with solid particles of a co-builder to form a co -crystallisation medium containing dissolved pharmaceutically active component and dissolved co-builder as well as solid particles of the pharmaceutically active component and solid particles of the co-builder; b. transforming the solid particles of the pharmaceutically active component and the solid particles of the co-builder into co-crystals of said pharmaceutically active component and said co-builder by keeping the supercritical or liquefied gas in a supercritical or liquid state until at least 80 wt.% of the pharmaceutically active component is incorporated in the crystal matrix of said co-crystals; and c. separating said co-crystals from the supercritical or liquefied gas wherein at least a fraction of the pharmaceutically active component and at least a fraction of the co-builder remain in an undissolved state during the co-crystallisation. The present method enables easy preparation of a pharmaceutical co-crystal composition containing virtually no solvent residue and can suitably be used to prepare co-crystals of highly labile pharmaceutically active components.

IPC Classes  ?

• A61K 9/14 - Particulate form, e.g. powders
• B01J 3/00 - Processes of utilising sub-atmospheric or super-atmospheric pressure to effect chemical or physical change of matterApparatus therefor
• B01D 9/00 - Crystallisation

Abstract

The invention relates to a method for desolventising a contaminated solid particulate composition containing: - at least 10 wt.% of a solid pharmaceutically active ingredient or of a solid intermediate product of the manufacture of a pharmaceutically active ingredient; - not more than 70 wt.% of contaminating solvent; and - optionally, up to 89 wt.% of inert carrier; said method comprising the steps of: a) contacting the contaminated solid particulate composition with a liquefied gas; b) allowing the contaminating solvent to become entrained in the liquefied gas; c) separating liquefied gas containing entrained contaminating solvent from the residual solid particulate composition; and d) removing liquefied gas from the residual solid particulate composition through evaporation; wherein all of the aforementioned steps are performed at a temperature below 100 ºC and below the critical temperature of the liquefied gas, and wherein steps a) to c) are performed at a pressure of at least 5 bar. Although the present method employs mild processing conditions, it enables essentially complete solvent removal.

IPC Classes  ?

• A61K 9/14 - Particulate form, e.g. powders
• A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
• A61K 38/00 - Medicinal preparations containing peptides
• A61K 47/30 - Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
• B01D 11/02 - Solvent extraction of solids
• B01J 8/00 - Chemical or physical processes in general, conducted in the presence of fluids and solid particlesApparatus for such processes

Abstract

The invention provides a photo bioreactor (1) comprising a vessel (10) containing an aqueous liquid comprising a photosynthetic culture and a light distributor (30). The light distributor has a surface (31) arranged to receive light (40) and a tapered surface (32) arranged to emit at least part of the received light. At least part of the tapered surface. (32) is submerged in the aqueous liquid comprising the photosynthetic culture. Light may be distributed efficiently in the aqueous liquid comprising the photosynthetic culture by relatively simple and cheap means. The reactor allows a high illuminated volume fraction.

IPC Classes  ?

• C12M 1/00 - Apparatus for enzymology or microbiology
• C12N 1/12 - Unicellular algaeCulture media therefor
• G02B 6/00 - Light guidesStructural details of arrangements comprising light guides and other optical elements, e.g. couplings

Abstract

A process for the preparation of encapsulates, employs: a pumpable emulsion having (i) a continuous phase containing a solvent and a matrix-forming solute dissolved in the solvent and (ii) a dispersed phase; an extractant including supercritical, subcritical or liquefied gas; the solvent being substantially more soluble in the extractant than the matrix-forming solute and the process including the successive steps of: a) combining the pumpable emulsion with the extractant under mixing conditions; b) allowing the formation of particulate encapsulates in which the dispersed phase is encased in a solid matrix of the matrix-forming solute; c) collecting the encapsulates and separating them from the extractant. The present processes is particularly suitable for producing particles containing active ingredients that are very sensitive, whose activity is adversely affected by exposure to oxygen, light, moisture, heat and/or friction.

IPC Classes  ?

• A61K 9/16 - AgglomeratesGranulatesMicrobeadlets
• A61K 9/66 - Sustained or differential release type containing emulsions, dispersions or solutions