Latilactobacillus sakeiLatilactobacillus sakei CNSC001WB strain deposited with accession number KCTC15217BP; and use thereof. The strain has an immunomodulatory function, i.e., an anti-inflammatory or immune function-enhancing effect, and thus can be used in a pharmaceutical composition, a food composition, a food additive composition, a health functional food composition, or an animal feed composition, for immunomodulation or anti-inflammation or immune function enhancement.
The present invention relates to a composition for hangover relief, comprising a noni fruit extract or a fraction thereof, and more specifically provides a noni fruit extract or a fraction thereof, which is prepared using a certain concentration of ethanol as an extraction solvent, to contain a large amount of polysaccharides having excellent hangover relieving functionality and an average molecular weight of 8 kDa to 10 kDa.
A61K 31/715 - Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkagesDerivatives thereof, e.g. ethers, esters
A61P 43/00 - Drugs for specific purposes, not provided for in groups
3.
Probiotic Lyophilizate Reactivation Composition for Improving Intestinal Survivability and Adhesion of Probiotics
Disclosed herein is a Zeta-bio composition for reactivating lyophilized probiotics by conferring a negative zeta-potential on the cell surface of the probiotics, the composition comprising as a reactivator at least one selected from the group consisting of L-lysine, L-ornithine, L-tyrosine, and L-histidine. The composition activates lyophilized probiotics by conferring a negative zeta-potential thereon, with the consequent improvement of intestinal survivability and adhesion in the lyophilized probiotics in addition to exhibiting a restorative effect from cell damage due to lyophilization.
The present invention relates to a composition for the prevention or treatment of respiratory diseases containing an Agastache rugosa and licorice extract as an active ingredient, and more specifically, the present invention relates to a composition for the prevention or treatment of respiratory diseases caused by fine dust containing an extract, in which Agastache rugosa and licorice are mixed at a weight ratio of 1:1 to 6:1, as an active ingredient.
The present invention relates to a composition for the prevention or treatment of respiratory diseases containing an Agastache rugosa and licorice extract as an active ingredient, and more specifically, the present invention relates to a composition for the prevention or treatment of respiratory diseases caused by fine dust containing an extract, in which Agastache rugosa and licorice are mixed at a weight ratio of 1:1 to 6:1, as an active ingredient.
The Agastache rugosa and licorice extract of the present invention has the efficacies of reducing cough through inhibition of TRPV1 activity, reducing lung inflammation through inhibition of CXCR1 and CXCR2 activities and GR-1+CD11b+ cell ratio reduction, and suppressing sputum production through inhibition of MUC5AC activity. In particular, since it is confirmed that the efficacy of the Agastache rugosa and licorice complex mixture is maximized at a specific mixing ratio, it can be widely utilized as a composition for the prevention or treatment of respiratory diseases caused by fine dust.
05 - Pharmaceutical, veterinary and sanitary products
29 - Meat, dairy products, prepared or preserved foods
30 - Basic staples, tea, coffee, baked goods and confectionery
32 - Beers; non-alcoholic beverages
Goods & Services
Plant extracts, other than essential oils, for pharmaceutical use; plant and herb extracts, other than essential oils, for medicinal purposes; nutraceuticals for use as a dietary supplement; nutraceutical preparations for therapeutic or medical purposes; plant extracts for pharmaceutical use mainly based on Annurca apple; plant extracts for medicinal purposes mainly based on Annurca apple; nutraceuticals for use as a dietary supplement mainly based on Annurca apple; nutraceutical preparations for medical purposes mainly based on Annurca apple Fruit, processed; dried fruits; pressed fruit paste; preserved, dried and cooked fruit and vegetables; fruit-based concentrate for cooking; fruit juices for cooking; food products made primarily from fruits, namely, fruit-based food snacks; Annurca apple, processed; food products made primarily from Annurca apple, namely, apple puree Fruit paste for flavoring of food; Fruit products made primarily from fruits, namely, fruit pies; food products made primarily from Annurca apple, namely, apple tarts Concentrated fruit juice; fruit drinks and juices; fruit-based beverages; fruit juice concentrates; non-alcoholic fruit juice beverages; concentrates for making fruit drinks; powders used in the preparation of fruit-based beverages; fruit syrups for beverages; concentrated fruit juice made primarily from Annurca apple; fruit drinks made primarily from Annurca apple; fruit juice made primarily from Annurca apple
Agastache rugosa and licorice complex mixture of the present invention has the synergy effects for the efficacies of reducing cough through inhibition of TRPV1 activity, reducing lung inflammation through inhibition of CXCR1 and CXCR2 activities and GR-1+CD11b+ cell ratio reduction, and suppressing sputum production through inhibition of MUC5AC activity and therefore it can be widely utilized as a composition for the prevention or treatment of respiratory diseases.
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
The present invention relates to a functional food composition for enhancing muscular function and exercise performance and a method for preparing same. According to the present invention, provided is a composition which enables increased generation of factors associated with myogenesis and energy metabolism and thus enhances exercise performance and muscular function. More particularly, mitochondria and muscle cell synthesis is increased and muscular atrophy is inhibited, and thus muscle exercise effects can be increased and fatigue is reduced. The composition can be applied as a health function composition to various fields such as foods.
A composition for strengthening a skin barrier or moisturizing skin is provided. The composition includes tilianin. The composition may be a food, a health functional food composition, a quasi-drug composition and/or a composition for external use on the skin. The composition increases the contents of moisture and hyaluronic acid in the skin and exhibits an upregulating effect on HAS. A method for strengthening a skin barrier or enhancing skin moisture using tilianin, and provides a use of tilianin in the preparation of food or medicine for strengthening a skin barrier or enhancing skin moisture are also provided.
The present invention relates to a composition capable of inhibiting, preventing, and ameliorating skin aging caused by light due to the inclusion of an Agastache rugosa extract and collagen peptide as active ingredients. The present invention can minimize irritation to the skin due to the inclusion of a material extracted from a natural product.
COMPOSITION COMPRISING AGASTACHE RUGOSA EXTRACT, AND USE THEREOF FOR IMPROVING MUSCULAR FUNCTION OR PREVENTING, RELIEVING, OR TREATING MUSCULAR DISEASES
Agastache rugosaAgastache rugosaAgastache rugosa extract, and provides a use of an Agastache rugosa extract when preparing a food or a medicine for improving muscular function or preventing, relieving, or treating muscular diseases.
The present invention relates to a composition comprising a euscaphic acid, and the use thereof for relieving fatigue and, more specifically, to a food composition, a health functional food composition, and/or a pharmaceutical composition for relieving fatigue by means of euscaphic acid which exhibits a physical fatigue-relieving effect through anti-inflammatory and antioxidant activities. Further, the present invention provides a fatigue relieving method using a euscaphic acid, and the use of a euscaphic acid when preparing a food product or a drug for relieving fatigue.
The present invention relates to a composition containing euscaphic acid and use thereof for improving muscular function or enhancing exercise performance and, more specifically, to a food composition, a health functional food composition and/or a pharmaceutical composition for improving muscular function or enhancing exercise performance by using euscaphic acid, which improves muscular function and exhibits an excellent effect of enhancing exercise performance by controlling various factors involved in muscle damage, muscle fatigue, and/or endurance. Furthermore, the present invention provides a method for improving muscular function or enhancing exercise performance by using euscaphic acid and provides use of euscaphic acid in the manufacture of a food or medicine for improving muscular function or enhancing exercise performance.
The present invention relates to a composition for enhancing immunity or a composition for preventing or ameliorating neurodegenerative diseases, both of which contain, as an active ingredient, a mixture extract of goji berries, mulberries and jujubes or an extract mixture thereof.
One aspect of the present disclosure relates to a Zeta-bio composition for reactivating freeze-dried probiotics and imparting negatively charged zeta potential to the surfaces of the probiotic cells, the composition comprising, as a reactivator, at least one selected from the group consisting of L-lysine, L-ornithine, L-tyrosine and L-histidine. In the present disclosure, freeze-dried probiotics are activated so that negatively charged zeta potential is exhibited and the effects of improving intestinal viability and adhesion to intestines of the freeze-dried probiotics and causing the recovery of cell damage caused by freeze-drying are exhibited.
The present invention relates to a composition for hangover relief, comprising a noni fruit extract or a fraction thereof and, more specifically, provides a noni fruit extract or a fraction thereof, which is prepared using a certain concentration of ethanol as an extraction solvent, to contain a large amount of polysaccharides having excellent hangover relieving functionality and an average molecular weight of 8-10 kDa.
A23L 5/20 - Removal of unwanted matter, e.g. deodorisation or detoxification
16.
Method for preparing iridoid-rich noni fruit extract or fraction thereof, method for preparing immune-enhancing active material-rich noni fruit extract or fraction thereof and use of noni fruit extract or fraction thereof
The present invention relates to a method of preparing a noni fruit extract containing a high iridoid content or a fraction thereof, a method of preparing a noni fruit extract containing a high content of an immune-enhancing active substance or a fraction thereof, and a use of a noni fruit extract or a fraction thereof, and more specifically, the present invention provides a method of preparing a noni fruit extract containing a high iridoid content or a fraction thereof, including preparing a noni fruit extract by using ethanol in a specific concentration range as an extraction solvent, a method of preparing a noni fruit extract containing a high content of an immune-enhancing active substance or a fraction thereof, a pharmaceutical composition for enhancing immunity including the extract or a fraction thereof, a health functional food composition including the same constitution, a method of enhancing immunity using the extract or a fraction thereof, and a use of the extract or a fraction thereof in preparation of medicine for preventing or treating a disease associated with immune enhancement or reduced immunity.
A61K 31/7048 - Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin
17.
COMPOSITION, CONTAINING AGASTACHE RUGOSA AND LICORICE EXTRACT AS ACTIVE INGREDIENT, FOR PREVENTING OR TREATING RESPIRATORY DISEASES CAUSED BY FINE DUST
The present invention relates to a composition for preventing or treating respiratory diseases, the composition containing an Agastache rugosa and licorice extract as an active ingredient, and more particularly, to a composition which is for preventing or treating respiratory diseases caused by fine dust, and contains, as an active ingredient, an extract in which agastache rugosa and licorice are mixed in a weight ratio of 1:1 to 6:1. The Agastache rugosa and licorice extract according to the present invention has the effects of: reducing coughing through the inhibition of TRPV1 activity; reducing lung inflammation through the inhibition of CXCR1 and CXCR2 activity and the reduction of GR-1+CD11b+ cell ratio; and inhibiting phlegm production through the inhibition of MUC5AC activity. In particular, it was observed that the efficacy of a complex mixture of Agastache rugosa and licorice is maximized at a specific mixing ratio. Thus, the present invention can be effectively used as a composition for preventing or treating respiratory diseases caused by fine dust.
A61P 11/00 - Drugs for disorders of the respiratory system
A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
18.
METHOD FOR PREPARING IRIDOID-RICH NONI FRUIT EXTRACT OR FRACTION THEREOF, METHOD FOR PREPARING IMMUNE-ENHANCING ACTIVE MATERIAL-RICH NONI FRUIT EXTRACT OR FRACTION THEREOF AND USE OF NONI FRUIT EXTRACT OR FRACTION THEREOF
The present invention relates to a method for preparing an iridoid-rich noni fruit extract or a fraction thereof, a method for preparing an immune-enhancing active material-rich noni fruit extract or a fraction thereof and the use of a noni fruit extract or a fraction thereof and, more specifically, to a method for preparing an iridoid-rich noni fruit extract or a fraction thereof, a method for preparing an immune-enhancing active material-rich noni fruit extract or a fraction thereof, an immune-enhancing pharmaceutical composition comprising the extract or the fraction thereof, a functional health food composition comprising the same constituents, an immune-enhancing method using the extract or the fraction thereof, and the use of the extract or the fraction thereof when preparing a drug for preventing or treating diseases associated with immune enhancement or immune deterioration, the method comprising a step of preparing a noni fruit extract by means of a particular concentration range of ethanol as an extraction solvent.
The present invention relates to a skin whitening composition and a manufacturing method therefor, and can improve whitening effects while minimizing chemical additives that may irritate the skin. Furthermore, the present invention can effectively prevent and relieve skin blackening by inhibiting the materials involved in melanin formation and melanin synthesis, and thus can be helpfully applied without cytotoxicity to various products.
The present invention relates to a detoxification composition and a producing method thereof, in which waste products or oxygen free radicals generated by metabolic processes or multiple byproducts resulting from stress, etc., exotoxins caused by the invasion of bacteria, endotoxins, and heavy metals and oxygen free radicals caused by toxic substances, etc., in plants or animals can be removed or released from the body.
A61Q 17/00 - Barrier preparationsPreparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
21.
Composition for improvement of muscle function containing 3,5-dicaffeoylquinic acid or chrysanthemum extract
Industry-Academic Cooperation Foundation, Yonsei University (Republic of Korea)
Cosmax NBT, Inc. (Republic of Korea)
Cosmax NS, Inc. (Republic of Korea)
Inventor
Hwang, Jae Kwan
Yun, Jun Gon
Kim, Mi Bo
Kim, Chang Hee
Lee, Joon Hyung
Kwon, Do Wan
Choi, Su Young
Kim, Jin Hak
Jang, Ji Hwan
Geum, Jeong Ho
Kweon, Min Son
Abstract
The present invention relates to a composition for preventing or treating a muscle disorder, which includes a chrysanthemum extract or 3,5-dicaffeoylquinic acid as an active ingredient, and specifically, it may be used to reduce mRNA expression of atrogin-1 and MuRF1, which are main biomarkers involved in muscle protein degradation and increase mRNA expression of the mTOR protein, which is a main biomarker involved in muscle protein formation, and myogenin and MyoD, which are biomarkers related to muscle differentiation, thereby reducing muscle loss, and thus the chrysanthemum extract or 3,5-dicaffeoylquinic acid can be used in prevention and treatment of a muscle disorder, or improvement in muscle function. In addition, the chrysanthemum extract or 3,5-dicaffeoylquinic acid increases the activity of SIRT1 and PGC-1α, which are the main biomarkers involved in exercise performance, thereby excellently enhancing exercise performance. In addition, the present invention is a natural substance and may be safely used without a side effect, and therefore may be used as a medication, food or a cosmetic.
The present invention relates to a method of preparing a lyophilizate of a Taheebo alcohol extract, including: (a) extracting Taheebo with an alcohol and concentrating an extract; and (b) lyophilizing the alcohol-extracted and concentrated Taheebo, and a composition for the treatment, prevention or amelioration of an inflammatory disease including a lyophilizate of a Taheebo alcohol extract prepared therefrom.
A61K 9/00 - Medicinal preparations characterised by special physical form
A61Q 17/00 - Barrier preparationsPreparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
