45 - Legal and security services; personal services for individuals.
Goods & Services
(1) Indexing information related to sexual minority rights, legal rights and human rights for data reporting purposes; monitoring sexual minority rights, legal rights and human rights for data reporting purposes.
(2) Providing information in the form of an index relating to sexual minority rights, legal rights and human rights.
45 - Legal and security services; personal services for individuals.
Goods & Services
Providing an index in relation to sexual minority legal and human rights. Providing information in relation to sexual minority legal and human rights; monitoring sexual minority legal and human rights for data reporting purposes.
45 - Legal and security services; personal services for individuals.
Goods & Services
Providing an index in relation to sexual minority legal and human rights; monitoring sexual minority legal and human rights for data reporting purposes Providing information in relation to sexual minority legal and human rights
45 - Legal and security services; personal services for individuals.
Goods & Services
Providing an index in relation to sexual minority legal and human rights; Monitoring sexual minority legal and human rights for data reporting purposes Providing information in relation to sexual minority legal and human rights
7.
Site specifically incorporated initiator for growth of polymers from proteins
The present invention is directed towards a protein-polymer composition having a protein with a site-specifically incorporated unnatural amino acid initiator and a covalently attached polymer.
A61K 47/48 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
C08F 220/26 - Esters containing oxygen in addition to the carboxy oxygen
C07C 69/00 - Esters of carboxylic acidsEsters of carbonic or haloformic acids
C12N 9/96 - Stabilising an enzyme by forming an adduct or a compositionForming enzyme conjugates
8.
Portable copystand for enhancing ink/parchment contrast
A portable copystand is disclosed having a foldable base. A first adjustable arm and a second adjustable arm are provided. The portable copystand also has an ultraviolet light source and a visible spectrum light source.
This invention relates to a process for the phase-controlled synthesis of ternary and quaternary mixed-metal sulfide nanoparticles by reacting soft metal ions with hard metal ions in a high-boiling organic solvent in the presence of a complexing and activating ligands to control the reactivity of the metal ions. Ternary and quaternary mixed metal sulfides nanoparticles of copper, sulfur, and iron, aluminum, tin, and silicon are preferred. This invention also relates to the phase controlled preparation of polymorphs of bornite nanoparticles and the phase controlled preparation of stabilized α- and γ-chalconite nanoparticles.
H01B 1/10 - Conductors or conductive bodies characterised by the conductive materialsSelection of materials as conductors mainly consisting of other non-metallic substances sulfides
10.
GENETICALLY ENCODED INITIATOR FOR POLYMER GROWTH FROM PROTEINS
This invention pertains to methods for producing homogeneous recombinant proteins that contain polymer initiators at defined sites. The unnatural amino acid, 4-(2'-bromoisobutyramido)phenylalanine of formula 1, was designed and synthesized as a molecule comprising a functional group further comprising an initiator for an atom-transfer radical polymerization (ATRP") that additionally would provide a stable linkage between the protein and growing polymer. We evolved a Methanococcus jannaschii (Mj) tyrosyl-tRNA synthetase/tRNAcuA pair to genetically encode this unnatural amino acid in response to an amber codon. To demonstrate the utility of this functional amino acid, we produced Green Fluorescent Protein with the unnatural amino acid initiator of formula 1 site- specifically incorporated on its surface (GFP-1). Purified GFP-1 was then used as an initiator under standard ATRP conditions with oligo(ethylene oxide) mononiethyl ether methacrylate, efficiently producing a polymer-GFP bioconjugate wherein the polymer is connected at a specifically selected site on GFP.
19F-labelled amino acids, into proteins or peptides. Such amino acids may be used as an NMR probe for characterizing protein structure, dynamics, and reactivity or for radionuclide imaging (e.g., PET). Fluorinated amino acids may also be used to stabilize proteins or peptides.
This invention relates, in part, to newly identified polynucleotides, polypeptides, variants and derivatives thereof; processes for making the polynucleotides and the polypeptides, and their variants and derivatives; and uses of the polynucleotides, polypeptides, variants and derivatives. The invention also relates to compositions of orthogonal aminoacyl-tRNA synthetases, and pairs of orthogonal aminoacyl-tRNA synthetases, and orthogonal tRNAs that incorporate fluorinated amino acids into proteins in response to selector codons. The present invention also includes translation biochemistry methods for site-specific incorporation of fluorinated amino acids, for example, 18F- or 19F-labelled amino acids, into proteins or peptides. Such amino acids may be used as an NMR probe for characterizing protein structure, dynamics, and reactivity or for radionuclide imaging (e.g., PET). Fluorinated amino acids may also be used to stabilize proteins or peptides.
41 - Education, entertainment, sporting and cultural services
Goods & Services
Clothing, namely shirts, pants, vests, sweatshirts, sweaters, and jackets Educational services, namely providing courses of instruction at the college level