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Found results for
 patents
1.
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METHOD FOR INCREASING HALF-LIFE OF BOTULINUM TOXIN TYPE A LIGHT CHAIN PROTEIN
| Application Number |
19022740 |
| Status |
Pending |
| Filing Date |
2025-01-15 |
| First Publication Date |
2025-07-17 |
| Owner |
UBIPROTEIN. CORP (Republic of Korea)
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| Inventor |
- Kim, Myung-Sun
- Lim, Hye-Young
- Oh, Su-Kyung
- Lee, Jae-Woo
- Bae, Sung-Ryul
- Choi, Seung-In
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Abstract
The present invention relates to: a method for increasing the half-life of a botulinum toxin type A light chain (AUT-BT-LC) protein, the method comprising substituting one or more lysine residues present in the amino acid sequence of the botulinum toxin type A light chain (BT-LC) protein; or a botulinum toxin type A light chain (AUT-BT-LC) protein having an increased half-life. The protein having an increased half-life according to the present invention may be used in a cosmetic composition and a pharmaceutical composition.
IPC Classes ?
- C07K 14/33 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Clostridium (G)
- A61K 39/00 - Medicinal preparations containing antigens or antibodies
- C12N 15/70 - Vectors or expression systems specially adapted for E. coli
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2.
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DUAL-FUNCTIONAL COSMETIC COMPOSITION AND PREPARING METHOD THEREOF
| Application Number |
18424838 |
| Status |
Pending |
| Filing Date |
2024-01-28 |
| First Publication Date |
2024-05-16 |
| Owner |
UBIPROTEIN CORP (Republic of Korea)
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| Inventor |
- Kim, Myung-Sun
- Oh, Su Kyung
- Kim, Kyunggon
- Baek, Kwang-Hyun
- Bae, Sung-Ryul
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Abstract
The present invention relates to a method for extending a half-life of a protein, comprising substituting one lysine residue in each of the amino acid sequences in two proteins, or to a protein having an extended half-life. The protein in which lysine residues have been substituted according to the present invention remains in the body for an extended period of time, and exhibits excellent treatment results. In addition, two proteins can be produced and provided in a single production process.
IPC Classes ?
- A61K 8/64 - ProteinsPeptidesDerivatives or degradation products thereof
- A61Q 19/00 - Preparations for care of the skin
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3.
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METHOD FOR INCREASING HALF-LIFE OF BOTULINUM TOXIN TYPE A LIGHT CHAIN PROTEIN
| Application Number |
KR2023010454 |
| Publication Number |
2024/019553 |
| Status |
In Force |
| Filing Date |
2023-07-19 |
| Publication Date |
2024-01-25 |
| Owner |
UBIPROTEIN. CORP (Republic of Korea)
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| Inventor |
- Kim, Myung-Sun
- Lim, Hye-Young
- Oh, Su-Kyung
- Lee, Jae-Woo
- Bae, Sung-Ryul
- Choi, Seung-In
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Abstract
The present invention relates to: a method for increasing the half-life of a botulinum toxin type A light chain (AUT-BT-LC) protein, the method comprising substituting one or more lysine residues present in the amino acid sequence of the botulinum toxin type A light chain (BT-LC) protein; or a botulinum toxin type A light chain (AUT-BT-LC) protein having an increased half-life. The protein having an increased half-life according to the present invention may be used in a cosmetic composition and a pharmaceutical composition.
IPC Classes ?
- C12N 9/52 - Proteinases derived from bacteria
- C07K 14/33 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Clostridium (G)
- A61K 8/66 - Enzymes
- A61K 38/48 - Hydrolases (3) acting on peptide bonds (3.4)
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4.
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METHOD FOR EXTENDING HALF-LIFE OF A PROTEIN
| Application Number |
17990460 |
| Status |
Pending |
| Filing Date |
2022-11-18 |
| First Publication Date |
2023-10-19 |
| Owner |
UBIPROTEIN, CORP. (Republic of Korea)
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| Inventor |
- Kim, Kyunggon
- Baek, Kwang-Hyun
- Bae, Sung-Ryul
- Kim, Myung-Sun
- Kim, Hyeonmi
- Yoo, Yeeun
- Li, Lan
- Park, Jung-Hyun
- Kim, Jin-Ok
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Abstract
The present invention relates to a method for prolonging half-life of a protein or a (poly)peptide by replacing one or more amino acid residues of the protein. Further, the present invention is about the protein having a prolonged half-life prepared by the method above.
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5.
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METHOD FOR EXTENDING HALF-LIFE OF A PROTEIN
| Application Number |
17990438 |
| Status |
Pending |
| Filing Date |
2022-11-18 |
| First Publication Date |
2023-08-10 |
| Owner |
UBIPROTEIN, CORP. (Republic of Korea)
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| Inventor |
- Kim, Kyunggon
- Baek, Kwang-Hyun
- Bae, Sung-Ryul
- Kim, Myung-Sun
- Kim, Hyeonmi
- Yoo, Yeeun
- Li, Lan
- Park, Jung-Hyun
- Kim, Jin-Ok
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Abstract
The present invention relates to a method for prolonging half-life of a protein or a (poly)peptide by replacing one or more amino acid residues of the protein. Further, the present invention is about the protein having a prolonged half-life prepared by the method above.
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6.
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METHOD FOR EXTENDING HALF-LIFE OF A PROTEIN
| Application Number |
17990478 |
| Status |
Pending |
| Filing Date |
2022-11-18 |
| First Publication Date |
2023-08-03 |
| Owner |
UBIPROTEIN, CORP. (Republic of Korea)
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| Inventor |
- Kim, Kyunggon
- Baek, Kwang-Hyun
- Bae, Sung-Ryul
- Kim, Myung-Sun
- Kim, Hyeonmi
- Yoo, Yeeun
- Li, Lan
- Park, Jung-Hyun
- Kim, Jin-Ok
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Abstract
The present invention relates to a method for prolonging half-life of a protein or a (poly)peptide by replacing one or more amino acid residues of the protein. Further, the present invention is about the protein having a prolonged half-life prepared by the method above.
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7.
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METHOD FOR EXTENDING HALF-LIFE OF A PROTEIN
| Application Number |
17990492 |
| Status |
Pending |
| Filing Date |
2022-11-18 |
| First Publication Date |
2023-08-03 |
| Owner |
UBIPROTEIN, CORP. (Republic of Korea)
|
| Inventor |
- Kim, Kyunggon
- Baek, Kwang-Hyun
- Bae, Sung-Ryul
- Kim, Myung-Sun
- Kim, Hyeonmi
- Yoo, Yeeun
- Li, Lan
- Park, Jung-Hyun
- Kim, Jin-Ok
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Abstract
The present invention relates to a method for prolonging half-life of a protein or a (poly)peptide by replacing one or more amino acid residues of the protein. Further, the present invention is about the protein having a prolonged half-life prepared by the method above.
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8.
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METHOD FOR EXTENDING HALF-LIFE OF A PROTEIN
| Application Number |
17990497 |
| Status |
Pending |
| Filing Date |
2022-11-18 |
| First Publication Date |
2023-08-03 |
| Owner |
UBIPROTEIN, CORP. (Republic of Korea)
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| Inventor |
- Kim, Kyunggon
- Baek, Kwang-Hyun
- Bae, Sung-Ryul
- Kim, Myung-Sun
- Kim, Hyeonmi
- Yoo, Yeeun
- Li, Lan
- Park, Jung-Hyun
- Kim, Jin-Ok
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Abstract
The present invention relates to a method for prolonging half-life of a protein or a (poly)peptide by replacing one or more amino acid residues of the protein. Further, the present invention is about the protein having a prolonged half-life prepared by the method above.
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9.
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METHOD FOR EXTENDING HALF-LIFE OF A PROTEIN
| Application Number |
17990507 |
| Status |
Pending |
| Filing Date |
2022-11-18 |
| First Publication Date |
2023-08-03 |
| Owner |
UBIPROTEIN, CORP. (Republic of Korea)
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| Inventor |
- Kim, Kyunggon
- Baek, Kwang-Hyun
- Bae, Sung-Ryul
- Kim, Myung-Sun
- Kim, Hyeonmi
- Yoo, Yeeun
- Li, Lan
- Park, Jung-Hyun
- Kim, Jin-Ok
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Abstract
The present invention relates to a method for prolonging half-life of a protein or a (poly)peptide by replacing one or more amino acid residues of the protein. Further, the present invention is about the protein having a prolonged half-life prepared by the method above.
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10.
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METHOD FOR EXTENDING HALF-LIFE OF A PROTEIN
| Application Number |
17990515 |
| Status |
Pending |
| Filing Date |
2022-11-18 |
| First Publication Date |
2023-08-03 |
| Owner |
UBIPROTEIN, CORP. (Republic of Korea)
|
| Inventor |
- Kim, Kyunggon
- Baek, Kwang-Hyun
- Bae, Sung-Ryul
- Kim, Myung-Sun
- Kim, Hyeonmi
- Yoo, Yeeun
- Li, Lan
- Park, Jung-Hyun
- Kim, Jin-Ok
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Abstract
The present invention relates to a method for prolonging half-life of a protein or a (poly)peptide by replacing one or more amino acid residues of the protein. Further, the present invention is about the protein having a prolonged half-life prepared by the method above.
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11.
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DUAL FUNCTIONAL COSMETIC COMPOSITIONS AND PREPARATION METHOD THEREFOR
| Application Number |
KR2022011256 |
| Publication Number |
2023/008974 |
| Status |
In Force |
| Filing Date |
2022-07-29 |
| Publication Date |
2023-02-02 |
| Owner |
UBIPROTEIN CORP (Republic of Korea)
|
| Inventor |
- Kim, Myung-Sun
- Oh, Su Kyung
- Kim, Kyunggon
- Baek, Kwang-Hyun
- Bae, Sung-Ryul
|
Abstract
The present invention relates to a method for extending a half-life of a protein, the method comprising substituting one lysine residue in each of the amino acid sequences in two proteins, or to a protein having an extended half-life. The protein in which lysine residues have been substituted according to the present invention persists in the body for an extended period of time, and exhibits excellent treatment results. In addition, two kinds of proteins can be produced and provided in a single production process.
IPC Classes ?
- C07K 14/50 - Fibroblast growth factor [FGF]
- C07K 14/485 - Epidermal growth factor [EGF], i.e. urogastrone
- A61K 8/64 - ProteinsPeptidesDerivatives or degradation products thereof
- A61Q 19/00 - Preparations for care of the skin
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12.
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A METHOD FOR EXTENDING HALF-LIFE OF A PROTEIN
| Application Number |
KR2016012334 |
| Publication Number |
2017/086627 |
| Status |
In Force |
| Filing Date |
2016-10-30 |
| Publication Date |
2017-05-26 |
| Owner |
UBIPROTEIN, CORP. (Republic of Korea)
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| Inventor |
- Kim, Kyunggon
- Baek, Kwang-Hyun
- Bae, Sung-Ryul
- Kim, Myung-Sun
- Kim, Hyeonmi
- Yoo, Yeeun
- Li, Lan
- Park, Jung-Hyun
- Kim, Jin-Ok
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Abstract
The present invention relates to a method for prolonging half-life of a protein or a (poly)peptide by replacing one or more amino acid residues of the protein. Further, the present invention is about the protein having a prolonged half-life prepared by the method above.
IPC Classes ?
- C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
- C07K 14/505 - Erythropoietin [EPO]
- C07K 14/535 - Granulocyte CSFGranulocyte-macrophage CSF
- C07K 14/61 - Growth hormone [GH], i.e. somatotropin
- C07K 14/62 - Insulins
- C07K 14/56 - IFN-alpha
- A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
- A61K 38/18 - Growth factorsGrowth regulators
- A61K 38/19 - CytokinesLymphokinesInterferons
- A61K 38/22 - Hormones
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