The present disclosure relates to Andes virus (ANDV) variants comprising one or more attenuating amino acid modifications, pharmaceutical compositions and vaccines comprising Andes virus variants, and methods of treating diseases and conditions via administration of Andes virus variants.
The disclosure relates to an adaptor comprising a body configured to be at least partially inserted into an open end of a bottle while forming a seal with an inner peripheral surface of the open end of the bottle, systems for use in delivering a liquid for treatment of an individual comprising the adaptor, and methods for irrigation of an eye using the adaptor.
3.
Wearable modular extracorporeal life support device for mobile treatment of single and multiorgan failure
In one exemplary embodiment, a wearable extracorporeal life support device includes a catheter fluidly connected to a pump and first and second modular extracorporeal life support components. The device may also be configured to be attached to a garment. The pump and the first and second modular extracorporeal life support components may be fluidly connected in series. The pump and the first and second modular extracorporeal life support components may also be fluidly connected in parallel. The first modular extracorporeal life support component may be a lung membrane and the second modular extracorporeal life support component may be a dialysis membrane.
A61M 60/00 - Blood pumpsDevices for mechanical circulatory actuationBalloon pumps for circulatory assistance
A61M 60/113 - Extracorporeal pumps, i.e. the blood being pumped outside the patient’s body incorporated within extracorporeal blood circuits or systems in other functional devices, e.g. dialysers or heart-lung machines
A61M 60/216 - Non-positive displacement blood pumps including a rotating member acting on the blood, e.g. impeller
FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH (USA)
U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND (USA)
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (USA)
NEW YORK UNIVERSITY (USA)
MCLEAN HOSPITAL CORPORATION (USA)
GENEVA FOUNDATION (USA)
Inventor
Dean, Kelsey R.
Doyle Iii, Francis J.
Mellon, Synthia H.
Wolkowitz, Owen M.
Lee, Inyoul
Hood, Leroy
Yang, Ruoting
Hammamieh, Rasha
Jett, Marti
Yehuda, Rachel
Marmar, Charles R.
Ressler, Kerry J.
Gautam, Aarti
Flory, Janine
Wang, Kai
Abstract
The invention described is directed to a method to treat PTSD in a subject which method includes identifying the subject as suffering from PTSD or likely to suffer from PTSD by virtue of assessing one or more of the markers set forth herein, and treating the subject thus identified.
G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
G16B 40/00 - ICT specially adapted for biostatisticsICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
A61P 25/00 - Drugs for disorders of the nervous system
In one exemplary embodiment, a wearable extracorporeal life support device includes a catheter fluidly connected to a pump and first and second modular extracorporeal life support components. The device may also be configured to be attached to a garment. The pump and the first and second modular extracorporeal life support components may be fluidly connected in series. The pump and the first and second modular extracorporeal life support components may also be fluidly connected in parallel. The first modular extracorporeal life support component may be a lung membrane and the second modular extracorporeal life support component may be a dialysis membrane.
A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
A61M 1/16 - Dialysis systemsArtificial kidneysBlood oxygenators with membranes
A61M 1/34 - Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration, diafiltration
A61M 60/113 - Extracorporeal pumps, i.e. the blood being pumped outside the patient’s body incorporated within extracorporeal blood circuits or systems in other functional devices, e.g. dialysers or heart-lung machines
A61M 60/31 - Medical purposes thereof other than the enhancement of the cardiac output for enhancement of in vivo organ perfusion, e.g. retroperfusion
A61M 60/37 - Haemodialysis, haemofiltration or diafiltration
In one exemplary embodiment, a wearable extracorporeal life support device includes a catheter fluidly connected to a pump and first and second modular extracorporeal life support components. The device may also be configured to be attached to a garment. The pump and the first and second modular extracorporeal life support components may be fluidly connected in series. The pump and the first and second modular extracorporeal life support components may also be fluidly connected in parallel. The first modular extracorporeal life support component may be a lung membrane and the second modular extracorporeal life support component may be a dialysis membrane.
patents
