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Found results for
 patents
1.
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Immunoassay for free vitamin D
| Application Number |
17150850 |
| Grant Number |
11927595 |
| Status |
In Force |
| Filing Date |
2021-01-15 |
| First Publication Date |
2021-05-06 |
| Grant Date |
2024-03-12 |
| Owner |
FUTURE DIAGNOSTICS B.V. (Netherlands)
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| Inventor |
- Martens, Michaël Franciscus Wilhelmus Cornelis
- Parsons, George Henry
- Rosmalen, Franciscus Maria Anna
- Swinkels, Leon Maria Jacobus Wilhelmus
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Abstract
2. The invention thus employs a binding protein to absorb the free 25(OH) vitamin D. Thereafter the binding protein comprising the 25-OH vitamin D is subjected to a competitive binding assay with a labeled vitamin D compound, preferably radiolabeled, fluorescent labeled, luminescent labeled, biotin labeled, gold labeled or enzyme labeled. Alternatively the immunocaptured 25-OH vitamin D can be quantitated by mass spectrometry.
IPC Classes ?
- G01N 33/82 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving vitamins
- G01N 1/28 - Preparing specimens for investigation
- G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor
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2.
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Immunoassay for free vitamin D
| Application Number |
15862318 |
| Grant Number |
10935557 |
| Status |
In Force |
| Filing Date |
2018-01-04 |
| First Publication Date |
2018-07-12 |
| Grant Date |
2021-03-02 |
| Owner |
FUTURE DIAGNOSTICS B.V. (Netherlands)
|
| Inventor |
- Martens, Michaël Franciscus Wilhelmus Cornelis
- Parsons, George Henry
- Rosmalen, Franciscus Maria Anna
- Swinkels, Leon Maria Jacobus Wilhelmus
|
Abstract
Disclosed is the invention to conduct immuno-adsorption of free 25(OH) vitamin D from blood or blood components, notably serum or plasma, after which the absorbed material is measured. A fluoro-alkyl surfactant is used to enhance the solubility of Vitamin D and allow the measurement of free Vitamin D. The invention thus employs a binding protein to absorb the free 25(OH) vitamin D. Thereafter the binding protein comprising the 25-OH vitamin D is subjected to a competitive binding assay with a labeled vitamin D compound, preferably radiolabeled, fluorescent labeled, luminescent labeled, biotin labeled, gold labeled or enzyme labeled. Alternatively the immunocaptured 25-OH vitamin D can be quantitated by mass spectrometry.
IPC Classes ?
- G01N 33/82 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving vitamins
- G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor
- G01N 1/28 - Preparing specimens for investigation
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3.
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Release reagent for vitamin D
| Application Number |
13993285 |
| Grant Number |
10422805 |
| Status |
In Force |
| Filing Date |
2011-12-27 |
| First Publication Date |
2014-05-29 |
| Grant Date |
2019-09-24 |
| Owner |
FUTURE DIAGNOSTICS B.V. (Netherlands)
|
| Inventor |
- Swinkels, Leon Maria Jacobus Wilhelmus
- Maas, Antonius Franciscus
- Martens, Michael Franciscus Wilhelmus Cornelis
|
Abstract
Disclosed is an invention in the field of conducting an immunoassay of 25(OH) vitamin D in blood or blood components, notably serum or plasma. The invention employs a perfluoro alkyl acid, or a salt thereof, to release 25(OH) vitamin D from vitamin D binding protein. Thereafter the binding protein comprising the 25-OH vitamin D is subjected to a competitive binding assay with a labeled vitamin D compound.
IPC Classes ?
- G01N 33/82 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving vitamins
|
4.
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Immunoassay for free vitamin D
| Application Number |
13638613 |
| Grant Number |
09897615 |
| Status |
In Force |
| Filing Date |
2011-04-01 |
| First Publication Date |
2013-06-06 |
| Grant Date |
2018-02-20 |
| Owner |
Future Diagnostics, B.V. (Netherlands)
|
| Inventor |
- Martens, Michaël Franciscus Wilhelmus Cornelis
- Parsons, George Henry
- Rosmalen, Franciscus Maria Anna
- Swinkels, Leon Maria Jacobus Wilhelmus
|
Abstract
Disclosed is the invention to conduct immuno-adsorption of free 25(OH) vitamin D from blood or blood components, notably serum or plasma, after which the absorbed material is measured. A fluoro-alkyl surfactant is used to enhance the solubility of Vitamin D and allow the measurement of free Vitamin D. The invention thus employs a binding protein to absorb the free 25(OH) vitamin D. Thereafter the binding protein comprising the 25-OH vitamin D is subjected to a competitive binding assay with a labeled vitamin D compound, preferably radiolabeled, fluorescent labeled, luminescent labeled, biotin labeled, gold labeled or enzyme labeled. Alternatively the immunocaptured 25-OH vitamin D can be quantitated by mass spectrometry.
IPC Classes ?
- G01N 33/82 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving vitamins
|
5.
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RELEASE REAGENT FOR VITAMIN D
| Document Number |
02821415 |
| Status |
In Force |
| Filing Date |
2011-12-27 |
| Open to Public Date |
2012-07-05 |
| Grant Date |
2017-08-01 |
| Owner |
FUTURE DIAGNOSTICS B.V. (Netherlands)
|
| Inventor |
- Swinkels, Leon Maria Jacobus Wilhelmus
- Maas, Antonius Franciscus
- Martens, Michael Franciscus Wilhelmus Cornelis
|
Abstract
Disclosed is an invention in the field of conducting an immunoassay of 25(OH) vitamin D in blood or blood components, notably serum or plasma. The invention employs a perfluoro alkyl acid, or a salt thereof,to release 25(OH) vitamin D from vitamin D binding protein. Thereafter the binding protein comprising the 25-OH vitamin D is subjected to a competitive binding assay with a labeled vitamin D compound.
IPC Classes ?
- C08F 14/26 - Tetrafluoroethene
- G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor
- G01N 33/82 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving vitamins
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6.
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RELEASE REAGENT FOR VITAMIN D
| Application Number |
NL2011050905 |
| Publication Number |
2012/091569 |
| Status |
In Force |
| Filing Date |
2011-12-27 |
| Publication Date |
2012-07-05 |
| Owner |
FUTURE DIAGNOSTICS B.V. (Netherlands)
|
| Inventor |
- Swinkels, Leon Maria Jacobus Wilhelmus
- Maas, Antonius Franciscus
- Martens, Michaël Franciscus Wilhelmus Cornelis
- Rosmalen, Franciscus Maria Anna
|
Abstract
Disclosed is an invention in the field of conducting an immunoassay of 25(OH) vitamin D in blood or blood components, notably serum or plasma. The invention employs a perfluoro alkyl acid, or a salt thereof,to release 25(OH) vitamin D from vitamin D binding protein. Thereafter the binding protein comprising the 25-OH vitamin D is subjected to a competitive binding assay with a labeled vitamin D compound.
IPC Classes ?
- C08F 14/26 - Tetrafluoroethene
- G01N 33/82 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving vitamins
- G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor
|
7.
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IMMUNOASSAY FOR FREE VITAMIN D
| Document Number |
02794831 |
| Status |
In Force |
| Filing Date |
2011-04-01 |
| Open to Public Date |
2011-10-06 |
| Grant Date |
2017-06-20 |
| Owner |
FUTURE DIAGNOSTICS B.V. (Netherlands)
|
| Inventor |
- Martens, Michael Franciscus Wilhelmus Cornelis
- Parsons, George Henry
- Rosmalen, Franciscus Maria Anna
- Swinkels, Leon Maria Jacobus Wilhelmus
|
Abstract
Disclosed is the invention to conduct immuno-adsorption of free 25(OH) vitamin D from blood or blood components, notably serum or plasma, after which the absorbed material is measured. A fluoro-alkyl surfactant is used to enhance the solubility of Vitamin D and allow the measurement of free Vitamin D. The invention thus employs a binding protein to absorb the free 25(OH) vitamin D. Thereafter the binding protein comprising the 25-OH vitamin D is subjected to a competitive binding assay with a labeled vitamin D compound, preferably radiolabeled, fluorescent labeled, luminescent labeled, biotin labeled, gold labeled or enzyme labeled. Alternatively the immunocaptured 25-OH vitamin D can be quantitated by mass spectrometry.
IPC Classes ?
- G01N 33/82 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving vitamins
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8.
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IMMUNOASSAY FOR FREE VITAMIN D
| Application Number |
NL2011050219 |
| Publication Number |
2011/122948 |
| Status |
In Force |
| Filing Date |
2011-04-01 |
| Publication Date |
2011-10-06 |
| Owner |
FUTURE DIAGNOSTICS B.V. (Netherlands)
|
| Inventor |
- Martens, Michaël Franciscus Wilhelmus Cornelis
- Parsons, George Henry
- Rosmalen, Franciscus Maria Anna
- Swinkels, Leon Maria Jacobus Wilhelmus
|
Abstract
Disclosed is the invention to conduct immuno-adsorption of free 25(OH) vitamin D from blood or blood components, notably serum or plasma, after which the absorbed material is measured. A fluoro-alkyl surfactant is used to enhance the solubility of Vitamin D and allow the measurement of free Vitamin D. The invention thus employs a binding protein to absorb the free 25(OH) vitamin D. Thereafter the binding protein comprising the 25-OH vitamin D is subjected to a competitive binding assay with a labeled vitamin D compound, preferably radiolabeled, fluorescent labeled, luminescent labeled, biotin labeled, gold labeled or enzyme labeled. Alternatively the immunocaptured 25-OH vitamin D can be quantitated by mass spectrometry.
IPC Classes ?
- G01N 33/82 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving vitamins
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