The present disclosure relates to a membrane prepared from a blend comprising i) a polysulfone, polyether sulf one or polyarylethersulfone and ii) polyvinylpyrrolidone, characterized in that the membrane is coated with polydopamine and chon-droitin. Optionally the coating further comprises heparin. The disclosure further relates to a process for producing the coated membrane, a method of increasing the selectivity of a membrane, and to a filtration/diffusion device comprising the membrane which can be used, for example, in hemodialysis applications.
The present disclosure relates to a process for producing a filtration and/or diffusion device. e.g., a capillary dialyzer or an ultrafilter, and to devices used in the process.
An apparatus for extracorporeal blood treatment comprises a control unit (100) which, during the extracorporeal blood treatment, is programmed for: computing a mass balance rate (Jsoln) of a selected solute or solutes from a solute concentration (Csoln) in dialysis fluid and/or infusion fluids, from a patient solute concentration (Cpsoln), from a fluid flow rate or rates (Qpbp, Qpre, Qpost, Qdial, Qanc) and from a filtration flow rate (Qfil) or a patient fluid removal rate (Qpfr); computing, from the computed mass balance rate (Jsoln) and from a specific energy load (Emetsoln) of each solute, an energy balance (Esoln) due to the selected solute or solutes.
A61M 1/16 - Dialysis systemsArtificial kidneysBlood oxygenators with membranes
A61M 1/34 - Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration, diafiltration
A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
A61M 60/113 - Extracorporeal pumps, i.e. the blood being pumped outside the patient’s body incorporated within extracorporeal blood circuits or systems in other functional devices, e.g. dialysers or heart-lung machines
A61M 60/279 - Peristaltic pumps, e.g. roller pumps
A61M 60/37 - Haemodialysis, haemofiltration or diafiltration
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
4.
DISPOSABLE SET AND EXTRACORPOREAL BLOOD TREATMENT APPARATUS FOR PREVENTING DEGASSING IN AN INFUSION FLUID LINE
Disposable set for an extracorporeal blood treatment apparatus including a blood circuit comprising a filtration unit, a blood withdrawal line including a blood pump tract configured to be engaged by a blood pump, a blood return line, and an infusion line extending between a first end connected to the blood withdrawal line upstream the blood pump tract, and a second end for connection to an infusion substance source: the blood pump tract is interposed between the filtration unit and the first end of the infusion line. The disposable set further comprises a pressure damper arranged towards or at the first end of the infusion line, the pressure damper being configured to prevent, or reduce an amount of, the access negative pressure to extend in the infusion line upstream the pressure damper.
A61M 39/28 - Clamping means for squeezing flexible tubes, e.g. roller clamps
A61M 60/113 - Extracorporeal pumps, i.e. the blood being pumped outside the patient’s body incorporated within extracorporeal blood circuits or systems in other functional devices, e.g. dialysers or heart-lung machines
A61M 60/279 - Peristaltic pumps, e.g. roller pumps
A61M 60/37 - Haemodialysis, haemofiltration or diafiltration
A61M 60/546 - Regulation using real-time blood pump operational parameter data, e.g. motor current of blood flow, e.g. by adapting rotor speed
5.
METHOD FOR INCREASING THE SELECTIVITY OF A MEMBRANE
The disclosure relates to a method for improving the selectivity of a membrane, specifically of a membrane comprising a blend of i) a polysulfone, polyethersulfone or polyarylethersulfone and ii) polyvinylpyrrolidone, characterized in that the membrane is coated with polydopamine and heparin in a one-step or two-step reaction or by in situ modification with polydopamine followed by coating with heparin. The disclosure further relates to a process for producing such modified membranes having an improved selectivity, and to a filtration/diffusion device comprising the membrane which can be used, for example, in hemodialysis applications.
The invention provides a first concentrate comprising lactate and calcium ions, said first concentrate having increased stability against precipitation at temperatures around +4° C., said first concentrate being useful for preparing a ready-to-use dialysis fluid by mixing said first concentrate with water and optionally a second concentrate comprising glucose, wherein that the lactate concentration Lconc (expressed in moles per litre, M) of the concentrate fulfills the conditions:
The invention provides a first concentrate comprising lactate and calcium ions, said first concentrate having increased stability against precipitation at temperatures around +4° C., said first concentrate being useful for preparing a ready-to-use dialysis fluid by mixing said first concentrate with water and optionally a second concentrate comprising glucose, wherein that the lactate concentration Lconc (expressed in moles per litre, M) of the concentrate fulfills the conditions:
a
)
L
conc
>
0.8
M
;
and
b
)
L
conc
<
(
1.9
-
0.4
×
Ca
ready
)
M
;
The invention provides a first concentrate comprising lactate and calcium ions, said first concentrate having increased stability against precipitation at temperatures around +4° C., said first concentrate being useful for preparing a ready-to-use dialysis fluid by mixing said first concentrate with water and optionally a second concentrate comprising glucose, wherein that the lactate concentration Lconc (expressed in moles per litre, M) of the concentrate fulfills the conditions:
a
)
L
conc
>
0.8
M
;
and
b
)
L
conc
<
(
1.9
-
0.4
×
Ca
ready
)
M
;
and wherein Caready is the calcium concentration of the ready-to-use dialysis fluid expressed in millimoles per litre (mM).
DWI - LEIBNIZ-INSTITUT FÜR INTERAKTIVE MATERIALIEN E.V. (Germany)
LEIBNIZ-INSTITUT FÜR POLYMERFORSCHUNG DRESDEN E.V. (Germany)
Inventor
Helmecke, Tina
Rose, Ilka
Tsurkan, Mikhail
Roth, Hannah
Maitz, Manfred
Werner, Carsten
Menda, Ralf
Rempfer, Martin
Wessling, Matthias
Abstract
The present disclosure relates to polysulfone, polyether-sulfone or polyarylethersulfone based membranes for use in extracorporeal blood treatment applications comprising a blend of (i) a polysulfone (PS), a polyethersulfone (PES) or a polyarylethersulfone (PAES); (ii) a polyvinylpyrrolidone (PVP); and (iii) a poly(styrene-alt-maleic anhydride)- copolymer which are configured for the immobilization of amine-bearing functional molecules on the surface of the membrane. The disclosure further relates to a method for producing the membranes and a filtration and/or diffusion device comprising the membrane.
B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or propertiesManufacturing processes specially adapted therefor characterised by their properties
The present application provides a dialysis fluid comprising ketone bodies such as acetoacetate, beta-hydroxybutyrate or pharmaceutically acceptable derivatives, esters and salts thereof, for use in a peritoneal dialysis therapy method of treating cancer.
A system is configured to generate a medical fluid for renal replacement therapy by on-line mixing of fluids. The system comprises a first flow path (12), a second flow 5 path (16), a first sensor (20) in the first flow path, and a second sensor (20') in the second flow path. The first and second sensors measure a composition-related parameter. The system is operable to convey at least one of the fluids to the first and second sensors in a calibration phase, and determine a conversion function for converting between a first signal of the first sensor and a second signal of the second 0 sensor, based the first and second signals during the calibration phase. In a production phase, the system is operable to control at least one pump based on converted measurement values given by operating the conversion function on measurement values in the first signal from the first sensor.
The present application provides a dialysis fluid comprising:
a) ketone bodies such as acetoacetate, beta-hydroxybutyrate or pharmaceutically acceptable derivatives, esters and salts thereof; and
b) bicarbonate ions,
for use in a dialysis therapy method of treating cancer.
Extracorporeal blood treatment systems and methods to display information related to an alarm issued during extracorporeal blood treatments. For example, when an alarm is issued, an alarm region may be depicted on a graphical user interface. The alarm region may be configured to be docked into another region of the graphical user interface to, e.g., expose an operations region, etc.
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
Synthetic membranes for the removal, isolation, or purification of substances from a liquid. The membranes include at least one hydrophobic polymer and at least one hydrophilic polymer. 5-40 wt.-% of particles having an average particles size of between 0.1 and 15 μm are entrapped. The membrane has a wall thickness of below 150 μm. Methods for preparing the membranes in various geometries, and use of the membranes for the adsorption, isolation, and/or purification of substances from a liquid are explored.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
37 - Construction and mining; installation and repair services
41 - Education, entertainment, sporting and cultural services
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Pharmaceutical preparations for the treatment of kidney
diseases; food supplements for the treatment of kidney
diseases; concentrates in solid or liquid form for
pharmaceutical use for preparing dialysis fluid; dialysis
fluid for hemodialysis; dialysis fluid for peritoneal
dialysis; pharmaceutical solutions for dialysis. Dialysis apparatus and disposable articles for dialysis
apparatus; home kidney dialysis apparatus and accessories
therefor; machines and apparatus for preparing dialysis
solutions. Installation, repair and maintenance of medical equipment,
namely, dialysis equipment and equipment used in relation to
dialysis equipment. Education services and programs, namely, live seminars,
non-downloadable webinars in the field of kidney health and
medical procedures for the treatment of kidney diseases and
kidney replacement therapies; producing DVDs in the field of
kidney health and medical procedures for the treatment of
kidney diseases and kidney replacement therapies; education
services, namely, the provision of non-downloadable videos
and interactive online training services in the field of
health and medical procedures for the treatment of kidney
diseases via a website; education and training of healthcare
professionals, namely, conferences, exhibitions and
workshops in the fields of dialysis and chronic kidney
diseases. Providing medical information on the prevention, detection,
care and management of kidney diseases via a website;
medical diagnosis and treatment of kidney diseases; medical
testing, analysis, reporting, assessment and monitoring
services relating to the treatment and management of kidney
diseases.
An apparatus for extracorporeal blood treatment comprises a control unit (100) connected to a blood pump (10) configured to deliver a blood flow rate in a blood circuit of the apparatus (1), to a diuretic pump (27) configured to deliver a flow rate (Qd) of a 5diuretic (e.g. furosemide) and to an osmotic agent pump (30) configured to deliver a flow rate (Qoa) of an osmotic agent (e.g. albumin) to be infused in the blood circuit or in the vascular system of the patient (P). The control unit (100) is configured for receiving at least one input patient parameter (e.g. blood 10pressure) and/or at least one input apparatus parameter (e.g. access pressure) and, during an extracorporeal blood treatment, to drive the diuretic pump (27) and/or the osmotic agent pump (30) as a function of said at least one input patient parameter and/or as a function of at least one input apparatus parameter, in order to15achieve an improved and better fluid removal from the patient (P).
An extracorporeal blood treatment apparatus (1) comprising a fluid circuit (6) coupled to a blood treatment unit (2), a fluid pump (9) to determine a fluid flow inside the fluid circuit (6), and a fluid temperature control device (15). A fluid warming/cooling bag (24) coupled to the fluid circuit (6) comprises a first fluid conduit (25) configured for putting a first inlet port (25a) in fluid communication with a first outlet port (25b) and a second fluid conduit (26) configured for putting a second inlet port (26a) in fluid communication with a second outlet port (26b), the first and the second fluid conduit (25, 26) being fluidically separated from each other. When the fluid warming/cooling bag (24) is accommodated in the fluid temperature control device (15), the latter simultaneously determining a heat exchange with the two fluids inside the first and second fluid conduits (25, 26) of the fluid warming/cooling bag (24).
A61M 1/16 - Dialysis systemsArtificial kidneysBlood oxygenators with membranes
A61M 1/34 - Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration, diafiltration
A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
A61M 5/44 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests having means for cooling or heating the devices or media
16.
EVALUATING INTEGRITY OF A FORWARD OSMOSIS MEMBRANE DURING CONTINUOUS FLOW
Provided herein are a control arrangement, a solution generation apparatus, and a method for evaluating an integrity of a forward osmosis (“FO”) membrane of a FO-device in a dialysis solution generation apparatus. The FO-device is configured to be used in a FO session for diluting a dialysis concentrate in a process for producing a dialysis solution. The FO-membrane separates a first side from a second side of a FO-device. The method comprises passing electrolyte solution at the first side and passing low-electrolyte solution at the second side. The method further comprises measuring conductivity of a solution generated from the second side and evaluating the integrity of the FO-membrane based on whether the measured conductivity meets conductivity criteria. The conductivity criteria include a conductivity of a solution generated from the second side with an equivalent electrolyte solution and an equivalent low-electrolyte solution using a FO-membrane that is intact or has integrity.
The present application relates to an extracorporeal blood treatment system for treating a subject. In an example, a system computing unit of the extracorporeal blood treatment system is adapted for receiving a desired blood concentration GLNb of glutamine, a desired blood concentration GLUCOSEb of glucose, and a desired blood concentration of a ketone body KETONEb. The system computing unit is adapted for controlling a blood pump and a dialysate fluid pump so that the actual concentration value GLNa of glutamine is driven towards GLNb, and the actual concentration value GLUCOSEa of glucose is driven towards Db, and the actual concentration value of ketone bodies is driven towards KETONEa.
Provided herein are a control arrangement and a method for determining a water permeability status of a forward osmosis (FO) membrane of a FO device in a dialysis fluid generation apparatus. The FO-membrane separates a feed side and a draw side of the FO device. The FO-device comprises a feed inlet port and a feed outlet port in fluid communication with the feed side, and a draw inlet port and a draw outlet port in fluid communication with the draw side. The method comprises providing a flow of pure water at the feed side and providing a flow of pure water at the draw side. The method further comprises monitoring one or more pressures indicative of a transmembrane pressure between the feed side and the draw side.
B01D 61/00 - Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltrationApparatus, accessories or auxiliary operations specially adapted therefor
C02F 1/00 - Treatment of water, waste water, or sewage
C02F 1/44 - Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis
19.
OPERATING A MEDICAL DEVICE DURING STARTUP AND SHUTDOWN
A medical device comprises a software (SW) system for execution by processor(s). The SW system defines a plurality of subsystems, including a primary subsystem and one or more secondary subsystems. Each subsystem comprises SW applications involved in the operation of the medical device during a medical procedure. The SW system, when executed by the set of processors, causes the set of processors to perform a shutdown procedure, which includes providing a shutdown notification for the secondary subsystems. The shutdown procedure also includes requesting termination of the SW applications of the primary subsystem. The shutdown procedure further includes requesting termination of the software applications of the respective secondary subsystem after the shutdown notification is received.
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
20.
DETECTING A DISRUPTION OF BLOOD RETURN IN EXTRACORPOREAL BLOOD PROCESSING
An apparatus is operated by a control system to perform blood processing in relation to a patient. The control system performs VND (Venous Needle Dislodgement) monitoring during blood processing based on a pressure signal representing return pressure in an extracorporeal blood circuit of the apparatus. The control system sets (403) an adjusted alarm limit (DLL) in relation to a pressure level (PL) at start of blood processing, and then performs (404) a first monitoring of PL in relation to DLL. When PL is below DLL, the control system generates (405) a first-type alarm and stops the blood processing. During blood processing, the control system further performs (406) a second monitoring of PL in relation to a predefined supervision limit (SL). When PL is below SL, the control system generates (407) a second-type alarm. The second monitoring makes it possible to increase awareness among supporting staff that a patient has an increased risk of suffering a VND event that may be undetected by the first monitoring.
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
21.
CONTROLLING AN APPARATUS FOR PRODUCTION OF MEDICAL FLUID FOR USE IN DIALYSIS THERAPY
A fluid preparation apparatus is configured to provide (205) medical fluid for use in dialysis therapy, by generating (204) a mixture of a base fluid and one or more concentrate fluids, each of which is stored in a respective container. A control device determines (203) a reference concentration of the concentrate fluid(s) at a reference time point, by operating (202) the apparatus to pump the concentrate fluid(s) to a sensor device for measuring a composition-related parameter. The control device estimates (206) a momentary concentration of the concentrate fluid(s) as a function of time, by use of the reference concentration and at least one calculation function for calculation of evaporative loss of water from the container(s) over time. Before or during production of the mixture, the control device adjusts (207) a mixing ratio between the base fluid and the concentrate fluid(s) based on the momentary concentration, to produce the mixture with a target composition.
Disclosed herein is a disposable set for operation with first and second concentrate containers in fluid communication with first and second concentrate container connectors. The disposable set includes a pumping cassette comprising at least a first concentrate port and a second concentrate port. The disposable cassette also includes a first concentrate line in fluid communication with the first concentrate port and a second concentrate line in fluid communication with the second concentrate port. The first concentrate line terminates at a first concentrate line connector having a first configuration for mating with the first concentrate container connector. The second concentrate line terminates at a second concentrate line connector having a second, different configuration for mating with the second concentrate container connector, such that the first concentrate line connector cannot mate with the second concentrate container connector and the second concentrate line connector cannot mate with the first concentrate container connector.
A61M 5/152 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons flexible pressurised by contraction of elastic reservoirs
C02F 1/00 - Treatment of water, waste water, or sewage
C02F 1/02 - Treatment of water, waste water, or sewage by heating
C02F 1/44 - Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis
C02F 103/02 - Non-contaminated water, e.g. for industrial water supply
23.
SYSTEMS FOR SUPPLYING MEDICAL FLUID FOR RENAL REPLACEMENT THERAPY AND METHODS OF OPERATING SUCH SYSTEMS
A system comprises a first device and a second device which establish a fluid path between a pump in the first device and a container in the second device through a valve in the second device. A control unit in the second device selectively operates the valve to open the fluid path. The second device is configured to supply a medical fluid by use of a first fluid received from the first device on the fluid path. A control unit in the first device measures fluid pressure in the fluid path and operates to, intermittently during operation of the second device, activate the pump to pump the first fluid into the fluid path and, when the fluid pressure in the fluid path indicates that the valve is closed, deactivate the pump. The first device is operable to replenish the container without being synchronized with the second device.
An apparatus for extracorporeal treatment of blood comprising a treatment unit, a blood withdrawal line, a blood return line, a preparation line and a spent dialysate line; a non-invasive blood volume sensor for determining an additional property of blood is active on a tube segment of the blood withdrawal line or of the blood return line; the sensor includes one source for directing a signal towards the blood, a plurality of detectors for receiving the signal, and a controller receiving the output signals from the detectors and determining a blood volume variation and a value of sodium concentration in the blood (NaPl) both based on the output signals. A process of determining at least one parameter and on property of blood circulating an extracorporeal blood circuit is also disclosed.
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
A61M 1/16 - Dialysis systemsArtificial kidneysBlood oxygenators with membranes
A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical solutions used in dialysis, namely dialysis
fluids, dialysis replacement fluids or dialysis
concentrates, all used in hemodialysis, hemofiltration or
hemodiafiltration.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
37 - Construction and mining; installation and repair services
41 - Education, entertainment, sporting and cultural services
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Préparations pharmaceutiques pour le traitement des maladies rénales; compléments alimentaires pour le traitement des maladies rénales; concentrés sous forme solide ou liquide à usage pharmaceutique pour la préparation de liquide de dialyse; liquide de dialyse pour hémodialyse; liquide de dialyse pour dialyse péritonéale; solutions pharmaceutiques pour dialyse.
(2) Appareils de dialyse et articles à usage unique pour les appareils de dialyse; appareils de dialyse rénale à domicile et leurs accessoires; machines et appareils pour la préparation des solutions de dialyse. (1) Services d'installation, de réparation et de maintenance d'équipements médicaux, à savoir, d'équipements de dialyse et d'équipements utilisés en relation avec des équipements de dialyse.
(2) Services et programmes d'éducation, à savoir, séminaires en direct, webinaires non téléchargeables dans le domaine de la santé rénale et des procédures médicales pour le traitement des maladies rénales et des thérapies de remplacement rénal; production de DVD dans le domaine de la santé rénale et des procédures médicales pour le traitement des maladies rénales et des thérapies de remplacement rénal; services d'éducation, à savoir, mise à disposition de vidéos non téléchargeables et de services de formation interactive en ligne dans le domaine de la santé et des procédures médicales pour le traitement des maladies rénales via un site web; services d'éducation et de formation des professionnels de santé, à savoir, conférences, expositions et ateliers dans les domaines de la dialyse et des maladies rénales chroniques.
(3) Services de mise à disposition d'informations médicales sur la prévention, la détection, les soins et la gestion des maladies rénales par le biais d'un site web; services de diagnostic médical et de traitement des maladies rénales; services de tests médicaux, d'analyse, de comptes-rendus, d'évaluation et de suivi relatifs au traitement et à la gestion des maladies rénales.
27.
ACIDIC AND ALKALINE CLEANING OF ION EXCHANGE SYSTEMS, SUCH AS WATER PURIFIERS, BY ION EXCHANGE RESIN
A water purification module includes a fluid path and a control unit. The flow path includes a cationic resin cartridge, an anionic resin cartridge in fluid communication with the cationic resin cartridge, and at least one bypass fluid path arranged to bypass one of the cationic resin cartridge and the anionic resin cartridge, while allowing water to flow to the other of the cationic resin cartridge and the anionic resin cartridge. The flow path also includes a valve arrangement comprising one or more valves configured to selectively direct water to the at least one bypass fluid path. The control unit is configured to control the valve arrangement to direct water to the at least one bypass fluid path based on a production mode of the water purification module.
A digital communication module for a self-contained medical device communication platform is disclosed herein. In an example, a digital communication module is communicatively coupled to a medical device. The digital communication module is also connected to a clinician device via a wireless proprietary network or a direct wireless link. The digital communication module receives medical device data from the medical device and determines at least some of the medical device data satisfies certain criteria. In response, the digital communication module transmits a notification message to the clinician device via the proprietary network or the direct wireless link. The notification message is indicative of the at least some of the medical device data satisfying the criteria.
H04L 67/12 - Protocols specially adapted for proprietary or special-purpose networking environments, e.g. medical networks, sensor networks, networks in vehicles or remote metering networks
29.
EXTRACORPOREAL BLOOD TREATMENT APPARATUS AND METHOD FOR MONITORING PRESSURES IN AN EXTRACORPOREAL BLOOD TREATMENT APPARATUS
An extracorporeal blood treatment apparatus, comprises: at least a pressure sensor (24, 25) located in a respective measurement site on an extracorporeal blood circuit (6, 7); an electronic control unit (23) operatively connected at least to the pressure sensor (24, 25). The electronic control unit (23) is configured to perform at least the following procedure: receiving from the pressure sensor (24, 25) a signal correlated to a measured blood pressure (P1measured, P2measured) in the measurement site; correcting the blood measured pressure (P1measured, P2measured) through a mathematical correction model to obtain a blood actual pressure (Pinlet, Poutlet) in a reference site other than the measurement site. Between the reference site and the measurement site, a circuit section and, optionally, at least one additional device (18, 27, 28) is/are positioned. The mathematical correction model is a model of a pressure drop in the circuit section and, optionally, in the additional device (18, 27, 28).
A device is disclosed for determining an access flow rate of a patient when connected to a blood treatment machine. The device performs a measurement phase in which the blood treatment machine is caused to operate in first and second operating states, where the second operating state at least differs from the first operating state by a change of flow direction of blood or treatment fluid through a dialyzer of the blood treatment machine. Based on sensor values representing a fluid property of the treatment fluid in the first and second operating states, the device computes a measurement value of comparison parameter (e.g. a ratio or a difference) that compares treatment efficiency in the first operating state to treatment efficiency in the second operating state, and determines, based on the measurement value, an estimated value of the access flow rate.
A method and a related system for providing setting parameter values to a medical apparatus to perform a medical treatment, the method comprising a remote procedure comprising the steps of providing a remote device comprising a user interface, entering setting parameter values into the remote device by the user interface, wherein the setting parameter values define a setting of the medical apparatus and are related to an identified patient and are part of a patient prescription for said identified patient. The remote procedure further comprises generating a setting signal encoding said setting parameter values. The method further comprises an acquisition procedure including providing the medical apparatus with a reader, reading the setting signal by relatively approaching the reader of the medical apparatus to the remote device, and acquiring said setting parameter values through the reading step. The medical apparatus is set based on the values of said setting parameter values.
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
(1) Solutions pharmaceutiques utilisées en dialyse, à savoir fluides de dialyse, fluides de substitution pour la dialyse ou concentrés pour la dialyse, tous étant utilisés en hémodialyse, hémofiltration ou hémodiafiltration.
34.
EVALUATING THE INTEGRITY OF A FORWARD OSMOSIS MEMBRANE USING TRANSMEMBRANE PRESSURE
Provide herein are a control arrangement and method for evaluating the integrity of a forward osmosis (FO—) membrane of a FO device in a dialysis solution generation apparatus. The FO-membrane separates a feed side and a draw side of the FO device. The FO-device comprises a feed inlet port and a feed outlet port in fluid communication with the feed side, and a draw inlet port and a draw outlet port in fluid communication with the draw side. The method comprises providing a flow of feed solution at the feed side via the feed inlet port and providing a flow of draw solution at the draw side via the draw inlet port, with an osmotic pressure at the draw side that is higher than an osmotic pressure at the feed side. Water is extracted from the feed side to the draw side to dilute the draw solution.
B01D 65/10 - Testing of membranes or membrane apparatusDetecting or repairing leaks
B01D 61/00 - Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltrationApparatus, accessories or auxiliary operations specially adapted therefor
G01M 3/26 - Investigating fluid tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors
35.
APPARATUS AND METHODS FOR EFFICIENT PRODUCTION OF DIALYSIS FLUID USING FORWARD OSMOSIS
Provided herein are an apparatus and method for producing dialysis fluid. The apparatus comprises a draw fluid path, a feed fluid path, and a forward osmosis- (FO-) unit. The FO-unit includes a feed side and a draw side separated by a FO-membrane, the feed side is included in the feed fluid path and the draw side is included in the draw fluid path. The FO-unit is configured to receive a dialysis concentrate fluid at the draw side and to receive spent dialysis fluid at the feed side. Water is transported from the spent dialysis fluid to the dialysis concentrate fluid through the FO-membrane by means of an osmotic pressure difference between the draw side and the feed side, thereby diluting the dialysis concentrate fluid into a diluted dialysis concentrate fluid and dewatering the spent dialysis fluid into a dewatered spent dialysis fluid.
A control unit of an apparatus for extracorporeal blood treatment is configured to perform a control procedure. The control procedure includes calculating parameter control values to be set during a time interval after the instant in which the control is made, on the basis of actual values and of prescription values of variation in blood volume, ultrafiltration flow rate, and concentration of sodium. The control procedure further includes imposing the parameter control values during the time interval consecutive to the instant in which the control is made such that the actual values of the variation in blood volume track the prescription values of the variation in blood volume over a predetermined treatment time. The control unit is further configured to perform a procedure for automatically estimating/calculating a target plasma conductivity and/or a target concentration of sodium in plasma to be reached at the end of the extracorporeal blood treatment.
A61M 1/16 - Dialysis systemsArtificial kidneysBlood oxygenators with membranes
A61M 1/34 - Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration, diafiltration
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
37.
SYSTEMS AND METHODS FOR PERITONEAL DIALYSIS HAVING POINT OF USE DIALYSIS FLUID PREPARATION INCLUDING MIXING AND HEATING THEREFORE
A peritoneal dialysis system includes a cycler comprising a control unit and a pump actuator. The peritoneal dialysis system also includes a disposable set operable with the cycler and in fluid communication with a source of water made suitable for peritoneal dialysis (“WFPD”) and a source of concentrate. The disposable set includes a pumping cassette comprising a pump chamber configured to be actuated by the pump actuator and a mixing container. The control unit is programmed to cause (i) the pump actuator to operate the pump chamber to pump a first amount of the WFPD to the mixing container, (ii) the pump actuator to operate the pump chamber to pump a prescribed amount of concentrate from the concentrate source to the mixing container, and (iii) the pump actuator to operate the pump chamber to pump a second amount of the WFPD to the mixing container.
A61M 5/152 - Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. by means of pistons flexible pressurised by contraction of elastic reservoirs
C02F 1/00 - Treatment of water, waste water, or sewage
C02F 1/02 - Treatment of water, waste water, or sewage by heating
C02F 1/44 - Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis
C02F 103/02 - Non-contaminated water, e.g. for industrial water supply
The present disclosure relates to devices for the on-line drying of permselective hollow fiber membranes. The present disclosure also relates to a continuous process for drying permselective hollow fiber membranes on-line using said devices.
The disclosure relates to preparing an extracorporeal blood treatment apparatus. In an example, a disposable arrangement for use in the extracorporeal blood treatment apparatus includes at least one fluid-conducting device that is configurable to define a flow circuit that extends through a blood chamber of a dialyzer. The at least one fluid-conducting device comprises connectors for connection to a vascular system of a subject during a blood treatment. The disposable arrangement also includes a sterilizing filter. The disposable arrangement is configurable to define the flow circuit to form a closed loop that includes the sterilizing filter for priming the at least one fluid-conducting device.
Medical device remote screen view methods, apparatuses, and systems are disclosed. The systems, methods, and apparatuses are configured to provide a graphical representation of a screen that is currently displayed by a medical device to provide enough context as though a clinician were physically located at a patient's bedside. In some embodiments, the medical device transmits medical data and an identifier of a displayed screen, which is populated into a corresponding user interface of a software application on a clinician device. In other embodiments, the medical device transmits images of a displayed screen, which are displayed by the software application on a clinician device.
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
G06F 9/451 - Execution arrangements for user interfaces
G06V 10/75 - Organisation of the matching processes, e.g. simultaneous or sequential comparisons of image or video featuresCoarse-fine approaches, e.g. multi-scale approachesImage or video pattern matchingProximity measures in feature spaces using context analysisSelection of dictionaries
41.
FLEXIBLE BAG FOR DIALYSIS CONCENTRATES WITH SEALED OVERPOUCH
The present invention relates to a disposable flexible bag for dialysis concentrate comprising a primary bag and an overpouch designed to ensure that the overpouch remains on the primary bag during use of the concentrate to prevent water evaporation that could lead to an out-of-specification situation towards the end of the in-use period.
Disposable set and extracorporeal blood treatment apparatus comprising a blood circuit including a filtration unit, a blood withdrawal line, a blood return line, a blood pump tract on the blood withdrawal line or on the blood return line and configured to be engaged to a blood pump of the extracorporeal blood treatment apparatus to promote blood flow in the blood circuit. The blood circuit further comprises an infusion connected to both the blood withdrawal line at a first site, and to the return line at a second site. The blood circuit is configurable in a loop recirculation circuit including the filtration unit, the blood pump tract, a part of the blood withdrawal line, a part of the blood return line and a recirculation portion of the infusion line interposed between the first site and the second site.
SSR_initSSR_init SSR_finalSSR_final SSR_finalSSR_final SSR_finalSSR_final SSR_final ) of the SSR-component in the fluid is achieved, based on the determined relationship.
An apparatus is operable to prepare water for use in medical treatment based on supply water (W1), for example tap water. The apparatus comprises a filtration device (21) and an irradiation device (22), which are connected in series to sequentially process the supply water (W1) into dechlorinated water (W1'). The filtration device (21) and the irradiation device (22) are redundant in relation to each other, by both being configured to effectively remove the chlorine in the supply water, the filtration device (21) by use of one or more activated carbon filters, and the irradiation device (22) by ultraviolet, UV, irradiation. The combination of different removal techniques in a redundant way relaxes the need for intermittent sampling and analysis of water downstream of the filtration device (21). Further, the operation of the filtration device (21) and/or the irradiation device (22) is monitorable, via the irradiation device (22), for detection of malfunction.
Provided herein is an apparatus for producing dialysis fluid including a forward osmosis unit used for diluting a dialysis concentrate for producing dialysis fluid. The FO-unit includes a FO-membrane that separates a first side from a second side. The apparatus also comprises a first flow path including a first side and a control arrangement providing priming fluid from a source to the first flow path. A return path fluidly connects an inlet port of the first side to an outlet port of the first side to allow priming fluid from the outlet port to circulate to the inlet port via the return path. The apparatus further comprises a gas collection chamber arranged in the first flow path between the first side and the return path. The gas collection chamber removes gas from first flow path. The present disclosure also relates to a method for priming a FO-unit.
A61M 1/16 - Dialysis systemsArtificial kidneysBlood oxygenators with membranes
A61M 1/26 - Dialysis systemsArtificial kidneysBlood oxygenators with membranes which are moving
B01D 61/00 - Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltrationApparatus, accessories or auxiliary operations specially adapted therefor
(1) Medical apparatus, namely, dialysis machines and disposables for use with dialysis machines, namely tubing sets, tubing and containers all sold empty.
47.
DETERMINING INTERNAL FILTRATION RATE WITHIN A CAPILLARY HEMODIALYZER
A method and a dialysis machine for draining an extracorporeal fluid circuit are disclosed herein. The dialysis machine is connected to a dialyzer and the extracorporeal fluid circuit, which includes an arterial line connectable to a patient for drawing blood from the patient and a venous line connectable to the patient for returning blood to the patient. The method includes, after treatment termination, draining remaining fluid from the extracorporeal fluid circuit through the dialyzer.
09 - Scientific and electric apparatus and instruments
Goods & Services
Computer software, namely, downloadable or resident software
for mobile devices and computerized workstations for
creating, reviewing, displaying, handling and managing
electronic medical records.
37 - Construction and mining; installation and repair services
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Technical support services, namely, troubleshooting in the
nature of repair and updating in the nature of servicing
medical equipment, namely, dialysis equipment and equipment
used in connection with dialysis equipment; services for
remote and at-home installation, adjustment and repair of
medical equipment, namely, dialysis equipment and equipment
used in connection with dialysis equipment; installation,
troubleshooting in the nature of repair and updating in the
nature of servicing medical equipment via online and
telephone support services, namely, dialysis equipment and
equipment used in connection with dialysis equipment;
services for repair and maintenance of medical equipment,
namely, dialysis equipment and equipment used in connection
with dialysis equipment, by field services which provide
local technical support. Education services and programs, namely, live seminars,
non-downloadable webinars, DVD production, all in the field
of kidney health and medical procedures for the treatment of
kidney diseases and kidney replacement therapies; education
services, namely, providing non-downloadable videos and
interactive online training services in the field of health
and medical procedures for the treatment of kidney diseases
via a website; education and training of healthcare
professionals, namely, conferences, exhibitions and
workshops in the fields of dialysis and chronic kidney
diseases. Software as a service (SaaS) services featuring software for
controlling, monitoring and managing dialysis treatment
sessions; software as a service (SaaS) services featuring
software for creating and updating specific operating modes
for dialysis apparatus; software as a service (SaaS)
services featuring software for monitoring and managing
dialysis treatment protocols; software as a service (SaaS)
services featuring software for monitoring systems for the
detection and display of dialysis treatment parameters;
software as a service (SaaS) services featuring software for
managing and analyzing data in the field of patient dialysis
monitoring; software as a service (SaaS) services featuring
software for facilitating communication, namely, enabling
patients and healthcare professionals to access, collect and
share information in the treatment of kidney diseases;
software as a service (SaaS) services for monitoring,
collecting, storing and transmitting an individual's vital
signs and other health-related information in the treatment
of kidney diseases; software as a service (SaaS) services
enabling users to receive medical diagnoses and a
consultation, prescription management, and training on
medical apparatus and therapies in the treatment of kidney
diseases; software as a service services (SaaS) for
diagnosing computer hardware problems, analyzing operational
parameters of equipment, analyzing installed applications,
remotely locating equipment and data recovery, and a search
engine for support, repair and maintenance services, all for
medical equipment, namely, dialysis-related systems. Providing medical information on the prevention, detection,
care and management of kidney diseases via a website;
medical diagnosis, treatment, testing, analysis, reporting,
assessment and monitoring services relating to the treatment
and management of kidney diseases.
An extracorporeal blood treatment apparatus (1) has a filtration unit (2), a blood circuit (6), and a main infusion line (9) connected to a blood withdrawal line (6a) to infuse a solution into blood. A main infusion pump (11) causes the infusion solution I to flow from an infusion fluid source (10) to the blood withdrawal line, and an inactivated condition, wherein the main infusion pump (11) is inactive; a concentrate sensor (12) is placed on the blood withdrawal line between an injection point (9a) and the filtration unit (2) for monitoring the concentration of a substance. A control unit (13), in the first operating condition, activates the main infusion pump (11) and acquires the signal from the concentrate sensor (12) to determine the concentration of the substance into blood infused with the infusion solution, and, in the second operating condition, inactivates the main infusion pump (11) and acquires the signal to determine the concentration of the substance when no infusion solution I is infused into the blood.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
37 - Construction and mining; installation and repair services
41 - Education, entertainment, sporting and cultural services
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Pharmaceutical preparations for the treatment of kidney disease; dietary supplements for the treatment of kidney disease; Concentrates in solid or liquid form for pharmaceutical use for preparing dialysis fluid; Pharmaceutical solutions used in dialysis, namely, dialysis fluid for hemodialysis; Pharmaceutical solutions used in dialysis, namely, dialysis fluid for peritoneal dialysis; pharmaceutical solutions for dialysis Dialysis machines and disposable medical devices for use in dialysis machines; home kidney dialysis equipment and accessories therefor; machines and apparatus for preparing dialysis solutions Installation, repair and maintenance services of medical equipment, namely dialysis equipment and equipment used in connection therewith Education services and programs, namely, providing live seminars and non-downloadable webinars in the field of renal healthcare and medical procedures for the treatment of kidney disease and renal replacement therapies; production of dvds in the field of renal healthcare and medical procedures for the treatment of kidney disease and renal replacement therapies; educational services, namely, providing non-downloadable videos and interactive on-line training services in the field of healthcare and medical procedures for the treatment of kidney disease via a website; health care professional education and training services, namely, conferences, exhibitions and workshops in the fields of dialysis and chronic kidney disease Providing medical information about the prevention, detection, care and management of kidney disease via a website; medical diagnosis and treatment of kidney disease; medical testing, analysis, reporting, assessment and monitoring services relating to the treatment and management of kidney disease
A control unit of an apparatus for extracorporeal blood treatment is configured to perform a control procedure comprising: calculating parameter control values to be set during a time interval after the instant in which the control is made, on the basis of actual values and of prescription values of variation in blood volume, ultrafiltration flow rate, concentration of sodium and/or potassium and heart rate or variation of heart rate of the patient; imposing the parameter control values during the time interval consecutive to the instant in which the control is made such that the actual values of the variation in blood volume track the prescription values of the variation in blood volume over a predetermined treatment time and the actual values of the heart rate or variation of heart rate track the prescription values of the heart rate or variation of heart rate over the predetermined treatment time.
An apparatus for extracorporeal blood treatment comprises an extracorporeal blood circuit configured for connection either to a vascular access of a patient (P) or to a blood circuit of a high blood flow rate machine (36). A control unit (100) is configured for checking the connection of the extracorporeal blood circuit by performing the following procedure: receiving a measured pressure from a pressure sensor (25, 26); detecting if the extracorporeal blood circuit is connected to the vascular access of the patient (P) or to the blood circuit of the high blood flow rate machine (36) by performing an analysis of the measured pressure or of a parameter correlated to the measured pressure; issuing a signal if the connection to the vascular access of the patient (P) and/or the connection to the blood circuit of the high blood flow rate machine (36) is detected.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
11 - Environmental control apparatus
Goods & Services
Pharmaceutical and sanitary preparations for the treatment
of kidney diseases; food supplements for the treatment of
kidney diseases; concentrates in solid or liquid form for
pharmaceutical use for preparing dialysis fluid; dialysis
fluid for hemodialysis; dialysis fluid for peritoneal
dialysis; pharmaceutical solutions for dialysis. Dialysis apparatus and disposable articles for dialysis
apparatus; home kidney dialysis apparatus and accessories
therefor; machines and apparatus for preparing dialysis
solutions. Water purifying apparatus comprising a disinfection system,
a reverse osmosis medical system, a water distribution
system and accessories therefor, all used in the context of
dialysis treatment.
09 - Scientific and electric apparatus and instruments
Goods & Services
Downloadable computer software for controlling, monitoring
and managing dialysis treatment sessions, for managing and
analyzing dialysis patient data and dialysis treatment
protocols, and for detecting and displaying dialysis
treatment parameters; downloadable software for creating and
updating specific operating modes for dialysis machines;
downloadable software in the nature of a mobile application
for facilitating communication, namely, to enable patients
and healthcare professionals to access, collect and share
information, vital signs and other health information in the
treatment of kidney diseases; downloadable software in the
nature of a mobile application enabling users to receive
medical diagnoses and counseling, manage prescriptions, and
training on medical apparatus and therapies in the treatment
of kidney diseases; downloadable computer software and a
mobile application for diagnosing computer hardware
problems, analyzing the operational parameters of equipment,
analyzing installed applications, remote location of
equipment and data recovery, and a search engine for
support, repair and maintenance services, all applying to
dialysis systems.
Extracorporeal blood treatment systems and methods to display graphical user interfaces displaying a plurality of fluids areas, each including a flow rate, and displaying adjustment notifications proximate one or more fluid areas. For example, when a user adjusts a flow rate to a limit, one or more notifications may be displayed proximate other flow rates that may be adjusted to modify the limit.
A61M 1/34 - Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration, diafiltration
A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
G06F 3/04817 - Interaction techniques based on graphical user interfaces [GUI] based on specific properties of the displayed interaction object or a metaphor-based environment, e.g. interaction with desktop elements like windows or icons, or assisted by a cursor's changing behaviour or appearance using icons
G06F 3/0482 - Interaction with lists of selectable items, e.g. menus
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
58.
MEMBRANE WITH IMMOBILIZED ANTICOAGULANT AND PROCESS FOR PRODUCING SAME
The present disclosure relates to an anticoagulant-coated microporous hollow fiber membrane showing reduced thrombogenicity. The disclosure further relates to a method for producing the membrane and a filtration and/or diffusion device comprising the membrane.
B01D 67/00 - Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or propertiesManufacturing processes specially adapted therefor characterised by their properties
The present disclosure relates to devices and processes for the production of hollow fiber membrane bundles. The bundles are used for the manufacture of filtration and/or diffusion devices, e.g., capillary dialyzers.
A disposable circuit for extracorporeal blood treatment comprising a filtration unit (2) and a blood circuit (6, 7) with a blood withdrawal line (6) and a blood return line (7), said blood withdrawal line (6) and said blood return line (7) being designed to be connected to a patient cardiovascular system, wherein the blood withdrawal line (6) and the blood return line (7) are provided with an arterial connector (40) and a venous connector (41) detachably connected to a vascular access device of a patient; at least one fluid line (15, 21, 25, 42; 42a) is connected to the blood circuit (6, 7) and the disposable circuit further comprises a first auxiliary connector (51, 53, 55, 57, 59) and a second auxiliary connector (50, 52, 54, 56, 58) arranged either on the blood circuit (6, 7) or on the fluid line (15, 21, 25, 42; 42a), and configured to be removably connected with the arterial connector (40) and the venous connector (41) in a recirculation configuration so as to define a closed circuit allowing fluid recirculation.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical solutions used in dialysis, namely, dialysis fluids, dialysis substitution fluids or concentrates, all being for use in hemodialysis, hemofiltration or hemodiafiltration
The present disclosure relates to semipermeable membranes which are suitable for blood purification, e.g. by hemodialysis, which have an increased ability to remove larger molecules while at the same time effectively retaining albumin. The membranes are characterized by a molecular retention onset (MWRO) of between 9.0 kD and 14.5 kD and a molecular weight cut-off (MWCO) of between 55 kD and 130 kD as determined by dextran sieving curves and can be prepared by industrially feasible processes excluding a treatment with salt before drying. The invention therefore also relates to a process for the production of the membranes and to their use in medical applications.
A container for warming fluids comprises an inlet port, an outlet port, a fluid conduit configured for fluidly communicating the inlet and outlet ports, and deflection sections. The fluid conduit has a non-constant maximum width in a direction of fluid flow through the fluid conduit. The deflection sections further comprise an entry section and an exit section, each respective exit section being arranged downstream, in the direction of fluid flow, from each respective entry section. The maximum width of the fluid conduit decreases along the direction of fluid flow through the entry section over a first distance and the maximum width of the fluid conduit increases along the direction of fluid flow through the exit section over a second, different distance. A blood treatment apparatus including the above-described container is also provided.
F28F 13/08 - Arrangements for modifying heat transfer, e.g. increasing, decreasing by affecting the pattern of flow of the heat-exchange media by varying the cross-section of the flow channels
A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
64.
Medical equipment, an authentication server and methods for authorizing a user access to an equipment via an equipment user interface
The present disclosure relates to methods for authorizing user access to medical equipment via an equipment user interface. In an example, the method comprises, storing an authority public key of an authority asymmetric key pair and providing, to a user via an equipment user interface, an authorization challenge indicative of an equipment public key of a temporary equipment asymmetric key pair generated in medical equipment. The method further comprises receiving from the equipment user interface, a response code comprising validity information encrypted using a shared key derivable from the authority private key of the authority asymmetric key pair and the provided equipment public key, and authorizing the user access to the medical equipment, upon the validity information decrypted using the same shared key but derived in the medical equipment using the stored authority public key and an equipment private key of the temporary equipment asymmetric key pair, being valid.
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
37 - Construction and mining; installation and repair services
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Services d'assistance technique, à savoir, dépannage sous la forme de réparation et mise au point sous la forme d'entretien des équipements médicaux, à savoir, les équipements de dialyse et les équipements utilisés dans le cadre des équipements de dialyse; services d'installation, de réglage et de réparation à distance et à domicile des équipements médicaux, à savoir, les équipements de dialyse et les équipements utilisés dans le cadre des équipements de dialyse; installation, dépannage sous la forme de réparation et mise au point sous la forme de maintenance des équipements médicaux via des services d'assistance en ligne et par téléphone, à savoir, des équipements de dialyse et des équipements utilisés en relation avec des équipements de dialyse; services de réparation et de maintenance d'équipements médicaux, à savoir, d'équipements de dialyse et d'équipements utilisés en relation avec des équipements de dialyse, par des services sur le terrain qui fournissent une assistance technique locale.
(2) Services et programmes d'éducation, à savoir, séminaires en direct, webinaires non téléchargeables, production de DVD, tous dans le domaine de la santé rénale et des procédures médicales pour le traitement des maladies rénales et des thérapies de remplacement rénal; services d'éducation, à savoir, mise à disposition de vidéos non téléchargeables et services de formation interactive en ligne dans le domaine de la santé et des procédures médicales pour le traitement des maladies rénales via un site web; services d'éducation et de formation des professionnels de santé, à savoir, conférences, expositions et ateliers dans les domaines de la dialyse et des maladies rénales chroniques.
(3) Services de logiciels en tant que service (saas) comprenant des logiciels pour le contrôle, la surveillance et la gestion des séances de traitement par dialyse; services de logiciels en tant que service (saas) comprenant des logiciels pour la création et la mise à jour de modes de fonctionnement spécifiques pour les appareils de dialyse; services de logiciels en tant que service (saas) comprenant des logiciels pour la surveillance et la gestion des protocoles de traitement par dialyse; services de logiciels en tant que service (saas) comprenant des logiciels pour des systèmes de surveillance pour la détection et l'affichage de paramètres de traitement par dialyse; services de logiciels en tant que service (saas) comprenant des logiciels pour la gestion et l'analyse de données dans le domaine de la surveillance des patients dialysés; services de logiciels en tant que service (saas) comprenant des logiciels facilitant la communication, à savoir, permettant aux patients et aux professionnels de santé d'accéder, de collecter et de partager des informations dans le cadre du traitement des maladies rénales; services de logiciels en tant que service (saas) permettant de surveiller, de collecter, de stocker et de transmettre les signes vitaux d'un individu et d'autres informations relatives à la santé dans le cadre du traitement des maladies rénales; services de logiciels en tant que service (saas) permettant aux utilisateurs de recevoir un diagnostic médical et une consultation, une gestion des prescriptions, et une formation sur les appareils médicaux et les thérapies dans le cadre du traitement des maladies rénales; services de logiciels en tant que service (saas) pour le diagnostic des problèmes de matériel informatique, l'analyse des paramètres opérationnels des équipements, l'analyse des applications installées, la localisation à distance des équipements et la récupération de données, et un moteur de recherche pour les services d'assistance, de réparation et de maintenance, le tout pour les équipements médicaux, à savoir, les systèmes liés à la dialyse.
(4) Services de mise à disposition d'informations médicales sur la prévention, la détection, les soins et la gestion des maladies rénales par le biais d'un site web; services de diagnostic médical, de traitement, de test, d'analyse, de comptes-rendus, d'évaluation et de suivi relatifs au traitement et à la gestion des maladies rénales.
09 - Scientific and electric apparatus and instruments
Goods & Services
(1) Logiciel informatique téléchargeable pour le contrôle, la surveillance et la gestion des séances de traitement par dialyse, pour la gestion et l'analyse des données des patients dialysés et des protocoles de traitement par dialyse, et pour la détection et l'affichage des paramètres de traitement par dialyse; logiciel téléchargeable pour la création et la mise à jour de modes opératoires spécifiques pour les machines de dialyse; logiciel téléchargeable sous forme d'application mobile pour faciliter la communication, à savoir permettre aux patients et aux professionnels de santé d'accéder, de recueillir et de partager des informations, des signes vitaux et d'autres informations sur la santé dans le traitement des maladies rénales; logiciel téléchargeable sous forme d'application mobile permettant aux utilisateurs de recevoir un diagnostic médical et une consultation, une gestion des prescriptions, et une formation sur les appareils médicaux et les thérapies dans le cadre du traitement des maladies rénales; logiciel informatique téléchargeable et application mobile permettant de diagnostiquer les problèmes de matériel informatique, d'analyser les paramètres opérationnels de l'équipement, d'analyser les applications installées, de localiser à distance l'équipement et la récupération de données, et un moteur de recherche pour les services d'assistance, de réparation et d'entretien, tous s'appliquant aux systèmes de dialyse.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
11 - Environmental control apparatus
Goods & Services
(1) Préparations pharmaceutiques et hygiéniques pour le traitement des maladies rénales; compléments alimentaires pour le traitement des maladies rénales; concentrés sous forme solide ou liquide à usage pharmaceutique pour la préparation de liquide de dialyse; liquide de dialyse pour hémodialyse; liquide de dialyse pour dialyse péritonéale; solutions pharmaceutiques pour dialyse.
(2) Appareils de dialyse et articles à usage unique pour les appareils de dialyse; appareils de dialyse rénale à domicile et leurs accessoires; machines et appareils pour la préparation des solutions de dialyse.
(3) Appareils de purification d'eau comprenant un système de désinfection, un système médical d'osmose inversée, un système de distribution d'eau et leurs accessoires, tous étant utilisés dans le cadre de traitement par dialyse.
68.
APPARATUS FOR EXTRACORPOREAL TREATMENT OF BLOOD AND PROCESS OF CALCULATING SET FLOW RATES IN A MEDICAL APPARATUS FOR EXTRACORPOREAL TREATMENT OF BLOOD
A CRRT apparatus comprising a control unit configured to execute a flow-rate setup procedure by receiving a patient prescription comprising clinical prescription parameters, by allowing entry of a set value for a prescribed dialysis dose (Dset) to be delivered, and of a target value for a parameter (nNBL; CpHCO3_pat) indicative of a steady state acid-base balance in the blood of the patient who has to undergo a CRRT blood treatment, and by determining operating parameters calculating a set value of relevant fluid flow rates including one or more of a fluid flow rate (Qcit) through the anticoagulant infusion line, a fluid flow rate (QPBP) through the PBP infusion line, a fluid flow rate (Qrep_pre) through the pre-dilution infusion line, a fluid flow rate (Qrep_post) through the post-dilution infusion line, a fluid flow rate (QHCO3) through the post-dilution bicarbonate infusion line, a fluid flow rate (Qca) through the ion balancing infusion line, a blood fluid flow rate (Qb) through the extracorporeal blood circuit, a fluid flow rate (Qdial) through the dialysis liquid supply line, and a fluid flow rate (Qeff) through the effluent fluid line, wherein calculating the set value of the fluid flow rates is based at least on the set value of the prescribed dialysis dose (Dset) and on the target value for the parameter (nNBL; CpHCO3_pat) indicative of a steady state acid-base balance in the blood.
A61M 1/16 - Dialysis systemsArtificial kidneysBlood oxygenators with membranes
A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
A61M 60/113 - Extracorporeal pumps, i.e. the blood being pumped outside the patient’s body incorporated within extracorporeal blood circuits or systems in other functional devices, e.g. dialysers or heart-lung machines
A61M 60/279 - Peristaltic pumps, e.g. roller pumps
A61M 1/34 - Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration, diafiltration
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 20/17 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients delivered via infusion or injection
The present disclosure relates to a spinning beam for producing hollow fiber membranes in a phase inversion process, and to a process using the spinning beam.
D01D 5/24 - Formation of filaments, threads, or the like with a hollow structureSpinnerette packs therefor
D01F 6/56 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from mixtures of polymers obtained by reactions only involving carbon-to-carbon unsaturated bonds as major constituent with other polymers or low-molecular-weight compounds of polymers of cyclic compounds with one carbon-to-carbon double bond in the side chain
D01F 6/94 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from mixtures of polycondensation products as major constituent with other polymers or low-molecular-weight compounds of other polycondensation products
D01D 4/06 - Distributing spinning solution or melt to spinning nozzles
Medical apparatus, namely, dialysis machines and disposables for use with dialysis machines, namely tubing sets, tubing and containers all sold empty..
A peritoneal dialysis (“PD”) system includes a PD machine including a housing, a PD fluid pump housed by the housing, a plurality of PD fluid lines, and a plurality of PD fluid line connectors positioned and arranged at the housing to accept distal ends of the PD fluid lines to perform a disinfection sequence. The PD system also includes a disinfection unit including a disinfection unit housing, a PD fluid line connector positioned and arranged at the disinfection unit housing for receiving one of the PD fluid lines of the PD machine for the disinfection sequence, a line extending from the disinfection unit housing for connecting to one of the PD fluid line connectors of the PD machine for the disinfection sequence, and a disinfection fluid pump housed by the disinfection unit for pumping disinfection fluid during the disinfection sequence.
A peritoneal dialysis (“PD”) system includes a PD fluid pump, a disinfection loop including the PD fluid pump, the disinfection loop including PD fluid used for disinfecting the disinfection loop, and an acid solution source positioned and arranged to supply an acid solution to the disinfection loop during disinfection using the PD fluid. The disinfection loop includes an airtrap and a pressure sensor positioned and arranged to sense PD fluid pressure during disinfection, the pressure sensor outputting to a control unit, the control unit configured to open at least one gas valve located along at least one gas line leading to an upper portion of the airtrap when the PD fluid pressure reaches or exceeds a threshold PD fluid pressure due to gas formation caused by mixing the acid solution with the PD fluid.
A device (100) for disinfecting a catheter (302), and a method thereof is described. The device (100) comprises a stem (102), and an expandable member (104) fixed at a front portion of the stem (102). The expandable member (104) is wetted with a disinfectant. A sheath assembly (106) houses the stem (102) and the expandable member (104), and includes a front end (106-1) and a plurality of slots (108) present near the front end (106-1). The slots (108) allow for outward expansion of the expandable member (104) when the expandable member (104) is pushed towards the front end (106-1) by operating the stem (102). When the sheath assembly (106) is inserted within the catheter (302) and the expandable member (104) is brought outward by pushing through the stem (102), the expandable member (104) comes in contact with inner surface of the catheter (302), thereby disinfecting the catheter (302).
Medical apparatus and instruments for use in extracorporeal
blood treatment; medical devices, namely blood tubing sets
used on machines for hemodialysis, hemofiltration,
hemodiafiltration and ultrafiltration treatment; medical
apparatus and instruments for use in extracorporeal blood
treatment, namely, disposable sets used during hemodialysis,
hemofiltration, hemodiafiltration and ultrafiltration
treatment; medical blood tubing sets; dialyzers, hemofilters
and ultrafilters.
77.
SYSTEM AND METHOD FOR PROVIDING WATER FOR USE IN DIALYSIS
A water supply system (12) is operable to extract liquid water, EW, from waste fluid, WF, generated by a dialysis system and to provide the liquid water for use by the dialysis system. The water supply system (12) comprises a dehumidifier sub-system (20) and a humidifier sub-system (30). A gas stream is circulated between the sub-systems (20, 30) and is alternately humidified and dehumidified. The liquid water is extracted from the gas stream by the dehumidifier sub-system (20). The humidifier sub-system (30) comprises a membrane distillation unit (31) with a feed side (31A) and a draw side (31B) separated by a hydrophobic membrane (31'). The waste fluid is supplied on the feed side (31A) and the gas stream is supplied on the draw side (31B), and water vapor is transported from the waste fluid through the membrane (31') via a difference in partial water vapor pressure between the feed and draw sides (31A, 31B).
A dialysis system comprises a supply sub-system (4), a storage sub-system (5), a treatment sub-system (6), and a control device (7). The supply sub-system (4) is arranged to supply a fluid to the storage sub-system (5) and comprises a heating device (42) for heating the fluid. The storage sub-system (5) comprises a non-heated reservoir (50) for receiving the fluid from the supply sub-system (4). The treatment sub-system (6) is configured to obtain the fluid from the storage sub-system (5) for use in dialysis treatment. The control device (7) operates the supply sub-system (4) to perform a sequence of fluid supply cycles causing a sequence of time-separated boluses of the fluid to be supplied to the reservoir (50), with each fluid supply cycle being assigned a target temperature and comprising a predefined number of boluses. The supply sub- system (4) is operated to achieve, through the predefined number of boluses, the target temperature of the fluid in the reservoir (50) for the respective fluid supply cycle.
The present disclosure relates to a center fluid distributor for a multi-fiber spinneret for producing hollow fiber membranes in a phase inversion process.
A computer system is configured to implement a method of estimating residual renal function in a dialysis patient based on data for two consecutive treatment sessions of intermittent dialysis therapy. The computer system obtains first and second blood concentration values (C1, C2) for a substance, e.g. urea, creatinine, at a start and an end of a first treatment session, and a third blood concentration value (C3) at a start of a second treatment session. The computer system also obtains time points (t1, t2, t3) for the start and the end of the first treatment session and the start of the second treatment session. The computer system then estimates the residual renal function as a function of the first, second, and third concentration values (C1, C2, C3), and the time points (t1, t2, t3). The method obviates the need to include data representing collection of urine from the patient.
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
82.
CONFIGURATION OF A DIALYSIS MACHINE FOR EXTRACORPOREAL BLOOD THERAPY
A dialysis machine for extracorporeal blood therapy is configured to interface with a disposable blood line that is available in at least two different sizes. A memory in the dialysis machine is arranged to store configuration data that associates the different sizes of the blood line with a respective predefined limit value of fluid removal when the dialysis machine is operated by a controller to perform extracorporeal blood therapy. The controller is configured to execute a configuration procedure (400), which comprises obtaining (402) size data indicative of a selected size of the blood line for use in the extracorporeal blood therapy in relation to a patient; determining (403), by use of the configuration data and based on the selected size, a maximum rate of said fluid removal from blood, and configuring (404) the dialysis machine to maintain the fluid removal below the maximum rate during the extracorporeal blood therapy.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
A61M 1/16 - Dialysis systemsArtificial kidneysBlood oxygenators with membranes
A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
A61M 1/34 - Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration, diafiltration
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Pharmaceutical solutions used in dialysis; pharmaceutical solutions used for the treatment of renal insufficiency, in particular for peritoneal dialysis, hemodialysis, hemofiltration or hemodiafiltration Downloadable software for medical use related to the dialysis treatment of renal insufficiency; resident and downloadable operating software for machines for kidney treatment; downloadable software in the nature of a mobile application to facilitate communication, namely, allowing patients and healthcare professionals to access, collect and share information in the treatment of kidney disease Medical apparatus and instruments for the treatment of renal insufficiency; medical apparatus and instruments for extracorporeal blood treatment; disposable medical devices for use in extracorporeal blood treatment, namely, tubing sets and dialyzers; blood treatment apparatus, namely, dialysis machines; disposable medical devices for use in dialysis machines, namely, tubing sets, filters and containers
84.
STATUS ASSESSMENT OF AN INDIVIDUAL UNDERGOING PERITONEAL DIALYSIS
A test method determines at least one status parameter of an individual undergoing peritoneal dialysis. The status parameter(s) may include a transport property of the peritoneum, a tonicity, or a residual volume. The test method includes receiving first data indicative of a flow rate as a function of time of a treatment fluid into and out of a peritoneal cavity during a test procedure, and second data comprising measured data samples representing a concentration of one or more solutes in the treatment fluid at time points during the test procedure. The test method also includes computing, based on the first data and by use of a transport model for a peritoneal membrane, estimated data samples representing the concentration of the one or more solutes in the treatment fluid at the time points and determining the status parameter(s) as a function of the measured data samples and the estimated data samples.
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
The present invention relates to a platform (200) for mounting devices. The platform (200) comprises a frame (202) made of one or more arms (204) comprising through holes (206) present near edges of the arms (204), and a plurality of support members (208) configured to support the frame (202) near the edges, each support member (208) including a hollow shaft (210) having internal threads passing via the through holes (206). The platform (200) includes a plurality of spacers (212), each spacer (212) being disposed on the through hole (206) and comprising a bottom surface (212-1) having a profile corresponding to a curvature of the frame (202), and a plurality of threaded plugs (214), each threaded plug (214) passing through the spacer (212) and the through hole (206). The threaded plug (214) is secured with the internal threads of the hollow shaft (210) positioned above the support member (208).
A61G 12/00 - Accommodation for nursing, e.g. in hospitals, not covered by groups , e.g. trolleys for transport of medicaments or foodPrescription lists
Medical apparatus and instruments for use in extracorporeal blood treatment; apparatus for hemodialysis, hemofiltration, hemodiafiltration and ultrafiltration treatment in the nature of blood tubing sets; medical apparatus and instruments for use in extracorporeal treatment namely disposable blood tubing sets used during hemodialysis, hemofiltration, hemodiafiltration and ultrafiltration treatment; medical blood tubing sets; dialyzers, hemofilters and ultrafilters..
87.
APPARATUS FOR EXTRACORPOREAL BLOOD TREATMENT AND METHOD FOR ADMINISTERING NUTRITIONAL PRODUCTS IN AN APPARATUS FOR EXTRACORPOREAL BLOOD TREATMENT
An apparatus for extracorporeal blood treatment for chronic therapy comprises a nutritional bag (33) containing a nutritional solution, a weighing device (36) configured to determine a weight (W) of the nutritional bag (33), a nutritional line (34) for infusing the nutritional solution into either a blood return line (7) or into the patient vascular system. An ultrafiltration device (30) is configured to achieve a fluid removal from the patient through a semi- permeable membrane (5) of a filtration unit (2) and a sensor (31, 32) is configured to determine an ultrafiltration rate (UFR). A control unit (100) connected to the ultrafiltration device (30), to the weighing device (33) and to the sensor (31, 32) is programmed for receiving a patient prescription and for controlling the ultrafiltration device (30) to achieve the patient prescription based on the weight (W) and on ultrafiltration rate (UFR).
A system for peritoneal dialysis is operated, according to a measurement method, to supply a first fluid (F1) to a peritoneal cavity, PC, extract a first amount (V1) of fluid from the PC while leaving an intraperitoneal amount of fluid in the PC, and measure a first value of a concentration-related parameter of the thus-extracted fluid. The system is then operated to supply a second amount (V2) of a second fluid (F2) to form a mixture with the intraperitoneal amount of fluid in the PC, extract a third amount (V3) of the mixture from the PC, and measure a third value of the parameter of the thus-extracted mixture. The second fluid (F2) has a second value of the parameter and differs in composition from the first fluid (F1). The use of such a second fluid (F2) enables the intraperitoneal amount to be determined, with high accuracy, based on the second amount (V2) and the first, second and third values.
(1) Appareils et instruments médicaux utilisés pour le traitement extracorporel du sang; dispositifs médicaux, à savoir ensemble de kits à sang utilisés sur les machines de traitement par hémodialyse, hémofiltration, hémodiafiltration et ultrafiltration; appareils et instruments médicaux utilisés pour le traitement extracorporel du sang à savoir kits jetables utilisés pendant un traitement d'hémodialyse, d'hémofiltration, d'hémodiafiltration et d'ultrafiltration; ensemble de tubes médicaux; dialyseurs, hémofiltres et ultrafiltres.
90.
ULTRAFILTRATION CONTROL IN EXTRACORPOREAL BLOOD PROCESSING
A control system operates (201) an apparatus for extracorporeal blood processing to extract, process and return the blood of an individual while removing fluid from the blood in accordance with a set value for ultrafiltration rate, UFR. The control system further obtains (202) sensor data representing one or more physiological parameters of the individual, and intermittently performs an optimization procedure (203) to generate the set value based on the sensor data. The optimization procedure comprises: evaluating (203A) the sensor data for detection of a limiting physiological status, LPS, sequentially controlling (203B) the apparatus in accordance with a test sequence of UFRs until the LPS is detected for a current UFR, and updating (203C) the set value based on the current UFR for use in operating the apparatus subsequent to the optimization procedure. The control system may perform a series of temporally separated optimization procedures during a treatment session to adapt the UFR to the individual.
09 - Scientific and electric apparatus and instruments
Goods & Services
Computer software, namely, downloadable and pre-installed software for mobile devices and computer workstations for electronic medical records creation, review, displaying, manipulation and management
A medical fluid system includes a medical fluid pump configured to pump a medical fluid; electronics associated with the medical fluid pump or with other components of the medical fluid system; a thermoelectric heater positioned and arranged to heat medical fluid pumped by the medical fluid pump, the thermoelectric heater including a heated side and a cooled side; a heat exchanger through which medical fluid pumped by the medical fluid pump is heated, the heat exchanger positioned and arranged so as to be in thermal communication with the heated side of the thermoelectric heater; and a mounting plate, the electronics supported by the mounting plate, the mounting plate positioned and arranged so as to be in thermal communication with the cooled side of the thermoelectric heater.
A61M 1/16 - Dialysis systemsArtificial kidneysBlood oxygenators with membranes
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
A system for generating a medical fluid for renal replacement therapy is operated by a control device according to a method. In the method, a first pump (P1) is operated to convey a first fluid (F1) from a first container (3a), arranged on a first scale (2a), into a supply path (4a), and a second pump (P2) is operated to convey a second fluid (F2) from a second container (3b), arranged on a second scale (2b), into the supply path (4a), to generate a mixture therein. The speed of at least one of the pumps (P1, P2) is adjusted until a sensor (22) measures a target value of a composition-related parameter. A relation between weight changes of the first and second scales (2a, 2b) is determined while the sensor (22) measures the target value. The medical fluid is then generated in the supply path (4a), by the pumps (P1, P2) being operated, based on signals (S1, S2) from the scales (2a, 2b), to achieve said relation. The supply path (4a) may be disposable, and the sensor (22) may be re-usable and arranged in a bypass path (20).
A control device (20) performs a method to generate control signals (23) for a dialysis machine (2a; 2), which is configured to perform peritoneal dialysis, PD, treatment comprising one or more fluid exchange cycles in relation to a peritoneal cavity of a patient, to cause a transport of fluid and solutes through its peritoneal membrane. The method comprises: obtaining a target value (22) of a treatment parameter for the PD treatment, obtaining a transport property of the peritoneal membrane, and configuring a transport model by use of said at least one transport property. The transport model defines the transport of fluid and solutes through the 0 peritoneal membrane as a function of control parameters (21') for the PD treatment. The method further comprises: evaluating the transport model to determine set values of the control parameters (21') to achieve the target value (22), and generating the control signals (23) in correspondence with the set values.
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
A61M 1/16 - Dialysis systemsArtificial kidneysBlood oxygenators with membranes
95.
RENAL FAILURE THERAPY SYSTEMS HAVING REDUCED TIME BETWEEN TREATMENTS
A renal failure therapy system includes a fresh dialysis fluid tube having a connector for connecting to a dialyzer, a spent dialysis fluid tube having a connector for connecting to the dialyzer, a dialysis fluid circuit including a fresh dialysis fluid line, a spent dialysis fluid line, at least one of (i) a first disinfection device positioned between the fresh dialysis fluid line and the fresh dialysis fluid tube, or (ii) a second disinfection device positioned between the spent dialysis fluid line and the spent dialysis fluid tube and recirculation circuitry extending to a first machine connector for mating with the connector of the fresh dialysis fluid tube during disinfection and a second machine connector for mating with the connector of the spent dialysis fluid tube during disinfection. The system also includes a control unit configured to cause the first and second disinfection devices to be energized during the disinfection.
A peritoneal dialysis system includes a cycler, a disposable set operable with the cycler and including a patient line and a drain line, one of (i) a water purifier for supplying purified water for mixing to form fresh dialysis fluid at the disposable set, (ii) at least one fresh dialysis fluid container provided as part of the disposable set for supplying fresh dialysis fluid, or (iii) a dialysis fluid preparation unit configured to supply fresh dialysis fluid to the disposable set, and at least one flow path insulator provided at the cycler, the water purifier, the dialysis fluid preparation unit, and/or along the drain line. The flow path insulator is configured to separate used dialysis fluid flowing along the drain line into flow segments to limit any current flowing from the patient to a drain.
The present disclosure relates to a dialyzer comprising a bundle of semipermeable hollow fiber membranes which is suitable for blood purification, wherein the dialyzer has an increased ability to remove larger molecules while at the same time it is able to effectively remove small uremic toxins and efficiently retain albumin and larger proteins. The invention also relates to using said dialyzer in hemodialysis.
An optical detection apparatus is arranged to detect particles in a fluid flowing through a tubing portion of transparent or translucent material. The apparatus comprises a holder for the tubing portion; a light emitting device configured to irradiate a target volume inside the tubing portion when arranged in the holder; and at least one light receiving device configured to receive light from the target volume when irradiated by the light emitting device and generate one or more time-dependent output signals indicative of the received light. A computation device is configured to determine a parameter indicative of temporal variability in the one or more time-dependent output signals and estimate the density based on the parameter, which has been found to be robust to structural differences between tubings and allows the apparatus to be deployed without calibration.
A61B 5/145 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
99.
SYSTEM, METHODS, AND APPARATUS HAVING A CIRCULAR BUFFER FOR THE REPLAY OF RENAL THERAPY MACHINE ALARMS AND EVENTS
A system, methods, and apparatus having a circular buffer for the reply of renal therapy machine alarms and events are disclosed. An example renal therapy apparatus includes a therapy operations processor configured to generate alarms, events, and high fidelity medical device data. The renal therapy apparatus also includes a memory device having a circular buffer configured to store a duration of medical device data. The renal therapy apparatus further includes a control processor configured to receive a stream of medical device data from the therapy operations processor, and write the stream to the circular buffer such that a most recent duration of the stream is stored. The control processor is also configured to detect an occurrence of an alarm or event, and create a reply record that includes an identifier of the alarm or event and the medical device data that is stored in the circular buffer.
A61M 1/16 - Dialysis systemsArtificial kidneysBlood oxygenators with membranes
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
A61M 5/172 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters electrical or electronic
100.
THERMAL DISINFECTION SYSTEM FOR A MEDICAL APPARATUS
A thermal disinfection system and a method to perform a thermal disinfection procedure of fluid lines of a medical apparatus are disclosed herein. In an example, the thermal disinfection procedure comprises at least the steps of receiving a temperature signal from a temperature sensor, determining a measured temperature value of a fluid within a hydraulic circuit, receiving a pressure signal from a pressure sensor, determining a measured local atmospheric pressure value, and driving a heating unit to heat the fluid based on the measured temperature value and the measured local atmospheric pressure value.
