Medical devices for the treatment of infection; medical devices for infection control; electrical device for medical purposes for the reduction of the growth of microbes and biofilms on the surface of an object; medical devices for the reduction and disruption of biofilms; medical devices comprised of LCD display, electrodes, and needle for the reduction of microbes and biofilms; medical devices comprised of LCD display, electrodes, and needle for the reduction of microbes and biofilms on orthopedic, medical and dental implants and devices; medical devices used for orthopedic implants, dental implants, and other medical implants for reduction of the growth of microbes and biofilms; medical devices for orthopedic, medical, and dental implant infection control.
A fluid exchange electrode is defined by a multi-layered electrode body including a conductive electrode material layer disposed in an electrode body and an ionically conducting assembly that interfaces with the skin of a patient. A source of electrolytic fluid is coupled to an inflow tube and configured to permit a volume of electrolytic fluid to be circulated through the electrode body to increase treatment duration and overall electrode life in which the temperature of the cycled electrolytic fluid can be regulated. The cycled electrolytic fluid can be disposed of or preferably recirculated via a return or outflow tube to the source of electrolytic fluid. The herein described fluid exchange electrode can be used as part of a treatment system that applies a DC voltage in order to remove bacteria from a metal surgical implant.
A method and related system for treating a metallic surface in order to eradicate bacteria on the metallic surface using at least three electrodes and in which the metallic surface is one of the electrodes and in which a stimulation voltage is applied to the metallic surface and an accumulated charge is measured. The accumulated charge is compared to a threshold level wherein the stimulation voltage is maintained until the accumulated charge exceeds the threshold level. In at least one version, the metallic surface is that of a surgical implant.
A61B 5/1468 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using chemical or electrochemical methods, e.g. by polarographic means
An apparatus for use with a needle electrode assembly used to disrupt biofilm from an implanted metallic object, such as a replacement orthopedic appliance, includes a body that retains the needle electrode assembly including a projecting needle portion projecting from a lower end of the body. A needle adjustment mechanism enables the length of the projecting needle portion to be adjusted, the needle adjustment mechanism including a spring element within the apparatus body and attached to the needle electrode assembly. The spring element has a substantially nonvariable spring constant such that constant pressure is applied to the needle electrode irrespective of the length of the needle electrode to be brought into contact with the skin of a subject and implanted metallic object, once released by the needle adjustment mechanism. The apparatus includes a plurality of supports that enable the apparatus to be attached to the skin of a subject during treatment wherein a retraction mechanism enables the needle to be withdrawn into the apparatus and a locking mechanism enables safe encapsulation and retention of the needle within the apparatus after treatment.
An apparatus for use with a treatment system to disrupt bacteria from a metallic dental implant includes apparatus configured for mechanical and electrical connection to a device capable of producing an electrical stimulation voltage, and in which a connective body is further configured for attachment to the mouth of a patient and including at least one metal contact. The apparatus can include a mouth guard having at least one integrated or releasably attachable metal contact. Alternatively, at least one clip member can be attached, the clip member having a metal contact portion. The apparatus can be used in conjunction with any electrode of a treatment system in which the electrode is disposed within the mouth of the patient or external.
A wrappable electrode includes a flexible covering and a lead wire connecting the electrode to a stimulating device. The wrappable electrode further includes an adhesive layer to enable attachment to the skin of a patient and an inert conductive layer to which the lead wire is electrically coupled. The electrode is sized to be wrapped about at least a majority of a circumference of a limb of a patient in proximity to a metal surgically implanted device. The adhesive layer includes a buffered hydrogel. The electrode includes a separate conductive layer to evenly distribute electrical current relative to the metal implanted device, with the electrode serving as an anode and the implanted device serving as a cathode in a CVCES treatment system. The electrode can further include at least one feature to ensure proper placement on the skin of the patient.
A61N 1/20 - Applying electric currents by contact electrodes continuous direct currents
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
B32B 5/18 - Layered products characterised by the non-homogeneity or physical structure of a layer characterised by features of a layer containing foamed or specifically porous material
B32B 9/00 - Layered products essentially comprising a particular substance not covered by groups
B32B 9/04 - Layered products essentially comprising a particular substance not covered by groups comprising such substance as the main or only constituent of a layer, next to another layer of a specific substance
B32B 15/20 - Layered products essentially comprising metal comprising aluminium or copper
B32B 15/02 - Layered products essentially comprising metal in a form other than a sheet, e.g. wire, particles
B32B 3/08 - Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by features of form at particular places, e.g. in edge regions characterised by added members at particular parts
B32B 3/26 - Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a particular shape of the outline of the cross-section of a continuous layerLayered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a layer with cavities or internal voids
10.
INTEGRATED ELECTROCHEMICAL TREATMENT SYSTEM FOR REMOVAL OF BIOFILM FROM IMPLANTED DEVICES
A modular system for treatment of a percutaneous implant includes a working electrode, at least one counter electrode and a stimulating device electrically coupled to the at least one counter electrode and the working electrode, the stimulating device being capable of providing a current. The working electrode is the percutaneous implant and in which each of the at least one counter electrode, stimulating device and optionally at least one reference electrode are integrally disposed on an anchoring unit that is releasably securable in relation to the percutaneous implant. Alternatively, the stimulating device can be integrally disposed on the counter electrode, enabling treatment while a prosthetic remains attached to the patient.
Medical devices for the treatment of infection for use on implanted orthopedic implants and other implanted medical implements; medical devices for infection control for use on implanted orthopedic implants and other implanted medical implements; electrical medical device for use on implanted orthopedic implants and other implanted medical implements for the reduction of the growth of microbes and biofilms on the surface of an implanted object for infection treatment; medical devices for the reduction and disruption of biofilms for infection treatment for use on implanted orthopedic implants and other implanted medical implements; medical devices comprised of LCD display, needles, and electrodes for the reduction of microbes and biofilms for infection treatment; medical devices comprised of LCD display, needles, and electrodes for the reduction of microbes and biofilms on orthopedic and medical implants and devices for infection treatment; medical devices comprised of LCD display, needles, and electrodes used on implanted orthopedic implants and other implanted medical implants for reduction and disruption of microbes and biofilms; medical devices for use on implanted orthopedic implants and other implanted medical implements used for orthopedic and medical implant infection control
12.
GALVANOSTATIC METHOD OF MICROBE REMOVAL FROM METAL ORTHOPEDIC DEVICES
A system and related method for eliminating microbes from a metal orthopedic appliance includes a counter electrode and working electrode used for applying treatment, and a reference electrode used for monitoring safety parameters. The working electrode is the implanted appliance. Electrical current is applied between the counter electrode and the working electrode to create electrochemical current through the system and create electrochemical reactions on the surface of the working and counter electrode. The chemical species created at the working electrode provide a mechanism to disrupt and kill microbes on that surface, including bacterial biofilms commonly found on infected orthopedic implants. Circuitry connected to the electrodes keeps the applied current constant and allows the voltage between the working and counter electrode to vary. The reference electrode monitors the voltage at the working electrode in order to provide feedback to a processor as part of a feedback mechanism. The processor is programmed with software logic, preventing the voltage from drifting to ranges that correlate with metal immunity or corrosion regions by limiting or altering the applied current.
A method and apparatus to autonomously analyze the surface area and alloy composition ratios of a metallic implant, such as an orthopedic implant, so that an optimal voltage for biofilm disruption can be selected and make treatment easier based at least in part upon the autonomous detection of a hydrogen evolution reaction threshold.
Medical devices for the treatment of infection; medical
devices for infection control; electrical device for medical
purposes for the reduction of the growth of microbes and
biofilms on the surface of an object; medical devices for
the reduction and disruption of biofilms; medical devices
comprised of LCD display, electrodes, and needle for the
reduction of microbes and biofilms; medical devices
comprised of LCD display, electrodes, and needle for the
reduction of microbes and biofilms on orthopedic and medical
implants and devices; medical devices used for orthopedic
implants and other medical implants for reduction of the
growth of microbes and biofilms; medical devices for
orthopedic and medical implant infection control.
(1) Electrical device for medical purposes for the reduction of the growth of microbes and biofilms on the surface of an object; medical devices comprised of LCD display, electrodes, and needle for the reduction of microbes and biofilms on orthopedic, medical and dental implants and devices; medical devices used for orthopedic implants, dental implants, and other medical implants for reduction of the growth of microbes and biofilms; medical devices for orthopedic, medical, and dental implant infection control.
(1) Electrical device for medical purposes for the reduction of the growth of microbes and biofilms on the surface of an object; medical devices comprised of LCD display, electrodes, and needle for the reduction of microbes and biofilms on orthopedic and medical implants and devices; medical devices used for orthopedic implants and other medical implants for reduction of the growth of microbes and biofilms; medical devices for orthopedic and medical implant infection control.
17.
METHOD FOR OPTIMIZING TREATMENT OF INFECTED METALLIC IMPLANTS BY MEASURING CHARGE TRANSFER
A method and related system for treating a metallic surface in order to eradicate bacteria on the metallic surface using at least three electrodes and in which the metallic surface is one of the electrodes and in which a stimulation voltage is applied to the metallic surface and an accumulated charge is measured. The accumulated charge is compared to a threshold level wherein the stimulation voltage is maintained until the accumulated charge exceeds the threshold level. In at least one version, the metallic surface is that of a surgical implant.
An apparatus for use with a needle electrode assembly used to disrupt biofilm from an implanted metallic object, such as a replacement orthopedic appliance, includes a body that retains the needle electrode assembly including a projecting needle portion projecting from a lower end of the body. A needle adjustment mechanism enables the length of the projecting needle portion to be adjusted, the needle adjustment mechanism including a spring element within the apparatus body and attached to the needle electrode assembly. The spring element has a substantially non- variable spring constant such that constant pressure is applied to the needle electrode irrespective of the length of the needle electrode to be brought into contact with the skin of a subject and implanted metallic object, once released by the needle adjustment mechanism. The apparatus includes a plurality of supports that enable the apparatus to be attached to the skin of a subject during treatment wherein a retraction mechanism enables the needle to be withdrawn into the apparatus and a locking mechanism enables safe encapsulation and retention of the needle within the apparatus after treatment.
A dental implant includes a post and an abutment extending from the post, the post and abutment being made from metal. A crown having a hollow cavity is attached onto the abutment, the crown being configured with a metallic insert that can be accessed and coupled to the abutment to enable electrical contact. In one version, the crown includes a metallic core and in another version, the crown can include a formed recess that receives a portion of the metal abutment. In each version, an exposed metallic area is provided, enabling electrical conduction to the abutment and post as part of a bacterial treatment of the dental implant.
A wrappable electrode configured for use in an electrochemical system for treating a metal surgically implanted device includes a flexible covering, a lead wire configured for connecting the electrode to a stimulating device. The wrappable electrode further includes an adhesive layer to enable the electrode to be attached to the skin of a patient as well as an inert conductive layer to which the lead wire is electrically coupled. The electrode is sized and configured to be wrapped about a majority or more preferably the entire circumference of a limb of a patient in proximity to the metal surgically implanted device. According to a version, the adhesive layer of the wrappable electrode includes a buffered hydrogel as well as anotherconductive layer to evenly distribute electrical current relative to the metal implanted device upon wrapping, with the electrode serving as an anode and the implanted device serving as a cathode in a CVCES treatment system. The electrode can further include at least one feature to ensure proper placement of the electrode on the skin of the patient, as well as that of a reference electrode.
An apparatus for use with a treatment system to disrupt bacteria from a metallic dental implant includes apparatus configured for mechanical and electrical connection to a device capable of producing an electrical stimulation voltage, and in which a connective body is further configured for attachment to the mouth of a patient and including at least one metal contact. The apparatus can include a mouth guard having at least one integrated or releasably attachable metal contact. Alternatively, at least one clip member can be attached, the clip member having a metal contact portion. The apparatus can be used in conjunction with any electrode of a treatment system in which the electrode is disposed within the mouth of the patient or external.
medical devices for the treatment of infection; medical devices for infection control; electrical device for medical purposes for the reduction of the growth of microbes and biofilms on the surface of an object; medical devices for the reduction and disruption of biofilms; medical devices comprised of LCD display, electrodes, and needle for the reduction of microbes and biofilms; medical devices comprised of LCD display, electrodes, and needle for the reduction of microbes and biofilms on orthopedic and medical implants and devices; medical devices used for orthopedic implants and other medical implants for reduction of the growth of microbes and biofilms; medical devices for orthopedic and medical, implant infection control
medical devices for the treatment of infection; medical devices for infection control; electrical device for medical purposes for the reduction of the growth of microbes and biofilms on the surface of an object; medical devices for the reduction and disruption of biofilms; medical devices comprised of LCD display, electrodes, and needle for the reduction of microbes and biofilms; medical devices comprised of LCD display, electrodes, and needle for the reduction of microbes and biofilms on orthopedic and medical implants and devices; medical devices used for orthopedic implants and other medical implants for reduction of the growth of microbes and biofilms; medical devices for orthopedic and medical, implant infection control
24.
GALVANOSTATIC METHOD OF MICROBE REMOVAL FROM METAL ORTHOPEDIC DEVICES
A system and method for eliminating microbes from a metal orthopedic appliance includes a counter electrode and working electrode, an a reference electrode used for monitoring safety parameters. Electrical current is applied between the counter electrode and the working electrode to create electrochemical current through the system and create electrochemical reactions. The chemical species created at the working electrode provide a mechanism to disrupt and kill microbes, including bacterial biofilms commonly found on infected orthopedic implants. Circuitry connected to the electrodes keeps the applied current constant and allows the voltage between the working and counter electrode to vary. The reference electrode monitors the voltage at the working electrode in order to provide feedback to a processor as part of a feedback mechanism. The processor is programmed with software logic, preventing the voltage from drifting to ranges that correlate with metal immunity or corrosion regions by limiting or altering the applied current.
A method and apparatus to autonomously analyze the surface area and alloy composition ratios of a metallic implant, such as an orthopedic implant, so that an optimal voltage for biofilm disruption can be selected and make treatment easier based at least in part upon the autonomous detection of a hydrogen evolution reaction threshold.
A method and apparatus for metal implant contact detection through capacitive measurements is provided. Capacitive measurement is accomplished with a conductive wire/lead, for example a main needle. The measured capacitance increases as the main needle is moved through the skin and tissues, then jumps when the main needle makes contact with the metal implant, thus proving the metal implant exists as well as detecting the location of the metal implant. The jump in capacitive measurement is detectable because the area of capacitance has increased from the main needle alone to the main needle plus the surface area of the metal implant. The apparatus can include a reference needle for taking reference needle capacitive measurements in the tissues surrounding the metal implant to increase the accuracy during use of the apparatus. A housing is provided for supporting the main and reference needles and supporting or housing apparatus electronics.
A device for providing treatment is disclosed. The device provides proper skin electrical conductivity while still being minimally invasive by adhering to the patient's skin that also implements safety measures that off-the-shelf electrode options do not have. This device includes a graphite powder-based skin counter electrode that has a graphite powder suspended in an electrolyte gel that allows for electrochemical conduction between the graphite particles in the graphite powder. The gel is spread over a first side of a hydrogel layer. A device housing is mounted on the hydrogel layer over the first side. The device housing contains the electrolyte gel and graphite powder, defines an opening or lead opening as well as an empty expansion chamber for gaseous anodic byproduct. A metallic wire or rod extends from the electrolyte gel and through the housing opening and connects to a potentiostat. The second side of the hydrogel layer is adhered to the skin of the patient. The graphite powder-based skin counter electrode device takes into account safety.
A dermal electrode device for providing treatment is disclosed. This device includes a graphite powder-based skin counter electrode that has a graphite powder suspended in an electrolyte gel that allows for electrochemical conduction between the graphite particles. The gel is spread over a first side of a hydrogel layer. A device housing contains the electrolyte gel and graphite powder, and defines an opening or lead opening as well as an empty expansion chamber for gaseous anodic byproduct. A metallic wire or rod extends from the electrolyte gel and through the housing opening and connects to a potentiostat. The second side of the hydrogel layer is adhered to the skin of the patient. The graphite powder-based skin counter electrode device implements safety measures.
medical devices for the treatment of infection; medical devices for infection control; electrical device for medical purposes for the reduction of the growth of microbes and biofilms on the surface of an object; medical devices for the reduction and disruption of biofilms; medical devices comprised of LCD display and electrodes for the reduction of microbes and biofilms; medical devices comprised of LCD display and electrodes for the reduction of microbes and biofilms on orthopedic, medical and dental implants and devices; medical devices used for orthopedic implants, dental implants, and other medical implants for reduction of the growth of microbes and biofilms; medical devices for orthopedic, medical, and dental implant infection control
A method and system for bone regeneration is provided that includes an electrical stimulation system for the purpose of accelerating the process of bone healing. The electrical stimulation system includes a coil and a capacitor such that when the coil is powered a pulsed electromagnetic field is generated to accelerate healing. There are also implantable medical devices that include inserts such as an elbow insert. The elbow insert includes or is formed with a repeater coil and a device capacitor, such that when the coil is powered the device coil is powered and delivers a repeater pulsed electromagnetic filed to the surrounding bone. This inductive coupling provides for treatment by both the coil and the repeater coil to accelerate bone healing. The insert may be embodied so it can be used in connection with a plurality of different implantable medical devices.
A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
A61N 2/04 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets using variable fields, e.g. low frequency or pulsating fields
31.
Method and apparatus for metal implant contact detection through capacitive measurements
A method and apparatus for metal implant contact detection through capacitive measurements is provided. Capacitive measurement is accomplished with a conductive wire/lead, for example a main needle. The measured capacitance as the main needle is moved through the skin and tissues increases, then jumps when the main needle makes contact with the metal implant, thus proving the metal implant exists and the location of the metal implant. The jump in capacitive measurement is detectable because the area of capacitance has gone from the main needle to the main needle plus the surface area of the metal implant surface area. The apparatus may also have a reference needle for taking reference needle capacitive measurements in the tissues surrounding the metal implant to increase the accuracy during use of the apparatus. A housing is provided for supporting the main and reference needles and supporting or housing apparatus electronics.
A method and apparatus for metal implant contact detection through capacitive measurements is provided. Capacitive measurement is accomplished with a conductive wire/lead, for example a main needle. The measured capacitance as the main needle is moved through the skin and tissues increases, then jumps when the main needle makes contact with the metal implant, thus proving the metal implant exists and the location of the metal implant. The jump in capacitive measurement is detectable because the area of capacitance has gone from the main needle to the main needle plus the surface area of the metal implant surface area. The apparatus may also have a reference needle for taking reference needle capacitive measurements in the tissues surrounding the metal implant to increase the accuracy during use of the apparatus. A housing is provided for supporting the main and reference needles and supporting or housing apparatus electronics.
Medical and veterinary apparatus and instruments; Diagnostic, examination, and monitoring equipment; Surgical and wound treating equipment; Suture and wound closing materials and products; Electronic medical instruments and devices; Telemetry apparatus for medical use; Remotely controllable electronic bandages/dressings that actively participates in the following activities of wound care, but is not limited to, monitoring, and logging, tracking, and assisting with medical treatment for patients pertaining to wounds, incisions, ulcers, blisters, burns, using electronics means namely, tracking, logging, assisting, in the recording or PH, temperature, pressure, moisture, liquid, size, shape for a round, incision, ulcer, blister, burn.
Medical and veterinary apparatus and instruments; Diagnostic, examination, and monitoring equipment; Surgical and wound treating equipment; Suture and wound closing materials and products; Electronic medical instruments and devices; Telemetry apparatus for medical use; Electric stimulation treatment devices for promoting chronic wound healing, stimulating bone growth, and treating peri-prosthetic joint and other implant infections; Medical devices for enabling a clinician the ability to control treatment parameters and enabling a clinician to receive operating parameters, sense and report biometric data via telemetry.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
(1) Electric stimulation treatment devices, namely, electrical, programmable bandages for promoting chronic wound healing, stimulating bone growth, and treating peri-prosthetic joint and other implant infections; Medical devices for enabling a clinician the ability to control treatment parameters and enabling a clinician to receive operating parameters, sense and report biometric data via telemetry, all in the nature of electrical, programmable bandages
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
15 - Musical instruments
Goods & Services
(1) Remotely controllable electronic bandages and medical dressings that actively participate in the following activities of wound care, namely, monitoring, logging, tracking, and assisting with medical treatment for patients pertaining to wounds, incisions, ulcers, blisters, burns, using electronic means, namely, tracking, logging, and assisting in the recording of pH, temperature, pressure, moisture, liquid, size, shape of a wound, incision, ulcer, blister, burn
A wound healing system and a wound care bandage are provided. The wound care bandage has an electronics housing that houses a battery and wound care microcontroller. A bandage layer is provided and it defines a pad recess in which a pad is disposed. The pad has channels to allow for airflow. The wound care bandage at least first and second snap button electrodes, but there may be more snap button electrodes in other preferred embodiments. There are also electrically conductive adhesive strips with one being in contact with each of the first and second snap button electrodes. When current is controllably supplied to the first and second snap button electrodes a plurality of electric current flow paths are generated and that extend across the wound and stimulate the healing of the wound. The wound care bandage can be monitored and controlled wirelessly.
