An assembly for a positive displacement sampling device, the assembly comprising a tip and an ejector, the tip comprising a body, a mobile capillary retention portion connected to the body by a connector, and a lever secured to the mobile portion, such that moving this portion radially inwards, via the connector, leads to the lever moving radially outwards, the ejector being equipped with a locking member which engages with the lever such that, in the top position of the ejector, the locking member assumes a locking position in which it holds the mobile portion in an active capillary retention position by preventing the lever from moving radially outwards and, during the ejection travel, the locking member permits the lever to move radially outwards.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
CLERMONT AUVERGNE INP (France)
Inventor
Batisse, Nicolas
Abstract
The invention relates to a pipette tip (1, 1') comprising at least one wall portion (2, 2') having a conical shape that is rotationally symmetrical about axis (R), characterized in that said wall portion (2, 2') comprises at least one first wall (20, 20') continuing on a periphery of at least one portion of an inner surface, said first wall projecting from a base (200, 200') in contact with said inner surface to a vertex (201, 201') at an angle of between 40° and 140° with respect to said wall portion (2, 2').
The invention relates to a positive-displacement sampling device (1) comprising an endpiece, an ejector, a fixed body (15) secured to the endpiece, and mobile pipetting equipment (35) comprising a gripper system (34) for gripping the upper end of a piston An operating system (44) is provided, this system operating the clamping collar (40) of the gripper system, the system (44) comprising an elastic return means (46b) positioned between the collar (40) and a mobile main body (36), this system being designed so that during the course of the piston-grasping operation, when the equipment (35) moves axially to bring the body (36) into a predetermined axial position relative to the fixed body, the collar (40) automatically moves from its raised non-clamping position to its lowered clamping position, under the effect of the elastic return means (46b).
A device for a multi-channel pipetting system, comprising a piston holder, a guide rod of the piston holder, which guide rod is mounted slidably in a guide member, a plurality of pistons having a bottom end housed slidably in a suction chamber, and a piston head mounted on the piston holder by way of a mechanical connection. The mechanical connection comprises two contact points which conjointly define a piston-head rotation axis oriented orthogonally with respect to the transverse direction and to the longitudinal central axis of the pipetting system, and the device additionally comprises, associated with the piston, return spring which force the piston head upward against the piston holder, so as to establish the two contact points.
The invention relates to an assembly (30) for a positive displacement sampling device, the assembly comprising a tip (16) and an ejector (20), the tip (16) comprising a body (42), a mobile capillary retention portion (44) connected to the body (42) by a connector, and a lever (54) secured to the mobile portion, such that moving this portion radially inwards, via the connector, leads to the lever (54) moving radially outwards, the ejector (20) being equipped with a locking member (64) which engages with the lever (54) such that, in the top position of the ejector (20), the locking member (64) assumes a locking position in which it holds the mobile portion (44) in an active capillary retention position by preventing the lever (54) from moving radially outwards and, during the ejection travel, the locking member (64) permits the lever (54) to move radially outwards.
A manually-operated mono-channel or multi-channel pipette for the sampling and dispensing of a liquid sample in accordance with a given protocol, comprising a control button equipped with an autonomous control device which can supply a user with information relating to a pipetting operation in real time during the pipetting operation.
09 - Scientific and electric apparatus and instruments
Goods & Services
Chemistry and biology apparatus and instruments, and other
scientific and laboratory apparatus and instruments for
liquid and fluid chromatography; pipette tips; laboratory
and chemistry apparatus and instruments for automatic
taking, transferring, measuring and distributing liquid and
liquid samples and associated consumables; measuring
apparatus and instruments; laboratory consumables, namely,
solid phase extraction cartridges, solid phase extraction
plates, and columns for solid phase extraction and high
performance liquid chromatography.
The invention relates to a device for a multi-channel pipetting system, comprising a piston holder (34), a guide rod (38) of the piston holder, which guide rod (38) is mounted slidably in a guide member (40), a plurality of pistons (20a, 20b) having a bottom end housed slidably in a suction chamber, and a piston head (56) mounted on the piston holder by way of a mechanical connection (62). According to the invention, the mechanical connection (62) comprises two contact points (64a, 64b) which conjointly define a piston-head rotation axis (66) oriented orthogonally with respect to the transverse direction (10) and to the longitudinal central axis (14) of the pipetting system, and the device additionally comprises, associated with the piston (20a, 20b), elastic return means (68) which force the piston head (56) upward against the piston holder (34), so as to establish the two contact points (64a, 64b).
09 - Scientific and electric apparatus and instruments
Goods & Services
(1) Chemistry and biology apparatus and instruments, and other scientific and laboratory apparatus and instruments for liquid and fluid chromatography, namely chromatography apparatus for laboratory use, liquid chromatography apparatus for laboratory use, and apparatus for automatic chromatography; pipette tips; chromatography and liquid chromatography apparatus and instruments for laboratory use for automatic taking, transferring, measuring and distributing liquid and liquid samples and associated consumables, namely multiwell microplates; measuring apparatus and instruments for laboratory use in the field of molecular biology, namely pressure measuring apparatuses, bottle-top machines for dispensing pre-determined volumes of laboratory solutions and solvents, instruments for taking, removing, measuring, and portioning out liquid samples, and disposable pipette tips; laboratory consumables, namely, solid phase extraction cartridges, solid phase extraction plates, and columns for solid phase extraction and high performance liquid chromatography
09 - Scientific and electric apparatus and instruments
Goods & Services
Chemistry and biology apparatus and instruments, and other scientific and laboratory apparatus and instruments for liquid and fluid chromatography, in the nature of chromatography apparatus for laboratory use and liquid chromatography apparatus for laboratory use; laboratory equipment, namely, pipette tips; laboratory and chemistry apparatus and instruments for automatic taking, transferring, measuring and distributing liquid and liquid samples and associated consumables; measuring apparatus and instruments, namely, pressure measuring apparatuses, bottle-top machines for dispensing pre-determined volumes of laboratory solutions and solvents, instruments for taking, removing, measuring, and portioning out liquid samples, and disposable pipette tips for molecular biology applications; laboratory consumables, namely, solid phase extraction cartridges, solid phase extraction plates, and columns for solid phase extraction and high performance liquid chromatography
11.
Device for locking a volume adjustment screw for a pipetting system
A device for locking a volume adjustment screw for a pipetting system, comprising a control member which rotates as one with a position selector, the member cooperating with a locking wheel such that: when the selector is in the free adjustment position, the member ensures that the wheel is axially spaced from another wheel, such that the teeth of the wheels do not cooperate with each other; when the selector is in the fine adjustment position, the member allows the wheel to move away from and then to move axially towards the other wheel while transitioning from one tooth to another; when the selector is in the locking position, the member axially locks the wheel to prevent the teeth from being disengaged.
A dog clutch system for holding the position of a volume adjustment screw for a pipetting system, the system comprising: —a first toothed wheel comprising first teeth; —a second toothed wheel comprising second teeth; —a return spring capable of urging the first and second wheels against each other, the second teeth of the second wheel forming a number N of concentric annular rows, and the second wheel having at least one tooth overlap area in which the N annular rows of second teeth have, respectively, N overlap sectors that overlap each other in a radial direction, and within which the teeth are angularly offset.
G01F 11/02 - Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement
A system for ejecting tips of sampling pipettes, the system comprising: —a button for ejecting a tip which is intended to be moved in translation by an operator's thumb; —a tip ejection device; and —return spring for returning the tip ejection device to a raised position. According to the invention, the system also comprises a lever for controlling the ejection device, the control lever comprising: —a first end which is intended to be fitted onto a part of the pipette; —a second end cooperating with the eject button so as to be acted upon by the latter; and —an intermediate portion for actuating the ejection device.
09 - Scientific and electric apparatus and instruments
Goods & Services
Chemistry and biology apparatus and instruments, and other scientific and laboratory apparatus and instruments for liquid and fluid chromatography; pipette tips; laboratory and chemistry apparatus and instruments for automatic taking, transferring, measuring and distributing liquid and liquid samples and associated consumables; measuring apparatus and instruments; laboratory consumables, namely, solid phase extraction cartridges, solid phase extraction plates, and columns for solid phase extraction and high performance liquid chromatography.
16.
Method for fluorinating a filter for a pipette tip, pipette tip, associated production method and pipette
2 being injected into the enclosure at a partial pressure between 100 Pa and 10000 Pa and step (c) being done at a temperature between 0° C. and 100° C. A pipette tip comprising a filter modified by the fluorination method, a method for producing such a tip, as well as a withdrawing pipette equipped with such a tip.
C08L 23/28 - Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bondCompositions of derivatives of such polymers modified by chemical after-treatment by reaction with halogens or halogen-containing compounds
17.
Pipette system with interchangeable volume counter
This disclosure concerns a pipette system with an interchangeable volume counter. Aspects of the pipette body design and external dimensions allow various functional features of the pipette system, and, thus, various interior adjustment part designs and dimensions, to be accommodated in a single pipette body design. A three-digit volume counter, a four-digit volume counter, or an electronic counter can be installed in the same pipette body design.
The invention relates to a manually-operated mono-channel or multi-channel pipette for the sampling and dispensing of a liquid sample in accordance with a given protocol, comprising a control button equipped with an autonomous control device which can supply a user with information relating to a pipetting operation in real time during the pipetting operation.
The invention relates to a system (2) for ejecting tips of sampling pipettes, the system comprising: - a button (25) for ejecting a tip which is intended to be moved in translation by an operator's thumb (4); - a tip ejection device (24); and - elastic return means (32) for returning the tip ejection device (24) to a raised position. According to the invention, the system also comprises a lever (40) for controlling the ejection device (24), the control lever comprising: - a first end (40a) which is intended to be fitted onto a part (46) of the pipette; - a second end (40b) cooperating with the eject button (25) so as to be acted upon by the latter; and - an intermediate portion (40c) for actuating the ejection device (24).
In order to increase the compatibility of a pipetting system tip with various types of cones, the invention provides a tip comprising a first group of first cone retention elements defining a first maximum outer diameter; a second group of second cone retention elements defining a second maximum outer diameter; a third group of third cone retention elements defining a third maximum outer diameter. The first maximum outer diameter and the second maximum outer diameter being different so as to together define a first tip portion having a first conicity, and the second maximum outer diameter and the third maximum outer diameter being different so as to together define a second tip portion having a second conicity smaller than the first conicity.
The invention concerns a dog clutch system (32) for holding the position of a volume adjustment screw (14) for a pipetting system, the system (32) comprising: - a first toothed wheel (34) comprising first teeth (40); - a second toothed wheel (36) comprising second teeth (46); - elastic return means (38) capable of urging the first and second wheels (34, 36) against each other, the second teeth (46) of the second wheel (36) forming a number N of concentric annular rows (58a, 58b), and the second wheel (36) having at least one tooth overlap area in which the N annular rows (58a, 58b) of second teeth have, respectively, N overlap sectors (66a, 66b) that overlap each other in a radial direction, and within which the teeth (46) are angularly offset.
The invention relates to a device (80) for locking a volume adjustment screw (14) for a pipetting system (1), comprising a control member (88) which rotates as one with a position selector (82), the member (88) cooperating with a locking wheel (34) such that: - when the selector (82) is in the free adjustment position, the member (88) ensures that the wheel (34) is axially spaced from another wheel (36), such that the teeth of the wheels do not cooperate with each other; - when the selector (82) is in the fine adjustment position, the member (88) allows the wheel (34) to move away from and then to move axially towards the other wheel (36) while transitioning from one tooth to another; - when the selector (82) is in the locking position, the member (88) axially locks the wheel (34) to prevent the teeth from being disengaged.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
SIGMA CLERMONT (France)
Inventor
Batisse, Nicolas
Dubois, Marc
Peyroux, Jérémy
Guieu Presle, Béatrice
Abstract
2,22 being injected into the enclosure at a partial pressure between 100Pa and 10000Pa and step (c) being done at a temperature between 0°C and 100°C. The invention also relates to a pipette tip (26) comprising a filter (20) modified by said fluorination method, a method for producing such a tip (26), as well as a withdrawing pipette equipped with such a tip (26).
The invention concerns a support housing for sampling cones for a pipetting system, the housing being intended to be stacked with other identical housings in a stacking direction, and comprising: a support provided with openings for housing the sampling cones; first and second opposing side walls traversed by a virtual median plane. According to the invention, each of the first and second opposing side walls is equipped with a female coupling member and a male coupling member arranged substantially symmetrically to either side of the plane, the two female coupling members of the first and second opposing side walls being arranged to a same side of the plane and the two male coupling members of the first and second opposing side walls being arranged to the other side of the plane.
A pipette for sampling an extended range of volumes of liquid includes a fixed pipette body. An operating rod is movable in translation relative to the pipette body, along a longitudinal axis of the pipette. The pipette includes a suction chamber and a set of N concentric pistons, wherein N corresponds to an integer greater than or equal to 2. Each of the pistons contributes to delimiting the suction chamber. A coupling module couples the operating rod with the set of N concentric pistons. The module is configured in such a way as to be able to be brought into N distinct configurations in which it respectively couples the operating rod with 1, 2, . . . , N pistons.
The invention relates to an accessory (2) for a manually actuated mechanical sampling pipette (1), the accessory being intended to be reversibly mounted around an upper pipette body (4) that forms a grip, the accessory comprising an accessory body (36) and means for attaching the accessory body to the upper pipette body (4). The accessory (2) also comprises: a) a power supply module (82); b) at least one sensor (83, 88, 91, 93) powered by said power supply module (82); and at least one module from among: c) a module (90) for displaying the data acquired by the sensors; d) an alarm module (94) intended to be activated according to the data acquired by the sensors; e) a wireless communication module (96).
In order to improve the ergonomics of a sampling pipette, the invention provides a control member intended to occupy a nominal central position in which a spring brings a locking member into the locking position thereof of the system for adjustment of the volume to be sampled, the member being able to be axially displaced towards each of the two following positions: a low position for ejecting a cone, in which the control member presses on the cone ejector, the movement from the nominal central position to the low position being carried out against the springs; and a high position for unlocking the braking ring, the movement of the control member from the nominal central position to the high position driving a disengagement element to move the locking member against the spring, until release of the braking ring.
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Pipettes; laboratory instruments and accessories. Providing temporary use of non-downloadable software
applications accessible via a website to design, build, and
order customized laboratory instruments and accessories.
31.
MANUALLY-OPERATED MONO-CHANNEL OR MULTI-CHANNEL PIPETTES AND CONTROL BUTTON INTENDED FOR SUCH PIPETTES
The invention relates to a manually-operated mono-channel or multi-channel pipette for the sampling and dispensing of a liquid sample in accordance with a given protocol, comprising a control button equipped with an autonomous control device which can supply a user with information relating to a pipetting operation in real time during the pipetting operation.
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Pipettes. (1) Providing temporary use of non-downloadable software allowing users to design, build, and order customized laboratory instruments via a website.
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Pipettes; laboratory instruments and accessories, namely, pipettes, motorized pipettes and pipette tips Providing temporary use of non-downloadable software applications accessible via a website to design, build, and order customized laboratory instruments and accessories
In order to increase the compatibility of a pipetting system tip with the various types of cones, the invention provides that this tip (6) comprises: -a first group of first cone retention elements (24-1a) defining a larger external diameter (Dmax1); -a second group of second cone retention elements (24-2a) defining a larger external diameter (Dmax2); -a third group of third cone retention elements (24-3a) defining a larger external diameter (Dmax3). The diameter (Dmax1) and the diameter (Dmax2) being different so as to together define a first tip portion (6a) having a first conicity (Con1), and the diameter (Dmax2) and the diameter (Dmax3) being different so as to together define a second tip portion (6b) having a second conicity (Con2) smaller than the first.
The invention concerns a support housing (1) for sampling cones for a pipetting system, the housing being intended to be stacked with other identical housings in a stacking direction (2), and comprising: a support (10) provided with openings (12) for housing the sampling cones; first and second opposing side walls (14a, 14b) traversed by a virtual median plane (P). According to the invention, each of the first and second opposing side walls (14a, 14b) is equipped with a female coupling member (18) and a male coupling member (20) arranged substantially symmetrically to either side of the plane (P), the two female coupling members (18) of the first and second opposing side walls (14a, 14b) being arranged to a same side of the plane (P) and the two male coupling members (20) of the first and second opposing side walls being arranged to the other side of said plane (P).
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
pipettes; laboratory instruments and accessories. Providing a website featuring temporary use of non-downloadable software allowing users to design, build, and order customized laboratory instruments and accessories.
37.
Sampling pipette having an ergonomic control button
An assembly (3) for an ergonomic sampling pipette including a control rod (10) at the end of which is arranged a control button (12) for controlling the movement of the control rod (10) along a longitudinal axis (18) thereof, the button (12) having a pressure surface (11) for receiving the thumb of an operator. The pressure surface (11) of the control button (12) is movable such as to be able, during operation, to assume multiple angles relative to the longitudinal axis (28) of the control rod (10).
In order to extend the operating range of a withdrawing pipette, the invention provides: – a fixed pipette body (22); – an operating rod (12) movable in translation relative to the pipette body (22), along a longitudinal axis (9) of the pipette; – a suction chamber (42); – a set of N concentric pistons (24a-24c), N corresponding to an integer greater than or equal to 2, each of the pistons contributing to delimiting the said suction chamber (42); and – a coupling module (50) coupling the operating rod (12) with the set of N concentric pistons (24a-24c), the said module being configured in such a way as to be able to be brought into N distinct configurations in which it respectively couples the operating rod (12) with 1, 2,…, N pistons.
09 - Scientific and electric apparatus and instruments
Goods & Services
Laboratory apparatus, namely, bottle top dispensers;
scientific and laboratory apparatus and instruments for
liquid and fluid chromatography; scientific and laboratory
apparatus and instruments for the automatic taking,
transferring, measuring and distributing liquid and liquid
samples.
09 - Scientific and electric apparatus and instruments
Goods & Services
(1) Laboratory apparatus, namely, bottle top dispensers; liquid and fluid chromatography apparatus for laboratory use; laboratory apparatus for the automatic taking, transferring, measuring and distributing of liquid and liquid samples, namely, bottle-top machines for dispensing pre-determined volumes of laboratory solutions and solvents
09 - Scientific and electric apparatus and instruments
Goods & Services
Laboratory apparatus, namely, bottle top dispensers in the nature of bottle-top machines for dispensing pre-determined volumes of laboratory solutions and solvents; scientific and laboratory apparatus and instruments for liquid and fluid chromatography, namely, bottle-top machines for dispensing pre-determined volumes of laboratory solutions and solvents; scientific and laboratory apparatus and instruments for the automatic taking, transferring, measuring and distributing liquid and liquid samples, namely, bottle-top machines for dispensing pre-determined volumes of laboratory solutions and solvents
43.
SAMPLING PIPETTE COMPRISING A CONTROL MEMBER WITH DOUBLE FUNCTION FOR EJECTING A CONE AND UNLOCKING THE SYSTEM FOR VOLUME ADJUSTMENT
In order to improve the ergonomics of a sampling pipette, the invention provides a control member (25) intended to occupy a nominal central position in which a spring (60) brings a locking member (46) into the locking position thereof of the system for adjustment of the volume to be sampled, the member (25) being able to be axially displaced towards each of the two following positions: - a low position for ejecting a cone, in which the control member (25) presses on the cone ejector (20), the movement from the nominal central position to the low position being carried out against the springs (32); and - a high position for unlocking the braking ring (40), the movement of the control member (25) from the nominal central position to the high position driving a disengagement element (70) to move the locking member (46) against the spring (60), until release of the braking ring (40).
The invention relates to a control button (12) for a manually actuated sampling pipette, the button comprising lower and upper parts (24a, 24b), one of which is equipped with a force sensor (31) and the other with an actuating member (30). In the vertical position of the button, in a state not subjected to a force, not only does the member (30) ensure that the upper part is retained axially on the lower part (24a), but these parts also define a circular axially retaining connection (42) therebetween, the circular connection exhibiting an axial clearance (47) configured such that, when a pressure is exerted on an off-centre action zone (102a) by the thumb of an operator, the axial clearance (47) is taken up in this zone (102a), while the connection (42) retains a reaction zone (102b), arranged diametrically opposite the action zone (102a), axially and locally relative to the lower part (24a).
09 - Scientific and electric apparatus and instruments
Goods & Services
Laboratory apparatus, namely, bottle top dispensers; Scientific and laboratory apparatus and instruments for liquid and fluid chromatography; Scientific and laboratory apparatus and instruments for the automatic taking, transferring, measuring and distributing liquid and liquid samples.
47.
Positive displacement pipetting system, having a design facilitating the gripping of the piston of the capillary-piston assembly
A pipetting system including a positive displacement sampling pipette as well as a capillary-piston assembly, the piston of which has a top end intended to be held by a gripping device equipping the pipette, the device including a plurality of gripping tongs. The system is designed so that, when the capillary is fitted on the pipette tip and the gripping device is remote from the piston upwards, this device can be displaced downwards with its tongs in an open configuration, up to a determined position in which the tongs, arranged around the top end of the piston, automatically switch into a closed configuration in which they provide a holding of the top end of the piston.
A top part for a sampling pipette including a hollow outer body forming a handle, a pipetting control stem, a device for adjusting and displaying a volume to be sampled, including a first threaded member for adjusting the volume to be sampled crossed by the control stem, the device also comprising a set of first volume graduations angularly spaced from one another around the longitudinal axis and cooperating with a first mark so as to inform about the volume to be sampled. The first threaded member is rotatably integral with one of both elements formed by the set of first volume graduations and the first mark, the mark being axially arranged between the hollow outer body forming a handle and the control knob.
The invention relates to an assembly (3) for an ergonomic sampling pipette including a control rod (10) at the end of which is arranged a control button (12) for controlling the movement of the control rod (10) along a longitudinal axis (18) thereof, the button (12) having a pressure surface (11) for receiving the thumb of an operator. According to the invention, the pressure surface (11) of the control button (12) is movable such as to be able, during operation, to assume multiple angles relative to the longitudinal axis (28) of the control rod (10).
09 - Scientific and electric apparatus and instruments
Goods & Services
(1) Laboratory instruments, namely, liquid handling devices used to magnetically isolate and extract cells, proteins, nucleic acids, and other molecules from biological samples; laboratory consumables for liquid handling devices, namely, microplates and magnetic bead-collection strips
51.
Pipetting system with improved control and volume adjustment
A device for controlling pipetting and adjusting a volume to be sampled, including a pipetting control member; rotary actuating means coupled to the control member; a linking member slidably mounted on the actuating means, the linking member being connected to a piston; volume adjusting means; rotary means defining, for the linking member, a spiral-shaped guiding path, the rotary means being coupled to the adjusting means so that their actuation causes a rotation of the means about a second axis which the guiding path is centered, this rotation leading to a displacement of the linking member along the path, and to a sliding of the member relative to the actuating means.
A bottom part of a positive-displacement pipetting system), including a body slideably housing a device for gripping a piston belonging to a capillary-piston assembly the capillary of which is adapted to be fitted onto an end-fitting of the body. The system also comprises means for ejecting the capillary-piston assembly arranged externally with respect to the body. The system is constructed so that a relative rotation between the ejection means and the gripping device causes it to pass from an open configuration enabling the piston to be released to a closed configuration enabling said piston to be retained, and/or the reverse.
The invention relates to a device (32) for the bottom part of a multichannel pipetting system, comprising two sampling-cone-holding end pieces (6) and also two aspiration chambers (36a, 36b) that engage respectively with the two end pieces, the two aspiration chambers (36a, 36b) being concentric.
09 - Scientific and electric apparatus and instruments
Goods & Services
Laboratory instruments, namely, liquid handling devices used
to magnetically isolate and extract cells, proteins, nucleic
acids, and other molecules from biological samples;
laboratory consumables for liquid handling devices, namely,
microplates and magnetic bead-collection strips.
09 - Scientific and electric apparatus and instruments
Goods & Services
Laboratory instruments, namely, liquid handling devices used to magnetically isolate and extract cells, proteins, nucleic acids, and other molecules from biological samples; laboratory consumables for liquid handling devices, namely, microplates and magnetic bead-collection strips
56.
POSITIVE DISPLACEMENT PIPETTING SYSTEM, HAVING A DESIGN FACILITATING THE GRIPPING OF THE PISTON OF THE CAPILLARY-PISTON ASSEMBLY
The invention relates to a pipetting system (100) comprising a positive displacement sampling pipette (1) and a capillary piston assembly (84), the piston (82) of which comprises a high end to be held by a gripping device (20) provided for the pipette, the device (20) comprising a plurality of gripping clamps (26). According to the invention, the system is designed so that when the capillary (80) is joined on the end-piece (6) of the pipette and the gripping device (20) is remotely removed upwards from the piston (82), this device can be moved downwards with the clamps (26) in an open configuration, to a predetermined position in which the clamps, arranged around the high end of the piston (82), automatically switch into a closed configuration in which they ensure that the high end of the piston (82) is held in place.
The invention relates to an upper part (2) of a sampling pipette (1) comprising: - a hollow outer body (6) forming a handle; - a pipetting control rod (14); - a device (20) for adjusting and displaying a volume to be sampled, comprising a first threaded member (22) for adjusting the volume to be sampled passed through by the control rod (14), the device also comprising a set of first volume graduations (42) spaced angularly apart from one another around the longitudinal axis (3) and cooperating with a first reference (44) so as to provide information on the volume to be sampled. According to the invention, the first threaded member (22) is constrained to rotate with one of the two elements made by the set of first volume graduations (42) and the first reference (44), that element being arranged axially between the hollow outer body (6) forming a handle and the control button (16).
09 - Scientific and electric apparatus and instruments
Goods & Services
(1) Laboratory instruments, namely, liquid handling devices used to magnetically isolate and extract cells, proteins, nucleic acids, and other molecules from biological samples; laboratory consumables for liquid handling devices, namely, microplates and magnetic bead-collection strips.
09 - Scientific and electric apparatus and instruments
Goods & Services
Laboratory instruments, namely, liquid handling devices used to magnetically isolate and extract cells, proteins, nucleic acids, and other molecules from biological samples; laboratory consumables for liquid handling devices, namely, microplates and magnetic bead-collection strips.
60.
Sampling pipette which detects the passage of the piston through a predetermined position
A manually actuated sampling pipette including a piston designed to undergo a dispensing movement during which a first elastic return is loaded, followed by a purge movement during which a second elastic return is loaded, and comprising an electronic device that receives a switching signal notifying passage of the piston through a predetermined position along its dispensing distance or its purge distance, position in which the elastic returns have a predetermined deformation. The pipette also includes a switch that outputs the signal to the electronic device. Furthermore, an elastic support is included which is capable of deforming under the effect of the axial pressure applied by the operator, and the pipette is designed such that deformation of the support, generating switching, is caused when the intensity of the axial pressure is greater than the intensity bringing the elastic returns to their predetermined strain level.
The invention concerns a device (30) for controlling pipetting and adjusting a volume to be collected, comprising: - a pipetting control member (10); - rotary actuating means (32) coupled to the control member; - a link member (42) slidably mounted on the actuating means, the link member being connected to a plunger (50); - volume adjustment means (54); - rotary means (62) defining, for the link member (42), a spiral-shaped guide path (64), the means (62) being coupled to the adjustment means (54) such that the actuation thereof causes the means (62) to rotate about a second axis (66) on which the path (64) is centred, this rotation resulting in the displacement of the link member (42) along the path (34) and the sliding of the member (42) relative to the actuating means (32).
A positive displacement sampling pipette which includes a control rod, the bottom end of which controls the displacement of a device for gripping the top end of a piston of a capillary-piston assembly intended to cooperate with said pipette. The pipette includes an ejection rod of the capillary-piston assembly, movably mounted with respect to the control rod such that its bottom end exerts an ejection strain on the top end of the piston accommodated in the gripping device during a relative displacement between the ejection rod and the control rod.
The invention relates to a bottom part (4) of a positive displacement pipetting system, comprising a body (19) slideably housing a device (20) for taking hold of a piston belonging to a capillary-piston assembly of which the capillary is intended to be push-fitted onto an end fitting of the body. According to the invention it also comprises means (46) of ejecting the capillary-piston assembly, which means are positioned externally with respect to the body (19). Also, it is designed in such a way that a relative rotation of the ejection means (46) and the device (20) for grasping, one with respect to the other, causes said bottom part to pass from an open configuration that allows the piston to be released to a closed configuration that allows this piston to be retained, and/or vice versa.
Method for detecting anomalies during the filling of a liquid metering device with a liquid to be measured out, said metering device comprising at least one suction member and at least one pressure monitoring means arranged for measuring a pressure in relation to said suction member. The detection method comprises steps consisting of: performing a prior pressure calibration of the filling of the device, calculating for a desired volume a tolerance range having an upper limit and a lower limit on the basis of the prior pressure calibration and checking whether the pressure remains within the tolerance range during the filling of the metering device with the liquid to be measured out.
G01F 11/02 - Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement
G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
The invention concerns a manually actuated pipette, comprising a piston intended to perform a dispensing stroke loading first elastic return means, followed by a purge stroke loading second elastic return means, and comprising an electronic device (40) intended to receive a switching signal which translates the passage of the piston through a predetermined position along the dispensing or purge stroke thereof, position wherein the elastic means have a predetermined level of deformation. The pipette also comprises a switch (32) capable of delivering the signal to the electronic device. Moreover, an elastic support (30) is capable of deforming under the effect of the axial pressure of the operator, and the pipette is designed such that the deformation of the support, which results in switching, is caused when the force of the axial pressure is greater than that which places the elastic means at their predetermined level of deformation.
The invention relates to a positive-displacement pipette (1) including a control rod (8), the bottom end (16) of which controls the movement of a device (20) for grasping the top end (86) of a piston (82) belonging to a capillary/piston assembly (84) which is to engage with said pipette. According to the invention, the pipette comprises a rod (46) for ejecting said capillary/piston assembly, which is movably mounted relative to said control rod (8) such that the bottom end (54) thereof is capable of exerting an ejection force on the top end (86) of the piston (82), which is housed in the grasping device (20), upon a relative movement of the ejection rod (46) and the control rod (8).
Process for detecting anomalies during the filling of a liquid metering device with a liquid to be metered, said metering device comprising at least one suction member and at least one pressure control means arranged in order to measure a pressure relating to said suction member. The detection process comprises the steps consisting: in carrying out a prior pressure calibration of the filling of the device, in calculating for a desired volume a tolerance zone having an upper limit and a lower limit from the prior pressure calibration and verifying whether the pressure remains within the tolerance zone during the filling of the metering device with the liquid to be metered.
G01N 35/10 - Devices for transferring samples to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
G01F 11/02 - Apparatus requiring external operation adapted at each repeated and identical operation to measure and separate a predetermined volume of fluid or fluent solid material from a supply or container, without regard to weight, and to deliver it with measuring chambers which expand or contract during measurement
A device for use in a multi- channel pipetting system is provided. The device includes a guidance assembly (302) that includes a piston holder (418), a first and a second rotating element (412, 414), a shaft (416), and a first and a second track (408, 410). The piston holder (418) includes a plurality of aligned notches (426), a first slot (420) extending above the plurality of aligned notches (426) and generally parallel to the plurality of aligned notches (426), and a second and a third slot (422, 424) extending generally orthogonal to the first slot (420). The first rotating element (412) is mounted in the second slot (422) and the second rotating element (414) is mounted in the third slot (424). The shaft (416) is mounted in the first slot (420) and connects the first rotating element (412) to the second rotating element (414). The first rotating element (412) is mounted to roll along the first track (408) and the second rotating element (414) is mounted to roll along the second track (410).
09 - Scientific and electric apparatus and instruments
Goods & Services
Devices for assisting in pipetting for sequential illumination, namely scientific laboratory apparatus; pipetting aids for sequential illumination, namely scientific laboratory apparatus; sequential illumination aids for transparent micro-plaques with multiple wells and transparent microtube blocks for assisting in pipetting, namely scientific laboratory apparatus; electrical base for sequential illumination of wells or tubes for assisting in pipetting, to support transparent micro-plaques with multiple wells or transparent microtube blocks, namely scientific laboratory apparatus; the aforesaid goods may or may not include pipette loaders, wireless communications systems with a pipette for controlling illumination sequences or wireless communications systems with a PC to regulate the desired sequence; pipettes; pipette tips; pipette cones; pipette racks and carousels (laboratory furniture); ejection systems for pipette cones (laboratory furniture); micro-plaques (laboratory furniture); microtubes (laboratory furniture); microtube blocks (laboratory furniture).
A pipetting aid device is provided that includes a support comprising a first face, a plurality of light elements mounted in the support to form a two-dimensional array in the plane of the first face, a first centering structure, and a second centering structure. The first centering structure and the second centering structure are mounted to extend from the first face of the support. The first centering structure includes a first pair and a second pair of stop walls, wherein a pair of stop walls forms a corner. The second centering structure includes a third pair and a fourth pair of stop walls. The first pair and the third pair of stop walls form corners of a first positioning zone of a first type of plate. The second pair and the fourth pair of stop walls form corners of a second positioning zone of a second type of plate. The first centering structure and the second centering structure are positioned outside both the first positioning zone and the second positioning zone.
A pipette is provided. The pipette includes a body, a piston, and a valve. The body includes a nozzle, a first chamber, a second chamber, and a channel formed in the nozzle. The first chamber is isolated from the second chamber, and the channel is isolated from the first chamber and the second chamber. The piston is mounted to slide within the first chamber and the second chamber so that movement of the piston simultaneously increases a first volume of the first chamber and decreases a second volume of the second chamber. The valve is in communication with the first chamber, the second chamber, the channel, and an exterior of the body to selectively provide a communication between the first chamber and the channel, between the second chamber and the channel, between the first chamber and the exterior of the body, and between the second chamber and the exterior of the body.
09 - Scientific and electric apparatus and instruments
Goods & Services
Assistance device for use in sequential illumination, namely
various types of laboratory apparatus; assistance for
sequential illumination pipetting, namely various types of
laboratory apparatus; assistance for sequential illumination
for transparent multiwell microplates and transparent sets
of microtubes for use in pipetting, namely various types of
laboratory apparatus; electrical base unit for sequential
illumination of wells or tubes for use in pipetting,
carrying a transparent multiwell microplate or a transparent
set of microtubes, namely types of laboratory apparatus; the
above-mentioned goods with or without a pipette loader
optionally including a wireless communication system with a
PC for regulating the desired sequence; pipettes; pipette
tips; pipette cones; pipette racks and turnatables
(laboratory furniture); pipette cone ejector systems
(laboratory furniture); microplates (laboratory furniture);
microtubes (laboratory furniture); microtube racks
(laboratory furniture).
A system for determining a viscosity of a fluid is provided. The system includes an intake chamber, a tube, a piston, an actuator, a sensor, and a processor. The tube communicates with the intake chamber and includes a channel including a cylindrical portion with a constant diameter cross section. The piston is mounted in the intake chamber. The actuator is configured to move the piston within the intake chamber at a constant speed during a time window to regulate a fluid in the cylindrical portion. The sensor is configured to measure a pressure a plurality of times during the time window to define a plurality of pressure measurements. The processor is configured to receive the defined plurality of pressure measurements, to determine a slope associated with the received plurality of pressure measurements, and to determine a viscosity of the fluid based on the determined slope.
09 - Scientific and electric apparatus and instruments
Goods & Services
assistance device for use in sequential illumination, namely, a position indicator for use in liquid handling; assistance device for sequential illumination pipetting, namely, a position indicator for use in liquid handling; assistance device for sequential illumination for transparent multiwell microplates and transparent sets of microtubes for use in pipetting, namely, a position indicator for use in liquid handling; electrical base units for a position indicator for use in liquid handling; the above-mentioned goods with or without a pipette loader optionally including a wireless communication system comprising a PC for regulating the desired sequence; laboratory equipment, namely, pipettes, pipette tips, pipette cones, pipette racks and turntables, pipette cone ejector systems comprised primarily of integrated pipette cone ejectors, microplates, microtubes, microtube racks
A device for use in a multi-channel pipetting system is provided. The device includes a body, a plurality of modules mounted to the body, a plurality of pistons mounted to a piston holder for simultaneous movement of the plurality of pistons in a first direction, and a guidance assembly. Each module includes an orifice connecting to an intake chamber. A piston extends into the intake chamber for movement in the first direction. The guidance assembly includes a first rotating element, a second rotating element, a shaft connecting the first rotating element to the second rotating element, and a first track and a second track extending parallel to the first direction. The shaft extends in a second direction orthogonal to the first direction. The first rotating element is mounted to roll along the first track, and the second rotating element is mounted to roll along the second track simultaneously with the plurality of pistons.
The present invention relates to a withdrawal pipette (100) designed so that the movement of a piston (12) along one of its sliding directions (36, 38) simultaneously leads to the increase of the volume in a lower chamber (20) and the reduction of the volume in an upper chamber (22), and vice versa, the pipette additionally comprising fluid communication means (40) that alternately make it possible to establish a first fluid communication (A) between the lower chamber (20) and a channel emerging from a nozzle (28) isolated from this lower chamber, and a second fluid communication (B) between the upper chamber (22) and this same channel (28).
A shaft for a sampling pipette includes a first cylindrical portion, a first annular shoulder, and a second annular shoulder. A first cross section of the first cylindrical portion has a first diameter. The first annular shoulder includes a first transition end adjacent the first cylindrical portion and a second cylindrical portion. A second cross section of the second cylindrical portion has a second diameter. The second annular shoulder includes a second transition end adjacent the first annular shoulder and a third cylindrical portion. A third cross section of the third cylindrical portion has a third diameter. The third diameter is greater than the second diameter which is greater than the first diameter. The second diameter and the third diameter are selected so that a pipette tip contacts the second cylindrical portion and the third cylindrical portion when the pipette tip is mounted on the shaft.
A multivolume pipette is provided. In an exemplary embodiment, the multivolume pipette includes a pipette body, a piston disposed within the pipette body, a first chamber, a second chamber, and a valve. The first chamber and the second chamber are defined at least in part by an inner wall of the pipette body and the piston. The valve is capable of placing the second chamber in fluid communication with an external environment to provide a first volume range of the multivolume pipette. The valve is also capable of placing the second chamber in fluid communication with the first chamber to provide a second volume range of the multivolume pipette.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Pipettes, motorized pipettes, centrifuges, vortex mixers,
peristaltic pumps, laboratory pumps, other laboratory
apparatus and instruments; chemistry apparatus and
instruments; scientific, laboratory apparatus and
instruments. Surgical and medical apparatus and instruments.
09 - Scientific and electric apparatus and instruments
37 - Construction and mining; installation and repair services
Goods & Services
Pipettes, motorized pipettes, centrifuges, vortex mixers,
peristaltic pumps, laboratory pumps, other laboratory
apparatus and instruments, chemistry apparatus and
instruments. Repair of laboratory equipment and apparatus.
A system controls aspiration and dispensation of a liquid in a pipette. The system includes a computing device and the pipette. The computing device includes a pipetting module and a first communication interface. The pipetting module defines an operation to perform at the pipette. The first communication interface sends electronic signals to the pipette, the electronic signals defining the operation to perform at the pipette. The pipette includes a sampling tube, a piston assembly, a piston drive mechanism, a second communication interface, and a microprocessor. The piston assembly mounts to the sampling tube and includes a piston rod that fits within the sampling tube. The piston drive mechanism includes a control rod having a surface that contacts the piston assembly. The piston drive mechanism moves the piston rod of the piston assembly within the sampling tube thereby causing regulation of a liquid in the sampling tube. The second communication interface receives the electronic signals from the computing device. The microprocessor controls the piston drive mechanism and performs the operation defined by the electronic signals.
