Wyss Center for Bio and Neuro Engineering (Switzerland)
Inventor
Bertolote, Tiago
Abstract
The present disclosure can provide an implantable feedthrough device including a feedthrough member formed of insulating material having opposing first and second surfaces. A series of conductors can extend through the feedthrough member between the first and second surfaces. The series of conductors can be arranged in a pattern that has an inner portion vacant of conductors for facilitating access for bonding wires to the conductors on at least one of the first and second surfaces of the feedthrough member.
Wyss Center for Bio and Neuro Engineering (Switzerland)
Inventor
Tompkins, Dana D.
Gongora, Christopher D.
Kitschmann, Achim
Losasso-Tompkins, Jennifer
Clément, Claude
Abstract
Implantable medical devices have a feedthrough from the device to the outside world to pass electrical current from electronics inside the implant to the patient or vice versa. A plurality of sensors and/or signal wires in a wire bundle must connect to the feedthrough and implant in living tissue in the patient. Chemical and physical forces work against the wire connections on the feedthrough. Disclosed embodiments include a biocompatible housing that can be used for an implantable medical device. The biocompatible housing includes a recess with at least one wire exit port, the recess having at least one feedthrough assembly mounted therein. A wire of the feedthrough assembly passes out the wire exit port, and the recess has a top hermetically sealed over it.
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Bertolote, Tiago
Abstract
The present disclosure can provide an implantable feedthrough device including a feedthrough member formed of insulating material having opposing first and second surfaces. A series of conductors can extend through the feedthrough member between the first and second surfaces. The series of conductors can be arranged in a pattern that has an inner portion vacant of conductors for facilitating access for bonding wires to the conductors on at least one of the first and second surfaces of the feedthrough member.
Wyss Center for Bio and Neuro Engineering (Switzerland)
Inventor
Rodriques, Samuel G.
Segar, David J.
Betts-Lacroix, Jonathan
Gandar, Jérôme
Lapinski, Matthew
Abstract
A surgical device for automated drilling includes a drill comprising a drill bit configured to bore through bone and a detector comprising a tissue detection sensor. The drill and detector are independently actuable for insertion and removal of the drill bit and the tissue detection sensor in a bore generated by the drill bit. A surgical system can include the surgical device and a controller configured to actuate the drill to bore through bone, actuate the drill to retract the drill bit from the bore, actuate the detector to insert the tissue detection sensor into the bore, and determine a tissue characteristic at a distal location of the bore based on a sensed signal from the tissue detection sensor.
A61B 17/16 - Instruments for performing osteoclasisDrills or chisels for bonesTrepans
A61B 17/00 - Surgical instruments, devices or methods
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Bertolote, Tiago
Abstract
The present disclosure can provide an implantable feedthrough device including a feedthrough member formed of insulating material having opposing first and second surfaces. A series of conductors can extend through the feedthrough member between the first and second surfaces. The series of conductors can be arranged in a pattern that has an inner portion vacant of conductors for facilitating access for bonding wires to the conductors on at least one of the first and second surfaces of the feedthrough member.
G16H 30/20 - ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
H04N 19/132 - Sampling, masking or truncation of coding units, e.g. adaptive resampling, frame skipping, frame interpolation or high-frequency transform coefficient masking
H04N 19/14 - Coding unit complexity, e.g. amount of activity or edge presence estimation
H04N 19/154 - Measured or subjectively estimated visual quality after decoding, e.g. measurement of distortion
H04N 19/167 - Position within a video image, e.g. region of interest [ROI]
H04N 19/17 - Methods or arrangements for coding, decoding, compressing or decompressing digital video signals using adaptive coding characterised by the coding unit, i.e. the structural portion or semantic portion of the video signal being the object or the subject of the adaptive coding the unit being an image region, e.g. an object
Wyss Center for Bio and Neuro Engineering (Switzerland)
Inventor
Scholler, Jules René Raymond
Jonsson, Joel Axel Christopher
Cheeseman, Bevan Leslie
Sbalzarini, Ivo Fabian
Lamy, Christophe M.
Abstract
An efficient image analysis, processing, and handling based on adaptive particle representation (APR) for processing large scale color image datasets is disclosed. Analyzing large biological mass or tissue samples is achieved at 100+ times faster computation and at improved memory and storage compression ratios. Embodiments are well suited for large 3D cleared tissue samples, large-scale imaging projects such as whole-brain mapping initiatives and human neurohistopathology. A datastore holds adaptive sampling representations of tiles, individual tile positions, and corresponding other image data of a biological mass of interest. An image output using single loading of tiles from the datastore supports a complete image at full resolution of the biological mass.
G06V 10/44 - Local feature extraction by analysis of parts of the pattern, e.g. by detecting edges, contours, loops, corners, strokes or intersectionsConnectivity analysis, e.g. of connected components
Wyss Center for Bio and Neuro Engineering (Switzerland)
Inventor
Baud, Maxime
Kouvas, Georgios
Sobolewski, Aleksander
Abstract
A craniode is positioned in an intra-osseous fashion, namely partly or wholly within the bone of the skull, without penetrating the interior of the skull, while also being positioned below the scalp. A craniode can be used to sense electrical signals from a brain, to electrically stimulate the brain, to emit light signals to the brain, to detect light signals from the brain, to perform functional near infrared spectroscopy on the brain, and to perform photobiomodulation on the brain; and can, for example, provide the ability to perform these procedures in daily life. To resolve the problem of connectivity, each craniode can be connected, or can be equipped with features that make it connectable, to a subcutaneous cable, thus enabling the long-term usage of the craniode in real-life settings; or, active electrodes can be used to transmit signals wirelessly. Transcutaneous and sub-scalp implantation techniques are also provided.
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Scholler, Jules Rene Raymond
Jonsson, Joel Axel Christopher
Cheeseman, Bevan Leslie
Sbalzarini, Ivo Fabian
Lamy, Christophe M.
Abstract
An efficient image analysis, processing, and handling based on adaptive particle representation (APR) for processing large scale color image datasets is disclosed. Analyzing large biological mass or tissue samples is achieved at 100+ times faster computation and at improved memory and storage compression ratios. Embodiments are well suited for large 3D cleared tissue samples, large-scale imaging projects such as whole-brain mapping initiatives and human neurohistopathology. A datastore holds adaptive sampling representations of tiles, individual tile positions, and corresponding other image data of a biological mass of interest. An image output using single loading of tiles from the datastore supports a complete image at full resolution of the biological mass.
G16H 30/20 - ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
H04N 19/14 - Coding unit complexity, e.g. amount of activity or edge presence estimation
H04N 19/154 - Measured or subjectively estimated visual quality after decoding, e.g. measurement of distortion
H04N 19/167 - Position within a video image, e.g. region of interest [ROI]
H04N 19/17 - Methods or arrangements for coding, decoding, compressing or decompressing digital video signals using adaptive coding characterised by the coding unit, i.e. the structural portion or semantic portion of the video signal being the object or the subject of the adaptive coding the unit being an image region, e.g. an object
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Martel, Ulysse
Abstract
A wearable holding device for a neural implant headpiece prevents disconnection or misalignment and is comfortable to wear during sleep or during other regular or long-term use at any time of day. The wearable holding device comprises at least one pad surrounding at least part of the neural implant head-piece, and configured to be mounted to an exterior of a head. The at least one pad forms a cavity configured to receive and cover the at least part of the neural implant head-piece and to continuously maintain stability of the neural implant head-piece relative to the head. A holding textile is configured to hold the at least one pad forming the cavity to the head.
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Martel, Ulysse
Abstract
A wearable holding device for a neural implant headpiece prevents disconnection or misalignment and is comfortable to wear during sleep or during other regular or long-term use at any time of day. The wearable holding device comprises at least one pad surrounding at least part of the neural implant head-piece, and configured to be mounted to an exterior of a head. The at least one pad forms a cavity configured to receive and cover the at least part of the neural implant head-piece and to continuously maintain stability of the neural implant head-piece relative to the head. A holding textile is configured to hold the at least one pad forming the cavity to the head.
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Lapinski, Matthew
Bertolote, Tiago
Abstract
An implant for a neural interface system includes a housing including a base and a flexible portion. The implant further includes at least two anchor attachment structures disposed at the base and arranged at an angle of greater than about 90° and less than about 180° with respect to one another as defined from an approximate center of the base. The anchor attachment structures can be connected by a curved connecting member disposed at a patient-facing surface of the base.
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Bertolote, Tiago
Lapinski, Matthew
Abstract
An implant for a neural interface system includes a housing including a base and a flexible portion. The implant further includes at least two anchor attachment structures disposed at the base and arranged at an angle of greater than about 90° and less than about 180° with respect to one another as defined from an approximate center of the base. The anchor attachment structures can be connected by a curved connecting member disposed at a patient-facing surface of the base.
Wyss Center for Bio and Neuro Engineering (Switzerland)
Inventor
Burdin, Florent
Bertolote, Tiago
Coquoz, Olivier
Abstract
In an example embodiment, an optical communication system includes an implantable optical transmitter and an external optical receiver. The transmitter includes a housing having one or more drivers, plural light emitting sources, and an optical element arranged therein. Each driver converts a digital data signal into modulation signals to drive the sources. Each source generates a light beam in response to a corresponding modulation signal, each light beam contributing to form a single optical signal. The optical element directs the light beams to exit the housing such that a peak position of light intensity of each light beam is separated from a corresponding peak position of light intensity of an adjacent light beam by at least a first distance and less than a second distance. The optical receiver includes at least one photodiode that detects light generated by the sources and generates a reconstructed data signal.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
35 - Advertising and business services
Goods & Services
Pharmaceutical preparations for treating neurological diseases and disorders; Intravenous fluids used for rehydration, nutrition and the delivery of pharmaceutical preparations; Drug delivery agents; Drug delivery agents that facilitate the delivery of pharmaceutical preparations. Medical devices; Medical apparatus and devices for neurological use; Surgical devices and instruments for neurological use; Neurosurgical apparatus; Medical devices for the treatment of neurological conditions; Implantable subcutaneous drug delivery devices; Medical devices, namely, drug delivery devices for infusing medicine into the brain; Medical devices for accessing subcutaneous structures of the human body for the purpose of administering medical treatment. Retail services in relation to pharmaceutical preparations for treating neurological diseases and disorders, intravenous fluids used for rehydration, nutrition and the delivery of pharmaceutical preparations, drug delivery agents, drug delivery agents that facilitate the delivery of pharmaceutical preparations; Retail services in relation to medical devices, medical apparatus and devices for neurological use, surgical devices and instruments for neurological use, neurosurgical apparatus, medical devices for the treatment of neurological conditions, implantable subcutaneous drug delivery devices, medical devices, namely, drug delivery devices for infusing medicine into the brain and medical devices for accessing subcutaneous structures of the human body for the purpose of administering medical treatment; Wholesale services in relation to pharmaceutical preparations for treating neurological diseases and disorders, intravenous fluids used for rehydration, nutrition and the delivery of pharmaceutical preparations, drug delivery agents, drug delivery agents that facilitate the delivery of pharmaceutical preparations; Wholesale services in relation to medical devices, medical apparatus and devices for neurological use, surgical devices and instruments for neurological use, neurosurgical apparatus, medical devices for the treatment of neurological conditions, implantable subcutaneous drug delivery devices, medical devices, namely, drug delivery devices for infusing medicine into the brain and medical devices for accessing subcutaneous structures of the human body for the purpose of administering medical treatment.
Drug delivery catheters; Implantable drug delivery ports; Implantable drug delivery pumps; Medical device for accessing subcutaneous structures of the human body for the purpose of administering medical treatment; Medical devices, namely, minimally invasive neurovascular devices for the treatment of neurological conditions; Transdermal drug delivery patches sold without medication
Neurotechnology devices for medical use, namely, active
implantable neuromonitoring devices for use in establishing
interfaces between the brain and computers and to control
assistive devices, including prostheses and electrical
stimulation systems, and the integration thereof with
communication systems; medical devices consisting of
electrodes, neurotechnology apparatus, portable helmets,
portable processors and software applications for use in
restoring motor skills, communication and other brain
function, as well as for examining neural circuits.
(1) Dispositifs neurotechnologiques à usage médical, à savoir dispositifs de neurosurveillance implantables actifs destinés à établir des interfaces entre le cerveau et l'ordinateur et à commander des dispositifs d'assistance, y compris des prothèses et des systèmes de stimulation électrique, et à les intégrer à des systèmes de communication; dispositifs médicaux consistant en des électrodes, des appareils neurotechnologiques, des casques portables, des processeurs portables et des applications logicielles destinés à rétablir la motricité, la communication et d'autres fonctions cérébrales, ainsi qu'à examiner les circuits neuronaux.
Neurotechnology devices for medical use, namely, active implantable neuromonitoring devices made of artificial material for use in establishing interfaces between the brain and computers and to control assistive devices, including electrical stimulation systems, and the integration thereof with communication systems; medical devices for use in restoring motor skills, communication and other brain function, as well as for examining neural circuits, consisting of electrodes, neurotechnology devices for establishing interfaces between the brain and computers, portable Electroencephalography (EEG) helmets, portable medical processors and downloadable software applications for monitoring brain activity, all sold as a unit;
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Burdin, Florent
Bertolote, Tiago
Coquoz, Olivier
Abstract
In an example embodiment, an optical communication system includes an implantable optical transmitter and an external optical receiver. The transmitter includes a housing having one or more drivers, plural light emitting sources, and an optical element arranged therein. Each driver converts a digital data signal into modulation signals to drive the sources. Each source generates a light beam in response to a corresponding modulation signal, each light beam contributing to form a single optical signal. The optical element directs the light beams to exit the housing such that a peak position of light intensity of each light beam is separated from a corresponding peak position of light intensity of an adjacent light beam by at least a first distance and less than a second distance. The optical receiver includes at least one photodiode that detects light generated by the sources and generates a reconstructed data signal.
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Rodriques, Samuel, G.
Segar, David, J.
Betts-Lacroix, Jonathan
Gandar, Jérôme
Lapinski, Matthew
Abstract
A surgical device for automated drilling includes a drill comprising a drill bit configured to bore through bone and a detector comprising a tissue detection sensor. The drill and detector are independently actuable for insertion and removal of the drill bit and the tissue detection sensor in a bore generated by the drill bit. A surgical system can include the surgical device and a controller configured to actuate the drill to bore through bone, actuate the drill to retract the drill bit from the bore, actuate the detector to insert the tissue detection sensor into the bore, and determine a tissue characteristic at a distal location of the bore based on a sensed signal from the tissue detection sensor.
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Rodriques, Samuel G.
Segar, David J.
Betts-Lacroix, Jonathan
Gandar, Jerome
Lapinski, Matthew
Abstract
A surgical device for automated drilling includes a drill comprising a drill bit configured to bore through bone and a detector comprising a tissue detection sensor. The drill and detector are independently actuable for insertion and removal of the drill bit and the tissue detection sensor in a bore generated by the drill bit. A surgical system can include the surgical device and a controller configured to actuate the drill to bore through bone, actuate the drill to retract the drill bit from the bore, actuate the detector to insert the tissue detection sensor into the bore, and determine a tissue characteristic at a distal location of the bore based on a sensed signal from the tissue detection sensor.
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
Medical apparatus and devices for neurological use, namely, a minimally invasive neurosurgical device to gain access to the brain through controlled movement accessing the neuroanatomical locations, medical imaging apparatus for medical use by professionals; surgical devices and instruments for neurological use; neurosurgical apparatus; medical devices, namely, minimally invasive neurosurgical devices for the treatment of neurological conditions; medical devices, namely, surgical devices that facilitate the identification, separation, or ablation of biologic tissues; medical devices for obtaining body fluid samples Retail store services featuring medical instruments; Retail store services featuring medical apparatus; Wholesale store services featuring medical apparatus; Wholesale store services featuring medical instruments
Medical devices; Medical apparatus and devices for neurological use; Surgical devices and instruments for neurological use; Oxygen sensors for medical use; Precision sensors for medical use; Neurosurgical apparatus; Medical devices, namely, minimally invasive neurovascular devices for the treatment of neurological conditions; Medical devices, namely, surgical devices that facilitate the identification, separation or ablation of biologic tissues; Medical devices for obtaining body fluid samples; Medical devices, namely, pulse generators for neurostimulation; none of the aforementioned being or for use in connection with analyzers, laboratory workstations, or robotic systems for in vitro diagnostics. Retail services in relation to medical instruments; Retail services in relation to medical apparatus; Wholesale services in relation to medical apparatus; Wholesale services in relation to medical instruments.
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Software as a Medical Device (SaMD), recorded, for combining
and processing data from a high channel count of
brain-computer interfaces (BCIs) and interfacing with
monitoring devices and actuators in real time. Platform as a Service (PaaS) featuring computer software
platforms for combining and processing data from a high
channel count of brain-computer interfaces (BCIs) and
interfacing with monitoring devices and actuators in real
time.
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Baud, Maxime
Kouvas, Georgios
Sobolewski, Aleksander
Abstract
A craniode is positioned in an intra-osseous fashion, namely partly or wholly within the bone of the skull, without penetrating the interior of the skull, while also being positioned below the scalp. A craniode can be used to sense electrical signals from a brain, to electrically stimulate the brain, to emit light signals to the brain, to detect light signals from the brain, to perform functional near infrared spectroscopy on the brain, and to perform photobiomodulation on the brain; and can, for example, provide the ability to perform these procedures in daily life. To resolve the problem of connectivity, each craniode can be connected, or can be equipped with features that make it connectable, to a subcutaneous cable, thus enabling the long-term usage of the craniode in real-life settings; or, active electrodes can be used to transmit signals wirelessly. Transcutaneous and sub-scalp implantation techniques are also provided.
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Baud, Maxime
Kouvas, Georgios
Sobolewski, Aleksander
Abstract
A craniode is positioned in an intra-osseous fashion, namely partly or wholly within the bone of the skull, without penetrating the interior of the skull, while also being positioned below the scalp. A craniode can be used to sense electrical signals from a brain, to electrically stimulate the brain, to emit light signals to the brain, to detect light signals from the brain, to perform functional near infrared spectroscopy on the brain, and to perform photobiomodulation on the brain; and can, for example, provide the ability to perform these procedures in daily life. To resolve the problem of connectivity, each craniode can be connected, or can be equipped with features that make it connectable, to a subcutaneous cable, thus enabling the long-term usage of the craniode in real-life settings; or, active electrodes can be used to transmit signals wirelessly. Transcutaneous and sub-scalp implantation techniques are also provided.
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Logiciel en tant que dispositif médical (LtDM), enregistré, pour la combinaison et le traitement de données de signaux neurologiques, de pression artérielle et de température corporelle provenant de canaux d'interfaces pour ordinateurs, nommément d'interfaces cerveau-ordinateur (BCI) sous la forme de casques d'électroencéphalographie (EEG) permettant aux utilisateurs de s'interfacer avec le matériel informatique par l'intermédiaire de l'activité cérébrale, et pour s'interfacer avec des dispositifs de surveillance, nommément des capteurs d'activité à porter sur soi et des actionneurs linéaires électriques en temps réel. (1) Plate-forme informatique en tant que service (PAAS) comprenant des plates-formes logicielles informatiques pour la combinaison et le traitement de données de signaux neurologiques, de pression artérielle et de température corporelle provenant de canaux d'interfaces pour ordinateurs, nommément d'interfaces cerveau-ordinateur (BCI) sous la forme de casques d'électroencéphalographie (EEG) permettant aux utilisateurs de s'interfacer avec le matériel informatique par l'intermédiaire de l'activité cérébrale, et pour s'interfacer avec des dispositifs de surveillance, nommément des capteurs d'activité à porter sur soi et des actionneurs linéaires électriques en temps réel.
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
Software as a Medical Device (SaMD), recorded, for combining and processing data from a high channel count of brain-computer interfaces (BCIs) and interfacing with monitoring devices and actuators in real time Platform as a Service (PaaS) featuring computer software platforms for combining and processing data from a high channel count of brain-computer interfaces (BCIs) and interfacing with monitoring devices and actuators in real time
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Tompkins, Dana D.
Gongora, Christopher D.
Kitschmann, Achim
Losasso-Tompkins, Jennifer
Clément, Claude
Abstract
Implantable medical devices have a feedthrough from the device to the outside world to pass electrical current from electronics inside the implant to the patient or vice versa. A plurality of sensors and/or signal wires in a wire bundle must connect to the feedthrough and implant in living tissue in the patient. Chemical and physical forces work against the wire connections on the feedthrough. Disclosed embodiments include a biocompatible housing that can be used for an implantable medical device. The biocompatible housing includes a recess with at least one wire exit port, the recess having at least one feedthrough assembly mounted therein. A wire of the feedthrough assembly passes out the wire exit port, and the recess has a top hermetically sealed over it.
Wyss Center for Bio and Neuro Engineering (Switzerland)
Inventor
Donoghue, John P.
Kouvas, Georgios
Sobolewski, Aleksander
Zimmermann, Jonas
Vlachos, Ioannis
Baud, Maxime
Flaherty, J. Christopher
Abstract
Provided herein are neural interface systems for a patient, the systems comprising an implantable sensor device and an external processing device. The implantable sensor device comprises: an implantable lead assembly for implantation above the skull and below the skin of the patient, and for recording physiologic parameter information of the patient; and an implantable transmitter for receiving the physiologic parameter information from the implantable lead assembly and for transmitting patient data that is based on the physiologic parameter information. The external processing device receives the patient data from the implantable transmitter. Methods of provided a neural interface are also described.
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Clement, Claude
Bertolote, Tiago
Abstract
An implantable device includes a low-profile housing having a cavity defined in a side thereof, and an element insertably removable with respect to the housing in a direction substantially parallel to a surgical plane of the implantable device. The element has a first portion adapted to be received in the housing cavity. The element further includes a second portion adapted to protrude from the housing upon insertion of the element into the housing cavity. The second portion includes at least one surface adapted for engagement with a surgical instrument for insertion and removal of the element with respect to the housing. A method for servicing the implantable device includes, at an incision proximate an implant location of the implantable device, insertably and removably accessing the element in a direction substantially parallel to a surgical plane of the implantable device.
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Bertolote, Tiago
Gongora, Christopher D.
Tompkins, Dana D.
Clement, Claude
Abstract
An implantable device includes a low-profile housing having a cavity defined in a side thereof, and an element insertably removable with respect to the housing in a direction substantially parallel to a surgical plane of the implantable device. The element has a first portion adapted to be received in the housing cavity. The element further includes a second portion adapted to protrude from the housing upon insertion of the element into the housing cavity. The second portion includes at least one surface adapted for engagement with a surgical instrument for insertion and removal of the element with respect to the housing. A method for servicing the implantable device includes, at an incision proximate an implant location of the implantable device, insertably and removably accessing the element in a direction substantially parallel to a surgical plane of the implantable device.
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Bertolote, Tiago
Gongora, Christopher D.
Tompkins, Dana D.
Clément, Claude
Abstract
An implantable device includes a low-profile housing having a cavity defined in a side thereof, and an element insertably removable with respect to the housing in a direction substantially parallel to a surgical plane of the implantable device. The element has a first portion adapted to be received in the housing cavity. The element further includes a second portion adapted to protrude from the housing upon insertion of the element into the housing cavity. The second portion includes at least one surface adapted for engagement with a surgical instrument for insertion and removal of the element with respect to the housing. A method for servicing the implantable device includes, at an incision proximate an implant location of the implantable device, insertably and removably accessing the element in a direction substantially parallel to a surgical plane of the implantable device.
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Tompkins, Dana D.
Gongora, Christopher D.
Kitschmann, Achim
Losasso-Tompkins, Jennifer
Clement, Claude
Abstract
Implantable medical devices have a feedthrough to the outside world to pass electrical current from electronics inside the implant to the patient or vice versa. A plurality of sensors and/or signal wires must connect to the feedthrough and implant in living tissue. Chemical and physical forces work against the wire connections. The several embodiments include a biocompatible cap or top, shaped to attach onto the rim of the feedthrough device. One or more wire bundle ports are included on the cap. One or two layers of sealant can be injected under the cap. A first layer of epoxy can rigidly protect the wire bonds while an elastomeric silicone can cover the epoxy for a flexible protector. Other embodiments include an implant housing with a recess for the feedthrough; a top can protect the recess. One or more sealants can cover the feedthrough in the recess.
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Tompkins, Dana D.
Gongora, Christopher D.
Kitschmann, Achim
Losasso-Tompkins, Jennifer
Clément, Claude
Abstract
Implantable medical devices have a feedthrough from the device to the outside world to pass electrical current from electronics inside the implant to the patient or vice versa. A plurality of sensors and/or signal wires must connect to the feedthrough and implant in living tissue. Chemical and physical forces work against the wire connections. Embodiments of the present invention include a biocompatible cap or top, shaped to attach onto a rim of the feedthrough device. One or more wire bundle ports are included on the cap. One or two layers of a sealant (e.g., epoxy) can be injected under the cap. A first layer can rigidly protect the wire bonds, and an elastomeric silicone can cover the epoxy for a flexible protector. Other embodiments include an implant housing with a recess for the feedthrough; a top can protect the recess. One or more sealants can cover the feedthrough.
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Tompkins, Dana D.
Gongora, Christopher D.
Kitschmann, Achim
Losasso-Tompkins, Jennifer
Clément, Claude
Abstract
Implantable medical devices have a feedthrough to the outside world to pass electrical current from electronics inside the implant to the patient or vice versa. A plurality of sensors and/or signal wires must connect to the feedthrough and implant in living tissue. Chemical and physical forces work against the wire connections. The several embodiments include a biocompatible cap or top, shaped to attach onto the rim of the feedthrough device. One or more wire bundle ports are included on the cap. One or two layers of sealant can be injected under the cap. A first layer of epoxy can rigidly protect the wire bonds while an elastomeric silicone can cover the epoxy for a flexible protector. Other embodiments include an implant housing with a recess for the feedthrough; a top can protect the recess. One or more sealants can cover the feedthrough in the recess.
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Burdin, Florent
Bertolote, Tiago
Coquoz, Olivier
Abstract
In an example embodiment, an optical communication system includes an implantable optical transmitter and an external optical receiver. The transmitter includes a housing having one or more drivers, plural light emitting sources, and an optical element arranged therein. Each driver converts a digital data signal into modulation signals to drive the sources. Each source generates a light beam in response to a corresponding modulation signal, each light beam contributing to form a single optical signal. The optical element directs the light beams to exit the housing such that a peak position of light intensity of each light beam is separated from a corresponding peak position of light intensity of an adjacent light beam by at least a first distance and less than a second distance. The optical receiver includes at least one photodiode that detects light generated by the sources and generates a reconstructed data signal.
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Burdin, Florent
Bertolote, Tiago
Coquoz, Olivier
Abstract
In an example embodiment, an optical communication system includes an implantable optical transmitter and an external optical receiver. The transmitter includes a housing having one or more drivers, plural light emitting sources, and an optical element arranged therein. Each driver converts a digital data signal into modulation signals to drive the sources. Each source generates a light beam in response to a corresponding modulation signal, each light beam contributing to form a single optical signal. The optical element directs the light beams to exit the housing such that a peak position of light intensity of each light beam is separated from a corresponding peak position of light intensity of an adjacent light beam by at least a first distance and less than a second distance. The optical receiver includes at least one photodiode that detects light generated by the sources and generates a reconstructed data signal.
A61B 5/1455 - Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value using optical sensors, e.g. spectral photometrical oximeters
H04B 13/00 - Transmission systems characterised by the medium used for transmission, not provided for in groups
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
HAUTE ECOLE DU PAYSAGE, D'INGÉNIERIE ET D'ARCHITECTURE DE GENÈVE - HEPIA (Switzerland)
Inventor
Herrera Morales, Jorge Mario
Donoghue, John
Stoppini, Luc
Sobolewski, Aleksander
Woodtli, Alain
Heuschkel, Marc
Abstract
A device for accessing tissue of a subject, and a corresponding method for manufacturing the device, includes a substrate having a top side and a bottom side. One or more projections extend from the bottom side, each projection including an exterior wall portion defining therein an interior shaft portion, the substrate and the multiple projections formed from a monolithic mass. The one or more projections are functionalized to enable transfer, between the subject tissue and the substrate, of at least one of an energy, a signal, a material, and a compound. Functionalization can include laser welding metal microwires or processing a fluid precursor in the interior shaft portion to form a functional electrode material. Embodiments can be manufactured more easily, with greater flexibility, and can provide for more reliable tissue access than existing devices.
41 - Education, entertainment, sporting and cultural services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Educational and training activities related to innovation projects regarding health and life sciences technology; Arranging and conducting of conferences, congresses, scientific conferences and seminars, contests in the field of health and life sciences technology; Sporting and cultural activities; Publication of electronic books and journals on-line; Publication of scientific articles, in particular relating to health and life sciences technology. Scientific and technological services and research and design relating thereto in the field of health and life sciences technology; industrial analysis, industrial research and industrial design services in the fields of health and life sciences technology; quality control and authentication services relating go health and life sciences technology; Design and development of computer software for use with medical technology. Human healthcare services.
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Medical monitoring devices, namely apparatus for invasive
and non-invasive electroencephalographic (EEG) monitoring. Medical monitoring services, namely for invasive and
non-invasive electroencephalographic (EEG) monitoring.
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Dispositifs de surveillance médicale, à savoir appareils pour la surveillance par électroencéphalographie (EEG) invasive et non invasive. (1) Services de surveillance médicale, à savoir pour la surveillance par électroencéphalographie (EEG) invasive et non invasive.
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Medical monitoring devices, namely, apparatus for invasive and non-invasive electroencephalographic (EEG) monitoring Medical monitoring services, namely, for invasive and non-invasive electroencephalographic (EEG) monitoring
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Donoghue, John P.
Kouvas, Georgios
Sobolewski, Aleksander
Zimmermann, Jonas
Vlachos, Ioannis
Baud, Maxime
Flaherty, J. Christopher
Abstract
Provided herein are neural interface systems for a patient, the systems comprising an implantable sensor device and an external processing device. The implantable sensor device comprises: an implantable lead assembly for implantation above the skull and below the skin of the patient, and for recording physiologic parameter information of the patient; and an implantable transmitter for receiving the physiologic parameter information from the implantable lead assembly and for transmitting patient data that is based on the physiologic parameter information. The external processing device receives the patient data from the implantable transmitter. Methods of provided a neural interface are also described.
WYSS CENTER FOR BIO AND NEURO ENGINEERING (Switzerland)
Inventor
Donoghue, John P.
Kouvas, Georgios
Sobolewski, Aleksander
Zimmermann, Jonas
Vlachos, Ioannis
Baud, Maxime
Flaherty, J. Christopher
Abstract
Provided herein are neural interface systems for a patient, the systems comprising an implantable sensor device and an external processing device. The implantable sensor device comprises: an implantable lead assembly for implantation above the skull and below the skin of the patient, and for recording physiologic parameter information of the patient; and an implantable transmitter for receiving the physiologic parameter information from the implantable lead assembly and for transmitting patient data that is based on the physiologic parameter information. The external processing device receives the patient data from the implantable transmitter. Methods of provided a neural interface are also described.
