In some embodiments, the invention provides a system for collecting whole blood. In some embodiments, the system comprises two bags containing solutions which are mixed prior to, at the same time as, or shortly after the addition of donated whole blood to one of the bags. In some embodiments, the blood bags of the system are substantially free of the plasticizer di(2- ethylhexyl) phthalate. In some embodiments, all components of the system are substantially free of the plasticizer di(2-ethylhexyl) phthalate.
A method for collecting plasma includes receiving donor information and demographic information and determining a target volume of plasma to collect based, at least in part, on the received donor information. The method also determines a plasma collection protocol based, at least in part, on the received donor information. The plasma collection protocol has a plurality of collection parameters and a plurality of process parameters. The method may then adjust at least one of the plurality of collection parameters and/or the plurality of process parameters based on the donor information and/or the demographic information. The method also performs a plasma collection procedure according to the determined plasma collection protocol and adjusted collection parameters and/or process parameters. The plasma collection procedure has a plurality of draw cycles and a plurality of return cycles.
A61M 1/38 - Removing constituents from donor blood and returning remainder to body
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
3.
SYSTEM AND METHOD FOR INDIVIDUALIZED PLASMA DONATION
A method for collecting plasma includes receiving donor information and demographic information and determining a target volume of plasma to collect based, at least in part, on the received donor information. The method also determines a plasma collection protocol based, at least in part, on the received donor information. The plasma collection protocol has a plurality of collection parameters and a plurality of process parameters. The method may then adjust at least one of the plurality of collection parameters and/or the plurality of process parameters based on the donor information and/or the demographic information. The method also performs a plasma collection procedure according to the determined plasma collection protocol and adjusted collection parameters and/or process parameters. The plasma collection procedure has a plurality of draw cycles and a plurality of return cycles.
A controller for a blood processing device has a body that may dock and undock with a first blood processing device to connect the controller to the first blood processing device and disconnect the controller from the first blood processing device. A processor within the controller controls the first blood processing device when the controller is docked with the first blood processing device and remotely controls the first blood processing device when undocked. The controller also has a user interface that displays information regarding the first blood processing device and an ongoing apheresis procedure when the controller is docked to the first blood processing device and when the controller is undocked from the first blood processing device.
A plasma testing system includes a plasma collection bottle, having a body and an opening. The blood plasma bottle is configured to contain plasma, and a cartridge connectable to the opening of the bottle. The cartridge is configured to seal the opening of the bottle and includes plasma testing circuitry to test the plasma. The system further has a testing platform including at least one receptacle configured to receive the plasma collection bottle and the cartridge. The at least one receptacle has receiving circuitry in communication with the testing circuitry to receive a test result of the plasma test of the plasma.
A method of managing plasma donation throughput of a plasma donor center includes receiving a request message indicating a request from a donor to donate plasma at the plasma donor center. Plasma donor center data is received from two or more of a plasma donor management system, a plasma center queue management system, or a donor plasma donation mobile application. The wait time is determined within the plasma donor center as a function of plasma center data received from at least two of a plasma donor management system, a plasma center queue management system, or a donor plasma donation mobile application. A reservation message is forwarded to a blood establishment computer system regarding the queue position of the donor, the reservation, or both the donor and the reservation, and a confirmation message is forwarded toward including the determined wait time and preferred arrival time for the donor.
G06Q 10/02 - Reservations, e.g. for tickets, services or events
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
A method and apparatus for managing blood products includes using an image system to capture an image of a container removably holding a plurality of vials containing a blood product, each vial having vial identifying indicia, the image system capturing the vial identifying indicia of each vial, the image system also capturing a visual attribute of the blood product. The captured identifying indicia of each vial is compared to a record having vial information related to the container, and the captured identifying indicia and vial information in the record is used to reconcile the container and plurality of vials to produce a reconciliation. A quality of the blood product as a function of the captured visual attribute is determined, a visual display of the results of the reconciliation and the quality of the blood product is logically produced and forwarded toward a display device.
G06K 19/06 - Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
A portable apheresis system for separating blood into blood components includes a cellular modem configured to transmit and receive information to and from the apheresis device via a cellular connection, and a connector operatively coupled with the cellular modem. The connector is configured to control the cellular modem to transmit and receive apheresis device registration information, establish, using the cellular modem, a cellular communication connection between an apheresis device and a cellular network after detecting the cellular network, transmit registration information relating to the apheresis device to a registration and connectivity computer software server via the wireless communication connection, receive an apheresis registration response from the registration and connectivity computer software server, the apheresis registration response including information relating to the apheresis device registration process, the registration process causing direct or indirect apheresis device communication with a blood establishment computer system remotely positioned relative to the apheresis device.
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
9.
METHOD AND APPARATUS FOR MATCHING ANONYMOUS VITALS DATA TO A BLOOD PRODUCT DONOR RECORD
A blood product donation management method includes determining that a donor is at a location associated with a given vitals device at a given time. A blood establishment computer system receives a vitals message with vitals information relating to the donor obtained from the given vitals device, the vitals message being deidentified to include deidentified information about the donor, and is configured to manage donor information and donation processes. A donor identity of the donor is fetched from the donor records database using the location associated with the identifier of the given vitals device and the given time as database indices to identify the donor with donor identification information. The BECS uses a decision-making framework to determine whether the donor can donate blood and transmits a message indicating whether the donor can donate blood.
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G06F 21/62 - Protecting access to data via a platform, e.g. using keys or access control rules
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
A method for collecting plasma includes determining the weight, height, and hematocrit of a donor, and calculating a donor plasma volume and a target plasma collection volume. The target plasma collection volume is based on the donor plasma volume and a target percentage of plasma. The method then withdraws blood from the donor through a line connected to a blood component separation device, and introduces anticoagulant into the withdrawn blood. The blood component separation device separates the blood into a plasma component and a second blood component, and the plasma component is collected from the blood component separation device and into a plasma collection container. The method may then calculate the volume of pure plasma collected within the plasma collection container, and continue processing/collecting until the calculated volume of pure plasma equals the target plasma collection volume.
Disposable cartridges and methods for detecting and classifying an anticoagulant at a therapeutically relevant amount or higher in a patient. The cartridges include a plurality of chambers, as well as fluidic couplings between chambers. Calcium chloride, Russel Viper Venom (RVV), an ecarin reagent, a Factor Xa reagent, protamine, kaolin, tissue factor, and combinations thereof may be included in a given chamber.
A blood storage container along with an aqueous composition for the storage of packed red blood cells is described. In a preferred embodiment, the container is not made of DEHP plasticizer. In some embodiments, the container is made from a polymeric material and a non-DEHP plasticizer. In some embodiments, the aqueous composition is made of about 1 to about 3 mM adenine, about 20 to about 115 mM dextrose, about 15 to about 60 unmetabolizable membrane-protectant sugar, about 20 to about 30 mM sodium bicarbonate, and about 4 to about 20 mM disodium phosphate. In a most preferred embodiment, the DEHP-lacking container is made from a PVC polymeric material and a DINCH plasticizer and the aqueous composition is made of about 2 mM adenine, about 80 mM dextrose, 55 mM unmetabolizable membrane-protectant sugar, about 26 mM sodium bicarbonate, and about 12 mM disodium phosphate.
A01N 1/126 - Physiologically active agents, e.g. antioxidants or nutrients
A01N 1/146 - Non-refrigerated containers specially adapted for transporting or storing living parts whilst preserving
A61J 1/05 - Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids
A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor
13.
SYSTEM AND METHOD FOR ATTACHING A REMOVABLE ACCESSORY OR WIRELESS TRACKING DEVICE TO A PLASMA STORAGE CONTAINER
A blood product container with removable accessory includes a container body defining the structure of the blood product container and defining an interior. The container body includes a main body portion, a top portion, a neck portion extending from the main body portion to the top portion, and a bottom portion. The container also has a container top configured to seal an opening of the blood product container. An attachment location is located on the container body and receives a removable accessory. The removable accessory is secured to the blood product container when received by the attachment location. The removable accessory may be a tracking device with a switch that activates the tracking device when closed and deactivates the tracking device when open. The switch is normally open when the tracking device is not secured to the container and closed when the tracking device is secured to the container.
A61J 1/05 - Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids
A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor
B65D 25/00 - Details of other kinds or types of rigid or semi-rigid containers
14.
SYSTEM AND METHOD FOR DEPLOYING A HEMOSTATIC IMPLANT IN A TISSUE TRACT
An apparatus is provided for sealing a blood vessel wall penetration disposed at an end of a tissue tract. The apparatus, in one embodiment, includes a shaft having a proximal end and a distal end; an occlusion element near the distal end of the shaft; a hemostatic implant disposed over or adjacent to an exterior surface of the shaft proximal to the occlusion element, said hemostatic implant being hydratable to expand to occlude the tissue tract when exposed to body fluids within the tissue tract; a sleeve peelably disposed over an outer surface of the hemostatic implant and proximal to the occlusion element; and wherein peeling of the sleeve exposes the hemostatic implant such that the hemostatic implant expands and occludes the tissue tract.
An apparatus is provided for sealing a blood vessel wall penetration disposed at an end of a tissue tract. The apparatus, in one embodiment, includes a shaft having a proximal end and a distal end; an occlusion element near the distal end of the shaft; a hemostatic implant disposed over or adjacent to an exterior surface of the shaft proximal to the occlusion element, said hemostatic implant being hydratable to expand to occlude the tissue tract when exposed to body fluids within the tissue tract; a sleeve peelably disposed over an outer surface of the hemostatic implant and proximal to the occlusion element; and wherein peeling of the sleeve exposes the hemostatic implant such that the hemostatic implant expands and occludes the tissue tract.
A method for collecting plasma includes determining the weight and hematocrit of a donor, and inserting a venous-access device into the donor. The method then withdraws blood from the donor through a draw line connected to a blood component separation device, and introduces anticoagulant into the withdrawn blood. The blood component separation device separates the blood into a plasma component and a second blood component, and the plasma component is collected from the blood component separation device and into a plasma collection container. The method may then calculate (1) a percentage of anticoagulant in the collected plasma component, and (2) a volume of pure plasma collected within the plasma collection container. The volume of pure plasma may be based, at least in part, on the calculated percentage of anticoagulant. The method may continue until a target volume of pure plasma is collected within the plasma collection container.
A tortuous path filter for filtering reconstituted plasma, the filter comprising at least two layers of fibers, single-layer filters, or beads, wherein the filter lacks or substantially lacks pores defining a lumen, said lumen having a diameter of larger than (100) microns along a straight path through the filter. The invention provides devices including a tortuous path filter, and methods for producing transfusion-ready plasma comprising: (a) reconstituting dried plasma to produce reconstituted plasma; and (b) passing said reconstituted plasma through the tortuous path filter to produce transfusion-ready plasma.
B01D 29/01 - Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups Filtering elements therefor with flat filtering elements
A method for collecting plasma includes determining the weight, height, and hematocrit of a donor, and calculating a donor plasma volume and a target plasma collection volume. The target plasma collection volume is based on the donor plasma volume and a target percentage of plasma. The method then withdraws blood from the donor through a line connected to a blood component separation device, and introduces anticoagulant into the withdrawn blood. The blood component separation device separates the blood into a plasma component and a second blood component, and the plasma component is collected from the blood component separation device and into a plasma collection container. The method may then calculate the volume of pure plasma collected within the plasma collection container, and continue processing/collecting until the calculated volume of pure plasma equals the target plasma collection volume.
A plasmapheresis centrifuge bowl includes an outer body that is rotatable about a longitudinal axis of the plasmapheresis centrifuge bowl. The outer body has a main body defining an interior, a neck portion extending proximal to the main body, and a shoulder connecting the main body and the neck portion. Within the interior, the bowl has a separation region, and rotation of the bowl separates whole blood within the separation region into a first blood component and a second blood component. The bowl also includes an actuating seal mechanism that transitions between an open state when the plasmapheresis centrifuge bowl is rotating and a closed state when the plasmapheresis centrifuge bowl is not rotating.
B04B 1/12 - Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles with discharging outlets in the plane of the maximum diameter of the bowl with continuous discharge
A61M 1/38 - Removing constituents from donor blood and returning remainder to body
20.
PLASMAPHERESIS CENTRIFUGE BOWL WITH STATIONARY ACTUATING SEAL
A plasmapheresis centrifuge bowl includes an outer body that is rotatable about a longitudinal axis of the plasmapheresis centrifuge bowl. The outer body has a main body defining an interior, a neck portion extending proximal to the main body, and a shoulder connecting the main body and the neck portion. Within the interior, the bowl has a separation region, and rotation of the bowl separates whole blood within the separation region into a first blood component and a second blood component. The bowl also includes an actuating seal mechanism that transitions between an open state when the plasmapheresis centrifuge bowl is rotating and a closed state when the plasmapheresis centrifuge bowl is not rotating.
A61M 1/38 - Removing constituents from donor blood and returning remainder to body
B04B 1/12 - Centrifuges with rotary bowls provided with solid jackets for separating predominantly liquid mixtures with or without solid particles with discharging outlets in the plane of the maximum diameter of the bowl with continuous discharge
A method for collecting plasma includes determining the weight and hematocrit of a donor, and inserting a venous-access device into the donor. The method then withdraws blood from the donor through a draw line connected to a blood component separation device, and introduces anticoagulant into the withdrawn blood. The blood component separation device separates the blood into a plasma component and a second blood component, and the plasma component is collected from the blood component separation device and into a plasma collection container. The method may then calculate (1) a percentage of anticoagulant in the collected plasma component, and (2) a volume of pure plasma collected within the plasma collection container. The volume of pure plasma may be based, at least in part, on the calculated percentage of anticoagulant. The method may continue until a target volume of pure plasma is collected within the plasma collection container.
(1) Medical apparatus in the nature of a dispenser, for cooling and dispensing blood, namely, a temperature-controlled dispenser for storing and dispensing blood
(2) Refrigerators for the preservation and storage of bodily fluids, organs, tissues
Medical apparatus for cooling blood, dispensing blood Refrigerators for medical storage purposes for the preservation of bodily fluids, organs, and tissues
25.
Health care provider data systems processing and analytics
A method for generating a directive for maintaining an objective includes integrating a control center system with a plurality of healthcare provider data systems and obtaining information from the healthcare provider data system(s). The method may then use artificial intelligence to correlate the obtained information against an identified business objective of a donation center and generate, using a heuristic model, a directive to the donation center(s) to achieve the identified business objective. The method may then present the directive a user and/or user system such that the directive may carried out.
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
G06Q 10/0639 - Performance analysis of employeesPerformance analysis of enterprise or organisation operations
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
G06Q 50/22 - Social work or social welfare, e.g. community support activities or counselling services
A method of testing blood hemostasis may include introducing a blood sample into a fluid processing structure, where the fluid processing structure contains a reagent, for example in a passage. The fluid sample may be processed by passing a portion through the fluid processing structure so as to contact the reagent. The processed portion is then communicated to a sample retention structure of the fluid processing structure. Testing is accomplished by vibratory excitation of the processed portion to obtain data indicative of at least one hemostasis parameter.
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
G01N 11/16 - Investigating flow properties of materials, e.g. viscosity or plasticityAnalysing materials by determining flow properties by moving a body within the material by measuring damping effect upon oscillatory body
G01N 29/032 - Analysing fluids by measuring attenuation of acoustic waves
G01N 29/036 - Analysing fluids by measuring frequency or resonance of acoustic waves
In various aspects, the invention provides dry (or solid) compositions or formulations (in the form of powder, capsules, and tablets) to be mixed with donated whole blood. In another aspect, the invention provides dry or solid compositions or formulations (in the form of powder, capsules, and tablets) to be mixed with a donated blood product such as red blood cells. In further aspects, the invention provides a blood bag comprising an interior containing dry (or solid) compositions or formulations (in the form of powder, capsules, and tablets) to be mixed with donated whole blood or a blood product thereof. In further aspects, the invention provides whole blood, or a blood product thereof, mixed with a dry formulation as described herein.
A method for collecting plasma includes determining the weight, height, and hematocrit of a donor, and calculating a donor plasma volume and a target plasma collection volume. The target plasma collection volume is based on the donor plasma volume and a target percentage of plasma. The method then withdraws blood from the donor through a line connected to a blood component separation device, and introduces anticoagulant into the withdrawn blood. The blood component separation device separates the blood into a plasma component and a second blood component, and the plasma component is collected from the blood component separation device and into a plasma collection container. The method may then calculate the volume of pure plasma collected within the plasma collection container, and continue processing/collecting until the calculated volume of pure plasma equals the target plasma collection volume.
A blood component cooling container includes a body portion having a proximal end and a distal end. The body portion defines an interior volume, and includes a plurality of cooling vanes that extend radially outward from the body portion. The cooling vanes increase the external surface area of the blood component cooling container. The blood component cooling container also has an opening within the body portion and configured to receive collected plasma.
A61J 1/05 - Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids
A61M 1/34 - Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration, diafiltration
31.
DISPOSABLE CARTRIDGE FOR CLASSIFICATION OF ANTICOAGULANT AND METHOD OF USE
Disposable cartridges and methods for detecting and classifying an anticoagulant at a therapeutically relevant amount or higher in a patient. The cartridges include a plurality of chambers, as well as fluidic couplings between chambers. Calcium chloride, Russel Viper Venom (RVV), an ecarin reagent, a Factor Xa reagent, protamine, kaolin, tissue factor, and combinations thereof may be included in a given chamber.
A whole blood storage system that includes whole blood leukoreduction with pH optimization for improved RBC storage. Such a system can provide leukoreduced whole blood for field medical use, but would preserve the RBCs and most plasma coagulation activity for at least about 2 weeks, or about 3 weeks, or about 4 weeks, or about 5 weeks or about 6 weeks so that the units would not go to waste.
A tortuous path filter for filtering reconstituted plasma, the filter comprising at least two layers of fibers, single-layer filters, or beads, wherein the filter lacks or substantially lacks pores defining a lumen, said lumen having a diameter of larger than (100) microns along a straight path through the filter. The invention provides devices including a tortuous path filter, and methods for producing transfusion-ready plasma comprising: (a) reconstituting dried plasma to produce reconstituted plasma; and (b) passing said reconstituted plasma through the tortuous path filter to produce transfusion-ready plasma.
09 - Scientific and electric apparatus and instruments
Goods & Services
Downloadable computer application software for mobile phones
and computers, namely, downloadable software for use by
potential blood or plasma donors to see donation history,
find donation drives and schedule appointments, receive
education about the donation process, complete health
history questionnaires, receive notification of use of
donated blood or plasma; downloadable computer application
software for mobile phones and computers, namely,
downloadable software for use by blood or plasma donation
center operators for donation trend analysis, to target and
identify donors and prospective donors for marketing message
outreach via social media, e-mail, or SMS, conduct donor
surveys, and for providing information about the donor to
donation center workers to enhance the donor's in-center
experience; computer application software for mobile phones
and computers, namely, recorded software for use by
potential blood or plasma donors to see donation history,
find donation drives and schedule appointments, receive
education about the donation process, complete health
history questionnaires, receive notification of use of
donated blood or plasma; computer application software for
mobile phones and computers, namely, recorded software for
use by blood or plasma donation center operators for
donation trend analysis, to target and identify donors and
prospective donors for marketing message outreach via social
media, e-mail, or SMS, conduct donor surveys, and for
providing information about the donor to donation center
workers to enhance the donor's in-center experience.
09 - Scientific and electric apparatus and instruments
Goods & Services
Downloadable computer software for mobile phones and
computers, namely, software for use by blood or blood plasma
donation centers to collect and display information
regarding blood plasma donor flow and activity within the
center; downloadable computer software for mobile phones and
computers, namely, software for use by blood or plasma
donation center operators for center employee performance
analysis.
37.
Bracket, thrombelastography device, and support system
A bracket a thrombelastography device, and a support system are disclosed. The bracket comprises: a fixed support part (101), a movable support part (102), and a connection part (103). The connection part comprises a first fixing connection member (1031) and a second fixing connection member (1032). The first fixing connection member is fixedly connected to the fixed support part; the second fixing connection member is fixedly connected to the movable support part; the first fixing connection member is connected to the second fixing connection member in point contact fashion, such that the first fixing connection member and the second fixing connection member can rotate relative to each other; the movable support part is fixedly connected to a supported object; when driven by the supported object, the movable support part rotates relative to the fixed support part by means of the point contact between the first fixing connection member and the second fixing connection member. The thrombelastography device comprises a rotational shaft and a bracket. The rotational resistance to the supported object when it rotates can be reduced.
G01N 33/49 - Physical analysis of biological material of liquid biological material blood
G01N 11/06 - Investigating flow properties of materials, e.g. viscosity or plasticityAnalysing materials by determining flow properties by measuring flow of the material through a restricted passage, e.g. tube, aperture by timing the outflow of a known quantity
G01N 11/14 - Investigating flow properties of materials, e.g. viscosity or plasticityAnalysing materials by determining flow properties by moving a body within the material by using rotary bodies, e.g. vane
G01N 11/16 - Investigating flow properties of materials, e.g. viscosity or plasticityAnalysing materials by determining flow properties by moving a body within the material by measuring damping effect upon oscillatory body
G01N 33/86 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving blood coagulating time
09 - Scientific and electric apparatus and instruments
Goods & Services
(1) Downloadable computer software for mobile phones and computers, namely, software for use by blood or blood plasma donation centers to collect and display information regarding blood plasma donor flow and activity within the center; downloadable computer software for mobile phones and computers, namely, software for use by blood or plasma donation center operators for center employee performance analysis
09 - Scientific and electric apparatus and instruments
Goods & Services
(1) Downloadable computer software for mobile phones and computers, namely, software for use by blood or blood plasma donation centers to collect and display information regarding blood plasma donor flow and activity within the center; downloadable computer software for mobile phones and computers, namely, software for use by blood or plasma donation center operators for center employee performance analysis
09 - Scientific and electric apparatus and instruments
Goods & Services
Downloadable computer software for mobile phones and computers, namely, software for use by blood or blood plasma donation centers to collect and display information regarding blood plasma donor flow and activity within the center; downloadable computer software for mobile phones and computers, namely, software for use by blood or plasma donation center operators for center employee performance analysis.
09 - Scientific and electric apparatus and instruments
Goods & Services
(1) Downloadable computer application software for mobile phones and computers, namely, downloadable software for use by potential blood or plasma donors to see donation history, find donation drives and schedule appointments, receive education about the donation process, complete health history questionnaires, receive notification of use of donated blood or plasma; downloadable computer application software for mobile phones and computers, namely, downloadable software for use by blood or plasma donation center operators for donation trend analysis, to target and identify donors and prospective donors for marketing message outreach via social media, e-mail, or SMS, conduct donor surveys, and for providing information about the donor to donation center workers to enhance the donor's in-center experience; computer application software for mobile phones and computers, namely, recorded software for use by potential blood or plasma donors to see donation history, find donation drives and schedule appointments, receive education about the donation process, complete health history questionnaires, receive notification of use of donated blood or plasma; computer application software for mobile phones and computers, namely, recorded software for use by blood or plasma donation center operators for donation trend analysis, to target and identify donors and prospective donors for marketing message outreach via social media, e-mail, or SMS, conduct donor surveys, and for providing information about the donor to donation center workers to enhance the donor's in-center experience
09 - Scientific and electric apparatus and instruments
Goods & Services
Downloadable computer application software for mobile phones and computers, namely, downloadable software for use by potential blood or plasma donors to see donation history, find donation drives and schedule appointments, receive education about the donation process, complete health history questionnaires, receive notification of use of donated blood or plasma; downloadable computer application software for mobile phones and computers, namely, downloadable software for use by blood or plasma donation center operators for donation trend analysis, to target and identify donors and prospective donors for marketing message outreach via social media, e-mail, or SMS, conduct donor surveys, and for providing information about the donor to donation center workers to enhance the donor's in-center experience; computer application software for mobile phones and computers, namely, recorded software for use by potential blood or plasma donors to see donation history, find donation drives and schedule appointments, receive education about the donation process, complete health history questionnaires, receive notification of use of donated blood or plasma; computer application software for mobile phones and computers, namely, recorded software for use by blood or plasma donation center operators for donation trend analysis, to target and identify donors and prospective donors for marketing message outreach via social media, e-mail, or SMS, conduct donor surveys, and for providing information about the donor to donation center workers to enhance the donor's in-center experience.
44.
Blood storage container containing aqueous composition for the storage of red blood cells
A blood storage container along with an aqueous composition for the storage of packed red blood cells is described. In a preferred embodiment, the container is not made of DEHP plasticizer. In some embodiments, the container is made from a polymeric material and a non-DEHP plasticizer. In some embodiments, the aqueous composition is made of about 1 to about 3 mM adenine, about 20 to about 115 mM dextrose, about 15 to about 60 unmetabolizable membrane-protectant sugar, about 20 to about 30 mM sodium bicarbonate, and about 4 to about 20 mM disodium phosphate. In a most preferred embodiment, the DEHP-lacking container is made from a PVC polymeric material and a DINCH plasticizer and the aqueous composition is made of about 2 mM adenine, about 80 mM dextrose, 55 mM unmetabolizable membrane-protectant sugar, about 26 mM sodium bicarbonate, and about 12 mM disodium phosphate.
A61J 1/05 - Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids
A61J 1/14 - Containers specially adapted for medical or pharmaceutical purposes DetailsAccessories therefor
A continuous flow centrifuge bowl includes a rotatable outer body, and a top and bottom core that are rotatable with the outer body. The bottom core has a wall extending proximally from a bottom wall. The proximally extending wall is radially outward from at least a portion of the top core and, together with the top core, defines a primary separation region in which initial separation of the whole blood occurs. The bowl may also have a secondary separation region located between the top core and the outer body, and a rotary seal that couples an inlet port and two outlet ports to the outer body. The inlet port may be connected to an inlet tube that extends distally into a whole blood introduction region. Additionally, one of the outlet ports may be connected to an extraction tube that extends into a region below the bottom core.
01 - Chemical and biological materials for industrial, scientific and agricultural use
10 - Medical apparatus and instruments
Goods & Services
Chemical preparations for scientific purposes, namely, chemical solutions used to aid in the anticoagulation, preservation, or storage of whole blood and cellular and non-cellular blood products, in particular plasma, platelets, and red blood cells for scientific and laboratory purposes; chemical preparations for the manufacture of tubing, bags, and filters for collecting or storing whole blood and cellular and non-cellular blood products, in particular plasma, platelets, white blood cells, plasma proteins in the nature of immunoglobulins, and red blood cells Medical devices, namely, kits for the collection, preservation, or storage of whole blood and cellular and non-cellular blood products, in particular plasma, platelets, white blood cells, and red blood cells, comprised of medical tubing for transfusions, empty blood storage bags, and medical whole blood and cellular and non-cellular blood products, in particular plasma, platelets, plasma proteins in the nature of immunoglobulins, and red blood cells, as well as anticoagulation and chemical storage solutions; filters for blood and blood components for medical use, namely, filters for reducing leukocytes and white blood cells in collected whole blood, and cellular and non-cellular blood products, in particular plasma, platelets, and red blood cells
09 - Scientific and electric apparatus and instruments
Goods & Services
Downloadable computer software for mobile phones and computers, namely, software for use by blood and blood plasma donation centers to collect and display information regarding movement of blood plasma donors and activity within the center; downloadable computer software for mobile phones and computers, namely, software for use by blood and blood plasma donation center operators for center employee performance analysis
01 - Chemical and biological materials for industrial, scientific and agricultural use
Goods & Services
Chemical preparations for scientific purposes, namely, chemical solutions used to aid in the storage or preservation of red blood cells for scientific and laboratory purposes
Medical devices, namely, kits for the collection, anticoagulation or storage of whole blood, comprised of medical tubing for transfusions, empty blood storage bags, and anticoagulation chemical solutions and chemical storage solutions for storing whole blood for medical purposes
51.
Bracket, thrombelastography device, and support system
A bracket, a thrombelastography device, and a support system are disclosed. The bracket comprises: a fixed support part (101), a movable support part (102), and a connection part (103). The connection part comprises a first fixing connection member (1031) and a second fixing connection member (1032). The first fixing connection member is fixedly connected to the fixed support part; the second fixing connection member is fixedly connected to the movable support part; the first fixing connection member is connected to the second fixing connection member in point contact fashion, such that the first fixing connection member and the second fixing connection member can rotate relative to each other; the movable support part is fixedly connected to a supported object; when driven by the supported object, the movable support part rotates relative to the fixed support part by means of the point contact between the first fixing connection member and the second fixing connection member. The thrombelastography device comprises a rotational shaft and a bracket. The rotational resistance to the supported object when it rotates can be reduced.
G01N 33/49 - Physical analysis of biological material of liquid biological material blood
G01N 11/14 - Investigating flow properties of materials, e.g. viscosity or plasticityAnalysing materials by determining flow properties by moving a body within the material by using rotary bodies, e.g. vane
G01N 33/86 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving blood coagulating time
G01N 11/06 - Investigating flow properties of materials, e.g. viscosity or plasticityAnalysing materials by determining flow properties by measuring flow of the material through a restricted passage, e.g. tube, aperture by timing the outflow of a known quantity
G01N 11/16 - Investigating flow properties of materials, e.g. viscosity or plasticityAnalysing materials by determining flow properties by moving a body within the material by measuring damping effect upon oscillatory body
A method for collecting plasma includes determining the weight and hematocrit of a donor, and inserting a venous-access device into the donor. The method then withdraws blood from the donor through a draw line connected to a blood component separation device, and introduces anticoagulant into the withdrawn blood. The blood component separation device separates the blood into a plasma component and a second blood component, and the plasma component is collected from the blood component separation device and into a plasma collection container. The method may then calculate (1) a percentage of anticoagulant in the collected plasma component, and (2) a volume of pure plasma collected within the plasma collection container. The volume of pure plasma may be based, at least in part, on the calculated percentage of anticoagulant. The method may continue until a target volume of pure plasma is collected within the plasma collection container.
A sample testing cartridge is usable to perform a variety of tests on a visco-elastic sample, such hemostasis testing on a whole blood or blood component sample. The cartridge includes a sample processing portion that is in fluid communication with a sample retention structure. A suspension, such as a beam, arm, cantilever or similar structure supports or suspends the sample retention portion relative to the sample processing portion in a unitary structure. In this manner, the sample retention portion may be placed into dynamic excitation responsive to excitation of the cartridge and correspondingly dynamic, resonant excitation of the sample contained within the sample retention portion, while the sample processing portion remains fixed. Observation of the excited sample yields data indicative of hemostasis. The data may correspond to hemostasis parameters such as time to initial clot formation, rate of clot formation, maximum clot strength and degree of clot lysis.
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
G01N 11/16 - Investigating flow properties of materials, e.g. viscosity or plasticityAnalysing materials by determining flow properties by moving a body within the material by measuring damping effect upon oscillatory body
G01N 29/032 - Analysing fluids by measuring attenuation of acoustic waves
G01N 29/036 - Analysing fluids by measuring frequency or resonance of acoustic waves
A whole blood storage system that includes whole blood leukoreduction with pH optimization for improved RBC storage. Such a system can provide leukoreduced whole blood for field medical use, but would preserve the RBCs and most plasma coagulation activity for at least about 2 weeks, or about 3 weeks, or about 4 weeks, or about 5 weeks or about 6 weeks so that the units would not go to waste.
A whole blood storage system that includes whole blood leukoreduction with pH optimization for improved RBC storage. Such a system can provide leukoreduced whole blood for field medical use, but would preserve the RBCs and most plasma coagulation activity for at least about 2 weeks, or about 3 weeks, or about 4 weeks, or about 5 weeks or about 6 weeks so that the units would not go to waste.
Quality control formulations that do not require human donor-derived blood components for use in testing the efficacy of viscoelastic analysis reagents, and methods for preparing these formulations, are described.
G01N 24/08 - Investigating or analysing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using nuclear magnetic resonance
57.
Hemostasis measurement device quality control formulations
Quality control formulations that do not require human donor-derived blood components for use in testing the efficacy of viscoelastic analysis reagents, and methods for preparing these formulations, are described.
G01N 31/00 - Investigating or analysing non-biological materials by the use of the chemical methods specified in the subgroupsApparatus specially adapted for such methods
G01N 33/96 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving blood or serum control standard
58.
Thrombelastography device, heating apparatus, blood coagulation analysis system and rotational angle measurement method
A thrombelastography device, a heating apparatus, a blood coagulation analysis system, and a rotational angle measurement method are disclosed. The thrombelastography device consists of a plurality of thrombelastography device splits (2) that are horizontally arranged in parallel. The thrombelastography device split (2) comprises a worktable (4), a rack (5), a test bar (6), a tester (8), and a processor (9). The thrombelastography device overcomes the defect in the prior art that the measurement result of a thrombelastography device is inaccurate. The amount of reflected light is used as a reference for thrombelastographic evaluation, and thus the result is more accurate.
G01N 33/49 - Physical analysis of biological material of liquid biological material blood
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
B01L 7/00 - Heating or cooling apparatusHeat insulating devices
B01L 9/02 - Laboratory benches or tablesFittings therefor
G01N 11/00 - Investigating flow properties of materials, e.g. viscosity or plasticityAnalysing materials by determining flow properties
G01N 11/14 - Investigating flow properties of materials, e.g. viscosity or plasticityAnalysing materials by determining flow properties by moving a body within the material by using rotary bodies, e.g. vane
59.
Methods and devices for the enrichment of immunoglobulin from blood
A method for extracting at least 55% of immunoglobulin such as IgG from a biological fluid. The biological fluid containing immunoglobulin is contacted with a solid support covalently bonded to a ligand that specifically binds to immunoglobulin under conditions sufficient for non-covalent binding of immunoglobulin to the ligand. The solid support is contacted with an elution solution under conditions whereby the non-covalently bound immunoglobulin is released from the ligand and into the elution solution, wherein at least 55% of the IgG present in the biological fluid is extracted into the elution solution. The method, in some embodiments, provides a method for enriching immunoglobulin from a biological fluid comprising obtaining an initial biological fluid suspected of containing immunoglobulin and removing non-immunoglobulin components naturally occurring in the initial biological fluid to obtain a non-immunoglobulin component-reduced biological fluid.
An apparatus for measuring pressure within a fluid path includes a housing defining the structure of the apparatus. The housing includes a fluid path that extends through the housing and allows a fluid to pass through the housing. The apparatus also includes a first volume chamber that is in fluid communication with the fluid path and has a first volume chamber opening, and a second volume chamber with a second volume chamber opening that is less than the first volume chamber opening. A diaphragm separates the first volume chamber from the second volume chamber and fluidly disconnects the second volume chamber from the fluid path. The diaphragm deforms based upon the pressure within the fluid path. The apparatus also includes an interface that is connectable to a pressure sensor, and the second volume chamber is in fluid communication with the interface.
G01L 7/08 - Measuring the steady or quasi-steady pressure of a fluid or a fluent solid material by mechanical or fluid pressure-sensitive elements in the form of elastically-deformable gauges of the flexible-diaphragm type
G01L 19/06 - Means for preventing overload or deleterious influence of the measured medium on the measuring device or vice versa
A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
G01L 19/00 - Details of, or accessories for, apparatus for measuring steady or quasi-steady pressure of a fluent medium insofar as such details or accessories are not special to particular types of pressure gauges
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 5/021 - Measuring pressure in heart or blood vessels
61.
System and method for enhancing plasma acquisition at a plasma donation center
A method for engaging a donor includes receiving, in a server, donor information and donation data for the donor, and sending a first communication to the donor. The first communication may be sent to the donor after completion of a donation and the method may monitor a time period after the donation to determine when a predetermined period of time has passed. The method may then generate and send a second communication to the donor after the passage of the predetermined time period. The second communication may remind the donor of that the donor is eligible to donate again and may include a preferred date and time for the donor to return to donate again. The preferred date and time may be based, at least in part, on heuristic information about the donation center's productivity. The method may also generate/send an additional message requesting a referral from the donor.
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
A63F 13/79 - Game security or game management aspects involving player-related data, e.g. identities, accounts, preferences or play histories
G06Q 30/0207 - Discounts or incentives, e.g. coupons or rebates
G06Q 30/0226 - Incentive systems for frequent usage, e.g. frequent flyer miles programs or point systems
G06Q 50/00 - Information and communication technology [ICT] specially adapted for implementation of business processes of specific business sectors, e.g. utilities or tourism
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
H04L 67/12 - Protocols specially adapted for proprietary or special-purpose networking environments, e.g. medical networks, sensor networks, networks in vehicles or remote metering networks
62.
SYSTEM AND METHOD FOR CREATING CELL PROCESSING PROTOCOLS
A method for creating a custom cell processing protocol includes providing a cell processing device having a display, a blood component separation device, and a pump. The method may then select, using the display, a first and second processing phase. The first processing phase has a plurality of first processing phase parameters and the second processing phase has a plurality of second processing phase parameters. The method may then modify the first and second processing phase parameters using the display, and create a custom protocol algorithm. The algorithm may be based, at least in part, on the selected first and second processing phases and the modified first and second processing phase parameters
A61M 1/36 - Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation
A61M 1/34 - Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration, diafiltration
B04B 5/04 - Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
B04B 13/00 - Control arrangements specially designed for centrifugesProgramme control of centrifuges
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
G05B 13/02 - Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric
63.
SYSTEM AND METHOD FOR REMOTELY OBTAINING DONOR INFORMATION
A method for remotely obtaining donor information includes identifying a donor after receiving donor specific information from the donor at a remote location and retrieving, at a plasma center, a donor questionnaire based, at least in part, on the donor specific information. The method may then present at least one question from the questionnaire to the donor at the remote location and receive at least one response to question(s) from the donor. Upon receipt of the response(s), the method processes the response(s) at the plasma center and assesses a result of the processed responses to achieve a result assessment based on the at least one response. The assessment may be either a passing assessment or a non-passing assessment. The method may then encode, if the assessment is a passing assessment, the assessment and provide the donor with the encoded assessment.
G16H 10/65 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records stored on portable record carriers, e.g. on smartcards, RFID tags or CD
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
G06K 19/06 - Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
G06K 19/07 - Record carriers with conductive marks, printed circuits or semiconductor circuit elements, e.g. credit or identity cards with integrated circuit chips
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
G06K 7/14 - Methods or arrangements for sensing record carriers by electromagnetic radiation, e.g. optical sensingMethods or arrangements for sensing record carriers by corpuscular radiation using light without selection of wavelength, e.g. sensing reflected white light
G06K 9/00 - Methods or arrangements for reading or recognising printed or written characters or for recognising patterns, e.g. fingerprints
64.
HEALTH CARE PROVIDER DATA SYSTEMS PROCESSING AND ANALYTICS
A method for generating a directive for maintaining an objective includes integrating a control center system with a plurality of healthcare provider data systems and obtaining information from the healthcare provider data system(s). The method may then use artificial intelligence to correlate the obtained information against an identified business objective of a donation center and generate, using a heuristic model, a directive to the donation center(s) to achieve the identified business objective. The method may then present the directive a user and/or user system such that the directive may carried out.
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
G06Q 10/06 - Resources, workflows, human or project managementEnterprise or organisation planningEnterprise or organisation modelling
G06N 5/00 - Computing arrangements using knowledge-based models
A plasmapheresis bowl for the separation and collection of plasma includes a core and a feed tube that increase the bowl efficiency and reduce foaming within the plasma. The core may have a cylindrical body and a ledge located within the interior of the core. The ledge extends radially inward from the core and defines, at least partially, a collection chamber within the plasmapheresis bowl. The core also has ribs that extend above the top of core body and create flow paths that allow fluid to enter the interior of the cylindrical body and collection chamber. The feed tube has a flow path extending through it that fluidly connects an inlet port on the plasmapheresis centrifuge. A first skirt member on the feed tube has a smooth angled surface that helps to reduce foaming.
A volume measurement system for a fluid processing device includes a fluid container, an imaging unit, and a controller. The container includes a housing defining the structure of the fluid container, and a plurality of fluid chambers. The fluid chambers collect and/or store fluid from the fluid processing device, and each have a port that allows fluid to enter and/or exit the fluid chambers. The imaging unit takes images of the fluid chambers and is positioned to view a level of fluid in each of the chambers. The controller is in communication with the imaging unit and determines the volume of fluid within each of the fluid chambers based upon the viewed level of fluid in the fluid chambers.
G01L 19/00 - Details of, or accessories for, apparatus for measuring steady or quasi-steady pressure of a fluent medium insofar as such details or accessories are not special to particular types of pressure gauges
G01F 22/02 - Methods or apparatus for measuring volume of fluids or fluent solid material, not otherwise provided for involving measurement of pressure
67.
Y-connector for blood processing system and disposable set containing same
A tubing set for a blood processing system includes a first connector, a first tube, and a second tube. The first connector is configured to connect to a separation device within the blood processing system, and has a first inlet configured to be fluidly connected to an outlet of the separation device. The first connector also has an outlet and a second inlet. The first tube fluidly connects to the outlet and fluidly connects the separation device and a blood component storage container. The second tube is fluidly connected to the second inlet and fluidly connects the separation device and a saline storage container. The second tube may include a second connector that connects to the saline storage container.
A fleet management system includes apheresis devices and a fleet management device remotely located from and in communication with the apheresis devices. Each apheresis device has a controller, firmware and firmware settings. The fleet management device includes an interface to allow a user to interact with the fleet management device, a server and a processor. The server receives information regarding the firmware/firmware settings of each of the apheresis devices and a firmware file from the user and/or a remote repository. The processor processes the information to determine which of the apheresis devices requires an update to the firmware/firmware settings. The server then distributes the firmware file to each apheresis device that requires the update. The system may also develop a fleet model for one or more donation centers that includes a recommend quantity of devices for the location(s) and/or whether devices should be moved from one location to another.
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
G06F 8/71 - Version control Configuration management
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
70.
Detection of Reversal of an Anticoagulant Using a Clotting Assay
In some embodiments, the invention provides methods for detecting the reversal an anticoagulant at a therapeutically relevant amount or higher in a patient, including subjecting a sample of a control blood component (known not to contain the anticoagulant) to a clotting assay in the presence of an ecarin reagent to obtain a control ecarin clotting measurement; subjecting a sample of a control blood component (known not to contain the anticoagulant) to a clotting assay in the presence of a Factor Xa reagent to obtain a control Factor Xa clotting measurement; subjecting a sample of a blood component from a patient suspected to contain a reversal agent to a clotting assay in the presence of the ecarin reagent to obtain a patient ecarin clotting measurement; subjecting a sample of a blood component from the patient suspected to contain the reversal agent to a clotting assay in the presence of the Factor Xa reagent to obtain a patient Factor Xa clotting measurement; and comparing the control ecarin clotting measurement to the patient ecarin clotting measurement and comparing the control Factor Xa clotting measurement to the patient Factor Xa measurement.
A method for collecting plasma includes determining the weight and hematocrit of a donor, and inserting a venous-access device into the donor. The method then withdraws blood from the donor through a draw line connected to a blood component separation device, and introduces anticoagulant into the withdrawn blood. The blood component separation device separates the blood into a plasma component and a second blood component, and the plasma component is collected from the blood component separation device and into a plasma collection container. The method may then calculate (1) a percentage of anticoagulant in the collected plasma component, and (2) a volume of pure plasma collected within the plasma collection container. The volume of pure plasma may be based, at least in part, on the calculated percentage of anticoagulant. The method may continue until a target volume of pure plasma is collected within the plasma collection container.
A method for collecting plasma includes determining the weight, height, and hematocrit of a donor, and calculating a donor plasma volume and a target plasma collection volume. The target plasma collection volume is based on the donor plasma volume and a target percentage of plasma. The method then withdraws blood from the donor through a line connected to a blood component separation device, and introduces anticoagulant into the withdrawn blood. The blood component separation device separates the blood into a plasma component and a second blood component, and the plasma component is collected from the blood component separation device and into a plasma collection container. The method may then calculate the volume of pure plasma collected within the plasma collection container, and continue processing/collecting until the calculated volume of pure plasma equals the target plasma collection volume.
A cap removal device and a thrombelastography device having same are disclosed. The cap removal device comprises a drive part (1), a connection shaft (2), and a cap removal member (3). The connection shaft (2) can move upward when driven by the drive part (1). The cap removal member (3) has an end (31) and the other end (32); the end (31) is pivotally connected to the connection shaft (2), so that when the connection shaft (2) moves upward when driven by the drive part (1), the cap removal member (3) rotates, due to the upward movement, around a pivot point (4) located between the end (31) and the other end (32) of the cap removal member (3), so that the other end (32) of the cap removal member (3) moves downward to contact a cap (5) to be removed, thereby removing the cap (5). The thrombelastography device has the cap removal device, and thus can achieve the automatic removal of the cap (5) and the automated control on the drive part (1), thereby improving the cap removal efficiency and the test efficiency, and saving time of manually removing the cap.
A continuous flow centrifuge bowl includes a rotatable outer body, and a top and bottom core that are rotatable with the outer body. The bottom core has a wall extending proximally from a bottom wall. The proximally extending wall is radially outward from at least a portion of the top core and, together with the top core, defines a primary separation region in which initial separation of the whole blood occurs. The bowl may also have a secondary separation region located between the top core and the outer body, and a rotary seal that couples an inlet port and two outlet ports to the outer body. The inlet port may be connected to an inlet tube that extends distally into a whole blood introduction region. Additionally, one of the outlet ports may be connected to an extraction tube that extends into a region below the bottom core.
A bracket, a thrombelastography device, and a support system are disclosed. The device comprises: a fixed support part (101), a movable support part (102), and a connection part (103). The connection part comprises a first fixing connection member (1031) and a second fixing connection member (1032). The first fixing connection member is fixedly connected to the fixed support part; the second fixing connection member is fixedly connected to the movable support part; the first fixing connection member is connected to the second fixing connection member in point contact fashion, such that the first fixing connection member and the second fixing connection member can rotate relative to each other; the movable support part is fixedly connected to a supported object; when driven by the supported object, the movable support part rotates relative to the fixed support part by means of the point contact between the first fixing connection member and the second fixing connection member. The thrombelastography device comprises a rotational shaft and a bracket. The rotational resistance to the supported object when it rotates can be reduced.
G01N 33/49 - Physical analysis of biological material of liquid biological material blood
G01N 11/14 - Investigating flow properties of materials, e.g. viscosity or plasticityAnalysing materials by determining flow properties by moving a body within the material by using rotary bodies, e.g. vane
G01N 11/16 - Investigating flow properties of materials, e.g. viscosity or plasticityAnalysing materials by determining flow properties by moving a body within the material by measuring damping effect upon oscillatory body
G01N 33/86 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving blood coagulating time
A method for collecting plasma includes determining the weight, height, and hematocrit of a donor, and calculating a donor plasma volume and a target plasma collection volume. The target plasma collection volume is based on the donor plasma volume and a target percentage of plasma. The method then withdraws blood from the donor through a line connected to a blood component separation device, and introduces anticoagulant into the withdrawn blood. The blood component separation device separates the blood into a plasma component and a second blood component, and the plasma component is collected from the blood component separation device and into a plasma collection container. The method may then calculate the volume of pure plasma collected within the plasma collection container, and continue processing/collecting until the calculated volume of pure plasma equals the target plasma collection volume.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Downloadable and recorded computer software for use in
operation of blood and blood plasma processing equipment. Blood and blood plasma processing equipment for medical use.
A method for collecting plasma includes determining the weight and hematocrit of a donor, and inserting a venous-access device into the donor. The method then withdraws blood from the donor through a draw line connected to a blood component separation device, and introduces anticoagulant into the withdrawn blood. The blood component separation device separates the blood into a plasma component and a second blood component, and the plasma component is collected from the blood component separation device and into a plasma collection container. The method may then calculate (1) a percentage of anticoagulant in the collected plasma component, and (2) a volume of pure plasma collected within the plasma collection container. The volume of pure plasma may be based, at least in part, on the calculated percentage of anticoagulant. The method may continue until a target volume of pure plasma is collected within the plasma collection container.
09 - Scientific and electric apparatus and instruments
Goods & Services
Downloadable computer application software for mobile phones and computers, namely, downloadable software for use by potential blood or plasma donors to see donation history, find donation drives and schedule appointments, receive education about the donation process, complete health history questionnaires, receive notification of use of donated blood or plasma; downloadable computer application software for mobile phones and computers, namely, downloadable software for use by blood or plasma donation center operators for donation trend analysis, to target and identify donors and prospective donors for marketing message outreach via social media, e-mail, or SMS, conduct donor surveys, and for providing information about the donor to donation center workers to enhance the donor's in-center experience; computer application software for mobile phones and computers, namely, recorded software for use by potential blood or plasma donors to see donation history, find donation drives and schedule appointments, receive education about the donation process, complete health history questionnaires, receive notification of use of donated blood or plasma; computer application software for mobile phones and computers, namely, recorded software for use by blood or plasma donation center operators for donation trend analysis, to target and identify donors and prospective donors for marketing message outreach via social media, e-mail, or SMS, conduct donor surveys, and for providing information about the donor to donation center workers to enhance the donor's in-center experience
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
(1) Computer software for use in operation of blood and blood plasma processing equipment and not for use in imaging
(2) Blood and blood plasma processing equipment for medical use and not for use in imaging
85.
SYSTEM AND METHOD FOR CREATING CELL PROCESSING PROTOCOLS
A method for creating a custom cell processing protocol includes providing a cell processing device having a display, a blood component separation device, and a pump. The method may then select, using the display, a first and second processing phase. The first processing phase has a plurality of first processing phase parameters and the second processing phase has a plurality of second processing phase parameters. The method may then modify the first and second processing phase parameters using the display, and create a custom protocol algorithm. The algorithm may be based, at least in part, on the selected first and second processing phases and the modified first and second processing phase parameters
A controller for a blood processing device has a body that may dock and undock with a first blood processing device to connect the controller to the first blood processing device and disconnect the controller from the first blood processing device. A processor within the controller controls the first blood processing device when the controller is docked with the first blood processing device and remotely controls the first blood processing device when undocked. The controller also has a user interface that displays information regarding the first blood processing device and an ongoing apheresis procedure when the controller is docked to the first blood processing device and when the controller is undocked from the first blood processing device.
A method for engaging a donor includes receiving, in a server, donor information and donation data for the donor, and sending a first communication to the donor. The first communication may be sent to the donor after completion of a donation and the method may monitor a time period after the donation to determine when a predetermined period of time has passed. The method may then generate and send a second communication to the donor after the passage of the predetermined time period. The second communication may remind the donor of that the donor is eligible to donate again and may include a preferred date and time for the donor to return to donate again. The preferred date and time may be based, at least in part, on heuristic information about the donation center's productivity. The method may also generate/send an additional message requesting a referral from the donor.
G06Q 30/02 - MarketingPrice estimation or determinationFundraising
G06Q 30/0207 - Discounts or incentives, e.g. coupons or rebates
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
A method for generating a directive for maintaining an objective includes integrating a control center system with a plurality of healthcare provider data systems and obtaining information from the healthcare provider data system(s). The method may then use artificial intelligence to correlate the obtained information against an identified business objective of a donation center and generate, using a heuristic model, a directive to the donation center(s) to achieve the identified business objective. The method may then present the directive a user and/or user system such that the directive may carried out.
G06Q 10/0637 - Strategic management or analysis, e.g. setting a goal or target of an organisationPlanning actions based on goalsAnalysis or evaluation of effectiveness of goals
G16H 40/20 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management or administration of healthcare resources or facilities, e.g. managing hospital staff or surgery rooms
89.
APHERESIS DEVICES FLEET MANAGEMENT SYSTEM AND METHOD
A fleet management system includes apheresis devices and a fleet management device remotely located from and in communication with the apheresis devices. Each apheresis device has a controller, firmware and firmware settings. The fleet management device includes an interface to allow a user to interact with the fleet management device, a server and a processor. The server receives information regarding the firmware/firmware settings of each of the apheresis devices and a firmware file from the user and/or a remote repository. The processor processes the information to determine which of the apheresis devices requires an update to the firmware/firmware settings. The server then distributes the firmware file to each apheresis device that requires the update. The system may also develop a fleet model for one or more donation centers that includes a recommend quantity of devices for the location(s) and/or whether devices should be moved from one location to another.
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
A method for engaging a donor includes receiving, in a server, donor information and donation data for the donor, and sending a first communication to the donor. The first communication may be sent to the donor after completion of a donation and the method may monitor a time period after the donation to determine when a predetermined period of time has passed. The method may then generate and send a second communication to the donor after the passage of the predetermined time period. The second communication may remind the donor of that the donor is eligible to donate again and may include a preferred date and time for the donor to return to donate again. The preferred date and time may be based, at least in part, on heuristic information about the donation center's productivity. The method may also generate/send an additional message requesting a referral from the donor.
G06Q 50/00 - Information and communication technology [ICT] specially adapted for implementation of business processes of specific business sectors, e.g. utilities or tourism
G09B 23/28 - Models for scientific, medical, or mathematical purposes, e.g. full-sized device for demonstration purposes for medicine
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
91.
HEALTH CARE PROVIDER DATA SYSTEMS PROCESSING AND ANALYTICS
A method for generating a directive for maintaining an objective includes integrating a control center system with a plurality of healthcare provider data systems and obtaining information from the healthcare provider data system(s). The method may then use artificial intelligence to correlate the obtained information against an identified business objective of a donation center and generate, using a heuristic model, a directive to the donation center(s) to achieve the identified business objective. The method may then present the directive a user and/or user system such that the directive may carried out.
G06Q 50/00 - Information and communication technology [ICT] specially adapted for implementation of business processes of specific business sectors, e.g. utilities or tourism
92.
APHERESIS DEVICES FLEET MANAGEMENT SYSTEM AND METHOD
A fleet management system includes apheresis devices and a fleet management device remotely located from and in communication with the apheresis devices. Each apheresis device has a controller, firmware and firmware settings. The fleet management device includes an interface to allow a user to interact with the fleet management device, a server and a processor. The server receives information regarding the firmware/firmware settings of each of the apheresis devices and a firmware file from the user and/or a remote repository. The processor processes the information to determine which of the apheresis devices requires an update to the firmware/firmware settings. The server then distributes the firmware file to each apheresis device that requires the update. The system may also develop a fleet model for one or more donation centers that includes a recommend quantity of devices for the location(s) and/or whether devices should be moved from one location to another.
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
G16H 40/40 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the management of medical equipment or devices, e.g. scheduling maintenance or upgrades
G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
93.
SYSTEM AND METHOD FOR REMOTELY OBTAINING DONOR INFORMATION
A method for remotely obtaining donor information includes identifying a donor after receiving donor specific information from the donor at a remote location and retrieving, at a plasma center, a donor questionnaire based, at least in part, on the donor specific information. The method may then present at least one question from the questionnaire to the donor at the remote location and receive at least one response to question(s) from the donor. Upon receipt of the response(s), the method processes the response(s) at the plasma center and assesses a result of the processed responses to achieve a result assessment based on the at least one response. The assessment may be either a passing assessment or a non-passing assessment. The method may then encode, if the assessment is a passing assessment, the assessment and provide the donor with the encoded assessment.
G06Q 50/22 - Social work or social welfare, e.g. community support activities or counselling services
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
94.
SYSTEM AND METHOD FOR REMOTELY OBTAINING DONOR INFORMATION
A method for remotely obtaining donor information includes identifying a donor after receiving donor specific information from the donor at a remote location and retrieving, at a plasma center, a donor questionnaire based, at least in part, on the donor specific information. The method may then present at least one question from the questionnaire to the donor at the remote location and receive at least one response to question(s) from the donor. Upon receipt of the response(s), the method processes the response(s) at the plasma center and assesses a result of the processed responses to achieve a result assessment based on the at least one response. The assessment may be either a passing assessment or a non-passing assessment. The method may then encode, if the assessment is a passing assessment, the assessment and provide the donor with the encoded assessment.
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G06F 19/00 - Digital computing or data processing equipment or methods, specially adapted for specific applications (specially adapted for specific functions G06F 17/00;data processing systems or methods specially adapted for administrative, commercial, financial, managerial, supervisory or forecasting purposes G06Q;healthcare informatics G16H)
A controller for a blood processing device has a body that may dock and undock with a first blood processing device to connect the controller to the first blood processing device and disconnect the controller from the first blood processing device. A processor within the controller controls the first blood processing device when the controller is docked with the first blood processing device and remotely controls the first blood processing device when undocked. The controller also has a user interface that displays information regarding the first blood processing device and an ongoing apheresis procedure when the controller is docked to the first blood processing device and when the controller is undocked from the first blood processing device.
In some embodiments, the invention provides methods for detecting and/or classifying an anticoagulant at a therapeutically relevant amount or higher in a patient, including subjecting a sample of a control blood component (known not to contain the anticoagulant) to a clotting assay in the presence of a Factor Xa reagent to obtain a control clotting measurement; and subjecting a sample of a blood component from a patient suspected of having the anticoagulant to the clotting assay in the presence of the Factor Xa reagent to obtain a patient clotting measurement, wherein the patient clotting measurement sample greater than the control clotting measurement indicates the presence of the anticoagulant at a therapeutically relevant amount or higher in the patient. In some embodiments, the invention includes methods for classifying an anticoagulant as an anti-Factor Xa or a direct thrombin inhibitor anticoagulant using a clotting assay in the presence of an ecarin reagent.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
Downloadable and recorded computer software for use in operation of blood and blood plasma processing equipment blood and blood plasma processing equipment for medical use
A top for a plasma storage container includes a top body that defines the structure of the top and seals an opening of the plasma storage container. The top also includes a first opening and a vent opening extending through the top body. A valve mechanism is located at least partially within the top body and includes an aperture therethrough. The aperture opens upon connection of a blunt cannula to provide access to the interior of the plasma storage container. The top also includes a vent filter. The vent filter allows air to vent through the vent opening during plasma collection.
A tubing set for a blood processing system includes a first connector, a first tube, and a second tube. The first connector is configured to connect to a separation device within the blood processing system, and has a first inlet configured to be fluidly connected to an outlet of the separation device. The first connector also has an outlet and a second inlet. The first tube fluidly connects to the outlet and fluidly connects the separation device and a blood component storage container. The second tube is fluidly connected to the second inlet and fluidly connects the separation device and a saline storage container. The second tube may include a second connector that connects to the saline storage container.
A plasmapheresis bowl for the separation and collection of plasma includes a core and a feed tube that increase the bowl efficiency and reduce foaming within the plasma. The core may have a cylindrical body and a ledge located within the interior of the core. The ledge extends radially inward from the core and defines, at least partially, a collection chamber within the plasmapheresis bowl. The core also has ribs that extend above the top of core body and create flow paths that allow fluid to enter the interior of the cylindrical body and collection chamber. The feed tube has a flow path extending through it that fluidly connects an inlet port on the plasmapheresis centrifuge. A first skirt member on the feed tube has a smooth angled surface that helps to reduce foaming.
