Class of quinones for use in the treatment restoring, normalizing and/or improving ATP in cells lacking mitochondria, such as red blood cells. Specific example is use in the treatment of red blood cell enzymopathies, especially in the treatment of defects in red blood cell metabolism such as defects in red blood cell glycolysis. The treatment increases ATP in non-mitochondrial cells. Thus, the present invention relates to a class of quinones for use in the treatment of diseases or conditions associated with or caused by defects in red blood cell glycolysis.
A61K 31/122 - Ketones having the oxygen atom directly attached to a ring, e.g. quinones, vitamin K1, anthralin
A61K 31/343 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
Classes of quinones for use in the treatment of red blood cell enzymopathologies. The treatment increases ATP in non-mitochondrial cells. Thus, the present invention relates to classes of quinones for use in the treatment of diseases or conditions associated with or caused by defects in red blood cell glycolysis.
A61K 31/122 - Ketones having the oxygen atom directly attached to a ring, e.g. quinones, vitamin K1, anthralin
A61K 31/343 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
The present invention relates to
i) KL1333 for use in the treatment of mitochondrial diseases or diseases associated with mitochodrial diseases such as fatigue such as fatigue syndrome and fatigue associated with a disease or muscle weakness associated with a mitochondrial disease,
ii) KL1333 for use in a dosage regime for the treatment of one or more of fatigue, muscle weakness or a mitochondrial disease,
iii) use of blood lactate (mM)/pyruvate (mM) ratio as biomarker of KL1333 treatment effect, wherein a decrease in ratio indicates that the treatment is effective, and
iv) use of serum niacinamide and/or xanthine as biomarker of KL1333 treatment effect, wherein an increase in the ratio of niacinamide and/or xanthine concentrations indicates that the treatment is effective and the ratio of niacinamide and/or xanthine concentrations is (serum concentration at test day)/(serum concentration at the start of the treatment).
The present invention provides a novel isolated succinate prodrug as the free compound or a salt, hydrate, solvate or complex thereof being cell permeable and aimed for increasing the ATP-production in mitochondria. The compound is useful in the medical treatment of a range of diseases, in nutritional supplements, nutricosmetics and in cosmetics.
C07C 327/30 - Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms, not being part of nitro or nitroso groups
The present invention relates to i) KL1333 for use in the treatment of mitochondrial diseases or diseases associated with mitochodrial diseases such as fatigue such as fatigue syndrome and fatigue associated with a disease or muscle weakness associated with a mitochondrial disease, ii) KL1333 for use in a dosage regime for the treatment of one or more of fatigue, muscle weakness or a mitochondrial disease, iii) use of blood lactate (mM)Zpyruvate (mM) ratio as biomarker of KL1333 treatment effect, wherein a decrease in ratio indicates that the treatment is effective, and iv) use of serum niacinamide and/or xanthine as biomarker of KL1333 treatment effect, wherein an increase in the ratio of niacinamide and/or xanthine concentrations indicates that the treatment is effective and the ratio of niacinamide and/or xanthine concentrations is (serum concentration at test day)/(serum concentration at the start of the treatment).
The present invention relates to i) KL1333 for use in the treatment of mitochondrial diseases or diseases associated with mitochodrial diseases such as fatigue such as fatigue syndrome and fatigue associated with a disease or muscle weakness associated with a mitochondrial disease, ii) KL1333 for use in a dosage regime for the treatment of one or more of fatigue, muscle weakness or a mitochondrial disease, iii) use of blood lactate (mM)Zpyruvate (mM) ratio as biomarker of KL1333 treatment effect, wherein a decrease in ratio indicates that the treatment is effective, and iv) use of serum niacinamide and/or xanthine as biomarker of KL1333 treatment effect, wherein an increase in the ratio of niacinamide and/or xanthine concentrations indicates that the treatment is effective and the ratio of niacinamide and/or xanthine concentrations is (serum concentration at test day)/(serum concentration at the start of the treatment).
The present invention provides a novel isolated succinate prodrug as the free com-pound or a salt, hydrate, solvate or complex thereof being cell permeable and aimed for increasing the ATP-production in mitochondria. The compound is useful in the medical treatment of a range of diseases, in nutritional supplements, nutricosmetics and in cosmetics.
C07C 327/30 - Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms, not being part of nitro or nitroso groups
The present invention provides novel cell-permeable succinates and cell permeable precursors of succinate aimed at increasing ATP-production in mitochondria. The main part of ATP produced and utilized in the eukaryotic cell originates from mitochondrial oxidative phosphorylation, a process to which high-energy electrons are provided by the Kreb's cycle. Not all Kreb's cycle intermediates are readily permeable to the cellular membrane, one of them being succinate. The provision of the novel cell permeable succinates is envisaged to allow passage over the cellular membrane and thus the cell permeable succinates can be used to enhance mitochondrial ATP-output.
A61K 31/265 - Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
A61K 31/22 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
C07D 211/76 - Oxygen atoms attached in position 2 or 6
A61P 11/00 - Drugs for disorders of the respiratory system
A61P 9/00 - Drugs for disorders of the cardiovascular system
A61P 21/00 - Drugs for disorders of the muscular or neuromuscular system
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
C07C 327/28 - Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
C07C 327/30 - Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms, not being part of nitro or nitroso groups
C07C 327/32 - Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
C07C 327/34 - Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups with amino groups bound to the same hydrocarbon radicals
9.
SUCCINATE PRODRUG, COMPOSITIONS CONTAINING THE SUCCINATE PRODRUG AND USES THEREOF
The present invention provides a novel isolated succinate prodrug as the free com- pound or a salt, hydrate, solvate or complex thereof being cell permeable and aimed for increasing the ATP-production in mitochondria. The compound is useful in the medical treatment of a range of diseases, in nutritional supplements, nutricosmetics and in cosmetics.
C07C 327/30 - Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms, not being part of nitro or nitroso groups
A23L 33/10 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives
A61K 8/46 - Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
A61K 31/265 - Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
10.
SUCCINATE PRODRUG, COMPOSITIONS CONTAINING THE SUCCINATE PRODRUG AND USES THEREOF
The present invention provides a novel isolated succinate prodrug as the free com- pound or a salt, hydrate, solvate or complex thereof being cell permeable and aimed for increasing the ATP-production in mitochondria. The compound is useful in the medical treatment of a range of diseases, in nutritional supplements, nutricosmetics and in cosmetics.
C07C 327/30 - Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms, not being part of nitro or nitroso groups
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16.
Use of sanglifehrin macrocyclic analogues as anticancer compounds
The present invention relates to sanglifehrin macrocyclic analogues according to Formula (I),
particularly for use in treatment of cancer, especially liver cancer.
A61K 31/704 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
A61K 39/395 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum
C07D 237/04 - Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
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01 - Chemical and biological materials for industrial, scientific and agricultural use
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pharmaceutical preparations for medical use consisting of a
cyclosporin as active agent and diluents to treat stroke,
traumatic brain or spinal cord injury, and other acute or
chronic neurological and neurosurgical conditions;
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cyclosporin or another cyclophilin inhibitor as active agent
and diluents to treat stroke, traumatic brain or spinal cord
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phosphates for veterinary purposes; plasters, materials for
dressings; potassium salts for medical purposes; potassium
salts for veterinary purposes; preparations for destroying
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purposes; salts for medical purposes; salts for veterinary
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pills; sodium salts for medical purposes; sodium salts for
veterinary purposes; sulfonamides [medicines]; tinctures for
medical purposes; tinctures for veterinary purposes; tonics
[medicines]; tonics for medical use; tonics for veterinary
use; vaccines; vaccines for human use; veterinary
preparations; veterinary preparations and substances;
veterinary vaccines; drugs and pharmaceutical preparations
for acute and chronic neurological diseases and conditions
(including preventive treatment); diagnostics for medical
purposes. Apparatus and instruments for measuring, testing and
analyzing biological samples, blood or other bodily fluids;
chromatography apparatus for laboratory use; diagnostic
apparatus, not for medical purposes; DNA chips; laboratory
apparatus and instruments; quantity indicators respirometer;
scientific research and laboratory apparatus, educational
apparatus and simulators; chemical apparatus and
instruments; electrodes for laboratory research. Apparatus for analyzing substances [for medical use];
apparatus for blood tests [for medical use]; apparatus for
use in medical analysis; blood testing apparatus; blood
testing equipment; electrodes for medical use; medical
analytical apparatus for medical purposes; medical apparatus
and instruments; medical diagnostic apparatus for medical
purposes; medical diagnostic instruments; probes for medical
purposes; probes for veterinary purposes; medical
electrodes; electrodes for use in connection with medical
apparatus; electrodes for cardiology; electrodes for
veterinary use, namely medical electrodes. Analysis of human tissues for medical research;
bacteriological analysism, consultation; biochemical
research; biological analysis; biological laboratory
services; biological research and analysis; biological
research, clinical research and medical research; biological
sample analysis for scientific and medical research
purposes; biological samples, blood or other bodily fluids
analysis services for scientific and medical research
purposes; biotechnology research; blood analysis services;
blood analysis services for scientific and medical re-search
purposes; chemical analysis and research; chemical research
and analysis ser-vices; chemistry consultancy services;
clinical research; clinical research and trials; clinical
trials; conducting clinical trials; conducting clinical
trials for others; conducting clinical trials for
pharmaceutical products; conducting early evaluations in the
field of new pharmaceuticals; consultancy in the field of
cosmetics, namely, consultancy in connection with the
quality inspection, research and development of cosmetic
products and medicated cosmetic products; consultancy in the
field of sanitary research for medical purpose; consultancy
in pharmaceutical, pharmacogenetics, medical chemistry,
veterinary, for research purposes; consultancy services in
the field of biology; consultancy services in the field of
biotechnology; consulting on pharmacogenetics; cosmetic
research; cosmetic research and analysis services; cosmetic
research services and laboratory analysis services in the
field of cosmetics; design and development of computer
hardware and software; design and development of diagnostic
apparatus and instruments; design and development of medical
diagnostic apparatus and instruments; development, testing
and consultancy services in the fields of biotechnology,
pharmaceutical, medical, sanitary, veterinary, chemistry,
biology and pharmacogenetics; dna analysis for scientific
and medical research purposes; drug and pharmaceutical
discovery, testing and development services; drug discovery
services; industrial analysis and research services;
laboratory research services relating to pharmaceuticals;
medical and veterinary research and development and
consultancy related there-to; medical laboratory services;
medical research; pharmaceutical product evaluation;
pharmaceutical products development; pharmaceutical research
and development; pharmaceutical research services; providing
information in connection with all the aforementioned
services; providing medical and veterinary testing services
in the field of research relating to medicines, drug
discovery, drug development and drug screening and
consultancy related thereto; research and development in the
field of biotechnology; research and development in the
field of microorganisms and cells; research and development
in the pharmaceutical and biotechnology fields; research and
development services; research and testing; research of
pharmaceuticals; research relating to biotechnology;
research relating to pharmaceuticals; research, development,
and testing services, and consultancy related thereto, in
the fields of biotechnology, pharmaceutical, medical,
sanitary, veterinary, chemistry, biology and
pharmacogenetics; research, development, and testing
services, and consultancy related thereto, in the fields of
biotechnology, pharmaceuticals, sanitary products,
chemistry, biology and pharmacogenetics; research,
development, testing and consultancy services in the fields
of biotechnology, pharmaceutical, medical, sanitary,
veterinary, chemistry, biology and pharmacogenetics;
research, development, testing, scientific consultancy
services in the fields of biotechnology, pharmaceutical,
medical, sanitary, veterinary, chemistry, biology and
pharmacogenetics; research, research in the field of
environmental protection; re-search, test and development of
sanitary, pharmaceutical, medical, medicinal chemical,
veterinary preparations; research, test and development of
biotechnical, biological preparations; research, testing and
development in the field of diagnostic preparations;
research, testing and development in the field of diagnostic
preparations; research, testing and development of
diagnostic preparations for medical purpose; scientific
analysis; scientific and technological services and research
and design relating thereto; scientific laboratory
ser-vices; scientific research; scientific research relating
to cosmetics; testing of pharmaceuticals; toxicity analysis;
toxicity testing for research purposes; veterinary
laboratory services. Agriculture, horticulture and forestry service; analysis of
human serum for medical treatment; analysis of human tissues
for medical treatment; consultancy in the dental medicare
field; consultancy in the field of cosmetics; consultancy in
the field of cosmetics, namely consultancy in connection
with the selection of cosmetic products and medicated
cosmetic products; consultancy in the field of
pharmacogenetics; consultancy in the medical field (other
than dentistry); drug screening for medical purposes; health
care; health care services; hygienic and beauty care for
human beings or animals; medical and surgical diagnostic
services; medical and surgical diagnostic services; medical
consultancy in the field of pharmacogenetics; medical
consultancy services; medical diagnostic services; medical
services; medical testing for diagnostic or treatment
purposes; pharmaceutical consultancy services; providing
information in connection with all the aforementioned
services; rental of ultrasonic diagnostic apparatus; therapy
services; veterinary consultancy services; veterinary
services.
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Esters for veterinary use; esters for veterinary purposes;
esters for foodstuffs, not for pharmaceutical purposes. Acetates for pharmaceutical purposes; acids for
pharmaceutical purposes; adjuvants for medical purposes;
aldehydes for pharmaceutical purposes; alginates for
pharmaceutical purposes; amino acids for medical purposes;
amino acids for veterinary purposes; antibiotics;
antidiabetic pharmaceuticals; antioxidant pills;
antioxidants; antitumor drugs; appetite suppressant pills;
appetite suppressants; appetite suppressants for medical
purposes; appetite suppressants for veterinary purposes;
bacterial preparations for medical use; bacterial
preparations for veterinary use; bacteriological culture
mediums; bacteriological preparations for medical purposes;
bacteriological preparations for medical use;
bacteriological preparations for veterinary purposes;
bacteriological preparations for veterinary use; biological
preparations for medical purposes; biological preparations
for the treatment of cancer; biological preparations for
veterinary purposes; biological tissue cultures for medical
purposes; biological tissue cultures for veterinary
purposes; biological tissues for implantation; bouillons for
bacteriological cultures; cachets for pharmaceutical
preparations; cachets for veterinary preparations; capsules
for medicines; castor oil for medical purposes; cellulose
ethers for pharmaceutical purposes; chemical preparations
for medical purposes; chemical preparations for
pharmaceutical purposes; chemical preparations for
veterinary purposes; chemicopharmaceutical preparations;
cytostatic drugs for medical purposes; decoctions for
medicinal herb; decoctions for pharmaceutical purposes;
dental wax; diagnostic biomarker reagents for medical
purposes; diagnostic biomarker reagents for veterinary
purposes; diagnostic preparations; diagnostic preparations
for medical use; diagnostic preparations for veterinary use;
diagnostic preparations for medical purposes; diagnostic
preparations for veterinary purposes; diagnostic
radiopharmaceutical preparations; dietary supplements for
animals; dietary supplements for humans; dietetic food and
substances adapted for medical or veterinary use, food for
babies; dietetic food and substances adapted for medical or
veterinary use; dietetic substances adapted for medical use,
food for babies; digestive enzymes; disinfectants; drugs for
medical purposes; elixirs [pharmaceutical preparations];
enzyme dietary supplements; enzyme preparations for medical
purposes; enzyme preparations for veterinary purposes;
enzymes for medical purposes; enzymes for veterinary
purposes; esters for pharmaceutical use; ethers for
pharmaceutical purposes; ferments for pharmaceutical
purposes; ferments for pharmaceutical use; ferments for
veterinary purposes; ferments for veterinary use; food
esters for pharmaceutical purposes; formic aldehyde for
pharmaceutical purposes; formic aldehyde for veterinary
purposes; fungicides, herbicides; in vitro diagnostic
preparations for medical use; lotions for medical purposes;
lotions for pharmaceutical purposes; lotions for veterinary
purposes; material for stopping teeth; material for stopping
teeth, dental wax; media for bacteriological cultures;
medical and veterinary preparations and articles; medical
preparations; medical preparations for slimming purposes;
medical vaccines; medicated animal feed; medicinal drinks;
medicinal infusions; medicinal oils; medicines and
pharmaceutical preparations for neurosurgical conditions,
brain damage, operations and similar; medicines and
pharmaceutical preparations for neurosurgical conditions,
brain damage and brain operations; medicines and
pharmaceutical preparations for the treatment of
neurosurgical conditions, brain damage, brain operations and
other physical and neurological ailments of the brain;
medicines and pharmaceutical preparations for the treatment
of neurosurgical conditions, namely, for brain damage and
for use in brain operations and other physical and
neurological ailments of the brain; medicines and
pharmaceutical preparations for use as immunosuppressive
agents, for example for organ transplant or other medical
(and clinical) uses of immunosuppressive agents or
preparations; medicines and pharmaceutical preparations for
use as immunosuppressive agents in organ transplants or
other medical and clinical uses of immunosuppressive agents
and preparations; medicines and pharmaceutical preparations
for use as immunosuppressive agents, for example organ
transplant or other uses of immunosuppressive agents;
medicines and pharmaceutical preparations for use within the
area of neurological intensive care; medicines for animals;
medicines for human purposes; medicines for veterinary
purposes; mixed biological preparations for medical
purposes; mixed biological preparations for veterinary
purposes; nutritional supplements; nutritional supplements
for livestock feed; ointments for medical purposes;
pharmaceutical and veterinary preparations; pharmaceutical
and veterinary preparations, namely, medicines and
pharmaceutical preparations for the treatment and prevention
of acute and chronic neurological illnesses and conditions;
pharmaceutical and veterinary preparations, namely,
medicines and pharmaceutical preparations for acute and
chronic neurological illnesses and conditions and for
preventative treatment; pharmaceutical drugs; pharmaceutical
preparations; pharmaceutical preparations acting on the
central nervous system; pharmaceutical preparations and
other preparations for destroying vermin, fungicides,
herbicides; pharmaceutical preparations and substances;
pharmaceutical preparations and substances for the
prevention of cancer; pharmaceutical preparations and
substances for the treatment of cancer; pharmaceutical
preparations and substances for use in oncology;
pharmaceutical preparations for activating cellular
function; pharmaceutical preparations for animals;
pharmaceutical preparations for human use; pharmaceutical
preparations for medical purposes and veterinary purposes;
pharmaceutical preparations for medical use consisting of a
cyclosporin as active agent and diluents to treat stroke,
traumatic brain or spinal cord injury, and other acute or
chronic neurological and neurosurgical conditions;
pharmaceutical preparations for medical use consisting of a
cyclosporin or another cyclophilin inhibitor as active agent
and diluents to treat stroke, traumatic brain or spinal cord
injury, and other acute or chronic neurological and
neurosurgical conditions; pharmaceutical preparations for
skin care; pharmaceutical preparations for suppressing
tumors; pharmaceutical preparations for the prevention of
diseases of the nervous system; pharmaceutical preparations
for the prevention of diseases of the metabolic system;
pharmaceutical preparations for the prevention of disorders
of the metabolic system; pharmaceutical preparations for the
prevention of disorders of the nervous system;
pharmaceutical preparations for the prevention of tumours;
pharmaceutical preparations for the treatment of cancer;
pharmaceutical preparations for the treatment of central
nervous system [cns] diseases; pharmaceutical preparations
for the treatment of diseases caused by bacteria;
pharmaceutical preparations for the treatment of diseases of
the metabolic system; pharmaceutical preparations for the
treatment of disorders of the metabolic system;
pharmaceutical preparations for the treatment of kidney
diseases; pharmaceutical preparations for the treatment of
kidney disorders; pharmaceutical preparations for the
treatment of parkinson's disease; pharmaceutical
preparations for the treatment of tumours; pharmaceutical
preparations for the treatment of viral diseases;
pharmaceutical preparations for treating diabetes;
pharmaceutical preparations for treating heatstroke;
pharmaceutical preparations for treating malignant tumors;
pharmaceutical preparations for treating metabolic
disorders; pharmaceutical preparations for treating
peripheral nervous system disorders; pharmaceutical
preparations for use as immunosuppressive agents;
pharmaceutical preparations for use in chemotherapy;
pharmaceutical preparations for use in oncology;
pharmaceutical preparations for use in organ
transplantation; pharmaceutical preparations for use in
tissue transplantation; pharmaceutical preparations for use
within the area of neurological intensive care;
pharmaceutical preparations for veterinary use;
pharmaceuticals; pharmaceuticals, medical and veterinary
preparations; phosphates for pharmaceutical purposes;
phosphates for veterinary purposes; plasters, materials for
dressings; potassium salts for medical purposes; potassium
salts for veterinary purposes; preparations for destroying
vermin; quinine for medical purposes; quinine for veterinary
purposes; salts for medical purposes; salts for veterinary
purposes; sanitary preparations for medical purposes;
sanitary preparations for veterinary purposes; slimming
pills; sodium salts for medical purposes; sodium salts for
veterinary purposes; sulfonamides [medicines]; tinctures for
medical purposes; tinctures for veterinary purposes; tonics
[medicines]; tonics for medical use; tonics for veterinary
use; vaccines; vaccines for human use; veterinary
preparations; veterinary preparations and substances;
veterinary vaccines; drugs and pharmaceutical preparations
for acute and chronic neurological diseases and conditions
(including preventive treatment); diagnostics for medical
purposes. Apparatus and instruments for measuring, testing and
analyzing biological samples, blood or other bodily fluids;
chromatography apparatus for laboratory use; diagnostic
apparatus, not for medical purposes; DNA chips; laboratory
apparatus and instruments; quantity indicators respirometer;
scientific research and laboratory apparatus, educational
apparatus and simulators; chemical apparatus and
instruments; electrodes for laboratory research. Apparatus for analyzing substances [for medical use];
apparatus for blood tests [for medical use]; apparatus for
use in medical analysis; blood testing apparatus; blood
testing equipment; electrodes for medical use; medical
analytical apparatus for medical purposes; medical apparatus
and instruments; medical diagnostic apparatus for medical
purposes; medical diagnostic instruments; probes for medical
purposes; probes for veterinary purposes; medical
electrodes; electrodes for use in connection with medical
apparatus; electrodes for cardiology; electrodes for
veterinary use, namely medical electrodes. Analysis of human tissues for medical research;
bacteriological analysism, consultation; biochemical
research; biological analysis; biological laboratory
services; biological research and analysis; biological
research, clinical research and medical research; biological
sample analysis for scientific and medical research
purposes; biological samples, blood or other bodily fluids
analysis services for scientific and medical research
purposes; biotechnology research; blood analysis services;
blood analysis services for scientific and medical re-search
purposes; chemical analysis and research; chemical research
and analysis ser-vices; chemistry consultancy services;
clinical research; clinical research and trials; clinical
trials; conducting clinical trials; conducting clinical
trials for others; conducting clinical trials for
pharmaceutical products; conducting early evaluations in the
field of new pharmaceuticals; consultancy in the field of
cosmetics, namely, consultancy in connection with the
quality inspection, research and development of cosmetic
products and medicated cosmetic products; consultancy in the
field of sanitary research for medical purpose; consultancy
in pharmaceutical, pharmacogenetics, medical chemistry,
veterinary, for research purposes; consultancy services in
the field of biology; consultancy services in the field of
biotechnology; consulting on pharmacogenetics; cosmetic
research; cosmetic research and analysis services; cosmetic
research services and laboratory analysis services in the
field of cosmetics; design and development of computer
hardware and software; design and development of diagnostic
apparatus and instruments; design and development of medical
diagnostic apparatus and instruments; development, testing
and consultancy services in the fields of biotechnology,
pharmaceutical, medical, sanitary, veterinary, chemistry,
biology and pharmacogenetics; dna analysis for scientific
and medical research purposes; drug and pharmaceutical
discovery, testing and development services; drug discovery
services; industrial analysis and research services;
laboratory research services relating to pharmaceuticals;
medical and veterinary research and development and
consultancy related there-to; medical laboratory services;
medical research; pharmaceutical product evaluation;
pharmaceutical products development; pharmaceutical research
and development; pharmaceutical research services; providing
information in connection with all the aforementioned
services; providing medical and veterinary testing services
in the field of research relating to medicines, drug
discovery, drug development and drug screening and
consultancy related thereto; research and development in the
field of biotechnology; research and development in the
field of microorganisms and cells; research and development
in the pharmaceutical and biotechnology fields; research and
development services; research and testing; research of
pharmaceuticals; research relating to biotechnology;
research relating to pharmaceuticals; research, development,
and testing services, and consultancy related thereto, in
the fields of biotechnology, pharmaceutical, medical,
sanitary, veterinary, chemistry, biology and
pharmacogenetics; research, development, and testing
services, and consultancy related thereto, in the fields of
biotechnology, pharmaceuticals, sanitary products,
chemistry, biology and pharmacogenetics; research,
development, testing and consultancy services in the fields
of biotechnology, pharmaceutical, medical, sanitary,
veterinary, chemistry, biology and pharmacogenetics;
research, development, testing, scientific consultancy
services in the fields of biotechnology, pharmaceutical,
medical, sanitary, veterinary, chemistry, biology and
pharmacogenetics; research, research in the field of
environmental protection; re-search, test and development of
sanitary, pharmaceutical, medical, medicinal chemical,
veterinary preparations; research, test and development of
biotechnical, biological preparations; research, testing and
development in the field of diagnostic preparations;
research, testing and development in the field of diagnostic
preparations; research, testing and development of
diagnostic preparations for medical purpose; scientific
analysis; scientific and technological services and research
and design relating thereto; scientific laboratory
ser-vices; scientific research; scientific research relating
to cosmetics; testing of pharmaceuticals; toxicity analysis;
toxicity testing for research purposes; veterinary
laboratory services. Agriculture, horticulture and forestry service; analysis of
human serum for medical treatment; analysis of human tissues
for medical treatment; consultancy in the dental medicare
field; consultancy in the field of cosmetics; consultancy in
the field of cosmetics, namely consultancy in connection
with the selection of cosmetic products and medicated
cosmetic products; consultancy in the field of
pharmacogenetics; consultancy in the medical field (other
than dentistry); drug screening for medical purposes; health
care; health care services; hygienic and beauty care for
human beings or animals; medical and surgical diagnostic
services; medical and surgical diagnostic services; medical
consultancy in the field of pharmacogenetics; medical
consultancy services; medical diagnostic services; medical
services; medical testing for diagnostic or treatment
purposes; pharmaceutical consultancy services; providing
information in connection with all the aforementioned
services; rental of ultrasonic diagnostic apparatus; therapy
services; veterinary consultancy services; veterinary
services.
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
esters for foodstuffs, not for pharmaceutical purposes. Fungicides, herbicides; preparations for destroying vermin, fungicides, herbicides. Apparatus and instruments for measuring, testing and analyzing biological samples, blood or other bodily fluids, not for medical purposes; chromatography apparatus for laboratory use; diagnostic apparatus, not for medical purposes; DNA chips; laboratory apparatus and instruments; quantity indicators respirometer; scientific research and laboratory apparatus, educational apparatus and simulators; electrodes for laboratory research. Consultancy in the field of cosmetics, namely, consultancy in connection with the quality inspection, research and development of cosmetic products and medicated cosmetic products; Cosmetic research; Cosmetic research and analysis services; Cosmetic research services and laboratory analysis services in the field of cosmetics; Design and development of computer hardware and software; scientific research relating to cosmetics. Agriculture, horticulture and forestry service; consultancy in the field of cosmetics; consultancy in the field of cosmetics, namely consultancy in connection with the selection of cosmetic products and medicated cosmetic products; hygienic and beauty care for human beings or animals; providing information in connection with all the aforementioned services; rental of ultrasonic diagnostic apparatus; therapy services.
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
esters for foodstuffs, not for pharmaceutical purposes. Acetates for pharmaceutical purposes; acids for pharmaceutical purposes; adjuvants for medical purposes; aldehydes for pharmaceutical purposes; alginates for pharmaceutical purposes; amino acids for medical purposes; amino acids for veterinary purposes; antibiotics; Antidiabetic pharmaceuticals; antioxidant pills; antioxidants; Antitumor drugs; appetite suppressant pills; appetite suppressants; appetite suppressants for medical purposes; appetite suppressants for veterinary purposes; bacterial preparations for medical use; bacterial preparations for veterinary use; bacteriological culture mediums; bacteriological preparations for medical purposes; bacteriological preparations for medical use; bacteriological preparations for veterinary purposes; bacteriological preparations for veterinary use; Biological preparations for medical purposes; biological preparations for the treatment of cancer; biological preparations for veterinary purposes; biological tissue cultures for medical purposes; biological tissue cultures for veterinary purposes; biological tissues for implantation; bouillons for bacteriological cultures; cachets for pharmaceutical preparations; cachets for veterinary preparations; capsules for medicines; castor oil for medical purposes; cellulose ethers for pharmaceutical purposes; chemical preparations for medical purposes; Chemical preparations for pharmaceutical purposes; chemical preparations for veterinary purposes; chemicopharmaceutical preparations; Cytostatic drugs for medical purposes; decoctions for medicinal herb; decoctions for pharmaceutical purposes; Dental wax; diagnostic biomarker reagents for medical purposes; diagnostic biomarker reagents for veterinary purposes; diagnostic preparations; diagnostic preparations for medical use; diagnostic preparations for veterinary use; diagnostic preparations for medical purposes; diagnostic preparations for veterinary purposes; diagnostic radiopharmaceutical preparations; dietary supplements for animals; dietary supplements for humans; Dietetic food and substances adapted for medical or veterinary use, food for babies; dietetic food and substances adapted for medical or veterinary use; Dietetic substances adapted for medical use, food for babies; Digestive enzymes; Disinfectants; drugs for medical purposes; elixirs [pharmaceutical preparations]; enzyme dietary supplements; enzyme preparations for medical purposes; enzyme preparations for veterinary purposes; enzymes for medical purposes; enzymes for veterinary purposes; esters for pharmaceutical use; ethers for pharmaceutical purposes; ferments for pharmaceutical purposes; ferments for pharmaceutical use; ferments for veterinary purposes; ferments for veterinary use; food esters for pharmaceutical purposes; formic aldehyde for pharmaceutical purposes; formic aldehyde for veterinary purposes; Fungicides, herbicides; in vitro diagnostic preparations for medical use; lotions for medical purposes; lotions for pharmaceutical purposes; lotions for veterinary purposes; Material for stopping teeth; Material for stopping teeth, dental wax; media for bacteriological cultures; Medical and veterinary preparations and articles; medical preparations; medical preparations for slimming purposes; medical vaccines; medicated animal feed; medicinal drinks; medicinal infusions; medicinal oils; Medicines and pharmaceutical preparations for neurosurgical conditions, brain damage, operations and similar; Medicines and pharmaceutical preparations for neurosurgical conditions, brain damage and brain operations; Medicines and pharmaceutical preparations for the treatment of neurosurgical conditions, brain damage, brain operations and other physical and neurological ailments of the brain; Medicines and pharmaceutical preparations for the treatment of neurosurgical conditions, namely, for brain damage and for use in brain operations and other physical and neurological ailments of the brain; Medicines and pharmaceutical preparations for use as immunosuppressive agents, for example for organ transplant or other medical (and clinical) uses of immunosuppressive agents or preparations; Medicines and pharmaceutical preparations for use as immunosuppressive agents in organ transplants or other medical and clinical uses of immunosuppressive agents and preparations; Medicines and pharmaceutical preparations for use as immunosuppressive agents, for example organ transplant or other uses of immunosuppressive agents; Medicines and pharmaceutical preparations for use within the area of neurological intensive care; Medicines for animals; Medicines for human purposes; medicines for veterinary purposes; mixed biological preparations for medical purposes; mixed biological preparations for veterinary purposes; nutritional supplements; Nutritional supplements for livestock feed; ointments for medical purposes; Pharmaceutical and veterinary preparations; Pharmaceutical and veterinary preparations, namely, medicines and pharmaceutical preparations for the treatment and prevention of acute and chronic neurological illnesses and conditions; Pharmaceutical and veterinary preparations, namely, medicines and pharmaceutical preparations for acute and chronic neurological illnesses and conditions and for preventative treatment; Pharmaceutical drugs; pharmaceutical preparations; Pharmaceutical preparations acting on the central nervous system; Pharmaceutical preparations and other preparations for destroying vermin, fungicides, herbicides; Pharmaceutical preparations and substances; Pharmaceutical preparations and substances for the prevention of cancer; Pharmaceutical preparations and substances for the treatment of cancer; Pharmaceutical preparations and substances for use in oncology; Pharmaceutical preparations for activating cellular function; Pharmaceutical preparations for animals; Pharmaceutical preparations for human use; Pharmaceutical preparations for medical purposes and veterinary purposes; Pharmaceutical preparations for medical use consisting of a cyclosporin as active agent and diluents to treat stroke, traumatic brain or spinal cord injury, and other acute or chronic neurological and neurosurgical conditions; Pharmaceutical preparations for medical use consisting of a cyclosporin or another cyclophilin inhibitor as active agent and diluents to treat stroke, traumatic brain or spinal cord injury, and other acute or chronic neurological and neurosurgical conditions; pharmaceutical preparations for skin care; Pharmaceutical preparations for suppressing tumors; Pharmaceutical preparations for the prevention of diseases of the nervous system; Pharmaceutical preparations for the prevention of diseases of the metabolic system; Pharmaceutical preparations for the prevention of disorders of the metabolic system; Pharmaceutical preparations for the prevention of disorders of the nervous system; Pharmaceutical preparations for the prevention of tumours; Pharmaceutical preparations for the treatment of cancer; Pharmaceutical preparations for the treatment of central nervous system [CNS] diseases; Pharmaceutical preparations for the treatment of diseases caused by bacteria; Pharmaceutical preparations for the treatment of diseases of the metabolic system; Pharmaceutical preparations for the treatment of disorders of the metabolic system; Pharmaceutical preparations for the treatment of kidney diseases; Pharmaceutical preparations for the treatment of kidney disorders; Pharmaceutical preparations for the treatment of Parkinson's disease; Pharmaceutical preparations for the treatment of tumours; Pharmaceutical preparations for the treatment of viral diseases; Pharmaceutical preparations for treating diabetes; Pharmaceutical preparations for treating heatstroke; Pharmaceutical preparations for treating malignant tumors; Pharmaceutical preparations for treating metabolic disorders; Pharmaceutical preparations for treating peripheral nervous system disorders; Pharmaceutical preparations for use as immunosuppressive agents; Pharmaceutical preparations for use in chemotherapy; Pharmaceutical preparations for use in oncology; Pharmaceutical preparations for use in organ transplantation; Pharmaceutical preparations for use in tissue transplantation; Pharmaceutical preparations for use within the area of neurological intensive care; Pharmaceutical preparations for veterinary use; pharmaceuticals; Pharmaceuticals, medical and veterinary preparations; phosphates for pharmaceutical purposes; phosphates for veterinary purposes; Plasters, materials for dressings; potassium salts for medical purposes; potassium salts for veterinary purposes; Preparations for destroying vermin; quinine for medical purposes; quinine for veterinary purposes; salts for medical purposes; salts for veterinary purposes; Sanitary preparations for medical purposes; sanitary preparations for veterinary purposes; slimming pills; sodium salts for medical purposes; sodium salts for veterinary purposes; sulfonamides [medicines]; tinctures for medical purposes; tinctures for veterinary purposes; tonics [medicines]; tonics for medical use; tonics for veterinary use; vaccines; vaccines for human use; veterinary preparations; Veterinary preparations and substances; Veterinary vaccines; drugs and pharmaceutical preparations for acute and chronic neurological diseases and conditions (including preventive treatment); Esters for veterinary use; esters for veterinary purposes. Apparatus and instruments for measuring, testing and analyzing biological samples, blood or other bodily fluids, not for medical purposes; chromatography apparatus for laboratory use; diagnostic apparatus, not for medical purposes; DNA chips; laboratory apparatus and instruments; quantity indicators respirometer; scientific research and laboratory apparatus, educational apparatus and simulators; electrodes for laboratory research. Apparatus for analyzing substances [for medical use]; apparatus for blood tests [for medical use]; apparatus for use in medical analysis; blood testing apparatus; blood testing equipment; electrodes for medical use; medical analytical apparatus for medical purposes; medical apparatus and instruments; medical diagnostic apparatus for medical purposes; medical diagnostic instruments; probes for medical purposes; probes for veterinary purposes; medical electrodes; electrodes for use in connection with medical apparatus; electrodes for cardiology; electrodes for veterinary use, namely medical electrodes. Analysis of human tissues for medical research; bacteriological analysism, consultation; biochemical research; biological analysis; biological laboratory services; biological research and analysis; biological research, clinical research and medical research; Biological sample analysis for scientific and medical research purposes; Biological samples, blood or other bodily fluids analysis services for scientific and medical research purposes; biotechnology research; blood analysis services; Blood analysis services for scientific and medical re-search purposes; chemical analysis and research; Chemical research and analysis ser-vices; Chemistry consultancy services; clinical research; clinical research and trials; Clinical trials; conducting clinical trials; Conducting clinical trials for others; Conducting clinical trials for pharmaceutical products; conducting early evaluations in the field of new pharmaceuticals; Consultancy in the field of cosmetics, namely, consultancy in connection with the quality inspection, research and development of cosmetic products and medicated cosmetic products; Consultancy in the field of sanitary research for medical purpose; consultancy in pharmaceutical, pharmacogenetics, medical chemistry, veterinary, for research purposes; Consultancy services in the field of biology; Consultancy services in the field of biotechnology; Consulting on pharmacogenetics; cosmetic research; Cosmetic research and analysis services; Cosmetic research services and laboratory analysis services in the field of cosmetics; Design and development of computer hardware and software; Design and development of diagnostic apparatus and instruments; Design and development of medical diagnostic apparatus and instruments; development, testing and consultancy services in the fields of biotechnology, pharmaceutical, medical, sanitary, veterinary, chemistry, biology and pharmacogenetics; DNA analysis for scientific and medical research purposes; Drug and pharmaceutical discovery, testing and development services; drug discovery services; Industrial analysis and research services; laboratory research services relating to pharmaceuticals; Medical and veterinary research and development and consultancy related there-to; medical laboratory services; medical research; pharmaceutical product evaluation; pharmaceutical products development; pharmaceutical research and development; pharmaceutical research services; providing information in connection with all the aforementioned services; Providing medical and veterinary testing services in the field of research relating to medicines, drug discovery, drug development and drug screening and consultancy related thereto; research and development in the field of biotechnology; research and development in the field of microorganisms and cells; research and development in the pharmaceutical and biotechnology fields; research and development services; research and testing; research of pharmaceuticals; research relating to biotechnology; research relating to pharmaceuticals; Research, development, and testing services, and consultancy related thereto, in the fields of biotechnology, pharmaceuticals, chemistry, biology and pharmacogenetics; Research, development, and testing services, and consultancy related thereto, in the medical, sanitary, veterinary fields; Research, development, and testing services, and consultancy related thereto, in the fields of biotechnology, pharmaceuticals, sanitary products, chemistry, biology and pharmacogenetics; Research, development, testing and consultancy services in the fields of biotechnology, pharmaceutical, medical, sanitary, veterinary, chemistry, biology and pharmacogenetics; Research, development, testing, scientific consultancy services in the fields of biotechnology, pharmaceutical, medical, sanitary, veterinary, chemistry, biology and pharmacogenetics; research, research in the field of environmental protection; Re-search, test and development of sanitary, pharmaceutical, medical, medicinal chemical, veterinary preparations; research, test and development of biotechnical, biological preparations; research, testing and development in the field of diagnostic preparations; Research, testing and development in the field of diagnostic preparations; Research, testing and development of diagnostic preparations for medical purpose; scientific analysis; Scientific and technological services and research and design relating thereto; scientific laboratory ser-vices; scientific research; scientific research relating to cosmetics; testing of pharmaceuticals; toxicity analysis; toxicity testing for research purposes; Veterinary laboratory services. Agriculture, horticulture and forestry service; Analysis of human serum for medical treatment; analysis of human tissues for medical treatment; Consultancy in the dental medicare field; consultancy in the field of cosmetics; Consultancy in the field of cosmetics, namely consultancy in connection with the selection of cosmetic products and medicated cosmetic products; Consultancy in the medical field (other than dentistry); drug screening for medical purposes; health care; health care services; Hygienic and beauty care for human beings or animals; medical and surgical diagnostic services; Medical and surgical diagnostic services; Medical consultancy in the field of pharmacogenetics; Medical consultancy services; medical diagnostic services; Medical services; Medical testing for diagnostic or treatment purposes; Pharmaceutical consultancy services; providing information in connection with all the aforementioned services; rental of ultrasonic diagnostic apparatus; therapy services; Veterinary consultancy services; Veterinary services.
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
[ Acetates for pharmaceutical purposes; acids for pharmaceutical purposes; adjuvants for medical purposes; aldehydes for pharmaceutical purposes; alginates for pharmaceutical purposes; amino acids for medical purposes; amino acids for veterinary purposes; antibiotics; antidiabetic pharmaceuticals; food supplements, namely, antioxidant pills; food supplements, namely, antioxidants; antitumor drugs in the nature of tumor suppressing agents; appetite suppressant pills; appetite suppressants; appetite suppressants for medical purposes; appetite suppressants for veterinary purposes; bacterial preparations for medical use; bacterial preparations for veterinary use; bacteriological culture mediums; bacteriological preparations for medical purposes; bacteriological preparations for medical use; bacteriological preparations for veterinary purposes; bacteriological preparations for veterinary use; biological preparations for medical purposes for the treatment of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; biological preparations for the treatment of cancer; biological tissue cultures for medical purposes; biological tissue cultures for veterinary purposes; biological tissues for implantation being implants comprising living tissue; bouillons for bacteriological cultures; cachets being capsules sold empty for pharmaceutical preparations; capsules sold empty for pharmaceutical preparations; castor oil for medical purposes; cellulose ethers for pharmaceutical purposes; chemical preparations for medical purposes, namely, for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; chemical preparations for pharmaceutical purposes, namely, for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; chemicopharmaceutical preparations for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; cytostatic drugs for medical purposes; decoctions for pharmaceutical purposes, namely, for the treatment of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; dental wax; diagnostic biomarker reagents for medical purposes; diagnostic biomarker reagents for veterinary purposes; diagnostic preparations for medical and veterinary use; diagnostic preparations for medical use; diagnostic preparations for veterinary use; diagnostic preparations for medical purposes; diagnostic preparations for veterinary purposes; diagnostic radiopharmaceutical preparations; dietary supplements for animals; dietary supplements for humans; dietetic food and substances adapted for medical or veterinary use, namely, food for human and animal babies; dietetic food and substances adapted for medical or veterinary use; dietetic substances adapted for medical use, namely, food for babies; digestive enzymes being dietary supplements; disinfectants; drugs for medical purposes in the nature of medical preparations for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; pharmaceutical preparations, namely, elixirs for the treatment of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; enzyme dietary supplements; enzyme preparations for medical purposes; enzyme preparations for veterinary purposes; enzymes for medical purposes; enzymes for veterinary purposes; esters for pharmaceutical use; ethers for pharmaceutical purposes; ferments for pharmaceutical purposes; ferments for pharmaceutical use; ferments for veterinary purposes; ferments for veterinary use; food esters for pharmaceutical purposes; formic aldehyde for pharmaceutical purposes; formic aldehyde for veterinary purposes; ] fungicides, herbicides; [ in vitro diagnostic preparations for medical use; skin lotions for medical purposes; skin lotions for pharmaceutical purposes; material for stopping teeth; material for stopping teeth, dental wax; media for bacteriological cultures; medical and veterinary preparations and products for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; medical preparations for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; medical preparations for slimming purposes; medical vaccines; medicated animal feed; medicinal drinks; medicinal infusions for treating metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; medicinal oils; medicines and pharmaceutical preparations for neurosurgical conditions, brain damage, and neurological operations; medicines and pharmaceutical preparations for neurosurgical conditions, brain damage and brain operations; medicines and pharmaceutical preparations for the treatment of neurosurgical conditions, brain damage, brain operations, and other physical and neurological ailments of the brain; medicines and pharmaceutical preparations for the treatment of neurosurgical conditions, namely, for brain damage and for use in brain operations and other physical and neurological ailments of the brain; medicines and pharmaceutical preparations for use as immunosuppressive agents; medicines and pharmaceutical preparations for use as immunosuppressive agents in organ transplants or other medical and clinical uses of immunosuppressive agents; medicines and pharmaceutical preparations for use as immunosuppressive agents for organ transplants; medicines and pharmaceutical preparations for neurological conditions within the area of neurological intensive care; medicines for human purposes in the nature of medicinal preparations for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; mixed biological preparations for medical purposes, namely, for the treatment of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; nutritional supplements; nutritional supplements for livestock feed; medicated ointments for medical purposes, namely, for treating dermatological conditions; pharmaceutical and veterinary preparations for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; pharmaceutical and veterinary preparations, namely, medicines and pharmaceutical preparations for the treatment and prevention of acute and chronic neurological illnesses and conditions; pharmaceutical and veterinary preparations, namely, medicines and pharmaceutical preparations for acute and chronic neurological illnesses and conditions and for preventative treatment; pharmaceutical drugs in the nature of pharmaceutical preparations for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; pharmaceutical preparations acting on the central nervous system; pharmaceutical preparations and other ] preparations for destroying vermin; fungicides and herbicides [ ; pharmaceutical preparations and substances for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; pharmaceutical preparations and substances for the prevention of cancer; pharmaceutical preparations and substances for the treatment of cancer; pharmaceutical preparations and substances for use in oncology; pharmaceutical preparations for activating cellular function; pharmaceutical preparations for human use for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; pharmaceutical preparations for medical purposes and veterinary purposes, namely, for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; pharmaceutical preparations for medical use consisting of a cyclosporin as active agent and diluents to treat stroke, traumatic brain or spinal cord injury, and other acute or chronic neurological and neurosurgical conditions; pharmaceutical preparations for medical use consisting of a cyclosporin or another cyclophilin inhibitor as active agent and diluents to treat stroke, traumatic brain or spinal cord injury, and other acute or chronic neurological and neurosurgical conditions; pharmaceutical preparations for skin care; pharmaceutical preparations for suppressing tumors; pharmaceutical preparations for the prevention of diseases of the nervous system; pharmaceutical preparations for the prevention of diseases of the metabolic system; pharmaceutical preparations for the prevention of disorders of the metabolic system; pharmaceutical preparations for the prevention of disorders of the nervous system; pharmaceutical preparations for the prevention of tumors; pharmaceutical preparations for the treatment of cancer; pharmaceutical preparations for the treatment of central nervous system diseases; pharmaceutical preparations for the treatment of diseases caused by bacteria in the nature of antibacterial pharmaceuticals; pharmaceutical preparations for the treatment of diseases of the metabolic system; pharmaceutical preparations for the treatment of disorders of the metabolic system; pharmaceutical preparations for the treatment of kidney diseases; pharmaceutical preparations for the treatment of kidney disorders; pharmaceutical preparations for the treatment of Parkinson's disease; pharmaceutical preparations for the treatment of tumors; pharmaceutical preparations for the treatment of viral diseases in the nature of antivirals; pharmaceutical preparations for treating diabetes; pharmaceutical preparations for treating heatstroke; pharmaceutical preparations for treating malignant tumors; pharmaceutical preparations for treating metabolic disorders; pharmaceutical preparations for treating peripheral nervous system disorders; pharmaceutical preparations for use as immunosuppressive agents; pharmaceutical preparations for use in chemotherapy; pharmaceutical preparations for use in oncology; pharmaceutical preparations for use in organ transplantation; pharmaceutical preparations for use in tissue transplantation; pharmaceutical preparations for neurological conditions within the area of neurological intensive care; pharmaceutical preparations for the prevention of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; pharmaceutical preparations for the treatment of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; medical and veterinary preparations for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; phosphates for pharmaceutical purposes; phosphates for veterinary purposes; medical plasters; medical dressings; potassium salts for medical purposes; potassium salts for veterinary purposes; preparations for destroying vermin; quinine for medical purposes; quinine for veterinary purposes; mineral salts for medical purposes; sanitary preparations for medical purposes; sanitary preparations for veterinary purposes; slimming pills being medical preparations for slimming purposes; sodium salts for medical purposes; sodium salts for veterinary purposes; sulfonamide preparations; tinctures being medicinal drinks for medical purposes; tinctures being medicinal drinks for veterinary purposes; tonics being medicinal drinks; tonics being medicinal drinks for medical use; tonics being medicinal drinks for veterinary use; vaccines; vaccines for human use; veterinary vaccines; drugs and pharmaceutical preparations for acute and chronic neurological diseases and conditions including preventive treatment; the aforementioned rare diseases consisting of Alpers Disease, ALS (Amyotrophic Lateral Sclerosis), Autism, Barth syndrome, Complex I Deficiency (NADH dehydrogenase deficiency), Complex II Deficiency (NADH-CoQ reductase deficiency), Complex III Deficiency (Ubiquinone-cytochrome c oxidoreductase deficiency), Complex IV Deficiency/COX Deficiency, Complex V Deficiency (ATP synthase deficiency), CPEO (Chronic Progressive External Ophthalmoplegia Syndrome), Friedreich's ataxia (FRDA or FA), KSS (Kearns-Sayre Syndrome), Lactic Acidosis, Leigh Disease or Syndrome (Subacute Necrotizing Encephalomyelopathy), LHON (Leber's hereditary optic neuropathy), MELAS (Mitochondrial Encephalomyopathy Lactic Acidosis and Strokelike Episodes), MERRF (Myoclonic Epilepsy and Ragged-Red Fiber Disease), MIDD (Maternally Inherited Diabetes and Deafness), Mitochondrial Myopathy, MNGIE (Myoneurogastointestinal Disorder and Encephalopathy, NARP) (Neuropathy, Ataxia, and Retinitis Pigmentosa), Neurodegenerative disorders associated with Parkinson's, Alzheimer's or Huntington's disease, Pearson Syndrome, Pyruvate Carboxylase Deficiency, Pyruvate Dehydrogenase Deficiency, POLG Mutations ] Chromatography apparatus for laboratory use; DNA chips; electrodes for laboratory research [ Blood testing apparatus; electrodes for medical use; probes for medical purposes; probes for veterinary purposes; electrodes for veterinary use, namely, medical electrodes ] [ Analysis of human tissues for medical research; bacteriological analysis and consultation relating thereto; biochemical research; biological analysis; scientific biological laboratory services; biological research and analysis; biological research, medical research and clinical research in the fields of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; biological sample analysis for scientific and medical research purposes; biological samples, blood or other bodily fluids analysis services for scientific and medical research purposes; biotechnology research; blood analysis services; blood analysis services for scientific and medical research purposes; chemical analysis and research; chemical research and analysis services; chemistry consultancy services; clinical research in the fields of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; clinical research and trials for others in the fields of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; scientific research, namely, conducting clinical trials for others; conducting clinical trials being scientific research for others; conducting clinical trials for others; conducting clinical trials for pharmaceutical products for others; conducting early evaluations in the field of new pharmaceuticals; ] consultancy in the field of cosmetics, namely, consultancy in connection with the quality inspection, research and development of cosmetic products and medicated cosmetic products; [ consultancy in the field of sanitary research for medical purpose; consultancy in pharmaceutical, pharmacogenetics, medical chemistry, and veterinary research; consultancy services in the field of biological research; consultancy services in the field of biotechnology; consulting on pharmacogenetics in the nature of pharmaceutical consultation; ] cosmetics research; cosmetics research and analysis services; cosmetics research services and laboratory analysis services in the field of cosmetics; design and development of computer hardware and software; [ design and development of diagnostic apparatus and instruments for medical use; design and development of medical diagnostic apparatus and instruments; development, testing and consultancy services in the fields of biotechnology research, pharmaceutical research, medical research, veterinary medicine research, chemistry research, biology research, and pharmacogenetics research; DNA analysis for scientific and medical research purposes; drug and pharmaceutical discovery, testing and development services; drug discovery services; industrial analysis and research services in the fields of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; laboratory research services relating to pharmaceuticals; medical and veterinary product research and development and consultancy related thereto; medical laboratory services; medical research; pharmaceutical product evaluation; pharmaceutical products development; pharmaceutical research and development; pharmaceutical research services; providing information in connection with all the aforementioned services; providing medical and veterinary testing services in the field of research relating to medicines, drug discovery, drug development and drug screening, and consultancy related thereto; research and development in the field of biotechnology; biochemical research and development of microorganisms and cells; research and development in the pharmaceutical and biotechnology fields; scientific research and development services; research and testing in the fields of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; research of pharmaceuticals; research relating to biotechnology; research relating to pharmaceuticals; research, development, and testing services, and consultancy related thereto, in the fields of biotechnology products, pharmaceutical products, sanitary products, medical products, veterinary products, chemistry products, biology products, and pharmacogenetics products; research, development, and testing services, and consultancy related thereto, in the fields of biotechnology, pharmaceuticals, sanitary products, chemistry, biology and pharmacogenetics; research, development, testing and consultancy services in the fields of biotechnology products, pharmaceutical products, medical products, sanitary products, veterinary products, chemistry products, biology products, and pharmacogenetics products; research, development, testing, scientific consultancy services in the fields of biotechnology products, pharmaceutical products, medical products, sanitary products, veterinary products, chemistry products, biology products, and pharmacogenetics products; research in the field of environmental protection; research, testing and development of sanitary, pharmaceutical, medical, medicinal chemical, veterinary preparations; research, testing and development of biotechnical, biological preparations; research, testing and development in the field of diagnostic preparations; research, testing and development of diagnostic preparations for medical purpose; scientific analysis in the fields of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; scientific and technological services, namely, scientific research, analysis and testing in the fields of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction, and research and design relating thereto; scientific laboratory services; scientific research; ] scientific research relating to cosmetics [ ; testing of pharmaceuticals; blood toxicity analysis; toxicity testing in the nature of drug screening for research purposes; veterinary laboratory services; the aforementioned rare diseases consisting of Alpers Disease, ALS (Amyotrophic Lateral Sclerosis), Autism, Barth syndrome, Complex I Deficiency (NADH dehydrogenase deficiency), Complex II Deficiency (NADH-CoQ reductase deficiency), Complex III Deficiency (Ubiquinone-cytochrome c oxidoreductase deficiency), Complex IV Deficiency/COX Deficiency, Complex V Deficiency (ATP synthase deficiency), CPEO (Chronic Progressive External Ophthalmoplegia Syndrome), Friedreich's ataxia (FRDA or FA), KSS (Kearns-Sayre Syndrome), Lactic Acidosis, Leigh Disease or Syndrome (Subacute Necrotizing Encephalomyelopathy), LHON (Leber's hereditary optic neuropathy), MELAS (Mitochondrial Encephalomyopathy Lactic Acidosis and Strokelike Episodes), MERRF (Myoclonic Epilepsy and Ragged-Red Fiber Disease), MIDD (Maternally Inherited Diabetes and Deafness), Mitochondrial Myopathy, MNGIE (Myoneurogastointestinal Disorder and Encephalopathy, NARP) (Neuropathy, Ataxia, and Retinitis Pigmentosa), Neurodegenerative disorders associated with Parkinson's, Alzheimer's or Huntington's disease, Pearson Syndrome, Pyruvate Carboxylase Deficiency, Pyruvate Dehydrogenase Deficiency, POLG Mutations ] [ Analysis of human serum for medical treatment; analysis of human tissues for medical treatment; ] consultancy in the field of cosmetics, namely, consultancy in connection with the selection of cosmetic products and medicated cosmetic products; [ consultancy in the medical field, other than dentistry; drug screening for medical purposes; health care; health care services; ] hygienic and beauty care for human beings or animals; [ medical and surgical diagnostic testing services; medical consultancy in the field of pharmacogenetics; medical consultancy services; medical diagnostic services in the nature of performing diagnosis of diseases; medical services; medical testing for diagnostic or treatment purposes; pharmaceutical consultancy services; ] providing information in connection with all the aforementioned services; rental of ultrasonic diagnostic apparatus [ ; veterinary consultancy services; veterinary services ]
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
esters for foodstuffs, not for pharmaceutical purposes. Fungicides, herbicides; other preparations for destroying vermin, fungicides, herbicides. Apparatus and instruments for measuring, testing and analyzing biological samples, blood or other bodily fluids, not for medical purposes; chromatography apparatus for laboratory use; diagnostic apparatus, not for medical purposes; DNA chips; laboratory apparatus and instruments; quantity indicators respirometer; scientific research and laboratory apparatus, educational apparatus and simulators; electrodes for laboratory research. Consultancy in the field of cosmetics, namely, consultancy in connection with the quality inspection, research and development of cosmetic products and medicated cosmetic products; Cosmetic research and analysis services; Cosmetic research services and laboratory analysis services in the field of cosmetics; Design and development of computer hardware and software; scientific research relating to cosmetics. Agriculture, horticulture and forestry service; consultancy in the field of cosmetics; Consultancy in the field of cosmetics, namely consultancy in connection with the selection of cosmetic products and medicated cosmetic products; Hygienic and beauty care for human beings or animals; providing information in connection with all the aforementioned services; rental of ultrasonic diagnostic apparatus; therapy services.
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
[ Acetates for pharmaceutical purposes; acids for pharmaceutical purposes; adjuvants for medical purposes; aldehydes for pharmaceutical purposes; alginates for pharmaceutical purposes; amino acids for medical purposes; amino acids for veterinary purposes; antibiotics; antidiabetic pharmaceuticals; food supplements, namely, antioxidant pills; food supplements, namely, antioxidants; antitumor drugs in the nature of tumor suppressing agents; appetite suppressant pills; appetite suppressants; appetite suppressants for medical purposes; appetite suppressants for veterinary purposes; bacterial preparations for medical use; bacterial preparations for veterinary use; bacteriological culture mediums; bacteriological preparations for medical purposes; bacteriological preparations for medical use; bacteriological preparations for veterinary purposes; bacteriological preparations for veterinary use; biological preparations for medical purposes for the treatment of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; biological preparations for the treatment of cancer; biological tissue cultures for medical purposes; biological tissue cultures for veterinary purposes; biological tissues for implantation being implants comprising living tissue; bouillons for bacteriological cultures; cachets being capsules sold empty for pharmaceutical preparations; capsules sold empty for pharmaceutical preparations; castor oil for medical purposes; cellulose ethers for pharmaceutical purposes; chemical preparations for medical purposes, namely, for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; chemical preparations for pharmaceutical purposes, namely, for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; chemicopharmaceutical preparations for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; cytostatic drugs for medical purposes; decoctions for pharmaceutical purposes, namely, for the treatment of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; dental wax; diagnostic biomarker reagents for medical purposes; diagnostic biomarker reagents for veterinary purposes; diagnostic preparations for medical and veterinary use; diagnostic preparations for medical use; diagnostic preparations for veterinary use; diagnostic preparations for medical purposes; diagnostic preparations for veterinary purposes; diagnostic radiopharmaceutical preparations; dietary supplements for animals; dietary supplements for humans; dietetic food and substances adapted for medical or veterinary use, namely, food for human and animal babies; dietetic food and substances adapted for medical or veterinary use; dietetic substances adapted for medical use, namely, food for babies; digestive enzymes being dietary supplements; disinfectants; drugs for medical purposes in the nature of medical preparations for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; pharmaceutical preparations, namely, elixirs for the treatment of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; enzyme dietary supplements; enzyme preparations for medical purposes; enzyme preparations for veterinary purposes; enzymes for medical purposes; enzymes for veterinary purposes; esters for pharmaceutical use; ethers for pharmaceutical purposes; ferments for pharmaceutical purposes; ferments for pharmaceutical use; ferments for veterinary purposes; ferments for veterinary use; food esters for pharmaceutical purposes; formic aldehyde for pharmaceutical purposes; formic aldehyde for veterinary purposes; ] fungicides, herbicides; [ in vitro diagnostic preparations for medical use; skin lotions for medical purposes; skin lotions for pharmaceutical purposes; material for stopping teeth; material for stopping teeth, dental wax; media for bacteriological cultures; medical and veterinary preparations and products for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; medical preparations for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; medical preparations for slimming purposes; medical vaccines; medicated animal feed; medicinal drinks; medicinal infusions for treating metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; medicinal oils; medicines and pharmaceutical preparations for neurosurgical conditions, brain damage, and neurological operations; medicines and pharmaceutical preparations for neurosurgical conditions, brain damage and brain operations; medicines and pharmaceutical preparations for the treatment of neurosurgical conditions, brain damage, brain operations, and other physical and neurological ailments of the brain; medicines and pharmaceutical preparations for the treatment of neurosurgical conditions, namely, for brain damage and for use in brain operations and other physical and neurological ailments of the brain; medicines and pharmaceutical preparations for use as immunosuppressive agents; medicines and pharmaceutical preparations for use as immunosuppressive agents in organ transplants or other medical and clinical uses of immunosuppressive agents; medicines and pharmaceutical preparations for use as immunosuppressive agents for organ transplants; medicines and pharmaceutical preparations for neurological conditions within the area of neurological intensive care; medicines for human purposes in the nature of medicinal preparations for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; mixed biological preparations for medical purposes, namely, for the treatment of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; nutritional supplements; nutritional supplements for livestock feed; medicated ointments for medical purposes, namely, for treating dermatological conditions; pharmaceutical and veterinary preparations for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; pharmaceutical and veterinary preparations, namely, medicines and pharmaceutical preparations for the treatment and prevention of acute and chronic neurological illnesses and conditions; pharmaceutical and veterinary preparations, namely, medicines and pharmaceutical preparations for acute and chronic neurological illnesses and conditions and for preventative treatment; pharmaceutical drugs in the nature of pharmaceutical preparations for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; pharmaceutical preparations acting on the central nervous system; pharmaceutical preparations and ] other preparations for destroying vermin; fungicides and herbicides [ ; pharmaceutical preparations and substances for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; pharmaceutical preparations and substances for the prevention of cancer; pharmaceutical preparations and substances for the treatment of cancer; pharmaceutical preparations and substances for use in oncology; pharmaceutical preparations for activating cellular function; pharmaceutical preparations for human use for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; pharmaceutical preparations for medical purposes and veterinary purposes, namely, for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; pharmaceutical preparations for medical use consisting of a cyclosporin as active agent and diluents to treat stroke, traumatic brain or spinal cord injury, and other acute or chronic neurological and neurosurgical conditions; pharmaceutical preparations for medical use consisting of a cyclosporin or another cyclophilin inhibitor as active agent and diluents to treat stroke, traumatic brain or spinal cord injury, and other acute or chronic neurological and neurosurgical conditions; pharmaceutical preparations for skin care; pharmaceutical preparations for suppressing tumors; pharmaceutical preparations for the prevention of diseases of the nervous system; pharmaceutical preparations for the prevention of diseases of the metabolic system; pharmaceutical preparations for the prevention of disorders of the metabolic system; pharmaceutical preparations for the prevention of disorders of the nervous system; pharmaceutical preparations for the prevention of tumors; pharmaceutical preparations for the treatment of cancer; pharmaceutical preparations for the treatment of central nervous system diseases; pharmaceutical preparations for the treatment of diseases caused by bacteria in the nature of antibacterial pharmaceuticals; pharmaceutical preparations for the treatment of diseases of the metabolic system; pharmaceutical preparations for the treatment of disorders of the metabolic system; pharmaceutical preparations for the treatment of kidney diseases; pharmaceutical preparations for the treatment of kidney disorders; pharmaceutical preparations for the treatment of Parkinson's disease; pharmaceutical preparations for the treatment of tumors; pharmaceutical preparations for the treatment of viral diseases in the nature of antivirals; pharmaceutical preparations for treating diabetes; pharmaceutical preparations for treating heatstroke; pharmaceutical preparations for treating malignant tumors; pharmaceutical preparations for treating metabolic disorders; pharmaceutical preparations for treating peripheral nervous system disorders; pharmaceutical preparations for use as immunosuppressive agents; pharmaceutical preparations for use in chemotherapy; pharmaceutical preparations for use in oncology; pharmaceutical preparations for use in organ transplantation; pharmaceutical preparations for use in tissue transplantation; pharmaceutical preparations for neurological conditions within the area of neurological intensive care; pharmaceutical preparations for the prevention of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; pharmaceutical preparations for the treatment of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; medical and veterinary preparations for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; phosphates for pharmaceutical purposes; phosphates for veterinary purposes; medical plasters; medical dressings; potassium salts for medical purposes; potassium salts for veterinary purposes; preparations for destroying vermin; quinine for medical purposes; quinine for veterinary purposes; mineral salts for medical purposes; sanitary preparations for medical purposes; sanitary preparations for veterinary purposes; slimming pills being medical preparations for slimming purposes; sodium salts for medical purposes; sodium salts for veterinary purposes; sulfonamide preparations; tinctures being medicinal drinks for medical purposes; tinctures being medicinal drinks for veterinary purposes; tonics being medicinal drinks; tonics being medicinal drinks for medical use; tonics being medicinal drinks for veterinary use; vaccines; vaccines for human use; veterinary vaccines; drugs and pharmaceutical preparations for acute and chronic neurological diseases and conditions including preventive treatment; the aforementioned rare diseases consisting of Alpers Disease, ALS (Amyotrophic Lateral Sclerosis), Autism, Barth syndrome, Complex I Deficiency (NADH dehydrogenase deficiency), Complex II Deficiency (NADH-CoQ reductase deficiency), Complex III Deficiency (Ubiquinone-cytochrome c oxidoreductase deficiency), Complex IV Deficiency/COX Deficiency, Complex V Deficiency (ATP synthase deficiency), CPEO (Chronic Progressive External Ophthalmoplegia Syndrome), Friedreich's ataxia (FRDA or FA), KSS (Kearns-Sayre Syndrome), Lactic Acidosis, Leigh Disease or Syndrome (Subacute Necrotizing Encephalomyelopathy), LHON (Leber's hereditary optic neuropathy), MELAS (Mitochondrial Encephalomyopathy Lactic Acidosis and Strokelike Episodes), MERRF (Myoclonic Epilepsy and Ragged-Red Fiber Disease), MIDD (Maternally Inherited Diabetes and Deafness), Mitochondrial Myopathy, MNGIE (Myoneurogastointestinal Disorder ) and Encephalopathy, NARP (Neuropathy, Ataxia, and Retinitis Pigmentosa), Neurodegenerative disorders associated with Parkinson's, Alzheimer's or Huntington's disease, Pearson Syndrome, Pyruvate Carboxylase Deficiency, Pyruvate Dehydrogenase Deficiency, POLG Mutations ] Chromatography apparatus for laboratory use; DNA chips; electrodes for laboratory research [ Blood testing apparatus; electrodes for medical use; probes for medical purposes; probes for veterinary purposes; electrodes for veterinary use, namely, medical electrodes ] [ Analysis of human tissues for medical research; bacteriological analysis and consultation relating thereto; biochemical research; biological analysis; scientific biological laboratory services; biological research and analysis; biological research, medical research and clinical research in the fields of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; biological sample analysis for scientific and medical research purposes; biological samples, blood or other bodily fluids analysis services for scientific and medical research purposes; biotechnology research; blood analysis services; blood analysis services for scientific and medical research purposes; chemical analysis and research; chemical research and analysis services; chemistry consultancy services; clinical research in the fields of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; clinical research and trials for others in the fields of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; scientific research, namely, conducting clinical trials for others; conducting clinical trials being scientific research for others; conducting clinical trials for others; conducting clinical trials for pharmaceutical products for others; conducting early evaluations in the field of new pharmaceuticals; ] consultancy in the field of cosmetics, namely, consultancy in connection with the quality inspection, research and development of cosmetic products and medicated cosmetic products [ ; consultancy in the field of sanitary research for medical purpose; consultancy in pharmaceutical, pharmacogenetics, medical chemistry, and veterinary research; consultancy services in the field of biological research; consultancy services in the field of biotechnology; consulting on pharmacogenetics in the nature of pharmaceutical consultation; cosmetics research; cosmetics research and analysis services; cosmetics research services and laboratory analysis services in the field of cosmetics; design and development of computer hardware and software; design and development of diagnostic apparatus and instruments for medical use; design and development of medical diagnostic apparatus and instruments; development, testing and consultancy services in the fields of biotechnology research, pharmaceutical research, medical research, veterinary medicine research, chemistry research, biology research, and pharmacogenetics research; DNA analysis for scientific and medical research purposes; drug and pharmaceutical discovery, testing and development services; drug discovery services; industrial analysis and research services in the fields of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; laboratory research services relating to pharmaceuticals; medical and veterinary product research and development and consultancy related thereto; medical laboratory services; medical research; pharmaceutical product evaluation; pharmaceutical products development; pharmaceutical research and development; pharmaceutical research services; providing information in connection with all the aforementioned services; providing medical and veterinary testing services in the field of research relating to medicines, drug discovery, drug development and drug screening, and consultancy related thereto; research and development in the field of biotechnology; biochemical research and development of microorganisms and cells; research and development in the pharmaceutical and biotechnology fields; scientific research and development services; research and testing in the fields of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; research of pharmaceuticals; research relating to biotechnology; research relating to pharmaceuticals; research, development, and testing services, and consultancy related thereto, in the fields of biotechnology products, pharmaceutical products, sanitary products, medical products, veterinary products, chemistry products, biology products, and pharmacogenetics products; research, development, and testing services, and consultancy related thereto, in the fields of biotechnology, pharmaceuticals, sanitary products, chemistry, biology and pharmacogenetics; research, development, testing and consultancy services in the fields of biotechnology products, pharmaceutical products, medical products, sanitary products, veterinary products, chemistry products, biology products, and pharmacogenetics products; research, development, testing, scientific consultancy services in the fields of biotechnology products, pharmaceutical products, medical products, sanitary products, veterinary products, chemistry products, biology products, and pharmacogenetics products; research in the field of environmental protection; research, testing and development of sanitary, pharmaceutical, medical, medicinal chemical, veterinary preparations; research, testing and development of biotechnical, biological preparations; research, testing and development in the field of diagnostic preparations; research, testing and development of diagnostic preparations for medical purpose; scientific analysis in the fields of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction; scientific and technological services, namely, scientific research, analysis and testing in the fields of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, mitochondrial diseases, and rare diseases involving mitochondrial and/or metabolic dysfunction, and research and design relating thereto; scientific laboratory services; scientific research; scientific research relating to cosmetics; testing of pharmaceuticals; blood toxicity analysis; toxicity testing in the nature of drug screening for research purposes; veterinary laboratory services; the aforementioned rare diseases consisting of Alpers Disease, ALS (Amyotrophic Lateral Sclerosis), Autism, Barth syndrome, Complex I Deficiency (NADH dehydrogenase deficiency), Complex II Deficiency (NADH-CoQ reductase deficiency), Complex III Deficiency (Ubiquinone-cytochrome c oxidoreductase deficiency), Complex IV Deficiency/COX Deficiency, Complex V Deficiency (ATP synthase deficiency), CPEO (Chronic Progressive External Ophthalmoplegia Syndrome), Friedreich's ataxia (FRDA or FA), KSS (Kearns-Sayre Syndrome), Lactic Acidosis, Leigh Disease or Syndrome (Subacute Necrotizing Encephalomyelopathy), LHON (Leber's hereditary optic neuropathy), MELAS (Mitochondrial Encephalomyopathy Lactic Acidosis and Strokelike Episodes), MERRF (Myoclonic Epilepsy and Ragged-Red Fiber Disease), MIDD (Maternally Inherited Diabetes and Deafness), Mitochondrial Myopathy, MNGIE (Myoneurogastointestinal Disorder ) and Encephalopathy, NARP (Neuropathy, Ataxia, and Retinitis Pigmentosa), Neurodegenerative disorders associated with Parkinson's, Alzheimer's or Huntington's disease, Pearson Syndrome, Pyruvate Carboxylase Deficiency, Pyruvate Dehydrogenase Deficiency, POLG Mutations ] [ -Analysis of human serum for medical treatment; analysis of human tissues for medical treatment; ] consultancy in the field of cosmetics, namely, consultancy in connection with the selection of cosmetic products and medicated cosmetic products; [ consultancy in the medical field, other than dentistry; drug screening for medical purposes; health care; health care services; ] hygienic and beauty care for human beings or animals; [ medical and surgical diagnostic testing services; medical consultancy in the field of pharmacogenetics; medical consultancy services; medical diagnostic services in the nature of performing diagnosis of diseases; medical services; medical testing for diagnostic or treatment purposes; pharmaceutical consultancy services; ] providing information in connection with all the aforementioned services; rental of ultrasonic diagnostic apparatus [ ; veterinary consultancy services; veterinary services ]
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Acetates for pharmaceutical purposes; acids for pharmaceutical purposes; adjuvants for medical purposes; aldehydes for pharmaceutical purposes; alginates for pharmaceutical purposes; amino acids for medical purposes; amino acids for veterinary purposes; antibiotics; antidiabetic pharmaceuticals; food supplements, namely, antioxidant pills; food supplements, namely, antioxidants; antitumor drugs in the nature of tumor suppressing agents; appetite suppressant pills; appetite suppressants; appetite suppressants for medical purposes; appetite suppressants for veterinary purposes; bacterial preparations for medical use; bacterial preparations for veterinary use; bacteriological culture mediums; bacteriological preparations for medical purposes; bacteriological preparations for medical use; bacteriological preparations for veterinary purposes; bacteriological preparations for veterinary use; biological preparations for medical purposes for the treatment of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; biological preparations for the treatment of cancer; biological tissue cultures for medical purposes; biological tissue cultures for veterinary purposes; biological tissues for implantation being implants comprising living tissue; bouillons for bacteriological cultures; cachets being capsules sold empty for pharmaceutical preparations; capsules sold empty for pharmaceutical preparations; castor oil for medical purposes; cellulose ethers for pharmaceutical purposes; chemical preparations for medical purposes, namely, for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; chemical preparations for pharmaceutical purposes, namely, for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; chemicopharmaceutical preparations for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; cytostatic drugs for medical purposes; decoctions for pharmaceutical purposes, namely, for the treatment of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; dental wax; diagnostic biomarker reagents for medical purposes; diagnostic biomarker reagents for veterinary purposes; diagnostic preparations for medical and veterinary use; diagnostic preparations for medical use; diagnostic preparations for veterinary use; diagnostic preparations for medical purposes; diagnostic preparations for veterinary purposes; diagnostic radiopharmaceutical preparations; dietary supplements for animals; dietary supplements for humans; dietetic food and substances adapted for medical or veterinary use, namely, food for human and animal babies; dietetic food and substances adapted for medical or veterinary use; dietetic substances adapted for medical use, namely, food for babies; digestive enzymes being dietary supplements; disinfectants; drugs for medical purposes in the nature of medical preparations for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; pharmaceutical preparations, namely, elixirs for the treatment of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; enzyme dietary supplements; enzyme preparations for medical purposes; enzyme preparations for veterinary purposes; enzymes for medical purposes; enzymes for veterinary purposes; esters for pharmaceutical use; ethers for pharmaceutical purposes; ferments for pharmaceutical purposes; ferments for pharmaceutical use; ferments for veterinary purposes; ferments for veterinary use; food esters for pharmaceutical purposes; formic aldehyde for pharmaceutical purposes; formic aldehyde for veterinary purposes; fungicides, herbicides; in vitro diagnostic preparations for medical use; skin lotions for medical purposes; skin lotions for pharmaceutical purposes; material for stopping teeth; material for stopping teeth, dental wax; media for bacteriological cultures; medical and veterinary preparations and products for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; medical preparations for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; medical preparations for slimming purposes; medical vaccines; medicated animal feed; medicinal drinks; medicinal infusions for treating metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; medicinal oils; medicines and pharmaceutical preparations for neurosurgical conditions, brain damage, and neurological operations; medicines and pharmaceutical preparations for neurosurgical conditions, brain damage and brain operations; medicines and pharmaceutical preparations for the treatment of neurosurgical conditions, brain damage, brain operations, and other physical and neurological ailments of the brain; medicines and pharmaceutical preparations for the treatment of neurosurgical conditions, namely, for brain damage and for use in brain operations and other physical and neurological ailments of the brain; medicines and pharmaceutical preparations for use as immunosuppressive agents; medicines and pharmaceutical preparations for use as immunosuppressive agents in organ transplants or other medical and clinical uses of immunosuppressive agents; medicines and pharmaceutical preparations for use as immunosuppressive agents for organ transplants; medicines and pharmaceutical preparations for neurological conditions within the area of neurological intensive care; medicines for human purposes in the nature of medicinal preparations for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; mixed biological preparations for medical purposes, namely, for the treatment of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; nutritional supplements; nutritional supplements for livestock feed; medicated ointments for medical purposes, namely, for treating dermatological conditions; pharmaceutical and veterinary preparations for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; pharmaceutical and veterinary preparations, namely, medicines and pharmaceutical preparations for the treatment and prevention of acute and chronic neurological illnesses and conditions; pharmaceutical and veterinary preparations, namely, medicines and pharmaceutical preparations for acute and chronic neurological illnesses and conditions and for preventative treatment; pharmaceutical drugs in the nature of pharmaceutical preparations for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; pharmaceutical preparations acting on the central nervous system; pharmaceutical preparations and other preparations for destroying vermin; fungicides and herbicides; pharmaceutical preparations and substances for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; pharmaceutical preparations and substances for the prevention of cancer; pharmaceutical preparations and substances for the treatment of cancer; pharmaceutical preparations and substances for use in oncology; pharmaceutical preparations for activating cellular function; pharmaceutical preparations for human use for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; pharmaceutical preparations for medical purposes and veterinary purposes, namely, for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; pharmaceutical preparations for medical use consisting of a cyclosporin as active agent and diluents to treat stroke, traumatic brain or spinal cord injury, and other acute or chronic neurological and neurosurgical conditions; pharmaceutical preparations for medical use consisting of a cyclosporin or another cyclophilin inhibitor as active agent and diluents to treat stroke, traumatic brain or spinal cord injury, and other acute or chronic neurological and neurosurgical conditions; pharmaceutical preparations for skin care; pharmaceutical preparations for suppressing tumors; pharmaceutical preparations for the prevention of diseases of the nervous system; pharmaceutical preparations for the prevention of diseases of the metabolic system; pharmaceutical preparations for the prevention of disorders of the metabolic system; pharmaceutical preparations for the prevention of disorders of the nervous system; pharmaceutical preparations for the prevention of tumors; pharmaceutical preparations for the treatment of cancer; pharmaceutical preparations for the treatment of central nervous system diseases; pharmaceutical preparations for the treatment of diseases caused by bacteria in the nature of antibacterial pharmaceuticals; pharmaceutical preparations for the treatment of diseases of the metabolic system; pharmaceutical preparations for the treatment of disorders of the metabolic system; pharmaceutical preparations for the treatment of kidney diseases; pharmaceutical preparations for the treatment of kidney disorders; pharmaceutical preparations for the treatment of Parkinson's disease; pharmaceutical preparations for the treatment of tumors; pharmaceutical preparations for the treatment of viral diseases in the nature of antivirals; pharmaceutical preparations for treating diabetes; pharmaceutical preparations for treating heatstroke; pharmaceutical preparations for treating malignant tumors; pharmaceutical preparations for treating metabolic disorders; pharmaceutical preparations for treating peripheral nervous system disorders; pharmaceutical preparations for use as immunosuppressive agents; pharmaceutical preparations for use in chemotherapy; pharmaceutical preparations for use in oncology; pharmaceutical preparations for use in organ transplantation; pharmaceutical preparations for use in tissue transplantation; pharmaceutical preparations for neurological conditions within the area of neurological intensive care; pharmaceutical preparations for the prevention of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; pharmaceutical preparations for the treatment of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; medical and veterinary preparations for metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; phosphates for pharmaceutical purposes; phosphates for veterinary purposes; medical plasters; medical dressings; potassium salts for medical purposes; potassium salts for veterinary purposes; preparations for destroying vermin; quinine for medical purposes; quinine for veterinary purposes; mineral salts for medical purposes; sanitary preparations for medical purposes; sanitary preparations for veterinary purposes; slimming pills being medical preparations for slimming purposes; sodium salts for medical purposes; sodium salts for veterinary purposes; sulfonamide preparations; tinctures being medicinal drinks for medical purposes; tinctures being medicinal drinks for veterinary purposes; tonics being medicinal drinks; tonics being medicinal drinks for medical use; tonics being medicinal drinks for veterinary use; vaccines; vaccines for human use; veterinary vaccines; drugs and pharmaceutical preparations for acute and chronic neurological diseases and conditions including preventive treatment; diagnostic agents, preparations and substances for medical purposes Chromatography apparatus for laboratory use; DNA chips; electrodes for laboratory research Blood testing apparatus; electrodes for medical use; probes for medical purposes; probes for veterinary purposes; electrodes for veterinary use, namely, medical electrodes Analysis of human tissues for medical research; bacteriological analysis and consultation relating thereto; biochemical research; biological analysis; scientific biological laboratory services; biological research and analysis; biological research, medical research and clinical research in the fields of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; biological sample analysis for scientific and medical research purposes; biological samples, blood or other bodily fluids analysis services for scientific and medical research purposes; biotechnology research; blood analysis services; blood analysis services for scientific and medical research purposes; chemical analysis and research; chemical research and analysis services; chemistry consultancy services; clinical research in the fields of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; clinical research and trials for others in the fields of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; scientific research, namely, conducting clinical trials for others; conducting clinical trials being scientific research for others; conducting clinical trials for others; conducting clinical trials for pharmaceutical products for others; conducting early evaluations in the field of new pharmaceuticals; consultancy in the field of cosmetics, namely, consultancy in connection with the quality inspection, research and development of cosmetic products and medicated cosmetic products; consultancy in the field of sanitary research for medical purpose; consultancy in pharmaceutical, pharmacogenetics, medical chemistry, and veterinary research; consultancy services in the field of biological research; consultancy services in the field of biotechnology; consulting on pharmacogenetics in the nature of pharmaceutical consultation; cosmetics research; cosmetics research and analysis services; cosmetics research services and laboratory analysis services in the field of cosmetics; design and development of computer hardware and software; design and development of diagnostic apparatus and instruments for medical use; design and development of medical diagnostic apparatus and instruments; development, testing and consultancy services in the fields of biotechnology research, pharmaceutical research, medical research, veterinary medicine research, chemistry research, biology research, and pharmacogenetics research; DNA analysis for scientific and medical research purposes; drug and pharmaceutical discovery, testing and development services; drug discovery services; industrial analysis and research services in the fields of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; laboratory research services relating to pharmaceuticals; medical and veterinary product research and development and consultancy related thereto; medical laboratory services; medical research; pharmaceutical product evaluation; pharmaceutical products development; pharmaceutical research and development; pharmaceutical research services; providing information in connection with all the aforementioned services; providing medical and veterinary testing services in the field of research relating to medicines, drug discovery, drug development and drug screening, and consultancy related thereto; research and development in the field of biotechnology; biochemical research and development of microorganisms and cells; research and development in the pharmaceutical and biotechnology fields; scientific research and development services; research and testing in the fields of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; research of pharmaceuticals; research relating to biotechnology; research relating to pharmaceuticals; research, development, and testing services, and consultancy related thereto, in the fields of biotechnology products, pharmaceutical products, sanitary products, medical products, veterinary products, chemistry products, biology products, and pharmacogenetics products; research, development, and testing services, and consultancy related thereto, in the fields of biotechnology, pharmaceuticals, sanitary products, chemistry, biology and pharmacogenetics; research, development, testing and consultancy services in the fields of biotechnology products, pharmaceutical products, medical products, sanitary products, veterinary products, chemistry products, biology products, and pharmacogenetics products; research, development, testing, scientific consultancy services in the fields of biotechnology products, pharmaceutical products, medical products, sanitary products, veterinary products, chemistry products, biology products, and pharmacogenetics products; research in the field of environmental protection; research, testing and development of sanitary, pharmaceutical, medical, medicinal chemical, veterinary preparations; research, testing and development of biotechnical, biological preparations; research, testing and development in the field of diagnostic preparations; research, testing and development of diagnostic preparations for medical purpose; scientific analysis in the fields of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases; scientific and technological services, namely, scientific research, analysis and testing in the fields of metabolic, neurological, cardiovascular and musculoskeletal diseases, cancer, diabetes, NASH, mitochondrial diseases and rare diseases, and research and design relating thereto; scientific laboratory services; scientific research; scientific research relating to cosmetics; testing of pharmaceuticals; blood toxicity analysis; toxicity testing in the nature of drug screening for research purposes; veterinary laboratory services Analysis of human serum for medical treatment; analysis of human tissues for medical treatment; consultancy in the field of cosmetics, namely, consultancy in connection with the selection of cosmetic products and medicated cosmetic products; consultancy in the medical field, namely, pharmacogenetics; consultancy in the medical field, other than dentistry; drug screening for medical purposes; health care; health care services; hygienic and beauty care for human beings or animals; medical and surgical diagnostic testing services; medical consultancy in the field of pharmacogenetics; medical consultancy services; medical diagnostic services in the nature of performing diagnosis of diseases; medical services; medical testing for diagnostic or treatment purposes; pharmaceutical consultancy services; providing information in connection with all the aforementioned services; rental of ultrasonic diagnostic apparatus; veterinary consultancy services; veterinary services
The present invention provides novel cell-permeable succinates and cell permeable precursors of succinateaimed at increasing ATP-production in mitochondria. The main part of ATP produced and utilized in the eukaryotic cell originates from mitochondrial oxidative phosphorylation, a process to which high-energy electrons are provided by the Kreb's cycle. Not all Kreb's cycle intermediates are readily permeable to the cellular membrane, one of them being succinate. The provision of the novel cell permeable succinates is envisaged to allow passage over the cellular membrane and thus the cell permeable succinates can be used to enhance mitochondrial ATP-output.
A61K 31/265 - Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
C07C 327/28 - Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
C07C 327/34 - Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups with amino groups bound to the same hydrocarbon radicals
C07C 327/32 - Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
C07C 327/30 - Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms, not being part of nitro or nitroso groups
A61K 31/22 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
C07D 211/76 - Oxygen atoms attached in position 2 or 6
A61P 11/00 - Drugs for disorders of the respiratory system
A61P 9/00 - Drugs for disorders of the cardiovascular system
A61P 21/00 - Drugs for disorders of the muscular or neuromuscular system
27.
Succinate prodrugs for use in the treatment of lactic acidosis or drug-induced side-effects due to Complex I-related impairment of mitochondrial oxidative phosphorylation
The present invention provides novel cell-permeable succinates and cell permeable precursors of succinate aimed at increasing ATP-production in mitochondria of the following formula: The main part of ATP produced and utilized in the eukaryotic cell originates from mitochondrial oxidative phosphorylation, a process to which high-energy electrons are provided by the Kreb's cycle. Not all Kreb's cycle intermediates are readily permeable to the cellular membrane, one of them being succinate. The provision of the novel cell permeable succinates is envisaged to allow passage over the cellular membrane and thus the cell permeable succinates can be used to enhance mitochondria! ATP-output.
C07C 327/30 - Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms, not being part of nitro or nitroso groups
A61K 31/265 - Esters, e.g. nitroglycerine, selenocyanates of carbonic, thiocarbonic or thiocarboxylic acids, e.g. thioacetic acid, xanthogenic acid, trithiocarbonic acid
A61K 31/351 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
A01N 43/26 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atom with two or more hetero atoms five-membered rings
A61K 31/335 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
C07C 69/34 - Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
C07C 69/52 - Esters of acyclic unsaturated carboxylic acids having the esterified carboxyl group bound to an acyclic carbon atom
C07D 323/00 - Heterocyclic compounds containing more than two oxygen atoms as the only ring hetero atoms
C07C 235/06 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations for medical use consisting of a
cyclosporin or another cyclophilin inhibitor as active agent
and diluents to treat stroke, traumatic brain or spinal cord
injury, and other acute or chronic neurological and
neurosurgical conditions.
There is provided inter alia a pharmaceutical dosage form for oral administration comprising a sanglifehrin as active ingredient in which the sanglifehrin active ingredient is protected from acid degradation in the stomach environment following oral administration.
A61K 47/44 - Oils, fats or waxes according to two or more groups of Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
The present invention relates to a cyclosporine emulsion containing: i) a cyclosporine ii) a natural oil (long chain triglyceride) iii) a phosphatidylcholine, iv) glycerol, v) a pharmaceutically tolerable alkali salt of a free fatty acid, vi) a medium chain triglyceride-oil vii) optionally, hydrochloric acid or sodium hydroxide for pH adjustment viii) water.
A61K 47/44 - Oils, fats or waxes according to two or more groups of Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
C07K 7/64 - Cyclic peptides containing only normal peptide links
A61K 47/12 - Carboxylic acidsSalts or anhydrides thereof
A61K 47/14 - Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
C07D 413/12 - Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
C12P 17/18 - Preparation of heterocyclic carbon compounds with only O, N, S, Se, or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
38.
SANGLIFEHRIN DERIVATIVES AND METHODS FOR THEIR PRODUCTION
C12P 17/18 - Preparation of heterocyclic carbon compounds with only O, N, S, Se, or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
The present invention relates to a cyclosporine emulsion containing: i) a cyclosporine ii) a natural oil (long chain triglyceride) iii) a phosphatidylcholine, iv) glycerol, v) a pharmaceutically tolerable alkali salt of a free fatty acid, vi) a medium chain triglyceride-oil vii) optionally, hydrochloric acid or sodium hydroxide for pH adjustment viii) water.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations for medical use consisting of a cyclosporin as active agent and diluents to treat stroke, traumatic brain or spinal cord injury, and other acute or chronic neurological and neurosurgical conditions
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical and veterinary preparations; including
medicines and pharmaceutical preparations for acute and
chronic neurological illnesses and conditions (including
preventive treatment); medicines and pharmaceutical
preparations for the treatment of neurosurgical conditions,
brain damage, brain operations and other physical and
neurological ailments of the brain; medicines and
pharmaceutical preparations for use within the area of
neurological intensive care; medicines and pharmaceutical
preparations for use as immunosuppressive agents (e.g for
organ transplant or other medical (and clinical) uses of
immunosuppressive agents or preparations).
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical and veterinary preparations; sanitary
preparations for medical purposes; dietetic substances
adapted for medical use, food for babies; plasters,
materials for dressings; material for stopping teeth; dental
wax; disinfectants; including medicines and pharmaceutical
preparations for acute and chronic neurological illnesses
and conditions (including preventive treatment); medicines
and pharmaceutical preparations for neurosurgical
conditions, brain damage, operations and similar; medicines
and pharmaceutical preparations for use within the area of
neurological intensive care; medicines and pharmaceutical
preparations for use as immunosuppressive agents (e.g. organ
transplant or other uses of immunosuppressive agents).
