UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Kang, Sungho
Jang, Seokjun
Han, Donghyun
Abstract
A semiconductor integrated circuit may include: a first die including a plurality of first through-silicon vias (TSVs), wherein the plurality of first TSVs are divided into TSV repair units, and the TSV repair units include first normal TSVs (NTSVs) for signal transfer and a first redundant TSV (RTSV) for replacing a first failed NTSV from among the first NTSVs; a second die stacked on the first die and including a plurality of second TSVs, wherein the plurality of second TSVs include second NTSVs and a second RTSV for the TSV repair units, and the second NTSVs and the second RTSV are respectively arranged opposite to the first NTSVs and the first RTSV and are respectively connected to the first NTSVs and the first RTSV by electrical connection structures; and a repair circuit.
H01L 25/065 - Assemblies consisting of a plurality of individual semiconductor or other solid-state devices all the devices being of a type provided for in a single subclass of subclasses , , , , or , e.g. assemblies of rectifier diodes the devices not having separate containers the devices being of a type provided for in group
H01L 21/66 - Testing or measuring during manufacture or treatment
2.
CIRCUIT SELF TEST APPARATUS AND OPERATING METHOD THEREOF
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Kang, Sungho
Park, Jongho
Abstract
A circuit self-test apparatus includes a circuit under test including a plurality of scan chains, where each of the plurality of scan chains includes a plurality of scan cells, and where each of the plurality of scan chains are configured based on a weight and a correlation obtained from a determination pattern input into each of the plurality of scan cells, and a test circuit including a linear feedback shift register (LFSR) configured to generate a random pattern for each of the plurality of scan chains, where the test circuit is configured to generate a modification pattern for each of the plurality of scan chains based on the random pattern and a state of the LFSR.
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Gee, Heon Yung
Bok, Jinwoong
Hong, Ji Won
Abstract
The present invention provides a composition for preventing or treating noise-induced hearing loss, the composition containing a CHOP protein inhibitor as an active ingredient. The present invention can achieve a fundamental treatment for permanent hearing loss, for which there is no realistic therapeutic agent, by reversibly restoring a permanent threshold shift (PTS) caused by noise. Furthermore, the present invention provides a screening method capable of rapidly searching for efficient therapeutic candidates for noise-induced hearing loss with high reliability by using the CHOP protein as a screening target. In addition, the present invention provides a composition for diagnosing noise-induced hearing loss, the composition containing an agent for measuring the expression level of the CHOP protein or a nucleic acid encoding same, and a method for diagnosing noise-induced hearing loss using the composition. The present invention predicts, with high reliability, whether a threshold shift caused by noise exposure is temporary or permanent, and thus can be useful for quickly identifying subjects in need of treatment and establishing treatment strategies early.
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
A61K 31/192 - Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
A61K 31/575 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
INJE UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (Republic of Korea)
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Jeong, Seong Ho
Lee, Phil Hyu
Kim, Yeon Ju
Shin, Jin Young
Abstract
The present invention relates to a pharmaceutical composition for treatment of Parkinson's disease, containing sitagliptin as an active ingredient. It has been identified that, among patients with Parkinson's disease with comorbid diabetes, a sitagliptin-administered group exhibited less dopaminergic neuron loss at the time of diagnosis in comparison to a non-administered group, and in comparison even to a group without diabetes, the loss of dopaminergic neurons was milder. It has been also identified that oral administration of the sitagliptin in an animal model of Parkinson's disease improves intestinal inflammation and microbial groups, alleviates deposition of α-synuclein in the intestine, and alleviates deposition of α-synuclein in brain tissue, and thus the sitagliptin is provided as a novel treatment for Parkinson's disease on the basis of the gut-brain axis.
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
CHUNG ANG UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION (Republic of Korea)
Inventor
Shin, Sung Jae
Kim, Lee-Han
Jeon, Yae Rin
Kim, Jae Hyun
Jung, Jin Yi
Abstract
The present invention relates to a novel febuxostat derivative compound and a composition comprising same as an active ingredient for preventing or treating inflammatory or autoimmune diseases. The compounds of the present invention significantly reduce the expression of inflammatory cytokines in macrophages even at low doses, thereby effectively suppressing excessive inflammatory responses, and can thus be advantageously used for long-term administration in the treatment of inflammatory diseases, which are, for the most part, chronic.
C07D 333/24 - Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
C07D 307/54 - Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
C07D 207/337 - Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
C07D 209/14 - Radicals substituted by nitrogen atoms, not forming part of a nitro radical
6.
METHOD OF MANUFACTURING TRANSPARENT ELETRODE FOR SOLAR CELL USING LIQUID METAL
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Lee, Yeong Hee
Park, Jang Ung
Kim, Su Min
Chung, Won Gi
Abstract
A method for manufacturing a transparent electrode for a solar cell includes forming sequential layers: a lower sacrificial layer, a protective layer, and an upper sacrificial layer on a substrate. The upper sacrificial layer is partially removed to expose the protective layer, and a liquid metal layer is deposited on the exposed surfaces. The metal layer remains in a specific pattern after removing the upper sacrificial layer. A polymer layer is formed around the patterned metal layer, and the protective, metal, and polymer layers are separated from the substrate by removing the lower sacrificial layer. Finally, the protective layer is removed to produce the liquid metal transparent electrode.
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Hwang, Eunju
Song, William Jinho
Park, Chanho
Kim, Euijun
Abstract
A system-on-chip (SoC) includes a first processor including a first performance monitor configured to perform monitoring on a plurality of first performance parameters including first performance parameters. The SoC also includes a power prediction circuit configured to predict a power consumption of the first processor based on count values of the first performance parameters collected by the first performance monitor, and a power management unit configured to manage power supplied to the first processor based on a prediction result of the power prediction circuit.
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Min, Byung-Wook
Kim, Sungeun
Abstract
The present disclosure provides a reconfigurable intelligent surface and a manufacturing method therefor, the surface comprising: a plurality of RF-path units having each of a plurality of radiators, a plurality of phase shifters, and first connectors, and having the same size and shape; and a DC-path, which includes a plurality of bias controllers for controlling the plurality of phase shifters of the RF-path units, and a plurality of second connectors coupled to the first connectors of each of the plurality of RF-path units, and thus manufacturing costs can be reduced and modification into various sizes and shapes according to the usage environment is possible.
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Yoon, Jun Young
Sung, Jong Min
Kim, Jae Hyun
Lee, Sang Min
Kang, Bo Min
Park, Jeong Min
Jeon, Byung Wook
Lee, Kang Hee
Jung, Jae Heon
Abstract
The method for verifying the axial flux motor design variable includes: a first step of converting a cylindrical coordinate system design variable of the axial flux motor into an orthogonal coordinate system design variable; a second step of deriving a orthogonal coordinate system magnetic field from the orthogonal coordinate system design variable; a third step of deriving a cylindrical coordinate system magnetic field from the derived orthogonal coordinate system magnetic field; a fourth step of deriving one or more verification target physical quantities selected from a group consisting of magnetic flux linkage, counter electromotive force, inductance, and torque from the cylindrical coordinate system magnetic field; and a fifth step of comparing the verification target physical quantity with a predetermined reference value and determining whether a verification condition thereon is achieved, based on the comparing result.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (Republic of Korea)
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Min, Young Gi
Sung, Jung Joon
Ban, Jae Jun
Shin, Ha Young
Abstract
The present invention relates to multiparameter flow cytometry for simultaneously detecting node-paranodal autoantibodies in inflammatory neuropathy patients. Specifically, four different types of cells expressing four different node-paranodal autoantigens (NF155, CNTN1, CASPR1 and NF186) and fluorescent markers are prepared and mixed, the mixed four types of cells are reacted with a sample from a patient with inflammatory peripheral neuropathy, and then flow cytometry is performed so that it is identified that autoantibodies against the four types of autoantigens can be detected simultaneously and the isotypes thereof can be determined, and thus, the cells and flow cytometry using same can be effectively used in autoantibody test for diagnosing, monitoring or predicting the treatment responses of autoimmune nodopathies from among inflammatory neuropathies.
G01N 33/58 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving labelled substances
G01N 33/533 - Production of labelled immunochemicals with fluorescent label
G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
G01N 33/564 - ImmunoassayBiospecific binding assayMaterials therefor for pre-existing immune complex or autoimmune disease
G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
11.
COMPOSITION FOR MODIFYING ELECTRODE ACTIVE MATERIAL COMPRISING CELLULOSE OR FUNCTIONALIZED CELLULOSE, ELECTRODE ACTIVE MATERIAL MODIFIED WITH CELLULOSE OR FUNCTIONALIZED CELLULOSE, AND SECONDARY BATTERY COMPRISING SAME
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Lee, Sang-Young
Ryou, Myeong-Hwa
Abstract
The present invention relates to: a composition for modifying the surface of an electrode active material for a secondary battery, wherein the composition comprises cellulose, modified cellulose, or a mixture thereof; an electrode active material for a secondary battery, wherein the electrode active material is coated with cellulose, modified cellulose, or a mixture thereof; and a secondary battery comprising same. According to the present invention, a dry electrode can be manufactured by excluding the use of a fluorine-based binder or reducing the amount of the used fluorine-based binder, and excellent dispersibility and adhesion are achieved without using a PTFE binder conventionally used as a dry electrode binder, thereby enabling the production of a high-capacity thick film electrode.
H01M 4/525 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of nickel, cobalt or iron of mixed oxides or hydroxides containing iron, cobalt or nickel for inserting or intercalating light metals, e.g. LiNiO2, LiCoO2 or LiCoOxFy
H01M 4/505 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese of mixed oxides or hydroxides containing manganese for inserting or intercalating light metals, e.g. LiMn2O4 or LiMn2OxFy
H01M 4/131 - Electrodes based on mixed oxides or hydroxides, or on mixtures of oxides or hydroxides, e.g. LiCoOx
H01M 4/1391 - Processes of manufacture of electrodes based on mixed oxides or hydroxides, or on mixtures of oxides or hydroxides, e.g. LiCoOx
H01M 10/0525 - Rocking-chair batteries, i.e. batteries with lithium insertion or intercalation in both electrodesLithium-ion batteries
C08B 15/00 - Preparation of other cellulose derivatives or modified cellulose
12.
MULTIPLEX IMMUNOASSAY METHOD FOR DIAGNOSING AUTOIMMUNE NODOPATHY
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Shin, Ha Young
Abstract
The present invention relates to a multiplex immunoassay method for diagnosing autoimmune nodopathy and, more specifically, to a multiplex immunoassay method, comprising the steps of: (1) binding CNTN1, Caspr1, NF155, and NF186 proteins each to microspheres having different color codes; (2) mixing the microspheres having different color codes to which the proteins are each bound; (3) treating the mixed microspheres with a biological sample to induce an antigen-antibody reaction; (4) adding a detection antibody; and (5) reading fluorescence information of the microspheres to measure the presence or absence of anti-CNTN1 antibody, anti-Caspr1 antibody, anti-NF155 antibody, or anti-NF186 antibody in the biological sample and quantify amounts thereof, thereby enabling simultaneous testing of four antibodies for rapid diagnosis of autoimmune nodopathy.
Electronics and Telecommunications Research Institute (Republic of Korea)
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Lee, Ha Hyun
Bang, Gun
Kim, Soo Woong
Kim, Jun Sik
Do, Ji Hoon
Bae, Seong Jun
Kang, Jung Won
Choi, Jin Soo
Kim, Seo Ha
Bae, Jeong Min
Uh, Young Jung
Yun, Young Sik
Abstract
A method of decoding an image according to a present disclosure, the method includes decoding a Gaussian parameter and Gaussian embedding for a first Gaussian in a canonical space; obtaining a variation of a Gaussian parameter for the first Gaussian by inputting the Gaussian embedding into a deformation function; and reconstructing a second Gaussian at a target timestamp by applying the variation to the Gaussian parameter for the first Gaussian, wherein the Gaussian embedding is derived individually for each Gaussian.
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Kim, Tae Ho
Chae, Yu Jung
Kim, Eun Ji
Lee, Kyong Ho
Hwang, Seok Ju
Heo, Tae Jung
Abstract
A robot control apparatus can include a memory that stores computer-executable instructions and at least one processor that executes the instructions by accessing the memory. The at least one processor can apply event information about activity of a user, which can be identified from user activity data perceived from a robot, and context information about time and space in which the activity occurs, to a knowledge graph formed by a relation between an event instance regarding the event information and a context instance regarding the context information, obtain user intent data regarding intent of the activity by applying the event instance among instances included in the knowledge graph to a rule creation model for creating information about the intent of the activity, and control the robot such that the robot performs a target task related to expected activity, which can follow the activity, based on the user intent data.
B25J 11/00 - Manipulators not otherwise provided for
15.
METHOD AND SYSTEM FOR PREDICTING GAS ABSORPTION PERFORMANCE OF MIXED ABSORBENT BY USING ARTIFICIAL NEURAL NETWORK, AND METHOD AND SYSTEM FOR DETERMINING OPTIMAL COMPOSITION OF MIXED ABSORBENT
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Kim, Junghwan
Joo, Chonghyo
Kim, Minjae
Abstract
The present invention relates to a method and system for predicting gas absorption performance of a mixed absorbent by using an artificial neural network, and a method and system for determining the optimal composition of a mixed absorbent by using same.
B01D 53/14 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by absorption
16.
SUPERCAPACITOR STATE-OF-HEALTH ESTIMATION SYSTEM AND A METHOD THEREOF
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Noh, Young Woo
Chung, Jong Moon
Park, Jeong Eon
Abstract
A system and a method for supercapacitor state-of-health (SoH) estimation. The system includes: a data detector that monitors charge-discharge data of a supercapacitor mounted in a vehicle; a vehicle controller including a data construction unit that constructs a time series data matrix for each charge/discharge cycle of the supercapacitor based on the charge-discharge data monitored by the data detector, and a neural network model that estimates SoH of the supercapacitor using the time series data matrix for each charge-discharge cycle of the supercapacitor output from the data construction unit; and a display device that displays an estimation result for the SoH of the supercapacitor estimated by the neural network model of the vehicle controller.
G01R 31/392 - Determining battery ageing or deterioration, e.g. state of health
G01R 31/36 - Arrangements for testing, measuring or monitoring the electrical condition of accumulators or electric batteries, e.g. capacity or state of charge [SoC]
G01R 31/367 - Software therefor, e.g. for battery testing using modelling or look-up tables
G01R 31/3842 - Arrangements for monitoring battery or accumulator variables, e.g. SoC combining voltage and current measurements
17.
METHOD OF MANUFACTURING GAMMA-GESE LAYER AND METHOD OF MANUFACTURING MEMORY DEVICE BY USING THE SAME
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Kim, Kwanpyo
Lee, Sol
Jung, Joong-Eon
Abstract
A method of manufacturing a gamma-germanium selenide (γ-GeSe) layer may include coating a first surface of a base layer with a catalytic metal, providing alpha-germanium selenide (α-GeSe) at a first position in a processing space and providing the base layer at a second position in the process space, which is spaced apart from the first position in the processing space, heating the first position in the processing space to a first temperature, supplying gas from the first position to the second position in the processing space, and depositing γ-GeSe on the first surface of the base layer. The base layer may include a crystalline material having a crystal system that is hexagonal.
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Choi, Heonjin
Park, Daerl
Abstract
Disclosed is a chemical vapor deposition method of depositing iridium oxide on a neural probe, provided on a flexible printed circuit board, using ozone gas, the chemical vapor deposition method including: step S100 of introducing an iridium precursor into a reaction chamber (furnace) in which a printed circuit board having a neural probe provided thereon is placed, and purging the inside of the reaction chamber with an inert gas for a predetermined time; and step S200 of introducing ozone (O3) gas and an inert gas into the reaction chamber, and reacting the iridium precursor with the ozone gas at a predetermined reaction temperature, thereby depositing iridium oxide (IrO2) on the surface of the neural probe.
H05K 3/14 - Apparatus or processes for manufacturing printed circuits in which conductive material is applied to the insulating support in such a manner as to form the desired conductive pattern using spraying techniques to apply the conductive material
C23C 16/44 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Jung, Yoon Seok
Song, Yong Bae
Jang, Bo Yeong
Abstract
The present disclosure relates to a method for regenerating a deteriorated solid electrolyte, a solid electrolyte regenerated thereby, and an all-solid-state battery including the regenerated solid electrolyte. The method for regenerating a deteriorated solid electrolyte of the present disclosure allows effective regeneration of a deteriorated solid electrolyte in short time through a simple process by effectively removing a moisture layer and byproducts adsorbed on the surface of the deteriorated solid electrolyte by radiating microwaves to the deteriorated solid electrolyte, and is advantageous in that the structure and ion conductivity retention rate and energy efficiency of the regenerated solid electrolyte are very superior as compared to a pristine solid electrolyte before deterioration. In particular, the solid electrolyte may have a high ion conductivity retention rate after passing through a wet-milling process.
DIAGNOSIS ASSISTANCE DEVICE AND METHOD FOR PREDICTING RISK OF LYMPH NODE METASTASIS BEFORE RESECTION IN EARLY GASTRIC CANCER ON BASIS OF ARTIFICIAL INTELLIGENCE MODEL
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
WAYCEN INC. (Republic of Korea)
Inventor
Kim, Jie Hyun
Kim, Kyung Nam
Oh, Sangil
Abstract
The present disclosure relates to a diagnosis assistance device and method for predicting the risk of lymph node metastasis before resection in early gastric cancer on the basis of an artificial intelligence model. The diagnosis assistance device for predicting whether there is lymph node metastasis in early gastric cancer according to the present disclosure comprises: a communication unit configured to receive a gastroscope image of a patient and medical record data of the patient; and a processor including an artificial intelligence model for predicting a lymph node metastasis possibility by using the gastroscope image and the medical record data as input data, wherein the processor generates prescription data related to a gastric cancer treatment method on the basis of a result of the lymph node metastasis prediction.
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 30/20 - ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
A61B 1/273 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor for the upper alimentary canal, e.g. oesophagoscopes, gastroscopes
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
21.
FEATURE VECTOR STORAGE-BASED CLASS-INCREMENTAL SEMANTIC SEGMENTATION LEARNING DEVICE AND METHOD
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Ham, Bum Sub
Oh, Young Min
Baek, Dong Hyeon
Abstract
A class-incremental semantic segmentation learning method includes: obtaining an incremental semantic segmentation neural network by performing incremental learning on the basis of incremental learning data for an additional incremental class on a previously trained existing semantic segmentation neural network to classify an existing learning class according to existing learning data; after incremental learning with class-based feature vectors, extracted from a previous feature map estimated by the previously trained existing semantic segmentation neural network and pre-stored, obtaining a class-based representative feature vector by estimating a correlation between an existing feature map and an incremental feature map obtained from the existing semantic segmentation neural network and the incremental semantic segmentation neural network, respectively; performing transformation learning which sets a class-based rotation matrix on the basis of the class-based representative feature vector; and performing learning by inputting the transformed class-based feature vector into the semantic segmentation neural network using the class-based rotation matrix.
G06V 20/70 - Labelling scene content, e.g. deriving syntactic or semantic representations
G06V 10/764 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using classification, e.g. of video objects
G06V 10/82 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks
22.
DEVICE AND METHOD FOR PROVIDING ULTRASOUND IMAGE MEASUREMENT GUIDE BASED ON DEEP LEARNING
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Lee, Joon Sang
Hong, Ju Young
Cho, Ara
Kim, Jun Hong
Abstract
The present invention relates to a device and a method for providing an ultrasound image measurement guide based on deep learning. According to the present invention, provided are a device and a method for providing an ultrasound image measurement guide based on deep learning, capable of quickly and accurately acquiring a field ultrasound in an emergency situation even by a less experienced medical expert by providing a guide to more quickly and accurately measure a field diagnosis ultrasound by utilizing deep learning.
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
G16H 30/20 - ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Hwang, Seong Ju
Sun, Dong Hoon
Abstract
Disclosed is a method for preparing a layered metal phosphide hybrid catalyst. The method for preparing a layered metal phosphide hybrid catalyst comprises: a first step for preparing a layered metal double-layer hydroxide nanosheet structure represented by chemical formula 1; and a second step for heat-treating the metal double-layer hydroxide nanosheet structure and a phosphorus (P)-containing precursor material in a reducing atmosphere to convert the layered metal double-layer hydroxide nanosheet structure into a layered metal phosphide hybrid nanosheet structure.
POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION (Republic of Korea)
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Kim, Ki Hean
Lee, Jung Bin
Jeon, Su Il
Park, No Seong
Yun, Ji Eun
Kim, Seong Han
Joo, Chulmin
Abstract
Proposed is a microscope enabling differential phase contrast imaging of oblique focal plane and a method for operating the same, which can image a large area 3D surface by scanning and photographing in a horizontal direction a focal plane tilted by applying an oblique plane microscopy (OPM) technology that tilts a focal plane of a photographing area of a microscope. The microscope includes a sample photographing module for photographing a sample and an imaging generator for generating a sample imaging on the basis of an image of the sample photographed in the sample photographing module, wherein the sample photographing module includes a light source unit for radiating light to the sample, an objective lens for obtaining transmitted light from the sample, and an imaging information acquisition unit for obtaining imaging information of the sample through the transmitted light.
GACHON UNIVERSITY OF INDUSTRY-ACADEMIC COOPERATION FOUNDATION (Republic of Korea)
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
MAGICBULLETTHERAPEUTICS CO., LTD. (Republic of Korea)
Inventor
Pyo, Jong-Ok
Lee, Myung-Shik
Chang, Keun-A
Kim, Jinho
Kim, Yeji
Ko, Young Tag
Kang, Ji Hee
Sim, Taebo
Sandip, Sengupta
Park, Chan Jung
Ko, Minjoo
Choi, Ha Soon
Abstract
The present disclosure relates to a compound that targets tau and induces or activates autophagy, a preparation method therefor, and uses thereof More specifically, the present invention relates to a compound that targets tau protein and promotes the formation of autophagosomes via lysosomal pathways, a preparation method therefor, and a treatment of tau protein-related diseases using same.
C07D 473/18 - Heterocyclic compounds containing purine ring systems with oxygen, sulfur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
A61K 47/54 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
A61K 31/522 - Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Kim, Hyun Jae
Park, Ji Yeong
Min, Won Kyung
Song, Sun Min
Son, Hye Jin
Abstract
A stretchable display device includes a plurality of unit display areas, wherein each of the unit display areas is composed of a plurality of stretchable display component placement areas, and wherein either a stretchable wiring portion or a pixel portion is arranged in each of the stretchable display component placement areas.
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Cheon, Seonyoung
Lee, Yongwoo
Kim, Dongkwan
Lee, Ju Min
Kim, Hanjun
Shin, Junbum
Kim, Taekyung
Jung, Sunchul
Park, Sanghoon
Abstract
Disclosed is an electronic apparatus. The electronic apparatus includes an interface, a memory in which a compiler is stored, and a processor. The processor is configured to based on a first type of program is input through the interface, convert the program into a second type of program for processing a homomorphic encrypted ciphertext using the compiler, and identify a time when a bootstrapping is required to expand a plaintext space of the homomorphic encrypted ciphertext in the conversion process, and generate a code for inserting a bootstrapping operation at the identified time.
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Kwon, Soo Young
Lee, Hun Ju
Abstract
The present invention relates to a counseling quality evaluation system using emotional words, which is performed by a control server having a database and a calculation function, the counseling quality evaluation system comprising: an information input unit (100) in which voice counseling files of a counselor and a client are inputted; an information processing unit (200) which converts voice information of the counselor and the client stored in the voice counseling files into text information; an emotional word module unit (300) which extracts emotional words preset for each counselor and client from the converted text information; an emotional category module unit (400) which calculates an emotional category to which the emotional words extracted from the emotional word module unit (300) belong; and a counseling quality evaluation unit (500) which evaluates the counseling quality of the counselor by comparing the emotional category and the emotional words used by the client and the counselor.
G10L 25/63 - Speech or voice analysis techniques not restricted to a single one of groups specially adapted for particular use for comparison or discrimination for estimating an emotional state
G10L 15/22 - Procedures used during a speech recognition process, e.g. man-machine dialog
G10L 25/69 - Speech or voice analysis techniques not restricted to a single one of groups specially adapted for particular use for evaluating synthetic or decoded voice signals
KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (Republic of Korea)
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Lee, Hyuk
Kim, Mee Hyein
Kwak, Jae Sung
Park, A Reum
Lee, Joon Ho
Shin, Sang Joon
Yang, Jaemoon
Chang, Sung Youn
Kim, Tae Il
Hwang, Ji Eon
Abstract
The present invention relates to a pharmaceutical composition comprising a benzenesulfonamide-substituted heterobicyclic derivative, which is an IRP2 disrupting substance, as an active ingredient for preventing or treating cancer. The present invention can provide a benzenesulfonamide-substituted heterobicyclic derivative compound which interferes the binding of IRP2 to IRE to induce reprogramming of iron metabolism in cancer cells, thereby killing solid cancer, especially colorectal cancer cells.
A61K 31/437 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Kim, Hyun Jae
Son, Hye Jin
Min, Won Kyung
Park, Ji Yeong
Song, Sun Min
Abstract
Proposed is a stretchable display device. The stretchable display device includes a plurality of main pixels, a plurality of hidden pixels, a first main pixel, and a first hidden pixel corresponding to the first main pixel. A first hidden pixel value is determined on the basis of a first main pixel value.
H10H 29/34 - Active-matrix LED displays characterised by the geometry or arrangement of subpixels within a pixel, e.g. relative disposition of the RGB subpixels
G09G 3/00 - Control arrangements or circuits, of interest only in connection with visual indicators other than cathode-ray tubes
G09G 3/32 - Control arrangements or circuits, of interest only in connection with visual indicators other than cathode-ray tubes for presentation of an assembly of a number of characters, e.g. a page, by composing the assembly by combination of individual elements arranged in a matrix using controlled light sources using electroluminescent panels semiconductive, e.g. using light-emitting diodes [LED]
H10H 29/49 - Interconnections, e.g. wiring lines or terminals
31.
COMPOSITE CATALYST STRUCTURE, MANUFACTURING METHOD THEREFOR, WATER ELECTROLYSIS APPARATUS COMPRISING SAME, AND METAL-AIR SECONDARY BATTERY
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Hwang, Seong Ju
Yoon, Woo Sik
Abstract
A composite catalyst structure having catalytic activity for an oxygen evolution reaction (OER) or an oxygen reduction reaction (ORR) is disclosed. The composite catalyst structure may comprise: a porous metal support; a metal nitride nanosheet grown from the porous metal support; and a layered double hydroxide nanosheet disposed on the surface of the metal nitride nanosheet.
C25B 11/091 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of at least one catalytic element and at least one catalytic compoundElectrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of two or more catalytic elements or catalytic compounds
B01J 35/50 - Catalysts, in general, characterised by their form or physical properties characterised by their shape or configuration
B01J 35/73 - Catalysts, in general, characterised by their form or physical properties characterised by their crystalline properties, e.g. semi-crystalline having a two-dimensional layered crystalline structure, e.g. layered double hydroxide [LDH]
B01J 37/10 - Heat treatment in the presence of water, e.g. steam
B01J 23/02 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the alkali- or alkaline earth metals or beryllium
B01J 23/70 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper
C25B 1/04 - Hydrogen or oxygen by electrolysis of water
C25B 9/23 - Cells comprising dimensionally-stable non-movable electrodesAssemblies of constructional parts thereof with diaphragms comprising ion-exchange membranes in or on which electrode material is embedded
32.
LAYERED DOUBLE HYDROXIDE CATALYST, METHOD FOR PRODUCING SAME, WATER ELECTROLYSIS APPARATUS COMPRISING SAME, AND METAL-AIR SECONDARY BATTERY
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Hwang, Seong Ju
Jin, Xiaoyan
Park, Yeon Hu
Abstract
Disclosed herein is a layered double hydroxide catalyst having catalytic activity for an oxygen evolution reaction (OER) or an oxygen reduction reaction (ORR). The layered double hydroxide catalyst has a chemical structure represented by chemical formula 1. [Chemical formula 1] [M11-(a+b)1-(a+b)M2aaY3+b22][An-(a+b)/22O. In chemical formula 1, M1is a first transition metal positive electrode having an oxidation state of +2, M2 is a second transition metal positive electrode having an oxidation state of +3, A is an interlayer negative electrode having an oxidation state of -n, a and b are positive real numbers satisfying the condition "0
C25B 11/091 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of at least one catalytic element and at least one catalytic compoundElectrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of two or more catalytic elements or catalytic compounds
H01M 12/08 - Hybrid cellsManufacture thereof composed of a half-cell of a fuel-cell type and a half-cell of the secondary-cell type
B01J 23/83 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups with rare earths or actinides
B01J 35/73 - Catalysts, in general, characterised by their form or physical properties characterised by their crystalline properties, e.g. semi-crystalline having a two-dimensional layered crystalline structure, e.g. layered double hydroxide [LDH]
C25B 1/04 - Hydrogen or oxygen by electrolysis of water
C25B 9/23 - Cells comprising dimensionally-stable non-movable electrodesAssemblies of constructional parts thereof with diaphragms comprising ion-exchange membranes in or on which electrode material is embedded
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Kim, Joo Young
Kim, Yerim
Namkung, Wan
Lee, Donghyuk
Oh, Jinkyung
Abstract
The present invention relates to a composition comprising an anti-CD20 antibody and a PIKfyve inhibitor for preventing or treating CD20 positive cancer such as B cell lymphoma. The present invention can maximize the anticancer effect of an anti-CD20 antibody, specifically, obinutuzumab, by co-administering an anti-CD20 antibody and a PIKfyve inhibitor, which is a negative regulator of a tumor cell killing mechanism thereof. In addition, by using PIKfyve as a screening target, the present invention can rapidly identify, with high reliability, combination therapy candidate agents that can synergistically enhance the direct cell death (DCD), lysosomal membrane permeabilization (LMP), and subsequent cancer cell-killing activity of anti-CD20 antibodies.
A61K 39/395 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum
A61K 31/5377 - 1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
A61K 31/4439 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A61P 35/02 - Antineoplastic agents specific for leukemia
C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
A61K 39/00 - Medicinal preparations containing antigens or antibodies
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
CHUNG ANG UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION (Republic of Korea)
Inventor
Hong, Jin Kee
Lee, Sang Min
Abstract
The present invention relates to a micro-electrical stimulation scar band comprising: an upper mat; a lower mat; and a pair of wires spaced apart from each other along the circumferential direction of the outer surface of the lower mat and formed to be wound, wherein the wires form one closed ring. By continuously providing micro-electrical stimulation to a lesion part such as a wound or a scar without an external power source, the effects of promoting and activating healing of the wound, removing the scar, and regenerating the wound into normal skin can be achieved.
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Kim, Woochul
Choi, Yousung
Park, Sungjin
Kim, Jiyong
Abstract
A thermoelectric leg, a manufacturing method for same, and a thermoelectric device comprising same are disclosed. The method for manufacturing the thermoelectric leg may comprise: a sintered solid formation step comprising a basic sintering step of sintering, by hot pressing in a mold, a soluble material powder or a semiconductor material powder, and an additional sintering step of additionally sintering, by hot pressing in another mold, the sintered solid and the soluble material powder or the semiconductor material powder one or more times so as to form a sintered solid for dissolution, comprising both the soluble material and the semiconductor material; and a hollow formation step of forming a hollow by exposing the soluble material in the sintered solid for dissolution to a solvent and selectively removing same.
H10N 10/17 - Thermoelectric devices comprising a junction of dissimilar materials, i.e. devices exhibiting Seebeck or Peltier effects operating with only the Peltier or Seebeck effects characterised by the structure or configuration of the cell or thermocouple forming the device
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Park, Yongjun
Jung, Kiung
Abstract
Disclosed herein are an apparatus and method for providing execution plans of multiple mixed-precision deep learning models based on a multi-precision NPU. The apparatus includes a memory, and a processor electrically connected to the memory. The processor is configured to form a multi-precision Neural Processing Unit (NPU) including a processing element (PE) composed of multiple Micro-PEs, to generate multiple mixed-precision deep learning models that perform multiple precision operations requiring different degrees of precision in a model execution process, and to generate the execution plans for executing the multiple mixed-precision deep learning models on the multi-precision NPU.
G06F 9/50 - Allocation of resources, e.g. of the central processing unit [CPU]
G06F 15/80 - Architectures of general purpose stored program computers comprising an array of processing units with common control, e.g. single instruction multiple data processors
37.
APPARATUS AND METHOD FOR GENERATING SYMPTOM OCCURRENCE PREDICTION INFORMATION
KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (Republic of Korea)
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Cho, Chul Hyun
Park, Yu Rang
Jang, Soo Young
Abstract
The present specification discloses an apparatus and method for generating symptom occurrence prediction information. The apparatus for generating symptom occurrence prediction information, according to the present specification, may include: a transmitting and receiving unit that receives, from a digital device, demographic information, psychological test scales, biometric information, and daily information of a patient and transmits, to the digital device, prediction information and feedback information about whether a panic symptom has occurred; a pattern information generation unit for generating information related to a pattern change of the biometric information (hereinafter, referred to as "pattern information"); a prediction information generation unit for generating the prediction information by using the demographic information, the psychological test scales, the pattern information, and the daily information of the patient; and a feedback generation unit for generating the feedback information according to the prediction information.
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 20/70 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mental therapies, e.g. psychological therapy or autogenous training
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
G16H 10/20 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for electronic clinical trials or questionnaires
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Chang, Jiwon
Ma, Jiwon
Lee, Changwook
Abstract
A trench-shaped ternary CMOS device includes a common drain provided at the bottom, a 2D phase change material layer composed of a 2D phase change material and stacked on the top of the common drain, a common gate provided over the 2D phase change material layer, a 2D n-type channel semiconductor material layer that is vertically stacked with respect to the 2D phase change material layer and connected to one end of the 2D phase change material layer and that has one side surface that faces one end of the common gate, and a 2D p-type channel semiconductor material layer that is vertically stacked with respect to the 2D phase change material layer and connected to an opposite end of the 2D phase change material layer and that has one side surface that faces an opposite end of the common gate.
H10D 30/47 - FETs having zero-dimensional [0D], one-dimensional [1D] or two-dimensional [2D] charge carrier gas channels having 2D charge carrier gas channels, e.g. nanoribbon FETs or high electron mobility transistors [HEMT]
H10D 62/80 - Semiconductor bodies, or regions thereof, of devices having potential barriers characterised by the materials
DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY (Republic of Korea)
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Hwang, Jae Youn
Lee, Moon Hwan
Kim, Hee Man
Abstract
The present invention relates to an endoscope-attachable ultrasonic imaging device comprising: a body having a space therein; an electric motor embedded in the lower portion of the body to selectively rotate a rotary shaft in response to a driving signal applied from the outside; a first ultrasonic transducer provided in the upper portion of the body and emitting first ultrasonic waves in the corresponding frequency band to a target and then receive first ultrasonic waves reflected by the target; a second ultrasonic transducer provided inside the body and emitting second ultrasonic waves in the relevant frequency band to the target and then receiving second ultrasonic waves reflected from the target; an acoustic mirror member provided inside the body and reflecting ultrasonic waves emitted by the first and second ultrasonic transducers, in the circumferential direction; and a magnetic coupler provided between the electric motor and the acoustic mirror member to rotate the acoustic mirror member around the center of the body by means of rotational power generated by the electric motor. The endoscope-attachable ultrasonic imaging device can be attached to the end of a general endoscope probe to provide 360° ultrasonic images in addition to those of existing endoscopes, thereby providing improved accuracy in lesion diagnosis.
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Min, Byung-Wook
Kim, Sungeun
Chun, Dohoon
Lee, Jaekwan
Abstract
Provided are a Reconfigurable Intelligent Surface (RIS) unit, and a control apparatus and method thereof. The control apparatus includes a voltage determination module that is activated when a first power supply voltage is applied, receives serial data, and obtains a plurality of level determination signals, a voltage fixing module that is driven when a second power supply voltage is applied, and stores a plurality of phase control signals obtained by level-shifting each of the plurality of level determination signals transmitted from the voltage determination module, and a phase shifting module configured to adjust a phase of a signal received by each of a plurality of radiators according to the plurality of phase control signals.
H04B 7/04 - Diversity systemsMulti-antenna systems, i.e. transmission or reception using multiple antennas using two or more spaced independent antennas
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Lee, Su Hwan
Kim, Kyu Bom
Kim, Kyu Seok
Kim, Yeon Kyeong
Abstract
This operation method of a pulmonary disease prediction system operated by at least one processor comprises the steps of: acquiring a chest radiographic image of a patient and a plurality of lung sound intensity images acquired from at least one chest region of the patient; extracting a lung region from the chest radiographic image so as to generate a lung region radiographic image; warping the plurality of lung sound intensity images to the extracted lung region so as to generate a plurality of lung sound intensity images warped to the lung region; and acquiring a pulmonary disease prediction result predicted from the lung region radiographic image and the plurality of warped lung sound intensity images by using a pulmonary disease prediction model trained to predict pulmonary disease from an input image.
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 30/20 - ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
A61B 6/50 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific body partsApparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment specially adapted for specific clinical applications
A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
G06T 5/50 - Image enhancement or restoration using two or more images, e.g. averaging or subtraction
42.
COATING COMPOSITION COMPRISING ZWITTERION, AND TRANSPARENT ORTHODONTIC DEVICE SURFACE-COATED USING SAME
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Sim, Un Seob
Kim, Hoon
Jang, Soon Ho
Choi, Sung Hwan
Kwon, Jae Sung
Mangal, Utkarsh
Abstract
The present invention relates to a coating composition comprising a zwitterion and a transparent orthodontic device surface-coated using same. By forming a coating layer on the surface of the transparent orthodontic device, the biocompatibility of the transparent orthodontic device can be increased, and thus inflammation can be reduced and compatibility with body tissues enhanced. In addition, the present invention relates to a transparent orthodontic device in which the attachment of microbial organisms and the formation of biofilms that can cause infections and complications can be prevented on the surface of the transparent orthodontic device having a coating layer formed by the coating composition.
C09D 4/00 - Coating compositions, e.g. paints, varnishes or lacquers, based on organic non-macromolecular compounds having at least one polymerisable carbon-to-carbon unsaturated bond
C08F 2/50 - Polymerisation initiated by wave energy or particle radiation by ultraviolet or visible light with sensitising agents
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Sim, Un Seob
Kim, Hoon
Jang, Soon Ho
Choi, Sung Hwan
Kwon, Jae Sung
Mangal, Utkarsh
Abstract
The present invention relates to a coating composition comprising zwitterions and a transparent orthodontic device surface-coated using same. As a coating layer is formed on the surface of the transparent orthodontic device, biocompatibility of the transparent orthodontic device can be increased, thereby reducing inflammation and improving compatibility with body tissues. In addition, the present invention relates to a transparent orthodontic device which can prevent the formation of a biofilm capable of causing adhesion, infection, and complications of microbial organisms on the surface of the transparent orthodontic device on which a coating layer is formed by the coating composition.
C09D 4/00 - Coating compositions, e.g. paints, varnishes or lacquers, based on organic non-macromolecular compounds having at least one polymerisable carbon-to-carbon unsaturated bond
C08F 230/02 - Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing phosphorus
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION (Republic of Korea)
Inventor
Kim, Joo Young
Kim, Woo Taek
Cho, Hyung Joo
Ahn, Tae Young
Kwon, Beom Jun
Cho, Na Hyun
Seo, Dong Hye
Hwang, Inhwan
Abstract
The present invention relates to: an antigen-binding fragment of an anti-IL-4Rα antibody expressed in plant cells; and a composition for preventing or treating inflammation or autoimmune diseases comprising same as an active ingredient. The present invention provides an antigen-binding fragment of an anti-IL-4Rα antibody, specifically a scFv of dupilumab, expressed in plant cells, which exhibits binding affinity equal to or greater than dupilumab with respect to IL-4Rα while showing significantly increased epithelial cell permeability. Accordingly, the antigen-binding fragment of the present invention can be effectively used as an excellent anti-inflammatory pharmacological component which is locally administered to epithelial tissues, thereby minimizing a systemic effect on immune activity, concentrating a pharmacological effect on a lesion, and greatly improving patient administration convenience.
C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
C07K 7/06 - Linear peptides containing only normal peptide links having 5 to 11 amino acids
C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Koo, Bon Nyeo
Kim, Jong Youl
Sim, A Young
Abstract
Porphyromonas gingivalisPorphyromonas gingivalisPorphyromonas gingivalis, of the present invention, reduces the expression of IGFBP2, Aß and p-Tau and reduces the level of blood insulin, and thus can be used as an effective composition for a dementia vaccine or a composition for preventing, alleviating or treating dementia, and can be effectively used in a method for preventing or treating dementia.
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Kim, Hyun Jae
Kwak, Kyungmoon
An, Jong Bin
Chung, Jusung
Choi, Dong Hyun
Ahn, Jong Hyuk
Lee, Moon Ho
Lee, Ju Hyun
Hong, Seok Min
Abstract
A capacitor-less stacked DRAM cell based on a vertical transistor includes a first vertical transistor and a second vertical transistor, and each of the first vertical transistor and the second vertical transistor includes a spacer, a source disposed on an upper surface of the spacer, a drain disposed adjacent to a lower portion of a side surface of the spacer, a channel disposed along an upper surface of the drain, an upper portion of the side surface of the spacer, and an upper surface of the source, a gate insulator disposed along a side surface and an upper surface of the channel, and a gate electrode disposed along a side surface and an upper surface of the gate insulator.
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Kim, Hyun Jae
Park, Kyungho
An, Jong Bin
Chung, Jusung
Choi, Dong Hyun
Kwak, Kyungmoon
Seo, You Jin
Kim, Beom Soo
Lee, Moon Ho
Moon, Kunho
Abstract
The present disclosure relates to a 2T0C-based memory cell. The 2T0C-based memory cell includes a first transistor and a second transistor connected through a storage node, a first word line connected to the first transistor and controlling an on/off state of the first transistor through an operation of applying a voltage, a second word line connected to the second transistor and controlling an on/off state of the second transistor such that data stored in the memory cell are read, and a single bit line connected to the first transistor and the second transistor and allowing the storage node to be charged or discharged depending on a voltage applied to the single bit line.
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Jung, Seong-Ook
Ha, Dong-Gyun
Kim, Do-Han
Abstract
An apparatus for adaptively adjusting refresh timing of a CIM based on eDRAM includes a replica array including a plurality of replica MAC arrays, each having replica cells arranged in a direction and number according to the direction and number in which memory cells performing MAC operations together in a CIM cell array are arranged and a refresh determination module that compares voltage levels of signals output from each of the plurality of replica MAC arrays with MAC operation results according to weights stored in replica cells of the plurality of replica MAC arrays and activates a refresh enable signal for refreshing memory cells of the CIM cell array.
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Sung, Hak-Joon
Yu, Seung Eun
Chung, Seyong
Kim, Jueun
Abstract
The present invention relates to a drug delivery system comprising liposomes containing aspirin. The drug delivery system of the present invention is loaded onto monocytes so that only cells that cause inflammation can be targeted, and the monocytes onto which the drug delivery system is loaded can be delivered to platelets while circulating throughout the whole body for a long period of time, thereby having an excellent effect of reducing the activation of platelets.
A61K 9/127 - Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
A61K 47/46 - Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
A61K 31/616 - Salicylic acidDerivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Jung, Seong Ook
Lim, Do Yoon
Lim, Sehee
Ko, Donghan
Abstract
According to various embodiments of the present invention, an input/output sense amplifier circuit in a sense amplifier circuit includes a 1-1 transistor having a source connected to a first global input/output line, a 1-2 transistor having a source connected to a second global input/output line, and a metal-oxide-semiconductor capacitor (MOSCAP) configured to connect a gate of the 1-1 transistor to a gate of the 1-2 transistor.
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Choi, Woo Young
Kim, Hyun Kyu
Lee, Jae Ho
Abstract
A WDM receiver based on a ring resonator according to the present disclosure may include a plurality of ring resonator filters configured to receive a WDM optical signal, and each configured to have a heater; a plurality of photodetectors configured to convert the optical signal into a current; and a temperature controller configured to obtain a monitoring voltage corresponding to an output current of corresponding photodetector from each of the plurality of transimpedance amplifying circuits, and control a heater voltage of each of the plurality of ring resonator filters according to the monitoring voltage.
A WDM receiver based on a ring resonator according to the present disclosure may include a plurality of ring resonator filters configured to receive a WDM optical signal, and each configured to have a heater; a plurality of photodetectors configured to convert the optical signal into a current; and a temperature controller configured to obtain a monitoring voltage corresponding to an output current of corresponding photodetector from each of the plurality of transimpedance amplifying circuits, and control a heater voltage of each of the plurality of ring resonator filters according to the monitoring voltage.
A WDM transmitter based on a ring resonator according to the present disclosure may include a plurality of optical modulators configured to output a WDM optical signal and each configured to have a heater; a plurality of photodetectors configured to convert the optical signal into a current; and a temperature controller configured to control a heater voltage of the heater of the plurality of optical modulators according to the monitoring voltage corresponding to an output current of the photodetector.
G02B 6/293 - Optical coupling means having data bus means, i.e. plural waveguides interconnected and providing an inherently bidirectional system by mixing and splitting signals with wavelength selective means
G02F 1/01 - Devices or arrangements for the control of the intensity, colour, phase, polarisation or direction of light arriving from an independent light source, e.g. switching, gating or modulatingNon-linear optics for the control of the intensity, phase, polarisation or colour
G02F 1/313 - Digital deflection devices in an optical waveguide structure
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Park, Taesun
Kang, Wesuk
Abstract
The present disclosure relates to a composition for diagnosing skin aging. The composition of the present disclosure can be usefully used to establish a personalized treatment strategy for skin aging early not only by evaluating the current level of skin aging affected by endogenous factors but also by predicting the genetic risk of future skin aging with high reliability. The present disclosure also relates to a method for screening a skin aging alleviating agent. The screening method of the present disclosure allows accurate and fast screening of a fundamental skin aging inhibitor that goes beyond symptomatic therapy such as moisture supply by restoring collagen production in dermal fibroblasts reduced with aging of the skin's dermis to reversibly restore decreased binding strength, loss of elasticity, loss of moisture, and damage to barrier function of skin tissue.
G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
53.
PHOTORESIST COMPOSITION AND METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE USING THE SAME
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Koh, Chawon
You, Youngmin
Nishi, Tsunehiro
Park, Ji Young
Woo, Sihyun
Abstract
The inventive concept provides a photoresist composition containing an organometallic compound represented by General Formula 1 and a solvent,
The inventive concept provides a photoresist composition containing an organometallic compound represented by General Formula 1 and a solvent,
(MR11R12)a(L)b(OB)c, [General Formula 1]
The inventive concept provides a photoresist composition containing an organometallic compound represented by General Formula 1 and a solvent,
(MR11R12)a(L)b(OB)c, [General Formula 1]
wherein, in General Formula 1, M is a central metal, R11 and R12 are each independently selected from an alkyl group, an aryl group, a heteroaryl group, an allyl group, an alkoxy group, an amino group, a sulfido group, and a halogen group, L is an organic ligand that is a polydentate ligand containing two hydrophobic moieties interconnected by a bridge moiety, B is selected from a hydrogen atom, an alkyl group, and an aryl group, or is omitted, a is an integer between 1 and 8, b is an integer between 1 and 4, c is an integer between 0 and 4, a sum of b and c is an integer between 1 and 4.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (Republic of Korea)
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Cha, Hyuk-Jin
Jo, Beom-Ki
Cho, Seung-Woo
Song, Young Seok
Abstract
The present invention relates to novel lipid nanoparticles capable of liver-specific delivery of mRNA, a manufacturing method therefor, and a liver disease therapeutic agent capable of regenerating the liver by liver-specific delivery of the bio-reprogramming factor mRNA using same. The lipid nanoparticles according to the present invention allow for liver-specific delivery of mRNA at very high efficiency, and the lipid nanoparticles that encapsulate the mRNA-based bio-reprogramming factor mRNA are specifically delivered to liver tissues of an individual requiring liver regeneration to induce short-term expression, thereby easily setting the dose and expression period of a therapeutic agent, leading to a significant reduction in side effects of a therapeutic agent for liver regeneration using an existing cell reprogramming factor.
C12N 15/88 - Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using liposome vesicle
C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Jung, Seong Ook
Kim, Do Han
Jo, Min Young
Abstract
A Compute-In-Memory (CIM) device according to the present disclosure includes first to fourth global bit lines (GBLs) each configured to be divided into two sub-global bit lines having the same capacitance; first to fourth switches each configured to be connected between the sub-global bit lines of each of the first to fourth global bit lines; and a switching circuit configured to generate a differential input voltage for a differential Successive Approximation Register (SAR) Analog-to-Digital Converter (ADC) by reflecting a corresponding bit position from an output voltage of each of the first to fourth global bit lines, the differential SAR ADC being configured to receive the differential input voltage to generate a digital signal.
G11C 7/16 - Storage of analogue signals in digital stores using an arrangement comprising analogue/digital [A/D] converters, digital memories and digital/analogue [D/A] converters
G06F 7/544 - Methods or arrangements for performing computations using exclusively denominational number representation, e.g. using binary, ternary, decimal representation using non-contact-making devices, e.g. tube, solid state deviceMethods or arrangements for performing computations using exclusively denominational number representation, e.g. using binary, ternary, decimal representation using unspecified devices for evaluating functions by calculation
56.
NOVEL FEBUXOSTAT DERIVATIVE AND COMPOSITION FOR HOST-DIRECTED TREATMENT COMPRISING SAME
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
CHUNG ANG UNIVERSITY INDUSTRY ACADEMIC COOPERATION FOUNDATION (Republic of Korea)
Inventor
Shin, Sung Jae
Kim, Lee-Han
Jeon, Yae Rin
Lee, Jumi
Kim, Jae Hyun
Jung, Jin Yi
Abstract
The present invention relates to a novel febuxostat derivative compound and to a composition for preventing or treating a nontuberculous mycobacterial infection, comprising same as an active ingredient. The compound of the present invention efficiently kills nontuberculous mycobacteria, including Mycobacterium shinjukuense and Mycobacterium kansasii, which exhibit low responsiveness to conventional standard therapies and a high frequency of resistance mutation occurrence, via host-directed therapy mediated by host macrophages, and thus can be effectively used as a fundamental therapeutic composition for various complications caused by nontuberculous mycobacteria infections.
A61K 31/437 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Jung, Seong-Ook
Kim, Do-Han
Abstract
An eDRAM cell for a CIM according to the present disclosure includes a first transistor which is connected between a read word line and a read bit line and has a gate connected to a storage node; a second transistor which is connected between a write bit line and the storage node and has a gate connected to a write word line; a first capacitor connected between the storage node and a ground; a third transistor which is connected between a local MAC bit line and a fourth transistor and has a gate connected to the storage node; and a fourth transistor which is connected between the third transistor and the ground and has a gate connected to a MAC word line.
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Choi, Taejin
Kim, Hyungjun
Shin, Hyeonjin
Sohn, Inkyu
Lee, Sangyoon
Chung, Seungmin
Abstract
A semiconductor device includes a semiconductor substrate, a source and a drain provided to be horizontally spaced apart from each other on the semiconductor substrate, a channel layer provided between the source and the drain, a gate insulating layer provided on the channel layer, a gate electrode provided on the gate insulating layer, and a spacer provided to surround the gate electrode, wherein the spacer includes an amorphous boron nitride film.
DAEGU GYEONGBUK INSTITUTE OF SCIENCE AND TECHNOLOGY (Republic of Korea)
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Park, Suk Ho
Lee, Ji Hun
Bang, Seung Min
Abstract
The present invention relates to a multifunctional medical patch for the gastrointestinal tract and a manufacturing method therefor and, more specifically, to a multifunctional medical patch for the gastrointestinal tract, the patch being composed of three layers including an unrolling layer, a guard layer, and a therapeutic layer, wherein the unrolling layer is composed of polyethylene glycol dimethacrylate (PEGDM) and undergoes a swelling phenomenon upon contact with liquid at the target site, the guard layer, located between the unrolling layer and the medical layer, is composed of triethylene glycol dimethacrylate (TEGDM), and the therapeutic layer contains a mucous membrane adhesive material and a medical material and adheres to a target site.
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
SAMSUNG LIFE PUBLIC WELFARE FOUNDATION (Republic of Korea)
Inventor
Shin, Sung Jae
Park, Jihae
Kim, Keueunsan
Jhun, Byung Woo
Kim, Su Young
Abstract
The present invention relates to a composition for differential diagnosis of a Mycobacterium avium complex (MAC) or Mycobacterium tuberculosis (MTb) infectious disease using lipid metabolites, amino acids, and/or amino acid derivatives as markers. The present invention applies the metabolites as markers for predicting, with high accuracy, Mycobacterium avium complex and Mycobacterium tuberculosis infection diseases, which are two diseases having similar clinical expression characteristics, thereby enabling rapid discrimination of the diseases. Accordingly, a patient-customized treatment strategy can be established at an early stage, and thus, the present invention can be helpfully used to significantly improve the survival rate of a patient.
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Lee, Jong-Seung
Lee, Han-Seung
Bhan, Yong-Sun
Kim, Ji-Seok
Abstract
The present invention relates to a derivative compound comprising an amino nicotinamide structure, an isomer thereof or a pharmaceutically acceptable salt thereof, and an antifungal pharmaceutical composition comprising same. More specifically, the present invention provides a benzyloxybenzylamine amino acid derivative having few side effects, and an antifungal agent comprising same. The antifungal agent has a range having antifungal activity against fungi selected from Candida sp., Sporothrix sp., Malassezia sp., Cryptococcus sp., Aspergillus sp., Pneumocystis sp., and Mucor sp.
Uif (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Kim, Minjae
Ro, Won Woo
Lim, Kyeonghoon
Lee, Jiwon
Abstract
A method of operating a computing device according to an aspect of the inventive concept may include accessing a page of a second tier memory, checking a time taken for the access, checking a total number of accesses of the page based on the time taken for the access, and determining whether to terminate promotion of the page to the first tier memory and a timing of the promotion, based on the total number of accesses of the page.
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Lee, Jong-Seung
Lee, Han-Seung
Bahn, Yong-Sun
Kim, Ji-Seok
Abstract
The present invention relates to a derivative compound comprising an amino nicotinamide structure, an isomer thereof or a pharmaceutically acceptable salt thereof, and an antifungal pharmaceutical composition containing same. More specifically, the present invention provides benzyl-oxybenzylamine amino acid derivatives with reduced side effects, and antifungal agents containing same, which exhibit antifungal activity against a spectrum of fungi selected from the group consisting of Candida spp., Sporotrichum spp., Malassezia spp., Cryptococcus spp., Aspergillus spp., Pneumocystis spp., and Mucor spp.
SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (Republic of Korea)
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Kim, Jin Man
Lee, Seung Cheol
Cha, Jae Kook
Abstract
The present disclosure relates to a biomarker for use in the diagnosis or prognostic evaluation of periodontitis, particularly the grade, stage, severity, and/or aggressiveness of periodontitis, and more specifically, the aggressiveness of periodontitis. The present disclosure can be utilized for the early diagnosis and prediction of aggressive periodontitis, aids in developing personalized treatment strategies for each patient with periodontitis, and may greatly improve the clinical management of aggressive periodontitis.
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Park, Yae Won
Park, So Young
Abstract
A material with leather-like properties, an artificial leather material, an artificial leather structure, and a method for preparing the same are disclosed. The material with leather-like properties includes a mushroom extract; and a glycerol-based compound.
D06N 3/02 - Artificial leather, oilcloth, or like material obtained by covering fibrous webs with macromolecular material, e.g. resins, rubber or derivatives thereof with cellulose derivatives
D06N 3/00 - Artificial leather, oilcloth, or like material obtained by covering fibrous webs with macromolecular material, e.g. resins, rubber or derivatives thereof
66.
ANODE-SOLID ELECTROLYTE SUB-ASSEMBLY FOR SOLID SECONDARY BATTERY, SOLID SECONDARY BATTERY INCLUDING THE SAME, AND METHOD OF MANUFACTURING THE SOLID SECONDARY BATTERY
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Kim, Kyounghwan
Park, Jonghyeok
Kim, Kwanghee
Shin, Jaeho
Lee, Yonggun
Abstract
An anode-solid electrolyte sub-assembly for a solid secondary battery, and a method of manufacturing the same, wherein the anode-solid electrolyte sub-assembly includes an anode current collector, a mixed ionic-electronic conductor (MIEC) structure, the mixed ionic-electronic conductor structure between the anode current collector and a solid electrolyte. The mixed ionic-electronic conductor has a plurality of open portions that extend in a direction from the anode current collect towards the solid electrolyte and at least one end of an open portion of plurality of open portions is open. A plurality of lithiophilic metal material particles are disposed on the mixed ionic-electronic conductor structure, an interlayer is disposed between the mixed ionic-electronic conductor structure on which the lithiophilic metal material particles are disposed and the solid electrolyte. The interlayer includes an interlayer material comprising a carbon-containing anode compound; lithium; a mixture of a carbon-containing anode compound and at least one of a second metal or a metalloid; a composite of a carbon-containing anode compound and at least one of a second metal or a metalloid; or a combination thereof.
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Joo, Chul Min
Seong, Baek Cheon
Abstract
A three-dimensional shape measurement apparatus, according to an embodiment, comprises: a projector configured to emit patterned light onto the object; and an imaging device configured to image the object, including an optical system, that includes at least one lens defining an optical axis and a binary phase filter disposed on the optical axis of the optical system so as to transmit light, and configured to form an image by using light that has passed through the at least one lens and the binary phase filter. The binary phase filter may include: a first portion comprising at least one pattern extending circumferentially around the optical axis; and a second portion distinct from the first portion, wherein the first portion and the second portion have different thicknesses in an optical axis direction that is parallel to the optical axis.
G01B 11/25 - Measuring arrangements characterised by the use of optical techniques for measuring contours or curvatures by projecting a pattern, e.g. moiré fringes, on the object
68.
PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF AGING COMPRISING AS ACTIVE INGREDIENT ENGINEERED VIRUS-LIKE PARTICLES COMPRISING OCT4, SOX2, AND KLF4 PROTEINS
RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY (Republic of Korea)
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Kim, Dae Sik
Park, Su Bin
Cho, Sung-Rae
Seo, Jung Hwa
Lee, Siwoo
Abstract
The present invention relates to a pharmaceutical composition for the prevention or treatment of aging, comprising, as an active ingredient, engineered virus-like particles (eVLPs) comprising Oct4, Sox2, and Klf4 proteins. When the eVLPs comprising Oct4, Sox2, and Klf4 proteins, of the present invention, are used, the transient overexpression of Oct4 and Sox2 can be effectively induced, which enables safe induction of overexpression compared to conventional doxycycline-inducible expression methods. Therefore, the eVLPs can be effectively used for the prevention or treatment of aging.
A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
A61P 43/00 - Drugs for specific purposes, not provided for in groups
C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
69.
METHOD AND APPARATUS FOR AUGMENTING DATA OF UWB SIGNAL ON BASIS OF ARTIFICIAL INTELLIGENCE MODEL
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Kim, Taewook
Park, Jungwoon
Yun, Kwan
Abstract
The present disclosure relates to a method for augmenting data of UWB signals on the basis of an artificial intelligence model. The method for augmenting data of UWB signals on the basis of an artificial intelligence model comprises the steps of: receiving a first UWB signal and a second UWB signal; generating a third UWB signal by performing interpolation on the basis of the first UWB signal and the second UWB signal; and providing at least one of the first UWB S signal, the second UWB S signal, and the third UWB S signal to a trained artificial intelligence model, thereby generating a fourth UWB signal having a distribution associated with the at least one signal.
G06N 3/049 - Temporal neural networks, e.g. delay elements, oscillating neurons or pulsed inputs
70.
SEMICONDUCTOR SUBSTRATE FOR POWER SEMICONDUCTOR MANUFACTURING, METHOD OF MANUFACTURING SAME, AND METHOD OF MANUFACTURING POWER SEMICONDUCTOR DEVICE USING SAME
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Kum, Hyun Seong
Ha, Seo Yong
Abstract
An embodiment relates to a semiconductor substrate for power semiconductor manufacturing, a method of manufacturing same, and a method of manufacturing a power semiconductor device using same. The method of manufacturing a semiconductor substrate for power semiconductor manufacturing according to an embodiment may comprise the steps of: preparing an off-cut base substrate; forming a graphene layer and a carbon non-single crystal layer on the base substrate; and separating the graphene layer from the carbon non-single crystal layer. In addition, the semiconductor substrate for power semiconductor manufacturing according to an embodiment may comprise: an off-cut base substrate; and a carbon non-single crystal layer formed on the base substrate.
H01L 21/02 - Manufacture or treatment of semiconductor devices or of parts thereof
H01L 21/78 - Manufacture or treatment of devices consisting of a plurality of solid state components or integrated circuits formed in, or on, a common substrate with subsequent division of the substrate into plural individual devices
H10D 62/83 - Semiconductor bodies, or regions thereof, of devices having potential barriers characterised by the materials being Group IV materials, e.g. B-doped Si or undoped Ge
H10D 48/00 - Individual devices not covered by groups
71.
CATALYSTS EMBEDDED WITH METAL NANOCLUSTERS AND MANUFACTURING METHOD THEREOF
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Hwang, Seong-Ju
Yun, So Yeon
Abstract
According to the present invention, there is provided a method of manufacturing a metal and metal nitride using a single-step nitridation-exsolution synthetic method, including synthesizing metal-substituted metal oxide nanoparticles (S100); synthesizing metal-substituted metal oxide nanowires through hydrothermal synthesis of the metal-substituted metal oxide nanoparticles (S200); and obtaining a metal nitride and exsolved metal through ammonia treatment of the metal-substituted metal oxide nanowires (S300).
C25B 11/081 - Electrodes formed of electrocatalysts on a substrate or carrier characterised by the electrocatalysts material consisting of a single catalytic element or catalytic compound the element being a noble metal
72.
BINDER FOR ALL-SOLID-STATE BATTERY, POSITIVE ELECTRODE FOR ALL-SOLID-STATE BATTERY, AND ALL-SOLID-STATE BATTERY COMPRISING THE SAME
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Kim, Donghyeon
Jung, Yoon Seok
Kim, Youngbok
Song, Min Sang
Kim, Kyu Tae
Kwon, Tae Young
Park, Young Joon
Abstract
A binder for an all-solid-state battery includes a first polymer in which a chain comprising a first hydrogen-bonding functional group is grafted with a side chain on the main chain of a conjugated diene-based polymer and a second polymer in which a chain comprising a second hydrogen-bonding functional group is grafted with a side chain on the main chain of a conjugated diene-based polymer, wherein the first hydrogen-bonding functional group of the first polymer and the second hydrogen-bonding functional group of the second polymer form hydrogen bonds with each other. A positive electrode for an all-solid-state battery including the binder for an all-solid-state battery, a conductive material, a positive electrode active material and a solid electrolyte, and an all-solid-state battery including the positive electrode are also described.
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Pyun, Jae Chul
Abstract
Disclosed are peptides, nucleic acids, recombinant expression vectors, cells, a SARS-CoV-2 vaccine substance, a SARS-CoV vaccine composition, and a SARS-CoV-2 immunization method.
C07K 14/005 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from viruses
C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
A61K 39/215 - Coronaviridae, e.g. avian infectious bronchitis virus
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Kim, Taewook
Park, Jungwoon
Kim, Hyunmin
Abstract
The present disclosure relates to a UWB signal-based object recognition method. The UWB signal-based object recognition method comprises the steps of: receiving a first UWB signal associated with a first object; generating a first sampling signal by performing sampling on the first UWB signal at a first sampling timing on the basis of a sampling window; converting the generated first sampling signal into a first digital signal using an ADC; and providing the converted first digital signal to a trained artificial intelligence model so as to recognize the first object corresponding to the first digital signal.
G01S 13/02 - Systems using reflection of radio waves, e.g. primary radar systemsAnalogous systems
G01S 7/41 - Details of systems according to groups , , of systems according to group using analysis of echo signal for target characterisationTarget signatureTarget cross-section
H03K 5/135 - Arrangements having a single output and transforming input signals into pulses delivered at desired time intervals by the use of time reference signals, e.g. clock signals
G06N 3/0442 - Recurrent networks, e.g. Hopfield networks characterised by memory or gating, e.g. long short-term memory [LSTM] or gated recurrent units [GRU]
G01S 13/34 - Systems for measuring distance only using transmission of continuous waves, whether amplitude-, frequency-, or phase-modulated, or unmodulated using transmission of continuous, frequency-modulated waves while heterodyning the received signal, or a signal derived therefrom, with a locally-generated signal related to the contemporaneously transmitted signal
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Kim, Taewook
Song, Kyoungseok
Abstract
The present disclosure relates to a data modulation method. The data modulation method comprises the steps of: determining data that is a target of data transmission; generating a sync pulse at a first position, which is synchronized with a system clock, and a data pulse at a second position according to the determined data; and performing modulation by using the sync pulse and the data pulse.
H04L 25/49 - Transmitting circuitsReceiving circuits using code conversion at the transmitterTransmitting circuitsReceiving circuits using predistortionTransmitting circuitsReceiving circuits using insertion of idle bits for obtaining a desired frequency spectrumTransmitting circuitsReceiving circuits using three or more amplitude levels
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
JUVIC INC. (Republic of Korea)
TOPADUR PHARMA AG (Switzerland)
Inventor
Jung, Hyungil
Kim, Youseong
Naef, Reto
Atzei, Paola
Francisco, Rita
Abstract
A method for preventing, ameliorating or treating one or more disease or disorders selected from the group consisting of a skin disease, skin aging or steroid-induced skin atrophy, erectile dysfunction, and hair loss, comprises transdermally administering a compound of formula I or a pharmaceutically acceptable salt thereof to a subject in need thereof.
A method for preventing, ameliorating or treating one or more disease or disorders selected from the group consisting of a skin disease, skin aging or steroid-induced skin atrophy, erectile dysfunction, and hair loss, comprises transdermally administering a compound of formula I or a pharmaceutically acceptable salt thereof to a subject in need thereof.
Wherein
R1 is C1-C3alkyl;
R2 is H, CHO or CH═N—OH;
R3 is C1-C4alkyl;
R4 is C1-C6alkyl;
R5 is SO2NR6R7;
wherein R6 and R7 are together with the nitrogen atom to which they are attached form a heterocyclic ring, wherein said heterocyclic ring is selected from piperidine and piperazine, wherein said heterocyclic ring is substituted with at least one R8, and wherein said R8 is independently selected from C1-C6alkyl optionally substituted with OH, ONO2, wherein at least one of said at least one R8 comprises at least one ONO2 moiety.
A61P 17/14 - Drugs for dermatological disorders for baldness or alopecia
77.
INSULATING MANIFOLD FOR ELECTROCHEMICAL REACTIONS WITH EXTERNAL GAS SUPPLY AND ELECTROCHEMICAL REACTION SYSTEM WITHOUT ELECTRICAL CONTACT BETWEEN STACK AND MANIFOLD
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
INDUSTRY ACADEMY COOPERATION FOUNDATION OF SEJONG UNIVERSITY (Republic of Korea)
Inventor
Hong, Jong Sup
Ryu, Dong Hun
Park, Jun Young
Abstract
Disclosed are an insulating manifold for electrochemical reaction configured to receive gas from an external source, and an electrochemical reaction system in which there is no electrical contact between a stack and a manifold. The insulating manifold for the electrochemical reaction includes a plate-shaped base manifold having at least a first fluid conduit and a second fluid conduit extending therethrough vertically; a housing disposed on top of the base manifold and having a vertical wall and an open bottom surface, wherein a lower edge of the housing is coupled to a top of the base manifold; and upper and lower insulating plates respectively defining an upper surface and a lower surface of an inner space defined by the base manifold and the housing.
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Yang, Joon-Sung
Ko, Jae Hyung
Oh, Jun Yong
Abstract
The present disclosure provides an apparatus and method for accelerating activation function, wherein the application range of the activation function is divided into multiple intervals, and an interval indicator is obtained indicating an interval in which an input value is included by using multiple interval detection operators to select one approximate activation function among multiple approximate activation functions approximated in each interval, an approximate activation function being set for the interval designated by the interval indicator is obtained, and the input value is input into the obtained approximate activation function to obtain an activation operation result. According to the apparatus and method for accelerating activation function of of the present disclosure, not only can an interval according to an input value for selecting an approximate activation function be easily determined, but also the operation can be accelerated by performing activation operations simultaneously in parallel.
G06F 17/17 - Function evaluation by approximation methods, e.g. interpolation or extrapolation, smoothing or least mean square method
H03K 19/20 - Logic circuits, i.e. having at least two inputs acting on one outputInverting circuits characterised by logic function, e.g. AND, OR, NOR, NOT circuits
79.
SYSTEM AND METHOD FOR EARLY DIAGNOSIS AND PROGNOSIS PREDICTION OF SEPSIS
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Choi, Jun Kyu
You, Jung Min
Lee, Hyangkyu
Abstract
A system for early diagnosis and prognosis prediction of sepsis, according to an embodiment of the present invention, includes: a memory for storing general blood test data of a patient; and a processor, wherein the processor may be configured to pre-process the general blood test data of the patient stored in the memory as data to be input to an artificial intelligence model, input the pre-processed data to the artificial intelligence model trained for early diagnosis and prognosis prediction of sepsis, and obtain a sepsis prediction result from the artificial intelligence model.
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Pyun, Jae Chul
Abstract
Disclosed are a peptide, a nucleic acid, a recombinant expression vector, a cell, a composition for detecting influenza, and a kit for detecting influenza. The peptide sequence may include CGPVPIRKVDD, CRLRLVLARDF, GDPITSRRLDY, or GTRIALPLRDV The nucleic acid may encode the peptide.
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Kim, Donghyeon
Kim, Ji Young
Song, Min Sang
Jung, Yoon Seok
Kim, Kyu Tae
Park, Young Joon
Abstract
The present invention relates to: a binder for an all-solid-state battery, the binder comprising a main chain crosslinked by a compound including at least two thiol functional groups, wherein the main chain comprises an aromatic vinyl monomer-derived repeating unit and a conjugated diene-based monomer-derived repeating unit; a positive electrode for an all-solid-state battery, the positive electrode comprising the binder for a positive electrode for an all-solid-state battery, a conductive material, a positive electrode active material, and a solid electrolyte; and an all-solid-state battery comprising a positive electrode, a negative electrode, and a solid electrolyte layer disposed between the positive electrode and the negative electrode, wherein the positive electrode includes the positive electrode for an all-solid-state battery.
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Kwon, Ho-Keun
Kim, Gi-Cheon
Abstract
The present invention involves recovering pulmonary inflammation, pulmonary edema or pulmonary capillary vasodilation symptoms caused by infection with viruses, particularly, coronavirus, and furthermore, has the effect of regenerating alveoli, and thus can effectively prevent, ameliorate or treat coronavirus infection or diseases caused by coronavirus infection.
C07K 16/24 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Ham, Bum Sub
Park, Hye Kang
Noh, Jong Youn
Oh, Young Min
Baek, Dong Hyeon
Abstract
An apparatus for calibrating confidence determines a correct logit element and a false logit element among a plurality of logit elements of a logit vector obtained by a neural network model performing a neural network operation on the training data, based on a correct class and a false class determined from a target probability distribution including target probabilities for each of a plurality of classes according to ground truth of the training data as elements, and determines whether to calibrate and a calibration value for a plurality of target probabilities of the target probability distribution based on a difference in value between the correct logit element and the false logit element.
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Chung, Eui-Young
Kim, Do Hyeon
Cho, Min Jung
Lee, Sang Hyup
Eom, Seong Jae
Ahn, Sung Jin
Abstract
Proposed is a method for generating training data for training an artificial intelligence model capable of automatically designing a cache memory structure. The method for generating training data for cache memory design includes setting a reuse profile, setting a first selection reuse distance based on the reuse profile, setting a first load index and a first real reuse distance based on the first selection reuse distance, modifying the reuse profile according to setting the first real reuse distance, and setting a second selection reuse distance based on the modified reuse profile.
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Sohn, Hyun Chul
Kim, Wan Sun
Kim, Ju Sung
Abstract
A material for a switching element, a switching element including the same, and a method for manufacturing the switching element are disclosed. The material for the switching element includes CrTe and has OTS (Ovonic Threshold Switch) switching characteristics.
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Cho, Yong Soo
Jo, Kyeong Su
Kim, Da Bin
Abstract
The present invention relates to a quasi-two-dimensional halide perovskite thin film, in which the halide perovskite has the chemical formula X2An−1BnY3n+1, X is an organic material, A is at least one of methylammonium (MA), formamidinium (FA), and cesium (Cs), B is a metallic cation, Y is a halogen anion, n is a natural number greater than or equal to 2 and less than the natural number k, and as the value of n increases, the piezoelectricity increases.
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Cho, Yong Soo
Park, Kwan Sik
Kim, Da Bin
Abstract
The present invention provides a composite of oxide-based piezoelectric nanoparticles and a halide perovskite, which is prepared from a mixed solution in which the oxide-based piezoelectric nanoparticles are dispersed in an ABX3 halide perovskite solution, A is an organic or inorganic cation, B is a metal cation, and X is a halogen anion. The oxide-based piezoelectric nanoparticles include at least one of PZT, BaTiO3, and Na0.5K0.5NbO3 (NKN). B includes at least one of Pb and Sn. X includes at least one of I, Br, and Cl.
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Park, Hyung Seok
Abstract
Disclosed is a retractor mounting device for a surgery including a mounting unit, a main body provided at an end of the mounting unit, a retraction unit installed to be elevated on the main body, a sub-body disposed to be spaced apart from the main body, and an endoscope unit installed to be movable or rotatable on the sub-body.
A61B 1/32 - Devices for opening or enlarging the visual field, e.g. of a tube of the body
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
89.
Apparatus for Controlling Vehicle and Method Thereof
UIF (University Industry Foundation),Yonsei University (Republic of Korea)
Inventor
Kim, Seong Hwan
Choi, Jongeun
Cho, Taek Hyung
Abstract
A vehicle control apparatus may comprise sensors obtaining raw data identifying an external object, stored neural network models, decoders, and a processor. The processor may analyze the raw data from each sensor for predicting object locations and type using neural network models and decoders. The processor may select input data based on a distance between the object locations and reliability values and enter the selected input data into an additional neural network model of the neural network models. The processor may output, based on the input data entered into the additional neural network model, data comprising a final object location or type, and control, based on the output data, operation of the vehicle.
G06T 7/70 - Determining position or orientation of objects or cameras
G06V 10/77 - Processing image or video features in feature spacesArrangements for image or video recognition or understanding using pattern recognition or machine learning using data integration or data reduction, e.g. principal component analysis [PCA] or independent component analysis [ICA] or self-organising maps [SOM]Blind source separation
G06V 10/774 - Generating sets of training patternsBootstrap methods, e.g. bagging or boosting
G06V 10/80 - Fusion, i.e. combining data from various sources at the sensor level, preprocessing level, feature extraction level or classification level
G06V 10/82 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using neural networks
G06V 20/56 - Context or environment of the image exterior to a vehicle by using sensors mounted on the vehicle
90.
TRIPLE COMBINATION DRUG DOSING THERAPY FOR HEAD AND NECK CANCER TREATMENT
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Sung, Young Chul
Woo, Jung Won
Kim, Hye Ryun
Hong, Min Hee
Kim, Chang Gon
Abstract
A triple combination drug dosing therapy for head and neck cancer treatment is disclosed. More specifically, a therapeutic method for the treatment of head and neck cancer by dosing an anti-PD1 antibody, a human papilloma virus (HPV) vaccine, and a long-lasting recombinant IL-7 fusion protein are disclosed. The triple combination drug dosing therapy exhibits a remarkable effect in the treatment of intractable head and neck cancer that has been difficult to treat with existing therapeutic agents.
C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
A61K 9/00 - Medicinal preparations characterised by special physical form
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Pyun, Jae Chul
Abstract
Disclosed are a peptide, an antibody or an antigen-binding fragment thereof, a nucleic acid, a recombinant expression vector, a cell, a substance for detecting porcine epidemic diarrhea virus, a one-step diagnostic kit for porcine epidemic diarrhea, and a one-step diagnostic method for porcine epidemic diarrhea. Disclosed are a peptide, an antibody or an antigen-binding fragment thereof, a nucleic acid, a recombinant expression vector, a cell, a substance for detecting SARS-CoV-2 nucleoprotein, a one-step SARS-CoV-2 diagnostic kit, and a one-step SARS-CoV-2 diagnostic method.
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Yeon, Pyungwoo
Kim, Mingu
Abstract
Disclosed is an automated and wireless accelerated heat treat life testing system, and the system includes a readout coil; and an LC sensor on the readout coil, wherein the LC sensor includes: a sensing coil; an IDC sensor on the sensing coil; and a humidity sensing layer on a sensing area of the IDC sensor.
G01M 3/16 - Investigating fluid tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using electric detection means
G01N 27/22 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating capacitance
93.
PULSE SIGNAL GENERATOR TO REDUCE POWER CONSUMPTION OF SRAM AND SRAM HAVING THE SAME
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Jung, Seong Ook
Yei, Seung Jae
Cho, Keon Hee
Yeo, Min June
Abstract
The present disclosure provides a pulse signal generator capable of reducing power consumption by varying the width of a word line signal depending on temperature, including a delay unit which receives a clock signal, delays the signal, and outputs a delayed clock signal while adjusting the delay time of the delayed clock signal depending on temperature, and a pulse generation circuit which receives a clock signal and a delayed clock signal, whose delay time is adjusted depending on temperature, and logically combines them to generate a pulse signal having a pulse width that varies depending on temperature, and an SRAM having the same.
G11C 11/412 - Digital stores characterised by the use of particular electric or magnetic storage elementsStorage elements therefor using electric elements using semiconductor devices using transistors forming cells with positive feedback, i.e. cells not needing refreshing or charge regeneration, e.g. bistable multivibrator or Schmitt trigger using field-effect transistors only
H03K 5/00 - Manipulation of pulses not covered by one of the other main groups of this subclass
H03K 5/134 - Arrangements having a single output and transforming input signals into pulses delivered at desired time intervals using a chain of active-delay devices with field-effect transistors
H03K 19/20 - Logic circuits, i.e. having at least two inputs acting on one outputInverting circuits characterised by logic function, e.g. AND, OR, NOR, NOT circuits
94.
FABRICATION METHOD OF DIRECTIONAL TISSUE WITH ACOUSTIC PATTERNING OF PORE- FORMING PARTICLES
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Lee, Hyung Suk
Lee, Yu Nam
Kang, Byung Jun
Rhyou, Chan Ryeol
Abstract
Disclosed is a method of applying a three-dimensional acoustic wave to cells and pore-forming particles similar in size to cells contained in a hydrogel to perform the micro-sized patterning thereof, and then melting the particles to form pores in which the tissue is rapidly cultured and is regenerated.
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Cheon, Keun Ah
Park, Yu Rang
Abstract
Disclosed is an electronic device for screening autism spectrum disorder (ASD) and ASD symptom severity based on a retina image including an input unit that receives the retina image, a classification model that classifies whether there is the ASD, and the ASD symptom severity based on the retina image by using a deep learning algorithm, and at least one processor that controls the input unit and the classification model. The at least one processor is configured to preprocess the received retina image, to train the classification model such that the classification model classifies the ASD and typical development (TD) by using the preprocessed retina image, and classifies the ASD symptom severity, and to allow the trained classification model to screen whether there is the ASD and the ASD symptom severity depending on the input retina image.
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Kim, Seong Hwan
Choi, Jongeun
Cho, Taek Hyung
Abstract
A vehicle control apparatus includes a first sensor, a second sensor, a processor, and a memory storing first and second neural network models. The processor is configured to obtain first object data for predicting information related to the external object based on entering the first sensor data into the first neural network model, obtain second object data for predicting information related to the external object based on entering the second sensor data into the first neural network model the first object data or the second object data as input data to be entered into the second neural network model, and output data including a final location of the external object or a final type of the external object based on entering the input data into the second neural network model.
G06T 7/70 - Determining position or orientation of objects or cameras
G06V 10/764 - Arrangements for image or video recognition or understanding using pattern recognition or machine learning using classification, e.g. of video objects
G06V 20/56 - Context or environment of the image exterior to a vehicle by using sensors mounted on the vehicle
97.
DATABASE TUNING METHOD USING DEEP GENETIC ALGORITHM
UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY (Republic of Korea)
Inventor
Park, Sang Hyun
Jun, Jinhui
Lee, Ji Eun
Abstract
The present embodiments provide a database tuning method capable of improving database performance by defining a new expression for a workload to find the most similar workload in a database, applying a genetic algorithm to a combined workload, and deriving an optimized parameter through deep learning.
UIF UNIVERSITY INDUSTRY FOUNDATION YONESI UNIVERSITY (Republic of Korea)
JUVIC INC. (Republic of Korea)
Inventor
Jung, Hyungil
Yang, Huisuk
Kang, Geonwoo
Abstract
The present invention relates to a soluble microneedle for local anesthesia and a local anesthesia patch comprising same, the soluble microneedle comprising an amide-based local anesthetic, hyaluronic acid, and polyvinylpyrrolidone in a specific content ratio. The present invention uses the soluble microneedle to implement direct drug delivery by physically permeating through the stratum corneum and mucosa, and thus a precise and rapid anesthetic effect may be exhibited. Especially, the microneedle comprising a specific amount of polyvinylpyrrolidone is dissolved, and the anesthetic contained in the microneedle is rapidly delivered to nerve cells, and thus the disadvantage of a long waiting time of conventional anesthetic creams may be overcome, and thus the present invention has the advantage of being usable in various ways in dental, dermatology, and other surgical procedures requiring local anesthesia.
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 31/167 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
A61K 47/36 - PolysaccharidesDerivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Chung, Eui-Young
Choi, Duheon
Jeong, Taeyang
Abstract
The present disclosure discloses a method and an apparatus of translating a virtual address for processing-in-memory. The virtual address translating method of the present disclosure includes determining a data operand for processing-in-memory to be shared with a processor-in-memory, by a CPU, searching a page table corresponding to the data operand from a memory, defining an address space of the determined data operand in an operand address space which is divided into a plurality of sub spaces and generating an operand page table according to the defined address space, by the CPU, and determining a physical address for the determined data operand, using the operand page table, by the processor-in-memory.
UIF (University Industry Foundation), Yonsei University (Republic of Korea)
Inventor
Jeon, Jaemin
Hwang, Soonkyu
Park, No-Cheol
Kim, Tano
Han, Wanhee
Park, Seongjin
Lee, Haegu
Abstract
An inspection method is provided.
An inspection method is provided.
The inspection method includes obtaining a plurality of vision images in a surface of a semiconductor device at a latitude and a longitude where a plurality of illuminations are designated, obtaining a bidirectional reflectance distribution function (BRDF) on the surface of the semiconductor device by using the obtained plurality of vision images, rendering a vision image of the semiconductor device at a latitude and a longitude where the plurality of illuminations are not designated, based on the obtained BRDF, performing a two-dimensional (2D) Fourier transform on a synthesis image of the rendered image and the obtained plurality of vision images to calculate a power spectrum density, selecting an integral section of the power spectrum density, and performing an integral on the power spectrum density in the integral section to quantify roughness.