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1.
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FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF
Application Number |
US2024027190 |
Publication Number |
2025/128149 |
Status |
In Force |
Filing Date |
2024-05-01 |
Publication Date |
2025-06-19 |
Owner |
VIEWPOINT MOLECULAR TARGETING, INC. (USA)
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Inventor |
- Schultz, Michael K.
- Li, Mengshi
- Cagle, Brianna S.
- Baumhover, Nicholas
- Vance, Ivy
- Liu, Dijie
- Rodman, Samuel
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Abstract
The present invention relates to a fibroblast activation protein alpha (FAP)-targeting conjugate comprising Formula I: Y-L-X, wherein Y is a chelator or cytotoxic drug, L is a linker, and X is a molecule comprising a cyclic peptide of formula A-[Z-AA1-AA2-AA3-AA4-AA5-AA6-AA7-Z]-B. A is N-terminal structure. B is C-terminal structure, and each of the Z, AA1, AA2, AA3, AA4, AA5, AA6, AA7 is a residue of an amino acid.
IPC Classes ?
- A61K 47/64 - Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K 51/08 - Peptides, e.g. proteins
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2.
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SYSTEMS AND METHODS FOR GENERATING RADIONUCLIDES
Application Number |
US2023069474 |
Publication Number |
2024/050168 |
Status |
In Force |
Filing Date |
2023-06-30 |
Publication Date |
2024-03-07 |
Owner |
VIEWPOINT MOLECULAR TARGETING, INC. (USA)
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Inventor |
- Sagastume, Edwin A.
- Schultz, Michael K.
- Mcalister, Daniel
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Abstract
Systems and methods for generating radionuclides, such as radium-224. Systems herein may include a first cartridge having a first opening, a second opening, and a chamber therebetween having a first resin having affinity for thorium-228 and bismuth-212; a second cartridge having a first opening, a second opening, and a chamber therebetween having a second resin having affinity for thorium-228 and bismuth-212, a third cartridge having a first opening, a second opening, and a chamber therebetween comprising a third resin having affinity for thorium-228 and bismuth-212, a fourth cartridge having a first opening, a second opening, and a chamber therebetween having a third resin having affinity for lead-212; wherein a continuous flow path is formed from a top of the first cartridge though the second cartridge, through the third cartridge, and to a bottom of the fourth cartridge during system use.
IPC Classes ?
- B01J 20/285 - Porous sorbents based on polymers
- B01D 15/10 - Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D 15/18 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- C22B 3/42 - Treatment or purification of solutions, e.g. obtained by leaching by ion-exchange extraction
- C01F 15/00 - Compounds of thorium
- C01G 21/00 - Compounds of lead
- C01G 29/00 - Compounds of bismuth
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3.
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VIEWPOINT MOLECULAR TARGETING
Serial Number |
90059183 |
Status |
Registered |
Filing Date |
2020-07-17 |
Registration Date |
2021-05-18 |
Owner |
Viewpoint Molecular Targeting, Inc., DBA Viewpoint Molecular Targeting ()
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NICE Classes ? |
05 - Pharmaceutical, veterinary and sanitary products
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Goods & Services
Isotopes for medical purposes; radioactive pharmaceutical preparations for use in vivo diagnostic or therapeutic use
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