Native Microbials, Inc.

United States of America

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        United States 51
        World 6
        Canada 5
Date
2025 February 1
2025 (YTD) 1
2024 6
2023 6
2022 12
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IPC Class
A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms 38
A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants 29
A61K 35/74 - Bacteria 27
C12N 1/20 - BacteriaCulture media therefor 25
A61K 35/741 - Probiotics 20
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Status
Pending 22
Registered / In Force 40

1.

METHODS OF IMPROVING DESIRABLE TRAITS IN FOWL

      
Application Number 18442348
Status Pending
Filing Date 2024-02-15
First Publication Date 2025-02-13
Owner Native Microbials, Inc. (USA)
Inventor
  • Embree, Mallory
  • Gogul, Grant
  • Martino, Cameron
  • Pitt, Norman

Abstract

The disclosure relates to methods for decreasing feed conversion ratios in fowl through administering isolated microorganisms to the fowl. In particular aspects, the disclosure provides methods of decreasing feed conversion ratios in fowl through administration of a Bacillus sp. to the fowl. The disclosure further relates to isolated microorganisms and compositions comprising the same.

IPC Classes  ?

  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A01K 45/00 - Other aviculture appliances, e.g. devices for determining whether a bird is about to lay
  • A23K 40/30 - Shaping or working-up of animal feeding-stuffs by encapsulatingShaping or working-up of animal feeding-stuffs by coating
  • A23K 50/75 - Feeding-stuffs specially adapted for particular animals for birds for poultry
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 35/00 - Medicinal preparations containing materials or reaction products thereof with undetermined constitution
  • A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
  • A61K 35/747 - Lactobacilli, e.g. L. acidophilus or L. brevis
  • C12N 1/20 - BacteriaCulture media therefor
  • C12R 1/225 - Lactobacillus

2.

RUMINANT COMPOSITIONS

      
Application Number 18394616
Status Pending
Filing Date 2023-12-22
First Publication Date 2024-11-28
Owner Native Microbials, Inc. (USA)
Inventor
  • Embree, Mallory
  • Picking, Luke
  • Gogul, Grant
  • Tarasova, Janna

Abstract

The disclosure relates to compositions beneficial for ruminant administration. Particularly, the disclosure provides compositions formulated for ruminants that comprise beneficial microbes.

IPC Classes  ?

  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
  • A23K 10/37 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms from waste material
  • A23K 20/158 - Fatty acidsFatsProducts containing oils or fats
  • A23K 20/163 - SugarsPolysaccharides
  • A23K 20/28 - Silicates, e.g. perlites, zeolites or bentonites
  • A23K 40/35 - Making capsules specially adapted for ruminants
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A23L 31/10 - Yeasts or derivatives thereof
  • A23L 33/135 - Bacteria or derivatives thereof, e.g. probiotics
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 35/74 - Bacteria
  • A61K 35/741 - Probiotics
  • A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
  • A61K 35/748 - Cyanobacteria, i.e. blue-green bacteria or blue-green algae, e.g. spirulina
  • A61K 36/06 - Fungi, e.g. yeasts
  • A61K 36/062 - Ascomycota
  • A61K 36/064 - Saccharomycetales, e.g. baker's yeast
  • A61K 39/02 - Bacterial antigens
  • A61P 15/04 - Drugs for genital or sexual disordersContraceptives for inducing labour or abortionUterotonics
  • A61P 31/04 - Antibacterial agents
  • C12N 1/14 - Fungi Culture media therefor
  • C12N 1/20 - BacteriaCulture media therefor

3.

MICROBIAL COMPOSITIONS AND METHODS FOR RUMINANT HEALTH AND PERFORMANCE

      
Application Number 18524351
Status Pending
Filing Date 2023-11-30
First Publication Date 2024-11-07
Owner Native Microbials, Inc. (USA)
Inventor
  • Embree, Mallory
  • Martino, Cameron
  • Pitt, Norman
  • Embree, Jordan
  • Dodge, Corey

Abstract

The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial compositions, and compositions comprising the same, in methods for modulating the agricultural production of ruminants. In particular aspects, the disclosure provides methods of increasing feed efficiency, and methods of decreasing acidosis.

IPC Classes  ?

  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A61K 35/74 - Bacteria
  • A61P 1/04 - Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

4.

COMPOSITIONS AND METHODS FOR REDUCING ENTERIC METHANE EMISSION IN RUMINANTS

      
Application Number US2024027326
Publication Number 2024/229172
Status In Force
Filing Date 2024-05-01
Publication Date 2024-11-07
Owner NATIVE MICROBIALS, INC. (USA)
Inventor
  • Embree, Mallory
  • Marotz, Clarisse A.
  • Lefler, Joshua
  • Calapa, Kayla
  • Gaffney, James

Abstract

The present disclosure teaches methods of utilizing isolated microorganisms, microbial ensembles, and compositions for improving feed efficiency and reducing enteric methane emissions in cattle. The disclosure also provides a method of quantifying enteric methane emissions in cattle at commercial scale.

IPC Classes  ?

  • A23K 10/16 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants

5.

COMPOSITIONS AND METHODS FOR IMPROVING MILK YIELD AND MILK COMPOSITIONAL CHARACTERISTICS IN RUMINANTS

      
Application Number 18556632
Status Pending
Filing Date 2022-04-22
First Publication Date 2024-06-27
Owner Native Microbials, Inc. (USA)
Inventor Embree, Mallory

Abstract

The disclosure relates to isolated microorganisms, microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial ensembles, and compositions comprising the same, in methods for modulating the production and yield of milk and milk components in ruminants. In particular aspects, the disclosure provides methods of increasing desirable components of milk in ruminants.

IPC Classes  ?

  • A61K 35/741 - Probiotics
  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 35/00 - Medicinal preparations containing materials or reaction products thereof with undetermined constitution
  • A61P 15/14 - Drugs for genital or sexual disordersContraceptives for lactation disorders, e.g. galactorrhoea

6.

MICROBIAL COMPOSITIONS AND METHODS OF USE FOR IMPROVING MILK PRODUCTION

      
Application Number 18394679
Status Pending
Filing Date 2023-12-22
First Publication Date 2024-04-18
Owner Native Microbials, Inc. (USA)
Inventor
  • Embree, Mallory
  • Picking, Luke
  • Gogul, Grant
  • Tarasova, Janna

Abstract

The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial consortia, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial consortia, and compositions comprising the same, in methods for modulating the production and yield of milk and milk components in ruminants. In particular aspects, the disclosure provides methods of increasing desirable components of milk in ruminants. Furthermore, the disclosure provides for methods of modulating the rumen microbiome.

IPC Classes  ?

  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
  • A23K 10/37 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms from waste material
  • A23K 20/158 - Fatty acidsFatsProducts containing oils or fats
  • A23K 20/163 - SugarsPolysaccharides
  • A23K 20/28 - Silicates, e.g. perlites, zeolites or bentonites
  • A23K 40/35 - Making capsules specially adapted for ruminants
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A23L 31/10 - Yeasts or derivatives thereof
  • A23L 33/135 - Bacteria or derivatives thereof, e.g. probiotics
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 35/74 - Bacteria
  • A61K 35/741 - Probiotics
  • A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
  • A61K 36/06 - Fungi, e.g. yeasts
  • A61K 36/062 - Ascomycota
  • A61K 36/064 - Saccharomycetales, e.g. baker's yeast
  • A61K 39/02 - Bacterial antigens
  • A61P 15/04 - Drugs for genital or sexual disordersContraceptives for inducing labour or abortionUterotonics
  • A61P 31/04 - Antibacterial agents
  • C12N 1/14 - Fungi Culture media therefor
  • C12N 1/20 - BacteriaCulture media therefor

7.

MICROBIAL COMPOSITIONS FOR FOWL HEALTH AND PERFORMANCE

      
Application Number 18477766
Status Pending
Filing Date 2023-09-29
First Publication Date 2024-01-25
Owner Native Microbials, Inc. (USA)
Inventor
  • Embree, Mallory
  • Gogul, Grant
  • Martino, Cameron
  • Pitt, Norman

Abstract

The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial ensembles, and compositions comprising the same, in methods for modulating the production of poultry, disease resistance, and egg yield. In particular aspects, the disclosure provides methods of increasing feed efficiency, and methods of preventing colonization of pathogenic microbes.

IPC Classes  ?

  • A23K 50/75 - Feeding-stuffs specially adapted for particular animals for birds for poultry
  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • C12N 1/20 - BacteriaCulture media therefor
  • A61K 35/741 - Probiotics
  • C12N 1/14 - Fungi Culture media therefor

8.

VARYS

      
Serial Number 98306054
Status Pending
Filing Date 2023-12-08
Owner Native Microbials, Inc. ()
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Therapeutic microbial feed additives for use as nutritional supplements for cattle; nutritional microbial feed additives for use as nutritional supplements for cattle

9.

METHODS FOR SUPPORTING GRAIN INTENSIVE DIETS IN RUMINANTS WITH ADMINISTRATION OF CHORDICOCCUS SP.

      
Application Number 18031936
Status Pending
Filing Date 2021-10-15
First Publication Date 2023-11-30
Owner Native Microbials, Inc. (USA)
Inventor
  • Embree, Mallory
  • Gaffney, James
  • Gilmore, Sean
  • Embree, Jordan

Abstract

The disclosure relates to a novel microbial genus Chordicoccus—and a type strain of the genus, Chordicoccus furentiruminis—along with compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganism, in methods for modulating the agricultural production of ruminants. In particular aspects, the disclosure provides methods of increasing feed efficiency and methods of decreasing acidosis.

IPC Classes  ?

  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A23K 40/30 - Shaping or working-up of animal feeding-stuffs by encapsulatingShaping or working-up of animal feeding-stuffs by coating
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants

10.

SYSTEMS, DEVICES, AND METHODS FOR RUMINANT ACIDOSIS DETECTION

      
Application Number US2023066851
Publication Number 2023/220656
Status In Force
Filing Date 2023-05-10
Publication Date 2023-11-16
Owner NATIVE MICROBIALS, INC. (USA)
Inventor Embree, Mallory

Abstract

Embodiments include example systems, devices, and methods for solvent analysis and biological sample analysis, and for analyzing biological samples for solvents associated with health status related to ruminant acidosis, and for on-farm identification of acidosis in ruminants. In certain aspects, acidosis is detected via measurement of solvents and other volatile chemicals present in the ruminants. Embodiments include methods and systems of diagnosing a state of health of an animal by receiving a sample of a bodily fluid or gas from an oral or nasal cavity of the animal, measuring a quantity of at least one of an identified solvent or an identified gas in the sample, and determining a state of health associated with the animal based on the quantity of the identified solvent.

IPC Classes  ?

  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A23K 10/16 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions

11.

IMPROVING MILK PRODUCTION AND COMPOSITIONAL CHARACTERISTICS WITH NOVEL RUMINOCOCCUS BOVIS

      
Application Number 17916432
Status Pending
Filing Date 2021-03-31
First Publication Date 2023-05-04
Owner Native Microbials, Inc. (USA)
Inventor
  • Embree, Mallory
  • Embree, Jordan
  • Gilmore, Sean

Abstract

The disclosure relates to isolated microorganisms—including novel strains of the microorganisms such as Ruminococcus bovis sp. nov.—microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial ensembles, and compositions comprising the same, in methods for modulating the production and yield of milk and milk components in ruminants. In particular aspects, the disclosure provides methods of increasing desirable components of milk in ruminants. Furthermore, the disclosure provides for methods of modulating the rumen microbiome.

IPC Classes  ?

  • A61K 35/74 - Bacteria
  • A61K 36/064 - Saccharomycetales, e.g. baker's yeast
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
  • A23K 40/35 - Making capsules specially adapted for ruminants

12.

MEGENTIUM

      
Serial Number 97912123
Status Pending
Filing Date 2023-04-28
Owner Native Microbials, Inc. ()
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Nutritional supplements for canines; therapeutic feed supplements for canines; cultures of microorganisms for veterinary use, namely, use as a nutritional supplement for canines; cultures of microorganisms for veterinary use, namely, use as a nutritional therapeutic supplement for canines

13.

CLOMEGENT

      
Serial Number 97912126
Status Pending
Filing Date 2023-04-28
Owner Native Microbials, Inc. ()
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Nutritional feed supplements for canines to aid digestion; therapeutic feed supplements for canines to aid digestion; cultures of microorganisms for veterinary use, namely, use as a nutritional supplement for canines to aid digestion; cultures of microorganisms for veterinary use, namely, use as a nutritional therapeutic supplement for canines to aid digestion

14.

Microbial compositions and methods for ruminant health and performance

      
Application Number 17354306
Grant Number 11871767
Status In Force
Filing Date 2021-06-22
First Publication Date 2022-12-08
Grant Date 2024-01-16
Owner Native Microbials, Inc. (USA)
Inventor
  • Embree, Mallory
  • Martino, Cameron
  • Pitt, Norman
  • Embree, Jordan
  • Dodge, Corey

Abstract

The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial compositions, and compositions comprising the same, in methods for modulating the agricultural production of ruminants. In particular aspects, the disclosure provides methods of increasing feed efficiency, and methods of decreasing acidosis.

IPC Classes  ?

  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A61K 35/74 - Bacteria
  • A61P 1/04 - Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants

15.

Microbial compositions and methods of use for canine enteropathy and dysbiosis

      
Application Number 17818834
Grant Number 12180464
Status In Force
Filing Date 2022-08-10
First Publication Date 2022-12-08
Grant Date 2024-12-31
Owner Native Microbials, Inc. (USA)
Inventor
  • Embree, Mallory
  • Gogul, Grant
  • Yang, Fan

Abstract

The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial compositions, and compositions comprising the same, in methods for treating or preventing gastrointestinal enteropathy or dysbiosis in canines. In particular aspects, the disclosure provides methods of treating or preventing morbidity and mortality caused by GI pathogenesis or autoimmunity.

IPC Classes  ?

  • C12N 1/20 - BacteriaCulture media therefor
  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A23K 20/163 - SugarsPolysaccharides
  • A23K 20/174 - Vitamins
  • A23K 40/30 - Shaping or working-up of animal feeding-stuffs by encapsulatingShaping or working-up of animal feeding-stuffs by coating
  • A23K 50/42 - Dry feed
  • A23K 50/48 - Moist feed
  • A61P 1/12 - Antidiarrhoeals

16.

COMPOSITIONS AND METHODS FOR IMPROVING MILK YIELD AND MILK COMPOSITIONAL CHARACTERISTICS IN RUMINANTS

      
Application Number US2022026037
Publication Number 2022/226367
Status In Force
Filing Date 2022-04-22
Publication Date 2022-10-27
Owner NATIVE MICROBIALS, INC. (USA)
Inventor Embree, Mallory

Abstract

The disclosure relates to isolated microorganisms, microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial ensembles, and compositions comprising the same, in methods for modulating the production and yield of milk and milk components in ruminants. In particular aspects, the disclosure provides methods of increasing desirable components of milk in ruminants.

IPC Classes  ?

  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A61K 35/74 - Bacteria
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants

17.

ARKUS DAILY

      
Serial Number 97600635
Status Registered
Filing Date 2022-09-21
Registration Date 2023-10-24
Owner Native Microbials, Inc. ()
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Nutritional supplements for canines; nutritional additives for feed or water for canines for use as a nutritional supplement; microbial products for canines, namely, cultures of micro-organisms to aid digestion, for use as a nutritional supplement

18.

Microbial compositions and methods of use for improving milk production

      
Application Number 17678634
Grant Number 11910809
Status In Force
Filing Date 2022-02-23
First Publication Date 2022-09-15
Grant Date 2024-02-27
Owner Native Microbials, Inc. (USA)
Inventor
  • Embree, Mallory
  • Picking, Luke
  • Gogul, Grant
  • Tarasova, Janna

Abstract

The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial consortia, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial consortia, and compositions comprising the same, in methods for modulating the production and yield of milk and milk components in ruminants. In particular aspects, the disclosure provides methods of increasing desirable components of milk in ruminants. Furthermore, the disclosure provides for methods of modulating the rumen microbiome.

IPC Classes  ?

  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A61K 36/062 - Ascomycota
  • A61P 15/04 - Drugs for genital or sexual disordersContraceptives for inducing labour or abortionUterotonics
  • A61K 35/74 - Bacteria
  • A61K 36/06 - Fungi, e.g. yeasts
  • A61K 36/064 - Saccharomycetales, e.g. baker's yeast
  • A23K 40/35 - Making capsules specially adapted for ruminants
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
  • A23L 31/10 - Yeasts or derivatives thereof
  • A23L 33/135 - Bacteria or derivatives thereof, e.g. probiotics
  • A61P 31/04 - Antibacterial agents
  • A61K 35/741 - Probiotics
  • A61K 39/02 - Bacterial antigens
  • C12N 1/14 - Fungi Culture media therefor
  • C12N 1/20 - BacteriaCulture media therefor
  • A23K 20/158 - Fatty acidsFatsProducts containing oils or fats
  • A23K 20/163 - SugarsPolysaccharides
  • A23K 20/28 - Silicates, e.g. perlites, zeolites or bentonites
  • A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
  • A23K 10/37 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms from waste material
  • A61K 35/748 - Cyanobacteria, i.e. blue-green bacteria or blue-green algae, e.g. spirulina

19.

COMPOSITIONS AND METHODS FOR BROILER HEALTH AND PERFORMANCE

      
Application Number 17627289
Status Pending
Filing Date 2020-07-15
First Publication Date 2022-08-25
Owner Native Microbials, Inc. (USA)
Inventor
  • Embree, Mallory
  • Gogul, Grant
  • Martino, Cameron
  • Pitt, Norm
  • Bolek, Kevin

Abstract

The disclosure relates to compositions and methods for improving broiler health and performance. Specifically, the disclosure provides compositions comprising one or more bacteria that can be administered to broilers to increase feed efficiency, weight gain, and immunity, and reduce or prevent inflammation, mortality, and/or the colonization of pathogenic microbes.

IPC Classes  ?

  • A61K 35/741 - Probiotics
  • A61P 31/04 - Antibacterial agents
  • A23K 50/75 - Feeding-stuffs specially adapted for particular animals for birds for poultry
  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms

20.

AVIUS

      
Serial Number 97563524
Status Registered
Filing Date 2022-08-24
Registration Date 2025-03-04
Owner Native Microbials, Inc. ()
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Nutritional supplements for poultry; poultry feed additives for use as a nutritional supplement; nutritional additives for feed or water for poultry for use as a nutritional supplement; microbial products for poultry, namely, cultures of micro-organisms to aid digestion, for use as a nutritional supplement

21.

METHODS FOR IMPROVING TREATMENT OF EQUINE COLIC BY ADMINISTRATION OF A SYNTHETIC BIOENSEMBLE OR PURIFIED STRAINS THEREOF

      
Application Number 17609138
Status Pending
Filing Date 2020-05-06
First Publication Date 2022-07-14
Owner Native Microbials, Inc. (USA)
Inventor
  • Embree, Mallory
  • Martino, Cameron
  • Yang, Fan
  • Embree, Jordan
  • Gaffney, James

Abstract

The disclosure relates to isolated microorganisms, including novel strains of the microorganisms, synthetic bioensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, synthetic bioensembles, and compositions comprising the same, in methods for modulating the health of equine animals In particular aspects, the disclosure provides methods of treating and/or preventing colic and shifting the gut microbiome.

IPC Classes  ?

  • A61K 35/744 - Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
  • A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
  • A61K 35/741 - Probiotics
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • A61P 1/14 - Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

22.

METHODS AND SYSTEMS FOR STABILIZATION AND PRESERVATION OF MICROBES

      
Application Number 17602317
Status Pending
Filing Date 2020-04-09
First Publication Date 2022-06-23
Owner Native Microbials, Inc. (USA)
Inventor
  • Dodge, Corey
  • La, Rich
  • Taylor, Adam
  • Green, Howard
  • Radakovich, Gina
  • Gilmore, Sean

Abstract

The present disclosure relates to methods of stabilization of microbial compositions comprising combining a population of pre-served microbial cells with at least one water activity scavenger (WAS) to a desired homogeneity level; and packaging and sealing the mixture of preserved microbial cells and the WAS. The present disclosure further relates to the stabilized microbial compositions and uses thereof.

IPC Classes  ?

  • C12N 1/04 - Preserving or maintaining viable microorganisms
  • C12N 1/14 - Fungi Culture media therefor
  • C12N 1/20 - BacteriaCulture media therefor

23.

Fowl production by administration of a synthetic bioensemble of microbes or purified strains thereof

      
Application Number 16757336
Grant Number 11825862
Status In Force
Filing Date 2018-10-18
First Publication Date 2022-06-09
Grant Date 2023-11-28
Owner Native Microbials, Inc. (USA)
Inventor
  • Embree, Mallory
  • Gogul, Grant
  • Martino, Cameron
  • Pitt, Norm

Abstract

The disclosure relates to isolated microorganisms-including novel strains of the microorganisms-microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial ensembles, and compositions comprising the same, in methods for modulating the production of poultry, disease resistance, and egg yield. In particular aspects, the disclosure provides methods of increasing feed efficiency, and methods of preventing colonization of pathogenic microbes.

IPC Classes  ?

  • A23K 50/75 - Feeding-stuffs specially adapted for particular animals for birds for poultry
  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • C12N 1/20 - BacteriaCulture media therefor
  • A61K 35/741 - Probiotics
  • C12N 1/14 - Fungi Culture media therefor

24.

METHODS, APPARATUSES, AND SYSTEMS FOR IMPROVING MICROBIAL PRESERVATION YIELD THROUGH RESCUE AND SERIAL PASSAGE OF PRESERVED CELLS

      
Application Number 17434529
Status Pending
Filing Date 2020-02-28
First Publication Date 2022-05-05
Owner Native Microbials, Inc. (USA)
Inventor
  • Gilmore, Sean
  • Dodge, Corey

Abstract

The present disclosure provides methods of improving microbe viability after preservation comprising subjecting a population of target microbial cells to one or more preservation challenges and preparing a product using the population of preserved viability-enhanced microbial cells produced from said methods. The present disclosure further provides products comprising preserved viability-enhanced microbial cells produced by the methods described herein.

IPC Classes  ?

25.

METHODS FOR SUPPORTING GRAIN INTENSIVE DIETS IN RUMINANTS WITH ADMINISTRATION OF CHORDICOCCUS SP.

      
Application Number US2021055210
Publication Number 2022/081992
Status In Force
Filing Date 2021-10-15
Publication Date 2022-04-21
Owner NATIVE MICROBIALS, INC. (USA)
Inventor
  • Embree, Mallory
  • Gaffney, James
  • Gilmore, Sean
  • Embree, Jordan

Abstract

ChordicoccusChordicoccus furentiruminisChordicoccus furentiruminis—along with compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganism, in methods for modulating the agricultural production of ruminants. In particular aspects, the disclosure provides methods of increasing feed efficiency and methods of decreasing acidosis.

IPC Classes  ?

  • A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
  • A23K 1/00 - Animal feeding-stuffs
  • A23K 1/16 - supplemented with accessory food factors; Salt blocks
  • A23K 10/16 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions

26.

IMPROVING MILK PRODUCTION AND COMPOSITIONAL CHARACTERISTICS WITH NOVEL RUMINOCOCCUS BOVIS

      
Application Number US2021025264
Publication Number 2021/202804
Status In Force
Filing Date 2021-03-31
Publication Date 2021-10-07
Owner NATIVE MICROBIALS, INC. (USA)
Inventor
  • Embree, Mallory
  • Embree, Jordan
  • Gilmore, Sean

Abstract

Ruminococcus bovis sp. nov.Ruminococcus bovis sp. nov.—microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial ensembles, and compositions comprising the same, in methods for modulating the production and yield of milk and milk components in ruminants. In particular aspects, the disclosure provides methods of increasing desirable components of milk in ruminants. Furthermore, the disclosure provides for methods of modulating the rumen microbiome.

IPC Classes  ?

  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A61K 35/74 - Bacteria

27.

MICROBIAL COMPOSITIONS AND METHODS OF USE FOR CANINE ENTEROPATHY AND DYSBIOSIS

      
Document Number 03166211
Status Pending
Filing Date 2021-02-10
Open to Public Date 2021-08-19
Owner NATIVE MICROBIALS, INC. (USA)
Inventor
  • Embree, Mallory
  • Gogul, Grant
  • Yang, Fan

Abstract

The disclosure relates to isolated microorganismsincluding novel strains of the microorganismsmicrobial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial compositions, and compositions comprising the same, in methods for treating or preventing gastrointestinal enteropathy or dysbiosis in canines. In particular aspects, the disclosure provides methods of treating or preventing morbidity and mortality caused by GI pathogenesis or autoimmunity.

IPC Classes  ?

  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A23K 50/40 - Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
  • A61K 35/74 - Bacteria
  • A61P 1/00 - Drugs for disorders of the alimentary tract or the digestive system
  • C12N 1/00 - Microorganisms, e.g. protozoaCompositions thereofProcesses of propagating, maintaining or preserving microorganisms or compositions thereofProcesses of preparing or isolating a composition containing a microorganismCulture media therefor
  • C12N 1/04 - Preserving or maintaining viable microorganisms
  • C12N 1/20 - BacteriaCulture media therefor
  • C12N 15/11 - DNA or RNA fragmentsModified forms thereof
  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria

28.

MICROBIAL COMPOSITIONS AND METHODS OF USE FOR CANINE ENTEROPATHY AND DYSBIOSIS

      
Application Number US2021017487
Publication Number 2021/163212
Status In Force
Filing Date 2021-02-10
Publication Date 2021-08-19
Owner NATIVE MICROBIALS, INC. (USA)
Inventor
  • Embree, Mallory
  • Gogul, Grant
  • Yang, Fan

Abstract

The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial compositions, and compositions comprising the same, in methods for treating or preventing gastrointestinal enteropathy or dysbiosis in canines. In particular aspects, the disclosure provides methods of treating or preventing morbidity and mortality caused by GI pathogenesis or autoimmunity.

IPC Classes  ?

  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A23K 50/42 - Dry feed
  • A23K 50/48 - Moist feed

29.

METHODS, APPARATUSES AND SYSTEMS FOR ANALYZING MICROORGANISM STRAINS FROM COMPLEX HETEROGENEOUS COMMUNITIES, PREDICTING AND IDENTIFYING FUNCTION RELATIONSHIPS AND INTERACTIONS THEREOF, AND SELECTING AND SYNTHESIZING MICROBIAL ENSEMBLES BASED THEREON

      
Application Number 16950641
Status Pending
Filing Date 2020-11-17
First Publication Date 2021-08-12
Owner Native Microbials, Inc. (USA)
Inventor Embree, Mallory

Abstract

Methods, apparatuses, and systems the screening, analyzing and selecting microorganisms from complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, synthesizing microbial ensembles based thereon, and forming and administering endomicrobial feed supplements are disclosed. Methods for identifying and determining the absolute cell count of microorganism types and strains, along identifying the network relationships between active microorganisms and environmental parameters, are also disclosed.

IPC Classes  ?

  • C12Q 1/06 - Quantitative determination
  • A23K 50/30 - Feeding-stuffs specially adapted for particular animals for swine
  • A23K 50/75 - Feeding-stuffs specially adapted for particular animals for birds for poultry
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A23K 10/16 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
  • A61K 35/74 - Bacteria
  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
  • G16B 40/00 - ICT specially adapted for biostatisticsICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
  • G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses
  • A23K 20/10 - Organic substances
  • A23K 50/70 - Feeding-stuffs specially adapted for particular animals for birds
  • G16B 20/00 - ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations

30.

Microbial compositions and methods of use for improving milk production

      
Application Number 17178552
Grant Number 11291219
Status In Force
Filing Date 2021-02-18
First Publication Date 2021-06-17
Grant Date 2022-04-05
Owner Native Microbials, Inc. (USA)
Inventor
  • Embree, Mallory
  • Picking, Luke
  • Gogul, Grant
  • Tarasova, Janna

Abstract

The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial consortia, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial consortia, and compositions comprising the same, in methods for modulating the production and yield of milk and milk components in ruminants. In particular aspects, the disclosure provides methods of increasing desirable components of milk in ruminants. Furthermore, the disclosure provides for methods of modulating the rumen microbiome.

IPC Classes  ?

  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A61K 36/062 - Ascomycota
  • A61P 15/04 - Drugs for genital or sexual disordersContraceptives for inducing labour or abortionUterotonics
  • A61K 35/74 - Bacteria
  • A61K 36/06 - Fungi, e.g. yeasts
  • A61K 36/064 - Saccharomycetales, e.g. baker's yeast
  • A23K 40/35 - Making capsules specially adapted for ruminants
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
  • A23L 31/10 - Yeasts or derivatives thereof
  • A23L 33/135 - Bacteria or derivatives thereof, e.g. probiotics
  • A61P 31/04 - Antibacterial agents
  • A61K 35/741 - Probiotics
  • A61K 39/02 - Bacterial antigens
  • C12N 1/14 - Fungi Culture media therefor
  • C12N 1/20 - BacteriaCulture media therefor
  • A23K 20/158 - Fatty acidsFatsProducts containing oils or fats
  • A23K 20/163 - SugarsPolysaccharides
  • A23K 20/28 - Silicates, e.g. perlites, zeolites or bentonites
  • A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
  • A23K 10/37 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms from waste material
  • A61K 35/748 - Cyanobacteria, i.e. blue-green bacteria or blue-green algae, e.g. spirulina

31.

Methods, apparatuses, and systems for analyzing complete microorganism strains in complex heterogeneous communities, determining functional relationships and interactions thereof, and identifying and synthesizing bioreactive modificators based thereon

      
Application Number 16475029
Grant Number 11891647
Status In Force
Filing Date 2017-12-28
First Publication Date 2021-04-22
Grant Date 2024-02-06
Owner Native Microbials, Inc. (USA)
Inventor
  • Embree, Mallory
  • Gaffney, James Russell
  • Martino, Cameron Joseph

Abstract

Methods, apparatuses, and systems for analyzing complete microorganism strains in complex heterogeneous communities, determining functional relationships and interactions thereof, and synthesizing bioreactive modificators based thereon are disclosed. Methods for identifying and utilizing pathways and functionalities of interest based thereon are also disclosed.

IPC Classes  ?

  • G01N 33/48 - Biological material, e.g. blood, urineHaemocytometers
  • C12Q 1/06 - Quantitative determination
  • G16B 20/00 - ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
  • C12Q 1/6869 - Methods for sequencing
  • G16B 5/20 - Probabilistic models
  • G16B 30/10 - Sequence alignmentHomology search
  • G16B 30/20 - Sequence assembly

32.

Ruminant compositions

      
Application Number 16920997
Grant Number 11910808
Status In Force
Filing Date 2020-07-06
First Publication Date 2021-02-11
Grant Date 2024-02-27
Owner Native Microbials, Inc. (USA)
Inventor
  • Embree, Mallory
  • Picking, Luke
  • Gogul, Grant
  • Tarasova, Janna

Abstract

The present disclosure provides compositions formulated for ruminants that comprise beneficial microbes. Particularly, the disclosure provides a composition comprising microorganisms with at least 97% sequence identity to any one of SEQ ID NOs: 1-60 and 2045-2107. Such compositions can be used for increasing milk production or improving milk compositional characteristics in ruminants.

IPC Classes  ?

  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A23L 33/135 - Bacteria or derivatives thereof, e.g. probiotics
  • A61K 35/74 - Bacteria
  • A61K 35/741 - Probiotics
  • A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
  • A61K 36/06 - Fungi, e.g. yeasts
  • A61K 36/062 - Ascomycota
  • A61P 15/04 - Drugs for genital or sexual disordersContraceptives for inducing labour or abortionUterotonics
  • A61K 36/064 - Saccharomycetales, e.g. baker's yeast
  • A23K 40/35 - Making capsules specially adapted for ruminants
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A23L 31/10 - Yeasts or derivatives thereof
  • A61P 31/04 - Antibacterial agents
  • A61K 39/02 - Bacterial antigens
  • C12N 1/14 - Fungi Culture media therefor
  • C12N 1/20 - BacteriaCulture media therefor
  • A23K 20/158 - Fatty acidsFatsProducts containing oils or fats
  • A23K 20/163 - SugarsPolysaccharides
  • A23K 20/28 - Silicates, e.g. perlites, zeolites or bentonites
  • A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
  • A23K 10/37 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms from waste material
  • A61K 35/748 - Cyanobacteria, i.e. blue-green bacteria or blue-green algae, e.g. spirulina

33.

METHODS AND SYSTEMS FOR STABILIZATION AND PRESERVATION OF MICROBES

      
Document Number 03136385
Status Pending
Filing Date 2020-04-09
Open to Public Date 2020-10-15
Owner NATIVE MICROBIALS, INC. (USA)
Inventor
  • Dodge, Corey
  • La, Rich
  • Taylor, Adam
  • Green, Howard
  • Radakovich, Gina
  • Gilmore, Sean

Abstract

The present disclosure relates to methods of stabilization of microbial compositions comprising combining a population of preserved microbial cells with at least one water activity scavenger (WAS) to a desired homogeneity level; and packaging and sealing the mixture of preserved microbial cells and the WAS. The present disclosure further relates to the stabilized microbial compositions and uses thereof.

IPC Classes  ?

  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A23L 33/135 - Bacteria or derivatives thereof, e.g. probiotics
  • A61K 35/74 - Bacteria
  • C12N 1/04 - Preserving or maintaining viable microorganisms
  • C12N 1/14 - Fungi Culture media therefor
  • C12N 1/20 - BacteriaCulture media therefor

34.

Microbial compositions and methods of use for improving milk production

      
Application Number 16871290
Grant Number 10966437
Status In Force
Filing Date 2020-05-11
First Publication Date 2020-10-01
Grant Date 2021-04-06
Owner Native Microbials, Inc. (USA)
Inventor
  • Embree, Mallory
  • Picking, Luke
  • Gogul, Grant
  • Tarasova, Janna

Abstract

The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial consortia, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial consortia, and compositions comprising the same, in methods for modulating the production and yield of milk and milk components in ruminants. In particular aspects, the disclosure provides methods of increasing desirable components of milk in ruminants. Furthermore, the disclosure provides for methods of modulating the rumen microbiome.

IPC Classes  ?

  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A61K 36/062 - Ascomycota
  • A61P 15/04 - Drugs for genital or sexual disordersContraceptives for inducing labour or abortionUterotonics
  • A61K 35/74 - Bacteria
  • A61K 36/06 - Fungi, e.g. yeasts
  • A61K 36/064 - Saccharomycetales, e.g. baker's yeast
  • A23K 40/35 - Making capsules specially adapted for ruminants
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
  • A23L 31/10 - Yeasts or derivatives thereof
  • A23L 33/135 - Bacteria or derivatives thereof, e.g. probiotics
  • A61P 31/04 - Antibacterial agents
  • A61K 35/741 - Probiotics
  • A61K 39/02 - Bacterial antigens
  • C12N 1/14 - Fungi Culture media therefor
  • C12N 1/20 - BacteriaCulture media therefor
  • A23K 20/158 - Fatty acidsFatsProducts containing oils or fats
  • A23K 20/163 - SugarsPolysaccharides
  • A23K 20/28 - Silicates, e.g. perlites, zeolites or bentonites
  • A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
  • A23K 10/37 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms from waste material
  • A61K 35/748 - Cyanobacteria, i.e. blue-green bacteria or blue-green algae, e.g. spirulina

35.

METHODS, APPARATUSES, AND SYSTEMS FOR IMPROVING MICROBIAL PRESERVATION YIELD THROUGH RESCUE AND SERIAL PASSAGE OF PRESERVED CELLS

      
Document Number 03130278
Status Pending
Filing Date 2020-02-28
Open to Public Date 2020-09-03
Owner NATIVE MICROBIALS, INC. (USA)
Inventor
  • Gilmore, Sean
  • Dodge, Corey

Abstract

The present disclosure provides methods of improving microbe viability after preservation comprising subjecting a population of target microbial cells to one or more preservation challenges and preparing a product using the population of preserved viability-enhanced microbial cells produced from said methods. The present disclosure further provides products comprising preserved viability-enhanced microbial cells produced by the methods described herein.

IPC Classes  ?

  • C12N 1/00 - Microorganisms, e.g. protozoaCompositions thereofProcesses of propagating, maintaining or preserving microorganisms or compositions thereofProcesses of preparing or isolating a composition containing a microorganismCulture media therefor
  • C12N 1/04 - Preserving or maintaining viable microorganisms
  • C12N 1/14 - Fungi Culture media therefor
  • C12N 1/20 - BacteriaCulture media therefor

36.

Compositions and methods of decreasing feed conversion ratios in fowl

      
Application Number 16853351
Grant Number 11000049
Status In Force
Filing Date 2020-04-20
First Publication Date 2020-08-06
Grant Date 2021-05-11
Owner Native Microbials, Inc. (USA)
Inventor
  • Embree, Mallory
  • Gogul, Grant
  • Martino, Cameron
  • Pitt, Norm

Abstract

Bacillus sp. to the fowl. The disclosure further relates to isolated microorganisms and compositions comprising the same.

IPC Classes  ?

  • A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
  • A61K 35/747 - Lactobacilli, e.g. L. acidophilus or L. brevis
  • C12N 1/20 - BacteriaCulture media therefor
  • A61K 35/00 - Medicinal preparations containing materials or reaction products thereof with undetermined constitution
  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A23K 40/30 - Shaping or working-up of animal feeding-stuffs by encapsulatingShaping or working-up of animal feeding-stuffs by coating
  • A23K 50/75 - Feeding-stuffs specially adapted for particular animals for birds for poultry
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • C12R 1/01 - Bacteria or actinomycetales
  • A01K 45/00 - Other aviculture appliances, e.g. devices for determining whether a bird is about to lay
  • C12R 1/225 - Lactobacillus

37.

N

      
Serial Number 90003940
Status Registered
Filing Date 2020-06-16
Registration Date 2021-08-17
Owner Native Microbials, Inc ()
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Nutritional supplements for animals; nutritional supplements, namely, endomicrobial feed supplements for animals containing native microorganisms; animal feed additives for use as a nutritional supplement; nutritional additives for feed or water for animals for use as a nutritional supplement; microbial products for animals, namely, cultures of micro-organisms to aid digestion, for use as a nutritional supplement

38.

NATIVE MICROBIALS

      
Serial Number 88958345
Status Registered
Filing Date 2020-06-10
Registration Date 2021-09-07
Owner NATIVE MICROBIALS, INC. ()
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Nutritional supplements for animals; nutritional supplements, namely, endomicrobial feed supplements for animals containing native microorganisms; animal feed additives for use as a nutritional supplement; nutritional additives for feed or water for animals for use as a nutritional supplement; microbial products for animals, namely, cultures of micro-organisms to aid digestion, for use as a nutritional supplement

39.

A

      
Serial Number 88918397
Status Registered
Filing Date 2020-05-15
Registration Date 2021-02-16
Owner NATIVE MICROBIALS, INC. ()
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Nutritional supplements for animals; nutritional supplements, namely, endomicrobial feed supplements for animals containing native microorganisms; animal feed additives for use as a nutritional supplement; nutritional additives for feed or water for animals for use as a nutritional supplement; microbial products for animals, namely, cultures of micro-organisms to aid digestion, for use as a nutritional supplement

40.

ASCUS

      
Serial Number 88918394
Status Registered
Filing Date 2020-05-15
Registration Date 2021-02-16
Owner NATIVE MICROBIALS, INC. ()
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Nutritional supplements for animals; nutritional supplements, namely, endomicrobial feed supplements for animals containing native microorganisms; animal feed additives for use as a nutritional supplement; nutritional additives for feed or water for animals for use as a nutritional supplement; microbial products for animals, namely, cultures of micro-organisms to aid digestion, for use as a nutritional supplement

41.

ASCUS BIOSCIENCES

      
Serial Number 88918396
Status Registered
Filing Date 2020-05-15
Registration Date 2021-02-16
Owner NATIVE MICROBIALS, INC. ()
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Nutritional supplements for animals; nutritional supplements, namely, endomicrobial feed supplements for animals containing native microorganisms; animal feed additives for use as a nutritional supplement; nutritional additives for feed or water for animals for use as a nutritional supplement; microbial products for animals, namely, cultures of micro-organisms to aid digestion, for use as a nutritional supplement

42.

Ruminant compositions

      
Application Number 16655776
Grant Number 10701955
Status In Force
Filing Date 2019-10-17
First Publication Date 2020-02-06
Grant Date 2020-07-07
Owner NATIVE MICROBIALS, INC. (USA)
Inventor
  • Embree, Mallory
  • Picking, Luke
  • Gogul, Grant
  • Tarasova, Janna

Abstract

The disclosure relates to compositions beneficial for ruminant administration. Particularly, the disclosure provides compositions formulated for ruminants that comprise beneficial microbes.

IPC Classes  ?

  • A23K 10/16 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
  • A61K 35/74 - Bacteria
  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A61K 36/062 - Ascomycota
  • A61P 15/04 - Drugs for genital or sexual disordersContraceptives for inducing labour or abortionUterotonics
  • A61K 36/06 - Fungi, e.g. yeasts
  • A61K 36/064 - Saccharomycetales, e.g. baker's yeast
  • A23K 40/35 - Making capsules specially adapted for ruminants
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
  • A23L 31/10 - Yeasts or derivatives thereof
  • A23L 33/135 - Bacteria or derivatives thereof, e.g. probiotics
  • A61P 31/04 - Antibacterial agents
  • A61K 35/741 - Probiotics
  • A61K 39/02 - Bacterial antigens
  • C12N 1/14 - Fungi Culture media therefor
  • C12N 1/20 - BacteriaCulture media therefor
  • A23K 20/158 - Fatty acidsFatsProducts containing oils or fats
  • A23K 20/163 - SugarsPolysaccharides
  • A23K 20/28 - Silicates, e.g. perlites, zeolites or bentonites
  • A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
  • A23K 10/37 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms from waste material
  • A61K 35/748 - Cyanobacteria, i.e. blue-green bacteria or blue-green algae, e.g. spirulina

43.

METHODS, APPARATUSES, AND SYSTEMS FOR ANALYZING MICROORGANISM STRAINS IN COMPLEX HETEROGENEOUS COMMUNITIES, DETERMINING FUNCTIONAL RELATIONSHIPS AND INTERACTIONS THEREOF, AND DIAGNOSTICS AND BIOSTATE MANAGEMENT AND BIOSTATE TEMPORAL FORECASTING BASED THEREON

      
Application Number 16446143
Status Pending
Filing Date 2019-06-19
First Publication Date 2019-12-05
Owner NATIVE MICROBIALS, INC. (USA)
Inventor
  • Embree, Mallory
  • Martino, Cameron Joseph

Abstract

Methods, apparatuses, and systems for analyzing microorganism strains in complex heterogeneous communities, determining functional relationships and interactions thereof, and diagnostics and biostate management and biostate temporal forecasting based thereon are disclosed. Methods for diagnostics, analytics, and treatments of states and state aberrations/deviations, including treatments, such as bioreactive modificators, such as bioreactive modificators comprising synthetic microbial ensembles, are also disclosed.

IPC Classes  ?

  • G16B 5/00 - ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
  • C12Q 1/04 - Determining presence or kind of microorganismUse of selective media for testing antibiotics or bacteriocidesCompositions containing a chemical indicator therefor
  • C12Q 1/08 - Quantitative determination using multifield media
  • C12Q 1/6874 - Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation [SBH]
  • G16B 40/30 - Unsupervised data analysis
  • G16B 40/20 - Supervised data analysis
  • A61K 35/741 - Probiotics
  • A23K 10/10 - Animal feeding-stuffs obtained by microbiological or biochemical processes
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants

44.

Microbial compositions and methods of use for improving milk production

      
Application Number 16534481
Grant Number 10645952
Status In Force
Filing Date 2019-08-07
First Publication Date 2019-11-28
Grant Date 2020-05-12
Owner NATIVE MICROBIALS, INC. (USA)
Inventor
  • Embree, Mallory
  • Picking, Luke
  • Gogul, Grant
  • Tarasova, Janna

Abstract

The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial consortia, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial consortia, and compositions comprising the same, in methods for modulating the production and yield of milk and milk components in ruminants. In particular aspects, the disclosure provides methods of increasing desirable components of milk in ruminants. Furthermore, the disclosure provides for methods of modulating the rumen microbiome.

IPC Classes  ?

  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A61P 15/04 - Drugs for genital or sexual disordersContraceptives for inducing labour or abortionUterotonics
  • A61K 35/74 - Bacteria
  • A61K 36/062 - Ascomycota
  • C12N 1/20 - BacteriaCulture media therefor
  • C12N 1/14 - Fungi Culture media therefor
  • A23L 31/10 - Yeasts or derivatives thereof
  • A23L 33/135 - Bacteria or derivatives thereof, e.g. probiotics
  • A61P 31/04 - Antibacterial agents
  • A61K 35/741 - Probiotics
  • A61K 39/02 - Bacterial antigens
  • A23K 10/37 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms from waste material
  • A23K 20/28 - Silicates, e.g. perlites, zeolites or bentonites
  • A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
  • A23K 20/163 - SugarsPolysaccharides
  • A23K 20/158 - Fatty acidsFatsProducts containing oils or fats
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A23K 40/35 - Making capsules specially adapted for ruminants
  • A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 36/064 - Saccharomycetales, e.g. baker's yeast
  • A61K 36/06 - Fungi, e.g. yeasts
  • A61K 35/748 - Cyanobacteria, i.e. blue-green bacteria or blue-green algae, e.g. spirulina

45.

Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities with tracer analytics, determination of functional relationships and interactions thereof, and synthesis of microbial ensembles

      
Application Number 16475033
Grant Number 12018313
Status In Force
Filing Date 2017-12-28
First Publication Date 2019-10-24
Grant Date 2024-06-25
Owner Native Microbials, Inc. (USA)
Inventor Embree, Mallory

Abstract

Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities with tracer analytics, determination of functional relationships and interactions thereof, and synthesis of microbial ensembles, including dosed microbial ensembles and inoculative microbial ensembles, are disclosed.

IPC Classes  ?

  • C12Q 1/06 - Quantitative determination
  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
  • G16B 5/00 - ICT specially adapted for modelling or simulations in systems biology, e.g. gene-regulatory networks, protein interaction networks or metabolic networks
  • G16B 5/20 - Probabilistic models
  • G16B 40/10 - Signal processing, e.g. from mass spectrometry [MS] or from PCR

46.

Cow food and methods of husbandry for increased milk production

      
Application Number 16206098
Grant Number 10448657
Status In Force
Filing Date 2018-11-30
First Publication Date 2019-09-19
Grant Date 2019-10-22
Owner NATIVE MICROBIALS, INC. (USA)
Inventor
  • Embree, Mallory
  • Picking, Luke
  • Gogul, Grant
  • Tarasova, Janna

Abstract

Clostridium sp.

IPC Classes  ?

  • C12N 1/14 - Fungi Culture media therefor
  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A61K 36/064 - Saccharomycetales, e.g. baker's yeast
  • A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
  • A23K 40/35 - Making capsules specially adapted for ruminants

47.

Methods for improving agricultural production of fowl by administration of microbial compositions or purified strains thereof

      
Application Number 16093923
Grant Number 10617134
Status In Force
Filing Date 2017-04-17
First Publication Date 2019-09-05
Grant Date 2020-04-14
Owner NATIVE MICROBIALS, INC. (USA)
Inventor
  • Embree, Mallory
  • Gogul, Grant
  • Martino, Cameron
  • Pitt, Norm

Abstract

The disclosure relates to isolated microorganisms-including novel strains of the microorganisms-microbial consortia, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial consortia, and compositions comprising the same, in methods for modulating the production of poultry, disease resistance, and egg yield. In particular aspects, the disclosure provides methods of increasing feed efficiency, and methods of preventing colonization of pathogenic microbes.

IPC Classes  ?

  • A61K 35/00 - Medicinal preparations containing materials or reaction products thereof with undetermined constitution
  • A61K 35/747 - Lactobacilli, e.g. L. acidophilus or L. brevis
  • A61K 35/741 - Probiotics
  • A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A23K 50/75 - Feeding-stuffs specially adapted for particular animals for birds for poultry
  • A23K 40/30 - Shaping or working-up of animal feeding-stuffs by encapsulatingShaping or working-up of animal feeding-stuffs by coating
  • C12N 1/20 - BacteriaCulture media therefor
  • C12R 1/01 - Bacteria or actinomycetales

48.

Methods of decreasing feed conversion ratios in fowl

      
Application Number 16218074
Grant Number 10624366
Status In Force
Filing Date 2018-12-12
First Publication Date 2019-08-22
Grant Date 2020-04-21
Owner NATIVE MICROBIALS, INC. (USA)
Inventor
  • Embree, Mallory
  • Gogul, Grant
  • Martino, Cameron
  • Pitt, Norm

Abstract

Bacillus sp. to the fowl. The disclosure further relates to isolated microorganisms and compositions comprising the same.

IPC Classes  ?

  • A61K 35/00 - Medicinal preparations containing materials or reaction products thereof with undetermined constitution
  • A61K 35/747 - Lactobacilli, e.g. L. acidophilus or L. brevis
  • A61K 35/741 - Probiotics
  • A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A23K 50/75 - Feeding-stuffs specially adapted for particular animals for birds for poultry
  • A23K 40/30 - Shaping or working-up of animal feeding-stuffs by encapsulatingShaping or working-up of animal feeding-stuffs by coating
  • A01K 45/00 - Other aviculture appliances, e.g. devices for determining whether a bird is about to lay
  • C12N 1/20 - BacteriaCulture media therefor
  • C12R 1/225 - Lactobacillus
  • C12R 1/01 - Bacteria or actinomycetales

49.

Cow food and methods of husbandry for increased milk production

      
Application Number 16207811
Grant Number 10448658
Status In Force
Filing Date 2018-12-03
First Publication Date 2019-07-04
Grant Date 2019-10-22
Owner NATIVE MICROBIALS, INC. (USA)
Inventor
  • Embree, Mallory
  • Picking, Luke
  • Gogul, Grant
  • Tarasova, Janna

Abstract

Clostridium sp.

IPC Classes  ?

  • C12N 1/14 - Fungi Culture media therefor
  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A61K 35/74 - Bacteria
  • A61K 36/06 - Fungi, e.g. yeasts
  • A61K 36/064 - Saccharomycetales, e.g. baker's yeast
  • A23K 40/35 - Making capsules specially adapted for ruminants
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
  • A23L 31/10 - Yeasts or derivatives thereof
  • A23L 33/135 - Bacteria or derivatives thereof, e.g. probiotics
  • A61P 31/04 - Antibacterial agents
  • A61K 35/741 - Probiotics
  • A61K 39/02 - Bacterial antigens
  • C12N 1/20 - BacteriaCulture media therefor
  • A23K 20/158 - Fatty acidsFatsProducts containing oils or fats
  • A23K 20/163 - SugarsPolysaccharides
  • A23K 20/28 - Silicates, e.g. perlites, zeolites or bentonites
  • A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
  • A23K 10/37 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms from waste material

50.

Microbial compositions and methods of use for improving fowl production

      
Application Number 16042369
Grant Number 10632157
Status In Force
Filing Date 2018-07-23
First Publication Date 2018-11-22
Grant Date 2020-04-28
Owner NATIVE MICROBIALS, INC. (USA)
Inventor
  • Embree, Mallory
  • Gogul, Grant
  • Martino, Cameron
  • Pitt, Norm

Abstract

The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial ensembles, and compositions comprising the same, in methods for modulating the production of poultry, disease resistance, and egg yield. In particular aspects, the disclosure provides methods of increasing feed efficiency, and methods of preventing colonization of pathogenic microbes.

IPC Classes  ?

  • A61K 35/00 - Medicinal preparations containing materials or reaction products thereof with undetermined constitution
  • A61K 35/747 - Lactobacilli, e.g. L. acidophilus or L. brevis
  • A61K 35/741 - Probiotics
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A23K 50/75 - Feeding-stuffs specially adapted for particular animals for birds for poultry

51.

Microbial compositions and methods of use for improving milk production

      
Application Number 16029398
Grant Number 10398154
Status In Force
Filing Date 2018-07-06
First Publication Date 2018-11-15
Grant Date 2019-09-03
Owner NATIVE MICROBIALS, INC. (USA)
Inventor
  • Embree, Mallory
  • Picking, Luke
  • Gogul, Grant
  • Tarasova, Janna

Abstract

The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial consortia, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial consortia, and compositions comprising the same, in methods for modulating the production and yield of milk and milk components in ruminants. In particular aspects, the disclosure provides methods of increasing desirable components of milk in ruminants. Furthermore, the disclosure provides for methods of modulating the rumen microbiome.

IPC Classes  ?

  • A61K 36/064 - Saccharomycetales, e.g. baker's yeast
  • A61K 36/04 - Rhodophycota or rhodophyta (red algae), e.g. Porphyra
  • A61K 35/74 - Bacteria
  • A61K 35/741 - Probiotics
  • A61K 36/06 - Fungi, e.g. yeasts
  • A23K 40/35 - Making capsules specially adapted for ruminants
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A23L 31/10 - Yeasts or derivatives thereof
  • A23L 33/135 - Bacteria or derivatives thereof, e.g. probiotics
  • A61P 31/04 - Antibacterial agents
  • A61K 39/02 - Bacterial antigens
  • C12N 1/14 - Fungi Culture media therefor
  • C12N 1/20 - BacteriaCulture media therefor
  • A23K 20/158 - Fatty acidsFatsProducts containing oils or fats
  • A23K 20/163 - SugarsPolysaccharides
  • A23K 20/28 - Silicates, e.g. perlites, zeolites or bentonites
  • A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
  • A23K 10/37 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms from waste material

52.

Methods for supporting grain intensive and or energy intensive diets in ruminants by administration of a synthetic bioensemble of microbes or purified strains therefor

      
Application Number 15965661
Grant Number 11044924
Status In Force
Filing Date 2018-04-27
First Publication Date 2018-11-01
Grant Date 2021-06-29
Owner Native Microbials, Inc. (USA)
Inventor
  • Embree, Mallory
  • Martino, Cameron
  • Pitt, Norman
  • Embree, Jordan
  • Dodge, Corey

Abstract

The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial compositions, and compositions comprising the same, in methods for modulating the agricultural production of ruminants. In particular aspects, the disclosure provides methods of increasing feed efficiency, and methods of decreasing acidosis.

IPC Classes  ?

  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A61K 35/74 - Bacteria
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A61P 1/04 - Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

53.

METHODS FOR SUPPORTING GRAIN INTENSIVE AND/OR ENERGY INTENSIVE DIETS IN RUMINANTS BY ADMINISTRATION OF A SYNTHETIC BIOENSEMBLE OF MICROBES OR PURIFIED STRAINS THEREOF

      
Document Number 03057692
Status Pending
Filing Date 2018-04-27
Open to Public Date 2018-11-01
Owner NATIVE MICROBIALS, INC. (USA)
Inventor
  • Embree, Mallory
  • Martino, Cameron
  • Pitt, Norman
  • Embree, Jordan
  • Dodge, Corey

Abstract

The disclosure relates to isolated microorganisms-including novel strains of the microorganisms-microbial ensembles, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial compositions, and compositions comprising the same, in methods for modulating the agricultural production of ruminants. In particular aspects, the disclosure provides methods of increasing feed efficiency, and methods of decreasing acidosis.

IPC Classes  ?

  • A23K 10/16 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A61K 9/48 - Preparations in capsules, e.g. of gelatin, of chocolate
  • A61K 35/74 - Bacteria
  • A61P 1/14 - Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
  • C12N 1/20 - BacteriaCulture media therefor

54.

Methods, apparatuses and systems for analyzing microorganism strains from complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon

      
Application Number 15948965
Grant Number 10870877
Status In Force
Filing Date 2018-04-09
First Publication Date 2018-08-09
Grant Date 2020-12-22
Owner Native Microbials, Inc. (USA)
Inventor Embree, Mallory

Abstract

Methods, apparatuses, and systems for screening, analyzing and selecting microorganisms from complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, synthesizing microbial ensembles based thereon, and forming and administering endomicrobial feed supplements are disclosed. Methods for identifying and determining the absolute cell count of microorganism types and strains, along with identifying the network relationships between active microorganisms and environmental parameters, are also disclosed.

IPC Classes  ?

  • C12Q 1/06 - Quantitative determination
  • A23K 50/30 - Feeding-stuffs specially adapted for particular animals for swine
  • A23K 50/75 - Feeding-stuffs specially adapted for particular animals for birds for poultry
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A23K 10/16 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
  • A61K 35/74 - Bacteria
  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
  • G16B 40/00 - ICT specially adapted for biostatisticsICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
  • G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses
  • A23K 20/10 - Organic substances
  • A23K 50/70 - Feeding-stuffs specially adapted for particular animals for birds
  • G16B 20/00 - ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
  • C12Q 1/6874 - Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation [SBH]

55.

Methods, apparatuses, and systems for analyzing microorganism strains from complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon

      
Application Number 15791391
Grant Number 09938558
Status In Force
Filing Date 2017-10-23
First Publication Date 2018-02-15
Grant Date 2018-04-10
Owner NATIVE MICROBIALS, INC. (USA)
Inventor Embree, Mallory

Abstract

Methods, apparatuses, and systems for screening, analyzing and selecting microorganisms from complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and synthesizing microbial ensembles based thereon are disclosed. Methods for identifying and determining the absolute cell count of microorganism types and strains, along with identifying the network relationships between active microorganisms and environmental parameters, are also disclosed.

IPC Classes  ?

  • A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
  • C12Q 1/06 - Quantitative determination
  • A23K 50/30 - Feeding-stuffs specially adapted for particular animals for swine
  • A23K 50/75 - Feeding-stuffs specially adapted for particular animals for birds for poultry
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A23K 10/16 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
  • A61K 35/74 - Bacteria
  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids

56.

GALAXIS

      
Serial Number 87716218
Status Registered
Filing Date 2017-12-11
Registration Date 2021-03-16
Owner NATIVE MICROBIALS, INC. ()
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Nutritional supplements for animals; animal feed additives for use as a nutritional supplement; nutritional additives for feed or water for animals for use as a nutritional supplement; microbial products for animals, namely, cultures of micro-organisms to aid digestion, for use as a nutritional supplement; Microbial feed supplements for administration to animals; Probiotics supplements for animals; Protein supplements for animals; Dietary supplements for animals; Animal feed supplements; Non-medicated additives for animal feed for use as nutritional supplements

57.

Methods, apparatuses, and systems for analyzing microorganism strains from complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon

      
Application Number 15349829
Grant Number 10844419
Status In Force
Filing Date 2016-11-11
First Publication Date 2017-11-30
Grant Date 2020-11-24
Owner Native Microbials, Inc. (USA)
Inventor Embree, Mallory

Abstract

Methods, apparatuses, and systems for screening, analyzing and selecting microorganisms from complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and synthesizing microbial ensembles based thereon are disclosed. Methods for identifying and determining the absolute cell count of microorganism types and strains, along with identifying the network relationships between active microorganisms and environmental parameters, are also disclosed.

IPC Classes  ?

  • A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
  • C12Q 1/06 - Quantitative determination
  • A61K 35/74 - Bacteria
  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A23K 10/16 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A23K 50/75 - Feeding-stuffs specially adapted for particular animals for birds for poultry
  • A23K 50/30 - Feeding-stuffs specially adapted for particular animals for swine
  • C12Q 1/6874 - Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation [SBH]

58.

METHODS FOR IMPROVING AGRICULTURAL PRODUCTION OF FOWL BY ADMINISTRATION OF MICROBIAL CONSORTIA OR PURIFIED STRAINS THEREOF

      
Document Number 03020833
Status Pending
Filing Date 2017-04-17
Open to Public Date 2017-10-19
Owner NATIVE MICROBIALS, INC. (USA)
Inventor
  • Embree, Mallory
  • Tarasova, Janna
  • Picking, Luke
  • Gogul, Grant
  • Vanderlinden, Kayla

Abstract

The disclosure relates to isolated microorganisms-including novel strains of the microorganisms-microbial consortia, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial consortia, and compositions comprising the same, in methods for modulating the production of poultry, disease resistance, and egg yield. In particular aspects, the disclosure provides methods of increasing feed efficiency, and methods of preventing colonization of pathogenic microbes.

IPC Classes  ?

  • A23K 10/16 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
  • A23K 50/70 - Feeding-stuffs specially adapted for particular animals for birds
  • A23K 50/75 - Feeding-stuffs specially adapted for particular animals for birds for poultry
  • A61K 35/74 - Bacteria
  • A61K 35/747 - Lactobacilli, e.g. L. acidophilus or L. brevis
  • C12N 1/14 - Fungi Culture media therefor
  • C12N 1/20 - BacteriaCulture media therefor

59.

Microbial compositions for improving milk production in ruminants

      
Application Number 15400436
Grant Number 10293006
Status In Force
Filing Date 2017-01-06
First Publication Date 2017-07-13
Grant Date 2019-05-21
Owner NATIVE MICROBIALS, INC. (USA)
Inventor
  • Embree, Mallory
  • Picking, Luke
  • Gogul, Grant
  • Tarasova, Janna

Abstract

The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial consortia, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial consortia, and compositions comprising the same, in methods for modulating the production and yield of milk and milk components in ruminants. In particular aspects, the disclosure provides methods of increasing desirable components of milk in ruminants. Furthermore, the disclosure provides for methods of modulating the rumen microbiome.

IPC Classes  ?

  • A61K 36/064 - Saccharomycetales, e.g. baker's yeast
  • A61K 36/04 - Rhodophycota or rhodophyta (red algae), e.g. Porphyra
  • A61K 35/74 - Bacteria
  • A61K 35/741 - Probiotics
  • A61K 36/06 - Fungi, e.g. yeasts
  • A23K 40/35 - Making capsules specially adapted for ruminants
  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
  • A23L 31/10 - Yeasts or derivatives thereof
  • A23L 33/135 - Bacteria or derivatives thereof, e.g. probiotics
  • A61P 31/04 - Antibacterial agents
  • A61K 39/02 - Bacterial antigens
  • C12N 1/14 - Fungi Culture media therefor
  • C12N 1/20 - BacteriaCulture media therefor

60.

Methods of improving milk production and compositional characteristics

      
Application Number 15400484
Grant Number 09993507
Status In Force
Filing Date 2017-01-06
First Publication Date 2017-07-13
Grant Date 2018-06-12
Owner NATIVE MICROBIALS, INC. (USA)
Inventor
  • Embree, Mallory
  • Picking, Luke
  • Gogul, Grant
  • Tarasova, Janna

Abstract

The disclosure relates to isolated microorganisms—including novel strains of the microorganisms—microbial consortia, and compositions comprising the same. Furthermore, the disclosure teaches methods of utilizing the described microorganisms, microbial consortia, and compositions comprising the same, in methods for modulating the production and yield of milk and milk components in ruminants. In particular aspects, the disclosure provides methods of increasing desirable components of milk in ruminants. Furthermore, the disclosure provides for methods of modulating the rumen microbiome.

IPC Classes  ?

  • A23K 50/10 - Feeding-stuffs specially adapted for particular animals for ruminants
  • A61K 36/064 - Saccharomycetales, e.g. baker's yeast
  • A61K 35/74 - Bacteria
  • A61K 36/06 - Fungi, e.g. yeasts
  • A23K 40/35 - Making capsules specially adapted for ruminants
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
  • A23K 10/18 - Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms

61.

Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon

      
Application Number 15392913
Grant Number 10851399
Status In Force
Filing Date 2016-12-28
First Publication Date 2017-04-20
Grant Date 2020-12-01
Owner Native Microbials, Inc. (USA)
Inventor Embree, Mallory

Abstract

Methods, apparatuses, and systems for microorganism strain analysis of complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon are disclosed. Methods for identifying and determining the absolute cell count of microorganism types and strains, along with identifying the network relationships between active microorganisms and metadata, are also disclosed.

IPC Classes  ?

  • A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
  • C12Q 1/06 - Quantitative determination
  • G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses
  • A23K 20/10 - Organic substances
  • A23K 50/70 - Feeding-stuffs specially adapted for particular animals for birds
  • G16B 40/00 - ICT specially adapted for biostatisticsICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria

62.

Methods, apparatuses, and systems for analyzing microorganism strains from complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and selecting and synthesizing microbial ensembles based thereon

      
Application Number 15217575
Grant Number 09540676
Status In Force
Filing Date 2016-07-22
First Publication Date 2016-12-29
Grant Date 2017-01-10
Owner NATIVE MICROBIALS, INC. (USA)
Inventor
  • Zengler, Karsten
  • Embree, Mallory

Abstract

Methods, apparatuses, and systems for screening, analyzing and selecting microorganisms from complex heterogeneous communities, predicting and identifying functional relationships and interactions thereof, and synthesizing microbial ensembles based thereon are disclosed. Methods for identifying and determining the absolute cell count of microorganism types and strains, along with identifying the network relationships between active microorganisms and environmental parameters, are also disclosed.

IPC Classes  ?

  • A01N 63/00 - Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
  • C12Q 1/06 - Quantitative determination
  • A61K 35/74 - Bacteria
  • C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids