Provided herein are devices and methods for improved oxygenation of biological cells transplanted into a biological subject. The devices and methods may be used to promote vascularization to a transplantation site of the biological subject, and/or may be used to improve survival and functionality of cells contained within an encapsulation device.
A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
Disclosed herein are devices for encapsulating biological cells and are suitable to be implanted into a subject. In different aspects of the disclosure, the devices may comprise a plurality of polymer layers. In one aspect, a device comprises a first polymer layer and a second polymer layer. In some cases, the first polymer layer may be a nanoporous polymer layer. In some cases, the second polymer layer may be a macroporous polymer layer. The first and second polymer layers may define a lumen for enclosing a population of cells. The devices may be used to transplant cells producing therapeutic agents into a subject (e.g., for the treatment of a disease).
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Pharmaceutical products for treatment of chronic diseases by means of gene and cell therapy, encapsulated cell therapy, and implantable cell therapy; living cells for implantable cell therapy; living cells for gene and cell therapy, encapsulated cell therapy, and implantable cell therapy; living cells for medical use, namely, encapsulated cells delivered by implantable cell therapy devices for secreting drugs and/or molecules; encapsulated pharmaceutical products for the treatment of chronic diseases; implantable pharmaceutical products for the treatment of chronic diseases; encapsulated pharmaceutical product for the treatment of chronic diseases delivered by implantable encapsulation devices with encapsulated cells for secreting drugs Cell encapsulation devices in the nature of implantable drug and/or molecule and cell therapy delivery ports; implantable cell encapsulation devices in the nature of implantable drug and/or molecule and cell therapy delivery ports; implantable cell therapy devices in the nature of implantable drug and/or molecule and cell therapy delivery ports; drug and prescription encapsulation devices in the nature of implantable drug and cell therapy delivery ports; implantable drug and prescription encapsulation devices in the nature of implantable drug and cell therapy delivery ports; implantable drug and prescription delivery devices in the nature of implantable drug and cell therapy delivery ports
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
(1) Pharmaceutical preparations for use in gene and cell therapy; pharmaceutical products in the nature of encapsulated living cells for gene and cell therapy; biological preparations made from living cells for use in cell therapy; biological preparations made from living cells for use in cell therapy in the nature of implantable living cells.
(2) Cell encapsulation medical devices in the nature of a nano-porous polymeric pouch designed to encapsulate therapeutic cells for delivery to human organs; implantable medical devices in the nature of nano-porous, polymeric pouches designed to encapsulate therapeutic cells and be implanted subcutaneously; nano-parous polymeric implants in the nature of pouches containing encapsulated therapeutic cells.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Pharmaceutical products for treatment of chronic diseases by means of gene and cell therapy, encapsulated cell therapy, and implantable cell therapy; living cells for implantable cell therapy; living cells for gene and cell therapy, encapsulated cell therapy, and implantable cell therapy; living cells for medical use, namely, implantable cell therapy preparations with encapsulated cells for secreting drugs and/or molecules Cell encapsulation devices in the nature of implantable cell therapy delivery ports; implantable cell encapsulation devices in the nature of implantable cell therapy delivery ports; implantable cell therapy devices in the nature of implantable cell therapy delivery ports
6.
CELL ENCAPSULATION DEVICES AND METHODS OF USING SAME
Disclosed herein are devices for encapsulating biological cells and are suitable to be implanted into a subject. In different aspects of the disclosure, the devices may comprise a plurality of polymer layers. In one aspect, a device comprises a first polymer layer and a second polymer layer. In some cases, the first polymer layer may be a nanoporous polymer layer. In some cases, the second polymer layer may be a macroporous polymer layer. The first and second polymer layers may define a lumen for enclosing a population of cells. In some cases, the device further comprises a third polymer layer. The devices may be used to transplant cells producing therapeutic agents into a subject (e.g., for the treatment of a disease).
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
Provided herein are devices and methods for improved oxygenation of biological cells transplanted into a biological subject. The devices and methods may be used to promote vascularization to a transplantation site of the biological subject, and/or may be used to improve survival and functionality of cells contained within an encapsulation device.
A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
A61L 27/18 - Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
The present disclosure provides a filtration media for filtering one or more airborne particles. The filtration media may comprise a membrane comprising one or more polymeric layers to filter the airborne particles. The filtration media may have high filtration efficiency and high breathability. Additionally, the present disclosure provides devices (e.g., face masks) comprising the filtration media which may be used to filter airborne particles (e.g., bacteria, viruses) and to protect the wearer (e.g., from infection).
B01D 69/02 - Semi-permeable membranes for separation processes or apparatus characterised by their form, structure or propertiesManufacturing processes specially adapted therefor characterised by their properties
9.
CELL ENCAPSULATION DEVICES AND METHODS OF USING SAME
Disclosed herein are devices for encapsulating biological cells and are suitable to be implanted into a subject. In different aspects of the disclosure, the devices may comprise a plurality of polymer layers. In one aspect, a device comprises a first polymer layer and a second polymer layer. In some cases, the first polymer layer may be a nanoporous polymer layer. In some cases, the second polymer layer may be a macroporous polymer layer. The first and second polymer layers may define a lumen for enclosing a population of cells. The devices may be used to transplant cells producing therapeutic agents into a subject (e.g., for the treatment of a disease).
Disclosed herein are devices for encapsulating biological cells and are suitable to be implanted into a subject. In different aspects of the disclosure, the devices may comprise a plurality of polymer layers. In one aspect, a device comprises a first polymer layer and a second polymer layer. In some cases, the first polymer layer may be a nanoporous polymer layer. In some cases, the second polymer layer may be a macroporous polymer layer. The first and second polymer layers may define a lumen for enclosing a population of cells. In some cases, the device further comprises a third polymer layer. The devices may be used to transplant cells producing therapeutic agents into a subject (e.g., for the treatment of a disease).
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61L 27/36 - Materials for prostheses or for coating prostheses containing ingredients of undetermined constitution or reaction products thereof
Disclosed herein are devices for encapsulating biological cells and are suitable to be implanted into a subject. In different aspects of the disclosure, the devices may comprise a plurality of polymer layers. In one aspect, a device comprises a first polymer layer and a second polymer layer. In some cases, the first polymer layer may be a nanoporous polymer layer. In some cases, the second polymer layer may be a macroporous polymer layer. The first and second polymer layers may define a lumen for enclosing a population of cells. In some cases, the device further comprises a third polymer layer. The devices may be used to transplant cells producing therapeutic agents into a subject (e.g., for the treatment of a disease).
B32B 3/26 - Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a particular shape of the outline of the cross-section of a continuous layerLayered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a layer with cavities or internal voids
B32B 7/05 - Interconnection of layers the layers not being connected over the whole surface, e.g. discontinuous connection or patterned connection
C08L 67/04 - Polyesters derived from hydroxy carboxylic acids, e.g. lactones
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61K 9/00 - Medicinal preparations characterised by special physical form
A61P 3/10 - Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor
C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
12.
RESPIRATOR FACE MASKS FOR PROTECTION FROM AIRBORNE PARTICLES
The present disclosure provides a filtration media for filtering one or more airborne particles. The filtration media may comprise a membrane comprising one or more polymeric layers to filter the airborne particles. The filtration media may have high filtration efficiency and high breathability. Additionally, the present disclosure provides devices (e.g., face masks) comprising the filtration media which may be used to filter airborne particles (e.g., bacteria, viruses) and to protect the wearer (e.g., from infection).
The present disclosure provides a filtration media for filtering one or more airborne particles. The filtration media may comprise a membrane comprising one or more polymeric layers to filter the airborne particles. The filtration media may have high filtration efficiency and high breathability. Additionally, the present disclosure provides devices (e.g., face masks) comprising the filtration media which may be used to filter airborne particles (e.g., bacteria, viruses) and to protect the wearer (e.g., from infection).
Disclosed herein are devices for encapsulating biological cells and are suitable to be implanted into a subject. In different aspects of the disclosure, the devices may comprise a plurality of polymer layers. In one aspect, a device comprises a first polymer layer and a second polymer layer. In some cases, the first polymer layer may be a nanoporous polymer layer. In some cases, the second polymer layer may be a macroporous polymer layer. The first and second polymer layers may define a lumen for enclosing a population of cells. The devices may be used to transplant cells producing therapeutic agents into a subject (e.g., for the treatment of a disease).
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
A61M 31/00 - Devices for introducing or retaining media, e.g. remedies, in cavities of the body
15.
CELL ENCAPSULATION DEVICES AND METHODS OF USING SAME
Disclosed herein are devices for encapsulating biological cells and are suitable to be implanted into a subject. In different aspects of the disclosure, the devices may comprise a plurality of polymer layers. In one aspect, a device comprises a first polymer layer and a second polymer layer. In some cases, the first polymer layer may be a nanoporous polymer layer. In some cases, the second polymer layer may be a macroporous polymer layer. The first and second polymer layers may define a lumen for enclosing a population of cells. The devices may be used to transplant cells producing therapeutic agents into a subject (e.g., for the treatment of a disease).
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
