Abstract

The present application describes polypeptides comprising a variant Fc chain that exhibits enhanced accumulation in an organism and methods of producing the same. A method of enhancing accumulation of a protein is also described. The present application also describes polypeptides which specifically bind to intimin on an Escherichia coli cell, including antibodies and antigen-binding fragments thereof, and methods of producing the same. Also described is a method of preventing or reducing colonization of E. coli in the gastrointestinal tract of a mammal. A method of detecting the presence of E. coli in a sample is also described.

IPC Classes  ?

• C07K 16/12 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from bacteria
• A61K 39/40 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum bacterial
• A61P 1/00 - Drugs for disorders of the alimentary tract or the digestive system
• C07K 16/00 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies
• C07K 16/46 - Hybrid immunoglobulins
• C12N 15/13 - Immunoglobulins
• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• C12P 21/08 - Monoclonal antibodies
• G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses

Abstract

A process for isolating at least one target compound, such as manool, geranyl linalool, ethyl guaiacol, eugenol, veratraldehyde, squalene, terpin, cholesterol, beta-sitosterol, campesterol, stigmasterol, stigmastenol and dehydroabietic acid, from biomass, the process including steps of: obtaining a condensate from a recovery evaporator, a reverse osmosis retentate of a condensate of a pulp and paper mill, or both, the condensate, retentate or both being substantially free of higher molecular weight (approximately >1000 Da) cellulose and/or lignin and/or lignin-derived material; optionally pH adjusting and filtering the condensate to collect insoluble material; extracting the condensate, the collected insoluble material, or both, with solid phase extraction (SPE), liquid-liquid extraction or solid-liquid extraction to produce an extract containing the at least one target compound; and optionally purifying the extract containing the at least one target compound by thermal fractionation, chromatographic separation, recrystallization ion exchange, chelation, adsorption/desorption, lyophilization and sublimation or combinations thereof. The method is particularly useful for isolating the target compounds from wastewaters produced in a kraft pulp and paper mill, especially from recovery evaporator condensates produced during the treatment of black liquor.

IPC Classes  ?

• C07C 45/00 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atomsPreparation of chelates of such compounds
• C07C 29/00 - Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
• C07C 41/00 - Preparation of ethersPreparation of compounds having groups, groups or groups
• C07B 63/00 - PurificationSeparation specially adapted for the purpose of recovering organic compoundsStabilisationUse of additives
• B01D 11/04 - Solvent extraction of solutions which are liquid
• C07C 7/12 - Purification, separation or stabilisation of hydrocarbonsUse of additives by adsorption, i.e. purification or separation of hydrocarbons with the aid of solids, e.g. with ion-exchangers
• C07C 29/76 - SeparationPurificationStabilisationUse of additives by physical treatment
• C07C 41/36 - SeparationPurificationStabilisationUse of additives by solid-liquid treatmentSeparationPurificationStabilisationUse of additives by chemisorption
• C07C 45/79 - SeparationPurificationStabilisationUse of additives by solid-liquid treatmentSeparationPurificationStabilisationUse of additives by chemisorption
• B01D 11/00 - Solvent extraction
• C02F 1/00 - Treatment of water, waste water, or sewage
• D21C 11/00 - Regeneration of pulp liquors
• B01D 61/02 - Reverse osmosisHyperfiltration
• B01D 61/00 - Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltrationApparatus, accessories or auxiliary operations specially adapted therefor
• C02F 1/44 - Treatment of water, waste water, or sewage by dialysis, osmosis or reverse osmosis
• C02F 103/28 - Nature of the water, waste water, sewage or sludge to be treated from the processing of plants or parts thereof from the paper or cellulose industry

Abstract

A passive dry deposit (Pas-DD) air sampling device and method for sampling volatile, semi-volatile, or particulate matter in air. The Pas-DD device comprises a top cover plate, a bottom plate connected to and spaced a distance apart from the top cover plate, and at least one sampling media supported by the bottom plate and positioned within the device in an orientation accessible for collecting particles in the environment. The top cover plate and bottom plate may be oriented in parallel, and spaced apart a distanced that can be optimized for air sampling a broad size-range of depositing particles. The passive air sampling device and method disclosed are particularly useful for sampling air in regions where access to electricity is difficult, and for estimating atmospheric loadings of polycyclic aromatic hydrocarbons and other semi-volatile compounds.

IPC Classes  ?

• G01N 1/24 - Suction devices
• G01N 1/22 - Devices for withdrawing samples in the gaseous state
• G01N 1/20 - Devices for withdrawing samples in the liquid or fluent state for flowing or falling materials
• G01N 1/14 - Suction devices, e.g. pumpsEjector devices

Abstract

A passive dry deposit (Pas-DD) air sampling device and method for sampling volatile, semi-volatile, or particulate matter in air. The Pas-DD device comprises a top cover plate, a bottom plate connected to and spaced a distance apart from the top cover plate, and at least one sampling media supported by the bottom plate and positioned within the device in an orientation accessible for collecting particles in the environment. The top cover plate and bottom plate may be oriented in parallel, and spaced apart a distanced that can be optimized for air sampling a broad size-range of depositing particles. The passive air sampling device and method disclosed are particularly useful for sampling air in regions where access to electricity is difficult, and for estimating atmospheric loadings of polycyclic aromatic hydrocarbons and other semi-volatile compounds.

IPC Classes  ?

• G01N 1/22 - Devices for withdrawing samples in the gaseous state

Abstract

Provided are decontamination compositions comprising an ammonium compound, a ferric/ferrocyanide compound, a polyaminocarboxylic acid compound and a polycarboxylic compound. Depending on the mode of application, the compositions can be used as foams, liquids, gels, strippable coatings, mists, or in other forms. Also provided are kits comprising such components in whole or in part and/or a dispersal means for use of the decontamination composition.

IPC Classes  ?

• A62D 3/33 - Processes for making harmful chemical substances harmless, or less harmful, by effecting a chemical change in the substances by reacting with chemical agents by chemically fixing the harmful substance, e.g. by chelation or complexation

Abstract

Provided are decontamination compositions comprising an ammonium compound, a ferric/ferrocyanide compound, a polyaminocarboxylic acid compound and a polycarboxylic compound. Depending on the mode of application, the compositions can be used as foams, liquids, gels, strippable coatings, mists, or in other forms. Also provided are kits comprising such components in whole or in part and/or a dispersal means for use of the decontamination composition.

IPC Classes  ?

• A62D 3/33 - Processes for making harmful chemical substances harmless, or less harmful, by effecting a chemical change in the substances by reacting with chemical agents by chemically fixing the harmful substance, e.g. by chelation or complexation

Abstract

An instrument for obtaining airborne measurements of cloud microphysical parameters. The instrument comprises supporting arms mounted thereon, optics and a detector for measuring the cloud microphysical parameters The supporting arms define an optical path of the instrument and comprise probe tips affixed thereto. The probe tips comprise an outer portion and an inner portion opposite the outer portion. The inner portion of the tips may comprise an angled section having at least one angled surface shaped to deflect particles away from the optical path of the instrument.

IPC Classes  ?

• G01W 1/08 - Adaptations of balloons, missiles, or aircraft for meteorological purposesRadiosondes
• G01N 21/15 - Preventing contamination of the components of the optical system or obstruction of the light path

Abstract

A process for isolating at least one target compound, such as manool, geranyl linalool, ethyl guaiacol, eugenol, veratraldehyde, squalene, terpin, cholesterol, beta-sitosterol, campesterol, stigmasterol, stigmastenol and dehydroabietic acid, from biomass, the process including steps of: obtaining a condensate from a recovery evaporator, a reverse osmosis retentate of a condensate of a pulp and paper mill, or both, the condensate, retentate or both being substantially free of higher molecular weight (approximately >1000 Da) cellulose and/or lignin and/or lignin-derived material; optionally pH adjusting and filtering the condensate to collect insoluble material; extracting the condensate, the collected insoluble material, or both, with solid phase extraction (SPE), liquid-liquid extraction or solid-liquid extraction to produce an extract containing the at least one target compound; and optionally purifying the extract containing the at least one target compound by thermal fractionation, chromatographic separation, recrystallization ion exchange, chelation, adsorption/desorption, lyophilization and sublimation or combinations thereof. The method is particularly useful for isolating the target compounds from wastewaters produced in a kraft pulp and paper mill, especially from recovery evaporator condensates produced during the treatment of black liquor.

IPC Classes  ?

• C07B 63/00 - PurificationSeparation specially adapted for the purpose of recovering organic compoundsStabilisationUse of additives
• B01D 11/04 - Solvent extraction of solutions which are liquid

Abstract

A process for isolating at least one target compound, such as manool, geranyl linalool, ethyl guaiacol, eugenol, veratraldehyde, squalene, terpin, cholesterol, beta-sitosterol, campesterol, stigmasterol, stigmastenol and dehydroabietic acid, from biomass, the process including steps of: obtaining a condensate from a recovery evaporator, a reverse osmosis retentate of a condensate of a pulp and paper mill, or both, the condensate, retentate or both being substantially free of higher molecular weight (approximately >1000 Da) cellulose and/or lignin and/or lignin-derived material; optionally pH adjusting and filtering the condensate to collect insoluble material; extracting the condensate, the collected insoluble material, or both, with solid phase extraction (SPE), liquid-liquid extraction or solid-liquid extraction to produce an extract containing the at least one target compound; and optionally purifying the extract containing the at least one target compound by thermal fractionation, chromatographic separation, recrystallization ion exchange, chelation, adsorption/desorption, lyophilization and sublimation or combinations thereof. The method is particularly useful for isolating the target compounds from wastewaters produced in a kraft pulp and paper mill, especially from recovery evaporator condensates produced during the treatment of black liquor.

IPC Classes  ?

• C07B 63/00 - PurificationSeparation specially adapted for the purpose of recovering organic compoundsStabilisationUse of additives
• B01D 11/04 - Solvent extraction of solutions which are liquid

Abstract

A percussive driving apparatus for an environmental sampling or test device. The driving apparatus comprises a percussion stem (10), a weighted percussion plunger (20) having a longitudinal bore through which the percussion stem (10) is received, the percussion plunger (20) being slidable along a length of the percussion stem (10), a lift element (80) to permit lifting of the percussion plunger (20) along at least a portion of said length of the percussion stem (10), and a percussion pad (30) affixed to the percussion stem (10) at or near a first end thereof. The percussion pad (30) is configured to receive percussive driving force from the percussion plunger (20). The percussion tube (10) is also adapted at the first end to connect to a probe (40) (for example a shielded or unshielded piezometer, or a split spoon sampler, a seepage meter, long term data logging monitoring device, or seismic device) for environmental sampling and/or testing.

IPC Classes  ?

• G01N 1/04 - Devices for withdrawing samples in the solid state, e.g. by cutting
• E21B 49/02 - Testing the nature of borehole wallsFormation testingMethods or apparatus for obtaining samples of soil or well fluids, specially adapted to earth drilling or wells by mechanically taking samples of the soil
• E21B 11/02 - Boring rams
• G01N 1/12 - DippersDredgers

Abstract

A percussive driving apparatus for an environmental sampling or test device. The driving apparatus comprises a percussion stem (10), a weighted percussion plunger (20) having a longitudinal bore through which the percussion stem (10) is received, the percussion plunger (20) being slidable along a length of the percussion stem (10), a lift element (80) to permit lifting of the percussion plunger (20) along at least a portion of said length of the percussion stem (10), and a percussion pad (30) affixed to the percussion stem (10) at or near a first end thereof. The percussion pad (30) is configured to receive percussive driving force from the percussion plunger (20). The percussion tube (10) is also adapted at the first end to connect to a probe (40) (for example a shielded or unshielded piezometer, or a split spoon sampler, a seepage meter, long term data logging monitoring device, or seismic device ) for environmental sampling and/or testing.

IPC Classes  ?

• G01N 1/02 - Devices for withdrawing samples
• G01N 1/10 - Devices for withdrawing samples in the liquid or fluent state
• G01N 1/12 - DippersDredgers
• G01V 9/02 - Determining existence or flow of underground water

Abstract

An instrument for obtaining airborne measurements of cloud microphysical parameters. The instrument comprises supporting arms mounted thereon, optics and a detector for measuring the cloud microphysical parameters The supporting arms define an optical path of the instrument and comprise probe tips affixed thereto. The probe tips comprise an outer portion and an inner portion opposite the outer portion. The inner portion of the tips may comprise an angled section having at least one angled surface shaped to deflect particles away from the optical path of the instrument.

IPC Classes  ?

• G01W 1/00 - Meteorology

Abstract

An instrument for obtaining airborne measurements of cloud microphysical parameters. The instrument comprises supporting arms mounted thereon, optics and a detector for measuring the cloud microphysical parameters The supporting arms define an optical path of the instrument and comprise probe tips affixed thereto. The probe tips comprise an outer portion for deflecting particles away from the optical path of the instrument and an inner portion opposite the outer portion. The outer portion of the tips have a pyramidal section with a centre ridgeline and flat or concave surfaces effective to reduce water shedding and particle shattering during in-flight collection of data.

IPC Classes  ?

• G01W 1/08 - Adaptations of balloons, missiles, or aircraft for meteorological purposesRadiosondes

Abstract

An instrument for obtaining airborne measurements of cloud microphysical parameters. The instrument comprises supporting arms mounted thereon, optics and a detector for measuring the cloud microphysical parameters The supporting arms define an optical path of the instrument and comprise probe tips affixed thereto. The probe tips comprise an outer portion for deflecting particles away from the optical path of the instrument and an inner portion opposite the outer portion. The outer portion of the tips have a pyramidal section with a centre ridgeline and flat or concave surfaces effective to reduce water shedding and particle shattering during in-flight collection of data.

IPC Classes  ?

• G01W 1/00 - Meteorology

Goods & Services

(1) Computer programs and manuals and documentation relating thereto.

Goods & Services

(1) Computer programs and manuals and documentation relating thereto.

Goods & Services

(1) Computer programs.