Panbela Therapeutics, Inc.

United States of America

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        Patent 6
        Trademark 6
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        United States 7
        World 3
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Date
2024 December 2
2024 2
2023 1
2022 1
2021 5
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IPC Class
C07C 215/18 - Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with hydroxy groups and at least two amino groups bound to the carbon skeleton 4
A61K 31/133 - Amines, e.g. amantadine having hydroxy groups, e.g. sphingosine 3
A61P 35/00 - Antineoplastic agents 3
A61K 31/132 - Amines, e.g. amantadine having two or more amino groups, e.g. spermidine, putrescine 2
C07C 213/02 - Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups 2
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Status
Pending 7
Registered / In Force 5

1.

PANBELA

      
Serial Number 98892145
Status Pending
Filing Date 2024-12-09
Owner Panbela Therapeutics, Inc. ()
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Pharmaceutical preparations used for diagnostic and therapeutic purposes in oncology, cancer, and pancreatic cancer; pharmaceutical preparations for oncology; pharmaceutical preparations for the treatment of cancer; pharmaceutical preparations for the treatment of pancreatic cancer

2.

PANBELA

      
Serial Number 98892148
Status Pending
Filing Date 2024-12-09
Owner Panbela Therapeutics, Inc. ()
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Pharmaceutical preparations used for diagnostic and therapeutic purposes in oncology, cancer, and pancreatic cancer; pharmaceutical preparations for oncology; pharmaceutical preparations for the treatment of cancer; pharmaceutical preparations for the treatment of pancreatic cancer

3.

DOSING REGIMENS AND METHODS FOR TREATING CANCER

      
Application Number 17866876
Status Pending
Filing Date 2022-07-18
First Publication Date 2023-03-02
Owner Panbela Therapeutics, Inc. (USA)
Inventor
  • Gagnon, Suzanne
  • Cullen, Michael T.
  • Neenan, Thomas X.
  • Walker, Michael

Abstract

The invention provides methods for treating cancer in a patient comprising administering dosing regimens of (S,S)-(HO)2DEHSPM that unexpectedly reverse or reduce the onset of severe liver toxicity and improve patient safety profiles.

IPC Classes  ?

  • A61K 31/131 - Amines, e.g. amantadine acyclic
  • A61K 31/133 - Amines, e.g. amantadine having hydroxy groups, e.g. sphingosine
  • A61K 31/337 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
  • A61K 31/7068 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
  • A61P 35/00 - Antineoplastic agents

4.

Methods for producing (6S,15S)-3,8,13,18-tetraazaicosane-6,15-diol

      
Application Number 17385156
Grant Number 11591286
Status In Force
Filing Date 2021-07-26
First Publication Date 2022-01-13
Grant Date 2023-02-28
Owner Panbela Therapeutics, Inc. (USA)
Inventor
  • Shanker, P. Sathya
  • Rai U, Sankappa
  • Venghatraghavan, Murali
  • Vengatesan, Selvam
  • Patil, Rahul
  • Bharathkumar, Padavalachandu

Abstract

The present invention provides methods of synthesizing (6S,15S)-3,8,13,18-tetraazaicosane-6,15-diol and salts thereof.

IPC Classes  ?

  • C07C 213/02 - Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
  • C07C 215/18 - Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with hydroxy groups and at least two amino groups bound to the carbon skeleton

5.

DOSING REGIMENS AND METHODS FOR TREATING CANCER

      
Document Number 03164914
Status Pending
Filing Date 2021-01-20
Open to Public Date 2021-07-29
Owner PANBELA THERAPEUTICS, INC. (USA)
Inventor
  • Gagnon, Suzanne
  • Neenan, Thomas X.
  • Cullen, Michael T.
  • Walker, Michael

Abstract

The invention provides methods for treating cancer in a patient comprising administering dosing regimens of (S,S)-(HO)2DEHSPM that unexpectedly reverse or reduce the onset of severe liver toxicity and improve patient safety profiles.

IPC Classes  ?

  • A61K 31/132 - Amines, e.g. amantadine having two or more amino groups, e.g. spermidine, putrescine
  • A61K 31/133 - Amines, e.g. amantadine having hydroxy groups, e.g. sphingosine
  • A61P 35/00 - Antineoplastic agents
  • C07C 215/06 - Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
  • C07C 215/18 - Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with hydroxy groups and at least two amino groups bound to the carbon skeleton

6.

DOSING REGIMENS AND METHODS FOR TREATING CANCER

      
Application Number US2021014112
Publication Number 2021/150559
Status In Force
Filing Date 2021-01-20
Publication Date 2021-07-29
Owner PANBELA THERAPEUTICS, INC. (USA)
Inventor
  • Gagnon, Suzanne
  • Neenan, Thomas, X.
  • Cullen, Michael, T.
  • Walker, Michael

Abstract

The invention provides methods for treating cancer in a patient comprising administering dosing regimens of (S,S)-(HO)2DEHSPM that unexpectedly reverse or reduce the onset of severe liver toxicity and improve patient safety profiles.

IPC Classes  ?

  • A61K 31/132 - Amines, e.g. amantadine having two or more amino groups, e.g. spermidine, putrescine
  • A61K 31/133 - Amines, e.g. amantadine having hydroxy groups, e.g. sphingosine
  • C07C 215/06 - Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
  • C07C 215/18 - Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with hydroxy groups and at least two amino groups bound to the carbon skeleton
  • A61P 35/00 - Antineoplastic agents

7.

Panbela

      
Application Number 1603359
Status Registered
Filing Date 2021-05-12
Registration Date 2021-05-12
Owner Panbela Therapeutics, Inc. (USA)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Pharmaceutical preparations; pharmaceutical preparations for oncology; pharmaceutical preparations for the treatment of cancer; pharmaceutical preparations for the treatment of pancreatic cancer.

8.

PANBELA

      
Application Number 1601295
Status Registered
Filing Date 2021-05-12
Registration Date 2021-05-12
Owner Panbela Therapeutics, Inc. (USA)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Pharmaceutical preparations; pharmaceutical preparations for oncology; pharmaceutical preparations for the treatment of cancer; pharmaceutical preparations for the treatment of pancreatic cancer.

9.

Methods for producing (6S,15S)-3,8,13,18-tetraazaicosane-6,15-diol

      
Application Number 16939500
Grant Number 11098005
Status In Force
Filing Date 2020-07-27
First Publication Date 2021-01-14
Grant Date 2021-08-24
Owner Panbela Therapeutics, Inc. (USA)
Inventor
  • Shanker, P. Sathya
  • Rai U, Sankappa
  • Venghatraghavan, Murali
  • Vengatesan, Selvam
  • Patil, Rahul
  • Bharathkumar, Padavalachandu

Abstract

The present invention provides methods of synthesizing (6S,15S)-3,8,13,18-tetraazaicosane-6,15-diol and salts thereof.

IPC Classes  ?

  • C07C 213/02 - Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
  • C07C 215/18 - Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with hydroxy groups and at least two amino groups bound to the carbon skeleton

10.

PANBELA

      
Serial Number 90318389
Status Pending
Filing Date 2020-11-13
Owner PANBELA THERAPEUTICS, INC. ()
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Pharmaceutical preparations used for diagnostic and therapeutic purposes in oncology, cancer, and pancreatic cancer; pharmaceutical preparations for oncology; pharmaceutical preparations for the treatment of cancer; pharmaceutical preparations for the treatment of pancreatic cancer

11.

PANBELA

      
Serial Number 90318408
Status Pending
Filing Date 2020-11-13
Owner PANBELA THERAPEUTICS, INC. ()
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Pharmaceutical preparations used for diagnostic and therapeutic purposes in oncology, cancer, and pancreatic cancer; pharmaceutical preparations for oncology; pharmaceutical preparations for the treatment of cancer; pharmaceutical preparations for the treatment of pancreatic cancer

12.

METHODS FOR PRODUCING (6S,15S)-3,8,13,18-TETRAAZAICOSANE-6,15-DIOL

      
Document Number 03089388
Status Pending
Filing Date 2019-01-29
Open to Public Date 2019-08-08
Owner PANBELA THERAPEUTICS, INC. (USA)
Inventor
  • Shanker, P. Sathay
  • Rai U, Sankappa
  • Venghatraghavan, Murali
  • Vengatesan, Selvam
  • Patil, Rahul
  • Bharathkumar, Padavalachandu

Abstract

The present invention provides methods of synthesizing (6S,15S)-3,8,13,18-tetraazaicosane-6,15-diol and salts thereof.

IPC Classes  ?

  • C07D 239/70 - Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
  • C07D 403/14 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing three or more hetero rings