Cybrexa 3, Inc.

United States of America

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        World 2
        Canada 1
Date
2024 1
2022 1
2021 3
IPC Class
A61K 47/64 - Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent 5
A61P 35/00 - Antineoplastic agents 3
C07D 265/12 - 1,3-OxazinesHydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems 2
C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof 2
A61K 47/68 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment 1
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Status
Pending 1
Registered / In Force 4
Found results for  patents

1.

Peptide conjugates of microtubule-targeting agents as therapeutics

      
Application Number 18152987
Grant Number 12234212
Status In Force
Filing Date 2023-01-11
First Publication Date 2024-02-29
Grant Date 2025-02-25
Owner Cybrexa 3, Inc. (USA)
Inventor
  • Marshall, Daniel Richard
  • Csengery, Johanna Marie
  • Maguire, Robert John
  • Volkmann, Robert A.

Abstract

The present invention relates to peptide conjugates of microtubule-targeting agents such as maytansinoid derivatives which are useful for the treatment of diseases such as cancer.

IPC Classes  ?

  • C07D 265/12 - 1,3-OxazinesHydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
  • A61K 47/64 - Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent

2.

PEPTIDE CONJUGATES OF THERAPEUTICS

      
Application Number US2022012079
Publication Number 2022/155172
Status In Force
Filing Date 2022-01-12
Publication Date 2022-07-21
Owner CYBREXA 3, INC. (USA)
Inventor
  • Maguire, Robert John
  • Csengery, Johanna Marie

Abstract

The present invention relates to conjugates of therapeutic molecules (e.g., cytotoxic agents) and targeting moieties (e.g., peptides) which are useful in the treatment of diseases such as cancer.

IPC Classes  ?

  • A61K 47/64 - Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
  • A61P 35/00 - Antineoplastic agents
  • C07K 14/215 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Halobacteriaceae (F)

3.

PEPTIDE CONJUGATES OF MICROTUBULE-TARGETING AGENTS AS THERAPEUTICS

      
Application Number US2020041348
Publication Number 2021/007402
Status In Force
Filing Date 2020-07-09
Publication Date 2021-01-14
Owner CYBREXA 3, INC. (USA)
Inventor
  • Marshall, Daniel Richard
  • Csengery, Johanna Marie
  • Maguire, Robert John
  • Volkmann, Robert A.

Abstract

The present invention relates to peptide conjugates of microtubule-targeting agents such as maytansinoid derivatives which are useful for the treatment of diseases such as cancer.

IPC Classes  ?

  • A61K 47/64 - Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
  • A61K 47/68 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
  • A61P 35/00 - Antineoplastic agents
  • C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof

4.

PEPTIDE CONJUGATES OF MICROTUBULE-TARGETING AGENTS AS THERAPEUTICS

      
Document Number 03146385
Status Pending
Filing Date 2020-07-09
Open to Public Date 2021-01-14
Owner CYBREXA 3, INC. (USA)
Inventor
  • Marshall, Daniel Richard
  • Csengery, Johanna Marie
  • Maguire, Robert John
  • Volkmann, Robert A.

Abstract

The present invention relates to peptide conjugates of microtubule-targeting agents such as maytansinoid derivatives which are useful for the treatment of diseases such as cancer.

IPC Classes  ?

  • A61K 47/64 - Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
  • A61P 35/00 - Antineoplastic agents
  • C07K 7/08 - Linear peptides containing only normal peptide links having 12 to 20 amino acids
  • C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof

5.

Peptide conjugates of microtubule-targeting agents as therapeutics

      
Application Number 16924445
Grant Number 11555019
Status In Force
Filing Date 2020-07-09
First Publication Date 2021-01-14
Grant Date 2023-01-17
Owner Cybrexa 3, Inc. (USA)
Inventor
  • Marshall, Daniel Richard
  • Csengery, Johanna Marie
  • Maguire, Robert John
  • Volkmann, Robert A.

Abstract

The present invention relates to peptide conjugates of microtubule-targeting agents such as maytansinoid derivatives which are useful for the treatment of diseases such as cancer.

IPC Classes  ?

  • C07D 265/12 - 1,3-OxazinesHydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
  • A61K 47/64 - Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent