Goods & Services

Chemical products for diagnostic use [scientific]; chemical reagents for use in diagnostic tests, other than for medical or veterinary use; clinical diagnostics, other than for medical or veterinary use; diagnostic chemicals for use in antibiotic susceptibility testing [other than for medical use]; diagnostic kits comprising specimen receptors and reagents for testing for selected pathogens, microbial pathogens, bacteria, viruses, parasites (including protozoa) and fungi (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); diagnostic preparations for research laboratory use; diagnostic preparations for scientific or research use; diagnostic preparations other than for medical or veterinary purposes; diagnostic reagents and preparations, except for medical or veterinary use; diagnostic reagents for in vitro use in biochemistry, clinical chemistry and microbiology; diagnostic reagents for scientific or research use; diagnostic reagents for in-vitro use [other than medical]; diagnostic substances, other than for medical use; diagnostic testing materials, other than for medical use; in-vivo diagnostic reagents for scientific use; nucleic acids for scientific purposes; nucleic acids; reagents for chemical analyses; reagents for medical research; reagents for research purposes; reagents for scientific or medical research use; reagents for scientific purposes, namely, reagents for use in microbial diagnostics; reagents for scientific purposes; reagents for use in diagnostic tests [other than for medical or veterinary purposes]; reagents for use in scientific apparatus for chemical or biological analysis; test reagents [other than for medical use]; testing reagents for scientific use. Buccal swabs for medical use; chemical diagnostic reagents for medical use; chemical preparations for testing samples for medical purposes; chemical reagents for medical or veterinary purposes; chemical test reagents [medical]; clinical diagnostic reagents; clinical medical reagents; diagnostic agents for medical use; diagnostic agents for pharmaceutical use; diagnostic biomarker reagents for medical purposes; diagnostic chemical reagents for medical use; diagnostic preparations and materials, for medical and veterinary purposes; diagnostic preparations for medical purposes used by medical laboratories; diagnostic reagents for medical use; diagnostic substances for medical use; diagnostic testing materials for medical use; in vitro diagnostic preparations for medical use; medical diagnostic reagents and assays for testing of body fluids; medical diagnostic reagents; medical diagnostic test strips; nasopharyngeal swabs for medical use; nucleic acid sequences for medical and veterinary purposes; pharyngeal swabs for medical use; reagents and media for medical and veterinary diagnostic purposes; reagents for medical use; reagents for use in diagnostic tests [for medical purposes]; reagents for use in diagnostic tests [for veterinary purposes]; reagents for use in medical genetic testing; reagents for use in veterinary genetic testing; reagents for use with analyzers [for medical purposes]; swabs for medical use; veterinary diagnostic reagents. Apparatus and instruments for medical research; computer software; diagnostic apparatus for research laboratory use; instruments for diagnosis [for scientific use]; laboratory swabs [laboratory instruments]; quantitative polymerase chain reaction [PCR] instruments for scientific use; real-time polymerase chain reaction [PCR] instruments for scientific use; research laboratory analyzers for measuring, testing and analyzing bodily fluids; scientific apparatus and instruments, namely, cartridges and consumables for laboratory and scientific use; scientific apparatus and instruments; scientific research and laboratory apparatus. Apparatus for carrying-out diagnostic tests for medical purposes; apparatus for DNA and RNA analysis and testing for medical purposes; biological fluid testing instruments for medical diagnostic purposes; bodily fluids testing apparatus; bodily fluids testing equipment; diagnostic apparatus for medical purposes used in medical laboratories; diagnostic apparatus for medical purposes; diagnostic imaging apparatus for medical use; diagnostic instruments for medical use; diagnostic measuring apparatus for medical use; diagnostic testing apparatus for use in molecular diagnostic and analysis [medical]; diagnostic testing apparatus for use in nucleic acid amplification procedures [medical]; diagnostic, examination, and monitoring equipment; medical and veterinary apparatus and instruments; medical devices; medical diagnostic apparatus for medical purposes; medical diagnostic apparatus for testing for pathogens, microbial pathogens, bacteria, viruses, parasites and fungi; medical diagnostic instruments; medical diagnostic saliva pads; medical diagnostic saliva vials; medical diagnostic testing apparatus for detecting and measuring nucleic acid levels; medical instruments for infectious disease testing; medical testing instruments; quantitative polymerase chain reaction [PCR] instruments for medical use; real-time polymerase chain reaction [PCR] instruments for medical use; testing apparatus for medical purposes, namely, cartridges for test samples; testing apparatus for medical purposes; testing instruments for medical diagnostic purposes; testing probes for medical diagnostic purposes; testing probes for medical purposes; tools for medical diagnostics; tools for veterinary diagnostics; ultrasonic medical diagnostic apparatus.

Goods & Services

Chemical products for diagnostic use [scientific]; chemical reagents for use in diagnostic tests, other than for medical or veterinary use; clinical diagnostics, other than for medical or veterinary use; diagnostic chemicals for use in antibiotic susceptibility testing [other than for medical use]; diagnostic kits comprising specimen receptors and reagents for testing for selected pathogens, microbial pathogens, bacteria, viruses, parasites (including protozoa) and fungi (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); diagnostic preparations for research laboratory use; diagnostic preparations for scientific or research use; diagnostic preparations other than for medical or veterinary purposes; diagnostic reagents and preparations, except for medical or veterinary use; diagnostic reagents for in vitro use in biochemistry, clinical chemistry and microbiology; diagnostic reagents for scientific or research use; diagnostic reagents for in-vitro use [other than medical]; diagnostic substances, other than for medical use; diagnostic testing materials, other than for medical use; in-vivo diagnostic reagents for scientific use; nucleic acids for scientific purposes; nucleic acids; reagents for chemical analyses; reagents for medical research; reagents for research purposes; reagents for scientific or medical research use; reagents for scientific purposes, namely, reagents for use in microbial diagnostics; reagents for scientific purposes; reagents for use in diagnostic tests [other than for medical or veterinary purposes]; reagents for use in scientific apparatus for chemical or biological analysis; test reagents [other than for medical use]; testing reagents for scientific use. Buccal swabs for medical use; chemical diagnostic reagents for medical use; chemical preparations for testing samples for medical purposes; chemical reagents for medical or veterinary purposes; chemical test reagents [medical]; clinical diagnostic reagents; clinical medical reagents; diagnostic agents for medical use; diagnostic agents for pharmaceutical use; diagnostic biomarker reagents for medical purposes; diagnostic chemical reagents for medical use; diagnostic preparations and materials, for medical and veterinary purposes; diagnostic preparations for medical purposes used by medical laboratories; diagnostic reagents for medical use; diagnostic substances for medical use; diagnostic testing materials for medical use; in vitro diagnostic preparations for medical use; medical diagnostic reagents and assays for testing of body fluids; medical diagnostic reagents; medical diagnostic test strips; nasopharyngeal swabs for medical use; nucleic acid sequences for medical and veterinary purposes; pharyngeal swabs for medical use; reagents and media for medical and veterinary diagnostic purposes; reagents for medical use; reagents for use in diagnostic tests [for medical purposes]; reagents for use in diagnostic tests [for veterinary purposes]; reagents for use in medical genetic testing; reagents for use in veterinary genetic testing; reagents for use with analyzers [for medical purposes]; swabs for medical use; veterinary diagnostic reagents. Apparatus and instruments for medical research; computer software; diagnostic apparatus for research laboratory use; instruments for diagnosis [for scientific use]; laboratory swabs [laboratory instruments]; quantitative polymerase chain reaction [PCR] instruments for scientific use; real-time polymerase chain reaction [PCR] instruments for scientific use; research laboratory analyzers for measuring, testing and analyzing bodily fluids; scientific apparatus and instruments, namely, cartridges and consumables for laboratory and scientific use; scientific apparatus and instruments; scientific research and laboratory apparatus. Apparatus for carrying-out diagnostic tests for medical purposes; apparatus for DNA and RNA analysis and testing for medical purposes; biological fluid testing instruments for medical diagnostic purposes; bodily fluids testing apparatus; bodily fluids testing equipment; diagnostic apparatus for medical purposes used in medical laboratories; diagnostic apparatus for medical purposes; diagnostic imaging apparatus for medical use; diagnostic instruments for medical use; diagnostic measuring apparatus for medical use; diagnostic testing apparatus for use in molecular diagnostic and analysis [medical]; diagnostic testing apparatus for use in nucleic acid amplification procedures [medical]; diagnostic, examination, and monitoring equipment; medical and veterinary apparatus and instruments; medical devices; medical diagnostic apparatus for medical purposes; medical diagnostic apparatus for testing for pathogens, microbial pathogens, bacteria, viruses, parasites and fungi; medical diagnostic instruments; medical diagnostic saliva pads; medical diagnostic saliva vials; medical diagnostic testing apparatus for detecting and measuring nucleic acid levels; medical instruments for infectious disease testing; medical testing instruments; quantitative polymerase chain reaction [PCR] instruments for medical use; real-time polymerase chain reaction [PCR] instruments for medical use; testing apparatus for medical purposes, namely, cartridges for test samples; testing apparatus for medical purposes; testing instruments for medical diagnostic purposes; testing probes for medical diagnostic purposes; testing probes for medical purposes; tools for medical diagnostics; tools for veterinary diagnostics; ultrasonic medical diagnostic apparatus.

Goods & Services

Chemical products for diagnostic use [scientific]; chemical reagents for use in diagnostic tests, other than for medical or veterinary use; clinical diagnostics, other than for medical or veterinary use; diagnostic chemicals for use in antibiotic susceptibility testing [other than for medical use]; diagnostic kits comprising specimen receptors and reagents for testing for selected pathogens, microbial pathogens, bacteria, viruses, parasites (including protozoa) and fungi (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); diagnostic preparations for research laboratory use; diagnostic preparations for scientific or research use; diagnostic preparations other than for medical or veterinary purposes; diagnostic reagents and preparations, except for medical or veterinary use; diagnostic reagents for in vitro use in biochemistry, clinical chemistry and microbiology; diagnostic reagents for scientific or research use; diagnostic reagents for in-vitro use [other than medical]; diagnostic substances, other than for medical use; diagnostic testing materials, other than for medical use; in-vivo diagnostic reagents for scientific use; nucleic acids for scientific purposes; nucleic acids; reagents for chemical analyses; reagents for medical research; reagents for research purposes; reagents for scientific or medical research use; reagents for scientific purposes, namely, reagents for use in microbial diagnostics; reagents for scientific purposes; reagents for use in diagnostic tests [other than for medical or veterinary purposes]; reagents for use in scientific apparatus for chemical or biological analysis; test reagents [other than for medical use]; testing reagents for scientific use. Buccal swabs for medical use; chemical diagnostic reagents for medical use; chemical preparations for testing samples for medical purposes; chemical reagents for medical or veterinary purposes; chemical test reagents [medical]; clinical diagnostic reagents; clinical medical reagents; diagnostic agents for medical use; diagnostic agents for pharmaceutical use; diagnostic biomarker reagents for medical purposes; diagnostic chemical reagents for medical use; diagnostic preparations and materials, for medical and veterinary purposes; diagnostic preparations for medical purposes used by medical laboratories; diagnostic reagents for medical use; diagnostic substances for medical use; diagnostic testing materials for medical use; in vitro diagnostic preparations for medical use; medical diagnostic reagents and assays for testing of body fluids; medical diagnostic reagents; medical diagnostic test strips; nasopharyngeal swabs for medical use; nucleic acid sequences for medical and veterinary purposes; pharyngeal swabs for medical use; reagents and media for medical and veterinary diagnostic purposes; reagents for medical use; reagents for use in diagnostic tests [for medical purposes]; reagents for use in diagnostic tests [for veterinary purposes]; reagents for use in medical genetic testing; reagents for use in veterinary genetic testing; reagents for use with analyzers [for medical purposes]; swabs for medical use; veterinary diagnostic reagents. Apparatus and instruments for medical research; computer software; diagnostic apparatus for research laboratory use; instruments for diagnosis [for scientific use]; laboratory swabs [laboratory instruments]; quantitative polymerase chain reaction [PCR] instruments for scientific use; real-time polymerase chain reaction [PCR] instruments for scientific use; research laboratory analyzers for measuring, testing and analyzing bodily fluids; scientific apparatus and instruments, namely, cartridges and consumables for laboratory and scientific use; scientific apparatus and instruments; scientific research and laboratory apparatus. Apparatus for carrying-out diagnostic tests for medical purposes; apparatus for DNA and RNA analysis and testing for medical purposes; biological fluid testing instruments for medical diagnostic purposes; bodily fluids testing apparatus; bodily fluids testing equipment; diagnostic apparatus for medical purposes used in medical laboratories; diagnostic apparatus for medical purposes; diagnostic imaging apparatus for medical use; diagnostic instruments for medical use; diagnostic measuring apparatus for medical use; diagnostic testing apparatus for use in molecular diagnostic and analysis [medical]; diagnostic testing apparatus for use in nucleic acid amplification procedures [medical]; diagnostic, examination, and monitoring equipment; medical and veterinary apparatus and instruments; medical devices; medical diagnostic apparatus for medical purposes; medical diagnostic apparatus for testing for pathogens, microbial pathogens, bacteria, viruses, parasites and fungi; medical diagnostic instruments; medical diagnostic saliva pads; medical diagnostic saliva vials; medical diagnostic testing apparatus for detecting and measuring nucleic acid levels; medical instruments for infectious disease testing; medical testing instruments; quantitative polymerase chain reaction [PCR] instruments for medical use; real-time polymerase chain reaction [PCR] instruments for medical use; testing apparatus for medical purposes, namely, cartridges for test samples; testing apparatus for medical purposes; testing instruments for medical diagnostic purposes; testing probes for medical diagnostic purposes; testing probes for medical purposes; tools for medical diagnostics; tools for veterinary diagnostics; ultrasonic medical diagnostic apparatus.

Goods & Services

Chemical products for diagnostic use [scientific]; chemical reagents for use in diagnostic tests, other than for medical or veterinary use; clinical diagnostics, other than for medical or veterinary use; diagnostic chemicals for use in antibiotic susceptibility testing [other than for medical use]; diagnostic kits comprising specimen receptors and reagents for testing for selected pathogens, microbial pathogens, bacteria, viruses, parasites (including protozoa) and fungi (term considered too vague by the International Bureau pursuant to Rule 13 (2) (b) of the Regulations); diagnostic preparations for research laboratory use; diagnostic preparations for scientific or research use; diagnostic preparations other than for medical or veterinary purposes; diagnostic reagents and preparations, except for medical or veterinary use; diagnostic reagents for in vitro use in biochemistry, clinical chemistry and microbiology; diagnostic reagents for scientific or research use; diagnostic reagents for in-vitro use [other than medical]; diagnostic substances, other than for medical use; diagnostic testing materials, other than for medical use; in-vivo diagnostic reagents for scientific use; nucleic acids for scientific purposes; nucleic acids; reagents for chemical analyses; reagents for medical research; reagents for research purposes; reagents for scientific or medical research use; reagents for scientific purposes, namely, reagents for use in microbial diagnostics; reagents for scientific purposes; reagents for use in diagnostic tests [other than for medical or veterinary purposes]; reagents for use in scientific apparatus for chemical or biological analysis; test reagents [other than for medical use]; testing reagents for scientific use. Buccal swabs for medical use; chemical diagnostic reagents for medical use; chemical preparations for testing samples for medical purposes; chemical reagents for medical or veterinary purposes; chemical test reagents [medical]; clinical diagnostic reagents; clinical medical reagents; diagnostic agents for medical use; diagnostic agents for pharmaceutical use; diagnostic biomarker reagents for medical purposes; diagnostic chemical reagents for medical use; diagnostic preparations and materials, for medical and veterinary purposes; diagnostic preparations for medical purposes used by medical laboratories; diagnostic reagents for medical use; diagnostic substances for medical use; diagnostic testing materials for medical use; in vitro diagnostic preparations for medical use; medical diagnostic reagents and assays for testing of body fluids; medical diagnostic reagents; medical diagnostic test strips; nasopharyngeal swabs for medical use; nucleic acid sequences for medical and veterinary purposes; pharyngeal swabs for medical use; reagents and media for medical and veterinary diagnostic purposes; reagents for medical use; reagents for use in diagnostic tests [for medical purposes]; reagents for use in diagnostic tests [for veterinary purposes]; reagents for use in medical genetic testing; reagents for use in veterinary genetic testing; reagents for use with analyzers [for medical purposes]; swabs for medical use; veterinary diagnostic reagents. Apparatus and instruments for medical research; computer software; diagnostic apparatus for research laboratory use; instruments for diagnosis [for scientific use]; laboratory swabs [laboratory instruments]; quantitative polymerase chain reaction [PCR] instruments for scientific use; real-time polymerase chain reaction [PCR] instruments for scientific use; research laboratory analyzers for measuring, testing and analyzing bodily fluids; scientific apparatus and instruments, namely, cartridges and consumables for laboratory and scientific use; scientific apparatus and instruments; scientific research and laboratory apparatus. Apparatus for carrying-out diagnostic tests for medical purposes; apparatus for DNA and RNA analysis and testing for medical purposes; biological fluid testing instruments for medical diagnostic purposes; bodily fluids testing apparatus; bodily fluids testing equipment; diagnostic apparatus for medical purposes used in medical laboratories; diagnostic apparatus for medical purposes; diagnostic imaging apparatus for medical use; diagnostic instruments for medical use; diagnostic measuring apparatus for medical use; diagnostic testing apparatus for use in molecular diagnostic and analysis [medical]; diagnostic testing apparatus for use in nucleic acid amplification procedures [medical]; diagnostic, examination, and monitoring equipment; medical and veterinary apparatus and instruments; medical devices; medical diagnostic apparatus for medical purposes; medical diagnostic apparatus for testing for pathogens, microbial pathogens, bacteria, viruses, parasites and fungi; medical diagnostic instruments; medical diagnostic saliva pads; medical diagnostic saliva vials; medical diagnostic testing apparatus for detecting and measuring nucleic acid levels; medical instruments for infectious disease testing; medical testing instruments; quantitative polymerase chain reaction [PCR] instruments for medical use; real-time polymerase chain reaction [PCR] instruments for medical use; testing apparatus for medical purposes, namely, cartridges for test samples; testing apparatus for medical purposes; testing instruments for medical diagnostic purposes; testing probes for medical diagnostic purposes; testing probes for medical purposes; tools for medical diagnostics; tools for veterinary diagnostics; ultrasonic medical diagnostic apparatus.

Abstract

Cartridges, e.g., microfluidic cartridges with a component-free valve include a substrate, a fluidic channel formed in a surface of the substrate, and a component-free valve within the fluidic channel including a blockage area of the substrate that separates a first portion of the fluidic channel from a second portion of the fluidic channel, and a flexible film bonded to the surface of the substrate along the fluidic channel and around the blockage area, but unbonded in an area that encloses the blockage area and a section of the first and second portions of the fluidic channel. When the film of these cartridges is pressed against a surface of the blockage area, the component-free valve is closed, and when the unbonded flexible film is not pressed against the blockage area, the component-free valve is open, enabling fluid flow from the first portion of the fluidic channel to the second portion of the fluidic channel.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• F16K 99/00 - Subject matter not provided for in other groups of this subclass

Abstract

A reaction cartridge system is described herein. In some embodiments, a reaction cartridge, includes a cap that contains a lyophilized reagent cake within the cap, and a stirrer element encapsulated within the lyophilized reagent cake.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• B01F 33/452 - Magnetic mixersMixers with magnetically driven stirrers using independent floating stirring elements
• B01F 101/23 - Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials

Abstract

Testing devices for testing a swab sample, the devices including a swab chamber configured to receive the swab sample; an elution source configured to supply an eluent to the swab chamber, wherein the eluent is a liquid that interacts with the swab sample to produce an eluate indicative of a property of the swab sample; a discard channel configured to receive a first portion of the eluate from the swab chamber to be discarded; an analysis channel configured to receive a second portion of the eluate from the swab chamber to be processed; and a channel selector configured to selectively direct the first portion into the discard channel and the second portion into the analysis channel.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers

Abstract

A reaction cartridge system is described herein. In some embodiments, a reaction cartridge, includes a cap that contains a lyophilized reagent cake within the cap, and a stirrer element encapsulated within the lyophilized reagent cake.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• B01F 33/05 - Mixers using radiation, e.g. magnetic fields or microwaves to mix the material
• B01L 7/00 - Heating or cooling apparatusHeat insulating devices

Abstract

V.

IPC Classes  ?

• B01L 7/00 - Heating or cooling apparatusHeat insulating devices
• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• C12Q 1/6806 - Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
• C12Q 1/686 - Polymerase chain reaction [PCR]

Abstract

Systems for nucleic acid amplification testing are provided. The systems comprise a consumable amplification module and a reader module for receiving the amplification module. The amplification module comprises: a reactor vessel for containing a test sample; a heater comprising a heater element in thermal contact with the reactor vessel and controllable to add heat to the reactor vessel so as to heat the test sample; a temperature sensor for determining the temperature of at least one of the heater element and the test sample; and a heat sink or a heat spreader in thermal contact with the heater. The reader module comprises: a heater controller for selectively controlling the heater element between an on condition and an off condition in response to the determined temperature of the heater element and/or test sample; and an electrical heater interface for connecting the heater controller and the heater. The system comprises a heat sink for subtracting heat from the reactor vessel so as to cool the test sample. The amplification module may comprise the heat sink. The receiver module may comprise the heat sink and a thermal interface, and the amplification module may comprise the heat spreader for thermal contact with the thermal interface.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• B01L 7/00 - Heating or cooling apparatusHeat insulating devices

Abstract

A heater for thermocycling to carry out PCR amplification. The heater comprises: a thermal diffusion layer having a reaction surface for transferring heat to a reaction cell; a heater track support layer having a back surface for cooling; an electrically conductive main heater track supported between the heater track support layer and the thermal diffusion layer; and four-terminal electrical contacts to the main heater track adapted to provide electrical connection for driving the main heater track and simultaneously sensing a resistance of the main heater track. The lateral dimensions of the reaction surface are greater than a thickness H of the heater, such that reaction surface area A>H2.

IPC Classes  ?

• B01L 7/00 - Heating or cooling apparatusHeat insulating devices

Abstract

Testing devices for testing a swab sample, the devices including a swab chamber configured to receive the swab sample; an elution source configured to supply an eluent to the swab chamber, wherein the eluent is a liquid that interacts with the swab sample to produce an eluate indicative of a property of the swab sample; a discard channel configured to receive a first portion of the eluate from the swab chamber to be discarded; an analysis channel configured to receive a second portion of the eluate from the swab chamber to be processed; and a channel selector configured to selectively direct the first portion into the discard channel and the second portion into the analysis channel.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• B01L 7/00 - Heating or cooling apparatusHeat insulating devices
• G01N 1/02 - Devices for withdrawing samples

Abstract

v.

IPC Classes  ?

• B01L 7/00 - Heating or cooling apparatusHeat insulating devices
• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• C12Q 1/6806 - Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
• C12Q 1/686 - Polymerase chain reaction [PCR]

Abstract

A heater for thermocycling to carry out PCR amplification. The heater comprises: a thermal diffusion layer having a reaction surface for transferring heat to a reaction cell; a heater track support layer having a back surface for cooling; an electrically conductive main heater track supported between the heater track support layer and the thermal diffusion layer; and four-terminal electrical contacts to the main heater track adapted to provide electrical connection for driving the main heater track and simultaneously sensing a resistance of the main heater track. The lateral dimensions of the reaction surface are greater than a thickness H of the heater, such that reaction surface area A > H 2 .

IPC Classes  ?

• B01L 7/00 - Heating or cooling apparatusHeat insulating devices
• C12M 1/38 - Temperature-responsive control
• C12M 1/40 - Apparatus specially designed for the use of free, immobilised, or carrier-bound enzymes, e.g. apparatus containing a fluidised bed of immobilised enzymes
• C12Q 1/686 - Polymerase chain reaction [PCR]
• C12Q 3/00 - Condition-responsive control processes

Abstract

Systems for nucleic acid amplification testing are provided. The systems comprise a consumable amplification module and a reader module for receiving the amplification module. The amplification module comprises: a reactor vessel for containing a test sample; a heater comprising a heater element in thermal contact with the reactor vessel and controllable to add heat to the reactor vessel so as to heat the test sample; a temperature sensor for determining the temperature of at least one of the heater element and the test sample; and a heat sink or a heat spreader in thermal contact with the heater. The reader module comprises: a heater controller for selectively controlling the heater element between an on condition and an off condition in response to the determined temperature of the heater element and/or test sample; and an electrical heater interface for connecting the heater controller and the heater. The system comprises a heat sink for subtracting heat from the reactor vessel so as to cool the test sample. The amplification module may comprise the heat sink. The receiver module may comprise the heat sink and a thermal interface, and the amplification module may comprise the heat spreader for thermal contact with the thermal interface.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• B01L 7/00 - Heating or cooling apparatusHeat insulating devices

Abstract

HA > H22.

IPC Classes  ?

• B01L 7/00 - Heating or cooling apparatusHeat insulating devices

Abstract

Systems for nucleic acid amplification testing are provided. The systems comprise a consumable amplification module and a reader module for receiving the amplification module. The amplification module comprises: a reactor vessel for containing a test sample; a heater comprising a heater element in thermal contact with the reactor vessel and controllable to add heat to the reactor vessel so as to heat the test sample; a temperature sensor for determining the temperature of at least one of the heater element and the test sample; and a heat sink or a heat spreader in thermal contact with the heater. The reader module comprises: a heater controller for selectively controlling the heater element between an on condition and an off condition in response to the determined temperature of the heater element and/or test sample; and an electrical heater interface for connecting the heater controller and the heater. The system comprises a heat sink for subtracting heat from the reactor vessel so as to cool the test sample. The amplification module may comprise the heat sink. The receiver module may comprise the heat sink and a thermal interface, and the amplification module may comprise the heat spreader for thermal contact with the thermal interface.

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• B01L 7/00 - Heating or cooling apparatusHeat insulating devices
• C12M 1/34 - Measuring or testing with condition measuring or sensing means, e.g. colony counters
• C12M 1/38 - Temperature-responsive control
• C12Q 1/6844 - Nucleic acid amplification reactions

Abstract

There is described a variable-temperature reactor for hosting a predetermined reaction therein. The reactor comprises a reaction cell, a heater, and a heat sink. The reaction cell has a reaction volume with thickness H v and width W v where W v > 4 H v and is defined by faces with one of the larger area faces of the reaction volume being bounded by an outer wall with thickness H w . The heater is in contact with the said outer wall. The heater comprises a heat-generating heater element located on the face closer to the reaction volume and a heater support on the opposite face. The heater support is in contact with a heat sink, such that the heater support provides a thermal resistance R T between the heater element and the heat sink. The reactor, when filled with reagents having thermal diffusion coefficient D v has a diffusion time t v , in the thickness direction, t v = H v 2 / D v . t v is less than the reaction time constant t R . The outer wall has a thermal diffusion coefficient D w and has a thermal diffusion time t w = H w 2 I D w < t v .

IPC Classes  ?

• B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
• B01L 7/00 - Heating or cooling apparatusHeat insulating devices