A tool for using conventional ultrasound techniques for renal fibrosis assessment, particularly in cases of chronic kidney disease. Patient parameters such as age are combined with ultrasonically determined parameters both morphological (e.g. renal length) and hemodynamic (e.g. end-diastolic velocity of circulation in the interlobal renal artery) to evaluate the risk of a patient displaying moderate-to-severe renal fibrosis over a baseline risk. Additional and/or substitute parameters are also described.
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
2.
METHODS FOR FACILITATING THE DIFFERENTIATION OF INDUCED PLURIPOTENT STEM CELLS INTO RETINAL GANGLION CELLS
Centre for Eye and Vision Research Limited (Hong Kong)
The Hong Kong Polytechnic University (Hong Kong)
Inventor
Huang, Chien-Ling
Yip, Shea Ping
Wong, Ka-Hing
Wong, Nonthaphat
Sun, Jiahong
Jiang, Zhiwei
Abstract
A method for differentiating induced pluripotent stem cells (iPSCs) into retinal ganglion cells (RGCs) involves deleting a sequence encoding LNC000093 long non-coding RNA from the iPSC genome, culturing the modified iPSCs to generate colonies, and dissociating these colonies to form embryoid bodies. The embryoid bodies are transferred to a first plate to induce neural rosette formation. The neural rosettes are detached and cultured in suspension to develop into neurospheres, which are subsequently transferred to a second plate to promote differentiation into RGCs.
C12N 15/11 - DNA or RNA fragmentsModified forms thereof
C12N 15/90 - Stable introduction of foreign DNA into chromosome
C12Q 1/6874 - Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation [SBH]
C12Q 1/6881 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
3.
AUTONOMOUS DRIVING SYSTEM WITH PRIORITIZING ENERGY-SAVING CONSIDERATIONS
An autonomous driving system having a three-layer framework to optimize energy consumption in autonomous driving by utilizing the driving trajectory of human drivers. The first layer involves smoothing out the driving path to reduce its curvature, thereby avoiding sudden changes in acceleration and velocity caused by abrupt path changes. The second layer is a trajectory optimization stage, where a relationship between speed and time in the human driving trajectory is assigned to the smoothed path. The acceleration is calculated at each moment based on the motor torque-rotational speed efficiency diagram and the corresponding output efficiency of the motor. A best efficiency interval is then determined based on a reference motor efficiency, which is then converted into an optimal speed and acceleration interval of each of the wheels. On the smooth path, the optimal speed and acceleration interval are jointly optimized to obtain the best driving trajectory in order to ensure that the motor operates in the high-efficiency interval. In the third layer, the generated optimal trajectory is combined with the model predictive control (MPC) method to generate the optimal steering angle to achieve accurate trajectory tracking.
B60W 60/00 - Drive control systems specially adapted for autonomous road vehicles
B60W 20/11 - Controlling the power contribution of each of the prime movers to meet required power demand using model predictive control [MPC] strategies, i.e. control methods based on models predicting performance
B60W 30/182 - Selecting between different operative modes, e.g. comfort and performance modes
B60W 50/00 - Details of control systems for road vehicle drive control not related to the control of a particular sub-unit
4.
System and Method of Power MOSFET Diagnostic and Lifetime Estimation Using AI Algorithm
Centre for Advances in Reliability and Safety Limited (Hong Kong)
The Hong Kong Polytechnic University (Hong Kong)
Inventor
Loo, Ka Hong
Lee, Hiu Hung
Lu, Chang
Abstract
Disclosed is a power metal-oxide-semiconductor field-effect transistor (MOSFET) diagnostic and lifetime estimation system and method, including the steps of: acquiring degradation data by conducting a degradation test; measuring potential failure precursors to provide early warning of failure; inspecting and diagnosing health condition of internal structure of the power MOSFET device using thermal transient measurement and scanning acoustic microscopy (SAM) images; repeating power cycling test and the measurements of potential failure precursors until the precursors reach a corresponding failure threshold; and estimating remaining lifetime of the power MOSFET device using an artificial intelligence (AI) algorithm.
Composites of metal-organic framework particles and bacterial cellulose, methods of making the composites, and methods of using the composites in the hydrolysis of organic compounds are provided. The composites, which are aerogels comprising metal-organic framework particles embedded in a bacterial cellulose nanofiber network, are fabricated using a microbial synthesis strategy in which bacterial cellulose nanofiber is biosynthesized using a cellulose-producing bacteria in a fermentation medium in which metal-organic framework particles are dispersed.
A method of controlling a pneumatic muscle device through an electromyographic signal including: obtaining electromyographic signals currently generated by each of the target muscles of the wearer of the pneumatic muscle device; determining a behavior classification of the wearer of the pneumatic muscle device according to all of the electromyographic signals and a preset neural network model, and the neural network model is trained and obtained according to historical electromyographic signals generated by each of the target muscles; determining a driving amount corresponding to each of the target muscles according to the behavior classification of the wearer of the pneumatic muscle device; and driving the simulated muscles corresponding to each of the target muscles according to the driving amount corresponding to each of target muscles.
Multifunctional and regenerable N-chlorine based biocidal and detoxifying metal-organic frameworks are provided. Chloramine functional groups on the organic linkers of the metal-organic frameworks act as chlorine carriers. Pathogens or harmful organic compounds that come into contact with the metal-organic frameworks in the presence of water are rendered inactive by reactions with the active chlorine. The metal-organic frameworks can be incorporated into textiles used to make protective wearable articles.
C07F 7/00 - Compounds containing elements of Groups 4 or 14 of the Periodic Table
A01N 55/02 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing elements other than carbon, hydrogen, halogen, oxygen, nitrogen and sulfur containing metal atoms
A41D 13/11 - Protective face masks, e.g. for surgical use, or for use in foul atmospheres
Centre for Eye and Vision Research Limited (Hong Kong)
The Hong Kong Polytechnic University (Hong Kong)
Inventor
Li, Rong
Lin, Bin
Abstract
A pharmaceutical composition for treating retinal degeneration is provided. Particularly, the pharmaceutical composition includes a tropomyosin 1 (TPM1) inhibitor and is further enriched with pharmaceutically acceptable additives. In addition, the pharmaceutical formulation is configured to suppress and/or knock down the expression and/or activity of TPM1, thereby addressing the molecular factors associated with retinal degeneration.
Centre for Eye and Vision Research Limited (Hong Kong)
The Hong Kong Polytechnic University (Hong Kong)
Inventor
Lam, Chuen
Sze, Ying Hon
Tse, Yan Yin
Abstract
A pharmacologic treatment of refractive disorders, specifically myopia or hyperopia, by targeting the PPAR signaling pathway using a PPARγ agonist without any binding to PPARα. It is demonstrated that the PPARγ agonist modulates ocular growth through therapeutic intervention at the protein level of the PPAR signaling pathway. The effectiveness of the PPARγ agonist in regulating the PPAR signaling pathway and its associated proteins, as evidenced by experiments using a lens-induced myopia (LIM) animal model. More particularly, it is also demonstrated that the pharmacological reduction of myopic eye growth in terms of biometrics with dosage effect through the administration of the PPARγ agonist.
A61K 31/4439 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A61P 27/10 - Ophthalmic agents for accommodation disorders, e.g. myopia
10.
COMBINED TESTBENCH TYPE AND WALKING TYPE COMPLIANT EXOSKELETON SYSTEM
A combined testbench type and walking type compliant exoskeleton system quickly and efficiently converts from a fixed testbench configuration to a mobile orthosis configuration. The addition of a series elastic actuator allows the combined testbench type and walking type compliant exoskeleton system to have a higher level of safe physical human-robot interaction and safety for users with spasticity or tremor. Alternate embodiments incorporating a combination of the rigid and compliant joints, allowing the combination of a swing test and enhancement of a user's strength for walking or other movement is also disclosed.
CENTRE FOR EYE AND VISION RESEARCH LIMITED (Hong Kong)
THE HONG KONG POLYTECHNIC UNIVERSITY (Hong Kong)
Inventor
Wong, Man-Sau
Wong, Ka-Ying
Liu, Juewen
Liu, Yibo
Abstract
Provided herein are aptamer functionalized liposomes for delivery of ocular drug for eye diseases (such as dry eye disease), products comprising the same and method for preventing and/or treating eye diseases using the same. The aptamer functionalized liposomes, product and method of the present application can be used to effectively delivering ocular drug with extended retention time and high protective effect.
A61K 47/54 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
An algorithm-driven digital ultraviolet (UV) lithography (DUL) method and apparatus used to fabricate high-quality optical waveguide and many other kinds of high-resolution microstructures without the use of a photomask. Instead of the use of an actual photomask, a virtual mask based on a spatial light modulator is used. The DUL method and apparatus can compensate for a proximity effect caused by light scattering and make the exposure adaptive to a nonlinear response curve of a photoresist, in which an exposure dose-map is created based on the bitmap of a designed pattern together with the optimization parameters determined by system configuration and the photoresist. To fabricate large-area patterns, a plurality of sliced exposure dose-submaps with transition zones that can depress the stitching error caused by mechanical mispositioning are generated for digital lithographic exposure process.
Lithium-sulfur (Li—S) batteries using unconventional-phase transition metal dichalcogenides (TMDs), such as 1T′-WS2, as the functional layer on the separator. The unique atomic structure of 1T′-WS2 facilitates the strong immobilization and excellent catalytic ability in the conversion of polysulfide intermediates during cycling. Furthermore, the self-assembling of 1T′-WS2 greatly decreases the internal porosity, minimizing the uptake of electrolyte, which can further guarantee the performance of the battery under lean electrolyte conditions. As a result, a cell based on the 1T′-WS2 shows improved performances under high sulfur loading and lean electrolyte conditions. A cell with 12 mg cm−2 mass loading of S with only 25% oversized Li metal anode can deliver specific energy of at least 400 Wh kg−1 and 820 Wh L−1, which is among the best of reported Li—S batteries.
Centre for Eye and Vision Research Limited (Hong Kong)
The Hong Kong Polytechnic University (Hong Kong)
Inventor
Thompson, Benjamin Simon
To, Chi Ho
Tse, Yan Yin
Chun, Ka Man
De Lestrange-Anginieur, Elie Aymard Jonathan
Abstract
Methods, systems and devices for preventing and/or retarding myopia onset and/or progression are provided. Particularly, the system for preventing and/or retarding myopia onset and/or progression including an eye tracker, a display, a controller, and a dynamic blurring filter for the visual content on the display. The display is first presented to a subject, then the eye tracker is employed to detect the movement and the location of the subject's eyes and generate a tracking signal. The tracking signal is further processed by the controller to determine a gaze point of the subject's eye on the display. Based on the gaze point, a dynamic blurring filter is created and applied onto the display.
Centre for Eye and Vision Research Limited (Hong Kong)
The Hong Kong Polytechnic University (Hong Kong)
Inventor
Zaw, Myo Win
Hopkins, William Scott
Cheong, Ming Yan, Allen
Abstract
A machine learning system predicts a physicochemical property (e.g., lipophilicity) of candidate small molecules for pharmaceuticals. A machine learning model is constructed that is trained from a database of small molecule physicochemical properties including known lipophilicity and known retention time in a liquid chromatography column to create a learned association between lipophilicity and liquid chromatography retention time. A candidate small molecule having unknown lipophilicity and unknown retention time is applied to a liquid chromatography column. The retention time of the candidate small molecule in the liquid chromatography column is measured. The measured retention time in the liquid chromatography column is applied to the machine learning model to obtain lipophilicity for the candidate small molecule. One or more candidate small molecules having a lipophilicity value from approximately 1 to approximately 3 are selected from the machine learning model. The identified candidate small molecules are tested for pharmaceutical activity.
A spectacle lens can inhibit ametropia of the eyes and ensure full visibility. The spectacle lens comprises: first refraction areas and second refraction areas. Each first refraction area has a first refraction force that may be based on a prescription for correcting the ametropia of the eyes. Each second refraction area has a refraction force different from the first refraction force and may function to focus images on the positions except the retina of the eyes, to inhibit the development of the ametropia. Near the central part of the lens, the second refraction areas form a plurality of independent island-shaped areas, and the first refraction areas form the areas beyond the areas of the second refraction areas.
A method of preparing antimicrobial 3D-printed material with antimicrobial agents integrated with the 3D-printed material. The 3D-printed material fabricated with the method of the present disclosure includes antimicrobial agent (s) fully integrated throughout the product and display antimicrobial effect throughout the product, which is resistant to daily wear and tear.
A medical device that includes a carrier member, one or more operative components disposed in the carrier member, an optical fiber at least partly disposed in the carrier member, and at least one fiber Bragg grating (FBG) sensor array associated with the optical fiber and disposed in the carrier member. The carrier member includes an insertion end and side walls that contact the subject's body during positioning of the carrier member in the subject's body. The at least one FBG sensor array measures contact forces at one or both of the insertion end and along the side walls of the carrier member during positioning of the carrier member in the subject's body. A multi-core optical fiber configured for use in a medical device for positioning in a subject's body is also provided. A system and method for guiding positioning of a medical device in a subject's body is also provided.
G01D 5/353 - Mechanical means for transferring the output of a sensing memberMeans for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for convertingTransducers not specially adapted for a specific variable using optical means, i.e. using infrared, visible or ultraviolet light with attenuation or whole or partial obturation of beams of light the beams of light being detected by photocells influencing the transmission properties of an optical fibre
G01K 11/3206 - Measuring temperature based on physical or chemical changes not covered by group , , , or using changes in transmittance, scattering or luminescence in optical fibres at discrete locations in the fibre, e.g. using Bragg scattering
A spectacle lens can inhibit ametropia of the eyes and ensure full visibility. The spectacle lens comprises: first refraction areas and second refraction areas. Each first refraction area has a first refraction force that may be based on a prescription for correcting the ametropia of the eyes. Each second refraction area has a refraction force different from the first refraction force and may function to focus images on the positions except the retina of the eyes, to inhibit the development of the ametropia. Near the central part of the lens, the second refraction areas form a plurality of independent island-shaped areas, and the first refraction areas form the areas beyond the areas of the second refraction areas.
A microfluidic device containing an inlet, a microchannel in fluid communication with the inlet, and a plurality of outlets in fluid communication with the microchannel. The microchannel contains a loop; or from about 1 loop to about 50 loops; or from about 2 loops to about 25 loops; or from about 5 loops to about 15 loops. A method for detecting an infected cell may employ the microfluidic device.
(1) Knit fabrics; laminated fabrics with acrylic resins for use in the manufacture of clothing; laminated fabrics with knitted fabrics for use in the manufacture of clothing; laminated fabrics with nylon resins for use in the manufacture of clothing; laminated fabrics with polyester resins for use in the manufacture of clothing; laminated fabrics with polyurethane resins for use in the manufacture of clothing; laminated fabrics with water proofing fabrics for use in the manufacture of clothing; non-woven fabrics; textile fabrics; textile fabrics for the manufacture of clothing; textile handkerchiefs; textile labels; textile linings for garments; textiles for footwear; textiles for headwear; towels of textile; woven fabrics;
(2) Athletic clothing; athletic footwear; boots; caps; casual clothing; casual footwear; dresses; gloves; hats; jackets; jumpsuits; pants; sandals; shirts; shoes; shorts; skirts; sweaters; t-shirts; tank tops
22.
Water-responsive shape memory wool fiber, fabric and textile comprising thereof, and method for preparing the same
A woven, water-vapor permeable, water-responsive, shape-memory wool fabric that possesses switchable pore size and shape responsive to varying water content absorbed thereby is demonstrated, more particularly, the wool fabric exerts corresponding thermal and water vapor regulations between the wearer and the surroundings with respect to the temperature and humidity changes.
D02G 1/02 - Producing crimped or curled fibres, filaments, yarns or threads, giving them latent characteristics by twisting, fixing the twist and backtwisting, i.e . by imparting false twist
D02G 3/26 - Yarns or threads characterised by constructional features with characteristics dependent on the amount or direction of twist
The present disclosure relates to a surface comprising a photocatalyst affixed thereupon via an adhesive layer and methods for affixing the photocatalyst to the surface via the adhesive layer. The present disclosure also provides a purifier comprising the photocatalyst affixed surface and a purifier system comprising such purifier.
A spectacle lens can inhibit ametropia of the eyes and ensure full visibility. The spectacle lens comprises: first refraction areas and second refraction areas. Each first refraction area has a first refraction force that may be based on a prescription for correcting the ametropia of the eyes. Each second refraction area has a refraction force different from the first refraction force and may function to focus images on the positions except the retina of the eyes, to inhibit the development of the ametropia. Near the central part of the lens, the second refraction areas form a plurality of independent island-shaped areas, and the first refraction areas form the areas beyond the areas of the second refraction areas.
A human body modelling method and apparatus and an electronic device. The method comprises: acquiring at least one human body image; extracting an original profile of a human body from the human body image; calculating a body surface profile of the human body according to the original profile; and constructing a three dimensional human body model according to the body surface profile. The establishment of a three dimensional human body model originates from two dimensional human body images, without using a human body scanner to scan a human body, which reduces the cost of establishing the three dimensional human body model. Moreover, there is no requirement for the position and dressing of a human body object, and the process of establishing the three dimensional human body model is more convenient.
A multi-level-architecture multi-fiber composite yarn includes a composite yarn having a first anisotropic expansion coefficient in an axial and/or radial direction, and a matrix material included with the yarn, wherein the matrix material has a second anisotropic expansion coefficient that is different from the first anisotropic expansion coefficient in at least one of the axial or radial directions. A method of fabricating a multi-level-architecture multi-fiber composite yarn includes infiltrating a composite yarn having a first anisotropic expansion coefficient in an axial and/or radial directions with a matrix material having a second anisotropic expansion coefficient different from the first anisotropic expansion coefficient in the axial or radial direction.
A photocatalyst includes a composite fiber having at least two crystalline semi-conductors that provide a heterojunction structure in the composite fiber.
B01J 35/00 - Catalysts, in general, characterised by their form or physical properties
B01J 23/80 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups with zinc, cadmium or mercury
B01J 19/12 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor employing electromagnetic waves
In an aspect of the disclosure there is provided a vibration reducing apparatus for a percussive tool having an axis of reciprocation. The apparatus comprises, a guide frame and at least one member extending across the axis of reciprocation. An assembly extending in a direction of along the axis of reciprocation comprises at least two layers and each layer comprises four interconnected elongate members pivotally attached and rotatable with respect to each other to define a polygon; and the assembly has at least one biasing means. A handle is movably coupled to the guide frame and supported on the assembly. The apparatus provides decreasing stiffness with increasing compression of the assembly under an applied load to the handle for reducing vibration in a predetermined frequency range.
A spectacle lens can inhibit ametropia of the eyes and ensure full visibility. The spectacle lens comprises: first refraction areas and second refraction areas. Each first refraction area has a first refraction force that may be based on a prescription for correcting the ametropia of the eyes. Each second refraction area has a refraction force different from the first refraction force and may function to focus images on the positions except the retina of the eyes, to inhibit the development of the ametropia. Near the central part of the lens, the second refraction areas form a plurality of independent island-shaped areas, and the first refraction areas form the areas beyond the areas of the second refraction areas.
An apparatus for imparting false twist to a staple yarn comprising a yarn guide for guiding a staple yarn along a path and a false twist device comprising a convex surface for engagement with a staple yarn so as to impart a force to the staple yarn when the staple yarn engages with and traverses the convex surface of the false twist device, and wherein the relative positioning between the yarn guide and the convex surface of the false twist device is adjustable such that, when a staple yarn is engaged with the convex surface of the false twist device and extends between the yarn guide and the false twist device, the amount of contact between the staple yarn and the convex surface of the false twist device can be controlled.
D02G 1/02 - Producing crimped or curled fibres, filaments, yarns or threads, giving them latent characteristics by twisting, fixing the twist and backtwisting, i.e . by imparting false twist
The present disclosure provides a method and system for analysing one or more edible oil samples. In an embodiment the disclosure provides for calibrating the matrix-assisted laser desorption/ionisation mass spectrometry (MALDI-MS) data obtained for one or more edible oil samples to obtain calibrated spectral data; and comparing the calibrated spectral data derived from the one or more samples against a library of calibrated MALDI-MS spectra for a plurality of edible oil samples to determine the most likely composition of the one or more edible oil samples.
H01J 49/16 - Ion sourcesIon guns using surface ionisation, e.g. field-, thermionic- or photo-emission
H01J 49/00 - Particle spectrometers or separator tubes
G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
H01J 49/04 - Arrangements for introducing or extracting samples to be analysed, e.g. vacuum locksArrangements for external adjustment of electron- or ion-optical components
An optical system including a layer having a reflective surface, the layer is adapted to provide a primary image and a secondary image. The secondary image is provided by a reflection of an object facing the reflective surface, and the primary and the secondary images are viewable by a viewer having a retina. The secondary image is focused in front of the retina to generate myopic defocus.
A method for retarding or reversing progression of myopia of a viewer contains the steps of using an immersive or non-immersive device to create a plurality of image planes in the eye of the viewer. While an image plane is located on the retina, at least one image plane is not on the retina, thereby generating myopic defocus. Immersive and non-immersive devices and systems for such a method are also described.
The present invention relates to the use of dopants for polymer optical fibers or polymer waveguides containing the dopants, sensors in the polymer optical fibers or polymer waveguides, which may be used in the biomedical industry for the measurement of different physiological and physical variables.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
G02B 6/122 - Basic optical elements, e.g. light-guiding paths
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
G02B 6/12 - Light guidesStructural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
36.
Coated nanofiller/polymer composite sensor network for guided-wave-based structural health monitoring
A method for forming a structural-strain sensor network on a structure is provided. The sensor network has plural nanocomposite sensing elements having high sensitivity, and can be quickly fabricated. The method comprises attaching a molding layer having openings onto the surface, and filling the openings with a coating material made of nanocomposite hybrid material. After immobilizing the coating material in the openings, the sensing elements are formed and the molding layer is removed. Electrical wires are formed on the surface such that two opposite electrodes are formed on each sensing element. The resistance between the two electrodes indicates a strain experienced. The sensor network finds applications in identifying a damaged location or an impact location on the structure for structural health monitoring. Voltage waveforms measured at the sensing elements are analyzed to estimate the damaged location or the impact location according to a guided-wave propagation model.
G01M 5/00 - Investigating the elasticity of structures, e.g. deflection of bridges or aircraft wings
G01L 1/22 - Measuring force or stress, in general by measuring variations in ohmic resistance of solid materials or of electrically-conductive fluidsMeasuring force or stress, in general by making use of electrokinetic cells, i.e. liquid-containing cells wherein an electrical potential is produced or varied upon the application of stress using resistance strain gauges
B05D 1/32 - Processes for applying liquids or other fluent materials using means for protecting parts of a surface not to be coated, e.g. using stencils, resists
B29C 67/00 - Shaping techniques not covered by groups , or
A resistance-voltage (R-V) transformation system used in dynamic strain measurement for a structure is provided. The system has single-channel (SC) circuit units each for producing a voltage corresponding to a resistance of a sensing element of a structural-strain sensing network. Each SC circuit unit has a R-V transformation module for converting the resistance into the voltage, a band-pass filter module for filtering the R-V transformation module output after a direct-current bias therein is removed, and a high-gain amplification module for amplifying the filter output. The band-pass filter module is configured such that an unwanted low-frequency component induced by resistance drift of the sensing element is removed while allowing a guided-wave signal component to pass through. Particularly advantageous for the sensing network using nanocomposite sensing elements, the R-V transformation system is useful for a wide range of sensor resistance values, mitigating adverse effects of resistance drift, and enabling simplicity in wiring.
G01L 1/18 - Measuring force or stress, in general using properties of piezo-resistive materials, i.e. materials of which the ohmic resistance varies according to changes in magnitude or direction of force applied to the material
G01M 5/00 - Investigating the elasticity of structures, e.g. deflection of bridges or aircraft wings
A voltage balancing circuit is applied to a power supply system. The power supply system comprises N power storage devices. The voltage balancing circuit comprises: N switches, N capacitors and a controller; the N switches are respectively connected to the N serial power storage devices; the N switches are respectively connected to the first terminals of the N capacitors; the second terminals of the N capacitors are connected to a common neutral line; the controller is connected to the N switches through a control line to control the switching of the N switches. The voltage balancing circuit avoids power loss when balancing the voltage of a plurality of serial power storage devices, and is small in size and low-cost, and balances voltage quickly.
H02J 7/00 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries
H03K 17/687 - Electronic switching or gating, i.e. not by contact-making and -breaking characterised by the use of specified components by the use, as active elements, of semiconductor devices the devices being field-effect transistors
H02J 7/34 - Parallel operation in networks using both storage and other DC sources, e.g. providing buffering
40.
Prodrug of green tea epigallocatechin-3-gallate (pro-EGCG) for use in the treatment of endometriosis
Method of treating endometriosis and related indications, comprising the administration of Pro-EGCG, a synthetic and derivative product of epigallocatechin-3-gallate [(−)-EGCG]. Use of Pro-EGCG in the manufacture of a medicament for treating endometriosis and related indications. Pro-EGCG for use in the treatment of endometriosis and related indications.
The present invention relates to novel series of amine-containing flavonoids and compositions containing the compounds, as well as the synthesis and the use of the same. The invention also relates to methods of treatment and prevention of diseases, in particular, parasitic infections including Leishmaniasis, comprising administration of the compounds.
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
A61K 31/443 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
A61K 31/4545 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
A61K 31/551 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep
A61K 31/4439 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A61K 31/444 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. amrinone
A61K 31/4709 - Non-condensed quinolines containing further heterocyclic rings
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61K 31/506 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
C07D 405/14 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
C07D 405/12 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
C07D 311/30 - Benzo [b] pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
A61K 31/4433 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
A spectacle lens can inhibit ametropia of the eyes and ensure full visibility. The spectacle lens comprises: first refraction areas and second refraction areas. Each first refraction area has a first refraction force that may be based on a prescription for correcting the ametropia of the eyes. Each second refraction area has a refraction force different from the first refraction force and may function to focus images on the positions except the retina of the eyes, to inhibit the development of the ametropia. Near the central part of the lens, the second refraction areas form a plurality of independent island-shaped areas, and the first refraction areas form the areas beyond the areas of the second refraction areas.
This invention is in the preparation of bulk nanostructured pure titanium at cryogenic temperatures using equal channel angular pressing and rolling, allowing the whole microstructures of pure titanium to be refined into the one that the mean grain size is smaller than 100 nm.
The Royal Institution for the Advancement of Learning/McGill University (Canada)
Inventor
Chow, Larry Ming Cheung
Chan, Tak Hang
Chan, Kin Fai
Wong, Iris Lai King
Law, Man Chun
Abstract
50 at or below 10 nM in BCRP-overexpressed cell lines, indicating that these bivalent triazoles more selectively inhibit BCRP transporter than the P-gp and MRP1 transporters. Most of the dimers are notably safe MDR chemosensitizers as indicated by their high therapeutic index values.
C07D 311/30 - Benzo [b] pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
C07D 311/32 - 2, 3-Dihydro derivatives, e.g. flavanones
C07D 405/14 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
C07D 405/12 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
A61K 47/55 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
The present invention discloses a current-source-output light-emitting-diode (LED) driver based on LCLC circuit to provide a constant output current regardless of variations in LED parameters. In the LCLC circuit, the number of additional capacitors is scalable with the number of LED strings for current balancing. Moreover, the input impedance of the improved LCLC circuit is designed to be resistive at the operating frequency to minimize reactive power. The conventional duty cycle control can easily incorporate zero-voltage-switching (ZVS).
An interactive exoskeleton robotic knee system for assist walking and gait training. The system comprises of an exoskeleton framework to be attached to the thigh and shank of the user's leg; electric motor; mechanical lock; motion sensor assembled on the lower limb unit, and a control box. The system provides extension and flexion movement in the knee joint.
A portable electrical motor-driven exoskeleton ankle joint robot with gear transmission and control system which is intended to provide walking assistance in different speed and walking conditions to persons with disability in walking or muscle weakness or joint problem.
A method for retarding or reversing progression of myopia of a viewer includes providing an object in front of the viewer; providing a transparent layer between the viewer and the object; and providing a primary image on the transparent layer, the transparent layer allows the viewer to see the object as a secondary image simultaneously with the primary image, wherein the secondary image is focused in front of the central region of the retina. A method for reducing hyperopia of a viewer includes providing an object in front of the viewer to provide a primary image; providing a transparent layer between the viewer and the object; providing a secondary image on the transparent layer, the transparent layer allows the viewer to see the primary image simultaneously with the secondary image, wherein the secondary image is focused behind the central region of the retina. Other systems are also described herein.
This invention provides a cyclically-coupled (CC-) quasi-cyclic (QC-) low-density parity-check (LDPC) code and its decoder architecture. The essence of the invention is to introduce the convolutional nature to a plurality of individual block codes internally so as to form a resultant block code with a prolonged code length while slightly increasing the hardware complexity in decoder realization. The CC-QC-LDPC code is formed by cyclically coupling a plurality of sub-codes each being a QC-LDPC code such that overlapping of some variable nodes between two consecutive sub-codes results. The decoder comprises plural sub-decoders each configured to decode the channel messages for one sub-code. The sub-decoders are arranged in a ring shape such that an individual sub-decoder is configured to communicate edge messages with two neighboring sub-decoders adjacent to said individual sub-decoder in the decoding of the channel messages. The sub-decoders are configured to operate concurrently for simultaneously decoding individual sub-codes.
H03M 13/11 - Error detection or forward error correction by redundancy in data representation, i.e. code words containing more digits than the source words using block codes, i.e. a predetermined number of check bits joined to a predetermined number of information bits using multiple parity bits
H03M 13/00 - Coding, decoding or code conversion, for error detection or error correctionCoding theory basic assumptionsCoding boundsError probability evaluation methodsChannel modelsSimulation or testing of codes
H04L 1/00 - Arrangements for detecting or preventing errors in the information received
2. The system comprises an FPGA controller (20), and a video signal decoder (10), a first external memory (41), a second external memory (42) and an LED display module (30) which are respectively connected to the FPGA controller (20). The FPGA controller (20) comprises N LED drive modules (231-23N) which are connected in parallel. The drive method and system can enhance the luminous efficacy of an LED, and can also conduct linear dimming on the LED.
G09G 1/00 - Control arrangements or circuits, of interest only in connection with cathode-ray tube indicators
G09G 5/399 - Control of the bit-mapped memory using two or more bit-mapped memories, the operations of which are switched in time, e.g. ping-pong buffers
G09G 3/32 - Control arrangements or circuits, of interest only in connection with visual indicators other than cathode-ray tubes for presentation of an assembly of a number of characters, e.g. a page, by composing the assembly by combination of individual elements arranged in a matrix using controlled light sources using electroluminescent panels semiconductive, e.g. using light-emitting diodes [LED]
G09G 3/20 - Control arrangements or circuits, of interest only in connection with visual indicators other than cathode-ray tubes for presentation of an assembly of a number of characters, e.g. a page, by composing the assembly by combination of individual elements arranged in a matrix
H05B 33/08 - Circuit arrangements for operating electroluminescent light sources
G09G 3/3275 - Details of drivers for data electrodes
G09G 3/3283 - Details of drivers for data electrodes in which the data driver supplies a variable data current for setting the current through, or the voltage across, the light-emitting elements
51.
Method and device for contactless biometrics identification
The present invention provides a new method and a device for the contactless human identification using biometrics images. The present invention develops a robust feature extraction algorithm to recover three-dimensional (3D) shape information from biometrics images. Further, it provides significantly improved performance than what is possible from the state-of-art methods, adding practicality for real applications on mobile platform, smartphones, and also as add-on system for conventional fingerprint system. The present invention's unique advantages are based on its computational simplicity, efficient matching and requiring least storage. Experiments were conducted to confirm very high accuracy and reliability on a number of biometric modalities including iris, palmprint, and finger knuckle images.
An optical transmission system comprises at least one first connection point and one second connection point arranged to transmit and receive at least one channel signal transmitted via at least one optical means connecting the first connection point and the second connection, wherein each of the at least one channel signal is reversibly configurable to be transmitted in either a first direction or a second direction between the first connection point and the second connection point. A method of transmitting at least one channel signal between a first connection point and a second connection point via at least one optical media in an optical transmission system, wherein each of the at least one channel signal is reversibly configurable to be transmitted in either a first direction or a second direction between the first and the second connection points.
A photocatalyst includes a composite fiber having at least two crystalline semi-conductors that provide a heterojunction structure in the composite fiber.
B01J 21/06 - Silicon, titanium, zirconium or hafniumOxides or hydroxides thereof
B01J 19/12 - Processes employing the direct application of electric or wave energy, or particle radiationApparatus therefor employing electromagnetic waves
B01J 23/80 - Catalysts comprising metals or metal oxides or hydroxides, not provided for in group of the iron group metals or copper combined with metals, oxides or hydroxides provided for in groups with zinc, cadmium or mercury
B01J 27/057 - Selenium or telluriumCompounds thereof
54.
Synthesis and use of amine-containing flavonoids as potent anti-leishmanial agents
The present invention relates to novel series of amine-containing flavonoids and compositions containing the compounds, as well as the synthesis and the use of the same. The invention also relates to methods of treatment and prevention of diseases, in particular, parasitic infections including Leishmaniasis, comprising administration of the compounds.
C07D 311/30 - Benzo [b] pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
C07D 405/12 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
C07D 405/14 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 31/4433 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
A61K 31/4439 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
A61K 31/444 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. amrinone
A61K 31/4545 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
A61K 31/551 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogens as ring hetero atoms, e.g. clozapine, dilazep
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
55.
Prodrug of green tea epigallocatechin-3-gallate (Pro-EGCG) for use in the treatment of endometriosis
Method of treating endometriosis and related indications, comprising the administration of Pro-EGCG, a synthetic and derivative product of epigallocatechin-3-gallate [(−)-EGCG]. Use of Pro-EGCG in the manufacture of a medicament for treating endometriosis and related indications. Pro-EGCG for use in the treatment of endometriosis and related indications.
A61K 31/35 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
A61K 31/353 - 3,4-Dihydrobenzopyrans, e.g. chroman, catechin
A61K 9/00 - Medicinal preparations characterised by special physical form
A system using a three-coil topology for wireless power transfer is disclosed. The system comprises a primary resonator coupled to a power source, a repeater resonator and a receiver resonator. The primary resonator has a primary coil, and the repeater resonator has a repeater coil adjacent to the primary coil. The repeater coil and the primary coil are separated by a distance selected, and the repeater coil is configured, to amplify a primary-coil current by inductively generating a repeater-coil current that is substantially greater than the primary-coil current. A magnetic field contributed from both the primary-coil current and the repeater-coil current is generated while the power source needs not provide a terminal voltage across the repeater coil, thereby discouraging occurrence of voltage stress at the power source. The receiver resonator has a receiver coil, which receives the magnetic field to inductively generate a receiver-coil current for feeding to a load.
H02J 5/00 - Circuit arrangements for transfer of electric power between ac networks and dc networks
H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
57.
Method and system for retarding the progression of myopia
A method for retarding the progression of myopia in a human eye, the method comprising: providing (41) a concentric annular multi-zone refractive lens including: at least one correcting zone of optical power for correcting (42) refractive error, and at least one defocusing zone for projecting (43) at least one non-homogenous defocused image in front of at least a part of retina to inhibit myopic eye growth, the at least one defocusing zone having at least one less negative power; wherein the correcting and defocusing zones are alternated (45) in the lens and the zones are connected (46) to each other through integrated progressive transition curves.
The presently claimed invention provides a barium strontium titanate/strontium titanate/gallium arsenide (BST/STO/GaAs) heterostructure comprising a gallium arsenide (GaAs) substrate, at least one strontium titanate (STO) layer, and at least one barium strontium titanate (BST) layer. The BST/STO/GaAs heterostructure of the present invention has a good temperature stability, high dielectric constant and low dielectric loss, which enable to fabricate tunable ferroelectric devices. A method for fabricating the BST/STO/GaAs heterostructure is also disclosed in the present invention, which comprises formation of at least one STO layer on the GaAs substrate by a first laser molecular beam epitaxial system, and formation of at least one BST layer on the STO layer by a second laser molecular beam epitaxial system.
H01L 21/00 - Processes or apparatus specially adapted for the manufacture or treatment of semiconductor or solid-state devices, or of parts thereof
H01L 21/02 - Manufacture or treatment of semiconductor devices or of parts thereof
H01L 29/205 - Semiconductor bodies characterised by the materials of which they are formed including, apart from doping materials or other impurities, only AIIIBV compounds including two or more compounds in different semiconductor regions
59.
Alkyne-, azide- and triazole-containing flavonoids as modulators for multidrug resistance in cancers
A triazole bridged flavonoid dimer compound library was efficiently constructed via the cycloaddition reaction of a series of flavonoid-containing azides (Az 1-15) and alkynes (Ac 1-17). These triazole bridged flavonoid dimers and their precursor alkyne- and azide-containing flavonoids were screened for their ability to modulate multidrug resistance (MDR) in P-gp-overexpressed cell line (LCC6MDR), MRP1-overexpressed cell line (2008/MRP1) and BCRP-overexpressed cell line (HEK293/R2 and MCF7-MX100). Generally, they displayed very promising MDR reversal activity against P-gp-, MRP1- and BCRP-mediated drug resistance. Moreover, they showed different levels of selectivity for various transporters. Overall, they can be divided into mono-selective, dual-selective and multi-selective modulators for the P-gp, MRP1 and BCRP transporters. The EC50 values for reversing paclitaxel resistance (141-340 nM) of LCC6MDR cells, DOX (78-590 nM) and vincristine (82-550 nM) resistance of 2008/MRP1 cells and topotecan resistance (0.9-135 nM) of HEK293/R2 and MCF7-MX100 cells were at nanomolar range. Importantly, a number of compounds displayed EC50 at or below 10 nM in BCRP-overexpressed cell lines, indicating that these bivalent triazoles more selectively inhibit BCRP transporter than the P-gp and MRP1 transporters. Most of the dimers are notably safe MDR chemosensitizers as indicated by their high therapeutic index values.
C07D 405/14 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
C07D 405/12 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
A61K 47/48 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
60.
Brain biofeedback device with radially adjustable electrodes
A head-mountable EEG electrode-containing device is provided based on radially adjustable electrodes to fit the wearer's unique head size and shape. The head-mountable device with an electrode array positioned therein includes multiple head-mountable device sections that are interconnected by mechanical fasteners to facilitate sizing and positioning of the head-mountable device. An array of resilient sleeves is positioned within each head-mountable device section. Each resilient sleeve houses an individual electrode and is deformable for self-orienting. The deformation of the sleeve is such that a central axis passing through the individual electrode housed within the resilient sleeve is maintained in a position approximately normal to a plane tangential to a scalp portion positioned beneath that electrode.
The presently claimed invention provides a highly conductive composite used for electric charge transport, and a method for fabricating said composite. The composite comprises a plurality of one-dimensional semiconductor nanocomposites and highly conductive nanostructures, and the highly conductive nanostructures are incorporated into each of the one-dimensional semiconductor nanocomposite. The composite is able to provide fast electric charge transport, and reduce the rate of electron-hole recombination, ultimately increasing the power conversion efficiency for use in solar cell; provide fast electrons transport, storage of electrons and large surface area for adsorption and reaction sites of active molecular species taking part in photocatalytic reaction; enhance the sensitivity of a surface for biological and chemical sensing purposes for use in biological and chemical sensors; and lower the impedance and increase the charge storage capacity of a lithium-ion battery.
H01L 29/06 - Semiconductor bodies characterised by the shapes, relative sizes, or dispositions of the semiconductor regions
H01L 31/0352 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by their semiconductor bodies characterised by their shape or by the shapes, relative sizes or disposition of the semiconductor regions
B82Y 99/00 - Subject matter not provided for in other groups of this subclass
H01L 21/02 - Manufacture or treatment of semiconductor devices or of parts thereof
H01L 51/00 - Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof
B82Y 10/00 - Nanotechnology for information processing, storage or transmission, e.g. quantum computing or single electron logic
H01L 29/12 - Semiconductor bodies characterised by the materials of which they are formed
H01L 29/16 - Semiconductor bodies characterised by the materials of which they are formed including, apart from doping materials or other impurities, only elements of Group IV of the Periodic System in uncombined form
H01L 51/05 - Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof specially adapted for rectifying, amplifying, oscillating or switching and having at least one potential-jump barrier or surface barrier; Capacitors or resistors with at least one potential-jump barrier or surface barrier
H01M 4/131 - Electrodes based on mixed oxides or hydroxides, or on mixtures of oxides or hydroxides, e.g. LiCoOx
H01M 4/485 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of mixed oxides or hydroxides for inserting or intercalating light metals, e.g. LiTi2O4 or LiTi2OxFy
A method for using dual indices to support query expansion, relevance/non-relevance models, blind/relevance feedback and an intelligent search interface, the method comprising: accessing an inverted index to obtain an initial retrieval of results in response to a query, and to generate a rank list of the results, the results referring to information units (IUs) where the query occurs; and determining a number of “N” IUs in the results that are assumed to be relevant by accessing a forward index; wherein the forward index and inverted index have pointers to locations in the IUs where terms of the query occur, and the forward index retrieves a term frequency vector of the IU or a set of contexts of the IU.
A semi-crystalline shape memory polymer with transition temperature near body temperature and the production method thereof is disclosed. The shape memory polymer comprises a polymer chain which further comprises a plurality of prepolymers and a plurality of chain extenders bonding the prepolymers together in which each prepolymer further comprises a plurality of synthesized units. The above mentioned synthesized unit is obtained by reacting polymer diol with first diisocyanate. The obtained synthesized units are polymerized together with second diisocyanate and chain extender to form the shape memory polymer.
C12N 9/78 - Hydrolases (3.) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
A61K 47/48 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers, inert additives the non-active ingredient being chemically bound to the active ingredient, e.g. polymer drug conjugates
A multispectral imaging color measurement system, comprising a dark room, a sample platform and an imaging device for capturing said object being measured; a controllable illumination device, a filter wheel unit, an imaging signal processing unit and an electronic control unit. A method for processing imaging signals of the multispectral imaging color measurement is also proposed. The multispectral imaging color measurement system and the method for processing imaging signals thereof can overcome the inaccuracy of traditional digital imaging systems and the limits of spectrophotometer systems and provide users in the textile industry with highly accurate color measurement and evaluation.
A wearable power assistive device for hand rehabilitation includes a hand brace having an external platform and an internal platform connected to and spaced inwardly from the external platform. Five finger assemblies are adjustably mounted on and extending from the distal end of the external platform. Each finger assembly includes a proximal follower assembly for a metacarpophalangeal joint. Five motors are used to actuate the five finger assemblies respectively. Each motor is mounted in close proximity to the external platform and has one end connected to the external platform and another end coupled to its proximal follower assembly by a ball joint in order to facilitate transfer of force and minimize mechanical stress on the other parts of the device.
A Low-Density Parity-Check Convolutional Code (LPDCCC) decoder (10) for partial parallel decoding of low-density parity-check convolutional codes, the decoder having: a plurality of pipeline processors (11) to receive channel messages and edge-messages; each processor (11) having: a plurality of block processing units (BPUs) (13), each BPU (13) having a plurality of check node processors (CNPs) (14) to process check nodes that enter into the processor (11) and a plurality of variable node processors (VNPs) (15) to process variable nodes that are about to leave the processor (11); and a plurality of Random Access Memory (RAM) blocks (30) for dynamic message storage of the channel messages and the edge-messages; wherein in each processor (11), the VNPs (15) are directly connected to corresponding RAM blocks (30), and the CNPs (14) are directly connected to corresponding RAM blocks (30) such that the connections from the VNPs (15) and CNPs (14) to the corresponding RAM blocks (30) are pre-defined and fixed according to a parity-check matrix of an unterminated time-varying periodic LDPCCC.
H03M 13/00 - Coding, decoding or code conversion, for error detection or error correctionCoding theory basic assumptionsCoding boundsError probability evaluation methodsChannel modelsSimulation or testing of codes
68.
Method of mass production of tetrakis(p-nitrophenyl)porphyrins
A method of mass production of tetrakis(p-nitrophenyl)porphyrins, by which successful isolation of the barely soluble product from meso-aryl nitration of tetraphenylporphyrin toward a remarkable yield of nearly 90% has been realized by means of a solid phase extraction technique. This is a simpler and more straight forward synthetic method, suitable production at an industrial scale with lower cost, shorter synthetic time and lower solvent consumption. A preferred species of tetrakis(p-nitrophenyl)porphyrin produced by a subject method is:
C07D 487/22 - Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups in which the condensed system contains four or more hetero rings
69.
Bilayer dye sensitized solar cell and fabrication method thereof
A photovoltaic cell comprises a first electrode that includes a first transparent conductive substrate, a first layer having a plurality of first semiconductor nanofibers, and a second layer having a plurality of second semiconductor super-fine fibers, the first semiconductor nanofibers having an average diameter smaller than an average diameter of the second semiconductor super-fine fibers, a light absorbing material adsorbed to at least some of the first semiconductor nanofibers and second semiconductor super-fine fibers, a second electrode includes a second transparent conductive substrate, and electrolytes dispersed in the first and second layers.
H01L 31/0352 - SEMICONDUCTOR DEVICES NOT COVERED BY CLASS - Details thereof characterised by their semiconductor bodies characterised by their shape or by the shapes, relative sizes or disposition of the semiconductor regions
B82Y 20/00 - Nanooptics, e.g. quantum optics or photonic crystals
B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
70.
Item of clothing for daily pharmacological treatment of a fungal infection
An item of clothing (10) for daily pharmacological treatment of a fungal infection, comprising: a textile material (20) to manage moisture when the item of clothing (10) is worn; microcapsules (30) grafted on the textile material (20); and antifungal agents encapsulated within the microcapsules (30) to pharmacologically treat the fungal infection when released from the microcapsules (30).
regium polysaccharide functionalized nano-selenium hydrosol when the red color of the product is no longer deepened. The polysaccharides are used to control the particle size of nano-selenium, to obtain functionalized nano-elemental selenium with high anti-tumor activity and low toxicity. The anti-tumor activity of the biologically active molecule polysaccharides and the physiological effect of nano-selenium are combined, and a synergistic anti-tumor effect is achieved.
A61K 33/04 - Sulfur, selenium or telluriumCompounds thereof
A61K 31/715 - Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkagesDerivatives thereof, e.g. ethers, esters
A method for stabilizing conjugates between macromolecule and nanoparticle by forming a thin reinforcement layer over the surface of a nanoparticle after macromolecule chains have attached to the surface of the nanoparticle. The stabilized conjugates can be used in a wide range of applications such as in vitro diagnostics, in vivo imaging and therapeutics, which need to be conducted under various severe or harsh conditions.
A sensor for measuring flow speed of a fluid, comprising: a light-absorbing optical fiber having a fiber Bragg grating inscribed in the fiber; wherein light is emitted into the light-absorbing optical fiber to heat the optical fiber and the fiber Bragg grating, and when the fluid passes over the sensor, the flow speed of the fluid is determined by the rate of heat loss from the sensor, and the temperature of the sensor is determined from the wavelength shift of the central wavelength of the fiber Bragg grating.
G02B 6/00 - Light guidesStructural details of arrangements comprising light guides and other optical elements, e.g. couplings
G01P 5/10 - Measuring speed of fluids, e.g. of air streamMeasuring speed of bodies relative to fluids, e.g. of ship, of aircraft by measuring thermal variables
G01F 1/688 - Structural arrangementsMounting of elements, e.g. in relation to fluid flow using a particular type of heating, cooling or sensing element
G02B 6/12 - Light guidesStructural details of arrangements comprising light guides and other optical elements, e.g. couplings of the optical waveguide type of the integrated circuit kind
74.
Detection system for assisting a driver when driving a vehicle using a plurality of image capturing devices
A detection system (5) for assisting a driver when driving a vehicle, the system (5) comprising: a plurality of image capturing devices (98) mounted to the vehicle to capture images of the external environment of the vehicle; an image processing module (95) to identify potential hazards in real-time from the captured images and to superimpose information of the external environment relating to the identified potential hazards; and at least one display device (92) to display images processed by the image processing module in real-time; wherein the superimposed information is provided in an area of the display device (92) to ensure visual clarity of the images of the external environment.
A non-invasive glucose sensor (10) for detecting an amount of glucose in bodily fluid, comprising: an organic electrochemical transistor (OECT) having a gate electrode (20); wherein a surface of the gate electrode (20) is modified with an enzyme and a nanomaterial to increase sensitivity and selectivity of the gate electrode (20).
A fundus camera using infrared light sources, which included an imaging optical path and an optical path for focusing and positioning and two optical paths share a common set of retina objective lens, and a computer-assisted method for retinal vessel segmentation in general and diabetic retinopathy (DR) image segmentation in particular. The method is primarily based on Multiscale Production of the Matched Filter (MPMF) scheme, which together the fundus camera, is useful for non-invasive diabetic retinopathy detection and monitoring.
G06K 9/00 - Methods or arrangements for reading or recognising printed or written characters or for recognising patterns, e.g. fingerprints
A61B 3/12 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for looking at the eye fundus, e.g. ophthalmoscopes
G06K 9/46 - Extraction of features or characteristics of the image
A fiber-inline MZI device for temperature sensing or refractive index (RI) sensing, the device comprising: a section of a Photonic Crystal Fiber (PCF) having at least two air holes infiltrated with a liquid analyte to form a waveguide channel, the liquid analyte forming rods in the PCF; wherein the rods leave an interference fringe pattern in the transmission spectrum when light is injected into the PCF, and fringe dips are tracked over a wide wavelength range in order to sense the temperature or refractive index.
Quinoline derivatives showing anticancer activities against cancer cell lines of hepatocellular carcinoma (Hep3B), lung carcinoma (A549), esophageal squamous cell carcinoma (HKESC-1, HKESC-4 and KYSE150). The quinoline derivatives have a backbone structure of the following formulas:
A system for bonding electrical devices using an electrically conductive adhesive to adhere the electrical devices together, the system including: an ultrasonic transducer to generate an ultrasonic vibration; and an ultrasonic to thermal energy apparatus operatively attached to and covering an operational end of the ultrasonic transducer, the ultrasonic to thermal energy apparatus damping the ultrasonic vibration to minimize ultrasonic vibration transmitted to a first electrical device and causing the conversion of the ultrasonic vibration to a heating pulse which is conducted through the first electrical device to the adhesive. Whereby the adhesive is softened by the heating pulse to bond the electrical devices together.
B32B 37/06 - Methods or apparatus for laminating, e.g. by curing or by ultrasonic bonding characterised by the heating method
H01L 23/00 - Details of semiconductor or other solid state devices
H01L 25/065 - Assemblies consisting of a plurality of individual semiconductor or other solid-state devices all the devices being of a type provided for in a single subclass of subclasses , , , , or , e.g. assemblies of rectifier diodes the devices not having separate containers the devices being of a type provided for in group
H01L 25/00 - Assemblies consisting of a plurality of individual semiconductor or other solid-state devices
80.
Method and system for retarding the progression of myopia
A method for retarding the progression of myopia in a human eye, the method comprising: providing (41) a concentric annular multi-zone refractive lens including: at least one correcting zone of optical power for correcting (42) refractive error, and at least one defocusing zone for projecting (43) at least one non-homogenous defocused image in front of at least a part of retina to inhibit myopic eye growth, the at least one defocusing zone having at least one less negative power; wherein the correcting and defocusing zones are alternated (45) in the lens and the zones are connected (46) to each other through integrated progressive transition curves.
A method for making items of clothing having shape memory, the method comprising: synthesizing (31) a shape memory polyurethane; subjecting (34) the shape memory polyurethane to wet spinning, dry spinning, melt spinning or multi-component spinning in order to produce shape memory fibers; and knitting or weaving (36) the shape memory fibers to form the item of clothing.
D04B 1/24 - Weft knitting processes for the production of fabrics or articles not dependent on the use of particular machinesFabrics or articles defined by such processes specially adapted for knitting goods of particular configuration wearing apparel
D04B 1/26 - Weft knitting processes for the production of fabrics or articles not dependent on the use of particular machinesFabrics or articles defined by such processes specially adapted for knitting goods of particular configuration wearing apparel stockings
C08G 18/10 - Prepolymer processes involving reaction of isocyanates or isothiocyanates with compounds having active hydrogen in a first reaction step
C08G 18/42 - Polycondensates having carboxylic or carbonic ester groups in the main chain
D03D 15/00 - Woven fabrics characterised by the material, structure or properties of the fibres, filaments, yarns, threads or other warp or weft elements used
A61F 13/08 - Elastic stockingsBandages or dressingsAbsorbent pads specially adapted for feet or legsCorn-padsCorn-rings for contracting aneurisms
D01F 6/70 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from homopolycondensation products from polyurethanes
82.
Method and system for spatial-temporal denoising and demosaicking for noisy color filter array videos
A method for spatial-temporal denoising and demosaicking for noisy color filter array (CFA) video, the method including applying spatial-temporal CFA video denoising (11) to the CFA video in order to generate a denoised CFA, applying initial color demosaicking (CDM) (19) to the denoised CFA video in order to generate a demosaicked video, and applying spatial-temporal post-processing (26) to the demosaicked video in order to reduce CDM artifacts and CDM errors and enhance the quality of the video.
An apparatus for detecting the presence of a microorganism in a sample includes a housing that includes a base fixed with a first DNA primer having a nucleotide sequence that is complementary to a DNA sequence of the microorganism of interest, a fibrinogen-splitting agent that is bound with a second DNA primer having a nucleotide sequence that is also complementary to a DNA sequence of the microorganism of interest, a rinsing unit configured to rinse the housing; and a fibrinogen adding unit configured to add fibrinogen to the housing so that the fibrinogen chemically reacts with the fibrinogen-splitting agent to produce a viscous substance, an ultrasonic emitter configured to emit ultrasonic signal to the housing, and an ultrasonic receiver configured to receive ultrasonic signal from the housing and transmit the received ultrasonic signal to an ultrasonic analyzer, wherein the ultrasonic analyzer determines whether the microorganism of interest exists.
A system for extracting finger vein and finger texture images from a finger of a person at the same time, the device including an image capture device configured to capture at least one image of at least one finger in a contactless manner, a feature extraction module configured to extract unique finger vein features and finger texture features from the at least one captured image, and a processing module configured to normalize the at least one captured image and integrate the extracted finger vein features and finger texture features.
A switched reluctance motor includes an inner stator having a plurality of stator poles with coil windings, the inner stator having a plurality of stator phases, an outer rotor configured to rotate around the inner stator, the outer rotor having a plurality of rotor poles, at least one position sensor configured to detect a position of the outer rotor, and a DC supply configured to sequentially supply current to excite the stator phases.
A method of fabricating Fiber Bragg gratings in a micro/nanofiber using ultrashort pulse irradiation, the method includes elongating and flame-brushing a single mode optical fiber to create a micro/nanofiber, and generating the ultrashort pulse irradiation to induce a plurality of refractive index changes at predetermined intervals within the micro/nanofiber, wherein the ultrashort pulse propagates through a focusing element and a diffractive element prior to propagating on the micro/nanofiber.
An optical fiber with long period fiber gratings includes an optical fiber axis, a core region extending along the fiber axis, the core region having a core refractive index, a cladding region surrounding the core region, the cladding having a cladding refractive index, and a plurality of microholes perpendicular to the fiber axis with a portion of the core region removed, the plurality of microholes are spaced apart by a grating period.
A method for achieving fast and efficient measurement of path capacity of a communication network. The method includes the following steps: (a) transmitting a number of probes from a local endpoint to a remote endpoint over a network path and each probe contains at least two outgoing packets and each probe can elicit at least two response packets from the remote endpoint; (b) determining a first minDelay by measuring RTT between the time sending the first probe packet and the time receiving the first response packet; (c) determining a second minDelay by measuring RTT between the time sending the second probe packet and the time receiving the second response packet; and (d) determining a minimum delay difference by subtracting said first minDelay from said second minDelay. The minimum delay difference divided by packet size can be used as a measurement of the network path capacity.
A measurement device (10) for quantitatively measuring stiffness, torque or range of motion (ROM) around the joint axis of the ankle-foot complex of a lower limb in the sagittal and coronal planes, the device (10) comprising: a plate (13, 21) for placement of the ankle-foot complex, the plate (13, 21) operatively connected to an actuator (14, 16) for manual actuation; an angular measurement device (12, 17) to measure an angular position of the ankle-foot complex; a torquemeter (11) to measure resistance torque of the ankle-foot complex; an electromyograph (48) to monitor muscular activity of muscles of the lower limb; and computer software to record the measured angular position, resistance torque of the ankle-foot complex and EMG of the lower limb muscles.
A single fiber Mach-Zehnder interferometer comprises an optical fiber having a core region and a cladding surrounding the core region, and a micro-cavity having part of the cladding and the core region removed, wherein the micro-cavity is adapted to receive a light beam and separate the light beam into a first light beam that propagates through the micro-cavity in an unguided mode, and a second light beam that propagates through the core region in a guided mode.
A method of fabricating silicone composite with a layer of antimicrobial coating, the method includes forming an antimicrobial mixture by adding a calculated amount of antimicrobial agent to a solution of water and alcohol, depositing the antimicrobial mixture in a container with a thickness of 0.1 μm to 10 μm, evaporating the water and alcohol of the antimicrobial mixture to form the layer of antimicrobial coating, adding silicone resin on top of the layer of antimicrobial coating and allow the silicone resin to permeate and crosslink with the layer of antimicrobial coating and removing the silicone composite with the layer of antimicrobial coating from the container.
B32B 9/04 - Layered products essentially comprising a particular substance not covered by groups comprising such substance as the main or only constituent of a layer, next to another layer of a specific substance
A61L 2/232 - Solid substances, e.g. granules, powders, blocks, tablets layered or coated
B05D 1/36 - Successively applying liquids or other fluent materials, e.g. without intermediate treatment
B28B 5/00 - Producing shaped articles from the material in moulds or on moulding surfaces, carried or formed by, in or on conveyors irrespective of the manner of shaping
92.
Method and system for encoding and decoding low-density-parity-check (LDPC) codes
An approximated lower-triangle structure for the parity-check matrix of low-density parity-check (LDPC) codes which allows linear-time-encoding complexity of the codes is disclosed, and the parity part of the parity-check matrix is semi-deterministic which allows high flexibility when designing the LDPC codes in order to provide higher error-correction capabilities than a typical dual-diagonal structure.
H03M 13/00 - Coding, decoding or code conversion, for error detection or error correctionCoding theory basic assumptionsCoding boundsError probability evaluation methodsChannel modelsSimulation or testing of codes
93.
Electronic stimulation textile for traditional Chinese medicine therapy
A textile for providing traditional Chinese medicine therapy to a wearer using electronic stimulation includes at least two conductive paths that are made from conductive textile material, the conductive paths are separated by nonconductive textile material, at least one pair of electrodes attach to the conductive paths corresponding to specific part of body or acupoints according to traditional Chinese medicine theory, and an electronic stimulation signal controller configured to conduct electronic stimulation signals to the electrodes via the conductive paths.
A Capacitive Micromachined Ultrasonic Transducer (CMUT) having a membrane operatively connected to a top electrode and having a bottom electrode having a concave void. When a DC bias voltage is applied, the membrane is deflected towards the bottom electrode such that a peripheral edge region of the membrane is brought into close proximity with the bottom electrode and an electrostatic force proximal to the peripheral edge region of the membrane is increased.
A system for bonding electrical devices using an electrically conductive adhesive to adhere the electrical devices together, the system comprising: an ultrasonic transducer to generate an ultrasonic vibration; and an ultrasonic to thermal energy apparatus operatively attached to and covering an operational end of the ultrasonic transducer, the ultrasonic to thermal energy apparatus damping the ultrasonic vibration to minimize ultrasonic vibration transmitted to a first electrical device and causing the conversion of the ultrasonic vibration to a heating pulse which is conducted through the first electrical device to the adhesive; wherein the adhesive is softened by the heating pulse to bond the electrical devices together.
A method of fabricating a porous metal-based biomaterial, the method includes dispersing microwave susceptors into organic solvent to form a homogeneous suspension, dispersing bioactive fillers into organic solvent to form a homogeneous solution, mixing metal powder with the homogeneous solution and the homogeneous suspension to form a mixture, cold-pressing the mixture into a compact with predefined shape and size, placing the compact in a sintering container, and emitting microwave to heat the compact and remove the organic solvent resided in the compact at the same time.
A detection system (5) for assisting a driver when driving a vehicle, the system (5) comprising: a plurality of image capturing devices (98) mounted to the vehicle to capture images of the external environment of the vehicle; an image processing module (95) to identify potential hazards in real-time from the captured images and to superimpose information of the external environment relating to the identified potential hazards; and at least one display device (92) to display images processed by the image processing module in real-time; wherein the superimposed information is provided in an area of the display device (92) to ensure visual clarity of the images of the external environment.
A rehabilitation system for training hand movement of a user, the system comprising: a platform to be attached to the hand of the user; a plurality of finger assemblies operatively connected to the platform, each finger assembly having: a motor, a proximal follower assembly for a metacarpophalangeal (MCP) joint having a proximal rail guide operatively connected to the motor, and an intermediate follower assembly for a proximal interphalangeal (PIP) joint having an intermediate rail guide operatively connected to the proximal follower assembly; wherein a knuckle joint indicator of the proximal rail guide corresponds to a first virtual center and knuckle joint indicator of the intermediate rail guide corresponds to a second virtual center, the alignment of the knuckle joint indicators to the virtual centers enable motion of the finger to be controlled and maintain rotational axes of the finger about each virtual center when the proximal and intermediate follower assemblies are actuated by the motor.
A method for quantifying an intention of movement of a user, the method comprising: extracting a mechanomyogram (MMG) signal in response to surface vibration of a muscle of the user; and averaging the MMG signal by calculating the MMG root mean squared (RMS) amplitude or frequency variance in a predetermined time window; where an increasing RMS amplitude of the MMG signal corresponds to increasing muscle voluntary contraction or a decreasing frequency variance of the MMG signal corresponds to increasing muscle voluntary contraction.
An optical fiber 200 with a high thermal resistance fiber Bragg grating (FBG) 130. Compared to existing FBG's, the invention provides greatly enhanced thermal stability, being stable up to 1200° C. The grating reflectivity and resonant wavelength are maintained for extended duration at high temperatures. The FBG is thus suitable in high temperature sensors. The high thermal resistance of the FBG is obtained in a method of pre-annealing the optical fiber 105 at high temperature prior to inscribing the FBG. The high thermal resistance is optionally enhanced in a post-FBG creation step of heat treating the optical fiber 105 and FBG.
