A solid particle comprising a coprecipitate of a metal or metalloid compound, and medetomidine or an enantiomer or salt of medetomidine, an antifouling and an antifouling paint formulation containing such particle, an antifouling coating obtained by use of the paint formulation, and an object having the coating on at least part of its surface. A method for preparing the particle and the formulation.
The present embodiments relate to a method for reducing or preventing attacks from marine woodborers on wood in marine environment by impregnating the wood with a composition comprising medetomidine, or an enantiomer, salt or base thereof.
A01N 25/02 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
The present embodiments relate to a method of producing an antifouling paint composition and to antifouling paint composition. The method comprises combining an acrylate-based polymer comprising at least one silyl ester bond with a reactive amide- and/or amine-containing antifouling agent and a monoisocyanate, and/or with an adduct between the reactive amide- and/or amine-containing antifouling agent and the monoisocyanate, to form an antifouling paint composition comprising the adduct. The antifouling paint composition has improved in-can stability due to reduced risk of gel formation and viscosity increase.
A solid particle comprising a coprecipitate of a metal or metalloid compound, and medetomidine or an enantiomer or salt of medetomidine, an antifouling and an antifouling paint formulation containing such particle, an antifouling coating obtained by use of the paint formulation, and an object having the coating on at least part of its surface. A method for preparing the particle and the formulation.
The present embodiments relate to a method for reducing or preventing attacks from marine woodborers on wood in marine environment by impregnating the wood with a composition comprising medetomidine, or an enantiomer, salt or base thereof.
A01N 25/02 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
The present embodiments relate to an antifouling polymer comprising a plurality of repeating units. At least a portion of the plurality of repeating units comprises medetomidine, or an enantiomer, base or salt thereof, covalently bound to the repeating unit through a hydrolysable bond. The antifouling polymer can comprised in an antifouling composition applied as a surface coating on underwater or submersible structures to prevent or at least inhibit marine biofouling on surfaces of the structures.
The present embodiments relate to an antifouling polymer comprising a plurality of repeating units. At least a portion of the plurality of repeating units comprises medetomidine, or an enantiomer, base or salt thereof, covalently bound to the repeating unit through a hydrolysable bond. The antifouling polymer can comprised in an antifouling composition applied as a surface coating on underwater or submersible structures to prevent or at least inhibit marine biofouling on surfaces of the structures.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Paints, varnishes, lacquers; preservatives against rust in the nature of a coating and preservatives against deterioration of wood; colorants; mordant dyes; raw natural resins; metals in foil and powder form for painters, decorators, printing, and artists Preparations for destroying vermin; fungicides, herbicides; biocides for combating the growth of algae and organisms on boats
The present embodiments relate to an antifouling article comprising polyurethane and medetomidine, or an enantiomer or salt thereof, from 0.1% by weight of the antifouling article and present in a polymer matrix of the polyurethane.
B05D 1/02 - Processes for applying liquids or other fluent materials performed by spraying
B05D 3/10 - Pretreatment of surfaces to which liquids or other fluent materials are to be appliedAfter-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials by other chemical means
C08G 18/76 - Polyisocyanates or polyisothiocyanates cyclic aromatic
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Paints; varnish; preservatives against rust and against
deterioration of wood; colorants; mordants; raw natural
resins; metals in foil and powder form for painters,
decorators, printers and artists. Preparations for destroying vermin; antifungal preparations;
herbicides; biocides for counteracting fouling on boats
caused by algae and animals.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Paints; varnish; preservatives against rust in the nature of a coating and against deterioration of wood; colorants; mordant dyes; raw natural resins; metals in foil and powder form for painters, decorators, printers and artists Preparations for destroying vermin; antifungal preparations; herbicides; biocides for counteracting fouling on boats caused by algae and animals
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Paints; Varnish; Preservatives against rust and against deterioration of wood; Colorants; Mordants; Raw natural resins; Metals in foil and powder form for painters, decorators, printers and artists. Preparations for destroying vermin; Antifungal preparations; Herbicides; Biocides for counteracting fouling on boats caused by algae and animals.
The present embodiments relate to an antifouling article comprising polyurethane and medetomidine, or an enantiomer or salt thereof, from 0.1 % by weight of the antifouling article and present in a polymer matrix of the polyurethane.
A compound of formula (I) or a salt thereof for use in controlling parasitic crustaceans, such as sea lice, on fish, e.g. salmon. A method of improving water flow into and out of a cage or net for fish farming, by providing said cage or net with a surface coating containing a compound of formula (I) or a salt thereof in an amount effective to reduce biofouling of said cage or net. The coating is capable of releasing the compound or a salt thereof into the water in the cage or net in an amount effective to reduce or prevent parasitic infestation of the fish in the cage or net.
A01N 43/80 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms, as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
There is provided a process for the preparation of a compound of formula (I) as defined herein, wherein said process comprises reacting a compound of formula (II) as defined s herein with one or more suitable Vilsmeier reagent.
C07C 45/62 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atomsPreparation of chelates of such compounds by reactions not involving the formation of C=O groups by hydrogenation of carbon-to-carbon double or triple bonds
C07C 309/24 - Sulfonic acids having sulfo groups bound to acyclic carbon atoms of a carbon skeleton containing six-membered aromatic rings
C07D 233/00 - Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
C07C 45/45 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atomsPreparation of chelates of such compounds by condensation
C07C 45/63 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atomsPreparation of chelates of such compounds by reactions not involving the formation of C=O groups by introduction of halogenPreparation of compounds having C=O groups bound only to carbon or hydrogen atomsPreparation of chelates of such compounds by reactions not involving the formation of C=O groups by substitution of halogen atoms by other halogen atoms
C07F 9/14 - Esters of phosphoric acids containing P-halide groups
C07D 233/64 - Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
C07C 249/02 - Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
C07C 47/232 - Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing six-membered aromatic rings, e.g. phenylacetaldehyde having unsaturation outside the aromatic rings
C07C 47/24 - Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing halogen
C07C 47/228 - Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing six-membered aromatic rings, e.g. phenylacetaldehyde
16.
MEDETOMIDINE FOR USE IN CONTROLLING PARASITIC CRUSTACEANS ON FISH
Medetomidine or a salt thereof for use in controlling parasitic crustaceans, such as sea lice, on fish, e.g. salmon. A method of improving water flow into and out of a cage or net for fish farming, by providing said cage or net with a surface coating containing medetomidine or a salt thereof in an amount effective to reduce biofouling of said cage or net. The coating is capable of releasing medetomidine or the salt thereof into the water in the cage or net in an amount effective to reduce or prevent parasitic infestation of the fish in the cage or net.
The present invention relates to the use of medetomidine having a relatively higher amount of dexmedetomidine, or a salt or solvate thereof, as compared to levomedetomidine, as a marine antifouling agent. It further relates to surface coating compositions comprising such medetomidine, surfaces coated with such medetomidine, and methods for preventing marine biofouling using such medetomidine.
The present invention relates to the use of medetomidine having a relatively higher amount of levomedetomidine, or a salt or solvate thereof, as compared to dexmedetomidine, as a marine antifouling agent. It further relates to surface coating compositions comprising such medetomidine, surfaces coated with such medetomidine, and methods for preventing marine biofouling using such medetomidine.
There is provided a novel process for the preparation of a compound of formula (I), (Formula (I)). There is also provided novel processes to intermediates of the compound of formula (I), as well as novel intermediates themselves.
C07D 233/58 - Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
C07C 45/63 - Preparation of compounds having C=O groups bound only to carbon or hydrogen atomsPreparation of chelates of such compounds by reactions not involving the formation of C=O groups by introduction of halogenPreparation of compounds having C=O groups bound only to carbon or hydrogen atomsPreparation of chelates of such compounds by reactions not involving the formation of C=O groups by substitution of halogen atoms by other halogen atoms
C07C 47/24 - Unsaturated compounds having —CHO groups bound to acyclic carbon atoms containing halogen
C07C 47/11 - Saturated compounds having —CHO groups bound to acyclic carbon atoms or to hydrogen containing rings monocyclic
01 - Chemical and biological materials for industrial, scientific and agricultural use
02 - Paints, varnishes, lacquers
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Chemicals used in industry, yet not for use in adhesive
industry, science and photography, as well as in
agriculture, horticulture and forestry; unprocessed
artificial resins; unprocessed plastics; manures; fire
extinguishing compositions; tempering and soldering
preparations; chemical substances for preserving foodstuffs;
tanning substances. Paints, varnishes, lacquers; preservatives against rust and
against deterioration of wood; colorants; mordants; raw
natural resins; metals in foil and powder form for painters,
decorators, printers and artists. Preparations for destroying vermin; fungicides, herbicides;
biocides for combating the growth of algae and organisms on
boats.
The present disclosure relates to a process for the preparation of medetomidine, 4-[1-(2,3-Dimethylphenyl)ethyl]- 1H-imidazoIe in an environmentally favourable and commercially feasible manner. Previous methods for the preparation of medetomidine use expensive 4-substituted imidazole derivatives as starting material. A practical way of synthesis is provided in which the imidazole ring is built up during a multi-step process starting from commercially affordable, 2,3-dimethylbenzoic. Mild reaction conditions are used throughout the process.
C07D 233/58 - Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
C07D 233/64 - Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
C07C 211/20 - Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic unsaturated carbon skeleton
01 - Chemical and biological materials for industrial, scientific and agricultural use
02 - Paints, varnishes, lacquers
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Chemicals used in industry, yet not for use in adhesive industry, science and photography, as well as in agriculture, horticulture and forestry; unprocessed artificial resins; unprocessed plastics; manures; fire extinguishing compositions; tempering and soldering preparations; chemical substances for preserving foodstuffs; tanning substances. Paints, varnishes, lacquers; preservatives against rust and against deterioration of wood; colorants; mordants; raw natural resins; metals in foil and powder form for painters, decorators, printers and artists. Preparations for destroying vermins; fungicides, herbicides; biocides for combating the growth of algae and organisms on boats.
