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Found results for
patents
1.
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Hypoestoxide, derivatives, related compounds, and agonists thereof for treatment or prevention of neurodegenerative diseases
| Application Number |
15556730 |
| Grant Number |
10857122 |
| Status |
In Force |
| Filing Date |
2016-02-03 |
| First Publication Date |
2018-04-19 |
| Grant Date |
2020-12-08 |
| Owner |
IMMUNE MODULATION, INC. (USA)
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| Inventor |
- Cottam, Howard
- Ojo-Amaize, Emmanuel
- Nchekwube, Emeka
- Oyemade, Olusola
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Abstract
New uses of hypoestoxide, its derivatives and related compounds for treatment and prevention of neurodegenerative diseases (e.g. Parkinsons disease, Alzheimers disease, Huntingtons disease) are described. More specifically, the invention relates to methods for treating various neurodegenerative diseases through administration of hypoestoxide, its derivatives and related compounds, or a combination thereof to a subject with a neurodegenerative disease such that the symptoms of the disease are treated or at least partially alleviated. Furthermore, the present invention further provides methods of preventing the development of neurodegenerative diseases in individuals who are predisposed to developing a neurodegenerative disease over time.
IPC Classes ?
- A61K 31/336 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
- A61P 25/16 - Anti-Parkinson drugs
- C07D 493/04 - Ortho-condensed systems
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2.
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HYPOESTOXIDE, DERIVATIVES, RELATED COMPOUNDS, AND AGONISTS THEREOF FOR TREATMENT OR PREVENTION OF NEURODEGENERATIVE DISEASES
| Document Number |
02978869 |
| Status |
In Force |
| Filing Date |
2016-02-03 |
| Open to Public Date |
2016-09-15 |
| Grant Date |
2023-09-19 |
| Owner |
IMMUNE MODULATION, INC. (USA)
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| Inventor |
- Cottam, Howard
- Ojo-Amaize, Emmanuel
- Nchekwube, Emeka
- Oyemade, Olusola
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Abstract
New uses of hypoestoxide, its derivatives and related compounds for treatment and prevention of neurodegenerative diseases (e.g. Parkinsons disease, Alzheimers disease, Huntingtons disease) are described. More specifically, the invention relates to methods for treating various neurodegenerative diseases through administration of hypoestoxide, its derivatives and related compounds, or a combination thereof to a subject with a neurodegenerative disease such that the symptoms of the disease are treated or at least partially alleviated. Furthermore, the present invention further provides methods of preventing the development of neurodegenerative diseases in individuals who are predisposed to developing a neurodegenerative disease over time.
IPC Classes ?
- A61K 31/336 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
- A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- C07D 303/02 - Compounds containing oxirane rings
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3.
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HYPOESTOXIDE, DERIVATIVES, RELATED COMPOUNDS, AND AGONISTS THEREOF FOR TREATMENT OR PREVENTION OF NEURODEGENERATIVE DISEASES
| Application Number |
US2016016294 |
| Publication Number |
2016/144441 |
| Status |
In Force |
| Filing Date |
2016-02-03 |
| Publication Date |
2016-09-15 |
| Owner |
IMMUNE MODULATION, INC. (USA)
|
| Inventor |
- Cottam, Howard
- Ojo-Amaize, Emmanuel
- Nchekwube, Emeka
- Oyemade, Olusola
|
Abstract
New uses of hypoestoxide, its derivatives and related compounds for treatment and prevention of neurodegenerative diseases (e.g. Parkinsons disease, Alzheimers disease, Huntingtons disease) are described. More specifically, the invention relates to methods for treating various neurodegenerative diseases through administration of hypoestoxide, its derivatives and related compounds, or a combination thereof to a subject with a neurodegenerative disease such that the symptoms of the disease are treated or at least partially alleviated. Furthermore, the present invention further provides methods of preventing the development of neurodegenerative diseases in individuals who are predisposed to developing a neurodegenerative disease over time.
IPC Classes ?
- A61K 31/336 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
- C07D 303/02 - Compounds containing oxirane rings
- A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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4.
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DERIVATIVES OF HYPOESTOXIDES FOR THE TREATMENT OF MALARIA
| Application Number |
US2008012708 |
| Publication Number |
2010/056223 |
| Status |
In Force |
| Filing Date |
2008-11-13 |
| Publication Date |
2010-05-20 |
| Owner |
IMMUNE MODULATION, INC. (USA)
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| Inventor |
- Cottam, Howard, B.
- Ojo-Amaize, Emmanuel, A.
- Nchekwube, Emeka, J.
- Oyemade, Olusola, A.
- Nchekwube, Donna, G.
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Abstract
Novel diterpene compounds, in particular, hypoestoxide- related compounds, are provided in pure form or as contained in the native plant source, for treatment and prophylaxis of cancer, inflammatory diseases, hyperlipidemias, malaria, and diabetes mellitus. Embodiments also pertain to methods for using the hypoestoxide-related compounds to treat various diseases and symptoms associated with those diseases.
IPC Classes ?
- A61K 31/336 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having three-membered rings, e.g. oxirane, fumagillin
- A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A61P 33/06 - Antimalarials
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