The invention relates to a system for collecting animal semen, comprising an artificial vagina (2) having an internal space (8) for collecting the semen (5) delimited by a widened first end (6) and a narrowed second end (7), and a collecting tube (3) having an introduction opening (9) and configured to be partially inserted, via its opening, into the vagina, via its narrowed second end, the narrowed second end having a narrowed inner diameter of between about 27 mm and about 28 mm, the collecting tube being a standard laboratory tube having a standard outer diameter greater than the narrowed inner diameter of the artificial vagina at the narrowed second end thereof, and the artificial vagina being at least partially elastically deformable at its narrowed second end such that the internal space of the artificial vagina leads directly into the introduction opening of the collecting tube.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
37 - Construction and mining; installation and repair services
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Pharmaceutical and veterinary products and preparations; biological media for the collection, filtration, preservation, freezing or thawing of animal embryos or microorganisms;
(2) Veterinary apparatus and instruments for animal artificial insemination; (1) Installation, maintenance and repair services for machines and apparatus used for animal artificial insemination;
(2) Veterinary services; animal artificial insemination services; veterinary advice in the field of animal reproduction and fertility; veterinary assistance and care; veterinary analyses and diagnostics; animal semen management services; animal health consultations; animal reproduction services.
01 - Chemical and biological materials for industrial, scientific and agricultural use
02 - Paints, varnishes, lacquers
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
Goods & Services
(1) Produits chimiques à usage scientifique et/ou de laboratoire; produits chimiques destinés à conserver des produits biologiques.
(2) Couleurs en poudre, notamment pour bouchage de paillettes de conditionnement de produits biologiques.
(3) Milieux liquides pour collecte, conservation, congélation ou décongélation d'embryons ou de micro-organismes du règne animal; véhicules aqueux pour micro-organismes du règne animal à maintenir vivants hors de leur milieu naturel; milieux destinés au lavage, à la filtration et/ou à la congélation des spermatozoïdes, ainsi qu'à la collecte d'ovocytes; milieux salins tamponnés (préparation à usage vétérinaire).
(4) Machines et appareils agitateurs et/ou mélangeurs notamment pour sperme ou pour sperme dilué, y compris agitateurs chauffants, agitateurs à balancement, agitateurs magnétiques, flacons (verrerie graduée); agitateurs (verrerie graduée); ampoules graduées; programmes informatiques et logiciels de gestion du fonctionnement de machines et installations de conditionnement de semence de paillettes et d'impression sur lesdites paillettes; programmes informatiques et logiciels de gestion d'opérations de collecte, de conditionnement, d'identification, de pré-stockage de produits biologiques, notamment de semence; programmes informatiques et logiciels de gestion du fonctionnement de machines de conditionnement et/ou de congélation de produits biologiques, notamment de semence; machines à compter les paillettes d'insémination artificielle.
(5) Appareils et instruments vétérinaires, y compris appareils, instruments et matériel de récolte et/ou collecte et/ou stockage et/ou conditionnement de semence et d'embryons et/ou pour insémination artificielle, y compris vagins artificiels, manchons protecteurs pour vagins artificiels, embouts coniques pour vagins artificiels, robinets pour vagins artificiels, étuis protecteurs pour vagins artificiels, électro-éjaculateurs, capotes, garnitures, récipients, couvercles, flacons et vases de récolte de semence, capuchons pour vases de récolte, filtres de collecte, gants de récolte; seringues pour paillettes d'insémination artificielle, tiges-pistons pour seringues, rondelles pour seringues, étuis pour seringues, pistolets d'insémination munis de dispositifs d'avertissement sonore, pistolets pompes, gaines de protection et chemises sanitaires pour les pistolets et seringues précités; sondes d'insémination, paillettes à usage vétérinaire; appareils, instruments et matériel de récolte et/ou transfert d'embryons, y compris sondes de collecte, sondes de prélèvement, tuyaux de collecte ou de prélèvement; gaines de transfert d'embryons, tuyaux en matière plastique et buses de remplissage à usage vétérinaire, notamment pour opérations de conditionnement de semence; sondes pour insémination artificielle et/ou pour traitements vaginaux ou utérins, enveloppes sanitaires à usage unique pour les sondes précitées, dispositifs de détection de l'état d'oestrus chez les animaux notamment chez les vaches; supports, étuis, pochettes et boîtiers pour les dispositifs précités.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
37 - Construction and mining; installation and repair services
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Pharmaceutical, veterinary products and preparations;
biological media for collecting, filtering, preserving,
freezing or thawing of embryos or micro-organisms of the
animal kingdom. Veterinary apparatus and instruments for artificial
insemination of animals. Installation, maintenance and repair of machines and
apparatus used for artificial insemination of animals. Veterinary services; animal artificial insemination
services; veterinary advice relating to animal fertility and
reproduction; veterinary care and assistance; veterinary
analyses and diagnostics; animal semen management services;
consultations with respect to animal health; animal
reproduction services.
7.
STRAW FOR PRESERVING A PREDETERMINED DOSE OF A SUBSTANCE AND ASSEMBLY COMPRISING SUCH A STRAW
The invention relates to a straw (1) for preserving a predetermined dose of a liquid-based substance, the straw comprising a tube (2) extending between a first end (3) and a second end (4) and defining an inner space (5), and a stopper (7) which is accommodated in the inner space (5), closer to the first end (3) than to the second end (4), the stopper (7) comprising an inner pad (10), an outer pad (11) which is at least twice as long as the inner pad (10), and a sealing member (12) positioned between the inner pad (10) and the outer pad (11) and which is configured to transform in contact with the substance into a liquid-tight paste or gel, the outer pad (11) being made of a first woven fibrous substance (15) and coated with an indicator component (16).
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
A61D 19/02 - Instruments or methods for reproduction or fertilisation for artificial insemination
B01J 20/281 - Sorbents specially adapted for preparative, analytical or investigative chromatography
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
8.
ARTIFICIAL INSEMINATION DEVICE FOR LIVESTOCK, IN PARTICULAR PIGS
The invention relates to an artificial insemination device (1) for livestock, in particular pigs, comprising a tubular body (2) and a tip (3) which is attached to one end (6) of the tubular body (2) and is configured to be inserted and positioned in the cervix of a female animal, characterised in that the tubular body (2) is formed by an inner shell (20) which is made of paper and at least partially delimits a flow channel (7) in the tubular body (2) for the flow of a male animal's semen, and an outer shell (27) made of a biopolymer material and covering the inner shell (20).
The invention relates to an artificial insemination device (1) for livestock, in particular pigs, comprising a tubular body (2) and a tip (3) which is attached to one end (6) of the tubular body (2) and is configured to be inserted and positioned in the cervix of a female animal, characterised in that the tip (3) is composed of at least agar-agar, water and glycerol.
The present invention relates to the use of a multilayer packaging, preferably a film or a pouch, for storing a semen extender, said packaging, preferably said film or said pouch, comprising polyethylene terephthalate, polyethylene or polyamide, aluminium and a desiccant.
B32B 15/085 - Layered products essentially comprising metal comprising metal as the main or only constituent of a layer, next to another layer of a specific substance of synthetic resin comprising polyolefins
B32B 15/09 - Layered products essentially comprising metal comprising metal as the main or only constituent of a layer, next to another layer of a specific substance of synthetic resin comprising polyesters
The invention relates in particular to a system for assisting in the artificial insemination of an animal, comprising a vaginal penetration device, provided with an image sensor, and a data processing unit, the system being configured for: - obtaining (500) at least one image of a view close to the cervix of the animal; - determining (515-1, 515-2, 515-n) a plurality of features of elements represented in said at least one image; - estimating (520) a fertility index of the animal on the basis of said plurality of features; and - transmitting (525) the estimated fertility index to a user of the vaginal penetration device.
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
A61B 1/303 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor for the vagina, i.e. vaginoscopes
12.
APPARATUS FOR ASSISTING IN VAGINAL PENETRATION AND WORK ASSEMBLY COMPRISING THIS APPARATUS AND A WORK TOOL
The apparatus, which is provided to receive a work tool (119), comprises: - a handle (121); - a speculum tube (123) extending from the handle (121) to a distal end at which it has an opening; - a video viewing system comprising an objective disposed within the speculum tube (123); and - an objective support to hold the objective in a predetermined position relative to the speculum tube (123); - said handle (121) comprises a handle core (152), a handle leg (153), and a handle rail (154); said handle core (152) having a passage for said work tool (119) between said handle rail (154) and said speculum tube (123); said handle rail (154) being configured to slidingly guide the work tool (119) in said speculum tube (123); said handle rail (154) being removably mounted in said apparatus (120). The work assembly comprises this apparatus and a work tool.
A61D 19/02 - Instruments or methods for reproduction or fertilisation for artificial insemination
A61B 17/43 - Gynaecological or obstetrical instruments or methods for reproduction or fertilisation for artificial insemination
A61B 1/32 - Devices for opening or enlarging the visual field, e.g. of a tube of the body
A61B 1/303 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor for the vagina, i.e. vaginoscopes
A61B 1/05 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor combined with photographic or television appliances characterised by the image sensor, e.g. camera, being in the distal end portion
A61B 1/06 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor with illuminating arrangements
A61B 1/018 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor characterised by internal passages or accessories therefor for receiving instruments
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
13.
INSEMINATION WORK TOOL AND WORK ASSEMBLY COMPRISING THIS TOOL AND AN APPARATUS FOR ASSISTING IN VAGINAL PENETRATION
The insemination work tool comprises an insemination gun (32), which is to be used with a straw for the preservation of a predetermined dose of liquid-based substance and in particular pure or diluted animal semen, and a gun extension (145). The work assembly comprises this insemination work tool and an apparatus for assisting in vaginal penetration, in particular for farm animals, provided to receive the insemination work tool.
A61D 19/02 - Instruments or methods for reproduction or fertilisation for artificial insemination
A61B 17/43 - Gynaecological or obstetrical instruments or methods for reproduction or fertilisation for artificial insemination
A61B 1/015 - Control of fluid supply or evacuation
A61B 1/018 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor characterised by internal passages or accessories therefor for receiving instruments
A61B 1/05 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor combined with photographic or television appliances characterised by the image sensor, e.g. camera, being in the distal end portion
A61B 1/06 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor with illuminating arrangements
A61B 1/303 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor for the vagina, i.e. vaginoscopes
14.
NOVEL COMPOSITIONS AND THEIR USE TO INCREASE MOTILITY, VIABILITY AND LIFESPAN OF SPERM CELLS AND FERTILITY
ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARIS (France)
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
SORBONNE UNIVERSITE (France)
Inventor
Schmitt, Eric
Carion, Olivier
Pipart, Perrine
Camugli, Sabine
Hourdet, Dominique
Tran, Yvette
Abstract
The present invention relates to novel compositions, process for manufacturing said compositions and use thereof for increasing motility, viability and lifespan of sperm cells, and fertility.
The invention relates to a unit provided with a temperature indicator component (41) made of thermochromic material, which adopts an initial state in which the unit (10) is empty and the indicator component has entirely a first appearance as long as its temperature remains below a high threshold, a nominal-service state in which the unit is filled with a dose of semen (27) and the indicator component has a first zone (50) having the first appearance and a second zone (51) having a second appearance as long as its temperature remains between a low threshold and the high threshold, and an irregular-service state in which the unit is filled with the dose of semen and the indicator component has entirely the first appearance or entirely the second appearance. The invention also relates to an assembly having such a unit and a filling machine (55) provided with an activation station (56) for activating the temperature indicator component of the unit.
A61D 19/02 - Instruments or methods for reproduction or fertilisation for artificial insemination
G01K 11/12 - Measuring temperature based on physical or chemical changes not covered by group , , , or using changes in colour, translucency or reflectance
16.
Support for analysing by microscope a liquid-based biological substance and system comprising such a support and a microscope
The support comprises an object-carrying slide (11) and a cover glass (12) secured by lines of adhesive (13) peripherally defining individual compartments (14) for receiving a sample of the biological substance; characterised in that the upper face (17) of the object-carrying slide is bare and uncovered over at least one front marginal region (41) and at least one rear marginal region (42), each having an extension in the front-rear direction equal to at least 2.5 mm and an extension in the left-right direction equal to at least the distance between the respective axes of the two individual compartments furthest apart from one another. The system comprises the support (40) and a microscope for enclosing the support between a stage and a support plate provided with fingers, the distal ends of which are in contact with the marginal regions (41, 42) exclusively.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (France)
SWISSGENETICS (Switzerland)
Inventor
Arnoult, Christophe
Schmitt, Eric
Martinez, Guillaume
Escoffier, Jessica
Abstract
The invention relates to a method for increasing the lifespan of animal sperm comprising contacting said sperm with an inhibitor of Slo3 potassium channel.
The invention also relates to a use of an inhibitor of Slo3 potassium channel, for increasing the lifespan of animal sperm or motility of capacitated animal sperm, comprising contacting an inhibitor of Slo3 potassium channel with said sperm. Moreover, the invention relates to an artificial insemination instrument for use in artificial insemination of an animal, comprising animal sperm in contact with an inhibitor of Slo3 potassium channel.
The invention also relates to a method for artificially inseminating an animal using said artificial insemination instrument.
Eventually, the invention relates to a method for increasing the fertility of an animal, comprising contacting sperm of said animal with an inhibitor of Slo3 potassium channel; then artificially inseminating said animal with said sperm.
The invention relates to a device for cryogenic freezing of units for packaging a biological substance comprising a receptacle (2) configured such that a stream of vapour of a cryogenic agent circulates therein, having at its top an insertion opening (10) for inserting the packaging units into the receptacle (2), a lid (3) that is able to move between a closed position in which it closes the insertion opening (10) and an open position in which it leaves the insertion opening (10) open, and a port (4) for discharging the vapour, provided in the receptacle (2), characterised in that the device (1) further comprises a stopper (13) mechanically connected to the lid (3) such that, when the lid (3) is in the closed position, the stopper (13) is spaced apart from the port (4) and, when the lid (3) is in the open position, the stopper (13) closes the port (4).
The assembly comprises a ramp (4) and a straw transfer device (60) comprising two lateral pads and a straw (1) collector arranged between the two lateral pads, the freezer ramp (4) and the transfer device (60) being configured to allow a first end position, to allow a second end position, and such that, by sliding the transfer device (60) from the first end position to the second end position with the pads that slide on angled sections (19) of the ramp (4), the plurality of straws (1) initially arranged on the ramp (4) is recovered in the collector of the transfer device (60).
Assembly for handbag multiple straws for packaging animal semen, each having a predetermined diameter and a predetermined length, comprising a freezing ramp (4) that has a rim and a bottom surrounding a central free space (5), said bottom comprising two toothed walls (11, 25) which extend longitudinally along said central free space (5), each torn lied wall (11.25) having a toothing at its top, the toothings of said toothed walls (11, 25) being identical, with each trough being delimited by a surface having a curvature along said predetermined diameter, characterized in that it further comprises a crosspiece (100) comprising parts (103, 104) that are able to move with respect to one another and are configured to permit a position in which said crosspiece (100) is removably joined to said freezing ramp (4) at a location provided to receive at least one said straw (1).
A support element for a plurality of packaging straws, the support element comprising a plate (31) and two flanges (37) rigidly connected to said plate (31) and comprising a fluted surface (53) having a plurality of similar grooves (36), each flange (37) comprising a central part as well as a first projecting part (42) and a second projecting part (43), each extending from one side of the central part, characterised in that the first projecting part comprises a bracket (42) having a bearing face and the second projecting part comprises another bracket (43) having another bearing face, said bearing face and said other bearing face being upwards facing and, in the direction of height, said bearing face being further from said plate (31) than said other bearing face. The assembly comprises the support element and a freezing rack (4).
The support comprises an object-carrying slide (11) and a cover glass (12) secured by lines of adhesive (13) peripherally defining individual compartments (14) for receiving a sample of the biological substance; characterised in that the upper face (17) of the object-carrying slide is bare and uncovered over at least one front marginal region (41) and at least one rear marginal region (42), each having an extension in the front-rear direction equal to at least 2.5 mm and an extension in the left-right direction equal to at least the distance between the respective axes of the two individual compartments furthest apart from one another. The system comprises the support (40) and a microscope for enclosing the support between a stage and a support plate provided with fingers, the distal ends of which are in contact with the marginal regions (41, 42) exclusively.
The invention relates to a device for cryogenic freezing of units for packaging a biological substance comprising a receptacle (2) configured such that a stream of vapour of a cryogenic agent circulates therein, having at its top an insertion opening (10) for inserting the packaging units into the receptacle (2), a lid (3) that is able to move between a closed position in which it closes the insertion opening (10) and an open position in which it leaves the insertion opening (10) open, and a port (4) for discharging the vapour, provided in the receptacle (2), characterised in that the device (1) further comprises a stopper (13) mechanically connected to the lid (3) such that, when the lid (3) is in the closed position, the stopper (13) is spaced apart from the port (4) and, when the lid (3) is in the open position, the stopper (13) closes the port (4).
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Biological media, particularly for preserving fresh or
frozen semen and/or for embryo collection and transfer;
filtering media for medical and/or veterinary use; liquid
media for collecting, preserving, freezing or thawing of
embryos or microorganisms of the animal kingdom; aqueous
vehicles for micro-organisms of the animal kingdom to be
kept alive outside their natural environment; media for
washing, filtration and/or freezing of sperm, as well as for
the collection of oocytes. Veterinary apparatus for use in animal semen collection;
tubes called straws for cryogenic preservation of biological
samples; straws for veterinary use; identification sheaths
and cases for the aforesaid straws.
25.
Appliance for assisting in vaginal penetration and provided to receive a working tool
An appliance includes a handle, a speculum tube extending axially from the handle as far as a distal end where it has an opening, a video viewing system having a lens arranged in the speculum tube and a transmission device connected to the lens and connectable to a remote viewing screen, and a lens support for keeping the lens in a predetermined position with respect to the speculum tube, in which position the lens is near the opening and opposite the space situated beyond the opening, characterized in that the speculum tube has an end part and a main part extending between the end part and the handle, the end part being arranged around the support and delimiting the opening, the end part being elastically deformable and the main part being rigid.
A61B 1/303 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor for the vagina, i.e. vaginoscopes
A61D 19/02 - Instruments or methods for reproduction or fertilisation for artificial insemination
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
A61B 1/018 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor characterised by internal passages or accessories therefor for receiving instruments
A61B 1/05 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor combined with photographic or television appliances characterised by the image sensor, e.g. camera, being in the distal end portion
26.
ASSEMBLY FOR HANDLING A PLURALITY OF ANIMAL SEMEN PACKAGING STRAWS
The assembly comprises a ramp (4) and a straw transfer device (60) comprising two lateral pads and a straw (1) collector arranged between the two lateral pads, the freezer ramp (4) and the transfer device (60) being configured to allow a first end position, to allow a second end position, and such that, by sliding the transfer device (60) from the first end position to the second end position with the pads that slide on angled sections (19) of the ramp (4), the plurality of straws (1) initially arranged on the ramp (4) is recovered in the collector of the transfer device (60).
Assembly for handling multiple straws for packaging animal semen, each having a predetermined diameter and a predetermined length, comprising a freezing ramp (4) that has a rim and a bottom surrounding a central free space (5), said bottom comprising two toothed walls (11, 25) which extend longitudinally along said central free space (5), each toothed wall (11, 25) having a toothing at its top, the toothings of said toothed walls (11, 25) being identical, with each trough being delimited by a surface having a curvature along said predetermined diameter, characterized in that it further comprises a crosspiece (100) comprising parts (103, 104) that are able to move with respect to one another and are configured to permit a position in which said crosspiece (100) is removably joined to said freezing ramp (4) at a location provided to receive at least one said straw (1).
A support element for a plurality of packaging straws, the support element comprising a plate (31) and two flanges (37) rigidly connected to said plate (31) and comprising a fluted surface (53) having a plurality of similar grooves (36), each flange (37) comprising a central part as well as a first projecting part (42) and a second projecting part (43), each extending from one side of the central part, characterised in that the first projecting part comprises a bracket (42) having a bearing face and the second projecting part comprises another bracket (43) having another bearing face, said bearing face and said other bearing face being upwards facing and, in the direction of height, said bearing face being further from said plate (31) than said other bearing face. The assembly comprises the support element and a freezing rack (4).
A device for preserving a predetermined dose of liquid-based substance, notably animal semen or a preservation medium containing embryos or tissue samples, comprises a tube (11) made of a weldable plastics material. The tube allows a service state in which a receiving portion (21) intended to contain the said predetermined dose has a circular cross-section whereas a sealing portion (22) comprises a welded pinch (19) and a transition zone (23). Over at least part of the sealing portion a differentiating edge region (28) gives the external surface of the tube a visual appearance different from the visual appearance of the external surface of the tube outside of the differentiating edge region. A range comprises such a device and a similar device but without the differentiating edge region.
Bag/pouch for packaging of diluted animal semen suitable for
artificial insemination, particularly of porcine species
(artificial insemination apparatus for animals).
31.
Straw for the preservation of a predetermined dose of liquid-based substance
The straw comprises a tube (11) and a gas-permeable liquid-tight stopper (12), which stopper is disposed in the tube closer to one end (16) of the tube than another end (17) of the tube, which tube and which stopper are configured for the stopper to be able to slide in the tube towards the other end (17), said tube being transparent or translucent, said stopper comprising an identifier component (13) configured to emit, when it is illuminated with ultraviolet light, light of which the spectrum comprises at least one peak having a crest of predetermined wavelength in visible light, whereas when it is illuminated by visible light said identifier component does not emit said light of which the spectrum comprises said peak.
A61D 19/02 - Instruments or methods for reproduction or fertilisation for artificial insemination
A01N 1/147 - Carriers for immersion in cryogenic fluid for slow freezing or vitrification
A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
32.
Straw for cryogenic preservation of a dose of liquid-based substance, assembly comprising same, and method for empty this straw
A straw includes a tube (11), a stopper (13) arranged in the tube and having a passage (35) extending through it, and an emptying needle (14) having a first portion (31) protruding from the stopper as far as a distal end (19) situated in the tube, and a second portion (32) situated in the passage (35) of the stopper, the needle and the stopper forming an insert (12) entirely disposed in the tube and having an internal conduit (24) fluidically connecting the internal spaces of the tube that are situated to either side of the insert, the internal conduit being formed at least in part by the needle. A method for emptying the straw includes establishing a fluidic communication between the needle and a receptacle, and making an opening in the tube in order to connect the dose of liquid-based substance to the atmosphere and allow it to flow.
(1) Sachet/poche de conditionnement de semence animale diluée convenant pour l'insémination artificielle, en particulier des espèces porcines (appareils d'insémination artificielle pour animaux).
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (France)
SWISSGENETICS (Switzerland)
Inventor
Arnoult, Christophe
Schmitt, Eric
Martinez, Guillaume
Escoffier, Jessica
Abstract
The invention relates to a method for increasing the lifespan of animal sperm comprising contacting said sperm with an inhibitor of Slo3 potassium channel. The invention also relates to a use of an inhibitor of Slo3 potassium channel, for increasing the lifespan of animal sperm or motility of capacitated animal sperm, comprising contacting an inhibitor of Slo3 potassium channel with said sperm. Moreover, the invention relates to an artificial insemination instrument for use in artificial insemination of an animal, comprising animal sperm in contact with an inhibitor of Slo3 potassium channel. The invention also relates to a method for artificially inseminating an animal using said artificial insemination instrument. Eventually, the invention relates to a method for increasing the fertility of an animal, comprising contacting sperm of said animal with an inhibitor of Slo3 potassium channel; then artificially inseminating said animal with said sperm.
The invention concerns a cryogenic system (1) for vitrifying a substance comprising biological material to be preserved in a receiving region of a thin tube (8), comprising a tank (10) containing a bath (11) of a cryogenic agent and a support member (80) mounted on said tank in a predetermined first position in which said tube is orientated upright, the receiving region being immersed in a liquid zone (17) of said bath, and an opening of said tube being situated above said bath, in a zone of ambient air above said bath, in order to introduce the substance into the tube, the support member being mounted on said tank in a second predetermined position, in which said receiving region is immersed in the liquid zone and said opening is situated immediately above said liquid zone, in a gaseous zone (18) of said bath above said liquid zone and below said zone of ambient air, and being raised from said second position.
The device (1) comprises an inlet element (28) comprising an interface (40) for connecting to an artificial vagina and delimiting an inlet opening (14), a filter delimiting with the inlet element (28) an inlet chamber (41) on the side of the filter turned towards the opening (14) and a collection bag (4) extending between a closed end (8) and an open end (7) in which said inlet element is engaged; said bag and said filter delimiting a collection chamber (42) on the side of the filter turned towards the end (8); by means of which the semen entering through the opening (14) passes through the filter and comes to the collection chamber (42); the filter being a perforated wall (30) having a tubular portion (22) and a bottom portion (15) closing said tubular portion, and having a surface density of orifices (24) that is greater on said bottom portion than on said tubular portion.
A61D 19/02 - Instruments or methods for reproduction or fertilisation for artificial insemination
A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
The device (1) comprises an inlet element (28) comprising an interface (40) for connecting to an artificial vagina and delimiting an inlet opening (14), a filter associated with the inlet element (28) and delimiting therewith an inlet chamber (41) on the side of a first face of the filter turned towards the opening (14) and a collection bag (4) extending between a closed end (8) and an end (7) having an opening (6) in which said inlet element is engaged; said bag and said filter delimiting a collection chamber (42) on the side of the second face (18) of the filter turned towards the end (8); by means of which semen entering through the opening (14) passes through the filter and is collected in the collection chamber (42); characterized in that the filter is formed by a perforated wall (30) in one piece with the inlet element.
The invention relates to a straw comprising a tube (11) and a gas-permeable and liquid-tight stopper (12), said stopper (12) being arranged in the tube (11), close to an end (16). The invention is characterised in that the stopper (12) comprises an indicator component (20) having a first pre-determined colour in the absence of previous contact with said substance (21) and a second pre-determined colour, of a different shade from that of the first colour, once it has been in contact with said substance (21). The assembly comprises the straw (10) and a device (26) for controlling the filling of the straw.
G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
G01N 21/77 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
40.
METHOD FOR INCREASING THE LIFESPAN AND MOTILITY OF ANIMAL SPERM USING AN INHIBITOR OF SLO3 POTASSIUM CHANNEL
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (France)
SWISSGENETICS (Switzerland)
Inventor
Arnoult, Christophe
Schmitt, Eric
Martinez, Guillaume
Escoffier, Jessica
Abstract
The invention relates to a method for increasing the lifespan of animal sperm comprising contacting said sperm with an inhibitor of Slo3 potassium channel. The invention also relates to a use of an inhibitor of Slo3 potassium channel, for increasing the lifespan of animal sperm or motility of capacitated animal sperm, comprising contacting an inhibitor of Slo3 potassium channel with said sperm. Moreover, the invention relates to an artificial insemination instrument for use in artificial insemination of an animal, comprising animal sperm in contact with an inhibitor of Slo3 potassium channel. The invention also relates to a method for artificially inseminating an animal using said artificial insemination instrument. Eventually, the invention relates to a method for increasing the fertility of an animal, comprising contacting sperm of said animal with an inhibitor of Slo3 potassium channel; then artificially inseminating said animal with said sperm.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (France)
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (France)
SWISSGENETICS (Switzerland)
Inventor
Arnoult, Christophe
Schmitt, Eric
Martinez, Guillaume
Escoffier, Jessica
Abstract
The invention relates to a method for increasing the lifespan of animal sperm comprising contacting said sperm with an inhibitor of Slo3 potassium channel. The invention also relates to a use of an inhibitor of Slo3 potassium channel, for increasing the lifespan of animal sperm or motility of capacitated animal sperm, comprising contacting an inhibitor of Slo3 potassium channel with said sperm. Moreover, the invention relates to an artificial insemination instrument for use in artificial insemination of an animal, comprising animal sperm in contact with an inhibitor of Slo3 potassium channel. The invention also relates to a method for artificially inseminating an animal using said artificial insemination instrument. Eventually, the invention relates to a method for increasing the fertility of an animal, comprising contacting sperm of said animal with an inhibitor of Slo3 potassium channel; then artificially inseminating said animal with said sperm.
The appliance comprises a handle, a speculum tube (23) extending axially from the handle (21) as far as a distal end (22) where it has an opening (28), a video viewing system having a lens (35) arranged in the speculum tube and a transmission device (36) connected to the lens and connectable to a remote viewing screen, and a lens support (49) for keeping the lens (35) in a predetermined position with respect to the speculum tube, in which position the lens is near said opening (28) and opposite the space situated beyond said opening (28), characterized in that said speculum tube has an end part (26) and a main part (27) extending between said end part and said handle, said end part (26) being arranged around said support (49) and delimiting said opening (28), said end part (26) being elastically deformable and said main part (27) being rigid.
A61D 19/02 - Instruments or methods for reproduction or fertilisation for artificial insemination
A61B 1/303 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor for the vagina, i.e. vaginoscopes
43.
STRAW FOR CRYOGENIC PRESERVATION OF A DOSE OF LIQUID-BASED SUBSTANCE, ASSEMBLY COMPFRISING SAME, AND METHOD FOR EMPTYING THIS STRAW
The straw comprises a tube (11), a stopper (13) arranged in the tube and having a passage (35) extending through it, and an emptying needle (14) having a first portion (31) protruding from said stopper as far as a distal end (19) situated in said tube, and a second portion (32) situated in said passage (35) of the stopper, said needle and said stopper forming an insert (12) entirely disposed in said tube and having an internal conduit (24) fluidically connecting the internal spaces of said tube that are situated to either side of said insert, said internal conduit being formed at least in part by the needle. The assembly comprises the straw and a device configured to make an opening in the tube. The method comprises the steps of establishing a fluidic communication between the needle and a receptacle, then of making an opening in the tube in order to connect said dose of liquid-based substance to the atmosphere and allow it to flow.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
CENTRE HOSPITALIER UNIVERSITAIRE GRENOBLE ALPES (France)
Inventor
Arnoult, Christophe
Schmitt, Eric
Martinez, Guillaume
Ray, Pierre
Abstract
The invention relates to a La-1-like peptide agent that increases sperm motility. It is non-toxic and it may be used to treat male infertility in humans, and also to increase fertility in animals. It may be used in artificial reproductive techniques such as in vitro fertilisation (IVF), including intra-cytoplasmic sperm injection (ICSI). The La-1 like peptide agent may also be used in artificial insemination techniques such as intra-cytoplasmic uterine injection (IUI).
A61K 35/646 - Arachnids, e.g. spiders, scorpions, ticks or mites
A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
C07K 14/435 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
A61P 15/08 - Drugs for genital or sexual disordersContraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
Veterinary apparatus and instruments; imaging apparatus and
instruments for veterinary use; apparatus and instruments
for the creation of veterinary images; apparatus and
instruments for diagnostic imaging; apparatus and
instruments for diagnostic imaging for veterinary use;
scanners for veterinary use; ultrasound apparatus for
veterinary use; ultrasonic apparatus for veterinary use;
radiography apparatus and instruments for veterinary use;
X-ray apparatus and instruments for veterinary use;
electro-medical radiography apparatus and instruments;
medical radiography apparatus and instruments; x-ray
scanners for veterinary use; optical scanners for veterinary
use; digital scanners for veterinary use; image processing
apparatus and instruments for digital imaging in radiography
diagnostics; apparatus and instruments for analysis of
images for veterinary use; surgical, medical and dental
apparatus and instruments; parts and components for all the
aforesaid goods.
46.
Device for supply and positioning of straws for packaging animal semen and processing installation comprising such a device
The invention relates to a feeding and positioning device (5) for straws (2) for packing animal semen on a support (4), with a feeding hopper (20) having an inner space (21) which receives the straws and is partially delimited by an inclined and electrically conductive bottom wall (38), an evacuation chute (22) with an inlet orifice, which opens into said inner space, and with an outlet orifice opposite said support, a disentangling system (25) having an electrically conductive and movable part configured to come into contact with said straws and to set them in motion in said inner space, an electrically conductive support, and a mechanical connection interface of said movable part on said support, and electrical connection elements which are directly connected, respectively, to said bottom wall and said support and to said movable part and said support.
A61D 19/02 - Instruments or methods for reproduction or fertilisation for artificial insemination
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
B65B 51/10 - Applying or generating heat or pressure or combinations thereof
47.
Storage receptacle for straws for packaging animal semen and processing installation comprising such a receptacle
The invention relates to a storage receptacle (1) with a longitudinal opening (5) through which straws (2) for packing liquid-based substance are passed in a predetermined orientation of the straws, a housing (3) provided for the straws and configured to be inserted slidably in a cover (4) of the receptacle, the latter having an open configuration, in which the housing is partially inserted in the cover and the opening is free for the passage of the straws, and a closure configuration, in which the housing is inserted in the cover and the opening is closed by the cover in order to prohibit the passage of the straws. The housing has a parallelepipedal shape, a first front wall in which the opening is formed, a first bottom wall, two first longitudinal wails extending parallel to the opening, and two first side walls which each have two diagonals of a length less than or equal to the length of the straws.
The installation (1) comprises a treatment machine (12) and a supply and positioning device (16) configured to receive the straws (2) and dispose them one by one in a predetermined orientation for their treatment by said machine. The device (16) comprises a curved ramp (52) having a reception portion (64) for the straws (2) and an ejection portion (65) for the straws, the ramp being configured to convey, to the ejection portion (65), a straw (2) received on the reception portion (64) and sliding on the ramp (52), the ramp having a concave profile such that said profile has an orientation closer to the vertical in the reception portion (64) than in the ejection portion (65), such that a straw received on the reception portion (64) is accelerated to the ejection portion (65) at which the straw is guided and ejected with a predetermined orientation.
The invention concerns a cryogenic system (1) for vitrifying a substance comprising biological material to be preserved in a receiving region of a thin tube (8), comprising a tank (10) containing a bath (11) of a cryogenic agent and a support member (80) mounted on said tank in a predetermined first position in which said tube is orientated upright, the receiving region being immersed in a liquid zone (17) of said bath, and an opening of said tube being situated above said bath, in a zone of ambient air above said bath, in order to introduce the substance into the tube, the support member being mounted on said tank in a second predetermined position, in which said receiving region is immersed in the liquid zone and said opening is situated immediately above said liquid zone, in a gaseous zone (18) of said bath above said liquid zone and below said zone of ambient air, and being raised from said second position to said first position.
Sus scrofa), and preferably the composition is for use in artificial uterine insemination, and the process for artificial insemination preferably is uterine insemination.
Veterinary apparatus and instruments; Imaging apparatus and instruments for veterinary purposes; Apparatus and instruments for veterinary image formation; Diagnostic imaging apparatus and instruments; Diagnostic imaging apparatus and instruments for veterinary use; Scanners for veterinary use; ultrasound apparatus for veterinary use; Ultrasonic apparatus for veterinary use; Radiography apparatus and instruments for veterinary use; X-ray apparatus and instruments for veterinary use; Electro-medical x-ray apparatus and instruments; Medical x-ray apparatus and instruments; X-ray scanners for veterinary use; Optical scanners for veterinary use; Digital scanners for veterinary use; Image processing apparatus and instruments for digital imaging in x-ray diagnostics; Apparatus and instruments for analysing images for veterinary use; Surgical, medical and dental apparatus and instruments; Parts and fittings for all the aforesaid goods.
The straw (11) filling device comprises a casing body having a cavity (43) in which the needle (9) of a nozzle (7) is placed. The needle is inserted into the straw tube (12) received in the cavity. The casing body is attached to a carriage separately from the needle. The cavity comprises a distal opening located on the distal end side of the needle, a proximal opening located on the proximal end side of the needle, and a longitudinal opening extending from the distal opening to the proximal opening, thus enabling placement and removal of the needle in and out of the cavity in a direction transverse to the direction of the needle and preventing an adult finger accessing the distal end of the needle. The machine comprises a device of this type and a conveyor (2) designed to keep the straw tube in a filling position during each cycle.
The straw comprises a tube (11) and a stopper (12) fixed relative to the tube (11) and comprising a male connector tip (29) configured in order that a syringe needle (44) having a female connector tip (45) with a frusto-conical internal surface in accordance with a standard can be connected to said stopper (12) by engagement of the female connector tip (45) of the needle on the male connector tip (29) of the stopper (12).
The injection device comprises such a straw (10) and a syringe needle (44).
The method of emptying the straw comprises the step of pushing the dose of liquid-based substance (21) packaged in the straw (10) towards the stopper (12).
The straw includes a tube (11) extending between a first end (16) and a second end (17) and includes a gas-permeable but liquid-impermeable plug (12). The tube (11) is made of a thermochromic material that reversibly changes colour at a pre-set temperature threshold, by virtue of which colour change the tube (11) has a first visual appearance if the temperature thereof is below the preset threshold and a second visual appearance that is different from the first visual appearance if the temperature thereof is above the preset threshold.
A61D 19/02 - Instruments or methods for reproduction or fertilisation for artificial insemination
G01K 11/12 - Measuring temperature based on physical or chemical changes not covered by group , , , or using changes in colour, translucency or reflectance
B65D 65/40 - Applications of laminates for particular packaging purposes
B65D 75/30 - Articles or materials enclosed between two opposed sheets or blanks having their margins united, e.g. by pressure-sensitive adhesive, crimping, heat-sealing, or welding
56.
USE OF LA1-LIKE PEPTIDE ISOLATED FROM MAURUS PALMATUS VENOM AS AN ACTIVATOR OF SPERM MOTILITY IN MAMMALS
The invention relates to a La-1-like peptide agent that increases sperm motility. It is non-toxic and it may be used to treat male infertility in humans, and also to increase fertility in animals. It may be used in artificial reproductive techniques such as in vitro fertilisation (IVF), including intra-cytoplasmic sperm injection (ICSI). The La-1-like peptide agent may also be used in artificial insemination techniques such as intra-cytoplasmic uterine injection (IUI).
A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
A61K 35/646 - Arachnids, e.g. spiders, scorpions, ticks or mites
C07K 14/435 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
A61P 15/08 - Drugs for genital or sexual disordersContraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
57.
Apparatus for vaginal penetration of animals comprising a viewing system, in particular for locating the cervix of the uterus
An appliance for vaginal penetration includes a grip, the appliance being designed to receive a working tool, especially an insemination gun that passes through the grip. A guiding tube extends the grip in order to form a compact assembly, the guiding tube being designed so as to receive the front tip of the working tool therein and receiving a video viewing device such as an endoscopy-type tube including a lighting element on the front end thereof, the appliance for vaginal penetration including an electronic cell receiving the video images, provided with a device for transmitting images to a remote screen.
A61D 19/02 - Instruments or methods for reproduction or fertilisation for artificial insemination
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
A61M 31/00 - Devices for introducing or retaining media, e.g. remedies, in cavities of the body
A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
A61B 1/04 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor combined with photographic or television appliances
A61B 1/018 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor characterised by internal passages or accessories therefor for receiving instruments
A61B 1/12 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor with cooling or rinsing arrangements
A61B 1/303 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor for the vagina, i.e. vaginoscopes
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
A61B 90/30 - Devices for illuminating a surgical field, the devices having an interrelation with other surgical devices or with a surgical procedure
58.
DEVICE FOR PRESERVING A PREDETERMINED DOSE OF LIQUID-BASED SUBSTANCE, AND RANGE OF SUCH DEVICES
A device for preserving a predetermined dose of liquid-based substance, notably animal semen or a preservation medium containing embryos or tissue samples, comprises a tube (11) made of a weldable plastics material. The tube allows a service state in which a receiving portion (21) intended to contain the said predetermined dose has a circular cross-section whereas a sealing portion (22) comprises a welded pinch (19) and a transition zone (23). Over at least part of the sealing portion a differentiating edge region (28) gives the external surface of the tube a visual appearance different from the visual appearance of the external surface of the tube outside of the differentiating edge region. A range comprises such a device and a similar device but without the differentiating edge region.
The system comprises a straw and a liquid dilution medium. The straw comprises a tube (11) extending between a first end and a second end and comprises a gas-permeable, liquid-tight plug, said plug being arranged in the tube (11) in the vicinity of the first end of same and extending between a first end turned towards the first end of the tube (11) and a second end turned towards the second end of the tube (11). Said plug comprises an element (14) impregnated with a reagent (22) at least in the vicinity of a first end turned towards the second end of the tube (11). The liquid medium is provided to produce, by mixing, in predefined conditions, the liquid substance (21). The reagent (22) and the medium(27) are configured such that, when the substance (21) comes into contact with the first end of the impregnated element (14), it forms a hydrogel.
The invention relates to a feeding and positioning device (5) for straws (2) for packing animal semen on a support (4), with a feeding hopper (20) having an inner space (21) which receives the straws and is partially delimited by an inclined and electrically conductive bottom wall (38), an evacuation chute (22) with an inlet orifice, which opens into said inner space, and with an outlet orifice opposite said support, a disentangling system (25) having an electrically conductive and movable part configured to come into contact with said straws and to set them in motion in said inner space, an electrically conductive support, and a mechanical connection interface of said movable part on said support, and electrical connection elements which are directly connected, respectively, to said bottom wall and said support and to said movable part and said support.
The invention relates to a storage receptacle (1) with a longitudinal opening (5) through which straws (2) for packing liquid-based substance are passed in a predetermined orientation of the straws, a housing (3) provided for the straws and configured to be inserted slidably in a cover (4) of the receptacle, the latter having an open configuration, in which the housing is partially inserted in the cover and the opening is free for the passage of the straws, and a closure configuration, in which the housing is inserted in the cover and the opening is closed by the cover in order to prohibit the passage of the straws. The housing has a parallelepipedal shape, a first front wall in which the opening is formed, a first bottom wall, two first longitudinal walls extending parallel to the opening, and two first side walls which each have two diagonals of a length less than or equal to the length of the straws.
The invention relates to a device for storing straws for packing animal semen, configured to form part of a treatment installation provided with a machine (3) for treating said straws, said device (4) being configured to be arranged at the output of said machine where said straws are ejected in a predetermined orientation; said device having a receptacle (30) with an opening (31) which receives said straws and extends at least in a longitudinal direction corresponding to said predetermined orientation of said straws for their reception, and a movement system (32) configured to drive said receptacle, transversely with respect to said longitudinal direction of said opening, in a reciprocating movement between a first position and a second position at a distance from said first position, said straws received in said receptacle being moved relative to each other in order to be disposed in an organized state in said receptacle.
The invention relates to a straw comprising a tube (11) extending between a first end (13) and a second end (14) and comprising a stopper (12) placed in the tube near the first end thereof and extending between a first end (17) facing the first end of the tube, and a second end (20) facing the second end of the tube, said stopper and said tube being configured such that, after a liquid substance (22) has come in contact with the stopper via the second end thereof, the stopper blocks the passage of the liquid substance therethrough and is, by pushing on the first end thereof, slidable into the tube toward the second end thereof. Moreover, the stopper comprises, on the side of the second end of the tube, a barrier pad (16) consisting of hydrophobic threads over the entire cross-section of the tube.
The present invention relates to a composition for use in low dose artificial insemination and to a process for artificial insemination of a female mammal using a dose of sperm originating from a male mammal of the same species that is significantly lower than necessary in the absence of the composition. The preferred female mammal is a sow (sus scrofa), and preferably the composition is for use in artificial uterine insemination, and the process for artificial insemination preferably is uterine insemination.
The straw (11) filling device comprises a casing body having a cavity (43) in which the needle (9) of a nozzle (7) is placed. The needle is inserted into the straw tube (12) received in the cavity. The casing body is attached to a carriage separately from the needle. The cavity comprises a distal opening located on the distal end side of the needle, a proximal opening located on the proximal end side of the needle, and a longitudinal opening extending from the distal opening to the proximal opening, thus enabling placement and removal of the needle in and out of the cavity in a direction transverse to the direction of the needle and preventing an adult finger accessing the distal end of the needle. The machine comprises a device of this type and a conveyor (2) designed to keep the straw tube in a filling position during each cycle.
The straw comprises a tube (11) and a stopper (12) fixed facing the tube (11) and comprising a male connection end piece (29) configured so that a syringe needle (44) having a female connection end piece (45) with a standardized frustoconical internal surface can be coupled to said stopper (12) via engagement of the female connection end piece (45) of the needle on the male connection end piece (29) of the stopper (12). The injection device comprises such a straw (10) and a syringe needle (44). The method for emptying the straw involves the step of driving the dose of liquid-based substance (21) contained in the straw (10) toward the stopper (12).
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Biological media, particularly for preserving fresh or
frozen semen and/or for embryo collection and transfer;
filtering media for medical and/or veterinary use; liquid
media for collecting, preserving, freezing or thawing of
embryos or microorganisms of the animal kingdom; aqueous
vehicles for micro-organisms of the animal kingdom for
keeping them alive outside their natural environment; media
for washing, filtration and/or freezing of sperm, as well as
for the collection of oocytes. Tubes called straws for cryogenic preservation of biological
samples; straws for veterinary use; identification sheaths
and cases for the aforesaid straws; seminal fluid collection
apparatus.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Biological media, particularly for preserving fresh or
frozen semen and/or for embryo collection and transfer;
filtering media for medical and/or veterinary use; liquid
media for collecting, preserving, freezing or thawing of
embryos or microorganisms of the animal kingdom; aqueous
vehicles for micro-organisms of the animal kingdom for
keeping them alive outside their natural environment; media
for washing, filtration and/or freezing of sperm, as well as
for the collection of oocytes. Tubes called straws for cryogenic preservation of biological
samples; straws for veterinary use; identification sheaths
and cases for the aforesaid straws; seminal fluid collection
apparatus.
70.
STRAW FOR PRESERVING A PRESET DOSE OF A LIQUID-BASED SUBSTANCE
The straw includes a tube (11) extending between a first end (16) and a second end (17) and includes a gas-permeable but liquid-impermeable plug (12). The tube (11) is made of a thermochromic material that reversibly changes colour at a preset temperature threshold, by virtue of which colour change the tube (11) has a first visual appearance if the temperature thereof is below said preset threshold and a second visual appearance that is different from the first visual appearance if the temperature thereof is above said preset threshold.
A61D 19/02 - Instruments or methods for reproduction or fertilisation for artificial insemination
G01K 11/12 - Measuring temperature based on physical or chemical changes not covered by group , , , or using changes in colour, translucency or reflectance
71.
Straw for the preservation of a predetermined dose of liquid-based substance, in particular pure or diluted animal semen; and set comprising it
The container straw comprises a tube (11) and a stopper (12) that is permeable to gasses and impermeable to liquids, which stopper (12) is arranged in the tube (11) near one end (16), characterized in that it comprises an indicator component (20) configured to emit, at least when the container straw (10) is full, light the spectrum of which contains at least one spike having a peak of predetermined wavelength. The assembly comprises the container straw (10) and a container straw recognition device (26).
A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
A61D 19/02 - Instruments or methods for reproduction or fertilisation for artificial insemination
The bag comprises two flexible sheets (11) attached to each other by a weld area delimiting a pouch having a predefined volume when said bag is filled, said pouch being designed to contain a dose (27) of said diluted animal semen having said predefined volume. The surface (30) of each of said flexible sheets (11) faces said pouch (14) which is part of a layer (35) of weldable thermoplastic material. For one or preferably for each of said sheets (11), said layer of weldable thermoplastic material (35) comprises triclosan; and the ratio between said predefined volume of said pouch and the sum of the areas of the surfaces (30) of said sheets (11) facing said pouch is between 0.3 ml/cm2 and 0.5 ml/cm2 . The system comprises such bags and an antibiotic-free dilution medium.
The bag comprises two flexible sheets (11) attached to each other by a weld area delimiting a pouch having a predefined volume when said bag is filled, said pouch being designed to contain a dose (27) of said diluted animal semen having said predefined volume. The surface (30) of each of said flexible sheets (11) faces said pouch (14) which is part of a layer (35) of weldable thermoplastic material. For one or preferably for each of said sheets (11), said layer of weldable thermoplastic material (35) comprises triclosan; and the ratio between said predefined volume of said pouch and the sum of the areas of the surfaces (30) of said sheets (11) facing said pouch is between 0.3 ml/cm2 and 0.5 ml/cm2 . The system comprises such bags and an antibiotic-free dilution medium.
The invention relates to an appliance for vaginal penetration, comprising a grip (2), said appliance being designed to receive a working tool, especially an insemination gun (4) that passes through the grip, characterised in that it comprises a guiding tube (8) extending the grip (2) in order to form a compact assembly, said guiding tube being designed so as to receive the front tip of the working tool (12) therein and receiving a video viewing means such as an endoscopy-type tube (14) comprising a lighting element on the front end thereof, the appliance for vaginal penetration comprising an electronic cell receiving the video images, provided with means for transmitting images to a remote screen.
A61D 19/02 - Instruments or methods for reproduction or fertilisation for artificial insemination
A61B 19/00 - Instruments, implements or accessories for surgery or diagnosis not covered by any of the groups A61B 1/00-A61B 18/00, e.g. for stereotaxis, sterile operation, luxation treatment, wound edge protectors(protective face masks A41D 13/11; surgeons' or patients' gowns or dresses A41D 13/12; devices for carrying-off, for treatment of, or for carrying-over, body liquids A61M 1/00)
37 - Construction and mining; installation and repair services
Goods & Services
Veterinary apparatus and instruments, namely machines for
filling and sealing straws for artificial insemination. Installation, maintenance and repair of machines for filling
and sealing straws for artificial insemination.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Biological media, particularly for preserving fresh or
frozen semen and/or for embryo collection and transfer;
filtering media for medical and/or veterinary use; liquid
media for collecting, preserving, freezing or thawing of
embryos or microorganisms of the animal kingdom; aqueous
vehicles for micro-organisms of the animal kingdom for
keeping them alive outside their natural environment; media
for washing, filtration and/or freezing of sperm, as well as
for the collection of oocytes. Sachet/bag for packaging of diluted animal semen suitable
for artificial insemination, particularly of porcine
species.
37 - Construction and mining; installation and repair services
Goods & Services
Veterinary apparatus and instruments, namely machines for
filling and sealing straws for artificial insemination. Installation, maintenance and repair of machines for filling
and sealing straws for artificial insemination.
80.
ARTIFICIAL INSEMINATION PROBE FOR A LIVESTOCK ANIMAL SUCH AS A PIG
The probe comprises an elongate body and a tip disposed at one end of the elongate body, the tip being configured to be positioned in the cervix of the animal, and extending between a proximal end (14) located at the elongate body side and a distal end located at the side opposite the elongate body, with, between the proximal end (14) and the distal end, a set of lateral flanges extending outwards from a central shaft; characterised in that the flange (18) closest to the proximal end (14) has, at the base of same, an annular bulge (35) configured such that said flange (18) has a sudden change of thickness at the junction between the annular bulge (35) and the peripheral portion of same located further outside than the annular bulge (35).
The probe comprises an elongate body and a tip disposed at one end of the elongate body, the tip being configured to be positioned in the cervix of the animal, and extending between a proximal end (14) located at the elongate body side and a distal end located at the side opposite the elongate body, with, between the proximal end (14) and the distal end, a set of lateral flanges extending outwards from a central shaft; characterised in that the flange (18) closest to the proximal end (14) has, at the base of same, an annular bulge (35) configured such that said flange (18) has a sudden change of thickness at the junction between the annular bulge (35) and the peripheral portion of same located further outside than the annular bulge (35).
37 - Construction and mining; installation and repair services
Goods & Services
Veterinary apparatus and instruments, namely, machines for filling and sealing straws for artificial insemination Installation, maintenance and repair of machines for filling and sealing straws for artificial insemination
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
[ Biological preparations for veterinary purposes for preserving fresh or frozen semen and/or for embryo collection and transfer; chemical reagents for medical and/or veterinary use; chemical reagents for medical or veterinary purposes for collecting, preserving, freezing or thawing of embryos or microorganisms of the animal kingdom; chemical reagents for medical or veterinary purposes for micro-organisms of the animal kingdom for keeping them alive outside their natural environment; chemical reagents for medical or veterinary purposes for washing, filtration and/or freezing of sperm, as well as for the collection of oocytes ] Sachet/bag for packaging of diluted animal semen suitable for artificial insemination, particularly of porcine species
37 - Construction and mining; installation and repair services
Goods & Services
Veterinary apparatus and instruments, namely, machines for filling and sealing straws for artificial insemination [ Installation, maintenance and repair of machines for filling and sealing straws for artificial insemination ]
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
[ Biological media, particularly for preserving fresh or frozen semen and for embryo collection and transfer; filtering media in the nature of chemical reagents for medical or veterinary use; liquid media in the nature of sperm freezing medium and in vitro fertilization medium for collecting, preserving, freezing or thawing of embryos or microorganisms of the animal kingdom; aqueous vehicles in the nature of veterinary chemical reagents for micro-organisms of the animal kingdom for keeping them alive outside their natural environment; Cryopreservation media comprised of biological preparations for washing, filtration and freezing of sperm, as well as for the collection of oocytes ] Tubes called straws for cryogenic preservation of biological samples; straws in the nature of medical sample tubes for veterinary use; specially adapted cases and sheaths for medical instruments, namely, identification sheaths and cases for the aforesaid straws; seminal fluid collection apparatus
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
[ Biological preparations for veterinary purposes for preserving fresh or frozen semen and/or for embryo collection and transfer; chemical reagents for veterinary use; chemical reagents for veterinary purposes for collecting, preserving, freezing or thawing of embryos or microorganisms of the animal kingdom; chemical reagents for veterinary purposes for micro-organisms of the animal kingdom for keeping them alive outside their natural environment; chemical reagents for veterinary purposes for washing, filtration and/or freezing of sperm, as well as for the collection of oocytes ] Tubes called straws for cryogenic preservation of medical biological samples; straws in the nature of medical sample tubes for veterinary use; specially adapted cases and sheaths for medical instruments, namely, identification sheaths and cases for the aforesaid straws; medical devices for obtaining body fluid samples, namely, seminal fluid collection apparatus
87.
STRAW FOR PRESERVING A PREDEFINED DOSE OF A LIQUID SUBSTANCE, IN PARTICULAR DILUTED ANIMAL SEMEN; AND SYSTEM COMPRISING SUCH A STRAW AND A DILUTION MEDIUM FOR PRODUCING SUCH A SUBSTANCE
The straw comprises a tube (11) extending between a first end and a second end and comprises a gas-permeable, liquid-tight plug, said plug being arranged in the tube (11) in the vicinity of the first end of same and extending between a first end turned towards the first end of the tube (11) and a second end turned towards the second end of the tube (11). Said plug comprises an element (14) impregnated with multivalent cations (22) at least in the vicinity of a first end turned towards the second end of the tube (11). The system comprises the straw and a liquid medium provided to produce, by mixing, in predefined conditions, the liquid substance (21). The medium contains an alginate (23) in solution.
The system comprises a straw and a liquid dilution medium. The straw comprises a tube (11) extending between a first end and a second end and comprises a gas-permeable, liquid-tight plug, said plug being arranged in the tube (11) in the vicinity of the first end of same and extending between a first end turned towards the first end of the tube (11) and a second end turned towards the second end of the tube (11). Said plug comprises an element (14) impregnated with a reagent (22) at least in the vicinity of a first end turned towards the second end of the tube (11). The liquid medium is provided to produce, by mixing, in predefined conditions, the liquid substance (21). The reagent (22) and the medium(27) are configured such that, when the substance (21) comes into contact with the first end of the impregnated element (14), it forms a hydrogel.
The sheath (30) comprises a tube (31) and an end piece (32) that comprises a foot (33) introduced into an end portion of the tube (31), and a head (34) arranged in the extension of the tube (31). The foot (33) comprises, on the outer surface (40) thereof, a plurality of annular ribs (41-44) facing the inner surface (45) of the tube (31). The head (34) comprises a shoulder (38) facing the section (39) of the tube (31), projecting over the root of the foot (33). The end piece (32) and the tube (31) are attached to the periphery of at least one of said annular ribs exclusively by intrinsic welding. The method comprises the step of carrying out a peripheral tightening of the outer surface (37) of the tube on a level with the ribs (41-44), and the step of applying a sonotrode to the outer surface (35-36) of the head (34).
The invention concerns a system for collecting animal semen, comprising a container (3) configured to be mounted on an end (9) of an artificial vagina (2), having an internal space (15) configured to receive said semen and configured to comprise a first dilution extender (5) before receiving said semen, and said system (1) comprises a collecting device (4) configured to be at least partially inserted into said container and to be fastened to said vagina, and being interposed between said vagina and said container, said collecting device comprising a flow channel (23) for said semen extending within said internal space of said container and a discharge aperture (26) for said semen open to said internal space; and said system is configured to prevent, at least for the most part, said first dilution extender from passing in said flow channel of said collecting device.
The straw comprises a tube (11) having a swelling plug (15) provided with a fibrous support agent and a swelling agent combined with the support agent and configured, at least close to a second end (18) of the swelling plug, after a liquid-based substance has come up against its second end, to be in a state of swelling constrained by said tube such that if a first part (26) of the swelling plug of length comprised between 2 mm and 3 mm starting from its second end has come out of the tube via a second end (14) of the tube, whereas a second part of the swelling plug remains in the tube, the first part of the swelling plug becomes decompacted and expands with the second end of the swelling plug which assumes a diameter (d) at least equal to one and a half times the inner diameter of the tube.
The invention relates to a straw comprising a tube (11) extending between a first end (13) and a second end (14) and comprising a stopper (12) placed in the tube near the first end thereof and extending between a first end (17) facing the first end of the tube, and a second end (20) facing the second end of the tube, said stopper and said tube being configured such that, after a liquid substance (22) has come in contact with the stopper via the second end thereof, the stopper blocks the passage of the liquid substance therethrough and is, by pushing on the first end thereof, slidable into the tube toward the second end thereof. Moreover, the stopper comprises, on the side of the second end of the tube, a barrier pad (16) consisting of hydrophobic threads over the entire cross-section of the tube.
The straw comprises a tube (11) having a swelling pad (15) provided with a fibrous carrier and a swelling agent associated with the support agent and configured to be at least in the vicinity of one second end (18) of the swelling pad, after a liquid-based substance has encountered its second end, in a swelling state thwarted by said tube such as if a first portion (26) of the swelling pad of length between 2 mm and 3 mm from its second end is exited from the tube by a second end (14) of the tube, while a second part of the swelling pad remains in the tube, the first part of the swelling pad is decompressed and blossoms with the second end of the swelling pad which takes a diameter (d) at least equal to one and a half times the inner diameter of the tube.
The invention relates to a straw comprising a tube (11) and a gas-permeable and liquid-tight stopper (12), said stopper (12) being arranged in the tube (11), close to an end (16). The invention is characterised in that the stopper (12) comprises an indicator component (20) having a first pre-determined colour in the absence of previous contact with said substance (21) and a second pre-determined colour, of a different shade from that of the first colour, once it has been in contact with said substance (21). The assembly comprises the straw (10) and a device (26) for controlling the filling of the straw.
The container straw comprises a tube (11) and a stopper (12) that is permeable to gasses and impermeable to liquids, which stopper (12) is arranged in the tube (11) near one end (16), characterized in that it comprises an indicator component (20) configured to emit, at least when the container straw (10) is full, light the spectrum of which contains at least one spike having a peak of predetermined wavelength. The assembly comprises the container straw (10) and a container straw recognition device (26).
The invention relates to a straw comprising a tube (11) and a gas-permeable and liquid-tight stopper (12), said stopper (12) being arranged in the tube (11), close to an end (16). The invention is characterised in that the stopper (12) comprises an indicator component (20) having a first pre-determined colour in the absence of previous contact with said substance (21) and a second pre-determined colour, of a different shade from that of the first colour, once it has been in contact with said substance (21). The assembly comprises the straw (10) and a device (26) for controlling the filling of the straw.
The straw comprises a tube (11) and a cap (12) permeable to gases and liquid-tight, said cap (12) being arranged in the tube (11) in the vicinity of one end. The cap (12) comprises a magnetic component configured such that a magnet (21), placed flush with the tube (11) at a right angle to the cap (12), and then moved on a horizontal surface (20), is then followed by the straw (10).
The sheath (30) comprises a tube (31) and an end piece (32) that comprises a foot (33) introduced into an end portion of the tube (31), and a head (34) arranged in the extension of the tube (31). The foot (33) comprises, on the outer surface (40) thereof, a plurality of annular ribs (41-44) facing the inner surface (45) of the tube (31). The head (34) comprises a shoulder (38) facing the section (39) of the tube (31), projecting over the root of the foot (33). The end piece (32) and the tube (31) are attached to the periphery of at least one of said annular ribs exclusively by intrinsic welding. The method comprises the step of carrying out a peripheral tightening of the outer surface (37) of the tube on a level with the ribs (41 -44), and the step of applying a sonotrode to the outer surface (35-36) of the head (34).
The invention relates to a machine for sealing tubes made of a weldable plastic material, comprising at least one mobile jaw (31) having a heating projecting member (41, 42) suitable for forming a flat sealing area aligned with said heating projecting member (41, 42) by crushing and welding such a tube (10). The mobile jaw (31) comprises: a first metal plate (37) supporting said heating projecting member (41, 42), a Peltier element (35) in thermal contact with the first metal plate (37), and a second metal plate (36) in thermal contact with said Peltier element (35). The machine (30) also comprises a control unit connected to said Peltier element (35) for supplying the latter with electric power, by means of which said heating projecting element (41, 42) is heated or cooled by said Peltier element (35).
The invention relates to a machine for sealing tubes made of a weldable plastic material, comprising at least one mobile jaw (31) having a heating projecting member suitable for forming a flat sealing area aligned with said heating projecting member by crushing and welding such a tube; said machine being characterised in that said mobile jaw (31) comprises two such separate projecting heating members, respectively a first heating projecting member (41) that is elongate in a first predetermined direction, suitable for forming such a flat sealing area (19) on a tube (10) lying a horizontal position, and a second heating projecting member (42) elongate in a second predetermined direction that is transverse to said first direction, suitable for forming such a flat sealing area on a vertical tube.
B29C 65/24 - Joining of preformed partsApparatus therefor by heating, with or without pressure using heated tool characterised by the means for heating the tool
