Present disclosure generally relates to devices and methods for conveying small amounts of fluids, and particularly relates to apparatus and method for scalable fluid delivery to achieve minimal motion of syringe plunger using multiple kinematic chain elements/pathways actuated by a single Motion Actuating Device (MAD). The scalable fluid delivery apparatus provides first kinematic pathway corresponding to high linear resolution mode of Piston Drive Member (PDM) and second kinematic pathway corresponding to low linear resolution mode of PDM. The first kinematic pathway includes final step of delivering fluid comprised in syringe, upon pushing plunger, and second kinematic pathway includes final step of performing forward motion or reverse motion of PDM. Forward motion, or reverse motion of PDM is for priming barrel and removable fluid delivery tube or to revert the PDM to an initial position, respectively, or to deliver the fluid.
Disclosed herein a method, tin Electrical Stimulation System (ESS) 101, and an electronic wearable unit 301 for controlling an electrical stimulation 113 to a pelvic region of a subject 103. The electronic wearable unit 301 comprises a non-skin contacting outer surface 307, a skin contacting inner surface 305 with a crotch part for removably attaching a urine collecting device 309, and the ESS 101 removably placed within a space bounded by the outer surface 307 and the inner surface 305. An input 105 for initiating a session is received. Further, at least one of, an activity level 107 of muscles in and around the pelvic region, an orientation 109 of one or more of the muscles, and a body posture 111 of the subject 103 is received, throughout the session. Based on the determination, the electrical stimulation 113 to the pelvic region of the subject 103 is controlled. Thus, the present disclosure enables portable administration of treatment, and further enables extending the electrical stimulation 113 from portable use in a fixed, body posture to ambulatory use, in multiple body postures.
A nodule comprising a first support 110 and a second support 120, the first support 110 placed at a pre-determined distance 115 from the second support 120, wherein an inner side 114 of the first support 110 facing the inner side 124 of the second support, such that the first support 110 is aligned parallel to the second support 120; a first end 132 of an arch 130 coupled to the first support 110 and a second end 134 of the arch 130 coupled to the second support 120, wherein the arch 130 projects above the first support 110 and the second support 120; and a flat resting platform 140 mounted on top of the arch 130, and a plurality of nodules 100A affixed at a per-determined location and pre-determined orientation on a base forming an insole.
There is provided markers, systems, and methods for creating and utilizing a marker containing identification information. The embodiments include an identifying marker comprised of high temperature material for tracking a component in a high temperature environment. The marker may be disposed on the component such that the marker is subject to high temperatures while affixed to the component. The marker may provide the ability to track a history of the component the marker is attached to for maintenance.
G06K 19/06 - Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
5.
COMPACT TANDEM CYLINDER RECIPROCATING ENGINE FOR CO2 POWER GENERATION
The present disclosure relates to an engine (100) including a cylinder (102) that is filled with carbon dioxide. A first piston (104) is slidably configured inside the cylinder (102) and being configured to form a first cylinder (108) with a first end (130) of the cylinder (102). A second piston (106) is slidably configured inside the cylinder (102) and being configured to form a second cylinder (110) with a second end (132) of the cylinder (102). A heater (112) is circumferentially disposed around the first cylinder (108) and the first piston (104) is configured to expand a hot carbon dioxide received inside the first cylinder (108) from the heater (112). A cooler (116) is circumferentially disposed around the second cylinder (110) and second piston (104) is configured to compress a cold carbon dioxide received inside the second cylinder (110) from the cooler (116).
F01B 7/16 - Machines or engines with two or more pistons reciprocating within same cylinder or within essentially coaxial cylinders with pistons synchronously moving in tandem arrangement
F01B 31/08 - Cooling of steam engines; Heating; Heat insulation
F01K 25/10 - Plants or engines characterised by use of special working fluids, not otherwise provided for; Plants operating in closed cycles and not otherwise provided for using special vapours the vapours being cold, e.g. ammonia, carbon dioxide, ether
6.
SYSTEM AND METHOD FOR GENERATING MOLTEN METAL DROPLETS FOR ADDITIVE MANUFACTURING
The present disclosure relates to a system for additive manufacturing. The system includes a frame, a CNC bed configured with the frame. A metal dispensing mechanism configured to eject metal droplets on the CNC bed. The metal dispensing mechanism is configured to controllably move with respect to the CNC bed for manufacturing the object. The metal dispensing mechanism includes a first nozzle, functionally configured with the CNC bed, for controllably dispensing the metal droplets on the CNC bed, and the nozzle is fluidically configured with a reservoir having the metal. A piston configured with the reservoir, and the piston is configured to push the molten metal from the reservoir such the molten metal is released from the reservoir towards the first nozzle. The piston is made of thermally insulating material, and a transducer configured with the piston to facilitate mechanical jerking of the piston for facilitating the pushing of the molten metal from the reservoir.
B22F 12/90 - Means for process control, e.g. cameras or sensors
B29C 64/118 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using filamentary material being melted, e.g. fused deposition modelling [FDM]
B33Y 30/00 - ADDITIVE MANUFACTURING, i.e. MANUFACTURING OF THREE-DIMENSIONAL [3D] OBJECTS BY ADDITIVE DEPOSITION, ADDITIVE AGGLOMERATION OR ADDITIVE LAYERING, e.g. BY 3D PRINTING, STEREOLITHOGRAPHY OR SELECTIVE LASER SINTERING - Details thereof or accessories therefor
B33Y 50/02 - Data acquisition or data processing for additive manufacturing for controlling or regulating additive manufacturing processes
7.
POLYPEPTIDE FRAGMENTS, IMMUNOGENIC COMPOSITION AGAINST SARS-CoV-2, AND IMPLEMENTATIONS THEREOF
The present disclosure discloses the polypeptide fragment having an amino acid sequence with at least 95% identity to the amino acid sequence selected from the group consisting of SEQ ID NO: 2, SEQ ID NO: 4, and SEQ ID NO: 6. The present disclosure also discloses nucleic acid fragment encoding the polypeptide fragment as described herein. Moreover, the present disclosure also discloses recombinant construct, recombinant vector and recombinant host cells. Also disclosed herein is an immunogenic composition comprising the polypeptide fragment as described herein, and a method for preparing the said immunogenic composition. The immunogenic composition is in form of vaccine. The polypeptide fragment and/or immunogenic composition is capable of eliciting protection against severe acute respiratory syndrome coronavirus 2. A kit comprising the polypeptide, or the immunogenic composition as described herein is also disclosed.
The present disclosure relates to a polypeptide fragment comprising a polypeptide of S2 ectodomain fragment of spike protein of Coronavirus linked to a polypeptide of receptor binding domain (RBD) fragment of spike protein of Coronavirus, at C- terminal or N-terminal end of the S2 ectodomain fragment. The present disclosure also provides a DNA construct comprising a polynucleotide encoding the disclosed polypeptide fragment. The present disclosure further provides an immunogenic composition comprising the polypeptide fragment and a method of preparing the immunogenic composition. Furthermore, the present disclosure provides a method of eliciting an immune response in a subject by administering the immunogenic composition.
The present application discloses a Full Duplex Microstrip Patch Antenna design with improved scalability and performance. The antenna integrates a transmitter and receiver on opposite vertical edges of a metallic plate, employing strategically positioned metallic vias for signal optimization. The antenna also includes diametrically placed L-shaped stubs and parallel metallic lines, which contribute to increased operational bandwidth. The present disclosure discloses a versatile and scalable solution, addressing challenges in contemporary communication systems.
JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (India)
Inventor
Nongthomba, Upendra
Pakkiriswamy, Thilagar
Chelliah, James Premdoss Clement
Pradhan, Sambit
Mishra, Shefali
Abstract
The present disclosure provides a method for the treatment of epilepsy syndrome and/or seizure in a subject, by administering a therapeutically effective amount of the compound or salt thereof as disclosed herein. Embodiments herein further overcome the challenges that are generally observed with the use of existing anti- epileptic drugs, such as poor patient response, severe physical and/or psychological side effects and prevalence of drug resistance, etc. Accordingly, the present disclosure provides a compound for use in treating epilepsy syndrome and/or seizure. Also disclosed herein is a composition for the treatment of epilepsy syndrome and/or seizure.
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 31/366 - Lactones having six-membered rings, e.g. delta-lactones
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
The present subject matter is related to a hybrid additive manufacturing technique or a methodology where an amalgamation of layered and non-layered 3D print is designed and used for printing multi-oriented and multi-fiber deposition in a 3D space with customized patterns or specific patterns designed.
B29C 64/165 - Processes of additive manufacturing using a combination of solid and fluid materials, e.g. a powder selectively bound by a liquid binder, catalyst, inhibitor or energy absorber
B33Y 70/00 - Materials specially adapted for additive manufacturing
12.
A SYSTEM AND A METHOD FOR GENERATING MECHANICAL POWER USING SUPER CRITICAL CARBON DIOXIDE
A system for generating mechanical power using super critical carbon dioxide (sCO2) is disclosed. The system includes at least one expansion cylinder (5) housing a first piston (5a) and at least one compression cylinder (6) housing a second piston (6a). A first heat exchanger (C) is fluidically connected to the compression cylinder (6) and the expansion cylinder (5), and a second heat exchanger (H) is fluidically connected to the compression cylinder (6) and the expansion cylinder (5). The first heat exchanger (C) cools the CO2 received from the expansion cylinder (5), and the compression cylinder (6) pressurizes the CO2 cooled by the first heat exchanger (C). The second heat exchanger (H) heats the CO2 from the compression cylinder (6) and supplies to the expansion cylinder (5). The high temperature and high-pressure CO2 drives the first piston (5a) housed inside the expansion cylinder (5) to generate mechanical energy.
F01K 25/10 - Plants or engines characterised by use of special working fluids, not otherwise provided for; Plants operating in closed cycles and not otherwise provided for using special vapours the vapours being cold, e.g. ammonia, carbon dioxide, ether
F01K 7/32 - Steam engine plants characterised by the use of specific types of engine; Plants or engines characterised by their use of special steam systems, cycles or processes; Control means specially adapted for such systems, cycles or processes; Use of withdrawn or exhaust steam for feed-water heating the engines using steam of critical or over-critical pressure
13.
SYSTEM AND METHOD FOR VARIABLE REPETITION RATE SHOT-TO-SHOT RAPID SCAN PUMP-PROBE AND 2D ELECTRONIC SPECTROSCOPY
Embodiments of this disclosure is related to a system and a method that provides with a time- resolved pump- probe spectrometer which resolves the sample spectral information across a >100 nm visible spectral bandwidth with sub-200 fs time resolution with scatter robust high sensitivity, while working at the highest possible throughput limited only by the camera speed for any laser repetition rate. The spectrometer throughput is electronically controllable to work for any laser repetition rates in the range of <1 kHz to a higher range that is limited only by the camera readout rate. The camera electronics, pump beam modulation and the stage encoder may all be synchronized to the laser repetition rate such that the pump-probe delay can be scanned continuously (rapid scan) instead of stepwise.
The present disclosure discloses a method (200) of manufacturing an energy exchanging device (100). The method includes defining a plurality of through slots (14, 17) in a plurality of plates (2) by a through cut machining process, in which, each of the plurality of through slots define a flow channel. The method further includes stacking the plurality of plates (2) with at least one blanking member (24) positioned therebetween. Such stacking of the plurality of plates (2) forms a plurality of fluid flow paths about the plurality of through slots. The method further includes bonding the at least one blanking member with the plurality of plates, to form an energy exchanging core (1). The method further includes defining at least two inlet ports (45a, 45b) and at least two outlet ports (46a, 46b) in the core, for flow of fluid along the plurality of fluid flow paths within the core.
F28D 9/00 - Heat-exchange apparatus having stationary plate-like or laminated conduit assemblies for both heat-exchange media, the media being in contact with different sides of a conduit wall
B23P 15/26 - Making specific metal objects by operations not covered by a single other subclass or a group in this subclass heat exchangers
15.
METAL MATRIX POLYMER DERIVED CERAMIC COMPOSITES, PROCESSES OF PRODUCTION AND USES THEREOF
The present disclosure is in the field of metal matrix polymer derived ceramic composites, processes of production and uses thereof. In particular, the disclosure concerns metal matrix polymer derived ceramic composites comprising ceramic nanoparticles, processes of production comprising a step of severe plastic deformation, and uses thereof.
C22C 1/053 - Making hard metals based on borides, carbides, nitrides, oxides or silicides; Preparation of the powder mixture used as the starting material therefor with in situ formation of hard compounds
Techniques for printing high viscosity fluids are described. In an example, a printer for printing high viscosity fluids is described. The printer includes a fluid dispensing mechanism to generate a droplet of a fluid. The printer further includes a mesh arranged beneath the fluid dispensing mechanism, where the droplet is to impact on the mesh upon generation. Further, the printer includes a substrate arranged beneath the mesh, where a distance between the mesh and the substrate is less than a predetermined value determined based on a viscosity of the fluid, and where the predetermined value indicates a maximum distance traversed by a fluid jet from amongst a plurality of fluid jets ejected from the mesh upon impact of the droplet on the mesh.
CHAIRMAN, DEFENCE RESEARCH & DEVELOPMENT ORGANISATION (India)
Inventor
K. P., Arunkumar
Murthy, Chandra R.
P., Muralikrishna
Abstract
The present disclosure relates to method and system (104) for generating signal (107) for wireless communication. The method comprises obtaining one or more pre-defined communication parameters of wireless communication channel (103), comprising at least lower cut-off frequency and upper cut-off frequency. Further, the method comprises determining bandwidth of each of plurality of subcarriers (106) of signal (107) for wireless communication, based on lower cut-off frequency, upper cut-off frequency, symbol bandwidth of one or more symbols of each of plurality of subcarriers (106), and number of plurality of subcarriers (106). Furthermore, the method comprises determining one or more parameters of each of plurality of subcarriers (106), based on the corresponding bandwidth and pre-determined maximum time-scaling factor associated with wireless communication channel (103). Thereafter, the method comprises generating the signal (107) comprising plurality of subcarriers (106), for wireless communication, based on one or more parameters of each of plurality of subcarriers (106).
Present disclosure discloses a system for separating hydrogen from feed gas. The system includes at least one compressor adapted to pressurize the feed gas to predefined pressure. One or more adsorber columns are fluidly coupled to the compressor and are adapted to receive the pressurized feed gas, where the adsorber columns include a body and an adsorber bed, which is disposed within the body. The adsorber bed is configured to separate hydrogen from the feed gas. Further, the one or more adsorber columns includes a plurality of channels defined in at least one of the adsorber bed and adjacently along a length of the adsorber bed, where the channels are configured to channelize the hydrogen and regulate temperature of the adsorber bed. The configuration of the system aids in extracting pure hydrogen at low feed gas pressure.
B01D 53/04 - Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by adsorption, e.g. preparative gas chromatography with stationary adsorbents
B01D 53/14 - Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by absorption
19.
A DIAGNOSTIC SYSTEM COMPRISING AN EDIBLE ELECTRONIC DEVICE
The present disclosure provides a diagnostic system (100) comprising an edible electronic device (101) and an external transceiver (201). The edible electronic device (101) relays a sinusoidal signal from a field coil (203) to a pick-up coil (204) of the external transceiver (201) when it is in proximity of the external transceiver (201). This sinusoidal signal is distorted by a sensor output from a sensor (104) of the edible electronic device (101 ). The degree of distortion is proportional to the sensor output which is proportional to the amount of the analyte sensed by the sensor (104). The degree of distortion is measured to determine an analyte value. All components of the edible electronic device (101) are built using edible materials. The edible electronic device (101) is therefore safely digested and eliminated by the patient. The edible electronic device is safe to use without an expert medical intervention.
The invention provides a method for homogenized coherent excitation of a sample for determining molecular structure. The method includes selecting a monochromatic coherent light, homogenizing the monochromatic coherent light; irradiating the sample with the homogenized monochromatic light; collecting the Raman scattered light to obtain a profile and analyzing the profile to obtain chemical specific signature of the sample. The invention also provides a method for obtaining two dimensional imaging of a sample using irradiation of large sample area by homogenized monochromatic light without compromise in spatial resolution. A system for homogenized coherent excitation of a sample for determining molecular structure is also provided.
The method includes homogenizing a monochromatic coherent light source, irradiating the sample at plurality of points along all planes with the homogenized monochromatic light, collecting the molecular scattered light from all angles and planes to obtain a plurality of profile, resolving the plurality of profiles to obtain a molecular intensity maps, and reconstituting the intensity maps to obtain a three dimensional image of the sample. The system described is capable of obtaining molecular specific 3D morphology and profile of samples. The system described is capable of differentiating different chemicals or sample distribution throughout the 3D volume.
A system and method for extracting mathematical formulae from the one or more technical documents is disclosed. The method includes identifying variables and a concept associated with each of the variables from the one or more technical documents. The method includes determining interdependencies between variables in the extracted mathematical formulae based on the identified variables and the concept associated with the variables. The method includes generating the knowledge base based on the determined interdependencies. The method further includes providing access to the knowledge base to an end-user.
The invention provides a method for rapid detection of the viability of microorganisms. The method includes capturing a first unique signature with respect to a first lipid component, capturing a second unique signature with respect to a second lipid component, transforming each of the first lipid signatures and second lipid signatures to obtain amplified signatures, comparing the amplified signatures to obtain a first ratio and repeating the abovementioned steps at least one more time to obtain a second ratio. The alteration in the first ratio and the second ratio provides the indication for cardiovascular disorder.
G01N 21/3577 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light for analysing liquids, e.g. polluted water
The present disclosure provides a trapping device for trapping microbes, the device comprises a porous polymeric structure with a proximal end and a distal end, wherein the proximal end and the distal end is optionally provided with a hole or core on the 5 longitudinal direction. The present disclosure also provides a process of preparing the device and implementations thereof.
C12Q 1/04 - Determining presence or kind of microorganism; Use of selective media for testing antibiotics or bacteriocides; Compositions containing a chemical indicator therefor
25.
OXY-STEAM BIOMASS GASIFICATON SYSTEM FOR GENERATING HYDROGEN RICH SYNGAS
Examples of a system (100, 200) and a method (300) for converting a biomass feedstock into a hydrogen rich syngas, are described. The system (100, 200) includes a gasification reactor (102) including an inlet (104) with a lock hopper, an outlet (106), and side walls (108) between the inlet (104) and the outlet (106). The system (100) may further include a plurality of injectors (110, 202) protruding inside the gasification reactor (102) up to a certain depth along the length of the gasification reactor (102). In another example, the plurality of injectors (110, 202) may also be inclined at an angle with respect to the side walls (108) of the gasification reactor (102). The system (100, 200) further comprises a plurality of thermocouples (112) for determining a temperature profile of the gasification reactor (102).
The invention provides a method of obtaining a biomarker for blood anomaly using Raman scattering. The method includes the first step of capturing at least two unique Raman signatures with respect to the biomarker. The Raman signatures are obtained at regular interval. Second step is comparing the obtained unique Raman signatures to detect the change in the signature. Change in the Raman signature provides the indication for blood anomaly.
An information processing apparatus includes one or more memories; and one or more processors coupled to the one or more memories, the one or more processors being configured to decide a gain matrix based on an input metric, perform selection of first training data from a plurality of unlabeled training data, to be used for training a machine learning model, based on the gain matrix, and perform training of the machine learning model based on the first training data, a predicted label that is predicted from the first training data, and a loss function including the gain matrix.
A portable system (100) for accelerated wound healing is disclosed. The portable system (100) includes a handheld device (102) having a primary piston (104) located at a proximal end (302) and a secondary piston (106) located at a distal end (304). The primary piston (104) moves towards the distal end (304) to collide with the secondary piston (106) on receiving a pressure from the proximal end (302). A cartridge (108), including a column (110) filled with liquid, is located in physical contact with the secondary piston (106). Collision of the primary and the secondary pistons initiates a shockwave, in the liquid, that traverses through the column (110) to a membrane (112) located at a bottom end (306) of the column (110). The membrane (112) transfers energy of the shockwave to a wound area for accelerated healing of a wound.
A61B 17/225 - Surgical instruments, devices or methods, e.g. tourniquets for extracorporeal shock wave lithotripsy [ESWL], e.g. by using ultrasonic waves
Examples of a reusable drug delivery device (100, 200) and a method (400) of using the reusable drug delivery device (100, 200) for delivering a drug to a patient are described. The reusable drug delivery device (100, 200) may include a hollow top casing (102) including a first end (106) with a safety and a second end (108). The hollo top casing (102) encloses an injection mechanism slider (202), an injection mechanism holder (208), an injection spring (220), and a button spring (228). The reusable drug delivery device (100, 200) may further include a hollow bottom casing (104) which encloses a retraction mechanism holder (222), a needle retraction spring (224), and a needle retractor (226). The reusable drug delivery device (100, 200) further includes a syringe unit (214) comprising a syringe (216) and a syringe holder (218).
Disclosed herein is method and a navigation system for dynamically controlling navigation of an autonomous vehicle. In an embodiment, method comprises determining a trajectory path, comprising a plurality of path segments including at least one curved path segment and a straight path segment, by adjusting a plurality of waypoints in a base route of the autonomous vehicle and joining the plurality of waypoints using a predefined path planning model. Thereafter, a velocity profile distribution is generated for the autonomous vehicle by determining a start terminal velocity, an end terminal velocity and acceleration of the autonomous vehicle through each of the plurality of path segments in the trajectory path. Finally, a dynamic motion command is determined and applied to the autonomous vehicle based on the velocity profile distribution for dynamically controlling the navigation of the autonomous vehicle.
This disclosure relates to methods of promoting immune responses against HIV and compositions related thereto. In certain embodiments, this disclosure relates to methods of vaccinating for HIV comprising administering to the subject a priming composition followed by a boosting composition. In certain embodiments, the priming composition comprises a recombinant virus such as recombinant MVA that encodes an Env protein of HIV or segment thereof. In certain embodiments, the boosting composition comprises a trimeric cyclically permuted gp120 chimeric protein reported herein or DNA encoding the same.
The present disclosure provides a compound of Formula I, its stereoisomers, intermediates, and pharmaceutically acceptable salts thereof, capable of inhibiting DNA Ligase IV enzyme activity and nonhomologous end joining (NHEJ). The present disclosure also provides a process for preparing the compounds of Formula I and methods thereof.
A61K 31/495 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
33.
CRISPR-DCAS13 SYSTEM, COMPOSITION, AND METHOD TO INDUCE TRANSLATIONAL READTHROUGH ACROSS STOP CODONS
The present disclosure discloses a recombinant expression vector comprising a guide polynucleotide complementary to a target sequence, operably linked to a promoter, wherein the target sequence has a nucleotide sequence selected from the group consisting of SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 8, and SEQ ID NO: 9, and wherein the guide polynucleotide has contiguous nucleotides complementary to the target sequence in the range of 24-30 nucleotides, and wherein the guide polynucleotide is complementary to a region within at least 50 nucleotides downstream of a canonical stop codon or pre-mature stop codon of the target sequence; and a polynucleotide encoding dCasl3 protein having a nucleotide sequence selected from SEQ ID NO: 5, or SEQ ID NO: 31, operably linked to a promoter. A method and a composition for inducing the translational readthrough is also disclosed.
C12N 15/00 - Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
C12N 15/67 - General methods for enhancing the expression
C12P 19/34 - Polynucleotides, e.g. nucleic acids, oligoribonucleotides
A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
A compact energy recovery system is described, which includes a heat exchanger that transfers heat from a waste heat source to a pre-heated high temperature compressed fluid while generating a high temperature fluid and a partially cooled waste heat stream. A high temperature fluid expander expands the high temperature fluid to generate a high temperature expanded fluid. A multi- stream heat exchanger simultaneously transfers heat from the high temperature expanded fluid and the partially cooled waste heat stream to a low temperature, high pressure fluid while generating a low temperature waste heat stream, low temperature expanded fluid and a high temperature compressed fluid. The low temperature expanded fluid is cooled in a heat exchanger and compressed using a pressure raising system to produce a low temperature, high pressure fluid. The low temperature, high pressure fluid is fed into the multi- stream heat exchanger to complete the cycle.
F01K 23/10 - Plants characterised by more than one engine delivering power external to the plant, the engines being driven by different fluids the engine cycles being thermally coupled combustion heat from one cycle heating the fluid in another cycle with exhaust fluid of one cycle heating the fluid in another cycle
F25B 27/02 - Machines, plants or systems, using particular sources of energy using waste heat, e.g. from internal-combustion engines
F01K 17/06 - Returning energy of steam, in exchanged form, to process, e.g. use of exhaust steam for drying solid fuel of plant
F01K 3/18 - Plants characterised by the use of steam or heat accumulators, or intermediate steam heaters, therein having heaters
F01K 7/02 - Steam engine plants characterised by the use of specific types of engine; Plants or engines characterised by their use of special steam systems, cycles or processes; Control means specially adapted for such systems, cycles or processes; Use of withdrawn or exhaust steam for feed-water heating the engines being of multiple-expansion type
F01K 7/22 - Steam engine plants characterised by the use of specific types of engine; Plants or engines characterised by their use of special steam systems, cycles or processes; Control means specially adapted for such systems, cycles or processes; Use of withdrawn or exhaust steam for feed-water heating the engines being only of turbine type the turbines having inter-stage steam heating
F01K 7/44 - Use of steam for feed-water heating and another purpose
Present disclosure generally relates to devices and methods for conveying small amounts of fluids, and particularly relates to apparatus and method for scalable fluid delivery to achieve minimal motion of syringe plunger using multiple kinematic chain elements/pathways actuated by a single Motion Actuating Device (MAD). The scalable fluid delivery apparatus provides first kinematic pathway corresponding to high linear resolution mode of Piston Drive Member (PDM) and second kinematic pathway corresponding to low linear resolution mode of PDM. The first kinematic pathway includes final step of delivering fluid comprised in syringe, upon pushing plunger, and second kinematic pathway includes final step of performing forward motion or reverse motion of PDM. Forward motion, or reverse motion of PDM is for priming barrel and removable fluid delivery tube or to revert the PDM to an initial position, respectively, or to deliver the fluid.
A61M 5/168 - Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters
A61M 5/48 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests having means for varying, regulating, indicating or limiting injection pressure
36.
SYSTEM TO TRACK HOT-SECTION FLOWPATH COMPONENTS IN ASSEMBLED CONDITION USING HIGH TEMPERATURE MATERIAL MARKERS
There is provided markers, systems, and methods for creating and utilizing a marker containing identification information. The embodiments include an identifying marker comprised of high temperature material for tracking a component in a high temperature environment. The marker may be disposed on the component such that the marker is subject to high temperatures while affixed to the component. The marker may provide the ability to track a history of the component the marker is attached to for maintenance.
C23C 16/00 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition (CVD) processes
C23C 14/00 - Coating by vacuum evaporation, by sputtering or by ion implantation of the coating forming material
G06K 19/00 - Record carriers for use with machines and with at least a part designed to carry digital markings
G06Q 10/08 - Logistics, e.g. warehousing, loading or distribution; Inventory or stock management
B42D 25/36 - Identification or security features, e.g. for preventing forgery comprising special materials
The present disclosure relates to an efficient method of water splitting for large/industrial scale production of oxygen at the anode in an electrolyzer, while at the same time permitting hydrogen production at the cathode of the same electrolyzer. More particularly, the present disclosure provides optimal operating conditions such as temperature, pressure, and pH for a range of potentials for an electrochemical water splitting reactor to generate the maximum amount of oxygen at a given voltage while supplying the minimum possible amount of alkali.
A method for fabricating an antimicrobial layer on a fabric and a coated fabric thereof is disclosed. The method involves preparation of a layer of the fabric. The layer of the fabric is then coated with the radiation resistant layer and an antimicrobial layer. The radiation resistant properties are conferred by a coating of a resin mixture produced by using graphite nanoplatelets (GNP). The antimicrobial properties are conferred by a coating of a concoction produced by mixing a predetermined weight by volume percentage [wt/vol%] of a fibre-forming polymer (to form fibres), a polyelectrolyte, and a metal oxide (to confer antimicrobial properties).
B32B 33/00 - Layered products characterised by particular properties or particular surface features, e.g. particular surface coatings; Layered products designed for particular purposes not covered by another single class
D06M 16/00 - Biochemical treatment of fibres, threads, yarns, fabrics or fibrous goods made from such materials, e.g. enzymatic
39.
COMBINATION THERAPY COMPRISING CALCIMYCIN, ROMIDEPSIN, PANOBINOSTAT, OR A-1331852 AND CHEMOTHERAPEUTIC AGENTS FOR TREATMENT OF CANCER
The present disclosure provides a combination comprising a therapeutic compound selected from calcimycin, romidepsin, panobinostat, and A-1331852 and one or more chemotherapeutic agents selected from a platinum compound (e.g., carboplatin, cisplatin, and oxaliplatin) and a taxane (paclitaxel, docetaxel, and cabazitaxel). The present combinations have been identified using three-dimensional spheroid-based assays that mimic the metastatic niche of advanced stage cancers. The present disclosure also provides a method for treating cancer in a subject comprising administering said combinations to the subject. The combinations of the present disclosure show a synergistic cytotoxic activity against cancer cells.
The present disclosure relates to a system for additive manufacturing. The system includes a frame, a CNC bed configured with the frame. A metal dispensing mechanism configured to eject metal droplets on the CNC bed. The metal dispensing mechanism is configured to controllably move with respect to the CNC bed for manufacturing the object. The metal dispensing mechanism includes a first nozzle, functionally configured with the CNC bed, for controllably dispensing the metal droplets on the CNC bed, and the nozzle is fluidically configured with a reservoir having the metal. A piston configured with the reservoir, and the piston is configured to push the molten metal from the reservoir such the molten metal is released from the reservoir towards the first nozzle. The piston is made of thermally insulating material, and a transducer configured with the piston to facilitate mechanical jerking of the piston for facilitating the pushing of the molten metal from the reservoir.
B29C 64/112 - Processes of additive manufacturing using only liquids or viscous materials, e.g. depositing a continuous bead of viscous material using individual droplets, e.g. from jetting heads
B29C 64/00 - Additive manufacturing, i.e. manufacturing of three-dimensional [3D] objects by additive deposition, additive agglomeration or additive layering, e.g. by 3D printing, stereolithography or selective laser sintering
41.
NANO AND MICRO-PARTICLES TO PROMOTE PHAGOCYTIC ACTIVITY OF AN IMMUNE CELL
The present disclosure provides particles having a size of about 5nm to 5 µ, wherein said particles prime immune cells for phagocytosis. Said priming of immune cells by the particles of the present disclosure is accompanied by minimal or no release of proinflammatory mediators. The inventors observed that immune cells primed with the particles of the present disclosure or compositions comprising them show enhanced subsequent uptake of particulate matter compared to immune cells not primed with the particles or compositions thereof. The present disclosure exploits this phenomenon of enhanced sequential uptake for clearance of particulate matter such as clearance of microorganisms or for wound healing (clearance of apoptotic or injured cells and debris).
The present invention provides shortening TB Therapy and reducing relapse by co-administering Chloroquine with anti-TB drugs to drug-sensitive TB patients, multiple drug resistant (MDR) TB patients and TB patients co-infected with HIV-1. The present invention also provides shortening TB Therapy and reducing relapse by co-administering hydroxychloroquine with anti-TB drugs to drug-sensitive TB patients, multiple drug resistant (MDR) TB patients and TB patients co-infected with HIV-1.
A61K 31/454 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
A61K 31/506 - Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
A61K 31/4545 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
A61K 31/5415 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and at least one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
A61K 31/132 - Amines, e.g. amantadine having two or more amino groups, e.g. spermidine, putrescine
A61K 31/498 - Pyrazines or piperazines ortho- or peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
A61K 31/175 - Amides, e.g. hydroxamic acids having the group N—C(O)—N or N—C(S)—N, e.g. urea, thiourea, carmustine having the group , N—C(O)—N=N— or , e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
A61K 31/4709 - Non-condensed quinolines containing further heterocyclic rings
A61K 31/675 - Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
A61K 31/5377 - 1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
A61K 31/541 - Non-condensed thiazines containing further heterocyclic rings
A61P 31/06 - Antibacterial agents for tuberculosis
The present disclosure provides a layered composition comprising a) chitosan as a base layer; and b) a nanocomposite layer as a bioactive layer, wherein the nanocomposite layer comprises silica nanoparticles dispersed in silk fibroin. The present disclosure also provides a process of preparing the layered composition. The present disclosure further provides a hemostatic article, its use, and methods thereof.
A61K 47/00 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
44.
MICROWAVE-ASSISTED APPARATUS, SYSTEM AND METHOD FOR DEPOSITION OF FILMS ON SUBSTRATES
Indian Space Research Organization Headquarters (India)
Inventor
Sai, Ranajit
Shivshankar, Srinivasarao Ajjampur
Manish, Kumar Hooda
Abstract
The present invention provides an apparatus for the deposition of thin films on a substrate, including large substrates, held preferably face-down, in a cartridge containing a liquid solution with at least a chemical precursor which, upon being subject to a uniform microwave field transmitted through a microwave-transparent window, leads to the formation of a thin film on the substrate. The present invention also provides a system for launching microwaves and controlling the process for film deposition on the substrate. The present invention also provides a process for obtaining a film of uniform thickness and characteristics on a substrate or for incorporating controlled non-uniformity. The present invention also provides an apparatus and method for film deposition on a series of substrates in a continuous batch process.
C23C 18/14 - Decomposition by irradiation, e.g. photolysis, particle radiation
C23C 18/12 - Chemical coating by decomposition of either liquid compounds or solutions of the coating forming compounds, without leaving reaction products of surface material in the coating; Contact plating by thermal decomposition characterised by the deposition of inorganic material other than metallic material
b) connectable to the support plate (102), the circular motion of at least one of the support plate (102) and the ring member (103), relative to each other, moves the plurality of flexible beam assemblies (104) radially inward and radially outward to selectively apply radial resistance on the simulation endoscope (101). The complaint mechanism (100) of present disclosure are joint less mechanisms which are free from backlash and friction in joints.
G09B 23/28 - Models for scientific, medical, or mathematical purposes, e.g. full-sized device for demonstration purposes for medicine
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
G09B 9/00 - Simulators for teaching or training purposes
46.
METHOD, SYSTEM AND ELECTRONIC WEARABLE UNIT FOR CONTROLLING ELECTRICAL STIMULATION TO PELVIC REGION OF SUBJECT
Disclosed herein a method, tin Electrical Stimulation System (ESS) 101, and an electronic wearable unit 301 for controlling an electrical stimulation 113 to a pelvic region of a subject 103. The electronic wearable unit 301 comprises a non-skm contacting outer surface 307, a skin contacting inner surface 305 with a crotch part for removably attaching a urine collecting device 309, and the ESS 101 removably placed within a space bounded by the outer surface 307 and the inner surface 305. An input 105 for initiating a session is received. Further, at least one of, an activity level 107 of muscles in and around the pelvic region, an orientation 109 of one or more of the muscles, and a body posture 111 of the subject 103 is received, throughout the session. Based on the determination, the electrical stimulation 113 to the pelvic region of the subject 103 is controlled. Thus, the present disclosure enables portable administration of treatment, and further enables extending the electrical stimulation 113 from portable use in a fixed, body posture to ambulatory use, in multiple body postures.
Disclosed herein a method, tin Electrical Stimulation System (ESS) 101, and an electronic wearable unit 301 for controlling an electrical stimulation 113 to a pelvic region of a subject 103. The electronic wearable unit 301 comprises a non-skm contacting outer surface 307, a skin contacting inner surface 305 with a crotch part for removably attaching a urine collecting device 309, and the ESS 101 removably placed within a space bounded by the outer surface 307 and the inner surface 305. An input 105 for initiating a session is received. Further, at least one of, an activity level 107 of muscles in and around the pelvic region, an orientation 109 of one or more of the muscles, and a body posture 111 of the subject 103 is received, throughout the session. Based on the determination, the electrical stimulation 113 to the pelvic region of the subject 103 is controlled. Thus, the present disclosure enables portable administration of treatment, and further enables extending the electrical stimulation 113 from portable use in a fixed, body posture to ambulatory use, in multiple body postures.
F01K 25/10 - Plants or engines characterised by use of special working fluids, not otherwise provided for; Plants operating in closed cycles and not otherwise provided for using special vapours the vapours being cold, e.g. ammonia, carbon dioxide, ether
F01K 7/00 - Steam engine plants characterised by the use of specific types of engine; Plants or engines characterised by their use of special steam systems, cycles or processes; Control means specially adapted for such systems, cycles or processes; Use of withdrawn or exhaust steam for feed-water heating
49.
Method and system for recognizing activities in surrounding environment for controlling navigation of autonomous vehicle
A method and activity recognition system for recognising activities in surrounding environment for controlling navigation of an autonomous vehicle is disclosed. The activity recognition system receives first data feed from neuromorphic event-based camera and second data feed from frame-based RGB video camera. The first data feed comprises high-speed temporal information encoding motion associated with change in surrounding environment at each spatial location, and second data feed comprises spatio-temporal data providing scene-level contextual information associated with surrounding environment. An adaptive sampling of second data feed is performed with respect to foreground activity rate based on amount of foreground motion encoded in first data feed. Further, the activity recognition system recognizes activities associated with at least one object in surrounding environment by identifying correlation between both data feed by using two-stream neural network model. Thereafter, based on the determined activities, the activity recognition system controls the navigation of the autonomous vehicle.
The present disclosure discloses a method (200) of manufacturing an energy exchanging device (100). The method includes defining a plurality of through slots (14, 17) in a plurality of plates (2) by a through cut machining process, in which, each of the plurality of through slots define a flow channel. The method further includes stacking the plurality of plates (2) with at least one blanking member (24) positioned therebetween. Such stacking of the plurality of plates (2) forms a plurality of fluid flow paths about the plurality of through slots. The method further includes bonding the at least one blanking member with the plurality of plates, to form an energy exchanging core (1). The method further includes defining at least two inlet ports (45a, 45b) and at least two outlet ports (46a, 46b) in the core, for flow of fluid along the plurality of fluid flow paths within the core.
F28D 1/053 - Heat-exchange apparatus having stationary conduit assemblies for one heat-exchange medium only, the media being in contact with different sides of the conduit wall, in which the other heat-exchange medium is a large body of fluid, e.g. domestic or mo with the heat-exchange conduits immersed in the body of fluid with tubular conduits the conduits being straight
F28F 3/08 - Elements constructed for building-up into stacks, e.g. capable of being taken apart for cleaning
51.
METAL MATRIX POLYMER DERIVED CERAMIC COMPOSITES, PROCESSES OF PRODUCTION AND USES THEREOF
The present invention is in the field of metal matrix polymer derived ceramic composites, processes of production and uses thereof. In particular, the invention concerns metal matrix polymer derived ceramic composites comprising ceramic nanoparticles, processes of production comprising a step of severe plastic deformation, and uses thereof.
C22C 1/05 - Mixtures of metal powder with non-metallic powder
C22C 32/00 - Non-ferrous alloys containing at least 5% by weight but less than 50% by weight of oxides, carbides, borides, nitrides, silicides or other metal compounds, e.g. oxynitrides, sulfides, whether added as such or formed in situ
52.
A SYSTEM AND METHOD FOR SYNTHESIZING LOW-COST EPOXY COMPOSITES FOR ELECTROMAGNETIC INTERFERENCE SHIELDING APPLICATIONS
The embodiments herein disclose a system and method for developing a low-cost composite sheet for EMI shielding applications. A composite sheet is developed comprising of a continuous matrix with randomly dispersed conductive particulates such as carbon derivatives like carbon nanotubes (MWCNTs), exfoliated graphite (EG), and graphite nanoplatelets (GNPs) therein along with a flexible graphite sheet. The composite sheets are formable and are of sufficient strength to act as structural components and are suitable for use in automotive components that require efficient EMI shielding.
The present disclosure provides in vitro methods for identifying the presence or absence of haemoglobin S (HbS) or haemoglobin C (HbC) in a blood sample, kits and devices thereof. The inventors have found that HbS shows a substantial decrease in absorption under deoxygenated conditions compared to oxygenated conditions. The inventors expect HbC to show a similar decrease in absorption under deoxygenated conditions compared to oxygenated conditions. The methods, kits and devices of the disclosure employ this decrease in absorption under deoxygenated conditions to identify the presence or absence of HbS or HbC in a blood sample. The methods, kits and devices of the present disclosure are simple, low cost, and provide a rapid way to identify the presence or absence of HbS or HbC in a blood sample in a point-of-care setting.
G01N 33/72 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. hemoglobin, bilirubin
G01N 21/31 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
G01N 33/49 - Physical analysis of biological material of liquid biological material blood
54.
A METHOD FOR LOCOMOTION OF A NANOROBOT AND IMPLEMENTATIONS THEREOF
The present disclosure relates to a method for locomotion of at least one nanorobot through a biochemical environment. The present disclosure also reveals a method for locomotion of nanorobots for use in drug delivery, delivery of materials for medical imaging and medical diagnosis.
A61B 34/00 - Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
H01F 10/14 - Thin magnetic films, e.g. of one-domain structure characterised by magnetic layers characterised by the composition being metals or alloys containing iron or nickel
The present disclosure provides an edible electronic device for diagnostics of a patient. The edible electronic device communicates an external transceiver unit worn on the body of the patient or in close proximity of the patient. The edible electronic device slowly disintegrates in the patient's body and senses desired clinical parameters. The edible electronic device communicates the clinical parameters to the external transceiver unit. The external transceiver unit transmits the clinical parameters to an external device. The edible electronic device comprises a battery, a sensor, a signal modulation unit, and a communication unit, all built using edible materials. The edible electronic device is therefore safely digested and eliminated by the patient. The edible electronic device is safe to use without medical intervention.
Present disclosure discloses a system for separating hydrogen from feed gas. The system includes at least one compressor adapted to pressurize the feed gas to predefined pressure. One or more adsorber columns are fluidly coupled to the compressor and are adapted to receive the pressurized feed gas, where the adsorber columns include a body and an adsorber bed, which is disposed within the body. The adsorber bed is configured to separate hydrogen from the feed gas. Further, the one or more adsorber columns includes a plurality of channels defined in at least one of the adsorber bed and adjacently along a length of the adsorber bed, where the channels are configured to channelize the hydrogen and regulate temperature of the adsorber bed. The configuration of the system aids in extracting pure hydrogen at low feed gas pressure.
B01D 53/04 - Separation of gases or vapours; Recovering vapours of volatile solvents from gases; Chemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by adsorption, e.g. preparative gas chromatography with stationary adsorbents
57.
A FILTRATION SYSTEM FOR REMOVING CONTAMINANTS FROM A GASEOUS MEDIA AND A METHOD THEREOF
A filtration system for removing contaminants from a gaseous media is disclosed. A gas inlet (Ig) and a gas outlet (Og) is fluidly connected to the housing (110). A compressor (120) and a blower (130) are connected to the housing (110). One or more filter cartridges (200) are arranged in the housing (110). The suction within the housing (110) coats the one or more filter cartridges (200) with at least one pre-coat material. The pre-coat material removes contaminants from the gaseous media passing from the gas inlet (Ig). Further, the gaseous media is re-directed to another housing (110) when pressure drops beyond a pre-determined threshold value across the one of the housings (110). Subsequently, compressed air dislodges the pre-coat material from the one or more filter cartridges (200) for de-coating the one or more filter cartridges (200).
B01D 29/50 - Filters with filtering elements stationary during filtration, e.g. pressure or suction filters, not covered by groups ; Filtering elements therefor with multiple filtering elements, characterised by their mutual disposition
B01D 46/00 - Filters or filtering processes specially modified for separating dispersed particles from gases or vapours
58.
SILVER NANO-INK COMPOSITION COMPRISING MIXED-PHASE CAPPED NANOPARTICLES, METHODS OF PREPARATION, KIT AND APPLICATIONS THEREOF
The present disclosure generally relates to the field of printed electronics and conducting nano-inks. Particularly, the present disclosure provides for a printable nano-ink composition comprising plurality of mixed-phase capped nanoparticles. Each of the capped nanoparticles of the disclosure have a mixed phase of silver and silver oxide, that results in desirable properties for the nano-ink The present disclosure also provides for a method of preparing the said nanoparticles and the nano-ink composition, and applications thereof. The nanoparticles have good shelf life and can thus be stored unchanged for long time. Further, the ink can be flawlessly printed and can be converted to high conducting metallic silver at temperatures of about 150 °C or lower.
The present disclosure provides methods for inhibiting entry of a virus into a host cell using picolinic acid or a salt or derivative thereof. The present disclosure also provides methods for treating or preventing a viral infection in a subject by administering picolinic acid or a salt or derivative thereof. In particular, the methods of the present disclosure are effective for enveloped viruses and syncytium-forming viruses. In some embodiments, the present disclosure provides methods of treating or preventing a SARS CoV-2, Influenza A virus, human parainfluenza virus, herpes simplex virus, Japanese encephalitis virus, Zika virus, or a flavivirus infection.
Present disclosure discloses a system (100) and a method for processing biomass. The system comprises a reaction chamber (1) including a first chamber (1a) adapted to receive biomass bales from a loading station (2). The first chamber is configured to dry each of the plurality biomass bales by passage of a flue gas (FG) into the first chamber at a first predetermined temperature range and a first predetermined flue gas flux range. Further, a second chamber (1b) located adjacent to the first chamber receives biomass bales from the first chamber. Each biomass bale undergoes torrefaction at the second chamber by passage of the flue gas into the second chamber at a second predetermined temperature range and a second predetermined flue gas flux range. The system (100) eliminates need for preprocessing of biomass and provides a cost-effective solution for torrefaction of biomass in a single, compact vertical reaction chamber (1).
C10L 9/08 - Treating solid fuels to improve their combustion by heat treatment, e.g. calcining
F26B 17/16 - Machines or apparatus for drying materials in loose, plastic, or fluidised form, e.g. granules, staple fibres, with progressive movement with movement performed solely by gravity the materials passing down a heated surface
61.
Antiviral Applications of Picolinic Acid and its Derivatives
The present disclosure provides methods for inhibiting entry of a virus into a host cell using picolinic acid or a salt or derivative thereof. The present disclosure also provides methods for treating or preventing a viral infection in a subject by administering picolinic acid or a salt or derivative thereof. In particular, the methods of the present disclosure are effective for enveloped viruses and syncytium-forming viruses. In some embodiments, the present disclosure provides methods of treating or preventing a SARS CoV-2, Influenza A virus, human parainfluenza virus, herpes simplex virus, Japanese encephalitis virus, Zika virus, or a flavivirus infection.
Devices, systems and methods for controlling motion of magnetic-driven nanobots are provided. Based on a selection indicative of a pattern of movement of the nanobots (200), a signal can be generated indicative of a pattern of magnetic field to be produced. Electrical signals can be generated to cause production of the pattern of magnetic field. The electrical signals can be provided to a device (300, 800) which is adaptable for being placed on the head or around a tooth of the patient. A first coil (502, 602, 804) of the device can receive the electrical signals and produce the pattern of the magnetic field to drive the magnetically-driven nanobots from a pulp region of the tooth into the dentinal tubules.
The present disclosure relates to an engine (100) including a cylinder (102) that is filled with carbon dioxide. A first piston (104) is slidably configured inside the cylinder (102) and being configured to form a first cylinder (108) with a first end (130) of the cylinder (102). A second piston (106) is slidably configured inside the cylinder (102) and being configured to form a second cylinder (110) with a second end (132) of the cylinder (102). A heater (112) is circumferentially disposed around the first cylinder (108) and the first piston (104) is configured to expand a hot carbon dioxide received inside the first cylinder (108) from the heater (112). A cooler (116) is circumferentially disposed around the second cylinder (110) and second piston (104) is configured to compress a cold carbon dioxide received inside the second cylinder (110) from the cooler (116).
F01K 25/10 - Plants or engines characterised by use of special working fluids, not otherwise provided for; Plants operating in closed cycles and not otherwise provided for using special vapours the vapours being cold, e.g. ammonia, carbon dioxide, ether
F01B 7/16 - Machines or engines with two or more pistons reciprocating within same cylinder or within essentially coaxial cylinders with pistons synchronously moving in tandem arrangement
64.
HOMOGENIZED COHERENT EXCITATION OF A SAMPLE FOR DETERMINING MOLECULAR STRUCTURE
The invention provides a method for homogenized coherent excitation of a sample for determining molecular structure. The method includes selecting a monochromatic coherent light, homogenizing the monochromatic coherent light; irradiating the sample with the homogenized monochromatic light; collecting the Raman scattered light to obtain a profile and analyzing the profile to obtain chemical specific signature of the sample. The invention also provides a method for obtaining two dimensional imaging of a sample using irradiation of large sample area by homogenized monochromatic light without compromise in spatial resolution. A system for homogenized coherent excitation of a sample for determining molecular structure is also provided.
The method includes homogenizing a monochromatic coherent light source, irradiating the sample at plurality of points along all planes with the homogenized monochromatic light, collecting the molecular scattered light from all angles and planes to obtain a plurality of profile, resolving the plurality of profiles to obtain a molecular intensity maps, and reconstituting the intensity maps to obtain a three dimensional image of the sample. The system described is capable of obtaining molecular specific 3D morphology and profile of samples. The system described is capable of differentiating different chemicals or sample distribution throughout the 3D volume.
The present disclosure relates to nucleotide sequence selected from a group comprising sequence set forth as SEQ ID No. 1 and SEQ ID No. 2. The said nucleotide sequences possess promoter activity. The disclosure further relates to an expression vector comprising the nucleotide sequence, a host cell comprising the said expression vector. The disclosure further relates to method of producing a protein of interest or heterologous protein employing the expression vector. The method provides for simple, economical, and effective means of producing the protein of interest.
This disclosure relates to method and system for validating an Autonomous Vehicle (AV) stack. The method may include receiving an Operational Design Domain (ODD) and real-world data for evaluating at least one of an Advanced Driver Assistance System (ADAS) and the AV. The ODD is based on at least one feature of at least one of the ADAS and the AV. For each of a plurality of iterations, the method may further include generating a driving scenario based on the ODD of the AV and the real-world data through a Quality of Ride Experience (QoRE)-aware cognitive engine, plugging and running at least one of the ADAS and the AV algorithm based on the driving scenario, and determining a set of performance metrics corresponding to the at least one feature of at least one of the ADAS and the AV in the driving scenario based on the simulating.
B60W 50/00 - CONJOINT CONTROL OF VEHICLE SUB-UNITS OF DIFFERENT TYPE OR DIFFERENT FUNCTION; CONTROL SYSTEMS SPECIALLY ADAPTED FOR HYBRID VEHICLES; ROAD VEHICLE DRIVE CONTROL SYSTEMS FOR PURPOSES NOT RELATED TO THE CONTROL OF A PARTICULAR SUB-UNIT - Details of control systems for road vehicle drive control not related to the control of a particular sub-unit
B60W 50/06 - Improving the dynamic response of the control system, e.g. improving the speed of regulation or avoiding hunting or overshoot
B60W 60/00 - Drive control systems specially adapted for autonomous road vehicles
G07C 5/08 - Registering or indicating performance data other than driving, working, idle, or waiting time, with or without registering driving, working, idle, or waiting time
A system for man-machine interaction for a vehicle is disclosed. The proposed system includes an interactive reflected display on a windscreen of the vehicle; an eye tracking module including an eye gaze tracker for tracking eye gaze direction of a user, and a training unit to train the tracking module using a neural network to predict a real-time set of coordinates for eye gaze direction of the user based on a created reference data set of coordinates of the display; a finger tracking module to detect presence of a finger of the user and track movement of the finger; a cursor module configured to, on the basis of a received input, move a cursor on the display to an area of interest on the display; and a wireless switch module operatively coupled to the display for selecting a target in the area of interest on the display.
G06F 3/0346 - Pointing devices displaced or positioned by the user; Accessories therefor with detection of the device orientation or free movement in a 3D space, e.g. 3D mice, 6-DOF [six degrees of freedom] pointers using gyroscopes, accelerometers or tilt-sensors
B60K 35/00 - Arrangement or adaptations of instruments
G06F 3/01 - Input arrangements or combined input and output arrangements for interaction between user and computer
G06F 3/04812 - Interaction techniques based on cursor appearance or behaviour, e.g. being affected by the presence of displayed objects
G06F 3/0488 - Interaction techniques based on graphical user interfaces [GUI] using specific features provided by the input device, e.g. functions controlled by the rotation of a mouse with dual sensing arrangements, or of the nature of the input device, e.g. tap gestures based on pressure sensed by a digitiser using a touch-screen or digitiser, e.g. input of commands through traced gestures
B60K 35/29 - Instruments characterised by the way in which information is handled, e.g. showing information on plural displays or prioritising information according to driving conditions
M S RAMAIAH UNIVERSITY OF APPLIED SCIENCES (India)
Inventor
Barui, Srimanta
Shetty, Vibha
Basu, Bikramjit
Abstract
A dental implant assembly comprises, a base member which is rotatably insertable into a jaw-bone. The base member may be defined by a collar portion, a mid-portion and an apical region. The base member in entirety may be configured with a tapered configuration right from the mid-portion to the apical region. Further, the base member is defined with a plurality of threaded profiles on an outer surface. A first thread profile is defined on the collar portion. A second thread profile, defined on the mid-portion and a third thread profile, defined on the apical region. The third thread profile is configured to cut into the jaw-bone during insertion to anchor the base member. As the third thread profile cuts in to the jaw bone, the second thread profile forms a threaded hole within the drilled hole in order to securely anchor the base member within the jaw bone.
A61C 8/00 - Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
The invention provides a method of obtaining a biomarker for blood anomaly using Raman scattering. The method includes the first step of capturing atleast two unique Raman signatures with respect to the biomarker. The Raman signatures are obtained at regular interval. Second step is comparing the obtained unique Raman signatures to detect the change in the signature. Change in the Raman signature provides the indication for blood anomaly.
The invention provides a method for rapid detection of the viability of microorganisms. The method includes capturing a first unique signature with respect to a first lipid component, capturing a second unique signature with respect to a second lipid component, transforming each of the first lipid signatures and second lipid signatures to obtain amplified signatures, comparing the amplified signatures to obtain a first ratio and repeating the above mentioned steps at least one more time to obtain a second ratio. The alteration in the first ratio and the second ratio provides the indication for cardiovascular disorder.
The present invention provides a smart modular controller device. The smart modular controller device comprises a control board and a base circuit. Here, when the control board is mounted onto the base circuit, the control board auto recognizes the type and configuration of the base circuit and selects the relevant firmware mode of operation for quicker customization at individual module assembly. Each individual module is packaged in a casing and is mounted on a DIN rail. Further, the modules are stacked on a DIN rail and when the modules are mounted and pushed onto the existing stack, the serial connectors on the adjacent faces on the modules make contact and connectivity is established between the whole stack in series.
G05B 19/042 - Programme control other than numerical control, i.e. in sequence controllers or logic controllers using digital processors
G05B 13/02 - Adaptive control systems, i.e. systems automatically adjusting themselves to have a performance which is optimum according to some preassigned criterion electric
73.
GENERATING A KNOWLEDGE BASE FROM MATHEMATICAL FORMULAE IN TECHNICAL DOCUMENTS
A system (105) and method (200) for extracting mathematical formulae from the one or more technical documents is disclosed. The method comprises identifying variables and a concept associated with each of the variables from the one or more technical documents. The method comprises determining interdependencies between variables in the extracted mathematical formulae based on the identified variables and the concept associated with the variables. The method comprises generating the knowledge base based on the determined interdependencies. The method further comprises providing access to the knowledge base to an end-user.
An example heterostructure semiconductor for sensing a gas comprises a substrate made of nanosheets of a compound of a first metal, wherein the compound of the first metal is sensitive to the gas to be sensed; one or more 1-Dimensional (1D) components fabricated on a surface of the substrate, the 1D components comprising a compound of a second metal, wherein the compound of the second metal is selective to the gas to be sensed; and a 2-Dimensional (2D) layer formed on the surface of the substrate in portions excluding the 1D components, wherein the 2D layer comprises compounds of the first and second metal. Method of fabrication of the heterostructure semiconductor and a chemiresistive sensor made thereof are also disclosed.
G01N 27/12 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of a solid body in dependence upon reaction with a fluid
H01L 29/06 - Semiconductor bodies characterised by the shapes, relative sizes, or dispositions of the semiconductor regions
H01L 29/267 - Semiconductor bodies characterised by the materials of which they are formed including, apart from doping materials or other impurities, elements provided for in two or more of the groups , , , , in different semiconductor regions
H01L 21/02 - Manufacture or treatment of semiconductor devices or of parts thereof
The present subject matter provides a High Mobility Electron Transistor (HEMT) comprising: a substrate, a nucleation layer provided on the substrate, a channel layer, and a buffer layer formed between the nucleation layer and the channel layer. The buffer layer comprises a vertical stack of p-n junctions. Each p-n junction of the vertical stack of p-n junctions comprises an n-type layer provided on a p-type layer. The n-type layer and the p-type layer are parallel to the substrate.
The present disclosure provides a system (200) for rapid diagnosis of malignant lesions from biopsy tissue. The system comprises table-top platform (202) integrated with microsensors (206) and electronic modules for label-free and rapid phenotyping of extracted biopsy tissues using multiple modalities for a quick diagnosis, and to identify the margin for use inside the operation room. A multiple logistic regression model takes all the physical parameters measured as input variables to accurately predict the diagnosis. The electrical resistivity, thermal conductivity and mechanical stiffness of the extracted biopsy tissues are measured and used for performing the diagnostic delineation. The computations are performed on-board and the entire system can be controlled and actuated using a smart-phone.
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
77.
POLYPEPTIDE FRAGMENTS, IMMUNOGENIC COMPOSITION AGAINST SARS-CoV-2, AND IMPLEMENTATIONS THEREOF
The present disclosure discloses the polypeptide fragment having an amino acid sequence with at least 95% identity to the amino acid sequence selected from the group consisting of SEQ ID NO: 2, SEQ ID NO: 4, and SEQ ID NO: 6. The present disclosure also discloses nucleic acid fragment encoding the polypeptide fragment as described herein. Moreover, the present disclosure also discloses recombinant construct, recombinant vector and recombinant host cells. Also disclosed herein is an immunogenic composition comprising the polypeptide fragment as described herein, and a method for preparing the said immunogenic composition. The immunogenic composition is in form of vaccine. The polypeptide fragment and/or immunogenic composition is capable of eliciting protection against severe acute respiratory syndrome coronavirus 2. A kit comprising the polypeptide, or the immunogenic composition as described herein is also disclosed.
The present disclosure pertains to a sensor integrated diagnostic tool for management of pathological airway in paediatric population. The tool (200) can be used for characterizing the tracheal obstruction, such as stenosis, of varying grades and anomaly types. The tool (200) is a combination of an array of flow sensors (206) and an unfurling actuator (222) with radial arms that houses tactile sensors (208) at the tip of the arm. The flow sensor array (206) yields airflow patterns across various segments of the tracheobronchial tree and the unfurling actuator (222) measures patency with tactile sensors 208 capable of distinguishing between malacic and healthy tissue. The unfurler has radial arms that remain coiled inside the cylindrical casing at the distal tip (204). Upon actuation, the arms uncoil radially outward. The movement of the radial arms causes the tactile sensors (208) to contact the tracheal walls and gives a measure of the tracheal diameter.
The present invention relates to an in-vivo intraoperative probe (100) for brain tumour margin delineation comprising of biochip carrier (104), distal end (106), handle (108), low noise data transfer cable (112) with a multichannel connector (114) or wireless connectivity (Bluetooth, Wi-Fi, RF) to transfer the data from biochip/sensors (102) to an interface module (200). The present invention also relates to a method for delineate tumour margin based on measurements of an individual or multiple properties of brain tissues to detect tumour margin using an intraoperative probe.
A61B 5/05 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
The present disclosure relates to a breathing assistance apparatus for providing a breathing assistance to a user. The breathing assistance apparatus includes a first/second source configured with a first/second buffer. The first/second fluid is controllably transferred from the first/second source to the first/second buffer using any or combination of a first/second pressure regulators and one or more first/second valves. A mixing chamber configured with the first buffer and the second buffer to receive and mix the first fluid and the second fluid. A delivery tank configured with the mixing tank to controllably receive the third fluid through one or more fourth valves and a third pressure regulator. A user feed mask having an inlet configured with the delivery tank and user's face facilitating breathing assistance to the user.
444-linear (IZ4) spreading codes. The IZ4 family is efficient in terms of even and odd autocorrelation and cross-correlation as well as balance properties and compares very favourably with sequences employed by GPS and Beidou systems as judged by most common performance measures. The proposed system and the method do not need either padding or puncturing of bits to achieve the mandated period of 10230. Efficient shift-register techniques can be employed to generate the spreading codes.
G01S 19/24 - Acquisition or tracking of signals transmitted by the system
H04B 1/707 - Spread spectrum techniques using direct sequence modulation
G01S 19/03 - Cooperating elements; Interaction or communication between different cooperating elements or between cooperating elements and receivers
H03M 13/27 - Coding, decoding or code conversion, for error detection or error correction; Coding theory basic assumptions; Coding bounds; Error probability evaluation methods; Channel models; Simulation or testing of codes using interleaving techniques
Nano-sensors, nano-sensor array and methods of fabrication thereof are provided. A nano-sensor comprises a pair of sensing electrode assemblies aligned longitudinally along a first axis. Each sensing electrode assembly comprises an electrode strip coupled to a contact pad at a first end of the electrode strip. A sensing member is disposed between the pair of sensing electrode assemblies to detect, at a predetermined temperature, presence of a gaseous component. A thermally conductive layer is provided in contact with the sensing member. The nano-sensor comprises a heating assembly, comprising a heating strip disposed between and coupled to a pair of heating contact pads, aligned longitudinally along a second axis substantially perpendicular to the first axis. A portion of the heating strip is in contact with the thermally conductive layer to heat the sensing member through the thermally conductive layer.
G01N 27/18 - Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating impedance by investigating resistance of an electrically-heated body in dependence upon change of temperature caused by changes in the thermal conductivity of a surrounding material to be tested
83.
SYSTEM AND METHOD FOR MONITORING COGNITIVE LOAD OF A DRIVER OF A VEHICLE
A system and a method for monitoring cognitive load of a driver of a vehicle. The system comprises: a set of sensors (104) for sensing one or more ocular features of the driver; a cognitive engine (102) operatively coupled to the set of sensors (104), the cognitive engine (102) comprising a processor (202) coupled to a memory (204), the memory (204) storing instructions executable by the processor (202) to: determine one or more parameters value from the sensed one or more ocular features; and determine one or more deviation states based on processing of the determined one or more parameters value to enable real-time monitoring of cognitive load of the driver. The system is robust, accurate, fast, efficient, cost-effective and simple.
A61B 5/18 - Devices for psychotechnics; Testing reaction times for vehicle drivers
B60W 40/08 - Estimation or calculation of driving parameters for road vehicle drive control systems not related to the control of a particular sub-unit related to drivers or passengers
B60K 28/02 - Safety devices for propulsion-unit control, specially adapted for, or arranged in, vehicles, e.g. preventing fuel supply or ignition in the event of potentially dangerous conditions responsive to conditions relating to the driver
84.
A PROCESS AND DEVICE FOR FABRICATION OF HIGH TEMPERATURE SUPERCONDUCTORS
Processes and devices for fabrication of nanostructured superconductors are provided. A precursor of a first material is dispersed into a carrier gas to obtain a first aerosol. The first aerosol is contacted with a substrate. Decomposition of the first material is caused on contacting the first aerosol with the substrate to deposit the nanoparticles of the first material on the substrate to obtain a partially covered substrate. A second material is deposited on the partially covered substrate to form nanoclusters comprising the second material embedded in the first material to obtain the nanostructured superconductors.
B82B 1/00 - Nanostructures formed by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
B82B 3/00 - Manufacture or treatment of nanostructures by manipulation of individual atoms or molecules, or limited collections of atoms or molecules as discrete units
B82Y 30/00 - Nanotechnology for materials or surface science, e.g. nanocomposites
B82Y 40/00 - Manufacture or treatment of nanostructures
H01L 39/00 - Devices using superconductivity or hyperconductivity; Processes or apparatus specially adapted for the manufacture or treatment thereof or of parts thereof
85.
Microfluidic device with integrated micro-structured electrodes and methods thereof
The present disclosure provides a microfluidic device comprising a set of micro-structured electrodes. The electrodes are made of a fusible alloy such as Field's Metal and are patterned on a layer of PDMS. The molten fusible alloy is poured over the patterned PDMA layer and a suction force is applied to ensure uniformity of flow of the molten metal. A second layer comprising a flow channel orthogonal to the direction of the micro-structured electrodes is disposed under the first layer to form the microfluidic device. The device shows enhanced sensitivity to RBC detection at high frequencies that are also bio-compatible (above 2 MHz). Multiple layers of the micro-structures electrodes can be sandwiched between layers of flow channels to provide a 3D microfluidic device.
The present invention provides shortening TB Therapy and reducing relapse by co-administering Chloroquine with anti-TB drugs to drug-sensitive TB patients, multiple drug resistant (MDR) TB patients and TB patients co-infected with HIV-1. The present invention also provides shortening TB Therapy and reducing relapse by co-administering hydroxychloroquine with anti-TB drugs to drug-sensitive TB patients, multiple drug resistant (MDR) TB patients and TB patients co-infected with HIV-1.
The present disclosure provides a system for controlling operations of a joystick. The system includes: an input unit comprising a set of sensors, the set of sensors to sense input gestures and generate an input signal corresponding to the sensed input gestures; one or more rotary devices operatively coupled to one or more controlling pins of the joystick to move the corresponding controlling pins; and a control unit operatively coupled to the input unit and the one or more rotary devices, the control unit configured to: extract one or more attributes from the generated input signal; and generate a control signal by comparing the extracted one or more attributes with a dataset comprising a set of predefined attributes and corresponding control action, wherein the one or more rotary devices move the corresponding controlling pins in response to the generated control signals.
The present disclosure provides a portable apparatus to maintain temperature of an object comprising a first chamber containing a quantity of a thermal material. The first chamber is thermally coupled to a container holding the object of interest. Ambient air is driven over the thermal material and then towards the container to change the temperature of the container. A valve is provided near the container which can be opened to allow entry of ambient air towards the container. Either of the heated or cooled air flow and the operation of the valve is regulated to maintain the temperature of the container to within a predetermined temperature range. The container is configured to be sealed to isolate the object from the ambient and allows for a means to preserve object quality. A housing of the apparatus is provided with a provision to protect the first container from mechanical shocks.
The present invention provides an apparatus for the deposition of thin films on a substrate, including large substrates, held preferably face-down, in a cartridge containing a liquid solution with at least a chemical precursor which, upon being subject to a uniform microwave field transmitted through a microwave-transparent window, leads to the formation of a thin film on the substrate. The present invention also provides a system for launching microwaves and controlling the process for film deposition on the substrate. The present invention also provides a process for obtaining a film of uniform thickness and characteristics on a substrate or for incorporating controlled non-uniformity. The present invention also provides an apparatus and method for film deposition on a series of substrates in a continuous batch process.
A Drain Extended Tunnel FET (DeTFET) device is disclosed that outperforms state of art devices and can meet the requirements of High voltage/high power devices operating in the range of 5V-20V for System on Chip (SoC). The device comprises a P+ SiGe source with an N-type Si Epilayer sandwiched between SiGe source and the gate stack, which enables vertical tunneling of minority carriers from SiGe P+ source into N-Epi region under the influence of gate field. The area tunneling between SiGe source and Si Epi region breaks the barrier imposed by thermionic injection based carrier transport from source to channel, which exists in DeMOS devices known in the art. The disclosed device results in improved performance in respect of ON current, leakage, sub-threshold slope, breakdown voltage and RF characteristics making it attractive for SoC applications as compared to its state of the art counterparts.
H01L 29/78 - Field-effect transistors with field effect produced by an insulated gate
H01L 29/06 - Semiconductor bodies characterised by the shapes, relative sizes, or dispositions of the semiconductor regions
H01L 27/092 - Devices consisting of a plurality of semiconductor or other solid-state components formed in or on a common substrate including integrated passive circuit elements with at least one potential-jump barrier or surface barrier the substrate being a semiconductor body including only semiconductor components of a single kind including field-effect components only the components being field-effect transistors with insulated gate complementary MIS field-effect transistors
A clinical sample storage cassette and an assembly comprising the clinical sample storage cassette is provided. The clinical sample storage cassette can comprise a top layer, a distributor layer, and a storage membrane. The top layer can comprise a first side to receive a clinical sample and a second side coupled with a distributor layer. The distributor layer is to receive the clinical sample from the top layer. The distributor layer can comprise a first distributor side coupled to the second side and a second distributor side coupled to the storage membrane to transfer the clinical sample to the storage membrane. The distributor layer and the storage membrane can have different flow rates of the clinical sample to allow for uniform flow and storage of the clinical sample on the storage membrane.
The present disclosure provides a solid-state battery 100, which includes: an electrolyte layer 102 wherein at least at a first surface, the electrolyte layer is a solid-state electrolyte; a first electrode layer 106-1 disposed on a first side of the electrolyte layer; a second electrode layer 106-2 disposed on a second side of the electrolyte layer; and a first interlayer 108-1 made of a first material, disposed between the electrolyte layer and the first electrode layer. The first electrode layer has low solubility in the first material, which facilitates reduced nucleation of the first electrode layer at interface of the first interlayer with the electrolyte layer due to excessive activation energy for nucleation, and the reduced nucleation enables reduced formation of dendrites at the first electrode layer.
Methods of fabricating semiconductor stacks and semiconductor stacks obtained therefrom are provided. A substrate (102) is provided in a reactor. First precursors are supplied with a carrier gas to form a first layer (104) on the substrate (102) and the supply is stopped after the first layer (104) is formed. Second precursors and third precursors are supplied with the carrier gas to form a doped layer. The second precursors correspond to precursors which form an intrinsic semiconductor and the third precursors correspond to precursors which form a dopant. Supply of the second precursors and the third precursors is stopped. The carrier gas is continued to be supplied to remove a top surface of the doped layer to form a surface etched doped layer (106) to reduce diffusion of the dopant to subsequent layers.
H01L 21/20 - Deposition of semiconductor materials on a substrate, e.g. epitaxial growth
H01L 21/205 - Deposition of semiconductor materials on a substrate, e.g. epitaxial growth using reduction or decomposition of a gaseous compound yielding a solid condensate, i.e. chemical deposition
H01L 33/32 - Materials of the light emitting region containing only elements of group III and group V of the periodic system containing nitrogen
94.
SYSTEM AND METHOD FOR AUTONOMOUS NAVIGATION OF UNMANNED AERIAL VEHICLE (UAV) IN GPS DENIED ENVIRONMENT
An embodiment of the present disclosure provides a system and a method for autonomous navigation of an unmanned aerial vehicle (UAV) in a GPS denied environment. The method facilitates to enable configuration of at least one inference time constraint and a minimum desired accuracy, and compress a neural network model that has been previously trained using an existing dataset. The neural network model is compressed by generating scores for each artifact of the neural network model containing non-zero weights. Weights of a lowest ranked artifact are stored in a dictionary. Weights of said lowest ranked artifact are set to zero to effect a compressed neural network model. Neural network model is retrained for a plurality of iterations such that accuracy of the compressed neural network model is checked at each iteration, and the steps of generating scores and storing weight are repeated if the minimum desired accuracy is not violated.
The present disclosure relates to a method for locomotion of at least one nanorobot through a biochemical environment. The present disclosure also reveals a method for locomotion of nanorobots for use in drug delivery, delivery of materials for medical imaging and medical diagnosis.
A61B 34/00 - Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
H01F 41/20 - Apparatus or processes specially adapted for manufacturing or assembling magnets, inductances or transformers; Apparatus or processes specially adapted for manufacturing materials characterised by their magnetic properties for applying magnetic films to substrates by evaporation
H01F 10/14 - Thin magnetic films, e.g. of one-domain structure characterised by magnetic layers characterised by the composition being metals or alloys containing iron or nickel
A61B 17/00 - Surgical instruments, devices or methods, e.g. tourniquets
96.
SUPERCONDUCTING BLOCK, SUPERCONDUCTING NANOCRYSTAL, SUPERCONDUCTING DEVICE AND A PROCESS THEREOF
The present invention provides a superconducting block, comprising, a pair of cores with materials that are electrically conductive in their normal states. The pair of cores are embedded in the shell with an intervening centroidal distance, with a material that is electrically conductive in its normal state. The embedded pair of cores and the shell are configured to be superconductive. The present invention also provides a superconducting nanocrystal with at least the superconducting block. The present invention also provides a superconductive device with at least the superconducting block and the superconducting nanocrystal. The present invention further provides a process for fabricating the superconducting block and superconducting crystal. The present invention provides superconductors (superconducting block, superconducting nanocrystals) that can be employed to attain superconductivity at high temperatures, corresponding to temperatures existing in the terrestrial ambient and even higher.
H01B 12/00 - Superconductive or hyperconductive conductors, cables or transmission lines
H01L 39/08 - Devices using superconductivity or hyperconductivity; Processes or apparatus specially adapted for the manufacture or treatment thereof or of parts thereof - Details characterised by the shape of the element
97.
CONTROLLING MOTION OF MAGNETICALLY-DRIVEN MICROSCOPIC PARTICLES
Devices, systems and methods for controlling motion of magnetic-driven nanobots are provided. Based on a selection indicative of a pattern of movement of the nanobots (200), a signal can be generated indicative of a pattern of magnetic field to be produced. Electrical signals can be generated to cause production of the pattern of magnetic field. The electrical signals can be provided to a device (300, 800) which is adaptable for being placed on the head or around a tooth of the patient. A first coil (502, 602, 804) of the device can receive the electrical signals and produce the pattern of the magnetic field to drive the magnetically-driven nanobots from a pulp region of the tooth into the dentinal tubules.
This disclosure relates to methods of promoting immune responses against HIV and compositions related thereto. In certain embodiments, this disclosure relates to methods of vaccinating for HIV comprising administering to the subject a priming composition followed by a boosting composition. In certain embodiments, the priming composition comprises a recombinant virus such as recombinant MVA that encodes an Env protein of HIV or segment thereof. In certain embodiments, the boosting composition comprises a trimeric cyclically permuted gp120 chimeric protein reported herein or DNA encoding the same.
The subject matter of the present disclosure relates to nanostructured electrical conductor of metal nanoparticles that are dispersed in another metallic matrix and these electrical conductors exhibit a very low electrical resistance. The present invention also provides a process for the preparation of nanostructured electrical conductor exhibiting a very low resistance. The nanostructured electrical conductor is composed of nanoparticles of metal (e.g. silver) dispersed in another metallic matrix (e.g. gold), and their electrical resistivity is three decades or more below that of conventional highly conducting metals, such as gold, copper or silver. The low resistance of nanostructured electrical conductor can maintained up to 1000 K, depending on the composition, and under operating pressure.
H01B 1/02 - Conductors or conductive bodies characterised by the conductive materials; Selection of materials as conductors mainly consisting of metals or alloys
H01B 12/00 - Superconductive or hyperconductive conductors, cables or transmission lines
100.
A DESILTING APPARATUS FOR CLEANING A PRE-DEFINED VICINITY
A desilting apparatus for cleaning a pre-defined vicinity [0036] The present invention relates to desilting apparatus (100) for cleaning a pre-defined vicinity. The apparatus (100) comprises an operating unit (106) and a 5 control unit (105) to monitor and actuate desilting operation executed through the apparatus (100) by an operator. A grasping device (101) cleans silt and debris accumulated in a predefined vicinity by employing one or more jaw buckets (101a) which grabs silt accumulated in the pre-defined vicinity. A hydraulic system (103c) performs the moving operation of hoist assembly (103) by transmitting power to 10 different components in the desilting apparatus (100). Further, the hoist assembly (103) comprises flexible members (104b) to freely maneuver the grasping device (101) within the pre-defined vicinity thereby collecting silt and debris from the pre-defined vicinity and transmitting silt into storage bin (107) provided at the desilting apparatus (100).
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