Abstract

A method for ameliorating or treating Parkinson's disease includes administering a composition including an osmotin protein as effective component to a subject in need thereof. The composition has the effects of alleviating behavior and motor skill deficits induced by MPTP/α-synuclein, protecting dopaminergic neurons, regulating the expression level of neuroinflammation-related proteins, inhibiting apoptotic cell death induced by MPTP/α-synuclein, alleviating cell damage caused by overexpression of α-synuclein (A53T), reducing the accumulation of α-synuclein caused by activation of AMPK and subsequent autophagy, regulating the dendritic complex structure, increasing the spine density in pyramidal neurons, alleviating the cognitive deficits, and restoring the expression of synaptic markers. The osmotin protein can be advantageously used for a functional health food or a pharmaceutical product for preventing, ameliorating, or treating Parkinson's disease.

IPC Classes  ?

• A61K 38/16 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
• A61P 25/16 - Anti-Parkinson drugs

Abstract

The present invention relates to a method for producing a polyploid plant with quantitative traits adjusted by genetic editing, and a polyploid plant with adjusted quantitative traits, produced thereby. When the method according to the present invention is used, it is expected that varieties can be easily improved by adjusting quantitative traits of polyploid crops.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• C12N 9/22 - Ribonucleases
• C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants

Abstract

The present invention relates to a method for extracting, preparing, and producing phycocyanin by freezing and thawing Arthrospira platensis and using the autolysis reaction. When phycocyanin is extracted by using the method of the present invention, the extraction concentration, yield, and purity of phycocyanin are significantly increased.

IPC Classes  ?

• C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
• C12N 1/12 - Unicellular algaeCulture media therefor
• C12N 1/38 - Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factorsStimulation of growth by removal of a chemical compound
• A23L 5/43 - Addition of dyes or pigments, e.g. in combination with optical brighteners using naturally occurring organic dyes or pigments, their artificial duplicates or their derivatives
• A23L 33/195 - Proteins from microorganisms
• A23K 20/179 - Colouring agents, e.g. pigmenting or dyeing agents

Abstract

The present invention relates to a composition comprising a nucleotide with a 5'-untranslated region for enhanced gene expression and a method therefor. By utilizing the 5'-untranslated region exhibiting high translation efficiency, the present invention is expected to be applicable in designing mRNA vaccines for the prevention of various infectious diseases and mRNA therapeutics for the treatment of various diseases.

IPC Classes  ?

• C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression
• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
• A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
• A61K 39/00 - Medicinal preparations containing antigens or antibodies
• A61P 31/00 - Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Abstract

The present invention provides a laparoscopic specimen retrieval pack having a pattern structure enabling easy specimen retrieval. The present invention comprises: a retrieval pack having an inlet for introducing a specimen collected from the abdominal cavity and a collection hole having a space to contain the specimen, the space tapering gradually to be narrower than the diameter of the inlet; a check hole having a collection dome formed to have a volume smaller than the volume of the collection hole such that the collected specimen is received in a vertical position when the retrieval pack is retrieved using a laparoscope; and pattern lines arranged at a regular interval on the outer surface of the check hole so that the length of a receiving hole of the collection dome extends by the specimen in a vertical posture during the passage of the laparoscope.

IPC Classes  ?

• A61B 17/00 - Surgical instruments, devices or methods
• A61B 17/221 - Calculus gripping devices in the form of loops or baskets
• A61B 10/04 - Endoscopic instruments, e.g. catheter-type instruments

Abstract

The present invention relates to a low-concentration and low-viscosity ink for inkjet printing and a high-concentration and high-viscosity ink for dispenser printing, which are manufactured by using edge-oxidized graphene which can be safely dispersed in a solvent without a dispersant. In addition, the present invention relates to preparing a graphene-PEDOT:PSS nanocomposite ink by simply mixing edge-oxidized graphene, which can be safely dispersed in a solvent without a dispersant, with a PEDOT:PSS solution, and a transparent film having excellent electrical conductivity, which is manufactured using same. A film, which can be naturally dried in the air after printing without a post-treatment process and has excellent electrical conductivity and transparency, can be manufactured.

IPC Classes  ?

• C09D 11/52 - Electrically conductive inks
• C09D 11/32 - Inkjet printing inks characterised by colouring agents
• C09D 11/037 - Printing inks characterised by features other than the chemical nature of the binder characterised by the pigment
• C08K 3/04 - Carbon
• C08K 9/04 - Ingredients treated with organic substances
• H01B 1/12 - Conductors or conductive bodies characterised by the conductive materialsSelection of materials as conductors mainly consisting of other non-metallic substances organic substances
• H01B 1/24 - Conductive material dispersed in non-conductive organic material the conductive material comprising carbon-silicon compounds, carbon, or silicon
• H01B 5/14 - Non-insulated conductors or conductive bodies characterised by their form comprising conductive layers or films on insulating-supports

Abstract

The present invention pertains to a vanadium oxide-based cathode material for a zinc-ion battery, a method for producing same, and a zinc-ion battery including same. The vanadium oxide-based cathode material for a zinc-ion battery according to an embodiment of the present invention comprises: oxygen vacancy (Vo)-containing vanadium oxide nanoparticles; and water (H2O) intercalated in the lattice of the oxygen vacancy-containing vanadium oxide nanoparticles.

IPC Classes  ?

• H01M 4/48 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides
• H01M 4/02 - Electrodes composed of, or comprising, active material
• H01M 4/04 - Processes of manufacture in general
• H01M 4/66 - Selection of materials
• H01M 10/054 - Accumulators with insertion or intercalation of metals other than lithium, e.g. with magnesium or aluminium
• H01M 10/0562 - Solid materials
• H01M 10/44 - Methods for charging or discharging

Abstract

The present invention relates to a microneedle patch system for continuously administering a large amount of drug to the skin. A microneedle patch provided by one aspect of the present invention may have increased drug content per unit area (1 cm2) to maximum of 100 mg unlike existing microneedles and thus has a higher drug content per unit area than an existing transdermal absorption agent, and is capable of delivering the drug into the body for a short time (within 24 hours) and a long time (approximately three days or more) via micropores formed by means of microneedles.

IPC Classes  ?

• A61M 37/00 - Other apparatus for introducing media into the bodyPercutany, i.e. introducing medicines into the body by diffusion through the skin
• A61K 9/00 - Medicinal preparations characterised by special physical form

Abstract

The present invention relates to a composition for preventing or treating amebiasis, comprising, as an active ingredient, an extract of Xanthium orientale L., a fraction thereof, or a compound isolated therefrom. The composition for preventing or treating amebiasis, comprising an extract of Xanthium orientale L., a fraction thereof, or a compound isolated therefrom, of the present invention, induces morphological changes in Naegleria fowleri, reduces the survival rate of Naegleria fowleri, and ultimately induces the death thereof. Therefore, the extract of Xanthium orientale L., the fraction thereof or the compound isolated therefrom, according to the present invention, can be effectively used in a pharmaceutical composition or a health functional food composition for preventing or treating amebiasis.

IPC Classes  ?

• A61K 31/365 - Lactones
• A61K 31/37 - Coumarins, e.g. psoralen
• A61K 36/28 - Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
• A61P 33/04 - Amoebicides
• A23L 33/10 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives
• A61P 31/00 - Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
• A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives

Abstract

Disclosed is a dental surgery assistance device using augmented reality. The dental surgery assistance device using augmented reality according to an embodiment of the present invention comprises: a wearing device worn by a user; and an augmented reality device coupled to the wearing device to capture an image of a tooth region of a patient, project augmented reality content to the captured image, and output the projected content and image, wherein the augmented reality device further comprises: a camera unit for capturing an image of the tooth region of the patient; a communication unit for obtaining an oral image, a transmissive image, and dental surgery information from an external server; an augmented reality content generation unit for merging the obtained oral image and the obtained transmissive image to be overlapped correspondingly so as to generate a merged image and generating augmented reality content on the basis of the generated merged image and the obtained dental surgery information; and an augmented reality content provision unit for projecting the augmented reality content to the captured image to generate a dental surgery guide and outputting the generated dental surgery guide through a display unit.

IPC Classes  ?

• A61B 34/10 - Computer-aided planning, simulation or modelling of surgical operations
• A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
• A61B 90/50 - Supports for surgical instruments, e.g. articulated arms

Abstract

The present disclosure relates to a multi-functional heating sandwich composite based on electromagnetic wave absorption technology applicable to large wing structures and a method for manufacturing the same, and particularly, to a composite based on an electromagnetic wave absorption heating mechanism, which converts electromagnetic waves into thermal energy in order to solve the freezing problem, and a method for manufacturing the same. The present disclosure provides a multi-functional heating sandwich composite based on electromagnetic wave absorption technology applicable to large wing structures, including: a face skin formed to a predetermined thickness on the top or bottom of the composite to absorb electromagnetic waves applied from the outside; and a honeycomb core that converts the power loss of electromagnetic waves penetrating from the face skin into thermal energy and is formed in the shape of a hexagonal pillar with a predetermined thickness using metal electroless plated dielectric fibers having electrical conductivity, wherein the honeycomb core reduces reflected electromagnetic waves by dissipating the electromagnetic waves through periodic changes in impedance in a preset target frequency band.

IPC Classes  ?

• F01D 5/28 - Selecting particular materialsMeasures against erosion or corrosion
• B32B 3/12 - Layered products comprising a layer with external or internal discontinuities or unevennesses, or a layer of non-planar shapeLayered products comprising a layer having particular features of form characterised by a discontinuous layer, i.e. apertured or formed of separate pieces of material characterised by a layer of regularly-arranged cells whether integral or formed individually or by conjunction of separate strips, e.g. honeycomb structure
• B32B 5/02 - Layered products characterised by the non-homogeneity or physical structure of a layer characterised by structural features of a layer comprising fibres or filaments
• B32B 15/14 - Layered products essentially comprising metal next to a fibrous or filamentary layer
• B64D 15/12 - De-icing or preventing icing on exterior surfaces of aircraft by electric heating
• F03D 80/40 - Ice detectionDe-icing means

Abstract

in vitro in vitro model, and therefore, the active ingredient of the present invention can be effectively used as a medicine and a vaccine for the prevention or treatment of Parkinson's disease.

IPC Classes  ?

• A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
• A61K 47/64 - Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
• A61K 39/00 - Medicinal preparations containing antigens or antibodies
• A61P 25/16 - Anti-Parkinson drugs
• C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals

Abstract

GmFT4Glycine max GmFT6Glycine maxGlycine max FLOWERING LOCUS T 6) gene editing, and to an early flowering- or early maturation-derived, genome-edited soybean plant produced by the method.

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• C12N 9/22 - Ribonucleases
• C12N 15/10 - Processes for the isolation, preparation or purification of DNA or RNA
• A01H 5/10 - Seeds
• A01H 6/54 - Leguminosae or Fabaceae, e.g. soybean, alfalfa or peanut

Abstract

A method of preparing a bio-polyol using coffee by-products, a polyurethane resin composition containing the bio-polyol, and a method of preparing a polyurethane foam using the same are described. The method simplifies the complicated process of extracting polyols from coffee and thus extracts bio-polyols within a short time, thus being advantageous in terms of cost and time.

IPC Classes  ?

• C08G 65/46 - Post-polymerisation treatment, e.g. recovery, purification, drying
• C08G 18/08 - Processes
• C08G 18/20 - Heterocyclic aminesSalts thereof
• C08G 18/66 - Compounds of groups , , or
• C08G 18/72 - Polyisocyanates or polyisothiocyanates
• C08J 9/12 - Working-up of macromolecular substances to porous or cellular articles or materialsAfter-treatment thereof using blowing gases generated by a previously added blowing agent by a physical blowing agent

Abstract

The Streptomyces bacillaris S8 strain of the present invention has excellent antifungal activity against pathogens causing anthrax, root rot, late blight, and browning disease, and has an effect of increasing low-temperature stress resistance of grass.

IPC Classes  ?

• C12N 1/20 - BacteriaCulture media therefor
• A01N 63/28 - Streptomyces
• A01P 3/00 - Fungicides
• C12R 1/465 - Streptomyces

Abstract

The present invention relates to: a mRNA/DNA structure including a coding region encoding a target peptide or protein and an RNA/DNA hybrid structure; and to a pharmaceutical composition for vaccines or gene therapy, comprising the mRNA/DNA structure. The mRNA/DNA structure platform according to the present invention inhibits excessive immune responses caused by mRNA, consequently increasing protein expression, and thus can be widely used in the fields of mRNA vaccines and gene therapy.

IPC Classes  ?

• C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy

Abstract

The present disclosure relates to a stitched electromagnetic wave-absorbing composite for low-speed impact protection, and particularly, to a composite that exhibits electromagnetic wave absorption performance and low-speed impact protection performance at the same time by applying a stitching method, a thickness direction reinforcement method, to a composite that is an electromagnetic wave absorber. The present disclosure provides a stitched electromagnetic wave-absorbing composite for low-speed impact protection including a composite composed of at least one of glass fiber, epoxy, or glass fiber reinforced plastics (GFRP) in an electromagnetic wave-absorbing composite, wherein the composite absorbs electromagnetic waves, and has an impact protection system applied thereto through stitching.

IPC Classes  ?

• B29C 70/22 - Fibrous reinforcements only characterised by the structure of fibrous reinforcements using fibres of substantial or continuous length oriented in at least two directions forming a two dimensional structure
• B29K 63/00 - Use of epoxy resins as moulding material
• B29K 105/08 - Condition, form or state of moulded material containing reinforcements, fillers or inserts of continuous length, e.g. cords, rovings, mats, fabrics, strands or yarns
• B29K 309/08 - Glass

Abstract

The present invention relates to a method for measuring rheological properties of a fluid by using a rotating body having any shape, the method, more specifically, comprising: a shape coefficient derivation step of deriving a shape coefficient of the rotating body on the basis of the motion characteristics of the rotating body for a fluid of which rheological properties are known; a motion measurement step in which a measurement unit measures motion information of the rotating body moving under preset conditions while the rotating body is in contact with the fluid of which rheological properties are to be measured in a container; and a rheological property calculation step of calculating rheological property information of the fluid to be measured on the basis of the shape coefficient of the rotating body and the motion information of the rotating body. In addition, according to the present invention, linear and nonlinear viscoelastic data measured under oscillatory shear flow, which was thought to only be possible by means of expensive and cutting-edge equipment such as a rheometer, can be measured without a rheometer. Furthermore, the present invention can be installed directly at an industrial site (on-site) for process control for processing complex fluids, and has the effect of enabling the rheological properties including viscoelastic behavior of complex fluids to be monitored in real time in-situ.

IPC Classes  ?

• G01N 11/14 - Investigating flow properties of materials, e.g. viscosity or plasticityAnalysing materials by determining flow properties by moving a body within the material by using rotary bodies, e.g. vane
• G01N 11/00 - Investigating flow properties of materials, e.g. viscosity or plasticityAnalysing materials by determining flow properties

Abstract

The present invention relates to: a potato virus Y-derived fusion tag for increasing the soluble expression of a target protein; and a use thereof. A PVY fusion tag according the present invention can increase the amount of soluble expression of a target protein fused to a C-terminus of the fusion tag and can thus be used as a fundamental component of a vector system for expressing recombinant proteins for pharmaceutical, industrial, and research purposes.

IPC Classes  ?

• C07K 14/005 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from viruses
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C12N 9/18 - Carboxylic ester hydrolases

Abstract

A light-emitting device including a first electrode, a second electrode facing the first electrode, an interlayer, and an organometallic compound is provided. The interlayer is between the first electrode and the second electrode and includes an emission layer.

IPC Classes  ?

• H10K 85/30 - Coordination compounds
• C07F 15/00 - Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
• C09K 11/06 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials
• H10K 50/12 - OLEDs or polymer light-emitting diodes [PLED] characterised by the electroluminescent [EL] layers comprising dopants
• H10K 101/20 - Delayed fluorescence emission

Abstract

In a method for guiding an implant surgery using augmented reality and a device for performing same according to an embodiment of the present invention, the device is a computing device comprising one or more processors, and a memory storing one or more programs executed by the one or more processors and comprises: an image obtainment module that obtains an oral image and a transmission image; an image merging module that generates a merged image by merging the obtained oral image and the obtained transmission image so that the images correspond to and overlap each other; an augmented reality content production module that generates augmented reality content on the basis of the generated merged image and previously generated implant surgery information; and an augmented reality content provision module that obtains, from an augmented reality device, a captured image of a tooth area of a patient and provides, to a user, an implant surgery guide by projecting the augmented reality content onto the obtained captured image.

IPC Classes  ?

• A61B 34/10 - Computer-aided planning, simulation or modelling of surgical operations
• A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
• A61B 90/50 - Supports for surgical instruments, e.g. articulated arms
• A61C 9/00 - Impression methods specially adapted for dental prostheticsImpression cups therefor

Abstract

In a method for guiding tooth preparation by using augmented reality, and an apparatus for performing same, according to one embodiment of the present invention, the apparatus is a computing apparatus including one or more processors and a memory for storing one or more programs to be executed by means of the one or more processors, and comprises: an image acquisition module for acquiring an oral image and a transmission image; an image-merging module for generating a merged image by merging the acquired oral image and the acquired transmission image such that same are correspondingly superimposed; an augmented reality content production module for generating augmented reality content on the basis of the generated merged image and pre-generated tooth preparation information; and an augmented reality content provision module which acquires, from an augmented reality device, a captured image obtained by imaging a tooth area of a patient, and which projects the augmented reality content onto the acquired captured image so as to provide a tooth preparation guide to a user.

IPC Classes  ?

• A61C 1/08 - Machine parts specially adapted for dentistry
• A61C 9/00 - Impression methods specially adapted for dental prostheticsImpression cups therefor
• A61C 3/02 - Tooth drilling or cutting instrumentsInstruments acting like a sandblast machine
• G06N 20/00 - Machine learning
• G02B 27/01 - Head-up displays
• G06T 19/00 - Manipulating 3D models or images for computer graphics
• G16H 30/00 - ICT specially adapted for the handling or processing of medical images
• G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
• A61C 13/00 - Dental prosthesesMaking same
• B33Y 80/00 - Products made by additive manufacturing

Abstract

According to an embodiment of the present invention, a method for guiding endodontic treatment using augmented reality and a device for performing same are provided, the device being a computing device provided with at least one processor and a memory for storing one or more programs that are executed by the at least one processor, and comprising: an image acquisition module that acquires an oral image and a transmission image; an image merging module that merges the acquired oral image and transmission image so that the images correspondingly overlap, thereby generating a merged image; an augmented reality content production module that generates augmented reality content on the basis of the generated merged image and pre-generated endodontic treatment information; and an augmented reality content providing module that acquires a captured image of a tooth area of a patient from an augmented reality device and projects the augmented reality content onto the acquired captured image to provide an endodontic treatment guide.

IPC Classes  ?

• A61B 34/10 - Computer-aided planning, simulation or modelling of surgical operations
• A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
• A61B 90/50 - Supports for surgical instruments, e.g. articulated arms
• A61C 5/40 - Implements for surgical treatment of the roots or nerves of the teethNerve needlesMethods or instruments for medication of the roots

Abstract

The present invention relates: to a hydroxy group-based polymeric binder for a sulfur battery that can effectively suppress the elution of polysulfides, generated by the reduction of sulfur during a discharge process, into an electrolyte, thereby solving the problem of poor life characteristics of a sulfur battery as a result; and to a sulfur battery positive electrode and a sulfur battery comprising same. The polymeric binder for a sulfur battery according to one embodiment of the invention is characterized by being prepared through a chemical reaction between a water-soluble polymer and a hydroxyl group-based crosslinker represented by the formula M(OH)n, wherein M is a metal or metalloid, and n is an integer from 1 to 5. In addition, the present invention relates: to a carboxylic acid-based polymeric binder for a sulfur battery that can effectively suppress the elution of polysulfides, generated by the reduction of sulfur during a discharge process, into an electrolyte, thereby solving the problem of poor life characteristics of a sulfur battery as a result; and to a sulfur battery positive electrode and a sulfur battery comprising same. The polymeric binder for a sulfur battery according to one embodiment of the invention is a crosslinked water-soluble polymeric binder characterized by being prepared through a chemical reaction between a water-soluble polymer and a carboxylic acid-based crosslinking agent.

IPC Classes  ?

• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• H01M 4/136 - Electrodes based on inorganic compounds other than oxides or hydroxides, e.g. sulfides, selenides, tellurides, halogenides or LiCoFy
• H01M 4/38 - Selection of substances as active materials, active masses, active liquids of elements or alloys
• H01M 10/052 - Li-accumulators
• H01M 10/054 - Accumulators with insertion or intercalation of metals other than lithium, e.g. with magnesium or aluminium
• H01M 4/13 - Electrodes for accumulators with non-aqueous electrolyte, e.g. for lithium-accumulatorsProcesses of manufacture thereof
• H01M 4/139 - Processes of manufacture
• H01M 4/02 - Electrodes composed of, or comprising, active material

Abstract

The present invention relates to an ink composition for an electron transport layer, which comprises a core-shell-structured metal oxide surface-treated with a ligand compound and, more specifically, to an ink composition for an electron transport layer, which comprises: a core-shell-structured metal oxide surface treated with a ligand compound; and a solvent. The present invention can provide an ink composition for an electron transport layer, capable of enhancing quantum efficiency, brightness, optical characteristics, device performance, and the like, by modifying the surface of core-shell-structured metal oxide nanoparticles to ensure excellent dispersion stability in the solvent and processability and reduce surface defects of the nanoparticles.

IPC Classes  ?

• C09D 11/037 - Printing inks characterised by features other than the chemical nature of the binder characterised by the pigment
• C09D 11/033 - Printing inks characterised by features other than the chemical nature of the binder characterised by the solvent
• C09K 11/02 - Use of particular materials as binders, particle coatings or suspension media therefor
• C09K 11/56 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing inorganic luminescent materials containing sulfur
• H10K 50/16 - Electron transporting layers
• H10K 50/115 - OLEDs or polymer light-emitting diodes [PLED] characterised by the electroluminescent [EL] layers comprising active inorganic nanostructures, e.g. luminescent quantum dots
• B82Y 40/00 - Manufacture or treatment of nanostructures

Abstract

A vibration measurement error determination method according to an embodiment of the present invention comprises: a vibration data acquisition step for acquiring vibration data by measuring a vibration generated in a structure; a first determination step for determining, on the basis of a preset error data selection rule, whether the vibration data is data generated by a measurement error; a second determination step for using a machine-learning algorithm to determine whether the vibration data is data generated by a measurement error; and a final determination step for determining, on the basis of the results determined in the first determination step and the second determination step, whether the vibration data is data generated by a measurement error.

IPC Classes  ?

• G01H 1/00 - Measuring vibrations in solids by using direct conduction to the detector

Abstract

Disclosed is a communication system using a low-reliability network protocol, the communication system being configured to: identify whether at least one first packet from among a plurality of first packets has been received from a transmission device; and transmit, to the transmission device, a second packet including a not acknowledgment (NACK) signal, on the basis of whether the reception is identified, wherein the second packet includes designated header data, the specified header data includes at least one field from among a first field, a second field and a third field, the first field indicates whether any one first packet from among the plurality of first packets has been received from the transmission device, the second field indicates an increased value or a maintained value according to the any one first packet not received from the transmission device, and the third field indicates an increased value according to another first packet, from among the plurality of first packets, received from the transmission device. Other various embodiments identified through the present document are possible.

IPC Classes  ?

• H04L 1/16 - Arrangements for detecting or preventing errors in the information received by using return channel in which the return channel carries supervisory signals, e.g. repetition request signals
• H04L 1/00 - Arrangements for detecting or preventing errors in the information received

Abstract

The present invention relates to a punching-type iridotomy instrument, and more particularly, to a punching-type iridotomy instrument which, in iridectomy, increases the size and positioning accuracy iris incision through structural improvement in a perforation method, thereby shortening the surgery time and facilitating the convenience of surgical procedures. According to the present invention, the punching-type iridotomy instrument includes a grip manipulation part configured to be manipulated to be opened or closed by a user while being held by the user's hand, an extension shaft extending from the grip manipulation part, and a punching operating unit extending from the extension shaft and configured to perform an operation of forming a hole in a predetermined site of a peripheral portion of an iris in conjunction with an operation of the grip manipulation part performed by the user's manipulation, in which the grip manipulation part includes a first round shaft extending from a rear side of the extension shaft and having a first finger grip ring formed at an end of the first round shaft and configured to be fitted with the user's thumb, a second round shaft hingedly coupled to a predetermined position on the extension shaft by a pivot pin and having a second finger grip ring formed at an end of the second round shaft and configured to be fitted with the user's ring finger, the second round shaft being configured to implement a rotational operation related to a motion of the ring finger fitted into the second finger grip ring, a spring disposed between the first and second round shafts and configured to exert elasticity for pushing the second round shaft, and a wire configured to connect the second round shaft and the punching operating unit while passing through the extension shaft and operate the punching operating unit in conjunction with a rotational operation of the second round shaft.

IPC Classes  ?

• A61F 9/007 - Methods or devices for eye surgery

Abstract

The present invention is based on discovering the effects that treatment with Lonicera japonica extract have on cell survival rate, the inhibition of oxidative stress generation, inflammation and cell death biomarkers, antioxidant activity, improvements in mitochondrial function, changes in immune cell count, changes in immune substance levels, alterations in inflammation-related protein expression, pulmonary fibrosis markers, and the expression of matrix metalloproteinases (MMPs). Thus, it was found that the Lonicera japonica extract could be used as a composition for preventing or treating respiratory diseases.

IPC Classes  ?

• A61K 36/355 - Lonicera (honeysuckle)
• A61P 11/00 - Drugs for disorders of the respiratory system
• A61P 39/06 - Free radical scavengers or antioxidants
• A61P 43/00 - Drugs for specific purposes, not provided for in groups
• A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
• A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
• A23L 2/38 - Other non-alcoholic beverages

Abstract

The objective of the present invention is to provide a compound having a novel structure, and a preparation method therefor, the compound being effectively usable as an electron acceptor material of an organic solar cell. Particularly, the compound according to the present invention implements an electron affinity similar to that of a fullerene derivative and, simultaneously, has a high absorption coefficient for sunlight, and has an excellent miscibility with a known electron donor polymer material that is generally used, and thus can provide a high-performance organic solar cell.

IPC Classes  ?

• C07D 513/22 - Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups , or in which the condensed system contains four or more hetero rings
• H10K 85/60 - Organic compounds having low molecular weight

Abstract

The present invention relates to a system for quantifying lung disease of a lung sample, and a method for quantifying lung disease by using the same, and, more particularly, to a system for quantifying lung disease of a lung sample by using computer vision and machine learning, and a method for quantifying lung disease by using same, the system detecting pneumonia and emphysematous lesions from an image of a lung sample and using same to identify pneumonia incidence and emphysema incidence, thereby enabling standard quantification of expert opinions.

IPC Classes  ?

• G16H 50/50 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for simulation or modelling of medical disorders
• G16H 30/00 - ICT specially adapted for the handling or processing of medical images
• A61B 10/02 - Instruments for taking cell samples or for biopsy
• G06V 20/69 - Microscopic objects, e.g. biological cells or cellular parts
• G06V 10/46 - Descriptors for shape, contour or point-related descriptors, e.g. scale invariant feature transform [SIFT] or bags of words [BoW]Salient regional features
• G06V 10/26 - Segmentation of patterns in the image fieldCutting or merging of image elements to establish the pattern region, e.g. clustering-based techniquesDetection of occlusion

Abstract

The present invention relates to a method for providing augmented reality on a miniature diorama and, more specifically, to a method by which: when at least one information acquisition device installed in a specific real world environment acquires real-time reality information, a virtual content system identifies and recognizes an object included in the real-time reality information; virtual content is created on the basis of the recognized object; and, when a user photographs a miniature diorama by means of a user terminal, the virtual content is augmented and displayed on a screen of the user terminal, or when the miniature diorama is photographed by means of the user terminal, a virtual object related to the photographed miniature diorama and a virtual object related to a specific location are augmented and provided on the screen of the user terminal.

IPC Classes  ?

• G06Q 50/10 - Services
• G06T 19/00 - Manipulating 3D models or images for computer graphics
• G06T 13/40 - 3D [Three Dimensional] animation of characters, e.g. humans, animals or virtual beings
• H04N 21/81 - Monomedia components thereof
• H04N 21/43 - Processing of content or additional data, e.g. demultiplexing additional data from a digital video streamElementary client operations, e.g. monitoring of home network or synchronizing decoder's clockClient middleware
• G06T 7/70 - Determining position or orientation of objects or cameras
• G06F 3/01 - Input arrangements or combined input and output arrangements for interaction between user and computer
• G06F 3/16 - Sound inputSound output
• H04N 13/332 - Displays for viewing with the aid of special glasses or head-mounted displays [HMD]
• G02B 27/01 - Head-up displays

Abstract

The present invention relates to a nucleic acid molecule for the expression of multiple proteins, wherein a plurality of protein expression constructs is structured into a single entity through the hybridization reaction of additional sequences bound to each end thereof. The present invention enables the simultaneous and equimolar expression of a plurality of target proteins with efficiency within a single host cell through the simple design of attaching an arbitrary additional sequence to the 3' end of each expression construct, the arbitrary additional sequence being designed for either direct hybridization therebetween or simultaneous hybridization to the same linker molecule. The present invention can be particularly useful as an efficient multiple expression system overcoming the drawbacks of conventional self-cleaving peptide expression systems that exhibit uneven expression patterns among different proteins.

IPC Classes  ?

• C12N 15/11 - DNA or RNA fragmentsModified forms thereof
• C12N 15/66 - General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligationUse of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease

Abstract

In an embodiment, an ionomer includes a partial structure represented by: In an embodiment, an ionomer includes a partial structure represented by: In an embodiment, an ionomer includes a partial structure represented by: wherein z is an integer of 1 to 10.

IPC Classes  ?

• C08F 293/00 - Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
• H01M 4/90 - Selection of catalytic material
• H01M 8/1032 - Polymeric electrolyte materials characterised by the chemical structure of the main chain of the ion-conducting polymer having sulfur, e.g. sulfonated-polyethersulfones [S-PES]
• H01M 8/1039 - Polymeric electrolyte materials halogenated, e.g. sulfonated polyvinylidene fluorides

Abstract

The present invention relates to a fluorene-based branched copolymer polymer electrolyte membrane and a water electrolysis system. The present invention comprises fluorine, which is stable with respect to radicals, and has an entire polymer main chain composed of only C-C bonds, and thus has excellent chemical stability.

IPC Classes  ?

• C08G 61/02 - Macromolecular compounds containing only carbon atoms in the main chain of the macromolecule, e.g. polyxylylenes
• C08J 5/22 - Films, membranes or diaphragms

Abstract

Provided is a cathode for a sodium/sulfur (NaS) battery. The cathode includes polysodium-sulfide polyacrylonitrile (NaxS-PAN, 3≤x) obtained by reaction with a large amount of sodium, and is a high-capacity electrode manufactured via sodiation to inject sodium.

IPC Classes  ?

• H01M 4/60 - Selection of substances as active materials, active masses, active liquids of organic compounds
• H01M 4/02 - Electrodes composed of, or comprising, active material
• H01M 4/38 - Selection of substances as active materials, active masses, active liquids of elements or alloys
• H01M 10/054 - Accumulators with insertion or intercalation of metals other than lithium, e.g. with magnesium or aluminium
• H01M 50/609 - Arrangements or processes for filling with liquid, e.g. electrolytes

Abstract

The present invention relates to: an electrode (positive electrode) having a high loading amount due to having a structure in which pores in a carbon fiber constituting a three-dimensional porous carbon current collector are filled with sulfur (S) and the exterior (surface) of the carbon current collector is firmly covered with a conductive material and a binder (polymer), wherein the electrical conductivity of sulfur, which is an insulator, is increased; a battery using same; and a method of producing same.

IPC Classes  ?

• H01M 4/13 - Electrodes for accumulators with non-aqueous electrolyte, e.g. for lithium-accumulatorsProcesses of manufacture thereof
• H01M 4/66 - Selection of materials
• H01M 4/38 - Selection of substances as active materials, active masses, active liquids of elements or alloys
• H01M 4/80 - Porous plates, e.g. sintered carriers
• H01M 4/62 - Selection of inactive substances as ingredients for active masses, e.g. binders, fillers
• H01M 4/139 - Processes of manufacture
• H01M 4/02 - Electrodes composed of, or comprising, active material

Abstract

Provided is a composition and a fructose production method, wherein the composition contains: sucrose phosphorylase or a microorganism expressing same; or a culture or lysate of the microorganism whereby fructose can be produced at low cost with high yield.

IPC Classes  ?

• C12P 19/18 - Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
• C12N 9/10 - Transferases (2.)
• C12P 19/02 - Monosaccharides

Abstract

A composition includes tyrosine-amino acid peptide as effective component. The composition may enhance umami. The amino acid may be lysine, methionine, valine, serine, cysteine, arginine, asparagine, aspartic acid, alanine, isoleucine, leucine, threonine, tyrosine, glutamine, glutamic acid, glycine, histidine, phenylalanine, proline, or tryptophan. The composition may further includes glutamine. The composition may be added to food to enhance umami.

IPC Classes  ?

• A23L 27/21 - Synthetic spices, flavouring agents or condiments containing amino acids

Abstract

A shearing process simulation method may include a first step in which a finite element and a node are generated in a raw material, a second step in which a fracture surface is calculated for a sheared material with a shearing force applied to the raw material, a third step in which an element of the sheared material is divided into a first group and a second group with the fracture surface as a boundary, a fourth step in which an average value is obtained by averaging information of a second group element or a second group node included in the second group, and a fifth step in which a final fracture surface is generated by reflecting the average value in the fracture surface.

IPC Classes  ?

• G06F 30/23 - Design optimisation, verification or simulation using finite element methods [FEM] or finite difference methods [FDM]
• G06T 17/20 - Wire-frame description, e.g. polygonalisation or tessellation

Abstract

The present invention relates to a flexible electrode material and a preparation method therefor. An aspect of the present invention provides a flexible electrode material comprising a graphene film and a free-standing metal oxide formed on the graphene film.

IPC Classes  ?

• H01M 4/50 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese
• H01M 4/04 - Processes of manufacture in general
• H01M 4/66 - Selection of materials
• H01M 10/36 - Accumulators not provided for in groups

Abstract

A method for manufacturing a semiconductor device is disclosed. The manufacturing method comprises the steps of: preparing a substrate on which a unit cell is formed, forming a mask for forming a passing word-line, on the substrate; performing primary etching to form a vertical trench deeper than the lower end of the unit cell on the substrate having the mask formed thereon; performing secondary etching to have an overhang structure on a lower end region of the vertical trench; forming an insulating layer on the trench having the overhang structure; and filling, with a conductive material, the trench having the insulating layer formed thereon, to form a passing word-line (PWL).

IPC Classes  ?

• H10B 12/00 - Dynamic random access memory [DRAM] devices

Abstract

The present invention relates to a flow quantification method for a drilling flow, and a viscosity monitoring technique using same, and to a flow quantification method for a drilling flow in an annular pipe which enables a fluid to flow by means of a pressure difference between an entrance and an exit thereof, and enables the generation of a rotational flow by means of a rotational motion thereof, and a viscosity monitoring technique using same, the present invention comprising: a flow state measurement step for measuring the pressure, flow rate of an entrance and an exit of an annular pipe, and the total torque, number of rotations, pressure drop and flow rate of the annular pipe; an energy dissipation rate calculation step for calculating an energy dissipation rate according to the flow state measured in the flow state measurement step; and a viscous behavior calculation step for calculating an effective shear rate on the basis of the energy dissipation rate, and calculating viscous behavior of a fluid in the annular pipe by means of the effective shear rate. In addition, the viscous behavior calculation step enables the measurement of viscous behavior in a drilling flow in the annular pipe, the drilling flow having a rotational flow and a pressure differential flow occurring in a complex manner. In addition, according to the present invention, the effect is achieved of enabling the calculation and monitoring of the viscous behavior, pressure drop, flow rate and torque of mud which is drilling-flowing in the annular pipe. In addition, the present invention has the effect of enabling the viscosity of mud to be accurately measured even when eccentricity occurs as a result of a bending of the annular pipe.

IPC Classes  ?

• G01N 11/14 - Investigating flow properties of materials, e.g. viscosity or plasticityAnalysing materials by determining flow properties by moving a body within the material by using rotary bodies, e.g. vane
• G01D 21/02 - Measuring two or more variables by means not covered by a single other subclass
• G01N 11/00 - Investigating flow properties of materials, e.g. viscosity or plasticityAnalysing materials by determining flow properties

Abstract

The present invention relates to a sulfur-triazine polymer and a lithium-sulfur battery that contains same as a positive electrode and thus can be used in a lean electrolyte, and, more particularly, to a sulfur-triazine polymer prepared by covalently grafting sulfur to triazine, and a lithium-sulfur battery that contains same in the positive electrode and thus exhibits high performance even in a lean electrolyte.

IPC Classes  ?

• C08G 73/06 - Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromoleculePolyhydrazidesPolyamide acids or similar polyimide precursors
• H01M 4/137 - Electrodes based on electro-active polymers
• H01M 10/052 - Li-accumulators
• H01M 4/02 - Electrodes composed of, or comprising, active material

Abstract

The present invention relates to a polymer electrolyte membrane of a fluorene- and biphenyl-based branched copolymer having condensed aliphatic sulfonic acid groups and a water electrolysis system using same and, specifically, to a polymer-based electrolyte membrane of a random/branched copolymer, which attains outstanding hydrogen ion conductivity and mechanical properties in a hydrocarbon-based proton exchange electrolyte membrane, can increase performance thereof, such as oxidation stability, and can also be utilized as an electrolyte membrane for water electrolysis using a polymer electrolyte membrane operated under high-temperature/pressurization conditions.

IPC Classes  ?

• C08J 5/22 - Films, membranes or diaphragms
• C08G 61/02 - Macromolecular compounds containing only carbon atoms in the main chain of the macromolecule, e.g. polyxylylenes
• C25B 13/08 - DiaphragmsSpacing elements characterised by the material based on organic materials
• C25B 1/04 - Hydrogen or oxygen by electrolysis of water
• C25B 9/19 - Cells comprising dimensionally-stable non-movable electrodesAssemblies of constructional parts thereof with diaphragms
• H01M 8/1039 - Polymeric electrolyte materials halogenated, e.g. sulfonated polyvinylidene fluorides

Abstract

Copine1Copine1Copine1Copine1 gene, and a pharmaceutical composition for inhibiting the metastasis of HER2-positive breast cancer, comprising a Copine1 protein expression inhibitor as an active ingredient.

IPC Classes  ?

• C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
• G01N 33/574 - ImmunoassayBiospecific binding assayMaterials therefor for cancer
• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
• A61P 35/00 - Antineoplastic agents

Abstract

The present invention relates to a method for controlling the surface characteristics and thickness of a multilayer transition metal dichalcogenide thin film. By forming an amorphous transition metal oxide thin film on a multilayer transition metal dichalcogenide thin film, and then treating the multilayer transition metal dichalcogenide thin film having the amorphous transition metal oxide thin film formed thereon with an aqueous solution of ammonium sulfide at least once, the surface characteristics and thickness of the transition metal dichalcogenide can be controlled in a simple and low-cost manner without complex equipment settings for heat treatment, plasma and laser etching, and so on.

IPC Classes  ?

• H01L 21/02 - Manufacture or treatment of semiconductor devices or of parts thereof

Abstract

The present invention relates to a composition containing osmotin protein as an active ingredient for the prevention, alleviation, or treatment of Parkinson's disease. The osmotin protein has the effects of: alleviating behavioral and motor deficiencies induced by MPTP/α-synuclein; protecting dopamine-active neurons; regulating the expression of neuroinflammation-related proteins; suppressing MPTP/α-synuclein-induced cell death; mitigating cellular damage from the overexpression of α-synuclein (A53T); activating AMPK, and subsequently reducing the accumulation of α-synuclein through autophagy; modulating the dendritic composite structure; increasing spine density in pyramidal neurons; alleviating cognitive deficits; and restoring the expression of synaptic markers. Hence, the composition can be beneficially used as a health functional food or medicine for the prevention, improvement, or treatment of Parkinson's disease.

IPC Classes  ?

• A23L 33/18 - PeptidesProtein hydrolysates
• A23L 33/175 - Amino acids
• A61K 38/16 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
• A61P 25/16 - Anti-Parkinson drugs
• A23L 2/38 - Other non-alcoholic beverages
• A23P 10/28 - TablettingMaking food bars by compression of a dry powdered mixture
• A23P 10/30 - Encapsulation of particles, e.g. foodstuff additives

Abstract

A peptide with terminal tyrosine has an excellent effect on inhibiting protein nitration and also an excellent effect on preventing, ameliorating, or treating disease symptoms in chronic immobilization stress-induced depression/cognitive impairment model, Alzheimer's disease model, epileptic seizure model, stroke model, type 2 diabetes model, acute renal failure model, or hyperammonemia model.

IPC Classes  ?

• A61K 38/05 - Dipeptides
• A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
• A61P 25/24 - Antidepressants
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• A61P 25/08 - AntiepilepticsAnticonvulsants
• A61P 3/10 - Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
• A61P 13/12 - Drugs for disorders of the urinary system of the kidneys
• A61K 9/00 - Medicinal preparations characterised by special physical form

Abstract

The present invention relates to a polymer hydrogel including fulvic acid and minoxidil, a composition containing same as an active ingredient for promoting hair regrowth, and a manufacturing method therefor. According to an embodiment of the present invention, the polymer hydrogel includes minoxidil and a fulvic acid-bearing polymer that contains minoxidil and simultaneously releases minoxidil and fulvic acid in a sustained manner.

IPC Classes  ?

• A61K 8/11 - Encapsulated compositions
• A61K 8/96 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution
• A61K 8/49 - Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
• A61K 8/73 - Polysaccharides
• A61Q 7/00 - Preparations for affecting hair growth

Abstract

The present invention relates to a branched copolymer proton exchange membrane comprising a Nafion-grafted graphene oxide, and a water electrolysis system using same. The present invention provides excellent chemical stability due to comprising fluorene, which is stable to radicals, and having a polymer main chain entirely consisting only of C-C bonds, and the manufactured composite membrane has improved hydrogen ion conductivity by comprising a modified graphene oxide.

IPC Classes  ?

• C08J 5/22 - Films, membranes or diaphragms
• C08L 27/22 - Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a halogenCompositions of derivatives of such polymers modified by chemical after-treatment
• C08L 51/10 - Compositions of graft polymers in which the grafted component is obtained by reactions only involving carbon-to-carbon unsaturated bondsCompositions of derivatives of such polymers grafted on to inorganic materials
• C08G 61/02 - Macromolecular compounds containing only carbon atoms in the main chain of the macromolecule, e.g. polyxylylenes
• C08F 292/00 - Macromolecular compounds obtained by polymerising monomers on to inorganic materials
• C25B 13/08 - DiaphragmsSpacing elements characterised by the material based on organic materials
• C25B 1/04 - Hydrogen or oxygen by electrolysis of water

Abstract

The present invention relates to a thermoplastic vulcanizate which has increased biomass content by using an environmentally-friendly material as an alternative to conventional petroleum-based materials, and thus may prevent various kinds of environmental pollution, etc., and also enables the improvement of mechanical properties such as tensile strength, hardness, thermal stability, etc., and thus may be applied in a wide range of fields as an alternative to existing thermoplastic vulcanizates.

IPC Classes  ?

• C08L 23/12 - Polypropene
• C08L 21/00 - Compositions of unspecified rubbers
• C08K 5/14 - Peroxides

Abstract

The present invention relates to a bio-based plastic composite comprising bio-based polypropylene, a manufacturing method therefor, and uses of the bio-based plastic composite manufactured therefrom. By significantly improving the environmental pollution prevention function and facilitating improvements in mechanical properties, such as tensile strength, flexural modulus, and melt index, the present invention can be applied to a wide range of fields as a replacement for existing plastic products.

IPC Classes  ?

• C08L 23/12 - Polypropene
• C08L 1/02 - CelluloseModified cellulose
• C08K 3/34 - Silicon-containing compounds
• C08K 3/26 - CarbonatesBicarbonates

Abstract

The present invention relates to a composition for inflammation inhibition and immunoregulation of degenerative brain diseases, comprising an Syk inhibitor as an active ingredient. The Syk inhibitor, specifically, BAY61-3606, has the effects of: significantly reducing the expression of Syk, Iba-1, inflammatory cytokines (TNF-α, IL-1α and IL-6) and inflammation-related factors (NF-κB, Cox-2 and iNOS), all of which are up-regulated by LPS; significantly inhibiting microglia-mediated neuronal cell death by regulating the expression of cytochrome C and BCL-2 interacting mediator of cell death (Bim) in LPS-treated mouse brains and HT22 cells; restoring the expression of synaptic markers of synaptosomal-associated protein, 25 kDa (SNAP25), synaptophysin (Syp), and postsynaptic density protein-95 (PSD95) in LPS-treated mouse brains and HT22 cells; and inhibiting cognitive and memory dysfunctions caused by LPS in Y-maze tests and passive avoidance tests, which are related to memory and cognitive dysfunctions, and thus the composition of the present invention, comprising an Syk inhibitor as an active ingredient, can be effectively used for the prevention, alleviation or treatment of degenerative brain diseases.

IPC Classes  ?

• A61K 31/519 - PyrimidinesHydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• A23L 33/10 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives
• A23K 20/137 - Heterocyclic compounds containing two hetero atoms, of which at least one is nitrogen

Abstract

The present invention relates to a method for controlling the size of a metal-organic framework. More specifically, the present invention provides: a method for controlling the size of a metal-organic framework, the method comprising a step for producing an emulsion by mixing an aqueous solvent and a volatile organic compound, a step for producing a suspension by introducing the produced emulsion and a metal precursor into an aqueous solution that contains an organic ligand precursor, and stirring, and a step for centrifuging the produced suspension and dispersing same in an organic solvent after removing the supernatant, and thereby obtaining a metal-organic framework with a controlled size; and a metal-organic framework controlled in size thereby. The method for controlling the size of a metal-organic framework according to the present invention can solve problems associated with existing size control methods, and makes it possible to variously adjust the size of the metal-organic framework through a simple and straightforward process.

IPC Classes  ?

• C07F 3/06 - Zinc compounds

Abstract

A deep learning model training method, a method for diagnosing an ophthalmologic disease by using a deep learning model, and a computer-readable recording medium having recorded thereon a program for performing same comprise: a deep learning model training step in which at least one processor trains a deep learning model by using a plurality of data sets for a plurality of optical coherence tomography (OCT) images acquired through OCT performed on an eyeball; an image acquisition step in which the at least one processor acquires a plurality of OCT images of a testee; and an ophthalmologic disease diagnosing step in which the at least one processor outputs a probability of an ophthalmologic disease or a probability of being normal as a diagnosis result by inputting the plurality of OCT images of the testee to the deep learning model.

IPC Classes  ?

• G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
• G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
• G16H 50/70 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for mining of medical data, e.g. analysing previous cases of other patients
• G06N 3/08 - Learning methods
• A61B 3/14 - Arrangements specially adapted for eye photography

Abstract

in vivoin vitroin vitro.

IPC Classes  ?

• C12N 15/11 - DNA or RNA fragmentsModified forms thereof

Abstract

There is provided a ferritic lightweight steel which contains 2.0 to 3.0 wt % manganese (Mn), 5.0 to 6.0 wt % aluminum (Al) and 0.1 to 0.3 wt % carbon (C) and has a tensile strength of 900 MPa to 1,108 MPa. The lightweight steel includes ferrite-austenite dual grains as a result of performing low-temperature tempering-induced partitioning (LTP) at 300° C. for 10 minutes after isothermal annealing.

IPC Classes  ?

• C22C 38/06 - Ferrous alloys, e.g. steel alloys containing aluminium
• C21D 8/02 - Modifying the physical properties by deformation combined with, or followed by, heat treatment during manufacturing of plates or strips
• C22C 38/04 - Ferrous alloys, e.g. steel alloys containing manganese

Abstract

A deep learning-based lens simulation method and a system therefor are provided. The lens simulation method according to several embodiments of the present disclosure acquires a deep learning model constructed to predict optical characteristic values of a lens from an input pattern image, predicts, through the acquired deep learning model, optical characteristic values of a target lens from a pattern image associated with the target lens, and uses the predicted optical characteristic values so as to accurately simulate a visual field seen through the target lens.

IPC Classes  ?

• G06F 30/27 - Design optimisation, verification or simulation using machine learning, e.g. artificial intelligence, neural networks, support vector machines [SVM] or training a model
• G02C 11/00 - Non-optical adjunctsAttachment thereof
• G06N 3/08 - Learning methods
• G06N 3/04 - Architecture, e.g. interconnection topology

Abstract

The present invention relates to a method for separating beta-mangostin with high purity and high-efficiency by using a simulated moving bend (SMB) process and use thereof, wherein the use of a beta-SMB process and a post-treatment process in the present invention enables the collection of high-purity beta-mangostin and allows a continuous process compared with general batch chromatography, thereby improving the productivity of beta-mangostin.

IPC Classes  ?

• C07D 311/86 - Oxygen atoms, e.g. xanthones

Abstract

The present invention relates to a novel heterocyclic compound and an organic light-emitting device comprising same. More specifically, the present invention relates to a heterocyclic compound which exhibits thermally activated delayed fluorescence (TADF), and an organic light-emitting device comprising same.

IPC Classes  ?

• C07F 5/02 - Boron compounds
• H10K 85/30 - Coordination compounds
• H10K 50/12 - OLEDs or polymer light-emitting diodes [PLED] characterised by the electroluminescent [EL] layers comprising dopants

Abstract

A transgenic plant having cold resistance overexpressing thioredoxin Trx-h2 protein. More specifically, the present invention relates to a transgenic plant having cold resistance overexpressing thioredoxin Trx-h2 protein which is an interacting partner of cold-responsive C-repeat-binding transcription factors (CBF 1).

IPC Classes  ?

• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• C07K 14/415 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from plants

Abstract

The present invention provides a device for diagnosing particles in an opaque fluid, the device comprising: a flowcell through which an opaque fluid having particles mixed therein flows; a lighting unit which comprises a plurality of light sources spaced apart from each other and arranged to irradiate the fluid in the flowcell with infrared rays; a camera which captures an image of the opaque fluid in the flowcell; and an image processing unit which extracts the size and shape of the particles in the opaque fluid through the image captured by the camera, wherein image capture of the particles in the opaque fluid by the camera is performed while changing the irradiation position of infrared rays by controlling the light emission positions of the plurality of light sources when the lighting unit irradiates the infrared rays.

IPC Classes  ?

• G01N 15/02 - Investigating particle size or size distribution
• G01N 15/14 - Optical investigation techniques, e.g. flow cytometry
• G01N 21/35 - Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
• G01N 21/85 - Investigating moving fluids or granular solids
• G01N 15/00 - Investigating characteristics of particlesInvestigating permeability, pore-volume or surface-area of porous materials
• G01N 21/17 - Systems in which incident light is modified in accordance with the properties of the material investigated

Abstract

The present invention relates to a composition for boosting immunity and preventing, ameliorating, and treating Parkinson's disease, the composition comprising O-cyclic phytosphingosine-1-phosphate (cPS1P) derivative as an active ingredient. More specifically, administration of cPS1P of the present invention significantly increased motor function of an animal model of Parkinson's disease, and in an MPTP-induced mouse and an NSE-hαSyn transgenic mouse, administration of cPS1P not only significantly increased the expression of the S1P1 receptor (S1PR1), but also significantly decreased the expression of αSyn. In addition, since there is an effect of a decrease in expression levels of inflammatory cytokines, which have increased in glial cells of an MPTP-induced mouse and an NSE-hαSyn transgenic mouse, by administration of cPS1P of the present invention, the active ingredient of the present invention can be used as a medicine for Parkinson's disease.

IPC Classes  ?

• A61K 31/685 - Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
• A61P 37/02 - Immunomodulators
• A61P 25/16 - Anti-Parkinson drugs
• A23L 33/10 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives
• A23K 20/105 - Aliphatic or alicyclic compounds

Abstract

The present invention relates to a current collector for a zinc-ion battery, a manufacturing method therefor, and a zinc-ion battery. A current collector for a zinc-ion battery according to an embodiment of the present invention comprises: a graphene film; and heteroatoms doped in the graphene film.

IPC Classes  ?

• H01M 4/66 - Selection of materials
• H01M 4/42 - Alloys based on zinc
• H01M 4/50 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese
• H01M 10/36 - Accumulators not provided for in groups

Abstract

333, and a sodium secondary battery separator, coated with the dispersion prepared thereby, having improved electrode performance.

IPC Classes  ?

• H01M 50/431 - Inorganic material
• H01M 50/403 - Manufacturing processes of separators, membranes or diaphragms
• H01M 50/449 - Separators, membranes or diaphragms characterised by the material having a layered structure
• H01M 10/054 - Accumulators with insertion or intercalation of metals other than lithium, e.g. with magnesium or aluminium

Abstract

The present invention provides a marker composition for selecting a living modified organism, which allows transformation and the production of a target product without antibiotics or antibiotic resistance genes, a living modified organism, a method of transforming an organism, and a method of producing a target product. The present invention provides a marker composition for selecting a living modified organism, which may basically prevent problems caused by the use of antibiotics and antibiotic resistance genes and produce a target product at a high yield, a living modified organism, a method of transforming an organism, and a method of producing a target product.

IPC Classes  ?

• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C12N 1/20 - BacteriaCulture media therefor
• C12N 15/74 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
• C12P 5/00 - Preparation of hydrocarbons
• C12P 7/02 - Preparation of oxygen-containing organic compounds containing a hydroxy group
• C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression

Abstract

The present invention relates to a supercapacitor electrode material, and a method for manufacturing same. One aspect of the present invention provides a supercapacitor electrode material including: a carbon material; and phosphorus (p) and boron (b) doped into the carbon material.

IPC Classes  ?

• H01G 11/04 - Hybrid capacitors
• H01G 11/36 - Nanostructures, e.g. nanofibres, nanotubes or fullerenes
• H01G 11/86 - Processes for the manufacture of hybrid or EDL capacitors, or components thereof specially adapted for electrodes

Abstract

This isotope separation method uses a flexible metal organic framework (FMOF) capable of selectively separating/collecting isotopes by means of the kinetic quantum sieve (KQS) effect, and thus can selectively separate a specific isotope from a mixture of isotopes under specific conditions. This separation effect can be attributed to the difference in diffusion rate between isotopes in the pores of a porous material. The difference in diffusion rate between isotopes in the present invention can be determined by a quasi-elastic neutron scattering (QENS) experiment for microscopic observation of isotopic molecular transport during the breathing transition (BT) of pores (100). It can be determined through QENS that deuterium diffuses faster than hydrogen in the pores (100), and the difference in diffusion rate between isotopes may increase with increasing temperature. The present invention can be applied to an adsorbent capable of separating isotopes using the KQS effect even at a high temperature of 77K or higher.

IPC Classes  ?

• B01D 59/26 - Separation by extracting by sorption, i.e. absorption, adsorption, persorption
• G21F 9/12 - Processing by absorptionProcessing by adsorptionProcessing by ion-exchange
• B01J 20/22 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising organic material

Abstract

A method for ameliorating or treating brain damage and mild cognitive impairment includes administering a composition including glutamine or a salt thereof as effective component to a subject in need thereof. Glutamine as the effective component not only can restore the memory and cognitive ability impaired by stress but also can suppress a damage on nerve cells, reduce the amount of ROS/RNS and other related proteins in brain tissues, and enhance synaptic plasticity. When the animal model of Alzheimer's disease is fed with glutamine, cognitive ability of the animal is improved and accumulation of Aβ42 is suppressed.

IPC Classes  ?

• A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

A compound is represented by Formula 1 below: A compound is represented by Formula 1 below: A compound is represented by Formula 1 below: wherein R1 to R4 are each independently a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, a fluoro-substituted alkyl group having 1 to 6 carbon atoms, or a fluorine atom, wherein at least one among R1 to R4 is a fluorine atom, A is a divalent linking group, M1 and M2 are each independently potassium or sodium, and n and m are each independently an integer of 1 to 10.

IPC Classes  ?

• H01M 8/1032 - Polymeric electrolyte materials characterised by the chemical structure of the main chain of the ion-conducting polymer having sulfur, e.g. sulfonated-polyethersulfones [S-PES]
• C08K 5/41 - Compounds containing sulfur bound to oxygen
• C07C 309/10 - Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing oxygen atoms bound to the carbon skeleton containing etherified hydroxy groups bound to the carbon skeleton with the oxygen atom of at least one of the etherified hydroxy groups further bound to an acyclic carbon atom
• H01M 8/1004 - Fuel cells with solid electrolytes characterised by membrane-electrode assemblies [MEA]
• H01M 8/1027 - Polymeric electrolyte materials characterised by the chemical structure of the main chain of the ion-conducting polymer having carbon, oxygen and other atoms, e.g. sulfonated polyethersulfones [S-PES]
• H01M 8/1039 - Polymeric electrolyte materials halogenated, e.g. sulfonated polyvinylidene fluorides
• H01M 8/1067 - Polymeric electrolyte materials characterised by their physical properties, e.g. porosity, ionic conductivity or thickness

Abstract

o22O) intercalated in the lattice of the oxygen vacancy-containing vanadium oxide nanoparticles.

IPC Classes  ?

• H01M 4/48 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides
• C01G 31/02 - Oxides
• H01M 4/04 - Processes of manufacture in general
• H01M 4/64 - Carriers or collectors
• H01M 10/36 - Accumulators not provided for in groups
• H01M 4/02 - Electrodes composed of, or comprising, active material

Abstract

The present invention relates to a negative electrode material for a zinc-ion capacitor, a manufacturing method therefor, and a zinc-ion capacitor. The negative electrode material for a zinc-ion capacitor, according to an embodiment of the present invention, comprises embossed and punched zinc (Zn), wherein the embossed zinc has a plurality of irregularities having a cross-section in a convex shape, a concave shape, or both the shapes, and the punched zinc has macropores formed therein.

IPC Classes  ?

• H01G 11/26 - Electrodes characterised by their structure, e.g. multi-layered, porosity or surface features
• H01G 11/30 - Electrodes characterised by their material
• H01G 11/54 - Electrolytes
• H01G 11/86 - Processes for the manufacture of hybrid or EDL capacitors, or components thereof specially adapted for electrodes

Abstract

Disclosed is a water supply and drainage facility defect detection system comprising: a defect detection data set storage unit for storing at least one piece of defect prediction data and at least one piece of defect history data that are related to water supply and drainage facilities; an image conversion unit for generating at least one piece of prediction image data on the basis of 3D model data corresponding to the at least one piece of defect prediction data; a neural network generation unit for associating the at least one piece of prediction image data with the at least one piece of defect history data and performing machine learning therewith; and a defect detection module for determining whether a defect is included in real-time image data acquired from the water supply and drainage facilities. Other various embodiments identified through the present document are possible.

IPC Classes  ?

• G01N 21/88 - Investigating the presence of flaws, defects or contamination
• G01N 21/954 - Inspecting the inner surface of hollow bodies, e.g. bores
• G06T 7/00 - Image analysis
• G06T 7/11 - Region-based segmentation
• G06T 17/30 - Surface description, e.g. polynomial surface description
• G06N 20/00 - Machine learning

Abstract

The present invention relates to a sandwich structure for absorbing electromagnetic waves in a UHF band. The sandwich structure for absorbing electromagnetic waves in a UHF band, according to an embodiment of the present invention, may comprise: an upper skin; a lower skin; a folded core formed to be in contact with the upper skin and the lower skin; and a filler formed therebetween. Various other embodiments may also be possible.

IPC Classes  ?

• H01Q 17/00 - Devices for absorbing waves radiated from an antenna Combinations of such devices with active antenna elements or systems
• H05K 9/00 - Screening of apparatus or components against electric or magnetic fields

Abstract

The present invention relates to a ginseng root rot prevention composition containing aspartic acid as an active ingredient, a ginseng root rot prevention method using the composition, and a composition for enhancing the growth of beneficial microorganisms in the rhizosphere containing aspartic acid as an active ingredient.

IPC Classes  ?

• A01N 37/44 - Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio-analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio-analogue of a carboxylic group, e.g. amino-carboxylic acids
• C12N 1/20 - BacteriaCulture media therefor
• A01P 3/00 - Fungicides
• A01P 21/00 - Plant growth regulators

Abstract

A gripping device is disclosed. The gripping device comprises: a first finger and a second finger which are arranged to face each other; a first link of which the front end is connected to the rear end of the first finger; a second link of which the front end is connected to the rear end of the second finger; a driving device which rotates the rear end of the first link and the rear end of the second link in different directions so that the first and second fingers are closer to each other or away from each other; tri-axial force sensors which are respectively arranged in the first and second fingers and sense the weight of an object when the first and second fingers grip the object; and a processor controlling the driving device so that the first and second fingers grip the object with the gripping force corresponding to the weight of the object sensed by the tri-axial force sensors.

IPC Classes  ?

• B25J 15/02 - Gripping heads servo-actuated
• B25J 13/08 - Controls for manipulators by means of sensing devices, e.g. viewing or touching devices

Abstract

The present invention relates to a composition for preventing, ameliorating, or treating Alzheimer's disease containing tyrosine as an active ingredient. Since tyrosine, the active ingredient of the present invention, has the effect of enhancing cognitive function and activating glutamatergic signaling, the present invention may be effectively used as a health functional food for preventing or improving cognitive function, or a pharmaceutical product for preventing or treating cognitive function.

IPC Classes  ?

• A23L 33/175 - Amino acids
• A23L 33/10 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives
• A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• A23P 10/20 - AgglomeratingGranulatingTabletting
• A23P 10/28 - TablettingMaking food bars by compression of a dry powdered mixture
• A23P 10/30 - Encapsulation of particles, e.g. foodstuff additives

Abstract

A method for ameliorating a disease caused by nitration of tyrosine in protein includes administering a composition comprising tyrosine or a salt thereof to a subject in need thereof. Tyrosine as effective component of the present invention not only can enhance the activity of glutamine synthetase having reduced activity and but also has an effect of restoring the amount (i.e., ratio) of glutamine and glutamic acid in brain and the amount of ammonia to normal level, an effect of enhancing the insulin sensitivity in a model of type 2 diabetes, an effect of suppressing the excitotoxicity and oxidative stress in a model of epileptic seizure, an effect of reducing cerebral infarction and enhancing the activity of GS in a model of brain stroke, an effect of eliminating the nitration of tyrosine using human recombinant MnSOD, and an effect for acute renal failure and hyperammonemia.

IPC Classes  ?

• A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
• A23L 33/175 - Amino acids
• A61P 13/12 - Drugs for disorders of the urinary system of the kidneys
• A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
• A61P 25/00 - Drugs for disorders of the nervous system
• A61P 3/00 - Drugs for disorders of the metabolism

Abstract

The present invention relates to an electrolyte for a zinc-ion battery and to a zinc-ion battery comprising same. An electrolyte for a zinc-ion battery, according to one embodiment of the present invention, comprises: a zinc electrolyte; and an additive containing a manganese salt.

IPC Classes  ?

• H01M 10/36 - Accumulators not provided for in groups
• H01M 4/50 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides of manganese
• H01M 4/48 - Selection of substances as active materials, active masses, active liquids of inorganic oxides or hydroxides

Abstract

The present invention relates to: a pharmaceutical composition for preventing or treating liver fibrosis induced by non-alcoholic steatohepatitis, containing, as an active ingredient, an expression inhibitor of lipocalin 2 or a receptor thereof; a method for inhibiting the activation of hepatic stellate cells by treatment with the lipocalin 2 receptor inhibitor; and a method for screening for agents for non-alcoholic steatohepatitis-induced liver fibrosis diagnosis and liver fibrosis treatment by using lipocalin 2. The composition containing, as an active ingredient, a lipocalin 2 receptor inhibitor or a lipocalin 2 expression inhibitor, of the present invention, can be used as a therapeutic agent for non-alcoholic steatohepatitis-induced liver fibrosis. The present invention can provide a method for screening for agents for non-alcoholic steatohepatitis-induced liver fibrosis diagnosis and liver fibrosis treatment by using lipocalin 2, and can provide a method for inhibiting the activation of hepatic stellate cells by treatment with a lipocalin 2 receptor inhibitor.

IPC Classes  ?

• A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
• A61K 31/713 - Double-stranded nucleic acids or oligonucleotides
• A61P 43/00 - Drugs for specific purposes, not provided for in groups
• A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
• G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor
• C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

Abstract

Embodiments provide a heterocyclic compound, a light-emitting device that includes the heterocyclic compound, and an electronic apparatus that includes the light-emitting device. The light-emitting device includes a first electrode, a second electrode facing the first electrode, an interlayer between the first electrode and the second electrode and including an emission layer, and at least one of the heterocyclic compound. The heterocyclic compound is represented by Formula 1, which is explained in the specification: Embodiments provide a heterocyclic compound, a light-emitting device that includes the heterocyclic compound, and an electronic apparatus that includes the light-emitting device. The light-emitting device includes a first electrode, a second electrode facing the first electrode, an interlayer between the first electrode and the second electrode and including an emission layer, and at least one of the heterocyclic compound. The heterocyclic compound is represented by Formula 1, which is explained in the specification:

IPC Classes  ?

• H10K 85/60 - Organic compounds having low molecular weight
• C07D 487/16 - Peri-condensed systems
• C09K 11/06 - Luminescent, e.g. electroluminescent, chemiluminescent, materials containing organic luminescent materials

Abstract

An anti-icing honeycomb core composite manufactured by forming an electromagnetic wave absorption layer by using dielectric fiber, molding the electromagnetic wave absorption layer into a honeycomb core structure by using a molded part including a first base, a second base, and an inner block, hardening the honeycomb core structure, and removing the molded part. The molding step includes first stacking, on the first base including a plurality of grooves in which the inner blocks each having a hexagonal column shape are able to be seated, a plurality of the inner blocks and a plurality of the electromagnetic wave absorption layers as the honeycomb core structure so that the electromagnetic wave absorption layer is disposed between the plurality of inner blocks, and second stacking covering the inner blocks and the electromagnetic wave absorption layers stacked on the first base with the second base having the same shape as the first base.

IPC Classes  ?

• B29D 24/00 - Producing articles with hollow walls
• B29B 15/10 - Coating or impregnating
• B29C 70/06 - Fibrous reinforcements only
• B29C 70/88 - Shaping composites, i.e. plastics material comprising reinforcements, fillers or preformed parts, e.g. inserts characterised primarily by possessing specific properties, e.g. electrically conductive or locally reinforced
• B29L 31/30 - Vehicles, e.g. ships or aircraft, or body parts thereof
• B64C 1/00 - FuselagesConstructional features common to fuselages, wings, stabilising surfaces or the like
• B64D 15/20 - Means for detecting icing or initiating de-icing
• C08J 5/08 - Reinforcing macromolecular compounds with loose or coherent fibrous material using pretreated fibrous materials glass fibres
• C08L 63/00 - Compositions of epoxy resinsCompositions of derivatives of epoxy resins

Abstract

Eucommia ulmoidesEucommia ulmoides leaf fraction as an active ingredient for preventing, palliating, or treating brain diseases caused by ultrafine particulate matter. More specifically, a Eucommia ulmoides leaf fraction was verified to have an excellent cytoprotective effect against the cytotoxicity generated in brain nerve cells and identified to be directly preventive, palliative, or therapeutic for brain nerve diseases caused by ultrafine particulate matter through animal experiments, which has led to the present invention. The present invention can be usefully utilized as a health functional food composition for preventing or palliating brain diseases caused by ultrafine particulate matter, as a food composition for preventing or palliating brain diseases caused by ultrafine particulate matter, as a pharmaceutical composition for preventing or treating brain diseases caused by ultrafine particulate matter, or as a cosmetic composition for preventing or palliating brain diseases caused by ultrafine particulate matter.

IPC Classes  ?

• A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
• A61K 36/46 - Eucommiaceae (Eucommia family), e.g. hardy rubber tree
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

Eucommia ulmoidesEucommia ulmoides leaf fraction as an active ingredient and, more specifically, the present invention was completed by confirming that a Eucommia ulmoides leaf fraction has the effects of direct prevention, amelioration, or treatment of bowel diseases caused by ultrafine dust. The present invention can be effectively used as a health functional food composition for preventing or ameliorating bowel diseases caused by ultrafine dust, a food composition for preventing or ameliorating bowel diseases caused by ultrafine dust, a pharmaceutical composition for preventing or treating bowel diseases caused by ultrafine dust, or as a cosmetic composition for preventing or ameliorating bowel diseases caused by ultrafine dust.

IPC Classes  ?

• A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
• A61K 36/46 - Eucommiaceae (Eucommia family), e.g. hardy rubber tree
• A61P 1/00 - Drugs for disorders of the alimentary tract or the digestive system

Abstract

The purpose of the present invention is to provide a composition for prevention or treatment of particulate matter 2.5 (PM2.5)-induced inflammatory disease, comprising a powdered tea extract as an active ingredient, and more specifically, a composition for prevention or treatment of PM2.5-induced respiratory disease, brain and nervous system disease, skin disease, and bowel disease has been accomplished by verifying that a powdered tea extract exhibits an excellent cell protection effect against cytotoxicity occurring in lung cells, brain nerve cells, skin cells, and bowel cells, and inhibits an inflammation-associated protein expression level in the lung, brain, skin, and bowel tissue of an animal model exposed to PM2.5. The present invention may be usefully employed as a pharmaceutical composition for prevention or treatment of PM2.5-induced inflammatory disease, a health functional food composition for prevention and alleviation of PM2.5-induced inflammatory disease, a cosmetic composition for prevention and alleviation of PM2.5-induced inflammatory disease.

IPC Classes  ?

• A61K 36/82 - Theaceae (Tea family), e.g. camellia
• A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
• A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
• A61K 8/9789 - Magnoliopsida [dicotyledons]
• A61Q 19/00 - Preparations for care of the skin

Abstract

The present invention relates to a composition for preventing, ameliorating or treating depression and anxiety disorders caused by chronic stress, the composition comprising a matcha extract as an active ingredient and, more specifically, to a material for inducing tension relief in an animal model exposed to chronic stress. The matcha extract has an excellent effect of ameliorating and treating cranial nerve disorders caused by chronic stress and has the effect of increasing the expression levels of p-CERB, BDNF, and a BDNF protein in hippocampal tissue, and thus can be effectively used in development as a health functional food or medicine for ameliorating or treating depression or anxiety disorders caused by chronic stress.

IPC Classes  ?

• A61K 36/82 - Theaceae (Tea family), e.g. camellia
• A61P 25/24 - Antidepressants
• A61P 25/22 - Anxiolytics
• A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives

Abstract

A light emitting device that includes a first electrode, a second electrode oppositely disposed to the first electrode, and an emission layer between the first electrode and the second electrode is provided. The emission layer includes an organometallic compound represented by Formula 1: A light emitting device that includes a first electrode, a second electrode oppositely disposed to the first electrode, and an emission layer between the first electrode and the second electrode is provided. The emission layer includes an organometallic compound represented by Formula 1:

IPC Classes  ?

• H01L 51/00 - Solid state devices using organic materials as the active part, or using a combination of organic materials with other materials as the active part; Processes or apparatus specially adapted for the manufacture or treatment of such devices, or of parts thereof
• C07F 15/00 - Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table

Abstract

Eucommia ulmoidesEucommia ulmoides leaf fraction as an active ingredient, and more specifically, the present invention has been completed by verifying an excellent cytoprotective effect of the Eucommia ulmoides leaf fraction against cytotoxicity that occurs in pulmonary cells, and by confirming, through animal testing, direct effects thereof in preventing, mitigating, or treating pulmonary diseases caused by ultrafine dust. The present invention may be useful as a nutraceutical composition for preventing or mitigating respiratory diseases caused by ultrafine dust, a pharmaceutical composition for preventing or treating same, or a cosmetic composition for preventing or mitigating same.

IPC Classes  ?

• A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
• A61K 36/46 - Eucommiaceae (Eucommia family), e.g. hardy rubber tree
• A61P 11/00 - Drugs for disorders of the respiratory system

Abstract

According to a wood plastic composite and a manufacturing method therefor of the present invention, wood flour and tannic acid may be included as materials for the wood plastic composite. This tannic acid is a material having excellent miscibility with the wood flour as a base material, and excellent flame retardancy and eco-friendliness, and thus a wood plastic composite having excellent flame retardancy and high ease of manufacture and eco-friendliness can be provided.

IPC Classes  ?

• B27N 3/02 - Manufacture of substantially flat articles, e.g. boards, from particles or fibres from particles
• B27N 3/00 - Manufacture of substantially flat articles, e.g. boards, from particles or fibres
• B27N 1/02 - Mixing the material with binding agent
• B27N 7/00 - After-treatment, e.g. reducing swelling or shrinkage, surfacingProtecting the edges of boards against access of humidity

Abstract

The present invention relates to hair dyeing and, more particularly, to a composition for dyeing hair having a dyeing effect for hair, characterized in that the composition does not only exhibit a temporary dyeing effect on hair by changing the color of the hair immediately upon application to the hair but also exhibits a semi-permanent or permanent effect on the hair as the color change of the hair gradually accumulates when used repeatedly, and the composition does not contain toxic chemicals used in common hair dyes and does not penetrate the skin and is therefore harmless to the human body even when used for a long period of time; and to cosmetics comprising same. The composition for dyeing hair of the present invention comprises a first composition containing tannin and a second composition containing fulvic acid.

IPC Classes  ?

• A61K 8/60 - SugarsDerivatives thereof
• A61K 8/96 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution
• A61K 8/19 - Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
• A61Q 5/10 - Preparations for permanently dyeing the hair
• A61Q 5/06 - Preparations for styling the hair, e.g. by temporary shaping or colouring

Abstract

The present invention relates to a method for manufacturing a titanium alloy and to a titanium alloy. More specifically, the method for manufacturing a titanium alloy of the present invention can stabilize an alloy metal in an elemental state, and can improve mechanical strength and stability of the manufactured titanium alloy to an excellent level by using a binder that is easily debound without causing side reactions with a metal even in a subsequent debinding process. In addition, a binder with low structural distortion caused by temperature-induced stress and high strength can be used to significantly improve shape stability and mechanical strength of the manufactured titanium alloy and a titanium material using same.

IPC Classes  ?

• B22F 3/10 - Sintering only
• B22F 1/107 - Metallic powder containing lubricating or binding agentsMetallic powder containing organic material containing organic material comprising solvents, e.g. for slip casting
• B22F 1/12 - Metallic powder containing non-metallic particles
• C22C 14/00 - Alloys based on titanium

Abstract

A method for repairing a damaged area of a stealth composite structure having a stealth function using a scarf patch includes the steps of diagnosing the damaged area; deriving a repair area including the diagnosed damaged area; processing the scarf patch according to the derived repair area; machining a patch hole according to the derived repair area to remove the damaged area; and coupling the scarf patch to the patch hole so that an inner wall of the patch hole and a side surface of the scarf patch face.

IPC Classes  ?

• B29C 73/10 - Repairing of articles made from plastics or substances in a plastic state, e.g. of articles shaped or produced by using techniques covered by this subclass or subclass using preformed elements using patches sealing on the surface of the article
• B64F 5/40 - Maintaining or repairing aircraft
• B64D 7/00 - Arrangement of military equipment, e.g. armaments, armament accessories or military shielding, in aircraftAdaptations of armament mountings for aircraft
• F41H 3/00 - Camouflage, i.e. means or methods for concealment or disguise
• H01Q 17/00 - Devices for absorbing waves radiated from an antenna Combinations of such devices with active antenna elements or systems

Abstract

The present invention relates to an influenza virus surface protein-derived recombinant hemagglutinin (HA) protein forming a trimer and use thereof, and more specifically to a recombinant vector for producing an influenza virus surface protein-derived HA protein forming a trimer, a transformant transformed by the recombinant vector, a method for producing an influenza virus surface protein-derived HA protein forming a trimer using the recombinant vector, an influenza virus surface protein-derived HA protein produced by the method, and the use thereof in preventing, ameliorating or treating influenza virus-infected disease.

IPC Classes  ?

• A61K 39/145 - Orthomyxoviridae, e.g. influenza virus
• C07K 14/005 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from viruses
• C12N 15/82 - Vectors or expression systems specially adapted for eukaryotic hosts for plant cells
• A61P 31/16 - Antivirals for RNA viruses for influenza or rhinoviruses

Abstract

The present invention relates to an electromagnetic wave-absorbing foam-based sandwich composite material for an aircraft, having a lightning protection metallic layer inserted therein, and a manufacturing method thereof. Particularly, the present invention relates to a composite material having electromagnetic-absorbing performance and protecting a structure below the metallic layer even after a lightning strike. The present invention provides an electromagnetic wave-absorbing foam-based sandwich composite material for an aircraft, having a lightning protection metallic layer inserted therein, the sandwich composite material comprising: dielectric fibers comprising at least one from among glass fibers, aramid fibers, and Kevlar fibers; plated dielectric fibers formed by electrolessly metal-plating the surface of the dielectric fibers to realize electromagnetic loss or electromagnetic wave absorption; a foam core stacked below the dielectric fibers and the plated dielectric fibers; and a metallic layer stacked below the foam core and having periodic circular patterns in order to achieve radar cross section (RCS) reduction and lightning protection.

IPC Classes  ?

• B32B 7/025 - Electric or magnetic properties
• B32B 5/18 - Layered products characterised by the non-homogeneity or physical structure of a layer characterised by features of a layer containing foamed or specifically porous material
• B32B 5/24 - Layered products characterised by the non-homogeneity or physical structure of a layer characterised by the presence of two or more layers which comprise fibres, filaments, granules, or powder, or are foamed or specifically porous one layer being a fibrous or filamentary layer
• B32B 5/26 - Layered products characterised by the non-homogeneity or physical structure of a layer characterised by the presence of two or more layers which comprise fibres, filaments, granules, or powder, or are foamed or specifically porous one layer being a fibrous or filamentary layer another layer also being fibrous or filamentary
• B32B 15/04 - Layered products essentially comprising metal comprising metal as the main or only constituent of a layer, next to another layer of a specific substance
• H01Q 17/00 - Devices for absorbing waves radiated from an antenna Combinations of such devices with active antenna elements or systems
• H05K 9/00 - Screening of apparatus or components against electric or magnetic fields

Abstract

A fertilizer composition according to an embodiment may reduce methane gas emission. The fertilizer composition includes ethephon as an effective component, and has an excellent effect of reducing the emission amount of methane gas from soils in which crops are cultivated. As the fertilizer application can be reduced to one application, labor can be saved and also environmental contamination can be prevented.

IPC Classes  ?

• A01G 22/22 - Rice
• C05G 3/00 - Mixtures of one or more fertilisers with additives not having a specifically fertilising activity
• C05G 5/40 - Fertilisers incorporated into a matrix
• C05D 9/00 - Other inorganic fertilisers
• C09K 17/32 - PrepolymersMacromolecular compounds of natural origin, e.g. cellulosic materials
• C09K 17/22 - PolyacrylatesPolymethacrylates
• A01N 57/20 - Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals
• A01P 21/00 - Plant growth regulators

Abstract

The present invention relates to a method for predicting the severity of radiation pneumonitis in non-small cell lung cancer patients who have undergone concurrent chemoradiotherapy. The present inventors have identified the specific up- or down-regulated index cytokines and the specific time points at which the levels change according to the severity of radiation pneumonitis developed in non-small cell lung cancer patients who have undergone concurrent chemoradiotherapy. The cytokines of the present invention are measured three weeks after radiation treatment, such that the severity of radiation pneumonitis can be effectively predicted or diagnosed, and it is expected that the present invention can aid in reducing the risk of misdiagnosis and establishing an accurate treatment method for radiation pneumonitis and non-small cell lung cancer.

IPC Classes  ?

• G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
• C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material

Abstract

The present invention relates to a composition for prevention, mitigation or treatment of degenerative brain disease, containing cycloastragenol as an active ingredient, whereby, by administering cycloastragenol, which is an active ingredient of the present invention, to an amyloid-β-induced Alzheimer's disease animal, variations in the expression level of a protein associated with degenerative brain disease may be adjusted, and cognitive function may be enhanced.

IPC Classes  ?

• A61K 31/58 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
• A61K 36/481 - Astragalus (milkvetch)
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
• A23L 33/10 - Modifying nutritive qualities of foodsDietetic productsPreparation or treatment thereof using additives

Abstract

The present invention relates to a composition for preparing retinoid, and more specifically, the composition comprises: NADH or NADPH; a beta-carotene oxygenase; and a flavodoxin or ferredoxin, a reductase of a flavodoxin or ferredoxin, a microorganism expressing the same, or a cultured product or a ground product of the microorganism, and thus can expand the supply metabolism of reducing electrons to enhance retinoid productivity through an increase in the activity of the cytochrome P450 system and provide a foundation for the low-cost production of raw materials, and thereby enhance the economic feasibility and efficiency of retinoid production.

IPC Classes  ?

• C12P 23/00 - Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
• C12N 9/02 - Oxidoreductases (1.), e.g. luciferase
• C07K 14/245 - Escherichia (G)
• C12N 15/70 - Vectors or expression systems specially adapted for E. coli
• C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
• C12N 9/10 - Transferases (2.)

Abstract

The present invention relates to a fluorine- and biphenyl-based branched copolymer polymer electrolyte membrane that is chemically stable because a polymer main chain thereof is composed of carbon single bonds, and has high hydrogen ion conductivity due to a cation exchange functional group introduced at the end of a carbon branch, and to a water electrolysis device and a fuel cell using same.

IPC Classes  ?

• C25B 13/08 - DiaphragmsSpacing elements characterised by the material based on organic materials
• C25B 1/04 - Hydrogen or oxygen by electrolysis of water
• C08J 5/22 - Films, membranes or diaphragms
• C08G 61/02 - Macromolecular compounds containing only carbon atoms in the main chain of the macromolecule, e.g. polyxylylenes