Institute of Pharmacology and Toxicology Medical Sciences P.L.A. China

China

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IPC Class
C07D 295/194 - Radicals derived from thio- or thiono carboxylic acids 1
C07D 295/215 - Radicals derived from nitrogen analogues of carbonic acid 1
Found results for  patents

1.

Hexenone compounds and medical use thereof

      
Application Number 13696697
Grant Number 08884007
Status In Force
Filing Date 2011-05-16
First Publication Date 2013-05-09
Grant Date 2014-11-11
Owner Institute of Pharmacology and Toxicology Medical Sciences P.L.A. China (China)
Inventor
  • Li, Song
  • Zhong, Wu
  • Liu, Juan
  • Wang, Lili
  • He, Kunlun
  • Long, Long
  • Xiao, Junhai
  • Zheng, Zhibing
  • Li, Wei
  • Li, Xin
  • Hu, Guoliang

Abstract

The present invention relates to a compound of Formula I, or an isomer, pharmaceutically acceptable salt and solvate thereof; to a composition comprising a compound of Formula I, or an isomer, pharmaceutically acceptable salt and solvate thereof, and a pharmaceutically acceptable carrier, excipient or diluent; and also to use of a compound of Formula I, or an isomer, pharmaceutically acceptable salt and solvate thereof for combating apoptosis, or preventing or treating a disease or disorder associated with apoptosis; and especially use for protecting cardiomyocyte, or preventing or treating a disease or disorder associated with cardiomyocyte apoptosis.

IPC Classes  ?

  • C07D 295/215 - Radicals derived from nitrogen analogues of carbonic acid
  • C07D 295/194 - Radicals derived from thio- or thiono carboxylic acids