Goods & Services

Chemical preparations for scientific purposes, other than for medical or veterinary use; Fine Chemicals, Speciality Chemicals and Intermediates; Peptides; Synthesis intermediates and chemicals for use in the pharmaceutical; Cosmetology and Biotech Products for use in manufacturing Pharmaceuticals; Chemicals for cosmetic and veterinary industry and for use in agriculture; Chemical reagents, other than for medical or veterinary purposes. Medicinal and Pharmaceutical Preparations (Active pharmaceutical ingredients used in the preparation of medicinal and pharmaceutical products); Manufacturing of Medicinal formulation; Drug Substances; Pharmaceutical Ingredients and Intermediates; Antibody Drug Conjugate (ADC); Supplements & Nutritional/Nutraceuticals Additives; Nutraceuticals; Vaccines. Advertising, marketing, distribution, import and export of Active pharmaceutical ingredients used in the preparation of medicinal and pharmaceutical products; Advertising services for third parties; Advertising via the Internet for others; Demonstration and sales promotion for others. Research and Development Services and Contract Development for Biochemical; Research and Development for Biotech and Biochemistry products; Research and Development for Electrolytes, Semiconductors, and Battery Chemicals; Research and Development for Cosmetics, Nutraceuticals, Vaccines and Agrochemicals; Chemical research; quality control testing of Chemicals.

Goods & Services

Chemical preparations for scientific purposes, other than for medical or veterinary use; Fine Chemicals, Speciality Chemicals and Intermediates; Peptides; Synthesis intermediates and chemicals for use in the pharmaceutical; Cosmetology and Biotech Products for use in manufacturing Pharmaceuticals; Chemicals for cosmetic and veterinary industry and for use in agriculture; Chemical reagents, other than for medical or veterinary purposes. Medicinal and Pharmaceutical Preparations (Active pharmaceutical ingredients used in the preparation of medicinal and pharmaceutical products); Manufacturing of Medicinal formulation; Drug Substances; Pharmaceutical Ingredients and Intermediates; Antibody Drug Conjugate (ADC); Supplements & Nutritional/Nutraceuticals Additives; Nutraceuticals; Vaccines. Advertising, marketing, distribution, import and export of Active pharmaceutical ingredients used in the preparation of medicinal and pharmaceutical products; Advertising services for third parties; Advertising via the Internet for others; Demonstration and sales promotion for others. Research and Development Services and Contract Development for Biochemical; Research and Development for Biotech and Biochemistry products; Research and Development for Electrolytes, Semiconductors, and Battery Chemicals; Research and Development for Cosmetics, Nutraceuticals, Vaccines and Agrochemicals; Chemical research; quality control testing of Chemicals.

Abstract

The present invention relates to Tegoprazan Fendizoate of Formula-II and Tegoprazan Salicylate of Formula-IV. The present invention also relates to an efficient and industrially advantageous process for the preparation of Tegoprazan Fendizoate of Formula-II and Tegoprazan Salicylate of Formula- IV.

IPC Classes  ?

• A61K 31/4184 - 1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
• C07D 405/12 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
• A61P 1/04 - Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Abstract

The present invention relates to an efficient and industrially scalable continuous recyclable enzymatic process for preparation of Sitagliptin or salts thereof. The present invention also relates to a process for the preparation of Sitagliptin hydrochloride or hydrate thereof. The present invention also relates to a process for the preparation of Sitagliptin phosphate or hydrate thereof.

IPC Classes  ?

• C12P 17/18 - Preparation of heterocyclic carbon compounds with only O, N, S, Se, or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
• C12N 9/10 - Transferases (2.)

Abstract

The present invention relates to an efficient and industrially advantageous process for the preparation of Pemafibrate intermediates namely 3-[[2-benzoxazolyl[3-(4- methoxyphenoxy)propyl]amino]methyl]phenol of Formula IV, Pemafibrate ethyl ester of Formula VI and their use for the preparation of Pemafibrate of Formula-I or salt thereof.

IPC Classes  ?

• C07D 263/58 - BenzoxazolesHydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
• A61K 31/423 - Oxazoles condensed with carbocyclic rings

Abstract

The present invention relates to solid forms comprising Roxadustat of Formula I and co-former camphorsulfonic acid of Formula II. The present invention also relates to a process for the preparation of solid forms comprising Roxadustat of Formula I and co-former camphorsulfonic acid of Formula II.

IPC Classes  ?

• C07D 217/26 - Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
• C07D 487/04 - Ortho-condensed systems

Abstract

The present invention provides improved process for preparation of Molnupiravir compound of formula (I) The present invention provides improved process for preparation of Molnupiravir compound of formula (I) The present invention provides improved process for preparation of Molnupiravir compound of formula (I) having high purity and yield by avoiding excess use of organic solvent and tedious column chromatography purification. further present invention provides improved process for preparation of compound of formula (V) The present invention provides improved process for preparation of Molnupiravir compound of formula (I) having high purity and yield by avoiding excess use of organic solvent and tedious column chromatography purification. further present invention provides improved process for preparation of compound of formula (V) The present invention provides improved process for preparation of Molnupiravir compound of formula (I) having high purity and yield by avoiding excess use of organic solvent and tedious column chromatography purification. further present invention provides improved process for preparation of compound of formula (V) in single step reaction having high yield and high purity.

IPC Classes  ?

• C07H 19/067 - Pyrimidine radicals with ribosyl as the saccharide radical
• C07H 1/00 - Processes for the preparation of sugar derivatives

Abstract

The present invention relates to an efficient and industrially advantageous process for the preparation of Vadadustat of Formula-(I) or salt thereof. The present invention also relates to a process for the preparation of Vadadustat intermediates namely {[3-chloro-5-(3-chlorophenyl)pyridine-2-carbonyl]amino}acetic acid of Formula-(IV), {[5-(3- chlorophenyl)-3-methoxypyridine-2-carbonyl]amino}acetic acid of Formula-(V) and their use for the preparation of Vadadustat or salt thereof. The present invention also relates to Vadadustat salt of Formula-(VI), and process thereof.

IPC Classes  ?

• C07D 213/81 - AmidesImides

Abstract

The present invention relates to an efficient and industrially advantageous process for the preparation of Edoxaban of Formula-I or salt thereof. The present invention also relates to a process for preparation of Edoxaban intermediates namely methyl 2-[(5-chloropyridin-2-yl)amino]-2-oxoacetate hydrochloride of Formula-II, tert-Butyl [(1R,2S,5S)-2-[[2-[(5-5 chloropyridin-2-yl)amino]-2-oxoacetyl]amino]-5-(dimethylaminocarbonyl)cyclohexyl] carbamate of Formula-IV, and their use for the preparation of Edoxaban or salt thereof.

IPC Classes  ?

• A61K 31/444 - Non-condensed pyridinesHydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. amrinone
• A61P 7/02 - Antithrombotic agentsAnticoagulantsPlatelet aggregation inhibitors
• C07D 513/04 - Ortho-condensed systems
• C07D 213/75 - Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates

Abstract

The present invention provides improved process for preparation of Molnupiravir compound of formula (I) having high purity and yield by avoiding excess use of organic solvent & tedious column chromatography purification. further present invention provides improved process for preparation of compound of formula (V) in single step reaction having high yield and high purity.

IPC Classes  ?

• A61K 31/706 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
• C07C 67/32 - Decarboxylation

Abstract

The present invention relates to an improved process for preparing Acebrophylline comprising preparing a reaction mixture of theophylline-7-acetate and ambroxol base in a non-polar solvent; heating said reaction mixture at a suitable temperature; and isolating Acebrophylline by filtration. The yield of Acebrophylline is between 95-98 % with a purity of 99%.

IPC Classes  ?

• A61K 31/522 - Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir