05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations for prevention of heart and prostate diseases; Pharmaceutical preparations in the form of tablets, pharmaceutical tablets, and tablets for medicines for prevention of heart and prostate diseases; Nutraceuticals for use as a dietary supplement for health benefits; Food and Dietary supplements for health benefits; dietetic foods and beverages for human consumption adapted for medical purposes as an antioxidant; all of the foregoing include lycopene phytonutrient extracted from tomatoes as an ingredient
Syzygium cumini. Also provided is the use of herbal composition for the treatment of disorders related to metabolic syndrome. Also provided is a method of treating disorders related to metabolic syndrome comprising administering to a subject in need thereof a therapeutically effective amount of the herbal composition of the present invention.
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
A61K 36/9066 - Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
A61K 9/00 - Medicinal preparations characterised by special physical form
The present invention generally relates to an herbal composition effective in management of disorders related to metabolic syndrome. More particularly, the invention relates to an herbal composition effective in the management of disorders related to metabolic syndrome such as Type 2 diabetes mellitus, obesity and lipid profile management and a process for the preparation of such an herbal composition. The invention further relates to the use of the herbal composition in preparation of food supplements, pharmaceuticals and nutraceuticals for the management of disorders related to metabolic syndrome. The herbal composition effective in management of metabolic syndrome related disorders comprises of herbs selected from Curcuma longa, Emblica officinalis, Vernonia anthelmintica, Tinospora cordifolia, Trigonella foenum-graecum, Ixora coccinea and Syzygium cumini. Also provided is the use of herbal composition for the treatment of disorders related to metabolic syndrome. Also provided is a method of treating disorders related to metabolic syndrome comprising administering to a subject in need thereof a therapeutically effective amount of the herbal composition of the present invention.
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
A61K 36/59 - Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
A61K 36/9066 - Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
A61P 3/10 - Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
4.
Process for isolation of lutein and zeaxanthin crystals from plant sources
The present invention provides for a process for isolation of carotenoids crystals comprising drying a plant part to obtain a meal and extracting the meal with alcohol at a temperature in the range of about 50° C. to 75° C. to obtain oleoresin. The oleoresin is enriched with alcohol at a temperature in the range of about 25° C. ° C. to 50° C. and hydrolyzed with alcoholic alkali at a temperature in the range of about 70° C. to 80° C. to obtain reaction mixture. The carotenoids crystals are precipitated from the reaction mixture by adding hot water followed by filtering, washing and drying the carotenoids crystals. The present invention also relates to carotenoids crystals comprising lutein and zeaxanthin in the ratios of about 10:1 or 5:1 or 1:1 obtained by a process which comprises mixing an oleoresin rich in lutein and an oleoresin rich in zeaxanthin separately in a ratios ranging from about 80:20 (w/w) to 90:10 (w/w) or about 70:30 (w/w) to 30:70 (w/w) or about 10:90 (w/w) to 20:80 (w/w) and homogenized to obtain a mixed oleoresin. The mixed oleoresin is then hydrolyzed with an alcoholic alkali at a temperature of about 70° C. to 80° C. to obtain a reaction mixture. The carotenoids crystals are precipitated by adding hot water to the reaction mixture to form a precipitate. Carotenoids crystals having lutein and zeaxanthin in a weight ratio of about 10:1 or 5:1 or 1:1 respectively are obtained by filtering, washing and drying the precipitate.
A01N 65/00 - Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
5.
A PROCESS FOR ISOLATION OF LUTEIN AND ZEAXANTHIN CRYSTALS FROM PLANT SOURCES
The present invention provides for a process for isolation of carotenoids crystals comprising drying a plant part to obtain a meal and extracting the meal with alcohol at a temperature in the range of about 50°C to 75°C to obtain oleoresin. The oleoresin is enriched with alcohol at a temperature in the range of about 25°C °C to 50°C and hydrolyzed with alcoholic alkali at a temperature in the range of about 70°C to 80°C to obtain reaction mixture. The carotenoids crystals are precipitated from the reaction mixture by adding hot water followed by filtering, washing and drying the carotenoids crystals. The present invention also relates to carotenoids crystals comprising lutein and zeaxanthin in the ratios of about 10:1 or 5:1 or 1:1 obtained by a process which comprises mixing an oleoresin rich in lutein and an oleoresin rich in zeaxanthin separately in a ratios ranging from about 80:20 (w/w) to 90:10 (w/w) or about 70:30 (w/w) to 30:70 (w/w) or about 10:90 (w/w) to 20:80 (w/w) and homogenized to obtain a mixed oleoresin. The mixed oleoresin is then hydrolyzed with an alcoholic alkali at a temperature of about 70°C to 80°C to obtain a reaction mixture. The carotenoids crystals are precipitated by adding hot water to the reaction mixture to form a precipitate. Carotenoids crystals having lutein and zeaxanthin in a weight ratio of about 10:1 or 5:1 or 1:1 respectively are obtained by filtering, washing and drying the precipitate.
C07C 403/24 - Derivatives of cyclohexane or of a cyclohexene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by six-membered non-aromatic rings, e.g. beta-carotene
A process for isolation of carotenoids crystals having lutein and zeaxanthin in a weight ratio of about 10:1, 5:1 or 1:1. The process comprises contacting a plant source rich in lutein with hexane and extracting at a temperature of about 40° C. to 60° C. to obtain an oleoresin rich in lutein; contacting a plant source rich in zeaxanthin with hexane and extracting at a temperature of about 40° C. to 60° C. to obtain an oleoresin rich in zeaxanthin. The oleoresin rich in lutein and the oleoresin rich in zeaxanthin are mixed separately in a ratios ranging from about 80:20 (w/w) to 90:10 (w/w) or about 70:30 (w/w) to 30:70 (w/w) or about 10:90 (w/w) to 20:80 (w/w) and homogenized to obtain a mixed oleoresin. The mixed oleoresin is hydrolyzed with an alcoholic alkali at a temperature of about 70° C. to 80° C. to obtain a reaction mixture. The carotenoids crystals are precipitated by adding hot water to the reaction mixture to form a precipitate. Carotenoids crystals having lutein and zeaxanthin in a ratio of about 10:1 or 5:1 or 1:1 respectively are obtained by filtering, washing and drying the precipitate.
C11B 1/10 - Production of fats or fatty oils from raw materials by extracting
C07C 35/21 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a non-condensed ring
