40 - Treatment of materials; recycling, air and water treatment,
Goods & Services
Custom manufacture of pharmaceuticals, medical and veterinary preparations, sanitary preparations for medical purposes, dietetic foodstuffs and products for medical or veterinary purposes, food supplements for humans and animals, disinfectants, medicines and natural remedies, dietetic preparations and food supplements and pharmaceutical preparations and substances, dietary supplements and dietetic preparations, food for babies and infants, beverages for infants and infant formula; Custom manufacture of oils and fats, dietary oils and fats, edible oils and fats, oils and fats for the production of edible oils and fats; Custom manufacture of pharmaceutical, food and dietary supplements and pharmaceutical preparations and substances for medical purposes with omega-3 extracts contained therein in the form of oils, fats, powders or capsules for third parties; none of the foregoing featuring or providing cannabis or cannabis derived ingredients with a delta-9 tetrahydrocannabinol (THC) concentration of not more than 0.3 percent on a dry weight basis; none of the foregoing services featuring or providing cannabidiol (CBD)
2.
CHROMATOGRAPHY METHOD AND DEVICE, IN PARTICULAR METHOD AND DEVICE FOR SUPERCRITICAL LIQUID CHROMATOGRAPHY
This version will replace all prior versions in the application: A chromatography method in which a starting material is separated into fractions and at least one of the fractions which have at least a predetermined target content of at least one target component of the starting material is derived as a target product fraction. The fractions which do not have the predetermined target content form residual fractions and at least part of at least one of the residual fractions is added to the starting material still to be separated. At least part of at least one of the residual fractions of which the content of the target component differs less from the predetermined target content than the target component content of the starting material is added to the starting material still to be separated. The residual fractions of which the target component content differs more from the predetermined target content than that of the starting material are diverted for further handling.
05 - Pharmaceutical, veterinary and sanitary products
29 - Meat, dairy products, prepared or preserved foods
Goods & Services
Dietary supplements and food supplements; dietetic
substances and foods adapted for medical and veterinary use. Dietetic oils and dietetic fats, including being primary
products used in industry; edible oils and fats, and oils
and greases for manufacturing edible oils and fats;
margarine and other fat-containing mixtures for bread
slices; sauces consisting predominantly of edible oils and
fats; meat, fish, poultry and game products; meat extracts;
meat; preserved and cooked fruits and vegetables; canned
mushrooms; jellies; marmalade; egg products; milk products;
potato chips.
A method and apparatus for isolating a first substance from a mixture by chromatography, the mixture including at least a second substance which in the chromatography is subject to a greater retention than the first substance, and having a third substance which in the chromatography is subject to a lower retention than the first substance. The mixture is supplied to a chromatography apparatus having multiple interconnected chromatography columns. The apparatus is supplied with the mixture and an eluent, and the second substance is withdrawn as an extract and the first substance as a raffinate. The third substance is withdrawn as an extract. Usefully the third substance and the second substance are withdrawn jointly as an extract.
B01D 15/18 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
C07C 37/82 - SeparationPurificationStabilisationUse of additives by physical treatment by solid-liquid treatmentSeparationPurificationStabilisationUse of additives by physical treatment by chemisorption
C07C 51/47 - SeparationPurificationStabilisationUse of additives by solid-liquid treatmentSeparationPurificationStabilisationUse of additives by chemisorption
C07D 311/78 - Ring systems having three or more relevant rings
29 - Meat, dairy products, prepared or preserved foods
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Dietetic oils and dietetic fats, including being primary products used in industry; edible oils and fats, and oils and greases for manufacturing edible oils and fats; margarine and other fat-containing mixtures for bread slices; sauces consisting predominantly of edible oils and fats; meat, fish, poultry and game products; meat extracts; meat; preserved and cooked fruits and vegetables; canned mushrooms; jellies; marmalade; egg products; milk products; potato chips. Dietary supplements and food supplements; dietetic substances and foods adapted for medical and veterinary use.
05 - Pharmaceutical, veterinary and sanitary products
29 - Meat, dairy products, prepared or preserved foods
Goods & Services
Pharmaceutical, medical and veterinary preparations;
sanitary preparations for medical purposes; dietetic foods
and products for medical or veterinary use; food supplements
for humans and animals; medicines and natural remedies;
dietetic preparations and food supplements; pharmaceutical
preparations and substances; dietary supplements and
dietetic preparations; extracts from medicinal plants; plant
extracts for pharmaceutical purposes; plant and herbal
extracts for medicinal purposes. Oils and fats; dietetic oils and fats, whether or not as
intermediate products for industrial use; edible oils and
fats; oils and fats for the manufacture of edible oils and
fats.
7.
METHOD FOR PROCESSING A SEPARATION PRODUCT, CONTAINING CARBOXYLIC ACIDS, OF A SEPARATION PROCESS
The invention relates to a method for processing a separation product, containing carboxylic acids, of a separation process, in particular a process for separating fish oil and/or algae oil, in which method polyunsaturated hydrocarbons are produced at least from some of the carboxylic acids by means of microbes. Advantageously, the polyunsaturated hydrocarbons are or comprise omega-3 fatty acids and/or omega-6 fatty acids, preferably EPA, DHA and/or DPA. In an embodiment of the invention, the microbes are or comprise yeast, fungus, bacteria and/or in particular marine protists, preferably microalgae. The yeast is preferably a yeast of the Yarrowia lipolytica species and the marine protist is preferably a microalga of the Schizochytrium genus, preferably Schizochytrium limacinum SR21. The invention further relates to biomass which is produced from microbes and comprises polyunsaturated hydrocarbons.
A method for producing edible oil, having a high content of unsaturated fatty acids, from a product of microalgae. The microalgae product is treated to form an intermediate product that is subjected to a material separation process for removing impurities, in which material separation process the triglyceride is used as a carrier for the impurities. A microalgae oil and/or a lipid extract is advantageously used as the microalgae product. The microalgae product is preferably obtained from microalgae, more particularly photoautotrophic and/or mixotrophic microalgae. The microalgae product is treated by transesterification in order to form the intermediate product, wherein the microalgae product is preferably transformed into an ethyl ester. An organic phase is separated from an inorganic phase of the intermediate product and the organic phase of the intermediate product is subjected to a material separation process for removing impurities, in which material separation process the triglyceride is used.
C11C 3/04 - Fats, oils or fatty acids obtained by chemical modification of fats, oils or fatty acids, e.g. by ozonolysis by esterification of fats or fatty oils
A method for extraction, in which an extraction agent is used for dissolving at least one extraction material out of a substance. The extraction agent includes fatty acid ethyl ester and/or fatty acid methyl ester. In one embodiment the extraction agent is an omega-3 and/or omega-6 fatty acid, preferably EPA, DHA, DPA, ETA, 21:5n3 and/or SDA. In one embodiment the extraction agent includes at least 500 mg/g, preferably at least 700 mg/g of the fatty acid ethyl ester and/or of the fatty acid methyl ester. Expediently, the mixture of substances is a plant material, preferably hemp, and the extraction material is a cannabinoid, preferably CBD and/or THC.
The invention relates to a chromatography method, in particular a method for supercritical liquid chromatography, in which a starting material to be separated is separated into fractions by means of chromatography and at least one of the fractions which have at least a predetermined target content of at least one target component of the starting material is derived as a target product fraction. According to the invention, the fractions which do not have the predetermined target content form residual fractions and at least part of at least one of the residual fractions is added to the starting material still to be separated. Expediently, at least part of at least one of the residual fractions of which the content of the target component differs less from the predetermined target content than the target component content of the starting material is added to the starting material still to be separated. In an embodiment of the invention, the residual fractions of which the target component content differs more from the predetermined target content than that of the starting material are diverted for further handling, in particular further processing and/or disposal.
The invention relates to a method for isolating a first substance from a mixture by chromatography, the mixture comprising at least a second substance which in the chromatography is subject to a greater retention than the first substance, and comprising a third substance which in the chromatography is subject to a lower retention than the first substance, where the mixture is supplied to a chromatography apparatus (1) comprising multiple interconnected chromatography columns (2, 3, 4, 5), the apparatus (1) being supplied with the mixture and an eluent, and the second substance is withdrawn as an extract and the first substance as a raffinate. The object of the invention is achieved by the withdrawal of the third substance as an extract. Usefully the third substance and the second substance are withdrawn jointly as an extract. The invention further relates to an apparatus (1) for carrying out the method.
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
29 - Meat, dairy products, prepared or preserved foods
Goods & Services
Oils and fats, namely, lipids used in the manufacture of cosmetics, beverages, food products, pharmaceuticals and dietary supplements for the manufacture of pharmaceuticals, medical and veterinary preparations, sanitary preparations for medical purposes, dietetic foodstuffs and products for medical or veterinary purposes, food supplements for humans and animals, medicines and natural remedies, dietetic preparations and food supplements and pharmaceutical preparations and substances, dietary supplements and dietetic preparations, food for babies and infants, and for manufacturing beverages for infants and infant formula; any cannabis or cannabis derived ingredients in the goods being solely derived from hemp with a delta-9 tetrahydrocannabinol (THC) concentration of not more than 0.3 percent on a dry weight basis; none of the foregoing containing cannabidiol (CBD) Pharmaceutical, medical and veterinary preparations, namely, pharmaceutical preparations and substances for the treatment of infectious diseases, blood disorders, pain, inflammation, sepsis, alopecia, obesity and cognitive disorders, pharmaceutical products for the prevention and treatment of cancer, pharmaceutical preparations and substances for the treatment of viral, metabolic, endocrine, musculoskeletal, cardiovascular, cardiopulmonary, genitourinary, sexual dysfunction, oncological, hepatological, ophthalmic, respiratory, neurological, gastrointestinal, hormonal, dermatological, psychiatric and immune system related diseases and disorders, pharmaceutical preparations for the prevention and treatment of ocular disorders or diseases, for the treatment of bacteria-based diseases, and for the treatment of diabetes, and anti-infective preparations, antiviral preparations, antibiotics, antifungal preparations and vaccines, and chemical reagents for medical or veterinary purposes, chemical reagents for medical or veterinary purposes; sanitary preparations for medical purposes; dietetic foodstuffs and goods for medical or veterinary purposes, namely, dietetic foods and beverages adapted for medical use, dietetic foods adapted for veterinary use, dietetic beverages adapted for veterinary use, and dietetic preparations adapted for medical purposes; food supplements for humans and animals; disinfectants; medicines and natural remedies, namely medicinal oils and antiallergic medicines, medicinal preparations for the treatment of infectious diseases and for use in oncology, medicinal drinks, medicinal preparations for infectious diseases, blood disorders, pain, inflammation, sepsis, alopecia, obesity and cognitive disorders, for the prevention and treatment of cancer, for the treatment of viral, metabolic, endocrine, musculoskeletal, cardiovascular, cardiopulmonary, genitourinary, sexual dysfunction, oncological, hepatological, ophthalmic, respiratory, neurological, gastrointestinal, hormonal, dermatological, psychiatric and immune system related diseases and disorders, for the prevention and treatment of ocular disorders or diseases, for the treatment of bacteria- based diseases, for the treatment of epilepsy, pain, anxiety, depression, sleep disorders, Parkinson's disease, nausea and vomiting, food disorders, arthritis, PTSD, schizophrenia, opioid addiction, alleviate ALS symptoms, multiple sclerosis, and for the treatment of diabetes, natural remedy preparations for the treatment of gastro-intestinal conditions, hormonal and chemical imbalances, and sleep disorders; dietetic preparations, namely Dietetic preparations adapted for medical purposes; food supplements; food for babies; food for infants; infant formula; any cannabis or cannabis derived ingredients in the goods being solely derived from hemp with a delta-9 tetrahydrocannabinol (THC) concentration of not more than 0.3 percent on a dry weight basis; none of the foregoing containing cannabidiol (CBD) Oils and fats, namely edible oils and edible fats and oils and fats for food; dietetic oils and fats in the nature of edible oils and fats, not for medical purposes; any cannabis or cannabis derived ingredients in the goods being solely derived from hemp with a delta-9 tetrahydrocannabinol (THC) concentration of not more than 0.3 percent on a dry weight basis; none of the foregoing containing cannabidiol (CBD)
The invention relates to a method for extraction, in which an extraction agent is used for dissolving at least one extraction material out of a substance. According to the invention the extraction agent comprises fatty acid ethyl ester and/or fatty acid methyl ester. In one embodiment of the invention the extraction agent is an omega-3 and/or omega-6 fatty acid, preferably EPA, DHA, DPA, ETA, 21:5n3 and/or SDA. In one embodiment of the invention the extraction agent comprises at least 500 mg/g, preferably at least 700 mg/g of the fatty acid ethyl ester and/or of the fatty acid methyl ester. Expediently, the mixture of substances is a plant material, preferably hemp, and the extraction material is a cannabinoid, preferably CBD and/or THC.
The invention relates to a method for producing oil, more particularly edible oil, having a high content of unsaturated fatty acids, from a product of microalgae. According to the invention, the microalgae product is treated, an intermediate product thus being formed, and the intermediate product is subjected to a material separation process for removing impurities, in which material separation process the triglyceride is used as a carrier for the impurities. A microalgae oil and/or a lipid extract is advantageously used as the microalgae product. The microalgae product is preferably obtained from microalgae, more particularly photoautotrophic and/or mixotrophic microalgae. In one embodiment of the invention, the microalgae product is treated by means of transesterification in order to form the intermediate product, wherein the microalgae product is preferably transformed into an ethyl ester. In one embodiment of the invention, an organic phase is separated from an inorganic phase of the intermediate product and the organic phase of the intermediate product is subjected to a material separation process for removing impurities, in which material separation process the triglyceride is used.
C11C 3/08 - Fats, oils or fatty acids obtained by chemical modification of fats, oils or fatty acids, e.g. by ozonolysis by esterification of fats or fatty oils with fatty acids
05 - Pharmaceutical, veterinary and sanitary products
40 - Treatment of materials; recycling, air and water treatment,
42 - Scientific, technological and industrial services, research and design
Goods & Services
Pharmaceutical and veterinary products; sanitary
preparations for medical purposes; dietetic foodstuffs and
preparations for medical or veterinary purposes; dietary
supplements for humans and animals; pharmaceutical products,
nutritional supplements and dietetic preparations for
medical purposes containing omega-3-extracts in the form of
oils, powders and capsules. Contract manufacturing of pharmaceutical products, dietary
supplements and dietetic products for medical purposes
containing omega-3-extracts in the form of oils, powders and
capsules for others. Scientific and technological services and research studies;
research and development in the field of lipid extraction
from natural resources; scientific, pharmaceutical and
chemical laboratory services, in particular the extraction
of lipids and other by-prodcuts from fish oil and plants for
others; scientific and industrial research relating to the
manufacture of pharmaceutical products, dietary supplements
and dietetic products or medical purposes containing
omega-3-extracts in the form of oils, powders and capsules
for others.
05 - Pharmaceutical, veterinary and sanitary products
40 - Treatment of materials; recycling, air and water treatment,
42 - Scientific, technological and industrial services, research and design
Goods & Services
Pharmaceutical and veterinary products, namely, pharmaceutical preparations and substances for the treatment of infectious diseases, blood disorders, pain, inflammation, sepsis, alopecia, obesity and cognitive disorders, pharmaceutical products for the prevention and treatment of cancer, pharmaceutical preparations and substances for the treatment of viral, metabolic, endocrine, musculoskeletal, cardiovascular, cardiopulmonary, genitourinary, sexual dysfunction, oncological, hepatological, ophthalmic, respiratory, neurological, gastrointestinal, hormonal, dermatological, psychiatric and immune system related diseases and disorders, pharmaceutical preparations for the prevention and treatment of ocular disorders or diseases, for the treatment of bacteria-based diseases, and for the treatment of diabetes, and anti - infective preparations, antiviral preparations, antibiotics, antifungal preparations and vaccines, and chemical reagents for medical or veterinary purposes; sanitary preparations for medical use; dietetic foodstuffs and preparations for medical or veterinary purposes, namely, dietetic foods and beverages adapted for medical use, dietetic foods adapted for veterinary use, dietetic beverages adapted for veterinary use, and dietetic preparations adapted for medical purposes; dietary supplements for humans and animals; pharmaceutical products in the nature of oils, powders and capsules containing omega-3-extracts for the treatment of viral, metabolic, endocrine, musculoskeletal, cardiovascular, cardiopulmonary, genitourinary, sexual dysfunction, oncological, hepatological, ophthalmic, respiratory, neurological, gastrointestinal, hormonal, dermatological, psychiatric and immune system related diseases and disorders; nutritional supplements; dietetic preparations adapted for medical purposes containing omega-3-extracts and in the form of oils, powders and capsules containing omega-3-extracts Contract manufacturing for others of pharmaceutical products, dietary supplements and dietetic products for medical purposes containing omega-3-extracts in the form of oils, powders and capsules Scientific and technological services, namely, pharmaceutical research and development, pharmaceutical products development, testing of pharmaceuticals, development of pharmaceutical preparations and medicines, scientific research in the field of pharmaceuticals, pharmaceutical research services, laboratory research services relating to pharmaceuticals, scientific analysis in the field of nutritional supplements; scientific research and development in the field of lipid extraction from natural resources; scientific laboratory services; chemical laboratories; scientific and industrial research for others relating to the manufacture of pharmaceutical products, dietary supplements and dietetic products for medical purposes containing omega-3-extracts in the form of oils, powders and capsules
40 - Treatment of materials; recycling, air and water treatment,
42 - Scientific, technological and industrial services, research and design
Goods & Services
Manufacturing services for others in the field of custom manufacturing of dietary supplements, nutritional supplements, food supplements, health foods, medical foods, over the counter (OTC) medicines and pharmaceutical drugs, for both human and animal consumption, including cosmetics; Contract manufacturing in the field of dietary supplements, nutritional supplements, food supplements, health foods, medical foods, over the counter (OTC) medicines and pharmaceutical drugs being encapsulation services to encapsulate, micro-encapsulate, and macroencapsulate ingredients for others Custom formulation development for dietary supplements, nutritional supplements, food supplements, health foods, medical foods, over the counter (OTC) medicines and pharmaceutical drugs, for both human and animal consumption; custom formulation development for cosmetics
An application of omega-3 and/or omega-6 fatty acid(s) for the therapeutic treatment of the human or animal body in the case of an impaired sphingolipid metabolism, in particular in the case of impaired sphingolipid synthesis and/or excessive sphingolipid degradation. The agent is applied in the case of missing, reduced and/or defective formation of a sphingomyelin synthase enzyme in the body, in particular the enzyme sphingomyelin synthase 1 or the enzyme sphingomyelin synthase 2. The application has proved to be useful in the case of a defect of the sphingomyelin synthase 1 gene or of the sphingomyelin synthase 2 gene. The omega-3 and/or omega-6 fatty acid(s) preferably comprise(s) polyunsaturated omega-3 and/or omega-6 fatty acid(s), preferably EPA, DHA, DPA, ETA, 21:5n3 and/or SDA. A method for determining a cause of a disease in an animal or a human being and a device for carrying out the method are also provided.
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
21.
Process for obtaining free fatty acid and/or fatty acid ester
A process for obtaining free fatty acid and/or free fatty acid ester, including separating a liquid mixture containing the free fatty acid and/or the fatty acid ester by contacting a vapor of the liquid mixture in a column of a distillation apparatus with condensate formed from the vapor running downward. Heat and mass transfer takes place between the vapor and the condensate on column internals. The column has at least 10 theoretical plates and the separation is conducted with a pressure drop between the top and bottom of the column of Δp of ≥3.3 mbars. Appropriately, the liquid mixture, contains polyunsaturated fatty acid, preferably omega-6 or omega-3 fatty acid and/or alkyl monoesters and/or glycerol monoesters. In one embodiment the column has at least 30 theoretical plates and the separation is conducted with a pressure drop Δp between 3.5 mbar and 6 mbar.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Dietary and nutritional supplements; Dietary food supplements; Dietary supplements and dietetic preparations; Dietary supplements for improving cognitive function; Dietary supplements for reducing inflammation; Dietary supplements for managing symptoms of PTSD; Dietary supplements for managing opioid withdrawal; Pharmaceutical preparations for the treatment of and for improving cognitive function; Pharmaceutical preparations for the treatment of and for reducing inflammation; Pharmaceutical preparations for the treatment of and for managing opioid withdrawal; Pharmaceutical preparations for the treatment of and for managing symptoms of PTSD.
24.
PROCESS FOR OBTAINING FREE FATTY ACID AND/OR FATTY ACID ESTER
The invention relates to a process for obtaining free fatty acid and/or free fatty acid ester, in which a liquid mixture containing the free fatty acid and/or the fatty acid ester is separated by contacting a vapour of the liquid mixture in a column of a distillation apparatus with condensate formed from the vapour running downward, wherein heat and mass transfer takes place between the vapour and the condensate on column internals. According to the invention, the column has at least 10 theoretical plates and the separation is conducted with a pressure drop between the top and bottom of the column ?p of = 3.3 mbar. Appropriately, the liquid mixture, preferably produced from vegetable oil or from fish oil, contains polyunsaturated fatty acid, preferably omega-6 or omega-3 fatty acid and/or alkyl monoesters and/or glycerol monoesters. In one configuration of the invention, the column has at least 30, preferably at least 40, theoretical plates and the separation is conducted with a pressure drop ?p between 3.5 mbar and 6 mbar.
The invention relates to a process for obtaining free fatty acid and/or free fatty acid ester, in which a liquid mixture containing the free fatty acid and/or the fatty acid ester is separated by contacting a vapour of the liquid mixture in a column of a distillation apparatus with condensate formed from the vapour running downward, wherein heat and mass transfer takes place between the vapour and the condensate on column internals. According to the invention, the column has at least 10 theoretical plates and the separation is conducted with a pressure drop between the top and bottom of the column Δp of ≥ 3.3 mbar. Appropriately, the liquid mixture, preferably produced from vegetable oil or from fish oil, contains polyunsaturated fatty acid, preferably omega-6 or omega-3 fatty acid and/or alkyl monoesters and/or glycerol monoesters. In one configuration of the invention, the column has at least 30, preferably at least 40, theoretical plates and the separation is conducted with a pressure drop Δp between 3.5 mbar and 6 mbar.
The invention relates to an application of omega-3 and/or omega-6 fatty acid(s) for the therapeutic treatment of the human or animal body in the case of an impaired sphingolipid metabolism, in particular in the case of impaired sphingolipid synthesis and/or excessive sphingolipid degradation. In an embodiment of the invention, the agent is applied in the case of missing, reduced and/or defective formation of a sphingomyelin synthase enzyme in the body, in particular the enzyme sphingomyelin synthase 1 or the enzyme sphingomyelin synthase 2. The application has proved to be useful in the case of a defect of the sphingomyelin synthase 1 gene or of the sphingomyelin synthase 2 gene. The omega-3 and/or omega-6 fatty acid(s) preferably comprise(s) polyunsaturated omega-3 and/or omega-6 fatty acid(s), preferably EPA, DHA, DPA, ETA, 21:5n3 and/or SDA. The invention further relates to a method for determining a cause of a disease in an animal or a human being and to a device for carrying out the method.
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A61P 15/08 - Drugs for genital or sexual disordersContraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
G01N 33/48 - Biological material, e.g. blood, urineHaemocytometers
27.
OMEGA-3 AND/OR OMEGA-6 FATTY ACID(S) IN IMPAIRED SPHINGOLIPID METABOLISM
The invention relates to an application of omega-3 and/or omega-6 fatty acid(s) for the therapeutic treatment of the human or animal body in the case of an impaired sphingolipid metabolism, in particular in the case of impaired sphingolipid synthesis and/or excessive sphingolipid degradation. In an embodiment of the invention, the agent is applied in the case of missing, reduced and/or defective formation of a sphingomyelin synthase enzyme in the body, in particular the enzyme sphingomyelin synthase 1 or the enzyme sphingomyelin synthase 2. The application has proved to be useful in the case of a defect of the sphingomyelin synthase 1 gene or of the sphingomyelin synthase 2 gene. The omega-3 and/or omega-6 fatty acid(s) preferably comprise(s) polyunsaturated omega-3 and/or omega-6 fatty acid(s), preferably EPA, DHA, DPA, ETA, 21:5n3 and/or SDA. The invention further relates to a method for determining a cause of a disease in an animal or a human being and to a device for carrying out the method.
A61P 15/08 - Drugs for genital or sexual disordersContraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
G01N 33/00 - Investigating or analysing materials by specific methods not covered by groups
05 - Pharmaceutical, veterinary and sanitary products
29 - Meat, dairy products, prepared or preserved foods
30 - Basic staples, tea, coffee, baked goods and confectionery
Goods & Services
Dietary supplements and food supplements; Dietetic substances and foods adapted for medical and veterinary use. Dietetic oils and greases, including being primary products used in industry; Edible oils and fats, and oils and greases for manufacturing edible oils and fats; Margarine and other fat-containing mixtures for bread slices; Sauces consisting predominantly of edible oils and fats; Meat, fish, poultry and game products; Meat extracts; Meat; Preserves and cooked fruits and vegetables; Canned mushrooms; Jellies; Marmalade; Egg products; Milk products; Potato chips. Cocoa products; Flour; bread and pastry products, Including only prebaked, Confectioneries, Puddings; Edible ices; Powders for ice cream; Ice cream (Binding agents for -); Mustard; Sauces (condiments); Sausage binding materials; Pasties; Fruit sauces.
29.
PHYTANIC ACID FRACTIONATION PROCESS, FATTY ACID PRODUCTS AND USE THEREOF
The present invention relates to a concentration- and purification method for compositions containing phytanic acid and/or derivatives thereof besides other fatty acids and/or their derivatives, preferably besides polyunsaturated fatty acids and/or their derivatives, such as esters or salts. With the fractionation process the phytanic acid (derivative) can become concentrated and the fatty acid mixture, preferably PUFA-mixture, can be purified from this particular component.
2, wherein in the said method, during the run of the said mixture on the chromatographic column, a pressure and/or temperature gradient is applied to the chromatographic column during the elution of the target fatty acid or derivative thereof.
42 - Scientific, technological and industrial services, research and design
Goods & Services
Research and development in the field of lipid extraction from natural sources; laboratory services namely, extraction of lipids and other by-products from fish oil and plants for others and manufacture of pharmaceutical and nutraceutical preparations containing Omega-3 extracts in the form of oils, powders and capsules for others.
42 - Scientific, technological and industrial services, research and design
Goods & Services
Research and development in the field of lipid extraction from natural sources; laboratory services namely, extraction of lipids and other by-products from fish oil and plants for others and manufacture of pharmaceutical and nutraceutical preparations containing Omega-3 extracts in the form of fish oils, powders and capsules for others.
40 - Treatment of materials; recycling, air and water treatment,
Goods & Services
Extraction of lipids and other by-products from fish oil and plants for others; manufacture of pharmaceutical and neutraceutical preparations containing Omega-3 extracts in the form of oils, powders and capsules for others
The invention relates to the use of omega-3-fatty acid(s) in means for pain relief. Said means preferably comprise highly unsaturated omega-3-fatty acid(s) that contain, above all, EPA and/or DHA. Preferably, the omega-3-fatty acid is administered in a high dose of more than 2g, in particular more than 3 to 4g for pain relief.
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
The invention relates to the use of omega-3-fatty acid(s) in means for pain relief. Said means preferably comprise highly unsaturated omega-3-fatty acid(s) that contain, above all, EPA and/or DHA. Preferably, the omega-3-fatty acid is administered in a high dose of more than 2g, in particular more than 3 to 4g, for pain relief.
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
36.
IMPROVED CHROMATOGRAPHY PROCESS FOR RECOVERING A SUBSTANCE OR A GROUP OF SUBSTANCES FROM A MIXTURE
Method for improving the performance of a preparative batchwise Super Critical Fluid Chromatographic separation for the recovery of a target fatty acid or derivative thereof, or of a group of target fatty acids or of derivatives thereof from a mixture, characterized in that the said Super Critical Fluid Chromatographic separation employs a chromatographic column charged with a stationary phase chosen from the group consisting of aluminium oxide or aluminium oxides, titanium oxide or titanium oxides, silica gel or silica gels, amino propyl modified silica gels, diol modified silica gels, phenyl modified silica gels and "reversed phase" phases, the former in turn chosen from the group consisting of RP 18, RP8 and RP3, and in that the said Super Critical Fluid Chromatographic Separation further employs a mobile phase chosen from the group consisting of ethylene, propane, ammonia, dinitrogen dioxide and CO2, wherein in the said method, during the run of the said mixture on the chromatographic column, a pressure and/or temperature gradient is applied to the chromatographic column during the elution of the target fatty acid or derivative thereof.
B01D 15/16 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
B01D 15/40 - Selective adsorption, e.g. chromatography characterised by the separation mechanism using supercritical fluid as mobile phase or eluent
G01N 30/28 - Control of physical parameters of the fluid carrier
37.
IMPROVED CROMATOGRAPHY PROCESS FOR RECOVERING A SUBSTANCE OR A GROUP OF SUBSTANCES FROM A MIXTURE
Method for improving the performance of a preparative batchwise Super Critical Fluid Chromatographic separation for the recovery of a target fatty acid or derivative thereof, or of a group of target fatty acids or of derivatives thereof from a mixture, characterized in that the said Super Critical Fluid Chromatographic separation employs a chromatographic column charged with a stationary phase chosen from the group consisting of aluminium oxide or aluminium oxides, titanium oxide or titanium oxides, silica gel or silica gels, amino propyl modified silica gels, diol modified silica gels, phenyl modified silica gels and 'reversed phase' phases, the former in turn chosen from the group consisting of RP 18, RP8 and RP3, and in that the said Super Critical Fluid Chromatographic Separation further employs a mobile phase chosen from the group consisting of ethylene, propane, ammonia, dinitrogen dioxide and CO2, wherein in the said method, during the run of the said mixture on the chromatographic column, a pressure and/or temperature gradient is applied to the chromatographic column during the elution of the target fatty acid or derivative thereof.
B01D 15/16 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
B01D 15/40 - Selective adsorption, e.g. chromatography characterised by the separation mechanism using supercritical fluid as mobile phase or eluent
G01N 30/28 - Control of physical parameters of the fluid carrier
