This disclosure relates generally to medical devices, systems, and methods for locating devices and/or anatomy during medical procedures. More particularly, in some embodiments, the disclosure relates to medical device and/or anatomy locating devices, access devices, and systems and methods thereof, for use during, e.g., gastrojejunostomy procedures. In an aspect, a medical device locator may include an elongate member (such as sheath or guidewire) having a proximal end, a distal end, a longitudinal axis, and a length extending along the longitudinal axis. A location device may be disposed along the length of the elongate member.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
A61B 1/06 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor with illuminating arrangements
A61B 1/273 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor for the upper alimentary canal, e.g. oesophagoscopes, gastroscopes
A61B 1/31 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor for the rectum, e.g. proctoscopes, sigmoidoscopes
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
2.
DISTAL TIPS OF MEDICAL DEVICES AND RELATED METHODS
Medical devices and related methods are described, including a medical device that includes a shaft including a working channel and a distal tip. The distal tip may include an assembly that includes an imaging device and an elevator. The assembly may be movable from a lowered configuration to an angled configuration to move the imaging device and the elevator from the lowered configuration to the angled configuration.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
Locking catheters including a fluid-tight hub and mechanism to secure a flexible member. An illustrative locking catheter may comprise an elongate shaft defining a lumen, a first connection member coupled to the elongate shaft, a second connection member configured to be releasably coupled to the first connection member, and a flexible member extending through at least a portion of a lumen of the elongate shaft and a portion of a lumen of the first connection member. The proximal end of the flexible member may extend through the aperture of the first connection member such that the proximal end of the flexible member is exterior to the first connection member. When the second connection member is coupled with the first connection member, the flexible member may be secured between an inner surface of the first connection member and an outer surface of the inner tubular member of the second connection member.
In some aspects, the present invention provides surgical procedures that comprise applying compositions into and/or onto tissue, including supporting tissues (e.g., ligaments, connective tissue, muscles, etc.) for pelvic organs, among other tissues. In other aspects, the present disclosure pertains to compositions that are useful for performing such procedures. In still other aspects, the present disclosure pertains to kits that are useful for performing such procedures.
According to exemplary embodiments of the present disclosure, devices, systems, and methods for pyloric occlusion in an endoscopic procedure may include a first flange and a second flange connected to the first flange by a saddle region having a lumen. The second flange may be proximal to the first flange. The pyloric occlusion device may further include a closure element. The closure element may be configured to occlude a flow of material through the lumen, including across the pylorus when deployed. The closure element may be a closure of the lumen by rotation of one of the first or second flanges about the saddle region relative to the other of the first or second flange.
A61F 2/04 - Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
A61B 1/018 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor characterised by internal passages or accessories therefor for receiving instruments
A61B 1/273 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor for the upper alimentary canal, e.g. oesophagoscopes, gastroscopes
A61B 5/06 - Devices, other than using radiation, for detecting or locating foreign bodies
A61B 17/00 - Surgical instruments, devices or methods
A61B 17/11 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for performing anastomosisButtons for anastomosis
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/29 - Forceps for use in minimally invasive surgery
A61B 17/30 - Surgical pincettes, i.e. surgical tweezers
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
A61B 90/30 - Devices for illuminating a surgical field, the devices having an interrelation with other surgical devices or with a surgical procedure
A61F 5/00 - Orthopaedic methods or devices for non-surgical treatment of bones or jointsNursing devices
A61M 25/01 - Introducing, guiding, advancing, emplacing or holding catheters
6.
REACTIVE POLYMERS AND HYDROGELS FORMED FROM THE SAME
In some aspects, the present disclosure provides reactive polymers that comprise one or more hydrophilic polymer segments having a plurality of hydrophilic polymer segment ends and a plurality of reactive moieties covalently linked to at least a portion of the hydrophilic polymer segment ends. The reactive moieties are 3,4-substituted-2,5-pyrrolidinedione moieties in which the 3-carbon and the 4-carbon form part of at least one ring in addition to the 2,5-pyrrolidinedione ring, and the 2,5-pyrrolidinedione ring nitrogen atom of each of the 3,4-substituted-2,5-pyrrolidinedione moieties is linked to one of the hydrophilic polymer segment ends. In other aspects, the present disclosure provides systems for forming hydrogel compositions and methods of treatment that employ such reactive polymers and methods of synthesizing such reactive polymers.
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
C08G 65/332 - Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides or esters thereof
C08G 65/333 - Polymers modified by chemical after-treatment with organic compounds containing nitrogen
Locking catheter (10) including a fluid-tight hub (16) comprises an elongate shaft (12) defining a lumen, a first connection member (36) coupled to the shaft, a second connection member (30) configured to be releasably coupled to the first connection member, and a flexible member (14) extending through at least a portion of a lumen of the elongate shaft (12) and a portion of a lumen of the first connection member (36). The proximal end of the flexible member (14) extends through an aperture (52) of the first connection member such that the proximal end of the flexible member is exterior to the first connection member. When the second connection member (30) is coupled with the first connection member, the flexible member (14) is secured between an inner surface of the first connection member (36) and an outer surface of an inner tubular member (74) of the second connection member.
A left atrial appendage closure device adapted for occluding the left atrial appendage includes a cone-shaped insert formed of an expandable foam and adapted for trans-septal delivery to the LAA. A polymeric covering is disposed over the cone-shaped insert, the polymeric covering adapted to protect the cone-shaped insert during trans-septal delivery to the LAA, the polymeric covering adapted for removal after trans-septal delivery to the LAA. An insert lumen extends through the cone-shaped insert prior to expansion of the cone-shaped insert. A tubular support rod extends through the insert lumen, the tubular support rod operably coupled with at least a portion of the polymeric covering, the tubular support rod itself defining a tubular support rod lumen adapted to accommodate a guidewire over which the insert may be advanced into the LAA and/or a radio frequency (RF) energy wire adapted for making a trans-septal puncture.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/00 - Surgical instruments, devices or methods
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
9.
MEDICAL DEVICES AND RELATED SYSTEMS AND METHODS FOR REDUCING SIGNAL DISTORTION IN IMAGE SIGNALS
According to one aspect, a medical device system for visualizing internal patient anatomy may comprise: a shaft including a distal tip portion, the tip portion including an imaging device, and a signal modulator; and a control unit operatively coupled to the shaft and including a de-modulator. The imaging device may be configured to output a first signal to the signal modulator. The signal modulator may be configured to modulate the received first signal and output a modulated second signal to the control unit; and the de-modulator of the control unit may be configured to receive the modulated second signal, de-modulate the second signal, and output a de-modulated third signal. The control unit may be configured to output the de-modulated third signal to an electronic display.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
10.
CROSSLINKING AGENTS AND MEDICAL HYDROGELS FORMED THEREFROM
In some aspects, the present disclosure pertains to methods that comprise (a) performing a ring-opening polymerization of one or more types of amino acid N-carboxyanhydride (NCA) monomers that comprise at least one type of protected amino acid NCA monomer having a protected pendant amine group in the presence of an initiator compound to produce intermediate peptide compounds that comprise an amino acid chain having protected pendant amine groups covalently attached to a residue of the initiator and (b) deprotecting the intermediate peptide compounds to form final peptide compounds that comprise an amino acid chain having pendant amine groups covalently attached to the residue of the initiator.
C07K 5/09 - Tripeptides the side chain of the first amino acid containing more amino groups than carboxyl groups, or derivatives thereof, e.g. Lys, Arg
11.
MEDICAL DEVICES AND RELATED SYSTEMS AND METHODS FOR REDUCING SIGNAL DISTORTION IN IMAGE SIGNALS
According to one aspect, a medical device system for visualizing internal patient anatomy may comprise: a shaft including a distal tip portion, the tip portion including an imaging device, and a signal modulator; and a control unit operatively coupled to the shaft and including a de-modulator. The imaging device may be configured to output a first signal to the signal modulator. The signal modulator may be configured to modulate the received first signal and output a modulated second signal to the control unit; and the de-modulator of the control unit may be configured to receive the modulated second signal, de-modulate the second signal, and output a de-modulated third signal. The control unit may be configured to output the de-modulated third signal to an electronic display.
H04N 23/80 - Camera processing pipelinesComponents thereof
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
Polymer microspheres containing poly-lactide-co-glycolide (PLGA) and therapeutic agent are described. Also described are methods of making such polymer microspheres and methods of using such polymer microspheres for embolizing blood vessels.
Example ultrasound medical devices are disclosed. An example medical device includes a support member having a proximal end region and a distal end region and a sensing member having a proximal end region and a distal end region, the distal end region of the sensing member coupled to the distal end region of the support member. The medical device also includes one or more ultrasound sensors disposed along the sensing member and a support shaft having a first end coupled to the sensing member and a second end coupled to the support member. Additionally, the sensing member is configured to shift from a first configuration in which the sensing member is adjacent to the support member to a second configuration in which at least a portion of the sensing member extends away from the support member.
A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
A61B 1/307 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor for the urinary organs, e.g. urethroscopes, cystoscopes
A catheter for an ultrasound system can a marker disposed on the hub. The marker is optically or magnetically readable and, when read, identifies the catheter. A drive unit can include an optical or magnetic marker reader. Alternatively or additionally, a catheter may include an active memory arrangement that can be read by an appropriate reader on the drive unit.
Medical devices and related methods are described, including a medical device(100) that includes a shaft (118) including a working channel and a distal tip (220). The distal tip may include an assembly (352) that includes an imaging device (322) and an elevator (326). The assembly may be movable from a lowered configuration to an angled configuration to move the imaging device and the elevator from the lowered configuration to the angled configuration.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
A61B 1/05 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor combined with photographic or television appliances characterised by the image sensor, e.g. camera, being in the distal end portion
A61B 1/06 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor with illuminating arrangements
16.
REACTIVE POLYMERS AND HYDROGELS FORMED FROM THE SAME
In some aspects, the present disclosure provides reactive polymers that comprise one or more hydrophilic polymer segments having a plurality of hydrophilic polymer segment ends and a plurality of reactive moieties covalently linked to at least a portion of the hydrophilic polymer segment ends. The reactive moieties are 3,4-substituted-2,5-pyrrolidinedione moieties in which the 3-carbon and the 4-carbon form part of at least one ring in addition to the 2,5-pyrrolidinedione ring, and the 2,5-pyrrolidinedione ring nitrogen atom of each of the 3,4-substituted-2,5-pyrrolidinedione moieties is linked to one of the hydrophilic polymer segment ends. In other aspects, the present disclosure provides systems for forming hydrogel compositions and methods of treatment that employ such reactive polymers and methods of synthesizing such reactive polymers.
C08L 101/14 - Compositions of unspecified macromolecular compounds characterised by physical features, e.g. anisotropy, viscosity or electrical conductivity the macromolecular compounds being water soluble or water swellable, e.g. aqueous gels
C08G 65/26 - Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
A pigtail catheter may include an elongate shaft having a curled distal tip, a tubular sheath slidably disposed over the elongate shaft, and a compliant expandable member fixed to the elongate shaft and the tubular sheath. A transcatheter aortic valve replacement (TAVR) system may include the pigtail catheter, a TAVR delivery device comprising an elongate shaft having an implant holding portion proximate a distal end thereof, and a TAVR implant disposed within the holding portion in a collapsed configuration, the TAVR implant comprising an expandable framework including a lower crown disposed at an upstream end and an upper crown disposed downstream of the lower crown. The compliant expandable member is configured to identify a downstream extent of a surgical aortic valve implant disposed within an ascending aorta prior to deploying the TAVR implant.
Medical device system for ablating cardiac tissue comprising a pulsed electric field power source in the nature of a pulse generator, an ablation catheter, a catheter delivery system, a deflectable sheath, and instruction manuals provided as a unit
An illustrative stent includes an elongated tubular member comprising at least one strut forming a tubular wall having a plurality of cells extending through a thickness of the tubular wall. The elongated tubular member may be configured to move between a radially collapsed configuration and a radially expanded configuration. A coating may be disposed on the elongated tubular member and spanning at least some of the plurality of cells. One or more magnetic components may be disposed on or within the coating.
A medical device for causing blood flow within a left atrial appendage (LAA) includes a flow energy capture element adapted to capture energy caused by movement within the heart. A transmission element is operably coupled to the flow energy capture element, the transmission element adapted to utilize the captured energy to cause blood flow within the LAA.
A61M 60/882 - Devices powered by the patient, e.g. skeletal muscle powered devices
A61M 60/187 - Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient’s body implantable in, on, or around the heart mechanically acting upon the inside of the patient’s native heart, e.g. contractile structures placed inside the heart
A61M 60/289 - Devices for mechanical circulatory actuation assisting the residual heart function by means mechanically acting upon the patient's native heart or blood vessel structure, e.g. direct cardiac compression [DCC] devices
A61M 60/47 - Details relating to driving for devices for mechanical circulatory actuation the force acting on the actuation means being mechanical, e.g. mechanically driven members clamping a blood vessel
A61M 60/492 - Details relating to driving for devices for mechanical circulatory actuation the force acting on the actuation means being magnetic generated by permanent magnets
A61M 60/839 - Constructional details other than related to driving of devices for mechanical circulatory actuation
A61M 60/861 - Connections or anchorings for connecting or anchoring pumps or pumping devices to parts of the patient’s body
Delivery devices for an occlusive implant and method for making and using delivery devices are disclosed. An example delivery device may include a delivery sheath having a proximal region, a garage region, and a distal tip region. The proximal region may have a proximal inner diameter. The garage region may have a garage inner diameter larger than the proximal inner diameter. A reinforcing member may extend along the proximal region, the garage region, or both. A core member may be slidably disposed within the delivery sheath. An occlusive implant releasably coupled to the core member.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
23.
EXPANDING FOAM DELIVERY SYSTEM FOR OCCLUDING LEFT ATRIAL APPENDAGE
A left atrial appendage closure device adapted for occluding the left atrial appendage includes a cone-shaped insert formed of an expandable foam and adapted for trans-septal delivery to the LAA. A polymeric covering is disposed over the cone-shaped insert, the polymeric covering adapted to protect the cone-shaped insert during trans-septal delivery to the LAA, the polymeric covering adapted for removal after trans-septal delivery to the LAA. An insert lumen extends through the cone-shaped insert prior to expansion of the cone-shaped insert. A tubular support rod extends through the insert lumen, the tubular support rod operably coupled with at least a portion of the polymeric covering, the tubular support rod itself defining a tubular support rod lumen adapted to accommodate a guidewire over which the insert may be advanced into the LAA and/or a radio frequency (RF) energy wire adapted for making a trans-septal puncture.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/00 - Surgical instruments, devices or methods
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A bipolar ablation device for treatment of a stenosis within an implanted metallic stent may include an elongate shaft slidably disposable within an endoscope, the elongate shaft including at least one electrode configured to form a first pole of the bipolar ablation device, and an electrode lead slidably disposable within the endoscope. The electrode lead may be configured to electrically engage the implanted metallic stent to form a second pole of the bipolar ablation device. The elongate shaft may be positionable within a lumen of the implanted metallic stent.
A61B 17/00 - Surgical instruments, devices or methods
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A61B 18/12 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
25.
ULTRASOUND IMAGING AND BACKSCATTER SYSTEM AND METHOD
An ultrasound imaging and backscatter system comprises an ICE ultrasonic catheter having an ultrasonic pMUT transducer array disposed within a distal end of the ultrasonic catheter, and comprises a plurality of transducer array elements arranged on a substrate. A catheter shaft is connected at one end to a handle assembly and at other end to the ultrasonic transducer array. The catheter shaft houses an electronic flex cable which is in communication with a signal trace, and directs each of the plurality of transducer array elements to transmit and receive ultrasound beams, receive at least one signal from the plurality of transducer array elements, and construct at least one image characterizing one or more tissue component of a scanned object. The ultrasound imaging system is used for measuring tissue thickness, tissue scarring and lesion assessment for left and right atrium and ventricle tissue wall characterization and other intracardiac tissue abnormalities.
B06B 1/06 - Processes or apparatus for generating mechanical vibrations of infrasonic, sonic or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction
An illustrative stent includes an elongated tubular member comprising at least one strut forming a tubular wall having a plurality of cells extending through a thickness of the tubular wall. The elongated tubular member may be configured to move between a radially collapsed configuration and a radially expanded configuration. A coating may be disposed on the elongated tubular member and spanning at least some of the plurality of cells. One or more magnetic components may be disposed on or within the coating.
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
Medical devices and related methods are discussed, including a medical device that includes a handle with a housing and an actuator mechanism disposed within the housing. The actuator mechanism may include a biasing member and a disk rotatable between a first position and a second position, e.g., the biasing member having a first length and exerting a first distal force on the disk in the first position, and having a second length different from the first length and exerting a second distal force on the disk less than the first distal force in the second position.
A medical stent includes a central stent segment, a proximal stent segment adapted to be positioned over a proximal region of the central stent segment, and a distal stent segment adapted to be positioned over a distal region of the central stent segment. A polymeric coating extends over the proximal stent segment, the distal stent segment and at least a portion of the central stent segment, the polymeric coating adapted to allow the proximal stent segment to float over the proximal region of the central stent segment and to allow the distal stent segment to float over the distal region of the central stent segment. Upon implantation, the central stent segment is adapted to translate relative to the proximal stent segment and the distal stent segment in response to peristaltic forces.
A61F 2/852 - Two or more distinct overlapping stents
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
29.
DEVICES, SYSTEMS, AND METHODS FOR DEPLOYING A TRANSCATHETER AORTIC VALVE IMPLANT WITHIN A SURGICAL AORTIC VALVE IMPLANT
A pigtail catheter may include an elongate shaft having a curled distal tip, a tubular sheath slidably disposed over the elongate shaft, and a compliant expandable member fixed to the elongate shaft and the tubular sheath. A transcatheter aortic valve replacement (TAVR) system may include the pigtail catheter, a TAVR delivery device comprising an elongate shaft having an implant holding portion proximate a distal end thereof, and a TAVR implant disposed within the holding portion in a collapsed configuration, the TAVR implant comprising an expandable framework including a lower crown disposed at an upstream end and an upper crown disposed downstream of 10 the lower crown. The compliant expandable member is configured to identify a downstream extent of a surgical aortic valve implant disposed within an ascending aorta prior to deploying the TAVR implant.
A device for treating tissue includes a clip including clip arms and a coupler. Each of the clip arms extends from a proximal end to a distal end. Proximal ends of the clip arms are slidably received within a channel of a capsule. A proximal end of the capsule includes openings extending through a wall. The coupler is mounted over the proximal end of the capsule via deployment arms including engaging features extending laterally inward from an interior surface thereof to engage the openings of the capsule. The coupler includes retention arms configured to engage a corresponding portion of an applicator. When a pre-determined compressive force is applied to the coupler, the deployment arms are proximally slidable along the corresponding portion of the applicator to deflect the deployment arms out of engagement with the capsule so that the coupler is separable from the capsule.
A61B 17/128 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord for applying or removing clamps or clips
A61B 17/00 - Surgical instruments, devices or methods
A61B 17/122 - Clamps or clips, e.g. for the umbilical cord
The present disclosure pertains to medical devices. More particularly, the present disclosure pertains to devices, systems, and methods for closing a wound, such as a tissue defect resulting from an endoscopic mucosal resection or endoscopic submucosal dissection procedure. In one example, a device for closing a wound may include a closure element having a delivery configuration and a deployed configuration, the closure element configured to be disposed about an endcap of an endoscope in a delivery configuration. A release filament may have a distal end releasably coupled to the closure element and a proximal end extendable within the endcap. The closure element may be configured to substantially close about the wound in the deployed configuration.
A61B 17/10 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for applying or removing wound clampsWound clamp magazines
A61B 17/00 - Surgical instruments, devices or methods
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A medical assembly may comprise an end effector; a sheath; and a device coupler. The device coupler may include a proximal support, a distal support, and a coupler arm extending between the proximal support and the distal support. The coupler arm may include a surface configured to accommodate a shape of a medical device resting upon the coupler arm. The end effector may be attached to the distal support, and the proximal support may be attached to the sheath.
A61B 17/00 - Surgical instruments, devices or methods
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
A61B 17/072 - Surgical staplers for applying a row of staples in a single action, e.g. the staples being applied simultaneously
A medical device includes a catheter shaft including a distal region and an inflatable balloon that is secured to the distal region of the catheter shaft. The inflatable balloon has an outer surface and defines a centerline when inflated. A blade extends over and is secured to the outer surface, the blade having a cutting edge extending from a distal end of the blade to a proximal end of the blade, when the inflatable balloon is inflated, the cutting edge extends to a maximum distance measured relative to the centerline of the inflatable balloon at the distal end of the blade and a minimum distance measured relative to the centerline of the inflatable balloon of the medical device at the proximal end of the blade.
Medical devices and related methods are discussed, including a medical device that includes a handle with a housing and an actuator mechanism disposed within the housing. The actuator mechanism may include a biasing member and a disk rotatable between a first position and a second position, e.g., the biasing member having a first length and exerting a first distal force on the disk in the first position, and having a second length different from the first length and exerting a second distal force on the disk less than the first distal force in the second position.
A medical stent includes a central stent segment, a proximal stent segment adapted to be positioned over a proximal region of the central stent segment, and a distal stent segment adapted to be positioned over a distal region of the central stent segment. A polymeric coating extends over the proximal stent segment, the distal stent segment and at least a portion of the central stent segment, the polymeric coating adapted to allow the proximal stent segment to float over the proximal region of the central stent segment and to allow the distal stent segment to float over the distal region of the central stent segment. Upon implantation, the central stent segment is adapted to translate relative to the proximal stent segment and the distal stent segment in response to peristaltic forces.
Delivery devices for an occlusive implant and method for making and using delivery devices are disclosed. An example delivery device may include a delivery sheath having a proximal region, a garage region, and a distal tip region. The proximal region may have a proximal inner diameter. The garage region may have a garage inner diameter larger than the proximal inner diameter. A reinforcing member may extend along the proximal region, the garage region, or both. A core member may be slidably disposed within the delivery sheath. An occlusive implant releasably coupled to the core member.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
Disclosed herein are radiopaque, reactive multi-arm polymers that comprise an iodine-containing core region, a plurality of polymer arms comprising a plurality of polymer segments linked to the iodine-containing core region, and a plurality of reactive moieties linked to the plurality of polymer segments. Also disclosed are methods of forming such radiopaque, reactive multi-arm polymers, systems for forming hydrogel compositions that comprise (a) such radiopaque, reactive multi-arm polymers and (b) multifunctional crosslinking compounds comprising a plurality of complementary reactive moieties that are reactive with the reactive moieties of the radiopaque, reactive multi-arm polymers, as well as reaction products of such systems and methods of treatment using such systems.
An implantable fluid operated device includes a fluid control system to transfer fluid between a fluid reservoir and an inflatable member. The fluid control system includes at least one fluid control device including at least one pump and at least one valve, or at least one combination pump and valve device. A seal is provided in the at least one fluid control device. In a first mode, the seal provides a seal between a fluid passageway and a fluid chamber of the fluid control device, to close the fluid control device. In a second mode, the seal is disengaged to open the fluid control device and allow fluid to flow between the fluid passageway and the fluid chamber. A seal retention device maintains a position of the seal when the fluid control device is open and fluid is flowing through the fluid control device.
A61F 2/48 - Operating or control means, e.g. from outside the body, control of sphincters
F16K 7/14 - Diaphragm cut-off apparatus, e.g. with a member deformed, but not moved bodily, to close the passage with flat, dished, or bowl-shaped diaphragm arranged to be deformed against a flat seat
BOSTON SCIENTIFIC MEDICAL DEVICE LIMITED (Ireland)
Inventor
Davis, Ryan Robert
Tomar, Peeyush
Rogers, Carly
Himes, Matthew D.
Verma, Aman Kumar
Abstract
A delivery system for an occlusive implant includes a delivery sheath assembly and a hub assembly. The delivery sheath assembly includes a delivery sheath defining a delivery lumen adapted to accommodate an occlusive implant releasably secured to a core wire. A proximal fitting is secured to the delivery sheath. The hub assembly includes a hub body, a distal hub secured relative to the hub body and adapted to engage the proximal fitting of the delivery sheath assembly, a proximal hub secured to the hub body, and a side port coupled to hub body and adapted for flushing an interior of the delivery system. The delivery system includes one or more features that are adapted to limit relative rotation between the delivery sheath assembly and the hub assembly when the core wire is rotationally locked to the proximal hub.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/00 - Surgical instruments, devices or methods
The present disclosure relates to the field of tissue dissection. Specifically, the present disclosure relates to medical devices which lift and retract tissue during a dissection procedure to improve visualization of the target tissue and mitigate obstruction of dissection tools. In particular, the present disclosure relates to a tissue retraction device which moves from a constrained to relaxed configuration to immobilize and retract the dissected portion of target tissue during a dissection procedure.
A system for treating tissue includes a capsule including a channel extending therethrough; first and second clip arms each extending from a proximal end to a distal end, the proximal ends being received within the channel of a capsule to be moved between an open tissue receiving configuration; and a closed tissue clipping configuration. The first clip arm includes a first tissue retention feature at a distal portion thereof configured to pierce through a target tissue when in the tissue clipping configuration and subsequently release the target tissue when the clip arms are moved to an at least partially open configuration. The second clip arm includes a second tissue retention feature at a distal portion thereof configured to pierce and retain the target tissue thereon when in both the closed tissue clipping configuration and the open tissue receiving configuration.
A61B 17/122 - Clamps or clips, e.g. for the umbilical cord
A61B 17/00 - Surgical instruments, devices or methods
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/128 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord for applying or removing clamps or clips
A medical device may comprise a distal tip having a viewing element, a lighting element, and at least one feature configured to removably couple the distal tip to a shaft. The medical device may also comprise a working channel coupled to the distal tip and defining a central lumen configured to receive a tool. A wall of the working channel may define at least one additional lumen. The working channel may be configured to be removably inserted into the shaft. The medical device may also comprise at least one of a wire, a cable, or a conduit passing through the at least one additional lumen.
A61B 1/018 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor characterised by internal passages or accessories therefor for receiving instruments
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
A61B 1/05 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor combined with photographic or television appliances characterised by the image sensor, e.g. camera, being in the distal end portion
A61B 1/06 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor with illuminating arrangements
43.
ELECTROANATOMICAL MAPPING DEVICE WITH INTERNAL ELECTRODE
A medical system for creating a communication channel between two anatomical structures includes an outer member having a proximal portion and a distal portion, and a lumen extending from the proximal portion to the distal portion. At least a portion of the lumen includes an electrically conductive surface extending to a distal end of the distal portion. The system includes an inner member having a proximal portion and a distal portion. The inner member is configured to translate within the lumen and to deliver a therapy to target tissue. The inner member distal portion includes a conductive distal tip configured to electrically couple with the electrically conductive surface of the outer member. The inner member includes a proximal portion adapted to electrically couple the conductive distal tip to an auxiliary device.
An implantable fluid operated device includes a fluid control system to transfer fluid between a fluid reservoir and an inflatable member. The fluid control system includes at least one fluid control device including at least one pump and at least one valve, or at least one combination pump and valve device. A seal is provided in the at least one fluid control device. In a first mode, the seal provides a seal between a fluid passageway and a fluid chamber of the fluid control device, to close the fluid control device. In a second mode, the seal is disengaged to open the fluid control device and allow fluid to flow between the fluid passageway and the fluid chamber. A seal retention device maintains a position of the seal when the fluid control device is open and fluid is flowing through the fluid control device.
Delivery devices for an occlusive implant and method for making and using delivery devices are disclosed. An example delivery device may include a delivery sheath having a sheath body and a distal tip region. A tip reinforcing member may be coupled to the distal tip region. The tip reinforcing member may define a plurality of distal arm segments. The distal arm segments are configured to shift between a first configuration and an expanded configuration. A core member may be slidably disposed within the delivery sheath. An occlusive implant may be releasably coupled to the core member.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
46.
BORONATED HYDROGELS AND METHODS OF MAKING AND USING THE SAME
This disclosure pertains to boronated hydrogel compositions, which comprise a boronated polysaccharide compound that comprises a plurality of boronated moieties covalently linked to a carboxylic-acid-containing polysaccharide along a backbone of the carboxylic-acid-containing polysaccharide. The disclosure also pertains to kits that comprise a reservoir, a boronated hydrogel composition comprising a boronated polysaccharide compound that comprises a plurality of boronated moieties covalently linked to a carboxylic-acid-containing polysaccharide along a backbone of the carboxylic-acid-containing polysaccharide disposed in the reservoir, and a device for administering the boronated hydrogel composition to a subject. The disclosure further pertains to methods of treatment that comprise applying or injecting a boronated hydrogel composition comprising a boronated polysaccharide compound that comprises a plurality of boronated moieties covalently linked to a carboxylic-acid-containing polysaccharide along a backbone of the carboxylic-acid-containing polysaccharide onto or into target cells of a subject and delivering neutron beam radiation to the target cells.
The present disclosure pertains to systems for forming hydrogel compositions that comprise a reactive polymer comprising a plurality of hydrophilic polymer segments and a plurality of first reactive moieties and gold nanoparticles, wherein the system is configured to deliver the reactive polymer and the gold nanoparticles under conditions such that covalent crosslinks are formed between the reactive polymer and the gold nanoparticles. The present disclosure also pertains to methods of treatment that comprise administering to a subject a mixture that comprises a reactive polymer comprising a plurality of hydrophilic polymer segments and a plurality of first reactive moieties and gold nanoparticles, under conditions such that the reactive polymer and the gold nanoparticles crosslink after administration, and to radiopaque crosslinked hydrogel compositions that comprise a crosslinked reaction product of a reactive polymer comprising a plurality of hydrophilic polymer segments and a plurality of first reactive moieties and gold nanoparticles.
Delivery devices for an occlusive implant and method for making and using delivery devices are disclosed. An example delivery device may include a delivery sheath having a sheath body and a distal tip region. A tip reinforcing member may be coupled to the distal tip region. The tip reinforcing member may define a plurality of distal arm segments. The distal arm segments are configured to shift between a first configuration and an expanded configuration. A core member may be slidably disposed within the delivery sheath. An occlusive implant may be releasably coupled to the core member.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/00 - Surgical instruments, devices or methods
A medical device includes a catheter shaft including a distal region and an inflatable balloon that is secured to the distal region of the catheter shaft. The inflatable balloon has an outer surface and defines a centerline when inflated. A blade extends over and is secured to the outer surface, the blade having a cutting edge extending from a distal end of the blade to a proximal end of the blade, when the inflatable balloon is inflated, the cutting edge extends to a maximum distance measured relative to the centerline of the inflatable balloon at the distal end of the blade and a minimum distance measured relative to the centerline of the inflatable balloon of the medical device at the proximal end of the blade.
A method is provided for enhancing video images in a medical device. The method includes receiving a first image frame and a second image frame from one or more image sensors. The first image sub-blocks are generated by dividing the first image frame. At least one curve to the first image sub-blocks are associated based on one or more look-up tables. A target in at least one of the first image sub-blocks is identified. Second image sub-blocks are generated by dividing the second image frame. At least one curve is associated to the second image sub-blocks based on the one or more look-up tables. The target is identified in at least one of the second image sub-blocks. Histogram enhanced images of the target in the first image sub-blocks and the second image sub-blocks are generated. A video image stream is generated based on the histogram enhanced images of the target.
G06T 3/4069 - Scaling of whole images or parts thereof, e.g. expanding or contracting based on super-resolution, i.e. the output image resolution being higher than the sensor resolution by subpixel displacements
G06T 5/40 - Image enhancement or restoration using histogram techniques
G06V 10/50 - Extraction of image or video features by performing operations within image blocksExtraction of image or video features by using histograms, e.g. histogram of oriented gradients [HoG]Extraction of image or video features by summing image-intensity valuesProjection analysis
A linkage assembly for a medical device may comprise: a rotatable member configured to rotate about a rotation axis; a piston; and a connecting rod rotatably connected to the rotatable member and the piston and movable along a range. A first end of the range may correspond to an initial position of a distal member movable by the linkage assembly, and a second end of the range may correspond to a final position of a distal member. In a first configuration of the connecting rod, at the first end of the range, a proximal end of the connecting rod may be offset from a longitudinal axis by a first amount. In a second configuration of the connecting rod, at the second end of the range, the proximal end of the connecting rod may be offset from the longitudinal axis by a second amount.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
Devices, systems, and methods for deploying a biliary stent. A biliary stent has lobes and creases to expand between contracted and expanded positions. The stent is delivered to a bile duct in a contracted position loaded on a shaft of a delivery device. When the shaft is retracted through the stent, wings on the shaft force the stent outward into the larger expanded position. In the expanded position, the creases form drainage channels to reduce blockage over the life of the stent.
BOSTON SCIENTIFIC MEDICAL DEVICE LIMITED (Ireland)
Inventor
Davis, Ryan, Robert
Tomar, Peeyush
Rogers, Carly
Himes, Matthew, D.
Verma, Aman, Kumar
Abstract
A delivery system for an occlusive implant includes a delivery sheath assembly and a hub assembly. The delivery sheath assembly includes a delivery sheath defining a delivery lumen adapted to accommodate an occlusive implant releasably secured to a core wire. A proximal fitting is secured to the delivery sheath. The hub assembly includes a hub body, a distal hub secured relative to the hub body and adapted to engage the proximal fitting of the delivery sheath assembly, a proximal hub secured to the hub body, and a side port coupled to hub body and adapted for flushing an interior of the delivery system. The delivery system includes one or more features that are adapted to limit relative rotation between the delivery sheath assembly and the hub assembly when the core wire is rotationally locked to the proximal hub.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
An implantable fluid operated device includes a fluid control system to transfer fluid between a fluid reservoir and an inflatable member. The fluid control system includes at least one fluid control device including at least one pump and at least one valve, or at least one combination pump and valve device. The at least one fluid control device includes an auxiliary fluid control device that maintains a closed state of the valve in response to a fluctuation in pressure, or a pressure spike that would otherwise cause an unintentional opening of the fluid control device, and unintentional flow of fluid through the fluid control device.
A medical device may comprise a tube including: a proximal portion; and a distal portion having a slotted section with a plurality of slots formed therein. A proximalmost slot of the plurality of slots may have a first length in a circumferential direction about the tube. A distalmost slot of the plurality of slots may have a second length in the circumferential direction about the tube. The first length may be smaller than the second length. The medical device may further comprise a hub coupled to a proximal portion of the tube. Rotation of the hub may be configured to rotate the proximal portion of the tube about a longitudinal axis of the proximal portion of the tube.
An actuation mechanism for a medical device comprises: a rotatable member configured to rotate about a rotational axis and a spring, coupled directly or indirectly to the rotatable member. The spring is configured to move from a first configuration to a second configuration. In the first configuration, a longitudinal axis of the spring has a first angle with respect to a lever arm of the rotatable member. In the second configuration, a longitudinal axis of the spring has a second angle with respect to the lever arm of the rotatable member.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
A polymeric material having a polyisobutylene polyurethane. The polyisobutylene having soft segments including a polyisobutylene diamine residue, and hard segments including bis-cyclic carbonate residue.
C08L 23/22 - Copolymers of isobuteneButyl rubberHomopolymers or copolymers of other iso-olefins
C08L 23/36 - Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bondCompositions of derivatives of such polymers modified by chemical after-treatment by reaction with nitrogen-containing compounds, e.g. by nitration
58.
MULTI-ELECTRODE DEVICES, SYSTEMS, AND METHODS FOR MEDICAL PROCEDURES
A multi-electrode energy-delivering assembly configured to be delivered in a generally elongate delivery configuration. The multi-electrode energy-delivering assembly includes one or more spaced apart electrodes of a first polarity. The electrodes may be spaced apart axially and/or may be expanded apart from one another upon deployment. In some aspects, the electrodes may be electrically activated independently of one another.
A medical system for creating a communication channel between two anatomical structures includes an outer member having a proximal portion and a distal portion, and a lumen extending from the proximal portion to the distal portion. At least a portion of the lumen includes an electrically conductive surface extending to a distal end of the distal portion. The system includes an inner member having a proximal portion and a distal portion. The inner member is configured to translate within the lumen and to deliver a therapy to target tissue. The inner member distal portion includes a conductive distal tip configured to electrically couple with the electrically conductive surface of the outer member. The inner member includes a proximal portion adapted to electrically couple the conductive distal tip to an auxiliary device.
A medical device includes a shaft and a braided sheath. The braided sheath is coaxial with the shaft and at least extends along the shaft between a distal end of the shaft and a proximal end of the shaft. The braided sheath includes a braiding. The braiding includes a plurality of mechanical strands and at least one conductor configured to deliver energy to or convey signals to and from an electrical device positioned at or near the distal end of the shaft.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
A61B 1/018 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor characterised by internal passages or accessories therefor for receiving instruments
61.
MEDICAL OPTICAL FIBER WITH INTRA-PROCEDURE RENEWABLE TIP
The present disclosure provides a medical optical fiber comprising a renewable distal end. The renewable distal end comprising several detachable segments where the detachable segments can be selectively and/or automatically detached to renew the distal most tip of the optical fiber.
A61B 18/26 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibreHand-pieces therefor for producing a shock wave, e.g. laser lithotripsy
A61B 18/22 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibreHand-pieces therefor
62.
ENDOLUMINAL SEALING DEVICES AND RELATED METHODS OF USE
A medical system includes a porous body positioned at a target site within a subject, a tube including a wall defining a tube lumen, where the tube is connected to the porous body at a first end of the tube, and a sealing device to seal the target site from a body lumen. When the sealing device seals the target site from the body lumen, the tube extends from the target site into the body lumen.
A61M 1/00 - Suction or pumping devices for medical purposesDevices for carrying-off, for treatment of, or for carrying-over, body-liquidsDrainage systems
A61B 17/00 - Surgical instruments, devices or methods
A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
A61F 2/04 - Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
63.
Apparatus and Methodology for Reshaping a Laser Beam
A laser system may include a laser resonator configured to emit an input laser beam having an elliptical cross-sectional shape. The laser system also may include first reflective device configured to reflect the input laser beam to produce a first reflected laser beam. The first reflective device may include a spherical surface for reflecting the input laser beam. The laser system also may include a second reflective device configured to reflect the first reflected laser beam to produce a second reflected laser beam. The laser system also may include a coupling device configured to focus the second reflected laser beam to produce an output laser beam. The coupling device may include a spherical surface for receiving the second reflected laser beam. The laser system also may include an optic fiber configured to transmit the output laser beam for emission of the output laser beam onto a target area.
Example medical stents are disclosed. An example stent includes a tubular framework including an inner surface, an outer surface and a lumen extending therethrough. Additionally, the stent includes a tissue ingrowth scaffold extending along a portion of the outer surface of the tubular framework, wherein the tissue ingrowth scaffold is spaced radially away from the outer surface of the tubular framework to define an expansion cavity therebetween and wherein the tissue ingrowth scaffold permits tissue ingrowth along a portion thereof. Further, the stent includes an expandable member positioned within at least a portion of the expansion cavity.
A61F 2/90 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
A61F 2/844 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents folded prior to deployment
A61F 2/848 - Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents having means for fixation to the vessel wall, e.g. barbs
A61F 2/88 - Stents in a form characterised by wire-like elementsStents in a form characterised by a net-like or mesh-like structure the wire-like elements formed as helical or spiral coils
A61F 2/92 - Stents in the form of a rolled-up sheet expanding after insertion into the vessel
A61F 2/95 - Instruments specially adapted for placement or removal of stents or stent-grafts
Devices, systems, and methods for a two-way valve assembly for a medical device. The two-way valve assembly has a knob seated within a valve body, two inlet passages leading to a suction source and a gas source, an outlet passage leading to an endoscope fluid channel, and an internal channel connecting one of the two inlet passages to the outlet passage. A spring presses the knob into the valve body to seal the openings along the channels and passages. Rotating the knob slides one or more guide pins on the knob along one or more guide grooves on the body and connects the other inlet passage to the outlet passage, such that the same endoscope fluid channel can be used both for suction, as in clearing fluid from within a patient, and delivering gas, as in insufflation.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
A61B 1/015 - Control of fluid supply or evacuation
An actuation mechanism for a medical device comprises: a rotatable member configured to rotate about a rotational axis and a spring, coupled directly or indirectly to the rotatable member. The spring is configured to move from a first configuration to a second configuration. In the first configuration, a longitudinal axis of the spring has a first angle with respect to a lever arm of the rotatable member. In the second configuration, a longitudinal axis of the spring has a second angle with respect to the lever arm of the rotatable member.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
An implantable fluid operated device may include a fluid reservoir configured to hold fluid, an inflatable member, and an electronic fluid control system to transfer fluid between the fluid reservoir and the inflatable member. The fluid control system includes at least one combination pump and valve device including a piezoelectric actuator.
A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
An implantable fluid operated device includes a fluid control system to transfer fluid between a fluid reservoir and an inflatable member. The fluid control system includes at least one fluid control device including at least one pump and at least one valve, or at least one combination pump and valve device. The at least one fluid control device includes an auxiliary fluid control device that maintains a closed state of the valve in response to a fluctuation in pressure, or a pressure spike that would otherwise cause an unintentional opening of the fluid control device, and unintentional flow of fluid through the fluid control device.
A61F 2/00 - Filters implantable into blood vesselsProstheses, i.e. artificial substitutes or replacements for parts of the bodyAppliances for connecting them with the bodyDevices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
A multi-electrode energy-delivering assembly configured to be delivered in a generally elongate delivery configuration. The multi-electrode energy-delivering assembly includes one or more spaced apart electrodes of a first polarity. The electrodes may be spaced apart axially and/or may be expanded apart from one another upon deployment. In some aspects, the electrodes may be electrically activated independently of one another.
Bipolar or monopolar adjustable energy-delivering assemblies. The assemblies are configured for transluminal (e.g., endoscopic) delivery within a patient. A first energy-delivering member defines a first electrode portion formed of an electrically-conductive material so that energy may be delivered to the first energy-delivering member to create an energy field along the first electrode portion to apply to a target site within a patient. The first energy-delivering member may define a lumen therethrough allowing delivery of materials distally therethrough to a target site and/or allows materials from the target site to be aspirated proximally therethrough. Optionally, a second energy-delivering member and a second insulation member form a second electrode portion. Optionally, either or both electrode portions may be adjustable. Additionally or alternatively, the first electrode portion and the second electrode portion are adjustable with respect to each other.
An energy-delivering treatment system facilitating determination of various characteristics of a lesion and/or tissue at a treatment site, such as the size and/or location of the lesion; stiffness and/or elasticity of the tissue; impedance or resistance of the tissue (which may impact the form of energy such as electroporation and/or irreversible electroporation applied to the tissue); and/or the effects of a treatment applied to the lesion. Information gathered regarding the treatment site may be used to aid in predicting and measuring lesions, and/or in determining an appropriate treatment plan on a patient-by-patient basis. Markers may be used to facilitate locating of the treatment site after the energy-delivering assembly has been withdrawn from the treatment site.
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
72.
DEVICES, SYSTEMS, AND METHODS FOR TUNNELING BETWEEN TISSUE LAYERS
An assembly and/or system having a cutting device configured to cut tissue, and an inflatable device configured for insertion into the cut tissue to further separate the cut tissue. The inflatable device may be wedge shaped to separate the cut tissue upon insertion into the cut. The inflatable device is inflatable and otherwise adjustable to separate the tissue to a medically indicated extent. For instance, the inflatable device may be moved axially with respect to the cutting device; and/or may be sheathed or unsheathed to adjust an exposed inflated length thereof; and/or may include two or more separately inflatable elements. The inflatable device thus may be used to achieve blunt tissue dissection after an initial cut is made into the tissue with a sharper instrument.
A medical device includes a shaft and a braided sheath. The braided sheath is coaxial with the shaft and at least extends along the shaft between a distal end of the shaft and a proximal end of the shaft. The braided sheath includes a braiding. The braiding includes a plurality of mechanical strands and at least one conductor configured to deliver energy to or convey signals to and from an electrical device positioned at or near the distal end of the shaft.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
The present disclosure pertains to systems for forming hydrogel compositions that comprise a reactive polymer comprising a plurality of hydrophilic polymer segments and a plurality of first reactive moieties and gold nanoparticles, wherein the system is configured to deliver the reactive polymer and the gold nanoparticles under conditions such that covalent crosslinks are formed between the reactive polymer and the gold nanoparticles. The present disclosure also pertains to methods of treatment that comprise administering to a subject a mixture that comprises a reactive polymer comprising a plurality of hydrophilic polymer segments and a plurality of first reactive moieties and gold nanoparticles, under conditions such that the reactive polymer and the gold nanoparticles crosslink after administration, and to radiopaque crosslinked hydrogel compositions that comprise a crosslinked reaction product of a reactive polymer comprising a plurality of hydrophilic polymer segments and a plurality of first reactive moieties and gold nanoparticles.
The present disclosure provides a medical optical fiber comprising a renewable distal end. The renewable distal end comprising several detachable segments where the detachable segments can be selectively and/or automatically detached to renew the distal most tip of the optical fiber.
A61B 18/22 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibreHand-pieces therefor
Devices, systems, and methods for a two-way valve assembly for a medical device. The two-way valve assembly has a knob seated within a valve body, two inlet passages leading to a suction source and a gas source, an outlet passage leading to an endoscope fluid channel, and an internal channel connecting one of the two inlet passages to the outlet passage. A spring presses the knob into the valve body to seal the openings along the channels and passages. Rotating the knob slides one or more guide pins on the knob along one or more guide grooves on the body and connects the other inlet passage to the outlet passage, such that the same endoscope fluid channel can be used both for suction, as in clearing fluid from within a patient, and delivering gas, as in insufflation.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
A61B 1/015 - Control of fluid supply or evacuation
A61B 1/267 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor for the respiratory tract, e.g. laryngoscopes, bronchoscopes
77.
MICRO-FLUIDIC DEVICE COMBINING FUNCTIONS OF A PUMP AND A VALVE
An implantable fluid operated device may include a fluid reservoir configured to hold fluid, an inflatable member, and an electronic fluid control system to transfer fluid between the fluid reservoir and the inflatable member. The fluid control system includes at least one combination pump and valve device including a piezoelectric actuator.
Bipolar or monopolar adjustable energy-delivering assemblies. The assemblies are configured for transluminal (e.g., endoscopic) delivery within a patient. A first energy-delivering member defines a first electrode portion formed of an electrically-conductive material so that energy may be delivered to the first energy-delivering member to create an energy field along the first electrode portion to apply to a target site within a patient. The first energy-delivering member may define a lumen therethrough allowing delivery of materials distally therethrough to a target site and/or allows materials from the target site to be aspirated proximally therethrough. Optionally, a second energy-delivering member and a second insulation member form a second electrode portion. Optionally, either or both electrode portions may be adjustable. Additionally or alternatively, the first electrode portion and the second electrode portion are adjustable with respect to each other.
An energy-delivering treatment system facilitating determination of various characteristics of a lesion and/or tissue at a treatment site, such as the size and/or location of the lesion; stiffness and/or elasticity of the tissue; impedance or resistance of the tissue (which may impact the form of energy such as electroporation and/or irreversible electroporation applied to the tissue); and/or the effects of a treatment applied to the lesion. Information gathered regarding the treatment site may be used to aid in predicting and measuring lesions, and/or in determining an appropriate treatment plan on a patient-by-patient basis. Markers may be used to facilitate locating of the treatment site after the energy-delivering assembly has been withdrawn from the treatment site.
A61B 5/055 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fieldsMeasuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
A61B 5/0536 - Impedance imaging, e.g. by tomography
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
80.
DEVICES, SYSTEMS, AND METHODS FOR TUNNELING BETWEEN TISSUE LAYERS
An assembly and/or system having a cutting device configured to cut tissue, and an inflatable device configured for insertion into the cut tissue to further separate the cut tissue. The inflatable device may be wedge shaped to separate the cut tissue upon insertion into the cut. The inflatable device is inflatable and otherwise adjustable to separate the tissue to a medically indicated extent. For instance, the inflatable device may be moved axially with respect to the cutting device; and/or may be sheathed or unsheathed to adjust an exposed inflated length thereof; and/or may include two or more separately inflatable elements. The inflatable device thus may be used to achieve blunt tissue dissection after an initial cut is made into the tissue with a sharper instrument.
Medical devices and related methods useful for needle access during medical procedures are described. The medical device may include a needle and a handle coupled to the needle, wherein the handle includes a body comprising a radiolucent material, a first marker proximate a proximal end of the body and a second marker proximate a distal end of the body. Each of the first marker and the second marker may include a radiopaque material, and the first marker may have a shape complementary to the second marker to align a position of the needle relative to a subject when visualized by X-ray imaging.
A61B 6/12 - Arrangements for detecting or locating foreign bodies
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
Devices, systems, and methods for deploying a biliary stent. A biliary stent has lobes and creases to expand between contracted and expanded positions. The stent is delivered to a bile duct in a contracted position loaded on a shaft of a delivery device. When the shaft is retracted through the stent, wings on the shaft force the stent outward into the larger expanded position. In the expanded position, the creases form drainage channels to reduce blockage over the life of the stent.
A61F 2/04 - Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
A61F 2/966 - Instruments specially adapted for placement or removal of stents or stent-grafts having an outer sleeve with relative longitudinal movement between outer sleeve and prosthesis, e.g. using a push rod
In some aspects, the present disclosure pertains to methods of treating a tissue volume comprising (a) administering an implantable composition comprising a releasable membrane-active agent to a target site such that the membrane-active agent is locally released to the tissue volume and (b) performing irreversible, reversible and/or thermal treatment by application of a pulsed electric field to the tissue volume. In other aspects, the present disclosure pertains to embolic compositions that comprise releasable membrane-active agents.
A medical device (10) may comprise a tube (118) including: a proximal portion; and a distal portion having a slotted section with a plurality of slots (122) formed therein. A proximalmost slot of the plurality of slots may have a first length in a circumferential direction about the tube. A distalmost slot of the plurality of slots may have a second length in the circumferential direction about the tube. The first length may be smaller than the second length. The medical device may further comprise a hub (40) coupled to a proximal portion of the tube. Rotation of the hub may be configured to rotate the proximal portion of the tube about a longitudinal axis of the proximal portion of the tube.
This disclosure pertains to boronated hydrogel compositions, which comprise a boronated polysaccharide compound that comprises a plurality of boronated moieties covalently linked to a carboxylic-acid-containing polysaccharide along a backbone of the carboxylic-acid-containing polysaccharide. The disclosure also pertains to kits that comprise a reservoir, a boronated hydrogel composition comprising a boronated polysaccharide compound that comprises a plurality of boronated moieties covalently linked to a carboxylic-acid-containing polysaccharide along a backbone of the carboxylic-acid-containing polysaccharide disposed in the reservoir, and a device for administering the boronated hydrogel composition to a subject. The disclosure further pertains to methods of treatment that comprise applying or injecting a boronated hydrogel composition comprising a boronated polysaccharide compound that comprises a plurality of boronated moieties covalently linked to a carboxylic-acid-containing polysaccharide along a backbone of the carboxylic-acid-containing polysaccharide onto or into target cells of a subject and delivering neutron beam radiation to the target cells.
A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation
A61K 47/61 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
A61K 47/69 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
Disclosed herein are radiopaque, reactive multi-arm polymers that comprise an iodine-containing core region, a plurality of polymer arms comprising a plurality of polymer segments linked to the iodine-containing core region, and a plurality of reactive moieties linked to the plurality of polymer segments. Also disclosed are methods of forming such radiopaque, reactive multi-arm polymers, systems for forming hydrogel compositions that comprise (a) such radiopaque, reactive multi-arm polymers and (b) multifunctional crosslinking compounds comprising a plurality of complementary reactive moieties that are reactive with the reactive moieties of the radiopaque, reactive multi-arm polymers, as well as reaction products of such systems and methods of treatment using such systems.
A polymeric material having a polyisobutylene polyurethane. The polyisobutylene having soft segments including a polyisobutylene diamine residue, and hard segments including bis-cyclic carbonate residue.
Medical devices and related methods useful for needle access during medical procedures are described. The medical device may include a needle and a handle coupled to the needle, wherein the handle includes a body comprising a radiolucent material, a first marker proximate a proximal end of the body and a second marker proximate a distal end of the body. Each of the first marker and the second marker may include a radiopaque material, and the first marker may have a shape complementary to the second marker to align a position of the needle relative to a subject when visualized by X-ray imaging.
A61M 25/06 - Body-piercing guide needles or the like
A61B 6/12 - Arrangements for detecting or locating foreign bodies
A61M 5/46 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests having means for controlling depth of insertion
Pharmaceutical preparations in the nature of implantable
materials, namely, pliable, synthetic hydrogel for medical
and surgical purposes for the treatment of prostate cancer;
medical device consisting of a pre-polymerized hydrogel for
use in medical and surgical procedures for the treatment of
prostate cancer.
A left atrial appendage (LAA) ligation device is adapted for ligating the LAA via a trans-septal approach, the LAA including an ostium. The LAA ligation device includes a spiral ligation element extending from an end point disposed at a periphery of the spiral ligation element to a center point of the spiral ligation element, the spiral ligation element having a diameter defined by the periphery and a length defined between the periphery and the center point. A delivery device is adapted to releasably secure the spiral ligation element and to enable rotation of the spiral ligation device.
A61B 17/12 - Surgical instruments, devices or methods for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels or umbilical cord
A61B 17/00 - Surgical instruments, devices or methods
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
Medical devices and related methods are described, including a medical device that includes a shaft defining at least one working channel extending from a proximal end of the shaft to a distal end of the shaft along a longitudinal axis and a distal tip coupled to the shaft. The working channel may have a cross-sectional dimension that allows passage of an instrument therethrough. The distal tip may include a first arm and a second arm, the first arm being moveable relative to the second arm between a first configuration that obstructs a portion of the working channel and a second configuration that provides unobstructed access to the working channel, e.g., to allow the instrument to extend distal to the medical device.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
A61B 1/015 - Control of fluid supply or evacuation
A61B 1/018 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor characterised by internal passages or accessories therefor for receiving instruments
A61B 1/05 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor combined with photographic or television appliances characterised by the image sensor, e.g. camera, being in the distal end portion
A61B 1/06 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor with illuminating arrangements
The present disclosure provides medical devices (400) such as self-expanding stents or tissue lumen stents with an overlapping layer. The medical devices can have a coating or cover disposed over all or a portion of the medical device. The overlapping layer define a doubled back portion at an end of the medical device that includes an elongate section (414) to provide dynamic movement of the end of the medical device relative to a central portion (408) of the medical device.
A61B 17/11 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for performing anastomosisButtons for anastomosis
A61B 17/00 - Surgical instruments, devices or methods
93.
SYSTEMS FOR ACCELERATING HYDROLYSIS OF IMPLANTABLE MEDICAL DEVICES
Systems for hydrogel hydrolysis as well as methods for hydrogel hydrolysis are disclosed. An example system may include a syringe barrel having a needle connector disposed thereon. A hydrogel hydrolysis material may be disposed in the syringe barrel. The hydrogel hydrolysis material may be configured to be injected into a hydrogel formed in the body of a patient in order to accelerate the hydrolysis of the hydrogel.
A steerable catheter (10) includes an outer sheath defining an outer sheath lumen extending from a proximal region to a distal region (16). A push ring (22) is secured within the proximal region of the outer sheath lumen. A pull ring (24) is secured within the distal region of the outer sheath lumen. An inner shaft member (30) extends within the outer sheath lumen between the push ring (22) and the pull ring (24). A pair of push members (26a, 26b) extends through the outer sheath lumen and is secured to the push ring (22), each of the pair of push members defining a push member lumen extending therethrough. A pair of pull wires (28a, 28b) are secured to the pull ring (24), each of the pair of pull wires (28a, 28b) extending through one of the push member lumens.
Assistive medical accessories and methods for making and using assistive medical accessories are disclosed. An example assistive medical accessory may include a sterile drape configured for use with a medical device. The sterile drape may have a top surface. A visual indicator may be disposed along the top surface. The visual indicator may be configured to provide use information to a clinician using the medical device.
The present disclosure provides devices and methods to identify locations of side branches in a series of intravascular images (e.g., a pre-treatment IVUS pullback, a post-treatment IVUS pullback, or the like) to assist with co-registering the IVUS images with an extravascular image (e.g., angiogram, or the like) or with another set of IVUS images. The present disclosure further provides devices and methods for training a machine learning (ML) model to infer side branch locations from IVUS images and an analytic algorithm for extracting frames from the IVUS images representing side branches.
Embodiments herein relate to a cryoablation probe including a pre-cooler fluid circuit; a working fluid circuit; a vacuum circuit; and a shaft. The shaft includes a supply tube and a return tube surrounding the supply tube. The return tube includes a first polymer layer, wherein the first polymer layer is configured to contain fluid from the working fluid circuit; a reinforcement layer, and a second polymer layer. Other embodiments are also included herein.
A61B 18/02 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
98.
A SYSTEM AND METHOD FOR QUALITY ASSURANCE OF MEDICAL IMAGE SEGMENTATION
A method and system for reviewing contouring of medical images in a contouring system is described. The method comprising the steps of: providing at least one medical image showing structures to be contoured; generating a contour for a structure on the at least one medical image; determining if the generated contour conforms to guidelines for the structure being contoured; in response to the determining of conformity providing feedback about the quality of the contour; and continuing to generate the contour based on the provided feedback. A method and system for reviewing previously contoured medical images is also described.
A medical device may comprise a sheath configured to be inserted into a body lumen of a patient. A distal end of the sheath may include an elevator for changing an orientation of a medical device. A handle may include an actuator. The actuator may be operably connected to the elevator. Activation of the actuator may cause movement of the elevator. An engaging portion may, in at least one configuration of the handle, protrude from a surface of a handle body toward the actuator. A force exerted by the user on at least one of the actuator or the engaging portion may cause the handle to transition between (a) a first configuration in which the engaging portion interacts with the actuator to inhibit movement of the actuator relative to the engaging portion and (b) a second configuration in which the actuator is movable relative to the engaging portion.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
A61B 1/018 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor characterised by internal passages or accessories therefor for receiving instruments
100.
DEVICE AND METHOD FOR APPLYING A CINCH TO A SUTURE
Medical devices for applying a cinch to a suture and methods for making and using such devices are disclosed. An example medical device may include an elongated shaft including a proximal region and a distal region. The distal region may define a lumen having a lumen dimeter, and a distally facing end surface. The medical device may also include an outer cinch member defining a bore and having an outer surface defining a shoulder. An elongated inner shaft may extend through and be longitudinally movable within the lumen and the bore and including a distal end section. An inner cinch member may be engaged with the distal end section of the elongated inner shaft.
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
